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PRJNA207719: Tissue specific transcriptome profiling

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Results for CABZ01087224.1+hlfb

Z-value: 0.92

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Transcription factors associated with CABZ01087224.1+hlfb

Gene Symbol Gene ID Gene Info
hlfb
ENSDARG00000061011 HLF transcription factor, PAR bZIP family member b
CABZ01087224.1
ENSDARG00000111269 ENSDARG00000111269

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CABZ01087224.1dr11_v1_chr3_+_11568523_11568523-0.335.9e-01Click!
hlfbdr11_v1_chr12_+_32159272_32159272-0.227.2e-01Click!

Activity profile of CABZ01087224.1+hlfb motif

Sorted Z-values of CABZ01087224.1+hlfb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_7735157 0.61 ENSDART00000186717
tuft1b
tuftelin 1b
chr3_-_40275096 0.48 ENSDART00000141578
shmt1
serine hydroxymethyltransferase 1 (soluble)
chr3_+_30921246 0.48 ENSDART00000076850
cldni
claudin i
chr22_+_11775269 0.47 ENSDART00000140272
krt96
keratin 96
chr2_+_10134345 0.45 ENSDART00000100725
ahsg2
alpha-2-HS-glycoprotein 2
chr5_+_45677781 0.45 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr9_-_48736388 0.43 ENSDART00000022074
dhrs9
dehydrogenase/reductase (SDR family) member 9
chr5_+_43782267 0.39 ENSDART00000130355
nos2a
nitric oxide synthase 2a, inducible
chr14_+_3507326 0.38 ENSDART00000159326
gstp1
glutathione S-transferase pi 1
chr7_+_12950507 0.37 ENSDART00000067629
ENSDART00000158004
saa
serum amyloid A
chr16_-_45917322 0.37 ENSDART00000060822
afp4
antifreeze protein type IV
chr8_-_21103041 0.37 ENSDART00000171771
ENSDART00000131322
ENSDART00000137838
aldh9a1a.1
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr13_-_36034582 0.36 ENSDART00000133565
si:dkey-157l19.2
si:dkey-157l19.2
chr22_+_11756040 0.36 ENSDART00000105808
krt97
keratin 97
chr19_+_43715911 0.32 ENSDART00000006344
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr8_-_21103522 0.32 ENSDART00000100283
aldh9a1a.1
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr16_-_45917683 0.32 ENSDART00000184289
afp4
antifreeze protein type IV
chr22_-_17677947 0.31 ENSDART00000139911
tjp3
tight junction protein 3
chr5_+_22974019 0.31 ENSDART00000147157
ENSDART00000020434
brwd3
bromodomain and WD repeat domain containing 3
chr5_-_69212184 0.30 ENSDART00000053963
mat2ab
methionine adenosyltransferase II, alpha b
chr25_-_13202208 0.29 ENSDART00000168155
si:ch211-194m7.4
si:ch211-194m7.4
chr8_-_50147948 0.29 ENSDART00000149010
hp
haptoglobin
chr16_-_29387215 0.29 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr4_+_5531583 0.28 ENSDART00000137500
ENSDART00000042080
si:dkey-14d8.6
si:dkey-14d8.6
chr7_+_15736230 0.28 ENSDART00000109942
mctp2b
multiple C2 domains, transmembrane 2b
chr4_-_12725513 0.28 ENSDART00000132286
mgst1.2
microsomal glutathione S-transferase 1.2
chr19_+_4990320 0.26 ENSDART00000147056
zgc:91968
zgc:91968
chr11_+_43419809 0.26 ENSDART00000172982
slc29a1b
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr3_-_57744323 0.26 ENSDART00000101829
lgals3bpb
lectin, galactoside-binding, soluble, 3 binding protein b
chr7_+_38380135 0.25 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr22_+_26443235 0.25 ENSDART00000044085
zgc:92480
zgc:92480
chr19_-_17210760 0.25 ENSDART00000007906
stmn1a
stathmin 1a
chr22_+_24645325 0.24 ENSDART00000159531
lpar3
lysophosphatidic acid receptor 3
chr14_+_32430982 0.24 ENSDART00000017179
ENSDART00000123382
ENSDART00000075593
f9a
coagulation factor IXa
chr17_+_26965351 0.24 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr7_-_12968689 0.24 ENSDART00000173115
ENSDART00000013690
rplp2l
ribosomal protein, large P2, like
chr24_+_38671054 0.24 ENSDART00000154214
si:ch73-70c5.1
si:ch73-70c5.1
chr13_-_25196758 0.24 ENSDART00000184722
adka
adenosine kinase a
chr24_-_26328721 0.24 ENSDART00000125468
apodb
apolipoprotein Db
chr13_+_25396896 0.23 ENSDART00000041257
gsto2
glutathione S-transferase omega 2
chr10_-_15053507 0.23 ENSDART00000157446
ENSDART00000170441
CLDN23
si:ch211-95j8.5
chr22_+_10606863 0.22 ENSDART00000147975
rad54l2
RAD54 like 2
chr5_+_6955900 0.22 ENSDART00000099417
CABZ01041962.1

chr21_+_25625026 0.22 ENSDART00000134678
ovol1b
ovo-like zinc finger 1b
chr14_+_21699414 0.22 ENSDART00000169942
stx3a
syntaxin 3A
chr22_+_10606573 0.21 ENSDART00000192638
rad54l2
RAD54 like 2
chr4_+_5196469 0.21 ENSDART00000067386
rad51ap1
RAD51 associated protein 1
chr2_-_19234329 0.21 ENSDART00000161106
ENSDART00000160060
ENSDART00000174552
cdc20
cell division cycle 20 homolog
chr20_+_35857399 0.21 ENSDART00000102611
cd2ap
CD2-associated protein
chr22_-_817479 0.21 ENSDART00000123487
zgc:153675
zgc:153675
chr19_-_17210928 0.21 ENSDART00000164683
stmn1a
stathmin 1a
chr11_+_25504215 0.21 ENSDART00000154213
tfe3b
transcription factor binding to IGHM enhancer 3b
chr13_+_25397098 0.20 ENSDART00000132953
gsto2
glutathione S-transferase omega 2
chr9_+_41218967 0.20 ENSDART00000000280
ENSDART00000145674
stat1b
signal transducer and activator of transcription 1b
chr6_-_39649504 0.20 ENSDART00000179960
ENSDART00000190951
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr5_+_25585869 0.20 ENSDART00000138060
si:dkey-229d2.7
si:dkey-229d2.7
chr25_-_29415369 0.20 ENSDART00000110774
ENSDART00000019183
ugt5a2
ugt5a1
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr6_+_53288018 0.19 ENSDART00000170319
cysltr3
cysteinyl leukotriene receptor 3
chr2_+_35595454 0.19 ENSDART00000098734
cacybp
calcyclin binding protein
chr24_-_17023392 0.19 ENSDART00000106058
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr22_+_15336752 0.19 ENSDART00000139070
sult3st2
sulfotransferase family 3, cytosolic sulfotransferase 2
chr9_-_32300783 0.18 ENSDART00000078596
hspd1
heat shock 60 protein 1
chr19_+_4990496 0.18 ENSDART00000151050
ENSDART00000017535
zgc:91968
zgc:91968
chr5_-_36948586 0.18 ENSDART00000193606
h3f3c
H3 histone, family 3C
chr21_-_27443995 0.18 ENSDART00000003508
bfb
complement component bfb
chr12_+_22657925 0.18 ENSDART00000153048
si:dkey-219e21.4
si:dkey-219e21.4
chr1_-_10071422 0.18 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr9_-_9225980 0.18 ENSDART00000180301
cbsb
cystathionine-beta-synthase b
chr6_-_10752937 0.18 ENSDART00000135093
ola1
Obg-like ATPase 1
chr16_-_383664 0.18 ENSDART00000051693
irx4a
iroquois homeobox 4a
chr6_+_42475730 0.18 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr7_+_56577522 0.18 ENSDART00000149130
ENSDART00000149624
hp
haptoglobin
chr17_-_10838434 0.18 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr6_+_16468776 0.17 ENSDART00000109151
ENSDART00000114667
zgc:161969
zgc:161969
chr5_-_63509581 0.17 ENSDART00000097325
c5
complement component 5
chr22_+_15315655 0.17 ENSDART00000141249
sult3st3
sulfotransferase family 3, cytosolic sulfotransferase 3
chr15_+_19838458 0.17 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr10_-_23099809 0.17 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
nle1
notchless homolog 1 (Drosophila)
chr9_-_44953349 0.17 ENSDART00000135156
vil1
villin 1
chr20_-_25522911 0.17 ENSDART00000063058
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr16_-_51253925 0.17 ENSDART00000050644
serpinb14
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr1_-_58887610 0.17 ENSDART00000180647
CABZ01084501.1
microfibril-associated glycoprotein 4-like precursor
chr3_-_26183699 0.17 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr18_+_25546227 0.16 ENSDART00000085824
pex11a
peroxisomal biogenesis factor 11 alpha
chr2_+_44348473 0.16 ENSDART00000155166
ENSDART00000098146
zgc:152670
zgc:152670
chr24_-_23784701 0.16 ENSDART00000090368
sgk3
serum/glucocorticoid regulated kinase family, member 3
chr12_+_37401331 0.16 ENSDART00000125040
si:ch211-152f22.4
si:ch211-152f22.4
chr21_-_33126697 0.16 ENSDART00000189293
ENSDART00000084559
CU019662.1

chr6_+_36381709 0.16 ENSDART00000004727
rhcgl1
Rh family, C glycoprotein, like 1
chr5_+_29831235 0.16 ENSDART00000109660
f11r.1
F11 receptor, tandem duplicate 1
chr4_+_77973876 0.16 ENSDART00000057423
terfa
telomeric repeat binding factor a
chr6_-_26895750 0.16 ENSDART00000011863
hdlbpa
high density lipoprotein binding protein a
chr5_-_11809404 0.15 ENSDART00000132564
nf2a
neurofibromin 2a (merlin)
chr15_-_23546452 0.15 ENSDART00000100669
si:dkey-182i3.11
si:dkey-182i3.11
chr15_-_1765098 0.15 ENSDART00000149980
ENSDART00000093074
bud23
BUD23, rRNA methyltransferase and ribosome maturation factor
chr7_+_53156810 0.15 ENSDART00000189816
cdh29
cadherin 29
chr24_-_26310854 0.15 ENSDART00000080113
apodb
apolipoprotein Db
chr23_-_43486714 0.15 ENSDART00000169726
e2f1
E2F transcription factor 1
chr24_+_26329018 0.14 ENSDART00000145752
mynn
myoneurin
chr12_+_19199735 0.14 ENSDART00000066393
pdap1a
pdgfa associated protein 1a
chr21_+_1647990 0.14 ENSDART00000148540
fech
ferrochelatase
chr24_+_26328787 0.14 ENSDART00000003884
mynn
myoneurin
chr19_+_43716607 0.14 ENSDART00000133199
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr8_+_4838114 0.14 ENSDART00000146667
es1
es1 protein
chr13_+_18533005 0.14 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr1_+_16600690 0.14 ENSDART00000162164
mtus1b
microtubule associated tumor suppressor 1b
chr6_+_50451337 0.14 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr9_-_32300611 0.14 ENSDART00000127938
hspd1
heat shock 60 protein 1
chr4_+_17353714 0.14 ENSDART00000136299
nup37
nucleoporin 37
chr4_+_5341592 0.14 ENSDART00000123375
ENSDART00000067371
zgc:113263
zgc:113263
chr4_+_9478500 0.14 ENSDART00000030738
lmf2b
lipase maturation factor 2b
chr23_+_11285662 0.14 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr3_-_26184018 0.14 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr14_+_4151379 0.14 ENSDART00000160431
dhrs13l1
dehydrogenase/reductase (SDR family) member 13 like 1
chr1_-_23274038 0.14 ENSDART00000181658
rfc1
replication factor C (activator 1) 1
chr20_-_25533739 0.14 ENSDART00000063064
cyp2ad6
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr4_-_27099224 0.13 ENSDART00000048383
creld2
cysteine-rich with EGF-like domains 2
chr5_-_14521500 0.13 ENSDART00000176565
si:ch211-244o22.2
si:ch211-244o22.2
chr25_+_3104959 0.13 ENSDART00000167130
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr7_+_22792895 0.13 ENSDART00000184407
rbm4.3
RNA binding motif protein 4.3
chr3_+_1107102 0.13 ENSDART00000092690
srebf2
sterol regulatory element binding transcription factor 2
chr7_-_3429874 0.13 ENSDART00000132330
si:ch211-285c6.1
si:ch211-285c6.1
chr14_+_21699129 0.13 ENSDART00000073707
stx3a
syntaxin 3A
chr13_-_10945288 0.13 ENSDART00000114315
ENSDART00000164667
ENSDART00000159482
abcg8
ATP-binding cassette, sub-family G (WHITE), member 8
chr23_-_18981595 0.13 ENSDART00000147617
bcl2l1
bcl2-like 1
chr17_-_6198823 0.13 ENSDART00000028407
ENSDART00000193636
ptk2ba
protein tyrosine kinase 2 beta, a
chr2_-_37277626 0.13 ENSDART00000135340
nadkb
NAD kinase b
chr6_+_9130989 0.13 ENSDART00000162588
rgn
regucalcin
chr9_-_11550711 0.13 ENSDART00000093343
fev
FEV (ETS oncogene family)
chr19_-_30810328 0.13 ENSDART00000184875
myclb
MYCL proto-oncogene, bHLH transcription factor b
chr25_+_36292465 0.13 ENSDART00000152649
bmb
brambleberry
chr16_+_23397785 0.13 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr6_-_1553314 0.13 ENSDART00000077209
tpra1
transmembrane protein, adipocyte asscociated 1
chr19_+_14109348 0.13 ENSDART00000159015
zgc:175136
zgc:175136
chr7_+_46019780 0.12 ENSDART00000163991
ccne1
cyclin E1
chr19_-_3056235 0.12 ENSDART00000137020
bop1
block of proliferation 1
chr10_+_38417512 0.12 ENSDART00000112457
samsn1b
SAM domain, SH3 domain and nuclear localisation signals 1b
chr6_+_29791164 0.12 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr12_-_13205854 0.12 ENSDART00000077829
pelo
pelota mRNA surveillance and ribosome rescue factor
chr12_-_13205572 0.12 ENSDART00000152670
pelo
pelota mRNA surveillance and ribosome rescue factor
chr8_+_12930216 0.12 ENSDART00000115405
KIF2A
zgc:103670
chr13_+_10945337 0.12 ENSDART00000091845
abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr14_+_16345003 0.12 ENSDART00000003040
ENSDART00000165193
itln3
intelectin 3
chr5_-_36949476 0.12 ENSDART00000047269
h3f3c
H3 histone, family 3C
chr25_-_13188678 0.12 ENSDART00000125754
si:ch211-147m6.1
si:ch211-147m6.1
chr19_+_14113886 0.12 ENSDART00000169343
kdf1b
keratinocyte differentiation factor 1b
chr9_+_13682133 0.12 ENSDART00000175639
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr9_-_12888082 0.11 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr2_-_55779927 0.11 ENSDART00000168579
CABZ01066725.1

chr11_+_12744575 0.11 ENSDART00000131059
ENSDART00000081335
ENSDART00000142481
rbb4l
retinoblastoma binding protein 4, like
chr7_+_67733759 0.11 ENSDART00000172015
cyb5b
cytochrome b5 type B
chr6_-_32411703 0.11 ENSDART00000151002
ENSDART00000078908
usp1
ubiquitin specific peptidase 1
chr11_-_23459779 0.11 ENSDART00000183935
ENSDART00000184125
ENSDART00000193284
plekha6
pleckstrin homology domain containing, family A member 6
chr16_-_6849754 0.11 ENSDART00000149206
ENSDART00000149778
mbpb
myelin basic protein b
chr8_-_25846188 0.11 ENSDART00000128829
efhd2
EF-hand domain family, member D2
chr9_+_38292947 0.11 ENSDART00000146663
tfcp2l1
transcription factor CP2-like 1
chr12_-_20584413 0.11 ENSDART00000170923
FP885542.2

chr4_+_30785713 0.11 ENSDART00000165945
si:dkey-178j11.5
si:dkey-178j11.5
chr8_-_42594380 0.11 ENSDART00000140126
ENSDART00000135238
ENSDART00000192764
dok2
docking protein 2
chr18_-_16922905 0.11 ENSDART00000187165
wee1
WEE1 G2 checkpoint kinase
chr16_+_23398369 0.11 ENSDART00000037694
s100a10b
S100 calcium binding protein A10b
chr9_+_30478768 0.11 ENSDART00000101097
acp6
acid phosphatase 6, lysophosphatidic
chr19_-_24757231 0.11 ENSDART00000128177
si:dkey-154b15.1
si:dkey-154b15.1
chr20_-_9760424 0.11 ENSDART00000104936
si:dkey-63j12.4
si:dkey-63j12.4
chr9_+_21306902 0.11 ENSDART00000138554
ENSDART00000004108
xpo4
exportin 4
chr3_+_40284598 0.11 ENSDART00000009411
bud31
BUD31 homolog (S. cerevisiae)
chr19_-_30811161 0.11 ENSDART00000103524
myclb
MYCL proto-oncogene, bHLH transcription factor b
chr18_-_7448047 0.11 ENSDART00000193213
ENSDART00000131940
ENSDART00000186944
ENSDART00000052803
si:dkey-30c15.10
si:dkey-30c15.10
chr13_-_25774183 0.11 ENSDART00000046981
pdlim1
PDZ and LIM domain 1 (elfin)
chr1_+_14253118 0.11 ENSDART00000161996
cxcl8a
chemokine (C-X-C motif) ligand 8a
chr20_+_2039518 0.11 ENSDART00000043157
CABZ01088134.1

chr16_-_19568388 0.11 ENSDART00000141616
abcb5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr21_+_45841731 0.10 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr9_+_18023288 0.10 ENSDART00000098355
tnfsf11
TNF superfamily member 11
chr15_+_12435975 0.10 ENSDART00000168011
tmprss4a
transmembrane protease, serine 4a
chr22_-_10605045 0.10 ENSDART00000184812
bap1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr6_-_48347724 0.10 ENSDART00000046973
capza1a
capping protein (actin filament) muscle Z-line, alpha 1a
chr5_-_2721686 0.10 ENSDART00000169404
hspa5
heat shock protein 5
chr22_+_1123873 0.10 ENSDART00000137708
si:ch1073-181h11.2
si:ch1073-181h11.2
chr4_+_39766931 0.10 ENSDART00000138663
si:dkeyp-85d8.1
si:dkeyp-85d8.1
chr8_-_37249813 0.10 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
rbm39b
RNA binding motif protein 39b
chr8_+_247163 0.10 ENSDART00000122378
cep120
centrosomal protein 120
chr8_+_22472584 0.10 ENSDART00000138303
si:dkey-23c22.9
si:dkey-23c22.9
chr19_+_12649691 0.10 ENSDART00000192956
ENSDART00000088917
rnmt
RNA (guanine-7-) methyltransferase
chr11_-_23501467 0.10 ENSDART00000169066
plekha6
pleckstrin homology domain containing, family A member 6
chr13_-_42536642 0.10 ENSDART00000134533
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr10_+_39283985 0.10 ENSDART00000016464
dcps
decapping enzyme, scavenger
chr14_+_8174828 0.10 ENSDART00000167228
psd2
pleckstrin and Sec7 domain containing 2
chr10_+_23099890 0.10 ENSDART00000135890
LTN1
si:dkey-175g6.5
chr19_+_16015881 0.10 ENSDART00000187135
ctps1a
CTP synthase 1a
chr24_-_26854032 0.10 ENSDART00000087991
fndc3bb
fibronectin type III domain containing 3Bb
chr25_-_26833100 0.10 ENSDART00000014052
neil1
nei-like DNA glycosylase 1
chr5_-_30074332 0.10 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr7_+_46020508 0.10 ENSDART00000170294
ccne1
cyclin E1
chr9_-_11551608 0.10 ENSDART00000128629
fev
FEV (ETS oncogene family)
chr7_-_21887104 0.10 ENSDART00000019699
mettl3
methyltransferase like 3
chr17_-_20236228 0.10 ENSDART00000136490
ENSDART00000029380
bnip4
BCL2 interacting protein 4
chr13_-_10620652 0.10 ENSDART00000135000
ENSDART00000191587
si:ch73-54n14.2
camkmt
si:ch73-54n14.2
calmodulin-lysine N-methyltransferase
chr25_+_34845115 0.10 ENSDART00000061996
tmem231
transmembrane protein 231
chr7_+_22853788 0.09 ENSDART00000148502
clcn5b
chloride channel, voltage-sensitive 5b

Network of associatons between targets according to the STRING database.

First level regulatory network of CABZ01087224.1+hlfb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0006565 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.1 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.3 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.4 GO:0031282 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.4 GO:0051818 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.1 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.2 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.0 0.3 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.2 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.2 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.5 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cyclic nucleotide metabolic process(GO:0030801) positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of cyclase activity(GO:0031281) positive regulation of adenylate cyclase activity(GO:0045762) positive regulation of lyase activity(GO:0051349) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.7 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0002544 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.0 0.2 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 0.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.0 0.3 GO:0030104 water homeostasis(GO:0030104)
0.0 0.1 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.4 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0019474 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.2 GO:0021885 forebrain cell migration(GO:0021885)
0.0 0.8 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.1 GO:0005991 trehalose metabolic process(GO:0005991)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.1 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.0 0.1 GO:0046436 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.2 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.4 GO:0051180 vitamin transport(GO:0051180)
0.0 0.1 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.1 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.1 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.0 0.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.4 GO:0007568 aging(GO:0007568)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.3 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.0 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.0 GO:0097268 cytoophidium(GO:0097268)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.2 0.5 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.2 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 0.5 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.2 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.2 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.1 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.1 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.0 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.0 0.1 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.0 GO:0003883 CTP synthase activity(GO:0003883)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation