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PRJNA207719: Tissue specific transcriptome profiling

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Results for SPDEF

Z-value: 1.23

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Transcription factors associated with SPDEF

Gene Symbol Gene ID Gene Info
SPDEF
ENSDARG00000029930 SAM pointed domain containing ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPDEFdr11_v1_chr6_-_54290227_542902270.513.8e-01Click!

Activity profile of SPDEF motif

Sorted Z-values of SPDEF motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_37118547 0.25 ENSDART00000103163
cx30.9
connexin 30.9
chr17_-_27382826 0.25 ENSDART00000186657
ENSDART00000155986
ENSDART00000191060
ENSDART00000077608
si:ch1073-358c10.1
si:ch1073-358c10.1
chr17_+_33375469 0.23 ENSDART00000032827
zgc:162964
zgc:162964
chr8_+_23726244 0.22 ENSDART00000132734
mkrn4
makorin, ring finger protein, 4
chr5_+_44346691 0.22 ENSDART00000034523
tars
threonyl-tRNA synthetase
chr8_+_23726708 0.21 ENSDART00000142395
mkrn4
makorin, ring finger protein, 4
chr20_+_52492192 0.20 ENSDART00000057986
TSTA3 (1 of many)
zgc:100864
chr8_-_17184482 0.19 ENSDART00000025803
pola2
polymerase (DNA directed), alpha 2
chr21_-_19828423 0.19 ENSDART00000037664
nnt
nicotinamide nucleotide transhydrogenase
chr20_+_39685572 0.19 ENSDART00000050729
hddc2
HD domain containing 2
chr22_+_5663529 0.19 ENSDART00000106141
tma7
translation machinery associated 7 homolog
chr2_+_4383061 0.19 ENSDART00000163986
wacb
WW domain containing adaptor with coiled-coil b
chr4_-_18954001 0.18 ENSDART00000144814
si:dkey-31f5.8
si:dkey-31f5.8
chr7_+_59649399 0.18 ENSDART00000123520
ENSDART00000040771
rpl34
ribosomal protein L34
chr15_+_46313082 0.18 ENSDART00000153830
si:ch1073-190k2.1
si:ch1073-190k2.1
chr22_-_5663354 0.18 ENSDART00000081774
ccdc51
coiled-coil domain containing 51
chr23_-_33775145 0.18 ENSDART00000132147
ENSDART00000027959
ENSDART00000160116
racgap1
Rac GTPase activating protein 1
chr21_-_30994577 0.18 ENSDART00000065503
pgap2
post-GPI attachment to proteins 2
chr13_-_12494575 0.18 ENSDART00000137761
si:dkey-20i10.7
si:dkey-20i10.7
chr23_+_16928506 0.18 ENSDART00000162292
ENSDART00000080625
si:dkey-147f3.4
si:dkey-147f3.4
chr3_+_30980852 0.17 ENSDART00000028529
prf1.1
perforin 1.1
chr19_+_9455218 0.17 ENSDART00000139385
si:ch211-288g17.3
si:ch211-288g17.3
chr19_+_34230108 0.17 ENSDART00000141950
galnt12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr23_-_40250886 0.17 ENSDART00000041912
tgm1l3
transglutaminase 1 like 3
chr6_-_29288155 0.17 ENSDART00000078630
nme7
NME/NM23 family member 7
chr2_+_49457626 0.17 ENSDART00000129967
sh3gl1a
SH3-domain GRB2-like 1a
chr3_-_40276057 0.16 ENSDART00000132225
ENSDART00000074737
shmt1
serine hydroxymethyltransferase 1 (soluble)
chr21_-_40938382 0.16 ENSDART00000008593
yipf5
Yip1 domain family, member 5
chr11_-_15296805 0.16 ENSDART00000124968
rpn2
ribophorin II
chr23_+_9867483 0.16 ENSDART00000023099
slc16a7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr24_-_32522587 0.16 ENSDART00000048968
ENSDART00000143781
EIF1B
zgc:56676
chr2_+_49457449 0.16 ENSDART00000185470
sh3gl1a
SH3-domain GRB2-like 1a
chr6_+_4387150 0.15 ENSDART00000181283
rbm26
RNA binding motif protein 26
chr4_+_9612574 0.15 ENSDART00000150336
ENSDART00000041289
ENSDART00000150828
tmem243b
transmembrane protein 243, mitochondrial b
chr19_-_35428815 0.15 ENSDART00000169006
ENSDART00000003167
ak2
adenylate kinase 2
chr8_-_41279326 0.15 ENSDART00000075491
pop5
POP5 homolog, ribonuclease P/MRP subunit
chr21_-_36619599 0.15 ENSDART00000065208
nop16
NOP16 nucleolar protein homolog (yeast)
chr4_-_22749553 0.15 ENSDART00000040033
nup107
nucleoporin 107
chr24_-_10897511 0.15 ENSDART00000145593
ENSDART00000102484
ENSDART00000066784
fam49bb
family with sequence similarity 49, member Bb
chr12_+_46543572 0.15 ENSDART00000167510
hid1b
HID1 domain containing b
chr21_-_32436679 0.15 ENSDART00000076974
gfpt2
glutamine-fructose-6-phosphate transaminase 2
chr20_+_39344889 0.14 ENSDART00000009164
esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr5_+_26795773 0.14 ENSDART00000145631
tcn2
transcobalamin II
chr22_-_20950448 0.14 ENSDART00000002029
fkbp8
FK506 binding protein 8
chr19_-_34089205 0.14 ENSDART00000163618
ENSDART00000161666
rp9
RP9, pre-mRNA splicing factor
chr16_+_12812472 0.14 ENSDART00000008535
u2af2a
U2 small nuclear RNA auxiliary factor 2a
chr2_-_20052561 0.14 ENSDART00000100133
dpydb
dihydropyrimidine dehydrogenase b
chr20_-_20611063 0.14 ENSDART00000063492
ppm1ab
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr16_+_54829574 0.14 ENSDART00000148392
pabpc1a
poly(A) binding protein, cytoplasmic 1a
chr23_-_24234371 0.14 ENSDART00000124539
ddost
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr13_-_5569562 0.14 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr1_+_49435017 0.14 ENSDART00000124833
pdcd11
programmed cell death 11
chr13_+_31545812 0.13 ENSDART00000076527
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr11_-_15297129 0.13 ENSDART00000167985
ENSDART00000163031
ENSDART00000165010
ENSDART00000171250
ENSDART00000010684
ENSDART00000191714
ENSDART00000191164
rpn2
ribophorin II
chr9_-_28255029 0.13 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr19_+_43004408 0.13 ENSDART00000038230
snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr23_+_4260458 0.13 ENSDART00000103747
srsf6a
serine/arginine-rich splicing factor 6a
chr5_-_23117078 0.13 ENSDART00000051529
uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr19_+_7735157 0.13 ENSDART00000186717
tuft1b
tuftelin 1b
chr8_-_53680653 0.13 ENSDART00000164739
wnt5a
wingless-type MMTV integration site family, member 5a
chr1_+_47165842 0.13 ENSDART00000053152
ENSDART00000167051
cbr1
carbonyl reductase 1
chr12_+_29240124 0.13 ENSDART00000053761
ENSDART00000130172
bms1
BMS1 ribosome biogenesis factor
chr12_-_14211293 0.13 ENSDART00000158399
avl9
AVL9 homolog (S. cerevisiase)
chr7_-_57637779 0.13 ENSDART00000028017
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr23_-_30764319 0.13 ENSDART00000075918
pcmtd2
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr7_+_59649746 0.13 ENSDART00000181067
rpl34
ribosomal protein L34
chr14_-_5407555 0.13 ENSDART00000001424
pcgf1
polycomb group ring finger 1
chr18_-_22735002 0.13 ENSDART00000023721
nudt21
nudix hydrolase 21
chr13_+_31545530 0.13 ENSDART00000164590
ENSDART00000178460
ENSDART00000185503
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr11_-_16975190 0.13 ENSDART00000122222
suclg2
succinate-CoA ligase, GDP-forming, beta subunit
chr2_+_42212948 0.13 ENSDART00000147019
si:ch211-235o23.1
si:ch211-235o23.1
chr2_-_2642476 0.13 ENSDART00000124032
serbp1b
SERPINE1 mRNA binding protein 1b
chr18_+_29898955 0.13 ENSDART00000064080
cenpn
centromere protein N
chr3_-_3398383 0.13 ENSDART00000047865
si:dkey-46g23.2
si:dkey-46g23.2
chr3_-_27065477 0.13 ENSDART00000185660
atf7ip2
activating transcription factor 7 interacting protein 2
chr16_-_44673851 0.12 ENSDART00000015139
dcaf13
ddb1 and cul4 associated factor 13
chr20_-_23946296 0.12 ENSDART00000143005
mdn1
midasin AAA ATPase 1
chr1_+_46598502 0.12 ENSDART00000132861
cab39l
calcium binding protein 39-like
chr6_-_18531349 0.12 ENSDART00000160693
ENSDART00000169780
utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr25_-_17239008 0.12 ENSDART00000151965
ENSDART00000152106
ENSDART00000152107
ccnd2a
cyclin D2, a
chr16_+_12812214 0.12 ENSDART00000124875
u2af2a
U2 small nuclear RNA auxiliary factor 2a
chr2_-_45510699 0.12 ENSDART00000024034
ENSDART00000145634
gpsm2
G protein signaling modulator 2
chr14_-_10617923 0.12 ENSDART00000133723
ENSDART00000131939
ENSDART00000136649
si:dkey-92i17.2
si:dkey-92i17.2
chr21_+_26539157 0.12 ENSDART00000021121
stx5al
syntaxin 5A, like
chr24_-_26369185 0.12 ENSDART00000080039
lrrc31
leucine rich repeat containing 31
chr18_+_6638726 0.11 ENSDART00000142755
ENSDART00000167781
c2cd5
C2 calcium-dependent domain containing 5
chr2_-_43130812 0.11 ENSDART00000039079
ENSDART00000056162
ftr13
finTRIM family, member 13
chr12_-_14211067 0.11 ENSDART00000077903
avl9
AVL9 homolog (S. cerevisiase)
chr2_+_32846602 0.11 ENSDART00000056649
tmem53
transmembrane protein 53
chr23_-_4225606 0.11 ENSDART00000014152
ENSDART00000133341
aar2
AAR2 splicing factor homolog (S. cerevisiae)
chr2_-_42173834 0.11 ENSDART00000098357
ENSDART00000144707
slc39a6
solute carrier family 39 (zinc transporter), member 6
chr6_-_54433995 0.11 ENSDART00000017230
snrpc
small nuclear ribonucleoprotein polypeptide C
chr13_-_42673978 0.11 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr5_+_54555567 0.11 ENSDART00000171159
anapc2
anaphase promoting complex subunit 2
chr5_+_51833305 0.11 ENSDART00000165276
ENSDART00000166443
papd4
PAP associated domain containing 4
chr18_+_6638974 0.11 ENSDART00000162398
c2cd5
C2 calcium-dependent domain containing 5
chr5_-_67292690 0.11 ENSDART00000062366
rsrc2
arginine/serine-rich coiled-coil 2
chr9_+_25853052 0.10 ENSDART00000127135
gtdc1
glycosyltransferase-like domain containing 1
chr9_-_36924388 0.10 ENSDART00000059756
ralba
v-ral simian leukemia viral oncogene homolog Ba (ras related)
chr5_+_64856666 0.10 ENSDART00000050863
zgc:101858
zgc:101858
chr6_+_3334710 0.10 ENSDART00000132848
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr20_+_715739 0.10 ENSDART00000136768
myo6a
myosin VIa
chr25_+_8921425 0.10 ENSDART00000128591
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr24_+_41281265 0.10 ENSDART00000156920
ENSDART00000155151
nub1
negative regulator of ubiquitin-like proteins 1
chr2_-_45510223 0.10 ENSDART00000113058
gpsm2
G protein signaling modulator 2
chr18_-_26797723 0.10 ENSDART00000008013
sec11a
SEC11 homolog A, signal peptidase complex subunit
chr13_-_33654931 0.10 ENSDART00000020350
snx5
sorting nexin 5
chr3_+_36617024 0.10 ENSDART00000189957
pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
chr17_+_8754020 0.10 ENSDART00000105322
edrf1
erythroid differentiation regulatory factor 1
chr18_-_39321484 0.09 ENSDART00000077694
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component
chr6_-_29159888 0.09 ENSDART00000110288
zbtb11
zinc finger and BTB domain containing 11
chr3_-_24681404 0.09 ENSDART00000161612
BX569789.1

chr3_-_34113838 0.09 ENSDART00000151216
ighv4-2
immunoglobulin heavy variable 4-2
chr19_-_1871415 0.09 ENSDART00000004585
clptm1l
CLPTM1-like
chr16_-_31824525 0.09 ENSDART00000058737
cdc42l
cell division cycle 42, like
chr20_-_16223245 0.09 ENSDART00000014721
echdc2
enoyl CoA hydratase domain containing 2
chr22_-_10752471 0.09 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr24_-_37640705 0.09 ENSDART00000066583
zgc:112496
zgc:112496
chr2_+_48303142 0.09 ENSDART00000023040
hes6
hes family bHLH transcription factor 6
chr22_+_2959879 0.09 ENSDART00000185354
ENSDART00000063545
impact
impact RWD domain protein
chr12_-_9468618 0.08 ENSDART00000152737
ENSDART00000091519
pgap3
post-GPI attachment to proteins 3
chr1_+_12335816 0.08 ENSDART00000067086
nansa
N-acetylneuraminic acid synthase a
chr20_-_48898560 0.08 ENSDART00000163071
xrn2
5'-3' exoribonuclease 2
chr13_-_18069421 0.08 ENSDART00000146772
ENSDART00000134477
zfand4
zinc finger, AN1-type domain 4
chr10_+_43037064 0.08 ENSDART00000160159
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr20_-_20610812 0.08 ENSDART00000181870
ppm1ab
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr4_-_12978925 0.08 ENSDART00000013839
tmbim4
transmembrane BAX inhibitor motif containing 4
chr2_-_56095275 0.08 ENSDART00000154701
si:ch211-178n15.1
si:ch211-178n15.1
chr19_-_34742440 0.08 ENSDART00000122625
ENSDART00000175621
elp2
elongator acetyltransferase complex subunit 2
chr3_+_32425202 0.08 ENSDART00000156464
prr12b
proline rich 12b
chr14_-_5407118 0.08 ENSDART00000168074
pcgf1
polycomb group ring finger 1
chr25_+_17920668 0.08 ENSDART00000093358
borcs5
BLOC-1 related complex subunit 5
chr7_-_32629458 0.08 ENSDART00000001376
arl14ep
ADP-ribosylation factor-like 14 effector protein
chr22_+_8753092 0.08 ENSDART00000140720
si:dkey-182g1.2
si:dkey-182g1.2
chr8_-_33154677 0.08 ENSDART00000133300
zbtb34
zinc finger and BTB domain containing 34
chr15_-_34933560 0.08 ENSDART00000006288
dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr23_-_32404022 0.08 ENSDART00000156387
ENSDART00000155508
si:ch211-66i15.4
si:ch211-66i15.4
chr8_-_17987547 0.08 ENSDART00000112699
ENSDART00000061747
fpgt
fucose-1-phosphate guanylyltransferase
chr15_-_29114449 0.08 ENSDART00000145748
ENSDART00000109482
ENSDART00000179123
zgc:162698
zgc:162698
chr24_+_17069420 0.08 ENSDART00000014787
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr6_-_54444929 0.07 ENSDART00000154121
sys1
Sys1 golgi trafficking protein
chr14_-_31856819 0.07 ENSDART00000003345
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr18_+_27000850 0.07 ENSDART00000188906
ENSDART00000086131
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr14_-_30897177 0.07 ENSDART00000087918
slc7a3b
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3b
chr4_-_1824836 0.07 ENSDART00000111858
mrpl42
mitochondrial ribosomal protein L42
chr14_+_712115 0.07 ENSDART00000157494
ENSDART00000166516
ENSDART00000082017
ENSDART00000122374
ENSDART00000170203
ints10
integrator complex subunit 10
chr15_-_34668485 0.07 ENSDART00000186605
bag6
BCL2 associated athanogene 6
chr7_-_29356084 0.07 ENSDART00000075757
gtf2a2
general transcription factor IIA, 2
chr18_+_27001115 0.07 ENSDART00000133547
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr15_+_38299563 0.07 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr3_+_59880317 0.07 ENSDART00000166922
ENSDART00000108647
alyref
Aly/REF export factor
chr21_-_22892124 0.07 ENSDART00000065563
ccdc90b
coiled-coil domain containing 90B
chr14_-_43616572 0.07 ENSDART00000111189
gar1
GAR1 homolog, ribonucleoprotein
chr6_-_49526510 0.07 ENSDART00000128025
rps26l
ribosomal protein S26, like
chr1_+_24557414 0.07 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr7_-_20103384 0.07 ENSDART00000052902
acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr14_+_23687678 0.07 ENSDART00000002469
hspa4b
heat shock protein 4b
chr8_+_39770162 0.07 ENSDART00000190677
hps4
Hermansky-Pudlak syndrome 4
chr16_+_54829293 0.07 ENSDART00000024729
pabpc1a
poly(A) binding protein, cytoplasmic 1a
chr6_-_2222707 0.07 ENSDART00000022179
prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr24_-_7826489 0.07 ENSDART00000112777
si:dkey-197c15.6
si:dkey-197c15.6
chr5_-_26795438 0.07 ENSDART00000146124
si:ch211-102c2.7
si:ch211-102c2.7
chr11_+_6374448 0.07 ENSDART00000135906
AL840638.2

chr5_+_41477954 0.07 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr6_-_39080630 0.06 ENSDART00000021520
ENSDART00000128308
eif4bb
eukaryotic translation initiation factor 4Bb
chr1_+_44582369 0.06 ENSDART00000003022
ENSDART00000137980
med19b
mediator complex subunit 19b
chr3_-_34136368 0.06 ENSDART00000136900
ENSDART00000186125
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr4_+_55055395 0.06 ENSDART00000159142
ENSDART00000099760
si:dkey-19c16.12
si:dkey-19c16.12
chr24_+_3478871 0.06 ENSDART00000111491
ENSDART00000134598
ENSDART00000142407
wdr37
WD repeat domain 37
chr5_+_61862199 0.06 ENSDART00000132452
sympk
symplekin
chr12_+_6465557 0.06 ENSDART00000066477
ENSDART00000122271
dkk1b
dickkopf WNT signaling pathway inhibitor 1b
chr3_-_34107685 0.06 ENSDART00000151130
ighv4-3
immunoglobulin heavy variable 4-3
chr5_+_47863153 0.06 ENSDART00000051518
rasa1a
RAS p21 protein activator (GTPase activating protein) 1a
chr9_-_41090048 0.06 ENSDART00000131681
ENSDART00000182552
asnsd1
asparagine synthetase domain containing 1
chr17_+_27456804 0.06 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
ctsl.1
cathepsin L.1
chr15_+_25528290 0.06 ENSDART00000123143
npat
nuclear protein, ataxia-telangiectasia locus
chr18_+_3169579 0.06 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr8_-_21052371 0.06 ENSDART00000136561
si:dkeyp-82a1.6
si:dkeyp-82a1.6
chr17_+_37253706 0.06 ENSDART00000076004
tmem62
transmembrane protein 62
chr15_-_43284021 0.06 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr5_-_25084318 0.06 ENSDART00000089339
dph7
diphthamide biosynthesis 7
chr25_-_34280080 0.06 ENSDART00000085251
gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr24_+_36392040 0.06 ENSDART00000136057
arf2b
ADP-ribosylation factor 2b
chr3_-_27066451 0.06 ENSDART00000156228
ENSDART00000156311
atf7ip2
activating transcription factor 7 interacting protein 2
chr1_-_44048798 0.06 ENSDART00000073746
si:ch73-109d9.2
si:ch73-109d9.2
chr6_+_50451337 0.06 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr17_+_8754426 0.06 ENSDART00000185519
edrf1
erythroid differentiation regulatory factor 1
chr18_-_18584839 0.06 ENSDART00000159274
sf3b3
splicing factor 3b, subunit 3
chr3_-_3413669 0.06 ENSDART00000113517
ENSDART00000179861
ENSDART00000115331
zgc:171446
zgc:171446
chr5_+_51833132 0.06 ENSDART00000167491
papd4
PAP associated domain containing 4
chr19_-_27006764 0.06 ENSDART00000089540
sacm1la
SAC1 like phosphatidylinositide phosphatase a
chr24_+_36392486 0.06 ENSDART00000007381
ENSDART00000135898
arf2b
ADP-ribosylation factor 2b
chr5_+_64397454 0.06 ENSDART00000015940
edf1
endothelial differentiation-related factor 1
chr19_-_1855368 0.06 ENSDART00000029646
rplp1
ribosomal protein, large, P1
chr16_+_11029762 0.06 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr18_+_38755023 0.06 ENSDART00000010177
ENSDART00000193136
onecut1
one cut homeobox 1
chr12_+_22823219 0.06 ENSDART00000153199
ENSDART00000192571
afap1
actin filament associated protein 1
chr2_+_44571200 0.06 ENSDART00000098132
klhl24a
kelch-like family member 24a
chr14_-_45558490 0.06 ENSDART00000165060
ints5
integrator complex subunit 5
chr8_-_1266181 0.06 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B

Network of associatons between targets according to the STRING database.

First level regulatory network of SPDEF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.1 0.2 GO:0019264 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.2 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.1 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.1 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.0 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.1 GO:0097201 response to acidic pH(GO:0010447) negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.2 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529)
0.0 0.0 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.0 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0061011 hepatic duct development(GO:0061011)
0.0 0.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:1903826 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.0 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.0 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0051219 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components