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PRJNA207719: Tissue specific transcriptome profiling

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Results for alx1

Z-value: 1.09

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Transcription factors associated with alx1

Gene Symbol Gene ID Gene Info
alx1
ENSDARG00000062824 ALX homeobox 1
alx1
ENSDARG00000110530 ALX homeobox 1
alx1
ENSDARG00000115230 ALX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
alx1dr11_v1_chr18_+_16246806_16246806-0.128.5e-01Click!

Activity profile of alx1 motif

Sorted Z-values of alx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31276842 1.80 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr15_-_21877726 0.76 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr20_-_40755614 0.65 ENSDART00000061247
cx32.3
connexin 32.3
chr9_-_22821901 0.57 ENSDART00000101711
neb
nebulin
chr10_+_21867307 0.55 ENSDART00000126629
cbln17
cerebellin 17
chr9_-_22834860 0.48 ENSDART00000146486
neb
nebulin
chr7_-_38792543 0.46 ENSDART00000157416
si:dkey-23n7.10
si:dkey-23n7.10
chr25_+_31267268 0.45 ENSDART00000181239
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr24_-_40744672 0.43 ENSDART00000160672
CU633479.1

chr25_+_31277415 0.43 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr9_-_22822084 0.42 ENSDART00000142020
neb
nebulin
chr22_-_24818066 0.42 ENSDART00000143443
vtg6
vitellogenin 6
chr6_+_23887314 0.40 ENSDART00000163188
znf648
zinc finger protein 648
chr3_+_12816362 0.39 ENSDART00000163743
ENSDART00000170788
cyp2k6
cytochrome P450, family 2, subfamily K, polypeptide 6
chr21_-_22737228 0.39 ENSDART00000151366
fbxo40.2
F-box protein 40, tandem duplicate 2
chr16_+_26777473 0.38 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr5_+_44805269 0.38 ENSDART00000136965
ctsla
cathepsin La
chr13_-_20381485 0.36 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr24_-_38110779 0.35 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr18_+_14564085 0.35 ENSDART00000009363
ENSDART00000141813
ENSDART00000136120
si:dkey-246g23.4
si:dkey-246g23.4
chr19_-_42556086 0.35 ENSDART00000051731
si:dkey-267n13.1
si:dkey-267n13.1
chr2_-_1514001 0.33 ENSDART00000057736
c8b
complement component 8, beta polypeptide
chr21_-_23331619 0.33 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr10_+_6884123 0.32 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr6_-_53426773 0.32 ENSDART00000162791
mst1
macrophage stimulating 1
chr5_-_23280098 0.32 ENSDART00000126540
ENSDART00000051533
plp1b
proteolipid protein 1b
chr23_-_27571667 0.31 ENSDART00000008174
pfkma
phosphofructokinase, muscle a
chr9_-_49493305 0.31 ENSDART00000148707
ENSDART00000148561
xirp2b
xin actin binding repeat containing 2b
chr25_+_3327071 0.31 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr13_-_50108337 0.30 ENSDART00000133308
nid1a
nidogen 1a
chr20_-_23426339 0.30 ENSDART00000004625
zar1
zygote arrest 1
chr15_-_2493771 0.30 ENSDART00000184906
neu4
sialidase 4
chr10_+_6884627 0.30 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr18_+_15644559 0.29 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr14_+_22113331 0.29 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr6_+_55032439 0.29 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
mybphb
myosin binding protein Hb
chr5_+_37903790 0.28 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr19_+_15441022 0.28 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr15_-_2519640 0.27 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr13_+_2338761 0.27 ENSDART00000102791
ENSDART00000129911
klhl31
kelch-like family member 31
chr2_-_30324610 0.27 ENSDART00000185422
jph1b
junctophilin 1b
chr2_-_15324837 0.26 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr5_+_28857969 0.26 ENSDART00000149850
si:ch211-186e20.2
si:ch211-186e20.2
chr18_+_8320165 0.26 ENSDART00000092053
chkb
choline kinase beta
chr13_+_38817871 0.26 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr8_+_45334255 0.25 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr7_+_20471315 0.25 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr10_+_43994471 0.24 ENSDART00000138242
ENSDART00000186359
cldn5b
claudin 5b
chr12_-_14143344 0.24 ENSDART00000152742
buc2l
bucky ball 2-like
chr2_-_30324297 0.24 ENSDART00000099078
jph1b
junctophilin 1b
chr22_-_23612854 0.24 ENSDART00000165885
cfhl5
complement factor H like 5
chr5_+_51594209 0.24 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr16_-_17197546 0.23 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr10_-_7756865 0.23 ENSDART00000114373
ENSDART00000125407
ENSDART00000016317
loxa
lysyl oxidase a
chr22_+_16555939 0.23 ENSDART00000012604
pdzk1ip1
PDZK1 interacting protein 1
chr23_-_32157865 0.22 ENSDART00000000876
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr1_+_17695426 0.22 ENSDART00000103236
ankrd37
ankyrin repeat domain 37
chr16_-_28658341 0.22 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr9_+_29548195 0.22 ENSDART00000176057
rnf17
ring finger protein 17
chr3_+_17537352 0.22 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr7_-_27685365 0.21 ENSDART00000188342
calca
calcitonin/calcitonin-related polypeptide, alpha
chr7_-_51773166 0.21 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr5_+_19314574 0.21 ENSDART00000133247
rusc2
RUN and SH3 domain containing 2
chr24_+_33392698 0.21 ENSDART00000122579
si:ch73-173p19.1
si:ch73-173p19.1
chr10_-_21362071 0.21 ENSDART00000125167
avd
avidin
chr24_+_17270129 0.20 ENSDART00000186729
spag6
sperm associated antigen 6
chr2_-_37098785 0.20 ENSDART00000003670
zgc:101744
zgc:101744
chr16_-_16761164 0.20 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr15_-_20939579 0.20 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr2_-_51794472 0.20 ENSDART00000186652
BX908782.3

chr5_-_56416188 0.20 ENSDART00000146773
acaca
acetyl-CoA carboxylase alpha
chr22_+_18477934 0.20 ENSDART00000132684
cilp2
cartilage intermediate layer protein 2
chr9_+_8396755 0.20 ENSDART00000043067
zgc:171776
zgc:171776
chr19_-_657439 0.19 ENSDART00000167100
slc6a18
solute carrier family 6 (neutral amino acid transporter), member 18
chr22_-_10586191 0.19 ENSDART00000148418
si:dkey-42i9.16
si:dkey-42i9.16
chr10_-_21362320 0.19 ENSDART00000189789
avd
avidin
chr3_-_15080226 0.19 ENSDART00000109818
ENSDART00000139835
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr19_-_42571829 0.18 ENSDART00000102606
zgc:103438
zgc:103438
chr23_+_40460333 0.18 ENSDART00000184658
soga3b
SOGA family member 3b
chr20_-_7583486 0.18 ENSDART00000144729
usp24
ubiquitin specific peptidase 24
chr7_-_34473389 0.18 ENSDART00000160532
si:zfos-1897c11.1
si:zfos-1897c11.1
chr13_+_35637048 0.18 ENSDART00000085037
thbs2a
thrombospondin 2a
chr22_-_10459880 0.18 ENSDART00000064801
ogn
osteoglycin
chr19_+_15440841 0.18 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr25_+_3306620 0.18 ENSDART00000182085
ENSDART00000034704
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr21_-_23110841 0.18 ENSDART00000147896
ENSDART00000003076
ENSDART00000184925
ENSDART00000190386
usp28
ubiquitin specific peptidase 28
chr23_-_32162810 0.18 ENSDART00000155905
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr18_-_16801033 0.17 ENSDART00000100100
admb
adrenomedullin b
chr24_-_3783497 0.17 ENSDART00000158354
adarb2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr2_+_6253246 0.17 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr23_+_41679586 0.17 ENSDART00000067662
CU914487.1

chr1_+_24387659 0.17 ENSDART00000130356
qdprb2
quinoid dihydropteridine reductase b2
chr19_-_20403845 0.17 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr5_+_64732036 0.17 ENSDART00000073950
olfm1a
olfactomedin 1a
chr13_-_10945288 0.16 ENSDART00000114315
ENSDART00000164667
ENSDART00000159482
abcg8
ATP-binding cassette, sub-family G (WHITE), member 8
chr14_+_36521005 0.16 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr7_-_31759602 0.16 ENSDART00000113467
igdcc4
immunoglobulin superfamily, DCC subclass, member 4
chr9_-_19161982 0.16 ENSDART00000081878
pou1f1
POU class 1 homeobox 1
chr22_-_20924564 0.16 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr16_-_29387215 0.16 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr17_+_52612866 0.16 ENSDART00000182828
ENSDART00000191156
ENSDART00000188814
ENSDART00000109891
angel1
angel homolog 1 (Drosophila)
chr19_+_7152966 0.16 ENSDART00000080348
brd2a
bromodomain containing 2a
chr15_-_16098531 0.15 ENSDART00000080377
aldoca
aldolase C, fructose-bisphosphate, a
chr8_+_25034544 0.15 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr1_-_12109216 0.15 ENSDART00000079930
mttp
microsomal triglyceride transfer protein
chr13_+_38990939 0.15 ENSDART00000145979
col19a1
collagen, type XIX, alpha 1
chr10_-_25217347 0.15 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr9_-_31278048 0.15 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr5_-_56412262 0.15 ENSDART00000083079
acaca
acetyl-CoA carboxylase alpha
chr6_-_46861676 0.15 ENSDART00000188712
ENSDART00000190148
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr5_-_9216758 0.15 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr24_+_12835935 0.14 ENSDART00000114762
nanog
nanog homeobox
chr6_+_6828167 0.14 ENSDART00000181284
si:ch211-85n16.4
si:ch211-85n16.4
chr20_+_38032143 0.14 ENSDART00000032161
galnt14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr23_+_24272421 0.14 ENSDART00000029974
clcnk
chloride channel K
chr10_-_26744131 0.14 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr17_-_23416897 0.14 ENSDART00000163391
si:ch211-149k12.3
si:ch211-149k12.3
chr1_-_9249943 0.14 ENSDART00000055011
zgc:136472
zgc:136472
chr17_+_46818521 0.14 ENSDART00000156022
pimr14
Pim proto-oncogene, serine/threonine kinase, related 14
chr1_-_55068941 0.14 ENSDART00000152143
ENSDART00000152590
peli1a
pellino E3 ubiquitin protein ligase 1a
chr1_-_513762 0.14 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr16_-_42056137 0.14 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr6_+_41191482 0.14 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr6_+_8626427 0.14 ENSDART00000193660
tspeara
thrombospondin-type laminin G domain and EAR repeats a
chr25_-_25384045 0.14 ENSDART00000150631
zgc:123278
zgc:123278
chr7_-_31759394 0.14 ENSDART00000193040
igdcc4
immunoglobulin superfamily, DCC subclass, member 4
chr9_+_21146862 0.14 ENSDART00000136365
hao2
hydroxyacid oxidase 2 (long chain)
chr17_+_21295132 0.14 ENSDART00000103845
eno4
enolase family member 4
chr16_+_40563533 0.13 ENSDART00000190368
tp53inp1
tumor protein p53 inducible nuclear protein 1
chr20_+_32118559 0.13 ENSDART00000026273
cd164
CD164 molecule, sialomucin
chr24_+_7336411 0.13 ENSDART00000191170
kmt2ca
lysine (K)-specific methyltransferase 2Ca
chr24_-_21914276 0.13 ENSDART00000128687
c1qtnf9
C1q and TNF related 9
chr11_-_41853874 0.13 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr15_-_34458495 0.13 ENSDART00000059954
meox2a
mesenchyme homeobox 2a
chr24_-_29963858 0.13 ENSDART00000183442
CR352310.1

chr1_-_44812014 0.13 ENSDART00000139044
si:dkey-9i23.8
si:dkey-9i23.8
chr24_+_21540842 0.13 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr8_-_28449782 0.13 ENSDART00000062702
cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr16_+_39159752 0.13 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr14_-_12307522 0.13 ENSDART00000163900
myot
myotilin
chr14_+_44794936 0.13 ENSDART00000128881
zgc:195212
zgc:195212
chr15_+_34988148 0.13 ENSDART00000076269
ccdc105
coiled-coil domain containing 105
chr15_-_4969525 0.13 ENSDART00000157223
lipt2
lipoyl(octanoyl) transferase 2
chr8_+_635704 0.12 ENSDART00000130358
csgalnact1b
chondroitin sulfate N-acetylgalactosaminyltransferase 1b
chr12_-_30359498 0.12 ENSDART00000152981
ENSDART00000189988
tdrd1
tudor domain containing 1
chr16_+_27349585 0.12 ENSDART00000142573
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr9_-_50001606 0.12 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr9_+_50001746 0.12 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr8_+_3820134 0.12 ENSDART00000122454
citb
citron rho-interacting serine/threonine kinase b
chr14_-_2933185 0.12 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr20_+_46925581 0.12 ENSDART00000192531
si:ch73-21k16.5
si:ch73-21k16.5
chr21_-_35419486 0.12 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr24_+_26895748 0.12 ENSDART00000089351
nceh1b.1
neutral cholesterol ester hydrolase 1b, tandem duplicate 1
chr6_+_9204099 0.12 ENSDART00000150167
ENSDART00000115394
tbx19
T-box 19
chr16_-_46579936 0.12 ENSDART00000166143
ENSDART00000127212
si:dkey-152b24.6
si:dkey-152b24.6
chr23_-_17003533 0.12 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr7_+_73397283 0.12 ENSDART00000174390
CABZ01081780.1

chr8_+_41037541 0.12 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr15_+_31344472 0.12 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
or107-1
odorant receptor, family D, subfamily 107, member 1
chr18_+_38807239 0.12 ENSDART00000184332
fam214a
family with sequence similarity 214, member A
chr12_-_30359031 0.11 ENSDART00000192628
tdrd1
tudor domain containing 1
chr17_-_29119362 0.11 ENSDART00000104204
foxg1a
forkhead box G1a
chr4_-_14315855 0.11 ENSDART00000133325
nell2b
neural EGFL like 2b
chr22_+_1170294 0.11 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr2_+_25198648 0.11 ENSDART00000110922
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr5_+_35786141 0.11 ENSDART00000022043
ENSDART00000127383
stard8
StAR-related lipid transfer (START) domain containing 8
chr9_+_23224761 0.11 ENSDART00000142008
map3k19
mitogen-activated protein kinase kinase kinase 19
chr2_+_37227011 0.11 ENSDART00000126587
ENSDART00000084958
samd7
sterile alpha motif domain containing 7
chr8_-_45838277 0.11 ENSDART00000046064
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr19_+_46158078 0.11 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr22_-_8725768 0.11 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
si:ch73-27e22.1
si:ch73-27e22.8
chr8_-_46525092 0.11 ENSDART00000030482
sult1st2
sulfotransferase family 1, cytosolic sulfotransferase 2
chr15_-_22074315 0.11 ENSDART00000149830
drd2a
dopamine receptor D2a
chr11_-_1550709 0.11 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr4_+_14900042 0.11 ENSDART00000018261
akr1b1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr14_+_34492288 0.11 ENSDART00000144301
wnt8a
wingless-type MMTV integration site family, member 8a
chr23_-_30954738 0.11 ENSDART00000188996
osbpl2a
oxysterol binding protein-like 2a
chr20_-_7582936 0.11 ENSDART00000083890
usp24
ubiquitin specific peptidase 24
chr1_-_55248496 0.11 ENSDART00000098615
nanos3
nanos homolog 3
chr4_-_20292821 0.11 ENSDART00000136069
ENSDART00000192504
cacna2d4a
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr21_+_43404945 0.11 ENSDART00000142234
frmd7
FERM domain containing 7
chr9_+_29548630 0.11 ENSDART00000132295
rnf17
ring finger protein 17
chr24_+_5208171 0.11 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
si:ch73-206p6.1
chr4_+_12612723 0.11 ENSDART00000133767
lmo3
LIM domain only 3
chr20_+_4060839 0.11 ENSDART00000178565
TRIM67
tripartite motif containing 67
chr12_+_48803098 0.10 ENSDART00000074768
ppifb
peptidylprolyl isomerase Fb
chr6_+_16736871 0.10 ENSDART00000155471
pimr12
Pim proto-oncogene, serine/threonine kinase, related 12
chr22_-_10486477 0.10 ENSDART00000184366
aspn
asporin (LRR class 1)
chr6_+_9870192 0.10 ENSDART00000150894
MPP4 (1 of many)
si:ch211-222n4.6
chr17_+_23298928 0.10 ENSDART00000153652
zgc:165461
zgc:165461
chr9_+_34641237 0.10 ENSDART00000133996
shox
short stature homeobox
chr5_-_39698224 0.10 ENSDART00000076929
prkg2
protein kinase, cGMP-dependent, type II
chr24_-_25166720 0.10 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr24_+_2495197 0.10 ENSDART00000146887
f13a1a.1
coagulation factor XIII, A1 polypeptide a, tandem duplicate 1
chr20_-_16171297 0.10 ENSDART00000012476
coa7
cytochrome c oxidase assembly factor 7
chr2_+_58221163 0.10 ENSDART00000157939
FO704813.1

chr5_+_57924611 0.10 ENSDART00000050949
btg4
B-cell translocation gene 4
chr8_+_20825987 0.10 ENSDART00000133309
si:ch211-133l5.4
si:ch211-133l5.4
chr24_-_31452875 0.10 ENSDART00000187381
ENSDART00000185128
cngb3.2
cyclic nucleotide gated channel beta 3, tandem duplicate 2
chr1_-_29139141 0.10 ENSDART00000075546
ENSDART00000133246
hsf2bp
heat shock transcription factor 2 binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of alx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.2 0.8 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.1 0.4 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.3 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.5 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.2 GO:0042755 eating behavior(GO:0042755)
0.1 0.2 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 0.2 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.0 2.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.0 0.4 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.2 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.6 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.1 GO:0060074 synapse maturation(GO:0060074)
0.0 0.2 GO:0065005 plasma lipoprotein particle assembly(GO:0034377) protein-lipid complex assembly(GO:0065005)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.3 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.0 0.3 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0010658 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.4 GO:0060046 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.4 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.3 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.2 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 0.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.0 0.1 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0032355 response to estradiol(GO:0032355)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755) protein homotrimerization(GO:0070207)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.0 GO:0035095 behavioral response to nicotine(GO:0035095)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.8 GO:0042627 chylomicron(GO:0042627)
0.1 2.3 GO:0005861 troponin complex(GO:0005861)
0.1 0.2 GO:0097189 apoptotic body(GO:0097189)
0.0 0.4 GO:0071546 pi-body(GO:0071546)
0.0 0.8 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 0.0 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.4 GO:0009374 biotin binding(GO:0009374)
0.1 0.2 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.4 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.0 0.3 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.0 0.2 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 0.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.0 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE