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PRJNA207719: Tissue specific transcriptome profiling

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Results for alx4a+alx4b

Z-value: 0.65

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Transcription factors associated with alx4a+alx4b

Gene Symbol Gene ID Gene Info
alx4b
ENSDARG00000074442 ALX homeobox 4b
alx4a
ENSDARG00000088332 ALX homeobox 4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
alx4bdr11_v1_chr18_+_38321039_38321039-0.395.2e-01Click!
alx4adr11_v1_chr7_-_26924903_269249030.326.0e-01Click!

Activity profile of alx4a+alx4b motif

Sorted Z-values of alx4a+alx4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_9669717 0.73 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr17_-_12336987 0.68 ENSDART00000172001
snap25b
synaptosomal-associated protein, 25b
chr5_-_23280098 0.62 ENSDART00000126540
ENSDART00000051533
plp1b
proteolipid protein 1b
chr2_+_50608099 0.51 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr12_+_18578597 0.51 ENSDART00000134944
grid2ipb
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr8_+_7359294 0.49 ENSDART00000121708
pcsk1nl
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr23_-_3681026 0.48 ENSDART00000192128
ENSDART00000040086
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr4_+_21129752 0.47 ENSDART00000169764
syt1a
synaptotagmin Ia
chr2_-_38000276 0.46 ENSDART00000034790
pcp4l1
Purkinje cell protein 4 like 1
chr18_+_21408794 0.44 ENSDART00000140161
necab2
N-terminal EF-hand calcium binding protein 2
chr3_+_24361096 0.44 ENSDART00000132387
pvalb6
parvalbumin 6
chr17_+_15433671 0.43 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr11_+_30057762 0.42 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr16_-_28856112 0.41 ENSDART00000078543
syt11b
synaptotagmin XIb
chr17_+_15433518 0.40 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr16_-_12173399 0.39 ENSDART00000142574
clstn3
calsyntenin 3
chr21_+_28958471 0.39 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr19_-_9867001 0.39 ENSDART00000091695
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr19_-_20113696 0.39 ENSDART00000188813
npy
neuropeptide Y
chr20_-_29864390 0.38 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr11_-_1509773 0.38 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr14_-_34276574 0.37 ENSDART00000021437
gria1a
glutamate receptor, ionotropic, AMPA 1a
chr7_+_39634873 0.36 ENSDART00000114774
ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr9_-_35334642 0.36 ENSDART00000157195
ncam2
neural cell adhesion molecule 2
chr21_+_31150773 0.36 ENSDART00000126205
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr15_-_44601331 0.36 ENSDART00000161514
zgc:165508
zgc:165508
chr16_-_12173554 0.35 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr19_-_26869103 0.35 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr8_+_49778486 0.35 ENSDART00000131732
ntrk2a
neurotrophic tyrosine kinase, receptor, type 2a
chr11_-_2131280 0.35 ENSDART00000008409
calcoco1b
calcium binding and coiled-coil domain 1b
chr21_+_31150438 0.35 ENSDART00000065366
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr5_+_64739762 0.35 ENSDART00000161112
ENSDART00000135610
ENSDART00000002908
olfm1a
olfactomedin 1a
chr6_+_27151940 0.34 ENSDART00000088364
kif1aa
kinesin family member 1Aa
chr15_-_33925851 0.34 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr6_-_11768198 0.33 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr8_-_4596662 0.33 ENSDART00000138199
sept5a
septin 5a
chr8_+_49778756 0.32 ENSDART00000083790
ntrk2a
neurotrophic tyrosine kinase, receptor, type 2a
chr6_-_40029423 0.32 ENSDART00000103230
pfkfb4b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr17_-_200316 0.32 ENSDART00000190561
CABZ01083778.1

chr3_-_58543658 0.32 ENSDART00000042386
unm_sa1261
un-named sa1261
chr14_-_49063157 0.32 ENSDART00000021260
sept8b
septin 8b
chr9_+_54039006 0.31 ENSDART00000112441
tlr7
toll-like receptor 7
chr20_+_19512727 0.30 ENSDART00000063696
atraid
all-trans retinoic acid-induced differentiation factor
chr10_-_27049170 0.30 ENSDART00000143451
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr13_-_29420885 0.30 ENSDART00000024225
chata
choline O-acetyltransferase a
chr16_+_34531486 0.30 ENSDART00000043291
paqr7b
progestin and adipoQ receptor family member VII, b
chr25_-_19420949 0.30 ENSDART00000181338
map1ab
microtubule-associated protein 1Ab
chr5_-_40190949 0.29 ENSDART00000175588
wdfy3
WD repeat and FYVE domain containing 3
chr3_+_62000822 0.29 ENSDART00000106680
rai1
retinoic acid induced 1
chr14_-_4556896 0.29 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr22_-_20011476 0.29 ENSDART00000093312
ENSDART00000093310
celf5a
cugbp, Elav-like family member 5a
chr6_+_3004972 0.29 ENSDART00000186750
ENSDART00000183862
ENSDART00000191485
ENSDART00000171014
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr18_+_2837563 0.29 ENSDART00000171495
ENSDART00000160228
fam168a
family with sequence similarity 168, member A
chr24_-_7697274 0.29 ENSDART00000186077
syt5b
synaptotagmin Vb
chr25_+_126174 0.29 ENSDART00000168913
cntn1a
contactin 1a
chr13_-_11644806 0.28 ENSDART00000169953
dctn1b
dynactin 1b
chr9_-_43538328 0.28 ENSDART00000140526
znf385b
zinc finger protein 385B
chr23_+_16638639 0.27 ENSDART00000143545
snphb
syntaphilin b
chr24_+_41940299 0.27 ENSDART00000022349
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr10_-_2524297 0.26 ENSDART00000192475
CU856539.1

chr6_+_3166941 0.26 ENSDART00000168912
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr8_+_6863462 0.26 ENSDART00000064163
nefmb
neurofilament, medium polypeptide b
chr3_-_6519691 0.25 ENSDART00000165273
ENSDART00000179882
ENSDART00000172292
GGA3 (1 of many)
si:ch73-157i16.3
chr9_+_2574122 0.25 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr19_-_15397946 0.25 ENSDART00000143480
hivep3a
human immunodeficiency virus type I enhancer binding protein 3a
chr3_-_21280373 0.25 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr2_+_53204750 0.25 ENSDART00000163644
zgc:165603
zgc:165603
chr3_-_32818607 0.25 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr15_-_9272328 0.25 ENSDART00000172114
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr6_-_39489190 0.25 ENSDART00000151299
scn8ab
sodium channel, voltage gated, type VIII, alpha subunit b
chr21_-_20939488 0.24 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr12_+_31735159 0.24 ENSDART00000185442
RNF157
si:dkey-49c17.3
chr6_-_46941245 0.24 ENSDART00000037875
igfn1.1
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 1
chr8_+_36500061 0.24 ENSDART00000185840
slc7a4
solute carrier family 7, member 4
chr25_-_12902242 0.24 ENSDART00000164733
sept15
septin 15
chr17_-_36896560 0.23 ENSDART00000045287
mapre3a
microtubule-associated protein, RP/EB family, member 3a
chr10_-_2524917 0.23 ENSDART00000188642
CU856539.1

chr17_-_3190070 0.23 ENSDART00000115027
tmem151bb
transmembrane protein 151Bb
chr25_-_13569234 0.23 ENSDART00000189645
fa2h
fatty acid 2-hydroxylase
chr19_+_5480327 0.23 ENSDART00000148794
jupb
junction plakoglobin b
chr14_+_22591624 0.23 ENSDART00000108987
gfra4b
GDNF family receptor alpha 4b
chr22_+_17828267 0.23 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr7_-_72261721 0.23 ENSDART00000172229
RASGRP2
RAS guanyl releasing protein 2
chr11_+_41242644 0.23 ENSDART00000172008
pax7a
paired box 7a
chr7_+_23515966 0.22 ENSDART00000186893
ENSDART00000186189
zgc:109889
zgc:109889
chr4_-_1801519 0.22 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr9_-_1703761 0.22 ENSDART00000144822
ENSDART00000137210
ENSDART00000135273
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr20_+_3108597 0.22 ENSDART00000133435
CEP170B (1 of many)
si:ch73-212j7.1
chr7_+_34620418 0.22 ENSDART00000081338
slc9a5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr20_+_66857 0.22 ENSDART00000114999
lrfn2b
leucine rich repeat and fibronectin type III domain containing 2b
chr21_-_13123176 0.22 ENSDART00000144866
ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr3_-_23407720 0.21 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr25_+_5821910 0.21 ENSDART00000161035
C12orf75
chromosome 12 open reading frame 75
chr16_+_2820340 0.21 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr23_+_44741500 0.21 ENSDART00000166421
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr15_+_46108548 0.21 ENSDART00000099023
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr22_-_13466246 0.20 ENSDART00000134035
cntnap5b
contactin associated protein-like 5b
chr9_+_29643036 0.20 ENSDART00000023210
ENSDART00000175160
trim13
tripartite motif containing 13
chr2_+_55916911 0.20 ENSDART00000189483
ENSDART00000183647
ENSDART00000083470
atcayb
ataxia, cerebellar, Cayman type b
chr21_+_27513859 0.20 ENSDART00000065420
pacs1a
phosphofurin acidic cluster sorting protein 1a
chr5_+_59392183 0.20 ENSDART00000082983
ENSDART00000180882
clip2
CAP-GLY domain containing linker protein 2
chr5_+_37903790 0.19 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr21_+_21195487 0.19 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr16_-_41004731 0.19 ENSDART00000102591
KCNV1
si:dkey-201i6.2
chr6_+_35362225 0.19 ENSDART00000133783
ENSDART00000102483
rgs4
regulator of G protein signaling 4
chr6_-_46053300 0.19 ENSDART00000169722
ca16b
carbonic anhydrase XVI b
chr7_+_46368520 0.19 ENSDART00000192821
znf536
zinc finger protein 536
chr12_-_31794908 0.19 ENSDART00000105583
ENSDART00000153449
nat9
N-acetyltransferase 9 (GCN5-related, putative)
chr3_+_33341640 0.19 ENSDART00000186352
pyya
peptide YYa
chr9_-_14504834 0.19 ENSDART00000056103
nrp2b
neuropilin 2b
chr3_+_32443395 0.19 ENSDART00000188447
prr12b
proline rich 12b
chr5_-_41494831 0.18 ENSDART00000051081
eef2l2
eukaryotic translation elongation factor 2, like 2
chr4_-_2219705 0.18 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr25_+_22719852 0.18 ENSDART00000088422
abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr2_-_30668580 0.18 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr5_+_4054704 0.18 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr19_-_25149598 0.18 ENSDART00000162917
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr25_-_27722614 0.18 ENSDART00000190154
zgc:153935
zgc:153935
chr20_+_32552912 0.17 ENSDART00000009691
scml4
Scm polycomb group protein like 4
chr14_+_24284756 0.17 ENSDART00000079164
klhl3
kelch-like family member 3
chr25_-_25058508 0.17 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr18_+_24919614 0.17 ENSDART00000008638
rgma
repulsive guidance molecule family member a
chr8_+_29742237 0.17 ENSDART00000133955
ENSDART00000020621
mapk4
mitogen-activated protein kinase 4
chr23_-_16692312 0.17 ENSDART00000046784
fkbp1ab
FK506 binding protein 1Ab
chr8_-_30979494 0.17 ENSDART00000138959
si:ch211-251j10.3
si:ch211-251j10.3
chr21_+_33503835 0.17 ENSDART00000125658
clint1b
clathrin interactor 1b
chr10_+_15255198 0.17 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr20_+_591505 0.17 ENSDART00000046438
kcnk2b
potassium channel, subfamily K, member 2b
chr24_+_5912898 0.17 ENSDART00000132686
pimr63
Pim proto-oncogene, serine/threonine kinase, related 63
chr4_+_9400012 0.17 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr16_-_32837806 0.16 ENSDART00000003997
MCHR2
si:dkey-165n16.5
chr15_-_20939579 0.16 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr14_-_25078569 0.16 ENSDART00000172802
ENSDART00000173345
ENSDART00000135004
matr3l1.1
matrin 3-like 1.1
chr12_+_47698356 0.16 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr17_-_21418340 0.16 ENSDART00000007021
atp6v1ba
ATPase, H+ transporting, lysosomal, V1 subunit B, member a
chr15_-_22074315 0.16 ENSDART00000149830
drd2a
dopamine receptor D2a
chr4_+_3980247 0.16 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr5_-_66397688 0.16 ENSDART00000161483
hip1rb
huntingtin interacting protein 1 related b
chr13_+_29773153 0.16 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
pax2a
paired box 2a
chr25_+_31276842 0.16 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr24_+_5912635 0.16 ENSDART00000153736
pimr63
Pim proto-oncogene, serine/threonine kinase, related 63
chr15_-_30505607 0.16 ENSDART00000155212
msi2b
musashi RNA-binding protein 2b
chr13_-_18695289 0.16 ENSDART00000176809
sfxn3
sideroflexin 3
chr4_-_5019113 0.15 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr23_-_333457 0.15 ENSDART00000114486
uhrf1bp1
UHRF1 binding protein 1
chr8_-_12264486 0.15 ENSDART00000091612
ENSDART00000135812
dab2ipa
DAB2 interacting protein a
chr10_+_25219728 0.15 ENSDART00000193829
grm5a
glutamate receptor, metabotropic 5a
chr25_+_29161609 0.15 ENSDART00000180752
pkmb
pyruvate kinase M1/2b
chr15_-_19051152 0.15 ENSDART00000186453
arhgap32a
Rho GTPase activating protein 32a
chr3_+_5575313 0.15 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
si:ch211-106h11.3
chr1_+_6172786 0.15 ENSDART00000126468
prkag3a
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr5_+_21144269 0.15 ENSDART00000028087
cds2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr22_-_12160283 0.15 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr8_+_17775247 0.14 ENSDART00000112356
si:ch211-150o23.3
si:ch211-150o23.3
chr10_+_42423318 0.14 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr1_+_59293873 0.14 ENSDART00000168036
rdh8b
retinol dehydrogenase 8b
chr6_+_11249706 0.14 ENSDART00000186547
ENSDART00000193287
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr25_-_13490744 0.14 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr1_-_50438247 0.14 ENSDART00000114098
dkk2
dickkopf WNT signaling pathway inhibitor 2
chr10_-_5581487 0.14 ENSDART00000141943
syk
spleen tyrosine kinase
chr5_+_24156170 0.14 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr1_-_46981134 0.14 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr15_-_25527580 0.14 ENSDART00000167005
ENSDART00000157498
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr3_-_6767956 0.14 ENSDART00000192556
mast1b
microtubule associated serine/threonine kinase 1b
chr5_+_7279104 0.14 ENSDART00000190014
si:ch73-72b7.1
si:ch73-72b7.1
chr21_+_13387965 0.14 ENSDART00000134347
zgc:113162
zgc:113162
chr8_+_27807266 0.14 ENSDART00000170037
capza1b
capping protein (actin filament) muscle Z-line, alpha 1b
chr13_+_7292061 0.13 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr5_+_1109098 0.13 ENSDART00000166268
LO017790.1

chr5_-_55933420 0.13 ENSDART00000050966
slc25a46
solute carrier family 25, member 46
chr9_-_32177117 0.13 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr14_+_45406299 0.13 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr13_+_6342410 0.13 ENSDART00000065228
csmd1a
CUB and Sushi multiple domains 1a
chr22_-_16443199 0.13 ENSDART00000006290
ENSDART00000193335
plekhb2
pleckstrin homology domain containing, family B (evectins) member 2
chr7_-_71829649 0.13 ENSDART00000160449
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr5_-_12219572 0.13 ENSDART00000167834
nos1
nitric oxide synthase 1 (neuronal)
chr3_+_13637383 0.13 ENSDART00000166000
si:ch211-194b1.1
si:ch211-194b1.1
chr17_+_41992054 0.13 ENSDART00000182878
ENSDART00000111537
kiz
kizuna centrosomal protein
chr1_-_15797663 0.13 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr14_+_29550323 0.13 ENSDART00000157943
TENM2
si:dkey-34l15.2
chr14_+_8940326 0.12 ENSDART00000159920
rps6kal
ribosomal protein S6 kinase a, like
chr8_+_36503797 0.12 ENSDART00000184785
slc7a4
solute carrier family 7, member 4
chr16_-_28658341 0.12 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr19_+_5291935 0.12 ENSDART00000141237
si:dkeyp-113d7.10
si:dkeyp-113d7.10
chr20_-_28404362 0.12 ENSDART00000055932
ENSDART00000188161
pigh
phosphatidylinositol glycan anchor biosynthesis, class H
chr6_+_11250033 0.12 ENSDART00000065411
ENSDART00000132677
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr25_-_6432463 0.12 ENSDART00000110389
ptpn9a
protein tyrosine phosphatase, non-receptor type 9, a
chr16_+_13818500 0.12 ENSDART00000135245
flcn
folliculin
chr2_+_2223837 0.12 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr4_+_16885854 0.12 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr12_-_41662327 0.12 ENSDART00000191602
ENSDART00000170423
jakmip3
Janus kinase and microtubule interacting protein 3
chr24_-_5911973 0.12 ENSDART00000077933
ENSDART00000077922
pimr64
Pim proto-oncogene, serine/threonine kinase, related 64
chr7_-_57509447 0.12 ENSDART00000051973
ENSDART00000147036
sirt3
sirtuin 3
chr24_-_25691020 0.12 ENSDART00000015391
chrnd
cholinergic receptor, nicotinic, delta (muscle)
chr5_+_36752943 0.12 ENSDART00000017138
exoc3l2a
exocyst complex component 3-like 2a
chr18_-_48983690 0.12 ENSDART00000182359
FO681288.3

chr4_+_6572364 0.12 ENSDART00000122574
ppp1r3aa
protein phosphatase 1, regulatory subunit 3Aa
chr12_+_15148618 0.12 ENSDART00000125552
adprh
ADP-ribosylarginine hydrolase
chr11_+_44356707 0.11 ENSDART00000165219
srsf7b
serine/arginine-rich splicing factor 7b
chr10_-_14556978 0.11 ENSDART00000126643
zgc:153395
zgc:153395

Network of associatons between targets according to the STRING database.

First level regulatory network of alx4a+alx4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.3 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.4 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.4 GO:0051963 regulation of synapse assembly(GO:0051963)
0.1 0.4 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.3 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.1 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.2 GO:1901907 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.3 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.0 0.6 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.3 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.1 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.2 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0051228 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.0 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.3 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.0 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.3 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.0 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.1 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.0 0.2 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.8 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.0 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.6 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 0.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.2 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.1 0.4 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.2 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.0 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine