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PRJNA207719: Tissue specific transcriptome profiling

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Results for arid5b

Z-value: 0.58

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Transcription factors associated with arid5b

Gene Symbol Gene ID Gene Info
arid5b
ENSDARG00000037196 AT-rich interaction domain 5B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arid5bdr11_v1_chr12_+_8373525_8373525-0.884.7e-02Click!

Activity profile of arid5b motif

Sorted Z-values of arid5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_19299309 0.92 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr17_-_2584423 0.43 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr11_+_13224281 0.43 ENSDART00000102557
ENSDART00000178706
abcb11b
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr1_+_10051763 0.41 ENSDART00000011701
fgb
fibrinogen beta chain
chr17_-_2578026 0.39 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr21_-_2322102 0.38 ENSDART00000162867
zgc:66483
zgc:66483
chr13_-_4704353 0.36 ENSDART00000171900
oit3
oncoprotein induced transcript 3
chr12_-_46252062 0.36 ENSDART00000153223
si:ch211-226h7.5
si:ch211-226h7.5
chr16_-_50175069 0.35 ENSDART00000192979
lim2.5
lens intrinsic membrane protein 2.5
chr7_-_60831082 0.34 ENSDART00000073654
ENSDART00000136999
pcxb
pyruvate carboxylase b
chr9_-_2892045 0.34 ENSDART00000137201
cdca7a
cell division cycle associated 7a
chr6_-_49063085 0.32 ENSDART00000156124
si:ch211-105j21.9
si:ch211-105j21.9
chr21_-_1625976 0.32 ENSDART00000066621
vmo1b
vitelline membrane outer layer 1 homolog b
chr25_-_32363341 0.31 ENSDART00000153892
ENSDART00000114385
cep152
centrosomal protein 152
chr13_-_6252498 0.31 ENSDART00000115157
tuba4l
tubulin, alpha 4 like
chr9_-_2892250 0.30 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr12_-_46315898 0.29 ENSDART00000153138
si:ch211-226h7.3
si:ch211-226h7.3
chr12_+_20618522 0.27 ENSDART00000091452
si:dkey-220f10.4
si:dkey-220f10.4
chr23_-_27101600 0.24 ENSDART00000139231
stat6
signal transducer and activator of transcription 6, interleukin-4 induced
chr3_-_28828242 0.23 ENSDART00000151445
si:ch211-76l23.4
si:ch211-76l23.4
chr4_-_20043484 0.23 ENSDART00000167780
zgc:193726
zgc:193726
chr1_+_9994811 0.23 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
si:dkeyp-75b4.10
chr15_-_5624361 0.22 ENSDART00000176446
ENSDART00000114410
wdr62
WD repeat domain 62
chr7_+_29512673 0.22 ENSDART00000173895
si:dkey-182o15.5
si:dkey-182o15.5
chr4_-_14743655 0.22 ENSDART00000192518
BX571719.1

chr5_-_72390259 0.21 ENSDART00000172302
wbp1
WW domain binding protein 1
chr18_-_7448047 0.21 ENSDART00000193213
ENSDART00000131940
ENSDART00000186944
ENSDART00000052803
si:dkey-30c15.10
si:dkey-30c15.10
chr12_+_31783066 0.21 ENSDART00000105584
lrrc59
leucine rich repeat containing 59
chr16_+_27224068 0.20 ENSDART00000059013
sec61b
Sec61 translocon beta subunit
chr10_-_29101715 0.20 ENSDART00000149674
ENSDART00000171194
ENSDART00000192019
si:ch211-103f14.3
si:ch211-103f14.3
chr23_-_27589754 0.20 ENSDART00000138381
ENSDART00000133721
si:ch211-156j22.4
si:ch211-156j22.4
chr9_+_5862040 0.19 ENSDART00000129117
pdzk1
PDZ domain containing 1
chr5_-_1218801 0.19 ENSDART00000184398
CABZ01048143.1

chr16_+_41570653 0.19 ENSDART00000102665
aste1a
asteroid homolog 1a
chr2_-_17114852 0.19 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr14_-_46238186 0.19 ENSDART00000173245
si:ch211-113d11.6
si:ch211-113d11.6
chr19_+_9666961 0.18 ENSDART00000104596
ENSDART00000132124
si:dkey-14o18.6
si:dkey-14o18.6
chr9_-_11549379 0.18 ENSDART00000187074
fev
FEV (ETS oncogene family)
chr3_-_61205711 0.18 ENSDART00000055062
pvalb1
parvalbumin 1
chr23_-_27589508 0.18 ENSDART00000178404
si:ch211-156j22.4
si:ch211-156j22.4
chr3_-_40658820 0.18 ENSDART00000191948
rnf216
ring finger protein 216
chr18_+_5543677 0.18 ENSDART00000146161
ENSDART00000136189
nnt2
nicotinamide nucleotide transhydrogenase 2
chr2_-_14793343 0.18 ENSDART00000132264
si:ch73-366i20.1
si:ch73-366i20.1
chr3_-_34100700 0.17 ENSDART00000151628
ighv6-1
immunoglobulin heavy variable 6-1
chr10_-_244745 0.17 ENSDART00000136551
klhl35
kelch-like family member 35
chr18_+_3052408 0.17 ENSDART00000181563
kctd14
potassium channel tetramerization domain containing 14
chr5_+_61476014 0.17 ENSDART00000050906
lrwd1
leucine-rich repeats and WD repeat domain containing 1
chr2_-_37744951 0.17 ENSDART00000144807
myo9b
myosin IXb
chr3_+_22375596 0.17 ENSDART00000188243
ENSDART00000181506
arhgap27l
Rho GTPase activating protein 27, like
chr4_+_57099307 0.16 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr11_+_1551603 0.16 ENSDART00000185383
ENSDART00000121489
ENSDART00000040577
mybl2b
v-myb avian myeloblastosis viral oncogene homolog-like 2b
chr17_+_28611746 0.16 ENSDART00000156711
ENSDART00000113300
mis18bp1
MIS18 binding protein 1
chr21_-_11970199 0.16 ENSDART00000114524
nop56
NOP56 ribonucleoprotein homolog
chr25_+_35133404 0.16 ENSDART00000188505
hist1h2a2
histone cluster 1 H2A family member 2
chr22_+_19478140 0.16 ENSDART00000135291
ENSDART00000136576
si:dkey-78l4.8
si:dkey-78l4.8
chr21_+_21741804 0.15 ENSDART00000112068
defbl1
defensin, beta-like 1
chr4_+_53119675 0.15 ENSDART00000167470
si:dkey-8o9.2
si:dkey-8o9.2
chr22_-_10586191 0.15 ENSDART00000148418
si:dkey-42i9.16
si:dkey-42i9.16
chr22_+_19311411 0.15 ENSDART00000133234
ENSDART00000138284
si:dkey-21e2.16
si:dkey-21e2.16
chr19_-_10330778 0.15 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
ccdc106b
coiled-coil domain containing 106b
chr16_-_25606235 0.15 ENSDART00000192741
zgc:110410
zgc:110410
chr2_+_45548890 0.14 ENSDART00000113994
fndc7a
fibronectin type III domain containing 7a
chr11_-_33960318 0.14 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr13_+_35635672 0.14 ENSDART00000148481
thbs2a
thrombospondin 2a
chr5_+_26847190 0.14 ENSDART00000076742
imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr24_-_7728409 0.13 ENSDART00000131392
ptprh
protein tyrosine phosphatase, receptor type, h
chr17_-_51224800 0.13 ENSDART00000150089
psen1
presenilin 1
chr18_-_16953978 0.12 ENSDART00000100126
akip1
A kinase (PRKA) interacting protein 1
chr8_-_49201258 0.12 ENSDART00000114584
ENSDART00000142172
zgc:171501
zgc:171501
chr13_+_25455319 0.12 ENSDART00000145948
pkd2l1
polycystic kidney disease 2-like 1
chr21_+_3021702 0.12 ENSDART00000188235
CABZ01023247.1

chr21_-_38581903 0.12 ENSDART00000148939
pof1b
POF1B, actin binding protein
chr4_+_76735113 0.12 ENSDART00000075602
ms4a17a.6
membrane-spanning 4-domains, subfamily A, member 17A.6
chr15_-_1485086 0.12 ENSDART00000191651
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr7_+_22792132 0.12 ENSDART00000135207
ENSDART00000146801
rbm4.3
RNA binding motif protein 4.3
chr3_+_23047241 0.12 ENSDART00000103858
b4galnt2.2
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr1_+_7956030 0.12 ENSDART00000159655
CR855320.1

chr5_-_38155005 0.11 ENSDART00000097770
gucy2d
guanylate cyclase 2D, retinal
chr12_+_20618336 0.11 ENSDART00000084007
si:dkey-220f10.4
si:dkey-220f10.4
chr4_-_76154252 0.10 ENSDART00000161269
BX957252.1

chr3_+_709393 0.10 ENSDART00000191970
AL929520.3

chr4_+_54618332 0.10 ENSDART00000171824
si:ch211-227e10.2
si:ch211-227e10.2
chr15_-_37589600 0.10 ENSDART00000154641
proser3
proline and serine rich 3
chr4_-_68868229 0.10 ENSDART00000159219
si:dkey-264f17.5
si:dkey-264f17.5
chr20_+_33924235 0.10 ENSDART00000146292
ENSDART00000139609
lmx1a
LIM homeobox transcription factor 1, alpha
chr10_-_18463934 0.10 ENSDART00000133116
ENSDART00000113422
si:dkey-28o19.1
si:dkey-28o19.1
chr7_+_57109214 0.10 ENSDART00000135068
ENSDART00000098412
enosf1
enolase superfamily member 1
chr17_+_51224421 0.10 ENSDART00000025229
adi1
acireductone dioxygenase 1
chr23_-_31506854 0.10 ENSDART00000131352
ENSDART00000138625
ENSDART00000133002
eya4
EYA transcriptional coactivator and phosphatase 4
chr4_-_32458542 0.10 ENSDART00000127211
si:dkey-16p6.1
si:dkey-16p6.1
chr15_-_47812268 0.10 ENSDART00000190231
tomt
transmembrane O-methyltransferase
chr10_-_35410518 0.10 ENSDART00000048430
gabrr3a
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr16_-_27224000 0.09 ENSDART00000126347
alg2
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
chr7_+_38510197 0.09 ENSDART00000173468
ENSDART00000100479
slc7a9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr9_+_29985010 0.08 ENSDART00000020743
cmss1
cms1 ribosomal small subunit homolog (yeast)
chr2_-_3077027 0.08 ENSDART00000109319
arf1
ADP-ribosylation factor 1
chr11_+_21137948 0.08 ENSDART00000110673
il10
interleukin 10
chr11_+_42765963 0.07 ENSDART00000156080
ENSDART00000179888
tdrd3
tudor domain containing 3
chr3_-_4303262 0.07 ENSDART00000112819
si:dkey-73p2.2
si:dkey-73p2.2
chr9_+_2020667 0.07 ENSDART00000157818
lnpa
limb and neural patterns a
chr21_-_38582061 0.07 ENSDART00000193891
ENSDART00000124349
pof1b
POF1B, actin binding protein
chr2_+_42072231 0.07 ENSDART00000084517
vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr13_-_30149973 0.07 ENSDART00000041515
sar1ab
secretion associated, Ras related GTPase 1Ab
chr1_+_58066109 0.07 ENSDART00000115190
si:ch211-114l13.4
si:ch211-114l13.4
chr13_+_18523661 0.07 ENSDART00000034852
tlr4bb
toll-like receptor 4b, duplicate b
chr15_+_24572926 0.06 ENSDART00000155636
ENSDART00000187800
dhrs13b
dehydrogenase/reductase (SDR family) member 13b
chr17_+_15213496 0.06 ENSDART00000058351
ENSDART00000131663
gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr22_+_10757848 0.06 ENSDART00000145551
tmprss9
transmembrane protease, serine 9
chr16_-_14552199 0.06 ENSDART00000133368
si:dkey-237j11.3
si:dkey-237j11.3
chr15_-_1484795 0.06 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr7_-_5316901 0.06 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
si:cabz01074946.1
chr4_-_77377596 0.05 ENSDART00000186068
slco1e1
solute carrier organic anion transporter family, member 1E1
chr4_+_20177526 0.05 ENSDART00000017947
ENSDART00000135451
ccdc146
coiled-coil domain containing 146
chr20_-_49657134 0.05 ENSDART00000151248
col12a1b
collagen, type XII, alpha 1b
chr13_+_30215765 0.05 ENSDART00000041026
ENSDART00000133049
qrfpra
pyroglutamylated RFamide peptide receptor a
chr4_-_32458327 0.05 ENSDART00000182527
si:dkey-16p6.1
si:dkey-16p6.1
chr6_-_6254432 0.04 ENSDART00000081952
rtn4a
reticulon 4a
chr13_-_30150592 0.04 ENSDART00000143093
sar1ab
secretion associated, Ras related GTPase 1Ab
chr20_+_51466046 0.04 ENSDART00000178065
tlr5b
toll-like receptor 5b
chr9_+_21281652 0.04 ENSDART00000113352
lats2
large tumor suppressor kinase 2
chr12_+_48683208 0.04 ENSDART00000188582
mmp21
matrix metallopeptidase 21
chr4_-_76205022 0.04 ENSDART00000159687
ENSDART00000187593
si:ch211-106j21.5
si:ch211-106j21.5
chr4_+_49196098 0.03 ENSDART00000150678
si:dkey-40n15.1
si:dkey-40n15.1
chr14_+_20351 0.03 ENSDART00000051893
stx18
syntaxin 18
chr16_-_42303856 0.03 ENSDART00000180030
ppox
protoporphyrinogen oxidase
chr10_+_8481660 0.03 ENSDART00000109559
BX682234.1

chr5_+_61998641 0.03 ENSDART00000137110
selenow1
selenoprotein W, 1
chr19_-_11977783 0.03 ENSDART00000183337
si:ch1073-296d18.1
si:ch1073-296d18.1
chr25_+_9027831 0.03 ENSDART00000155855
im:7145024
im:7145024
chr21_+_3928947 0.03 ENSDART00000149777
setx
senataxin
chr11_-_18017918 0.03 ENSDART00000040171
qrich1
glutamine-rich 1
chr10_-_28193642 0.03 ENSDART00000019050
rps6kb1a
ribosomal protein S6 kinase b, polypeptide 1a
chr12_+_8074343 0.03 ENSDART00000124084
cabcoco1
ciliary associated calcium binding coiled-coil 1
chr7_+_13491452 0.03 ENSDART00000053535
arih1l
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr21_+_41839443 0.03 ENSDART00000010942
rnf14
ring finger protein 14
chr4_-_71151245 0.03 ENSDART00000165415
si:dkey-193i10.4
si:dkey-193i10.4
chr21_+_43172506 0.03 ENSDART00000121725
zcchc10
zinc finger, CCHC domain containing 10
chr22_-_19102256 0.03 ENSDART00000171866
ENSDART00000166295
polrmt
polymerase (RNA) mitochondrial (DNA directed)
chr16_+_37876779 0.03 ENSDART00000140148
si:ch211-198c19.1
si:ch211-198c19.1
chr1_+_58602506 0.03 ENSDART00000158425
si:ch73-221f6.1
si:ch73-221f6.1
chr14_-_8940499 0.02 ENSDART00000129030
zgc:153681
zgc:153681
chr6_-_9646275 0.02 ENSDART00000012903
wdr12
WD repeat domain 12
chr25_-_2355107 0.02 ENSDART00000056121
mrps35
mitochondrial ribosomal protein S35
chr5_-_69523816 0.02 ENSDART00000112692
si:ch211-157p22.10
si:ch211-157p22.10
chr23_+_6926183 0.02 ENSDART00000149882
si:ch211-117c9.1
si:ch211-117c9.1
chr19_+_30884706 0.01 ENSDART00000052126
yars
tyrosyl-tRNA synthetase
chr7_+_17433836 0.01 ENSDART00000080346
nitr2a
novel immune-type receptor 2a
chr11_+_7183025 0.01 ENSDART00000046670
ENSDART00000154009
ENSDART00000156974
ENSDART00000125619
thop1
thimet oligopeptidase 1
chr18_+_7543347 0.01 ENSDART00000103467
arf5
ADP-ribosylation factor 5
chr6_-_18971063 0.00 ENSDART00000188163
sept9b
septin 9b
chr24_+_39638555 0.00 ENSDART00000078313
luc7l
LUC7-like (S. cerevisiae)
chr9_-_52814204 0.00 ENSDART00000140771
ENSDART00000007401
MAP3K13
si:ch211-45c16.2
chr11_+_42726712 0.00 ENSDART00000028955
tdrd3
tudor domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of arid5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 0.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.8 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0071169 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.0 0.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.2 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.1 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.4 GO:0070527 platelet aggregation(GO:0070527) blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:1903373 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.0 0.1 GO:0071267 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.2 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.6 GO:0048538 thymus development(GO:0048538)
0.0 0.1 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.0 0.3 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.1 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.3 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.4 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4