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PRJNA207719: Tissue specific transcriptome profiling

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Results for atf1

Z-value: 1.64

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Transcription factors associated with atf1

Gene Symbol Gene ID Gene Info
ENSDARG00000044301 activating transcription factor 1
ENSDARG00000109865 activating transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf1dr11_v1_chr6_-_39521832_395218320.148.2e-01Click!

Activity profile of atf1 motif

Sorted Z-values of atf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_12385308 2.05 ENSDART00000080927
synaptosomal-associated protein, 25b
chr6_+_27667359 1.88 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr15_-_163586 1.65 ENSDART00000163597
septin-4
chr5_+_3501859 1.62 ENSDART00000080486
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr24_-_7632187 1.57 ENSDART00000041714
ATPase H+ transporting V0 subunit a1b
chr9_-_296169 1.54 ENSDART00000165228
kinesin family member 5A, a
chr23_-_4915118 1.47 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr23_+_28731379 1.34 ENSDART00000047378
cortistatin
chr16_+_36906693 1.34 ENSDART00000160645
si:ch73-215d9.1
chr23_-_29667716 1.34 ENSDART00000158302
ENSDART00000133902
calsyntenin 1
chr14_-_7888748 1.31 ENSDART00000166293
protein phosphatase 3, catalytic subunit, beta isozyme
chr1_-_56223913 1.31 ENSDART00000019573
zgc:65894
chr4_+_9669717 1.30 ENSDART00000004604
si:dkey-153k10.9
chr4_-_12388535 1.30 ENSDART00000017180
RERG/RAS-like a
chr16_-_29437373 1.30 ENSDART00000148405
si:ch211-113g11.6
chr20_+_34913069 1.28 ENSDART00000007584
synaptosomal-associated protein, 25a
chr24_-_6158933 1.22 ENSDART00000021609
glutamate decarboxylase 2
chr2_-_11512819 1.21 ENSDART00000142013
proenkephalin a
chr2_-_42415902 1.21 ENSDART00000142489
solute carrier organic anion transporter family member 5A1b
chr19_+_24882845 1.18 ENSDART00000010580
si:ch211-195b13.1
chr1_-_38756870 1.16 ENSDART00000130324
ENSDART00000148404
glycoprotein M6Ab
chr21_-_43606502 1.14 ENSDART00000151030
si:ch73-362m14.4
chr23_-_29667544 1.13 ENSDART00000059339
calsyntenin 1
chr3_-_49566364 1.13 ENSDART00000161507
zgc:153426
chr3_+_15907297 1.11 ENSDART00000139206
mitogen-activated protein kinase 8 interacting protein 3
chr8_+_44714336 1.11 ENSDART00000145801
ELMO/CED-12 domain containing 3
chr9_+_219124 1.07 ENSDART00000161484
mitogen-activated protein kinase kinase kinase 12
chr12_-_19103490 1.06 ENSDART00000060561
cold shock domain containing C2, RNA binding a
chr25_-_31863374 1.05 ENSDART00000028338
secretory carrier membrane protein 5a
chr21_-_23308286 1.04 ENSDART00000184419
zinc finger and BTB domain containing 16a
chr5_+_37056818 1.04 ENSDART00000036760
tubulin polymerization-promoting protein family member 2
chr7_+_29133321 1.03 ENSDART00000052346
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr11_-_44163164 1.01 ENSDART00000047126
chloride channel, voltage-sensitive 4
chr7_-_12065668 1.00 ENSDART00000101537
mex-3 RNA binding family member B
chr3_-_2593859 1.00 ENSDART00000143826
si:dkey-217f16.5
chr7_+_40228422 0.99 ENSDART00000052222
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr25_-_23052707 0.98 ENSDART00000024633
dual specificity phosphatase 8a
chr10_-_22845485 0.98 ENSDART00000079454
vesicle-associated membrane protein 2
chr25_+_35683956 0.97 ENSDART00000149768
kinesin family member 21A
chr23_+_23183449 0.97 ENSDART00000132296
kelch-like family member 17
chr20_+_29743904 0.97 ENSDART00000146366
ENSDART00000153154
kinase D-interacting substrate 220b
chr17_-_20979077 0.97 ENSDART00000006676
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr7_+_13382852 0.96 ENSDART00000166318
diacylglycerol lipase, alpha
chr6_+_24817852 0.96 ENSDART00000165609
BarH-like homeobox 2
chr19_+_16222618 0.96 ENSDART00000137189
ENSDART00000169246
ENSDART00000190583
ENSDART00000189521
protein tyrosine phosphatase, receptor type, U, a
chr19_-_1961024 0.95 ENSDART00000108784
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr20_+_20637866 0.94 ENSDART00000060203
ENSDART00000079079
reticulon 1b
chr7_+_39166460 0.94 ENSDART00000052318
ENSDART00000146635
ENSDART00000173877
ENSDART00000173767
ENSDART00000173600
midkine a
chr15_-_27710513 0.93 ENSDART00000005641
ENSDART00000134373
LIM homeobox 1a
chr10_-_36591511 0.92 ENSDART00000063347
solute carrier family 1 (glial high affinity glutamate transporter), member 3b
chr5_-_45876908 0.91 ENSDART00000188229
solute carrier family 4 (sodium bicarbonate cotransporter), member 4a
chr18_+_21408794 0.90 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr3_-_1204341 0.90 ENSDART00000089646
family with sequence similarity 234, member B
chr10_+_32683089 0.89 ENSDART00000063551
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr20_+_20638034 0.88 ENSDART00000189759
reticulon 1b
chr9_-_54840124 0.88 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr12_-_30443562 0.88 ENSDART00000020769
adrenoceptor beta 1
chr17_-_26911852 0.86 ENSDART00000045842
regulator of calcineurin 3
chr17_+_8184649 0.85 ENSDART00000091818
tubby like protein 4b
chr7_+_26224211 0.84 ENSDART00000173999
VGF nerve growth factor inducible
chr2_+_20332044 0.84 ENSDART00000112131
phospholipid phosphatase related 4a
chr13_-_31470439 0.83 ENSDART00000076574
reticulon 1a
chr21_+_11684830 0.82 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr16_+_34523515 0.81 ENSDART00000041007
stathmin 1b
chr5_-_63109232 0.81 ENSDART00000115128
ubiquitin specific peptidase 2b
chr5_-_45877387 0.81 ENSDART00000183714
ENSDART00000041503
solute carrier family 4 (sodium bicarbonate cotransporter), member 4a
chr1_+_41666611 0.81 ENSDART00000145789
F-box protein 41
chr11_-_13341483 0.80 ENSDART00000164978
microtubule associated serine/threonine kinase 3b
chr17_+_29345606 0.80 ENSDART00000086164
potassium channel tetramerization domain containing 3
chr19_-_43552252 0.79 ENSDART00000138308
G protein-coupled receptor 186
chr7_-_23563092 0.79 ENSDART00000132275
G protein-coupled receptor 185 b
chr13_+_23843712 0.78 ENSDART00000057611
opioid receptor, mu 1
chr10_-_24371312 0.78 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr21_-_23307653 0.77 ENSDART00000140284
ENSDART00000134103
zinc finger and BTB domain containing 16a
chr4_-_16124417 0.77 ENSDART00000128079
ENSDART00000077664
ATPase plasma membrane Ca2+ transporting 1a
chr15_+_28685625 0.77 ENSDART00000188797
ENSDART00000166036
neuro-oncological ventral antigen 2
chr21_+_11685009 0.77 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr11_+_40649412 0.77 ENSDART00000043016
ENSDART00000134560
solute carrier family 45, member 1
chr18_-_19405616 0.77 ENSDART00000191290
ENSDART00000090855
multiple EGF-like-domains 11
chr15_+_28685892 0.76 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr8_-_17771755 0.76 ENSDART00000063592
protein kinase C, zeta
chr6_-_31348999 0.76 ENSDART00000153734
DnaJ (Hsp40) homolog, subfamily C, member 6
chr4_-_5764255 0.74 ENSDART00000113864
failed axon connections homolog a
chr6_-_58828398 0.74 ENSDART00000090634
kinesin family member 5A, b
chr17_-_11329959 0.74 ENSDART00000015418
interferon regulatory factor 2 binding protein-like
chr20_+_41549200 0.73 ENSDART00000135715
family with sequence similarity 184, member A
chr18_-_14743659 0.73 ENSDART00000125979
teashirt zinc finger homeobox 3a
chr1_+_9290103 0.73 ENSDART00000055009
Unc4.1 homeobox (C. elegans)
chr14_-_2270973 0.72 ENSDART00000180729
protocadherin 2 alpha b 9
chr20_+_38724575 0.72 ENSDART00000015095
ENSDART00000152972
urotensin 1
chr2_-_6292510 0.71 ENSDART00000092182
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr13_-_50672341 0.71 ENSDART00000190498

chr8_+_29742237 0.71 ENSDART00000133955
ENSDART00000020621
mitogen-activated protein kinase 4
chr7_+_67486807 0.71 ENSDART00000159989
copine VII
chr8_-_6943155 0.71 ENSDART00000139545
ENSDART00000033294
WD repeat domain 13
chr13_+_24834199 0.71 ENSDART00000101274
zgc:153981
chr13_-_40499296 0.70 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr12_-_41619257 0.70 ENSDART00000162967
dihydropyrimidinase-like 4
chr2_-_56635744 0.70 ENSDART00000167790
ENSDART00000168160
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b
chr9_+_6997861 0.70 ENSDART00000190491
inositol polyphosphate-4-phosphatase type I Aa
chr10_-_7858553 0.70 ENSDART00000182010
inositol polyphosphate-5-phosphatase Ja
chr8_-_17067364 0.70 ENSDART00000132687
RAB3C, member RAS oncogene family
chr16_-_32649929 0.69 ENSDART00000136161
failed axon connections homolog b
chr14_-_33454595 0.69 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr21_-_14878220 0.69 ENSDART00000131237
unc-51 like autophagy activating kinase 1
chr19_+_10396042 0.69 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr8_-_54223316 0.68 ENSDART00000018054
thyrotropin-releasing hormone
chr24_-_21172122 0.68 ENSDART00000154259
ATPase H+ transporting V1 subunit Ab
chr13_-_16191674 0.68 ENSDART00000147868
von Willebrand factor C domain containing 2
chr2_+_22694382 0.68 ENSDART00000139196
kinesin family member 1Ab
chr20_+_3108597 0.68 ENSDART00000133435
si:ch73-212j7.1
chr1_-_22861348 0.68 ENSDART00000139412
si:dkey-92j12.6
chr10_+_23022263 0.67 ENSDART00000138955
si:dkey-175g6.2
chr2_+_20331445 0.67 ENSDART00000186880
phospholipid phosphatase related 4a
chr19_-_32888758 0.67 ENSDART00000052080
lysosomal protein transmembrane 4 beta
chr9_+_6998082 0.67 ENSDART00000092480
ENSDART00000135576
ENSDART00000188884
inositol polyphosphate-4-phosphatase type I Aa
chr25_-_31763897 0.66 ENSDART00000041740
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr8_-_39984593 0.66 ENSDART00000140127
aspartate beta-hydroxylase domain containing 2
chr16_-_9869056 0.66 ENSDART00000149312
neurocalcin delta a
chr5_-_23999777 0.66 ENSDART00000085969
MAP7 domain containing 2a
chr16_-_17162843 0.65 ENSDART00000089386
intermediate filament family orphan 1b
chr3_-_18373604 0.65 ENSDART00000148132
sperm associated antigen 9a
chr16_+_5184402 0.65 ENSDART00000156685
SOGA family member 3a
chr12_+_27243059 0.64 ENSDART00000066269
ADP-ribosylation factor-like 4D
chr5_-_41560874 0.64 ENSDART00000136702
DnaJ (Hsp40) homolog, subfamily B, member 5
chr23_+_45584223 0.64 ENSDART00000149367
si:ch73-290k24.5
chr1_-_19215336 0.63 ENSDART00000162949
ENSDART00000170680
protein tyrosine phosphatase, receptor type, D, b
chr19_+_45970692 0.63 ENSDART00000158781
si:ch211-153f2.7
chr23_+_2136344 0.63 ENSDART00000085290
ENSDART00000092757
cytoplasmic polyadenylation element binding protein 2
chr11_+_6819050 0.63 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr8_+_21588067 0.62 ENSDART00000172190
adherens junctions associated protein 1
chr4_+_5156117 0.62 ENSDART00000067392
tp53-induced glycolysis and apoptosis regulator b
chr3_-_18373425 0.61 ENSDART00000178522
sperm associated antigen 9a
chr13_+_28705143 0.60 ENSDART00000183338
LIM domain binding 1a
chr21_+_9576176 0.60 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mitogen-activated protein kinase 10
chr20_+_41549735 0.60 ENSDART00000184235
family with sequence similarity 184, member A
chr3_-_62380146 0.60 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr1_-_54947592 0.60 ENSDART00000129710
cartilage acidic protein 1a
chr5_-_24000211 0.59 ENSDART00000188865
MAP7 domain containing 2a
chr11_-_6970107 0.59 ENSDART00000171255
si:ch211-43f4.1
chr10_-_45379831 0.58 ENSDART00000186205

chr17_-_15382704 0.58 ENSDART00000005313
zgc:85722
chr15_-_28200049 0.58 ENSDART00000004200
sterile alpha and TIR motif containing 1
chr24_-_6375774 0.58 ENSDART00000013294
annexin A13
chr18_-_19103929 0.58 ENSDART00000188370
ENSDART00000177621
DENN/MADD domain containing 4A
chr7_-_44963154 0.57 ENSDART00000073735
Ras-related associated with diabetes
chr3_+_61221194 0.57 ENSDART00000110030
lemur tyrosine kinase 2
chr9_+_22631672 0.57 ENSDART00000101770
ENSDART00000126015
ENSDART00000145005
ets variant 5a
chr5_-_57879138 0.56 ENSDART00000145959
salt-inducible kinase 2a
chr1_+_45323400 0.56 ENSDART00000148906
ENSDART00000132366
epithelial membrane protein 1
chr22_-_21392748 0.56 ENSDART00000144648
ankyrin repeat domain 24
chr20_-_1191910 0.56 ENSDART00000043218
ubiquitin-conjugating enzyme E2, J1
chr10_+_44903676 0.56 ENSDART00000158553
zgc:114173
chr7_+_7552008 0.55 ENSDART00000173018
ENSDART00000049311
chloride channel 3
chr2_-_58201173 0.55 ENSDART00000166282
purine nucleoside phosphorylase 5b
chr16_+_26766423 0.55 ENSDART00000048036
GTP binding protein overexpressed in skeletal muscle
chr17_+_23554932 0.54 ENSDART00000135814
pantothenate kinase 1a
chr5_-_20814576 0.54 ENSDART00000098682
ENSDART00000147639
si:ch211-225b11.1
chr20_+_36682051 0.54 ENSDART00000130513
nuclear receptor coactivator 1
chr8_+_3085120 0.54 ENSDART00000148020
ENSDART00000136250
LIM homeobox 2b
chr23_-_33654889 0.53 ENSDART00000146180
cysteine-serine-rich nuclear protein 2
chr1_+_10305611 0.53 ENSDART00000043881
zgc:77880
chr14_+_790166 0.53 ENSDART00000123912
adrenergic, alpha-2D-, receptor a
chr25_-_24074500 0.53 ENSDART00000040410
tyrosine hydroxylase
chr12_+_32159272 0.52 ENSDART00000153167
hepatic leukemia factor b
chr22_-_600016 0.52 ENSDART00000086434
transmembrane and coiled-coil domain family 2
chr7_-_48805181 0.52 ENSDART00000015884
milk fat globule-EGF factor 8 protein a
chr19_-_10395683 0.52 ENSDART00000109488
zgc:194578
chr2_-_30324610 0.52 ENSDART00000185422
junctophilin 1b
chr2_+_35603637 0.52 ENSDART00000147278
polo-like kinase 3 (Drosophila)
chr15_+_5116179 0.52 ENSDART00000101937
phosphoglucomutase 2-like 1
chr4_-_69189894 0.51 ENSDART00000169596
si:ch211-209j12.1
chr3_-_62393449 0.51 ENSDART00000101870
ENSDART00000140782
ENSDART00000181704
protein Z, vitamin K-dependent plasma glycoprotein a
chr5_+_62374092 0.51 ENSDART00000082965

chr21_+_25054420 0.51 ENSDART00000065132
zgc:171740
chr20_+_2950005 0.50 ENSDART00000135919
adenosylmethionine decarboxylase 1
chr14_+_8947282 0.50 ENSDART00000047993
ribosomal protein S6 kinase a, like
chr9_-_13963078 0.50 ENSDART00000193398
ENSDART00000061156
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr10_+_37145007 0.50 ENSDART00000131777
CUE domain containing 1a
chr18_-_5781922 0.50 ENSDART00000128722
si:ch73-167i17.6
chr4_+_74131530 0.50 ENSDART00000174125

chr6_-_46403475 0.50 ENSDART00000154148
calcium/calmodulin-dependent protein kinase Ia
chr13_-_3155243 0.49 ENSDART00000139183
ENSDART00000050934
protein kinase domain containing, cytoplasmic a
chr11_-_18800299 0.49 ENSDART00000156276
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr21_-_25522510 0.49 ENSDART00000162711
connector enhancer of kinase suppressor of Ras 2b
chr13_-_40754499 0.49 ENSDART00000111641
ENSDART00000159255
MORN repeat containing 4
chr2_+_11685742 0.49 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr19_-_3488860 0.48 ENSDART00000172520
human immunodeficiency virus type I enhancer binding protein 1
chr4_-_1801519 0.48 ENSDART00000188604
ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr1_-_11291324 0.48 ENSDART00000091205
sidekick cell adhesion molecule 1b
chr6_-_25952848 0.48 ENSDART00000076997
ENSDART00000148748
LIM domain only 4b
chr14_-_48939560 0.48 ENSDART00000021736
short coiled-coil protein b
chr9_+_42546504 0.47 ENSDART00000192224
GULP, engulfment adaptor PTB domain containing 1a
chr9_-_31524907 0.47 ENSDART00000142904
ENSDART00000127214
ENSDART00000133427
ENSDART00000146268
ENSDART00000182541
ENSDART00000184736
transmembrane and tetratricopeptide repeat containing 4
chr8_+_50983551 0.47 ENSDART00000142061
si:dkey-32e23.4
chr4_+_73973242 0.47 ENSDART00000182529

chr16_+_25137483 0.47 ENSDART00000155666
zinc finger protein 576, tandem duplicate 1
chr12_-_41618844 0.47 ENSDART00000160054
dihydropyrimidinase-like 4
chr16_-_45069882 0.47 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr12_+_28298859 0.46 ENSDART00000183366

Network of associatons between targets according to the STRING database.

First level regulatory network of atf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 1.6 GO:1903792 negative regulation of anion transport(GO:1903792)
0.4 1.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.4 3.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.3 0.9 GO:0097378 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.2 1.0 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.2 1.1 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 0.6 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.2 0.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 0.6 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.2 1.0 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.2 1.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.2 0.7 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.2 0.5 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.2 0.9 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.2 2.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.2 0.8 GO:0034505 tooth mineralization(GO:0034505)
0.2 0.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 2.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.5 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.9 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.8 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.4 GO:0044038 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.4 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 2.3 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 1.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.2 GO:1990592 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 1.6 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 1.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 0.5 GO:1901907 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.4 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.1 0.7 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 1.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.7 GO:0008216 spermidine metabolic process(GO:0008216)
0.1 0.5 GO:0021794 thalamus development(GO:0021794)
0.1 1.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.1 0.5 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.0 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.3 GO:0035522 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 1.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 2.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.6 GO:0061709 reticulophagy(GO:0061709)
0.1 1.9 GO:0030641 regulation of cellular pH(GO:0030641)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.2 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.2 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.1 0.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 1.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.4 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
0.1 0.8 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.1 0.4 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.5 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 1.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.9 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.2 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0045056 transcytosis(GO:0045056)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.1 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.9 GO:0060541 respiratory system development(GO:0060541)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.4 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.3 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0014005 microglia development(GO:0014005)
0.0 0.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 1.0 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.6 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0009268 response to pH(GO:0009268)
0.0 0.4 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.0 0.3 GO:0051893 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.0 GO:0014004 microglia differentiation(GO:0014004)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.4 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.1 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.4 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0032262 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.0 1.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.3 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0030719 P granule organization(GO:0030719)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.7 GO:0046785 microtubule polymerization(GO:0046785)
0.0 1.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 1.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 1.0 GO:0007254 JNK cascade(GO:0007254)
0.0 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.0 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.0 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.0 GO:0033212 iron assimilation(GO:0033212)
0.0 0.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 4.3 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.1 GO:0060546 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.0 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.0 0.1 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956) positive regulation of regulated secretory pathway(GO:1903307)
0.0 0.9 GO:0006096 glycolytic process(GO:0006096)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0090311 regulation of histone deacetylation(GO:0031063) regulation of protein deacetylation(GO:0090311)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.6 GO:0007338 single fertilization(GO:0007338)
0.0 0.0 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.0 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.3 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.6 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.4 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.0 0.0 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.1 GO:0050771 negative regulation of axon extension(GO:0030517) negative regulation of axonogenesis(GO:0050771)
0.0 0.1 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.0 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.0 2.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 1.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 1.3 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.6 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.6 GO:0070062 extracellular exosome(GO:0070062)
0.1 1.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.2 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.4 GO:0070724 BMP receptor complex(GO:0070724)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.3 GO:0016460 myosin II complex(GO:0016460)
0.1 0.3 GO:0033503 HULC complex(GO:0033503)
0.1 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 4.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 1.6 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 1.2 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.2 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 3.0 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 3.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0008432 JUN kinase binding(GO:0008432)
0.4 1.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 0.8 GO:0038046 enkephalin receptor activity(GO:0038046)
0.2 1.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 0.9 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.2 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 0.6 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 1.9 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.4 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.4 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.1 1.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 0.5 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 4.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.5 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 3.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.3 GO:0015222 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.1 0.5 GO:0051379 alpha2-adrenergic receptor activity(GO:0004938) epinephrine binding(GO:0051379)
0.1 0.7 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 1.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 2.0 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.6 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.7 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.6 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.3 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 1.0 GO:0051117 ATPase binding(GO:0051117)
0.1 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 1.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 5.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.4 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 1.0 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.2 GO:1990239 steroid hormone binding(GO:1990239)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 3.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.0 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.3 GO:0015293 symporter activity(GO:0015293)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.7 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.0 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 1.6 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis