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PRJNA207719: Tissue specific transcriptome profiling

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Results for barhl2

Z-value: 0.77

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Transcription factors associated with barhl2

Gene Symbol Gene ID Gene Info
barhl2
ENSDARG00000104361 BarH-like homeobox 2
barhl2
ENSDARG00000114681 BarH-like homeobox 2
barhl2
ENSDARG00000115723 BarH-like homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barhl2dr11_v1_chr6_+_24817852_24817852-0.884.8e-02Click!

Activity profile of barhl2 motif

Sorted Z-values of barhl2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_52437056 0.54 ENSDART00000138337
si:ch211-217k17.12
si:ch211-217k17.12
chr12_+_20352400 0.43 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr24_-_4765740 0.40 ENSDART00000121576
cpb1
carboxypeptidase B1 (tissue)
chr15_+_34699585 0.40 ENSDART00000017569
tnfb
tumor necrosis factor b (TNF superfamily, member 2)
chr4_+_73606482 0.36 ENSDART00000150765
si:ch211-165i18.2
si:ch211-165i18.2
chr21_+_25777425 0.35 ENSDART00000021620
cldnd
claudin d
chr15_-_2640966 0.35 ENSDART00000063320
cldne
claudin e
chr1_+_40802454 0.34 ENSDART00000193568
cpz
carboxypeptidase Z
chr1_-_19845378 0.34 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
grhprb
glyoxylate reductase/hydroxypyruvate reductase b
chr7_+_13988075 0.34 ENSDART00000186812
furina
furin (paired basic amino acid cleaving enzyme) a
chr16_-_26140768 0.33 ENSDART00000143960
cd79a
CD79a molecule, immunoglobulin-associated alpha
chr14_+_14568437 0.33 ENSDART00000164749
pcdh20
protocadherin 20
chr8_+_23738122 0.33 ENSDART00000062983
rpl10a
ribosomal protein L10a
chr11_+_6136220 0.32 ENSDART00000082223
tax1bp3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr1_-_513762 0.32 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr3_-_20091964 0.31 ENSDART00000029386
ENSDART00000020253
ENSDART00000124326
slc4a1a
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr6_-_8362419 0.31 ENSDART00000142752
ENSDART00000135810
acp5a
acid phosphatase 5a, tartrate resistant
chr19_+_10855158 0.31 ENSDART00000172219
ENSDART00000170826
apoea
apolipoprotein Ea
chr23_+_38171186 0.30 ENSDART00000148188
zgc:112994
zgc:112994
chr5_-_34993242 0.30 ENSDART00000134516
ENSDART00000051295
btf3
basic transcription factor 3
chr17_+_25849332 0.30 ENSDART00000191994
acss1
acyl-CoA synthetase short chain family member 1
chr22_+_10066846 0.29 ENSDART00000105916
ENSDART00000105914
ENSDART00000132480
si:ch211-222k6.3
si:ch211-222k6.3
chr5_-_42272517 0.29 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr8_-_38201415 0.29 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr10_-_13343831 0.28 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr1_-_33645967 0.28 ENSDART00000192758
cldng
claudin g
chr20_+_38257766 0.28 ENSDART00000147485
ENSDART00000149160
ccl38.6
chemokine (C-C motif) ligand 38, duplicate 6
chr16_+_7697878 0.28 ENSDART00000104176
ENSDART00000172977
ccr11.1
chemokine (C-C motif) receptor 11.1
chr20_-_54924593 0.28 ENSDART00000151522
si:dkey-15f23.1
si:dkey-15f23.1
chr16_-_23797570 0.28 ENSDART00000077834
rps27.2
ribosomal protein S27, isoform 2
chr11_-_22303678 0.28 ENSDART00000159527
ENSDART00000159681
tfeb
transcription factor EB
chr23_-_19715557 0.28 ENSDART00000143764
rpl10
ribosomal protein L10
chr9_+_14010823 0.27 ENSDART00000143837
si:ch211-67e16.3
si:ch211-67e16.3
chr5_+_9246458 0.27 ENSDART00000081772
susd1
sushi domain containing 1
chr3_-_32541033 0.27 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr16_+_23398369 0.27 ENSDART00000037694
s100a10b
S100 calcium binding protein A10b
chr11_-_7261717 0.27 ENSDART00000128959
zgc:113223
zgc:113223
chr22_-_24297510 0.27 ENSDART00000163297
si:ch211-117l17.6
si:ch211-117l17.6
chr5_-_38820046 0.27 ENSDART00000182886
cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr8_+_13389115 0.26 ENSDART00000184428
ENSDART00000154266
ENSDART00000049469
jak3
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
chr7_+_4474880 0.26 ENSDART00000143528
si:dkey-83f18.14
si:dkey-83f18.14
chr18_+_3037998 0.25 ENSDART00000185844
ENSDART00000162657
rps3
ribosomal protein S3
chr5_+_29794058 0.25 ENSDART00000045410
thy1
Thy-1 cell surface antigen
chr23_+_36095260 0.25 ENSDART00000127384
hoxc9a
homeobox C9a
chr12_-_28983584 0.25 ENSDART00000112374
zgc:171713
zgc:171713
chr5_+_6670945 0.25 ENSDART00000185686
pxna
paxillin a
chr6_+_28877306 0.25 ENSDART00000065137
ENSDART00000123189
ENSDART00000065135
ENSDART00000181512
ENSDART00000130799
tp63
tumor protein p63
chr11_+_11303458 0.24 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
si:dkey-23f9.4
chr10_-_22127942 0.24 ENSDART00000133374
ponzr2
plac8 onzin related protein 2
chr3_-_32071468 0.24 ENSDART00000121979
BX511080.1

chr16_-_9694822 0.24 ENSDART00000168748
COLEC10
si:ch211-93i7.4
chr11_-_30634286 0.24 ENSDART00000191019
zgc:153665
zgc:153665
chr10_+_40629616 0.24 ENSDART00000147476
CR396590.9

chr13_+_829585 0.23 ENSDART00000029051
gsta.2
glutathione S-transferase, alpha tandem duplicate 2
chr11_+_18130300 0.23 ENSDART00000169146
zgc:175135
zgc:175135
chr13_-_50139916 0.23 ENSDART00000099475
nid1a
nidogen 1a
chr3_-_29928695 0.23 ENSDART00000151275
ENSDART00000151083
grna
granulin a
chr5_+_27897504 0.23 ENSDART00000130936
adam28
ADAM metallopeptidase domain 28
chr13_-_11984867 0.23 ENSDART00000157538
npm3
nucleophosmin/nucleoplasmin, 3
chr12_-_46112892 0.23 ENSDART00000187128
ENSDART00000114268
zgc:153932
zgc:153932
chr11_+_18157260 0.23 ENSDART00000144659
zgc:173545
zgc:173545
chr2_+_50999477 0.23 ENSDART00000190111
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr5_-_30615901 0.22 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr6_+_41191482 0.22 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr17_-_20118145 0.22 ENSDART00000149737
ENSDART00000165606
ryr2b
ryanodine receptor 2b (cardiac)
chr6_-_7720332 0.22 ENSDART00000135945
rpsa
ribosomal protein SA
chr19_+_43297546 0.22 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr16_-_7443388 0.22 ENSDART00000017445
prdm1a
PR domain containing 1a, with ZNF domain
chr10_-_44560165 0.22 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr22_+_3156386 0.22 ENSDART00000161212
rpl36
ribosomal protein L36
chr21_-_11654422 0.21 ENSDART00000081614
ENSDART00000132699
cast
calpastatin
chr7_+_17443567 0.21 ENSDART00000060383
nitr2b
novel immune-type receptor 2b
chr23_+_19813677 0.21 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr20_-_23426339 0.21 ENSDART00000004625
zar1
zygote arrest 1
chr24_-_10006158 0.21 ENSDART00000106244
zgc:171750
zgc:171750
chr11_-_40457325 0.21 ENSDART00000128442
tnfrsf1b
tumor necrosis factor receptor superfamily, member 1B
chr23_+_32029304 0.21 ENSDART00000185217
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr17_-_30635298 0.21 ENSDART00000155478
sh3yl1
SH3 and SYLF domain containing 1
chr10_+_29840725 0.21 ENSDART00000127268
BX120005.1

chr15_-_951118 0.21 ENSDART00000171427
alox5b.1
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr22_-_10541372 0.20 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr11_+_13166750 0.20 ENSDART00000169961
mob3c
MOB kinase activator 3C
chr22_-_14272699 0.20 ENSDART00000190121
si:ch211-246m6.5
si:ch211-246m6.5
chr1_-_56032619 0.20 ENSDART00000143793
c3a.4
complement component c3a, duplicate 4
chr16_-_26731928 0.20 ENSDART00000135860
rnf41l
ring finger protein 41, like
chr7_+_17816006 0.20 ENSDART00000080834
eml3
echinoderm microtubule associated protein like 3
chr10_-_7785930 0.20 ENSDART00000043961
ENSDART00000111058
mpx
myeloid-specific peroxidase
chr20_+_26880668 0.20 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr22_-_20695237 0.20 ENSDART00000112722
org
oogenesis-related gene
chr9_-_6991650 0.19 ENSDART00000081718
slc9a2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr5_-_69620722 0.19 ENSDART00000097248
aldh2.2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr23_-_19230627 0.19 ENSDART00000007122
guca1b
guanylate cyclase activator 1B
chr4_-_17669881 0.19 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr15_+_22394074 0.19 ENSDART00000109931
oafa
OAF homolog a (Drosophila)
chr1_-_18811517 0.19 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr18_+_9171778 0.19 ENSDART00000101192
sema3d
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr14_-_32884138 0.19 ENSDART00000105726
slc25a5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr21_-_17296789 0.19 ENSDART00000192180
gfi1b
growth factor independent 1B transcription repressor
chr21_+_11560153 0.19 ENSDART00000065842
cd8a
CD8a molecule
chr17_-_23616626 0.19 ENSDART00000104730
ifit14
interferon-induced protein with tetratricopeptide repeats 14
chr17_+_16046314 0.19 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr22_+_31039091 0.19 ENSDART00000060005
rpl32
ribosomal protein L32
chr23_+_9220436 0.18 ENSDART00000033663
ENSDART00000139870
rps21
ribosomal protein S21
chr5_-_72390259 0.18 ENSDART00000172302
wbp1
WW domain binding protein 1
chr9_+_23714406 0.18 ENSDART00000189445
gypc
glycophorin C (Gerbich blood group)
chr11_-_40519886 0.18 ENSDART00000172819
miip
migration and invasion inhibitory protein
chr24_-_25166720 0.18 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr17_+_43867889 0.18 ENSDART00000132673
ENSDART00000167214
zgc:66313
zgc:66313
chr25_-_16724913 0.18 ENSDART00000157075
galnt8a.2
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 2
chr16_+_41826584 0.18 ENSDART00000147523
si:dkey-199f5.6
si:dkey-199f5.6
chr20_+_2039518 0.18 ENSDART00000043157
CABZ01088134.1

chr16_+_42471455 0.18 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr22_+_19538626 0.18 ENSDART00000189174
BX936298.2

chr7_-_20158380 0.18 ENSDART00000142891
acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr9_-_21912227 0.18 ENSDART00000145576
lmo7a
LIM domain 7a
chr9_+_1313418 0.18 ENSDART00000191361
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr18_-_25568994 0.18 ENSDART00000133029
si:ch211-13k12.2
si:ch211-13k12.2
chr16_+_26732086 0.18 ENSDART00000138496
rad54b
RAD54 homolog B (S. cerevisiae)
chr16_-_48430272 0.18 ENSDART00000005927
rad21a
RAD21 cohesin complex component a
chr2_-_55779927 0.18 ENSDART00000168579
CABZ01066725.1

chr14_+_26247319 0.17 ENSDART00000192793
CCDC69
coiled-coil domain containing 69
chr6_+_39098397 0.17 ENSDART00000003716
ENSDART00000188655
prss60.2
protease, serine, 60.2
chr6_+_19948043 0.17 ENSDART00000182636
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr13_+_835390 0.17 ENSDART00000171329
gsta.1
glutathione S-transferase, alpha tandem duplicate 1
chr12_-_11349899 0.17 ENSDART00000079645
zgc:174164
zgc:174164
chr18_+_29898955 0.17 ENSDART00000064080
cenpn
centromere protein N
chr25_+_15939275 0.17 ENSDART00000126641
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr2_-_45510699 0.17 ENSDART00000024034
ENSDART00000145634
gpsm2
G protein signaling modulator 2
chr5_+_9246018 0.17 ENSDART00000081769
ENSDART00000183189
susd1
sushi domain containing 1
chr2_-_49985351 0.17 ENSDART00000145888
ccr12a
chemokine (C-C motif) receptor 12a
chr18_-_18942098 0.17 ENSDART00000100458
si:dkey-73n10.1
si:dkey-73n10.1
chr24_-_34680956 0.17 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr11_-_44801968 0.17 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr9_-_24031461 0.17 ENSDART00000021218
rpe
ribulose-5-phosphate-3-epimerase
chr8_-_7847921 0.17 ENSDART00000188094
zgc:113363
zgc:113363
chr21_+_382400 0.17 ENSDART00000190785
ENSDART00000124615
rad23b
RAD23 homolog B, nucleotide excision repair protein
chr19_+_5640504 0.16 ENSDART00000179987
ft2
alpha(1,3)fucosyltransferase gene 2
chr8_-_24252933 0.16 ENSDART00000057624
zgc:110353
zgc:110353
chr21_-_19919020 0.16 ENSDART00000147396
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr3_+_26244353 0.16 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr20_-_33675676 0.16 ENSDART00000147168
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr7_-_64971839 0.16 ENSDART00000164682
sinhcafl
SIN3-HDAC complex associated factor, like
chr4_-_77218637 0.16 ENSDART00000174325
psmb10
proteasome subunit beta 10
chr22_+_1092479 0.16 ENSDART00000170119
guca1e
guanylate cyclase activator 1e
chr18_-_34549721 0.16 ENSDART00000137101
ENSDART00000021880
ssr3
signal sequence receptor, gamma
chr5_+_61998641 0.16 ENSDART00000137110
selenow1
selenoprotein W, 1
chr19_-_20403507 0.16 ENSDART00000052603
ENSDART00000137590
dazl
deleted in azoospermia-like
chr8_+_45334255 0.16 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr11_+_25539698 0.16 ENSDART00000035602
cxxc1b
CXXC finger protein 1b
chr8_+_41037541 0.15 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr11_+_24716837 0.15 ENSDART00000145217
zgc:153953
zgc:153953
chr7_-_20464468 0.15 ENSDART00000134700
cnpy4
canopy4
chr4_+_9508505 0.15 ENSDART00000080842
kitlgb
kit ligand b
chr8_-_46486009 0.15 ENSDART00000140431
sult1st9
sulfotransferase family 1, cytosolic sulfotransferase 9
chr25_-_18435481 0.15 ENSDART00000004771
poc1b
POC1 centriolar protein B
chr7_+_38510197 0.15 ENSDART00000173468
ENSDART00000100479
slc7a9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr21_+_25236297 0.15 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr19_+_11217279 0.15 ENSDART00000181859
si:ch73-109i22.2
si:ch73-109i22.2
chr19_-_20403845 0.15 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr3_+_5490104 0.15 ENSDART00000170191
FQ311879.1

chr9_+_21165017 0.15 ENSDART00000145933
ENSDART00000142985
si:rp71-68n21.9
si:rp71-68n21.9
chr13_-_40401870 0.15 ENSDART00000128951
nkx3.3
NK3 homeobox 3
chr18_+_27300700 0.15 ENSDART00000140444
plekha7a
pleckstrin homology domain containing, family A member 7a
chr16_+_50972803 0.15 ENSDART00000178189
si:dkeyp-97a10.2
si:dkeyp-97a10.2
chr7_-_7972445 0.15 ENSDART00000182687
ENSDART00000191946
si:cabz01030277.1
si:cabz01030277.1
chr22_+_31025096 0.15 ENSDART00000185953
zmp:0000000735
zmp:0000000735
chr7_+_2236317 0.15 ENSDART00000075859
zgc:172065
zgc:172065
chr22_+_30543437 0.15 ENSDART00000137983
si:dkey-103k4.1
si:dkey-103k4.1
chr1_+_513986 0.15 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr1_+_40801696 0.15 ENSDART00000147497
cpz
carboxypeptidase Z
chr2_+_3201345 0.14 ENSDART00000130349
wnt9a
wingless-type MMTV integration site family, member 9A
chr9_+_30475563 0.14 ENSDART00000133118
gja5a
gap junction protein, alpha 5a
chr17_-_31695217 0.14 ENSDART00000104332
ENSDART00000143090
lin52
lin-52 DREAM MuvB core complex component
chr24_+_36414829 0.14 ENSDART00000062699
si:ch211-253b1.3
si:ch211-253b1.3
chr3_+_22381955 0.14 ENSDART00000185315
arhgap27l
Rho GTPase activating protein 27, like
chr14_+_23709134 0.14 ENSDART00000191162
ENSDART00000179754
ENSDART00000054266
gnpda1
glucosamine-6-phosphate deaminase 1
chr8_+_22472584 0.14 ENSDART00000138303
si:dkey-23c22.9
si:dkey-23c22.9
chr9_-_35633827 0.14 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr5_+_29652513 0.14 ENSDART00000035400
tsc1a
TSC complex subunit 1a
chr3_+_31093455 0.14 ENSDART00000153074
si:dkey-66i24.9
si:dkey-66i24.9
chr18_-_26894732 0.14 ENSDART00000147735
ENSDART00000188938
BX470164.1
si:dkey-24l11.2

si:dkey-24l11.2
chr24_+_12835935 0.14 ENSDART00000114762
nanog
nanog homeobox
chr24_-_28245872 0.14 ENSDART00000167861
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr4_+_28997595 0.14 ENSDART00000133357
si:dkey-13e3.1
si:dkey-13e3.1
chr6_-_10927766 0.13 ENSDART00000134327
ccr7
chemokine (C-C motif) receptor 7
chr3_+_27798094 0.13 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr21_+_26657404 0.13 ENSDART00000129035
ENSDART00000186550
prdx5
peroxiredoxin 5
chr17_+_22530820 0.13 ENSDART00000089916
edaradd
EDAR-associated death domain
chr19_+_7045033 0.13 ENSDART00000146579
mhc1uka
major histocompatibility complex class I UKA
chr18_+_19120984 0.13 ENSDART00000141501
si:dkey-242h9.3
si:dkey-242h9.3
chr2_+_16780643 0.13 ENSDART00000125647
ENSDART00000108611
ENSDART00000181245
ENSDART00000163194
tfa
transferrin-a
chr3_-_42125655 0.13 ENSDART00000040753
nudt1
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr19_+_31904836 0.13 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr9_-_10778615 0.13 ENSDART00000182577
CABZ01053619.1

chr17_+_16046132 0.13 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr3_+_39663987 0.13 ENSDART00000184614
ENSDART00000184573
ENSDART00000183127
epn2
epsin 2
chr6_+_42475730 0.13 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr15_+_24795473 0.13 ENSDART00000139689
ENSDART00000141033
ENSDART00000100746
ENSDART00000135677
gosr1
golgi SNAP receptor complex member 1
chr10_-_17988779 0.13 ENSDART00000132206
ENSDART00000144841
si:dkey-242g16.2
si:dkey-242g16.2
chr9_-_53666031 0.13 ENSDART00000126314
pcdh8
protocadherin 8

Network of associatons between targets according to the STRING database.

First level regulatory network of barhl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.3 GO:0051000 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.1 0.2 GO:0019323 pentose catabolic process(GO:0019323)
0.1 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.2 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.3 GO:0030101 natural killer cell activation(GO:0030101)
0.1 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.3 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.0 0.2 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996) positive regulation of Golgi to plasma membrane protein transport(GO:0042998) regulation of establishment of protein localization to plasma membrane(GO:0090003) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.2 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.1 GO:0045226 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.0 0.1 GO:0006178 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.2 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.2 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.3 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.3 GO:0045453 bone resorption(GO:0045453)
0.0 0.8 GO:0042743 hydrogen peroxide metabolic process(GO:0042743)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.0 0.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.0 0.1 GO:0072679 chemokine production(GO:0032602) negative T cell selection(GO:0043383) thymocyte migration(GO:0072679)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.0 0.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.2 GO:0006971 hypotonic response(GO:0006971) hypotonic salinity response(GO:0042539)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.2 GO:0001709 cell fate determination(GO:0001709)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957) lateral line ganglion development(GO:0048890)
0.0 0.1 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.0 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.2 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.0 GO:0022626 cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626)
0.0 0.1 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.3 GO:0043186 P granule(GO:0043186)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.3 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.2 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.4 GO:0030250 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.0 0.1 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0015217 ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell