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PRJNA207719: Tissue specific transcriptome profiling

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Results for barx2

Z-value: 1.11

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Transcription factors associated with barx2

Gene Symbol Gene ID Gene Info
barx2
ENSDARG00000041098 BARX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barx2dr11_v1_chr18_+_47313715_47313715-0.128.5e-01Click!

Activity profile of barx2 motif

Sorted Z-values of barx2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_9669717 1.83 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr9_-_9348058 0.93 ENSDART00000132257
zgc:113337
zgc:113337
chr11_+_30057762 0.92 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr19_-_26869103 0.91 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr12_+_18578597 0.87 ENSDART00000134944
grid2ipb
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr23_+_40460333 0.86 ENSDART00000184658
soga3b
SOGA family member 3b
chr16_+_5774977 0.86 ENSDART00000134202
ccka
cholecystokinin a
chr5_+_63668735 0.82 ENSDART00000134261
ENSDART00000097330
dnm1b
dynamin 1b
chr22_-_13851297 0.76 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr9_+_7998794 0.75 ENSDART00000138167
myo16
myosin XVI
chr2_-_44280061 0.74 ENSDART00000136818
mpz
myelin protein zero
chr2_+_20430366 0.71 ENSDART00000155108
si:ch211-153l6.6
si:ch211-153l6.6
chr15_+_15856178 0.70 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr9_+_54039006 0.69 ENSDART00000112441
tlr7
toll-like receptor 7
chr17_-_200316 0.69 ENSDART00000190561
CABZ01083778.1

chr14_-_30587814 0.68 ENSDART00000144912
ENSDART00000149714
tmem265
transmembrane protein 265
chr20_+_41756996 0.68 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr6_-_11768198 0.67 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr16_-_28856112 0.66 ENSDART00000078543
syt11b
synaptotagmin XIb
chr8_+_31717175 0.65 ENSDART00000013434
oxct1a
3-oxoacid CoA transferase 1a
chr25_-_19420949 0.64 ENSDART00000181338
map1ab
microtubule-associated protein 1Ab
chr8_-_50888806 0.64 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr12_-_10300101 0.62 ENSDART00000126428
mpp2b
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr21_-_20939488 0.62 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr12_+_1139690 0.61 ENSDART00000160442
CABZ01072885.1

chr20_-_47188966 0.61 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr15_-_44512461 0.59 ENSDART00000155456
gria4a
glutamate receptor, ionotropic, AMPA 4a
chr12_+_48480632 0.59 ENSDART00000158157
arhgap44
Rho GTPase activating protein 44
chr9_-_42418470 0.57 ENSDART00000144353
calcrla
calcitonin receptor-like a
chr8_+_31716872 0.57 ENSDART00000161121
oxct1a
3-oxoacid CoA transferase 1a
chr25_+_37126921 0.56 ENSDART00000124331
si:ch1073-174d20.1
si:ch1073-174d20.1
chr11_+_30663300 0.56 ENSDART00000161662
ttbk1a
tau tubulin kinase 1a
chr6_+_13933464 0.55 ENSDART00000109144
ptprnb
protein tyrosine phosphatase, receptor type, Nb
chr6_-_6487876 0.54 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr17_-_20717845 0.54 ENSDART00000150037
ank3b
ankyrin 3b
chr16_+_46111849 0.54 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr7_+_73397283 0.53 ENSDART00000174390
CABZ01081780.1

chr5_+_4054704 0.53 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr4_+_17279966 0.53 ENSDART00000067005
ENSDART00000137487
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr23_-_26521970 0.52 ENSDART00000143712
si:dkey-205h13.1
si:dkey-205h13.1
chr4_-_5019113 0.51 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr10_-_21054059 0.51 ENSDART00000139733
pcdh1a
protocadherin 1a
chr2_+_29491314 0.51 ENSDART00000181774
dlgap1a
discs, large (Drosophila) homolog-associated protein 1a
chr16_-_25568512 0.51 ENSDART00000149411
atxn1b
ataxin 1b
chr10_+_45089820 0.51 ENSDART00000175481
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr3_-_20040636 0.48 ENSDART00000104118
atxn7l3
ataxin 7-like 3
chr22_+_18816662 0.48 ENSDART00000132476
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr18_+_24919614 0.47 ENSDART00000008638
rgma
repulsive guidance molecule family member a
chr23_-_36857964 0.46 ENSDART00000188822
ENSDART00000134061
ENSDART00000093061
hipk1a
homeodomain interacting protein kinase 1a
chr8_+_26141680 0.46 ENSDART00000078334
celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr24_-_28437833 0.45 ENSDART00000125412
fbxo45
F-box protein 45
chr2_+_7295515 0.44 ENSDART00000152987
si:dkeyp-106c3.1
si:dkeyp-106c3.1
chr22_-_26865361 0.44 ENSDART00000182504
hmox2a
heme oxygenase 2a
chr13_-_29420885 0.44 ENSDART00000024225
chata
choline O-acetyltransferase a
chr6_-_29305132 0.43 ENSDART00000132456
bivm
basic, immunoglobulin-like variable motif containing
chr16_+_54209504 0.43 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr5_-_6377865 0.43 ENSDART00000031775
zgc:73226
zgc:73226
chr7_-_25895189 0.43 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr16_-_35329803 0.43 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr15_+_15516612 0.42 ENSDART00000016024
traf4a
tnf receptor-associated factor 4a
chr5_-_42661012 0.42 ENSDART00000158339
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr16_-_12173399 0.42 ENSDART00000142574
clstn3
calsyntenin 3
chr3_-_48716422 0.42 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr17_-_39779906 0.42 ENSDART00000155181
pimr61
Pim proto-oncogene, serine/threonine kinase, related 61
chr20_+_34717403 0.42 ENSDART00000034252
pnocb
prepronociceptin b
chr14_-_470505 0.42 ENSDART00000067147
ANKRD50
ankyrin repeat domain 50
chr3_+_46459540 0.41 ENSDART00000188150
si:ch211-66e2.5
si:ch211-66e2.5
chr3_-_40054615 0.41 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr18_-_48983690 0.41 ENSDART00000182359
FO681288.3

chr8_-_14375890 0.40 ENSDART00000090306
xpr1a
xenotropic and polytropic retrovirus receptor 1a
chr5_+_65536095 0.40 ENSDART00000189898
si:dkey-21e5.1
si:dkey-21e5.1
chr6_-_30210378 0.40 ENSDART00000157359
ENSDART00000113924
lrrc7
leucine rich repeat containing 7
chr12_+_4971515 0.40 ENSDART00000161076
arhgap27
Rho GTPase activating protein 27
chr23_+_17899226 0.39 ENSDART00000079487
CU234171.1

chr15_-_9257136 0.39 ENSDART00000187901
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr5_-_66702479 0.39 ENSDART00000129197
mn1b
meningioma 1b
chr5_+_42400777 0.38 ENSDART00000183114
BX548073.8

chr7_-_49594995 0.38 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr17_-_39772999 0.38 ENSDART00000155727
pimr60
Pim proto-oncogene, serine/threonine kinase, related 60
chr2_-_3678029 0.38 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr6_-_40744720 0.38 ENSDART00000154916
ENSDART00000186922
p4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr12_+_8168272 0.38 ENSDART00000054092
arid5b
AT-rich interaction domain 5B
chr4_+_4849789 0.37 ENSDART00000130818
ENSDART00000127751
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr10_-_2524917 0.37 ENSDART00000188642
CU856539.1

chr21_-_28340977 0.37 ENSDART00000141629
nrxn2a
neurexin 2a
chr19_-_42045372 0.36 ENSDART00000144275
trioa
trio Rho guanine nucleotide exchange factor a
chr21_+_32820175 0.36 ENSDART00000076903
adra2db
adrenergic, alpha-2D-, receptor b
chr16_-_12173554 0.36 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr21_-_39177564 0.36 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr5_-_14373662 0.36 ENSDART00000183694
tet3
tet methylcytosine dioxygenase 3
chr5_-_12407194 0.36 ENSDART00000125291
ksr2
kinase suppressor of ras 2
chr25_-_27722614 0.36 ENSDART00000190154
zgc:153935
zgc:153935
chr10_-_43404027 0.35 ENSDART00000086227
edil3b
EGF-like repeats and discoidin I-like domains 3b
chr16_-_34212912 0.35 ENSDART00000145017
phactr4b
phosphatase and actin regulator 4b
chr4_-_2219705 0.35 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr7_+_19552381 0.34 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr10_-_2524297 0.34 ENSDART00000192475
CU856539.1

chr23_+_4253957 0.34 ENSDART00000008761
arl6ip5b
ADP-ribosylation factor-like 6 interacting protein 5b
chr21_+_723998 0.34 ENSDART00000160956
oaz1b
ornithine decarboxylase antizyme 1b
chr1_-_50859053 0.34 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr11_-_1509773 0.34 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr20_+_40457599 0.34 ENSDART00000017553
serinc1
serine incorporator 1
chr21_+_13383413 0.34 ENSDART00000151345
zgc:113162
zgc:113162
chr10_-_7857494 0.34 ENSDART00000143215
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr21_+_13387965 0.34 ENSDART00000134347
zgc:113162
zgc:113162
chr15_-_14552101 0.34 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr1_+_6862917 0.33 ENSDART00000182953
erbb4a
erb-b2 receptor tyrosine kinase 4a
chr1_-_39909985 0.33 ENSDART00000181673
stox2a
storkhead box 2a
chr8_+_23521974 0.33 ENSDART00000188130
ENSDART00000129378
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr15_-_755023 0.33 ENSDART00000155594
znf1011
zinc finger protein 1011
chr18_+_17725410 0.33 ENSDART00000090608
rspry1
ring finger and SPRY domain containing 1
chr25_+_16098620 0.33 ENSDART00000142564
ENSDART00000165598
far1
fatty acyl CoA reductase 1
chr2_+_57848844 0.33 ENSDART00000037279
plekhj1
pleckstrin homology domain containing, family J member 1
chr25_+_16116740 0.33 ENSDART00000139778
far1
fatty acyl CoA reductase 1
chr1_+_38775041 0.33 ENSDART00000110824
wdr17
WD repeat domain 17
chr15_-_47115787 0.32 ENSDART00000192601
CABZ01079081.1

chr13_+_7292061 0.32 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr1_-_47071979 0.32 ENSDART00000160817
itsn1
intersectin 1 (SH3 domain protein)
chr20_-_48027526 0.32 ENSDART00000154729
gareml
GRB2 associated, regulator of MAPK1-like
chr25_-_25058508 0.32 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr10_-_26766780 0.32 ENSDART00000146666
mcf2b
MCF.2 cell line derived transforming sequence b
chr5_+_42379517 0.32 ENSDART00000103325
pimr59
Pim proto-oncogene, serine/threonine kinase, related 59
chr13_+_15656042 0.32 ENSDART00000134240
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr1_+_51312752 0.32 ENSDART00000063938
mast1a
microtubule associated serine/threonine kinase 1a
chr8_+_52637507 0.31 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr5_+_42386705 0.31 ENSDART00000143034
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr5_+_42407962 0.31 ENSDART00000188489
BX548073.11

chr16_+_40024883 0.31 ENSDART00000110100
hint3
histidine triad nucleotide binding protein 3
chr2_-_30784198 0.31 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr24_+_3478871 0.31 ENSDART00000111491
ENSDART00000134598
ENSDART00000142407
wdr37
WD repeat domain 37
chr2_-_23004286 0.30 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr11_+_11267493 0.30 ENSDART00000148425
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr19_-_3931917 0.30 ENSDART00000162532
map7d1b
MAP7 domain containing 1b
chr1_-_46981134 0.30 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr2_-_33645411 0.30 ENSDART00000114663
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr7_-_48805181 0.30 ENSDART00000015884
mfge8a
milk fat globule-EGF factor 8 protein a
chr16_-_44945224 0.30 ENSDART00000156921
ncam3
neural cell adhesion molecule 3
chr10_+_42423318 0.29 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr16_-_32837806 0.29 ENSDART00000003997
MCHR2
si:dkey-165n16.5
chr23_+_32021803 0.29 ENSDART00000012963
trappc6b
trafficking protein particle complex 6b
chr16_-_22781446 0.28 ENSDART00000144107
lenep
lens epithelial protein
chr17_-_11329959 0.28 ENSDART00000015418
irf2bpl
interferon regulatory factor 2 binding protein-like
chr11_-_33857911 0.28 ENSDART00000165370
nxph2b
neurexophilin 2b
chr1_-_15797663 0.28 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr7_+_20629411 0.28 ENSDART00000173710
si:dkey-19b23.15
si:dkey-19b23.15
chr23_-_36303216 0.28 ENSDART00000188720
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr7_-_71829649 0.28 ENSDART00000160449
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr24_-_15131831 0.28 ENSDART00000028410
cd226
CD226 molecule
chr5_+_42393896 0.27 ENSDART00000189550
BX548073.13

chr17_-_2386569 0.27 ENSDART00000121614
PLCB2
phospholipase C beta 2
chr23_-_900795 0.27 ENSDART00000190517
ENSDART00000182849
ENSDART00000111456
ENSDART00000185430
rbm10
RNA binding motif protein 10
chr20_-_53078607 0.27 ENSDART00000163494
ENSDART00000191730
CABZ01066813.1

chr10_-_36927594 0.27 ENSDART00000162046
sez6a
seizure related 6 homolog a
chr3_+_62339264 0.27 ENSDART00000174569
BX470259.3

chr1_+_45663727 0.27 ENSDART00000038574
ENSDART00000141144
ENSDART00000149565
trappc5
trafficking protein particle complex 5
chr2_+_6127593 0.27 ENSDART00000184007
fzr1b
fizzy/cell division cycle 20 related 1b
chr10_-_20339113 0.26 ENSDART00000144378
ENSDART00000098600
zmat4b
zinc finger, matrin-type 4b
chr15_-_18162647 0.26 ENSDART00000012064
pih1d2
PIH1 domain containing 2
chr3_+_24190207 0.26 ENSDART00000034762
prr15la
proline rich 15-like a
chr25_-_29988352 0.26 ENSDART00000067059
fam19a5b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr10_+_15967643 0.26 ENSDART00000136709
apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr19_-_205104 0.26 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr1_-_19502322 0.25 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr8_+_44722140 0.25 ENSDART00000163381
elmod3
ELMO/CED-12 domain containing 3
chr2_+_11923615 0.25 ENSDART00000126118
trove2
TROVE domain family, member 2
chr1_-_22512063 0.25 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr8_+_7097929 0.25 ENSDART00000188955
ENSDART00000184772
ENSDART00000109581
abtb1
ankyrin repeat and BTB (POZ) domain containing 1
chr7_+_48805534 0.24 ENSDART00000145375
ENSDART00000148744
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr4_-_75158035 0.24 ENSDART00000174353
CABZ01066312.1

chr5_-_55933420 0.24 ENSDART00000050966
slc25a46
solute carrier family 25, member 46
chr22_-_27113332 0.24 ENSDART00000146951
ENSDART00000178855
xpnpep1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr20_-_5052786 0.24 ENSDART00000138818
ENSDART00000181655
ENSDART00000164274
arid1b
AT rich interactive domain 1B (SWI1-like)
chr18_+_3579829 0.23 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr4_+_2482046 0.23 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr6_+_49551614 0.23 ENSDART00000022581
rab22a
RAB22A, member RAS oncogene family
chr19_+_1673599 0.23 ENSDART00000163127
klhl7
kelch-like family member 7
chr21_+_21195487 0.23 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr7_+_48805725 0.22 ENSDART00000166543
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr14_-_28534563 0.22 ENSDART00000054088
zgc:113364
zgc:113364
chr6_-_1432200 0.22 ENSDART00000182901
LO018148.1

chr22_+_2769236 0.22 ENSDART00000141836
si:dkey-20i20.10
si:dkey-20i20.10
chr9_+_2574122 0.22 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr19_+_40069524 0.22 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr6_-_40466861 0.22 ENSDART00000062724
crbn
cereblon
chr1_+_11977426 0.22 ENSDART00000103399
tspan5b
tetraspanin 5b
chr22_-_18179214 0.21 ENSDART00000129576
si:ch211-125m10.6
si:ch211-125m10.6
chr10_-_17587832 0.21 ENSDART00000113101
smarcad1b
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 b
chr8_-_7567815 0.21 ENSDART00000132536
hcfc1b
host cell factor C1b
chr22_-_21897203 0.21 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr21_+_27513859 0.21 ENSDART00000065420
pacs1a
phosphofurin acidic cluster sorting protein 1a
chr8_+_28358161 0.21 ENSDART00000062682
adipor1b
adiponectin receptor 1b
chr11_-_27867024 0.21 ENSDART00000182136
ENSDART00000187587
eif4g3a
eukaryotic translation initiation factor 4 gamma, 3a
chr19_+_14351560 0.21 ENSDART00000182732
arid1ab
AT rich interactive domain 1Ab (SWI-like)
chr23_-_35790235 0.21 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
mfsd5
major facilitator superfamily domain containing 5
chr8_-_19246342 0.20 ENSDART00000147172
abhd17ab
abhydrolase domain containing 17Ab
chr7_-_31922432 0.20 ENSDART00000188398
lin7c
lin-7 homolog C (C. elegans)
chr4_-_908821 0.20 ENSDART00000168266
mrap2b
melanocortin 2 receptor accessory protein 2b
chr3_-_15999501 0.20 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr12_+_32323098 0.20 ENSDART00000188722
ANKFN1
si:ch211-277e21.2
chr12_-_7854216 0.20 ENSDART00000149594
ank3b
ankyrin 3b

Network of associatons between targets according to the STRING database.

First level regulatory network of barx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 0.7 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.4 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.5 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.6 GO:0000012 single strand break repair(GO:0000012)
0.1 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.4 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.3 GO:0002833 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 0.4 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.4 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.5 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.1 0.2 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.2 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.4 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.0 0.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.4 GO:0043584 nose development(GO:0043584)
0.0 0.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.5 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.4 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.0 0.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.2 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.2 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.6 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.5 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.1 GO:1903430 negative regulation of cell maturation(GO:1903430)
0.0 1.3 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.4 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 0.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0090317 negative regulation of intracellular transport(GO:0032387) intraciliary transport involved in cilium morphogenesis(GO:0035735) negative regulation of intracellular protein transport(GO:0090317)
0.0 0.2 GO:0090148 membrane fission(GO:0090148)
0.0 0.6 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.3 GO:0001881 receptor recycling(GO:0001881)
0.0 0.6 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.9 GO:0007586 digestion(GO:0007586)
0.0 0.3 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0070207 protein trimerization(GO:0070206) protein homotrimerization(GO:0070207)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.8 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.6 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.8 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.0 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0021767 mammillary body development(GO:0021767)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0060021 palate development(GO:0060021)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.3 GO:0097255 R2TP complex(GO:0097255)
0.1 0.3 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.4 GO:0035060 brahma complex(GO:0035060)
0.1 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.7 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.8 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 2.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0070449 elongin complex(GO:0070449)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0030141 secretory granule(GO:0030141)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.6 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.7 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.5 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.3 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.2 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.3 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.7 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair