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PRJNA207719: Tissue specific transcriptome profiling

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Results for bcl6aa+bcl6ab+bcl6b

Z-value: 1.02

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Transcription factors associated with bcl6aa+bcl6ab+bcl6b

Gene Symbol Gene ID Gene Info
bcl6ab
ENSDARG00000069295 BCL6A transcription repressor b
bcl6b
ENSDARG00000069335 BCL6B transcription repressor
bcl6aa
ENSDARG00000070864 BCL6A transcription repressor a
bcl6aa
ENSDARG00000111395 BCL6A transcription repressor a
bcl6aa
ENSDARG00000112502 BCL6A transcription repressor a
bcl6aa
ENSDARG00000116260 BCL6A transcription repressor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bcl6adr11_v1_chr6_-_28222592_28222592-0.791.1e-01Click!
bcl6bdr11_v1_chr7_+_20019125_20019125-0.751.4e-01Click!
bcl6abdr11_v1_chr2_-_10098191_10098191-0.454.4e-01Click!

Activity profile of bcl6aa+bcl6ab+bcl6b motif

Sorted Z-values of bcl6aa+bcl6ab+bcl6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_-_17395315 0.79 ENSDART00000064596
cyp2x8
cytochrome P450, family 2, subfamily X, polypeptide 8
chr16_-_36834505 0.76 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
pnp4b
purine nucleoside phosphorylase 4b
chr14_+_11457500 0.74 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr5_-_63509581 0.72 ENSDART00000097325
c5
complement component 5
chr2_-_10703621 0.66 ENSDART00000005944
rpl5a
ribosomal protein L5a
chr16_-_45917322 0.65 ENSDART00000060822
afp4
antifreeze protein type IV
chr3_+_19299309 0.62 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr11_-_8167799 0.62 ENSDART00000133574
ENSDART00000024046
ENSDART00000146940
uox
urate oxidase
chr20_+_23440632 0.59 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr19_-_5351980 0.57 ENSDART00000163304
ENSDART00000027701
krt92
keratin 92
chr21_-_26114886 0.52 ENSDART00000139320
nipal4
NIPA-like domain containing 4
chr6_+_41503854 0.51 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr12_-_4243268 0.50 ENSDART00000131275
zgc:92313
zgc:92313
chr3_-_57737913 0.50 ENSDART00000113309
LGALS3BP (1 of many)
zgc:112492
chr3_-_44059902 0.46 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr5_+_29794058 0.45 ENSDART00000045410
thy1
Thy-1 cell surface antigen
chr8_+_1189798 0.44 ENSDART00000193474
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr2_-_38284648 0.43 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
si:ch211-14a17.7
chr5_+_28849155 0.43 ENSDART00000079090
zgc:174259
zgc:174259
chr22_+_25289360 0.42 ENSDART00000143782
si:ch211-154a22.8
si:ch211-154a22.8
chr25_-_29415369 0.42 ENSDART00000110774
ENSDART00000019183
ugt5a2
ugt5a1
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr22_+_7480465 0.42 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr9_-_54304684 0.42 ENSDART00000109512
il13
interleukin 13
chr7_+_14005111 0.42 ENSDART00000187365
furina
furin (paired basic amino acid cleaving enzyme) a
chr9_+_20869166 0.41 ENSDART00000147892
wdr3
WD repeat domain 3
chr9_-_43644261 0.40 ENSDART00000023684
cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr6_-_8498908 0.39 ENSDART00000149222
pglyrp2
peptidoglycan recognition protein 2
chr6_-_8498676 0.38 ENSDART00000148627
pglyrp2
peptidoglycan recognition protein 2
chr15_+_20239141 0.37 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_32856907 0.36 ENSDART00000148232
rpl30
ribosomal protein L30
chr24_-_2829049 0.36 ENSDART00000164913
PPP1R3G
si:ch211-152c8.5
chr15_+_5321612 0.36 ENSDART00000174345
or113-1
odorant receptor, family A, subfamily 113, member 1
chr3_-_55139127 0.35 ENSDART00000115324
hbae1.3
hemoglobin, alpha embryonic 1.3
chr8_-_21091961 0.35 ENSDART00000100281
aldh9a1a.2
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2
chr21_-_27338639 0.34 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr7_-_19168375 0.33 ENSDART00000112447
il13ra1
interleukin 13 receptor, alpha 1
chr16_-_27749172 0.33 ENSDART00000145198
steap4
STEAP family member 4
chr5_+_28858345 0.32 ENSDART00000111180
si:ch211-186e20.2
si:ch211-186e20.2
chr20_-_23440955 0.31 ENSDART00000153386
slc10a4
solute carrier family 10, member 4
chr1_-_55008882 0.30 ENSDART00000083572
zgc:136864
zgc:136864
chr4_+_49322310 0.30 ENSDART00000184154
ENSDART00000167162
BX942819.1

chr17_+_10318071 0.30 ENSDART00000161844
foxa1
forkhead box A1
chr14_-_5678457 0.29 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr20_+_25581627 0.29 ENSDART00000030229
cyp2p9
cytochrome P450, family 2, subfamily P, polypeptide 9
chr25_+_11281970 0.28 ENSDART00000180094
AKAP13
si:dkey-187e18.1
chr4_-_18436899 0.28 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr5_+_1911814 0.28 ENSDART00000172233
si:ch73-55i23.1
si:ch73-55i23.1
chr16_+_40954481 0.28 ENSDART00000058587
gbp
glycogen synthase kinase binding protein
chr8_+_22359881 0.28 ENSDART00000187867
zgc:153631
zgc:153631
chr25_-_13408760 0.28 ENSDART00000154445
gins3
GINS complex subunit 3
chr4_+_12342173 0.27 ENSDART00000161518
pimr214
Pim proto-oncogene, serine/threonine kinase, related 214
chr6_+_9881093 0.27 ENSDART00000151558
MPP4 (1 of many)
si:ch211-222n4.6
chr7_+_12950507 0.27 ENSDART00000067629
ENSDART00000158004
saa
serum amyloid A
chr20_-_19858936 0.27 ENSDART00000161579
ptk2bb
protein tyrosine kinase 2 beta, b
chr21_+_26073104 0.27 ENSDART00000193273
rpl23a
ribosomal protein L23a
chr8_+_47099033 0.26 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr3_+_49021079 0.26 ENSDART00000162012
zgc:163083
zgc:163083
chr19_-_35428815 0.25 ENSDART00000169006
ENSDART00000003167
ak2
adenylate kinase 2
chr2_+_13710439 0.25 ENSDART00000155712
ebna1bp2
EBNA1 binding protein 2
chr23_-_19715799 0.25 ENSDART00000142072
ENSDART00000032744
ENSDART00000131860
rpl10
ribosomal protein L10
chr1_-_56596701 0.24 ENSDART00000133693
LO018605.1

chr13_-_37642890 0.24 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
si:dkey-188i13.9
chr17_-_12498096 0.24 ENSDART00000149551
ENSDART00000105215
ENSDART00000191207
emilin1b
elastin microfibril interfacer 1b
chr17_+_34206167 0.24 ENSDART00000136167
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr21_-_18982337 0.24 ENSDART00000147246
si:ch211-222n4.6
si:ch211-222n4.6
chr1_+_11736420 0.23 ENSDART00000140329
chst12b
carbohydrate (chondroitin 4) sulfotransferase 12b
chr4_-_13548806 0.23 ENSDART00000067155
il22
interleukin 22
chr1_-_9195629 0.23 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr11_-_287670 0.23 ENSDART00000035737
slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr18_-_14860435 0.23 ENSDART00000018502
mapk12a
mitogen-activated protein kinase 12a
chr20_-_33704753 0.23 ENSDART00000157427
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr18_-_21170264 0.23 ENSDART00000175265
BX571884.1

chr4_-_13518381 0.23 ENSDART00000067153
ifng1-1
interferon, gamma 1-1
chr4_+_57580303 0.22 ENSDART00000166492
ENSDART00000103025
ENSDART00000170786
il17ra1b
il17ra2
interleukin 17 receptor A1b
interleukin 17 receptor A2
chr22_+_26400519 0.22 ENSDART00000159839
ENSDART00000144585
capn8
calpain 8
chr5_-_41841675 0.22 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr21_+_12010505 0.22 ENSDART00000123522
aqp7
aquaporin 7
chr16_+_42772678 0.21 ENSDART00000155575
si:ch211-135n15.2
si:ch211-135n15.2
chr5_+_9360394 0.21 ENSDART00000124642
FP236810.2

chr9_+_1313418 0.21 ENSDART00000191361
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr11_+_14286160 0.21 ENSDART00000166236
si:ch211-262i1.3
si:ch211-262i1.3
chr14_-_6987649 0.21 ENSDART00000060990
eif4ebp3l
eukaryotic translation initiation factor 4E binding protein 3, like
chr3_+_3139240 0.21 ENSDART00000105014
si:dkey-30g5.1
si:dkey-30g5.1
chr16_+_46294337 0.21 ENSDART00000040769
nr2f5
nuclear receptor subfamily 2, group F, member 5
chr3_-_3703572 0.20 ENSDART00000111017
si:ch211-163m16.7
si:ch211-163m16.7
chr4_+_73215536 0.20 ENSDART00000174290
LO018260.2
Danio rerio protein NLRC3-like (LOC101883187), mRNA.
chr9_-_32813177 0.20 ENSDART00000012694
mxc
myxovirus (influenza virus) resistance C
chr17_-_50331351 0.20 ENSDART00000149294
otofb
otoferlin b
chr12_-_23365737 0.19 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr17_+_7522777 0.19 ENSDART00000184723
klhl10b.2
kelch-like family member 10b, tandem duplicate 2
chr4_+_37406676 0.19 ENSDART00000130981
si:ch73-134f24.1
si:ch73-134f24.1
chr4_-_12323228 0.19 ENSDART00000081089
il17ra1a
interleukin 17 receptor A1a
chr21_+_27297145 0.19 ENSDART00000146588
si:dkey-175m17.6
si:dkey-175m17.6
chr11_-_22303678 0.19 ENSDART00000159527
ENSDART00000159681
tfeb
transcription factor EB
chr25_-_34280080 0.19 ENSDART00000085251
gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_-_47782916 0.19 ENSDART00000063337
cdca8
cell division cycle associated 8
chr19_+_4038589 0.19 ENSDART00000169271
btr23
bloodthirsty-related gene family, member 23
chr15_-_3282220 0.19 ENSDART00000092942
slc25a15a
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr20_+_53521648 0.19 ENSDART00000139794
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr11_+_43375326 0.18 ENSDART00000130131
sult6b1
sulfotransferase family, cytosolic, 6b, member 1
chr13_+_33688474 0.18 ENSDART00000161465
CABZ01087953.1

chr9_-_370225 0.18 ENSDART00000163637
si:dkey-11f4.7
si:dkey-11f4.7
chr19_-_3244360 0.18 ENSDART00000142222
zgc:158445
zgc:158445
chr7_-_54320088 0.18 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr17_+_16046132 0.18 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr3_+_12861158 0.18 ENSDART00000171237
kcnj2b
potassium inwardly-rectifying channel, subfamily J, member 2b
chr22_-_15578402 0.17 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr17_-_30521043 0.17 ENSDART00000087111
itsn2b
intersectin 2b
chr21_-_22676323 0.17 ENSDART00000167392
gig2h
grass carp reovirus (GCRV)-induced gene 2h
chr3_-_55121125 0.17 ENSDART00000125092
hbae1
hemoglobin, alpha embryonic 1
chr23_+_2185397 0.17 ENSDART00000109373
c1qtnf7
C1q and TNF related 7
chr3_-_44012748 0.17 ENSDART00000167248
ENSDART00000157463
ENSDART00000159111
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr1_-_56717813 0.17 ENSDART00000159196
FO681314.1

chr6_+_39370587 0.17 ENSDART00000157165
ENSDART00000155079
si:dkey-195m11.8
si:dkey-195m11.8
chr4_+_57099307 0.16 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr9_-_17417628 0.16 ENSDART00000060425
ENSDART00000141997
ftr53
finTRIM family, member 53
chr17_+_16046314 0.16 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr19_+_10846182 0.16 ENSDART00000168479
apoa4a
apolipoprotein A-IV a
chr3_-_11008532 0.16 ENSDART00000165086
CR382337.3

chr9_-_27738110 0.16 ENSDART00000060347
crygs2
crystallin, gamma S2
chr18_+_44532199 0.16 ENSDART00000135386
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr2_+_45100963 0.16 ENSDART00000160122
CU929150.2

chr22_-_3344613 0.16 ENSDART00000165600
tbxa2r
thromboxane A2 receptor
chr7_+_26549846 0.16 ENSDART00000141353
tnk1
tyrosine kinase, non-receptor, 1
chr1_-_58664854 0.16 ENSDART00000109528
adgre5b.3
adhesion G protein-coupled receptor E5b, duplicate 3
chr1_-_11616295 0.15 ENSDART00000188891
si:dkey-26i13.5
si:dkey-26i13.5
chr20_-_25551676 0.15 ENSDART00000063081
cyp2ad3
cytochrome P450, family 2, subfamily AD, polypeptide 3
chr20_-_37813863 0.15 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr24_-_33291784 0.15 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr6_-_34220641 0.15 ENSDART00000102391
dmrt2b
doublesex and mab-3 related transcription factor 2b
chr16_-_26296477 0.15 ENSDART00000157553
erfl1
Ets2 repressor factor like 1
chr7_+_26167420 0.15 ENSDART00000173941
si:ch211-196f2.6
si:ch211-196f2.6
chr19_+_47783137 0.15 ENSDART00000024777
ENSDART00000158979
c19h1orf109
c19h1orf109 homolog (H. sapiens)
chr23_+_42292748 0.15 ENSDART00000166113
ENSDART00000158684
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr18_+_44532370 0.15 ENSDART00000086952
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr18_-_20444296 0.15 ENSDART00000132993
kif23
kinesin family member 23
chr18_+_10689772 0.15 ENSDART00000126441
lepa
leptin a
chr12_-_28983584 0.15 ENSDART00000112374
zgc:171713
zgc:171713
chr19_-_8798178 0.15 ENSDART00000188232
cers2a
ceramide synthase 2a
chr25_-_28587896 0.15 ENSDART00000111908
si:dkeyp-67e1.6
si:dkeyp-67e1.6
chr5_-_23118290 0.15 ENSDART00000132857
uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr18_+_13315739 0.14 ENSDART00000143404
si:ch211-260p9.3
si:ch211-260p9.3
chr21_-_17956416 0.14 ENSDART00000026737
stx2a
syntaxin 2a
chr3_-_50998577 0.14 ENSDART00000157735
cdc42ep4a
CDC42 effector protein (Rho GTPase binding) 4a
chr2_+_111919 0.14 ENSDART00000149391
fggy
FGGY carbohydrate kinase domain containing
chr22_+_24770744 0.14 ENSDART00000142882
si:rp71-23d18.4
si:rp71-23d18.4
chr23_+_1033668 0.14 ENSDART00000143391
si:zfos-905g2.1
si:zfos-905g2.1
chr11_-_11791718 0.14 ENSDART00000180476
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr14_-_24397718 0.14 ENSDART00000110164
si:ch211-163m17.4
si:ch211-163m17.4
chr14_-_22118055 0.14 ENSDART00000179892
si:dkey-6i22.5
si:dkey-6i22.5
chr13_-_8888334 0.14 ENSDART00000059881
plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr4_+_6639292 0.14 ENSDART00000158573
SMIM30
si:dkey-112e7.2
chr8_+_23711842 0.14 ENSDART00000128783
ppardb
peroxisome proliferator-activated receptor delta b
chr14_+_29945070 0.14 ENSDART00000185039
fam149a
family with sequence similarity 149 member A
chr18_-_46183462 0.14 ENSDART00000021192
kcnk6
potassium channel, subfamily K, member 6
chr7_+_25053331 0.14 ENSDART00000173998
si:dkey-23i12.7
si:dkey-23i12.7
chr3_+_25154078 0.14 ENSDART00000156973
si:ch211-256m1.8
si:ch211-256m1.8
chr13_-_37122217 0.14 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr6_-_7061086 0.14 ENSDART00000122719
ihhb
Indian hedgehog homolog b
chr6_+_28294113 0.14 ENSDART00000136898
lpp
LIM domain containing preferred translocation partner in lipoma
chr17_-_48743076 0.14 ENSDART00000173117
kcnk17
potassium channel, subfamily K, member 17
chr5_+_50953240 0.14 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr14_+_26229056 0.13 ENSDART00000179045
LO018208.1

chr8_-_23240156 0.13 ENSDART00000131632
ptk6a
PTK6 protein tyrosine kinase 6a
chr2_+_44972720 0.13 ENSDART00000075146
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr22_-_12745589 0.13 ENSDART00000136841
plcd4a
phospholipase C, delta 4a
chr12_-_26558038 0.13 ENSDART00000039510
tap2t
transporter associated with antigen processing, subunit type t, teleost specific
chr20_+_21595244 0.13 ENSDART00000010643
esr2a
estrogen receptor 2a
chr10_-_29827000 0.13 ENSDART00000131418
zpr1
ZPR1 zinc finger
chr25_-_1348370 0.13 ENSDART00000154865
itga11b
integrin, alpha 11b
chr13_-_2112008 0.13 ENSDART00000110814
fam83b
family with sequence similarity 83, member B
chr12_+_38983989 0.13 ENSDART00000156673
si:ch73-181m17.1
si:ch73-181m17.1
chr5_+_4366431 0.13 ENSDART00000168560
ENSDART00000149185
sat1a.2
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr23_+_42482137 0.13 ENSDART00000160199
cyp2aa3
cytochrome P450, family 2, subfamily AA, polypeptide 3
chr17_-_28811747 0.13 ENSDART00000001444
g2e3
G2/M-phase specific E3 ubiquitin protein ligase
chr19_-_7240627 0.13 ENSDART00000181874
FP101875.2

chr15_+_22333778 0.13 ENSDART00000114937
pde9al
phosphodiesterase 9A like
chr9_+_40825065 0.13 ENSDART00000137673
si:dkey-95p16.2
si:dkey-95p16.2
chr14_-_11507211 0.13 ENSDART00000186873
ENSDART00000109181
ENSDART00000186166
ENSDART00000186986
zgc:174917
zgc:174917
chr9_+_27348809 0.13 ENSDART00000147540
tlr20.1
toll-like receptor 20, tandem duplicate 1
chr1_+_58400409 0.13 ENSDART00000111526
si:ch73-59p9.2
si:ch73-59p9.2
chr18_+_45666489 0.12 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr16_-_1503023 0.12 ENSDART00000036348
sim1a
single-minded family bHLH transcription factor 1a
chr14_+_6182346 0.12 ENSDART00000075525
si:ch73-22a13.3
si:ch73-22a13.3
chr12_-_7157527 0.12 ENSDART00000152274
si:dkey-187i8.2
si:dkey-187i8.2
chr1_-_57839070 0.12 ENSDART00000152571
si:dkey-1c7.3
si:dkey-1c7.3
chr18_+_22109379 0.12 ENSDART00000147230
zgc:158868
zgc:158868
chr7_+_61876641 0.12 ENSDART00000165409
CR382383.2

chr1_+_55600504 0.12 ENSDART00000123946
umod
uromodulin
chr22_+_3238474 0.12 ENSDART00000157954
si:ch1073-178p5.3
si:ch1073-178p5.3
chr16_-_22729491 0.12 ENSDART00000189854
tlr19
toll-like receptor 19
chr25_+_36338289 0.12 ENSDART00000187881
zgc:165555
zgc:165555
chr25_-_21822426 0.12 ENSDART00000151993
zgc:158222
zgc:158222
chr10_+_23441488 0.12 ENSDART00000100783
si:ch73-122g19.1
si:ch73-122g19.1
chr15_-_5245726 0.12 ENSDART00000174079
ENSDART00000174041
or128-1
odorant receptor, family E, subfamily 128, member 1
chr3_+_50069610 0.12 ENSDART00000056619
zgc:103625
zgc:103625
chr9_-_12401871 0.12 ENSDART00000191901
nup35
nucleoporin 35
chr9_+_27354653 0.12 ENSDART00000134134
tlr20.2
toll-like receptor 20, tandem duplicate 2
chr13_-_31349284 0.12 ENSDART00000145887
rrp12
ribosomal RNA processing 12 homolog
chr22_+_6892296 0.12 ENSDART00000136968
FO904898.5

Network of associatons between targets according to the STRING database.

First level regulatory network of bcl6aa+bcl6ab+bcl6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 0.6 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.2 0.6 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 0.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.6 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.3 GO:0015677 copper ion import(GO:0015677)
0.1 0.2 GO:0072020 proximal straight tubule development(GO:0072020)
0.1 0.4 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.1 0.2 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.2 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.2 GO:0010039 response to iron ion(GO:0010039)
0.1 0.2 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 0.1 GO:0002370 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.1 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.2 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.4 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.1 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0055026 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 1.7 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.3 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.8 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.4 GO:2000344 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.1 GO:0016122 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.0 0.2 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.5 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.1 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.2 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.0 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0007340 acrosome reaction(GO:0007340)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.4 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.4 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 0.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.6 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 1.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.0 0.1 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0047192 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK