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PRJNA207719: Tissue specific transcriptome profiling

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Results for bhlhe40

Z-value: 0.44

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Transcription factors associated with bhlhe40

Gene Symbol Gene ID Gene Info
bhlhe40
ENSDARG00000004060 basic helix-loop-helix family, member e40

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bhlhe40dr11_v1_chr11_-_35763323_357633230.365.5e-01Click!

Activity profile of bhlhe40 motif

Sorted Z-values of bhlhe40 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_5268054 0.22 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr7_-_67214972 0.21 ENSDART00000156861
swap70a
switching B cell complex subunit SWAP70a
chr24_+_7631797 0.19 ENSDART00000187464
cavin1b
caveolae associated protein 1b
chr9_+_6587364 0.19 ENSDART00000122279
fhl2a
four and a half LIM domains 2a
chr5_-_4532516 0.16 ENSDART00000192398
cst14b.1
cystatin 14b, tandem duplicate 1
chr10_-_15644904 0.14 ENSDART00000138389
ENSDART00000101191
ENSDART00000186559
ENSDART00000122170
smc5
structural maintenance of chromosomes 5
chr13_+_7164345 0.12 ENSDART00000022051
gins1
GINS complex subunit 1 (Psf1 homolog)
chr21_-_5393125 0.12 ENSDART00000146061
psmd5
proteasome 26S subunit, non-ATPase 5
chr15_-_28596507 0.12 ENSDART00000156800
si:ch211-225b7.5
si:ch211-225b7.5
chr17_+_25331576 0.11 ENSDART00000157309
tmem54a
transmembrane protein 54a
chr5_-_66798729 0.11 ENSDART00000113077
FERMT3 (1 of many)
im:7154036
chr10_+_5422575 0.11 ENSDART00000063093
auh
AU RNA binding protein/enoyl-CoA hydratase
chr16_+_26824691 0.11 ENSDART00000135053
zmp:0000001316
zmp:0000001316
chr24_-_16917086 0.11 ENSDART00000110715
cmbl
carboxymethylenebutenolidase homolog (Pseudomonas)
chr8_+_41229233 0.11 ENSDART00000131135
zgc:152830
zgc:152830
chr15_-_1534232 0.11 ENSDART00000056763
ENSDART00000133943
ift80
intraflagellar transport 80 homolog (Chlamydomonas)
chr7_+_22293894 0.10 ENSDART00000056790
tmem256
transmembrane protein 256
chr25_+_10547228 0.10 ENSDART00000067678
zgc:110339
zgc:110339
chr8_-_25817106 0.10 ENSDART00000099364
taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr11_-_44945636 0.10 ENSDART00000157658
orc2
origin recognition complex, subunit 2
chr6_+_149405 0.10 ENSDART00000161154
fdx1l
ferredoxin 1-like
chr15_+_59417 0.10 ENSDART00000187260
AXL
AXL receptor tyrosine kinase
chr20_+_46213553 0.10 ENSDART00000100532
stx7l
syntaxin 7-like
chr9_+_36946340 0.10 ENSDART00000135281
si:dkey-3d4.3
si:dkey-3d4.3
chr16_-_7228276 0.09 ENSDART00000149030
nt5c3a
5'-nucleotidase, cytosolic IIIA
chr16_+_33143503 0.09 ENSDART00000058471
ENSDART00000179385
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr9_-_27868267 0.09 ENSDART00000079502
dbr1
debranching RNA lariats 1
chr14_-_36437249 0.09 ENSDART00000016728
aga
aspartylglucosaminidase
chr23_+_35847200 0.09 ENSDART00000129222
rarga
retinoic acid receptor gamma a
chr12_+_18529228 0.08 ENSDART00000193931
ENSDART00000146260
meiob
msrb1b
meiosis specific with OB domains
methionine sulfoxide reductase B1b
chr16_+_20895904 0.08 ENSDART00000052662
hoxa13b
homeobox A13b
chr19_-_27334394 0.08 ENSDART00000052359
gtf2h4
general transcription factor IIH, polypeptide 4
chr5_+_26204561 0.07 ENSDART00000137178
marveld2b
MARVEL domain containing 2b
chr9_-_10805231 0.07 ENSDART00000193913
ENSDART00000078348
si:ch1073-416j23.1
si:ch1073-416j23.1
chr11_+_42556395 0.06 ENSDART00000039206
rps23
ribosomal protein S23
chr2_-_32486080 0.06 ENSDART00000110821
ttc19
tetratricopeptide repeat domain 19
chr8_+_23738122 0.06 ENSDART00000062983
rpl10a
ribosomal protein L10a
chr19_+_791538 0.06 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr7_-_14446512 0.06 ENSDART00000041577
kif7
kinesin family member 7
chr22_+_16759010 0.06 ENSDART00000079638
ENSDART00000113099
tm2d1
TM2 domain containing 1
chr23_+_26079467 0.06 ENSDART00000129617
atp6ap1b
ATPase H+ transporting accessory protein 1b
chr4_-_9196291 0.05 ENSDART00000153963
hcfc2
host cell factor C2
chr22_+_30184039 0.05 ENSDART00000049075
add3a
adducin 3 (gamma) a
chr15_-_41807371 0.05 ENSDART00000156819
slc25a36b
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36b
chr7_-_41881177 0.05 ENSDART00000174258
ENSDART00000018972
zgc:92818
zgc:92818
chr16_+_5251768 0.05 ENSDART00000144558
plecb
plectin b
chr21_-_14251306 0.05 ENSDART00000114715
ENSDART00000181380
man1b1a
mannosidase, alpha, class 1B, member 1a
chr13_-_12389748 0.05 ENSDART00000141606
commd8
COMM domain containing 8
chr20_-_51100669 0.05 ENSDART00000023488
atp6v1d
ATPase H+ transporting V1 subunit D
chr1_+_54766943 0.05 ENSDART00000144759
nlrc6
NLR family CARD domain containing 6
chr5_+_57210237 0.05 ENSDART00000167660
pja2
praja ring finger ubiquitin ligase 2
chr9_-_38368138 0.05 ENSDART00000059574
ccdc93
coiled-coil domain containing 93
chr3_+_16922226 0.04 ENSDART00000017646
atp6v0a1a
ATPase H+ transporting V0 subunit a1a
chr19_-_5103313 0.04 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr12_+_17933775 0.04 ENSDART00000186047
ENSDART00000160586
trrap
transformation/transcription domain-associated protein
chr11_-_236984 0.04 ENSDART00000170778
dusp7
dual specificity phosphatase 7
chr17_-_2126517 0.04 ENSDART00000013093
zfyve19
zinc finger, FYVE domain containing 19
chr19_-_22346582 0.04 ENSDART00000045675
ENSDART00000169065
slc52a2
zgc:109744
solute carrier family 52 (riboflavin transporter), member 2
zgc:109744
chr25_+_3788074 0.04 ENSDART00000154008
chid1
chitinase domain containing 1
chr13_+_40692804 0.04 ENSDART00000109822
hps1
Hermansky-Pudlak syndrome 1
chr21_+_11916788 0.04 ENSDART00000136103
ubap2a
ubiquitin associated protein 2a
chr25_-_6223567 0.04 ENSDART00000067512
psma4
proteasome subunit alpha 4
chr23_-_31913231 0.03 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr19_+_15440841 0.03 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr18_+_31280984 0.03 ENSDART00000170285
ENSDART00000150608
ENSDART00000159720
def8
differentially expressed in FDCP 8 homolog (mouse)
chr20_-_29683754 0.03 ENSDART00000130599
ENSDART00000015928
ENSDART00000131219
si:ch211-195d17.2
si:ch211-195d17.2
chr17_+_30843881 0.03 ENSDART00000149600
ENSDART00000148547
tpp1
tripeptidyl peptidase I
chr20_-_51386511 0.03 ENSDART00000151429
ENSDART00000066072
rnf8
ring finger protein 8, E3 ubiquitin protein ligase
chr23_-_2901167 0.03 ENSDART00000165955
ENSDART00000190616
zhx3
zinc fingers and homeoboxes 3
chr4_+_17353714 0.03 ENSDART00000136299
nup37
nucleoporin 37
chr17_-_14705039 0.03 ENSDART00000154281
ENSDART00000123550
ptp4a2a
protein tyrosine phosphatase type IVA, member 2a
chr25_+_3788443 0.03 ENSDART00000189747
chid1
chitinase domain containing 1
chr14_+_94946 0.03 ENSDART00000165766
ENSDART00000163778
mcm7
minichromosome maintenance complex component 7
chr23_+_9035578 0.03 ENSDART00000140455
ccm2l
cerebral cavernous malformation 2-like
chr12_+_34891529 0.02 ENSDART00000015643
tbcc
tubulin folding cofactor C
chr5_-_22130937 0.02 ENSDART00000138606
las1l
LAS1-like, ribosome biogenesis factor
chr24_-_21498802 0.02 ENSDART00000181235
ENSDART00000153695
atp8a2
ATPase phospholipid transporting 8A2
chr19_+_15441022 0.02 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr8_-_41228530 0.02 ENSDART00000165949
ENSDART00000173055
fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chr12_+_19958845 0.02 ENSDART00000193248
ercc4
excision repair cross-complementation group 4
chr15_+_6652396 0.02 ENSDART00000192813
ENSDART00000157678
nop53
NOP53 ribosome biogenesis factor
chr24_-_6024466 0.02 ENSDART00000040865
pdss1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr24_-_35534273 0.02 ENSDART00000026578
ube2v2
ubiquitin-conjugating enzyme E2 variant 2
chr12_-_43438148 0.02 ENSDART00000004122
ptprea
protein tyrosine phosphatase, receptor type, E, a
chr5_+_61839707 0.02 ENSDART00000163051
CR759879.1
Danio rerio interferon-induced protein with tetratricopeptide repeats 5 (LOC572297), mRNA.
chr18_+_39074139 0.02 ENSDART00000142390
gnb5b
guanine nucleotide binding protein (G protein), beta 5b
chr24_-_42072886 0.02 ENSDART00000171389
CABZ01095370.1

chr6_+_12968101 0.02 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr5_+_32835219 0.02 ENSDART00000140832
ENSDART00000186055
si:ch211-208h16.4
si:ch211-208h16.4
chr23_+_31913292 0.02 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr10_+_32050906 0.02 ENSDART00000137373
si:ch211-266i6.3
si:ch211-266i6.3
chr16_+_7985886 0.02 ENSDART00000126041
ano10a
anoctamin 10a
chr4_+_17655872 0.01 ENSDART00000066999
washc3
WASH complex subunit 3
chr16_+_19029297 0.01 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr23_+_32028574 0.01 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr16_+_25296389 0.01 ENSDART00000114528
tbc1d31
TBC1 domain family, member 31
chr17_+_32622933 0.01 ENSDART00000077418
ctsba
cathepsin Ba
chr13_+_12389849 0.01 ENSDART00000086525
atp10d
ATPase phospholipid transporting 10D
chr6_+_7123980 0.01 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
si:ch211-237c6.4
chr17_-_37299394 0.01 ENSDART00000154414
ptgr2
prostaglandin reductase 2
chr19_+_9111550 0.01 ENSDART00000088336
setdb1a
SET domain, bifurcated 1a
chr20_-_45040916 0.01 ENSDART00000190001
klhl29
kelch-like family member 29
chr23_+_42131509 0.01 ENSDART00000184544
SHISAL2A
shisa like 2A
chr10_-_24724388 0.00 ENSDART00000148582
smpd1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr5_+_41476443 0.00 ENSDART00000145228
ENSDART00000137981
ENSDART00000142538
pias2
protein inhibitor of activated STAT, 2
chr1_-_54765262 0.00 ENSDART00000150362
si:ch211-197k17.3
si:ch211-197k17.3
chr23_-_22130778 0.00 ENSDART00000079212
phc2a
polyhomeotic homolog 2a (Drosophila)
chr12_-_7280551 0.00 ENSDART00000061633
zgc:171971
zgc:171971
chr24_+_12989727 0.00 ENSDART00000126842
ENSDART00000129309
flj11011l
hypothetical protein FLJ11011-like (H. sapiens)
chr23_-_10786400 0.00 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr20_-_40766387 0.00 ENSDART00000061173
hsdl1
hydroxysteroid dehydrogenase like 1
chr15_-_26570948 0.00 ENSDART00000156621
wdr81
WD repeat domain 81
chr2_+_50967947 0.00 ENSDART00000162288
si:ch211-249o11.5
si:ch211-249o11.5
chr3_-_25420931 0.00 ENSDART00000109601
ENSDART00000182184
bptf
bromodomain PHD finger transcription factor
chr15_+_1148074 0.00 ENSDART00000152638
ENSDART00000152466
ENSDART00000188011
mlf1
myeloid leukemia factor 1
chr17_-_25331439 0.00 ENSDART00000155422
ENSDART00000082324
zpcx
zona pellucida protein C

Network of associatons between targets according to the STRING database.

First level regulatory network of bhlhe40

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.0 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.0 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA