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PRJNA207719: Tissue specific transcriptome profiling

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Results for cdc5l

Z-value: 1.94

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Transcription factors associated with cdc5l

Gene Symbol Gene ID Gene Info
cdc5l
ENSDARG00000043797 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cdc5ldr11_v1_chr17_+_5061135_5061135-0.001.0e+00Click!

Activity profile of cdc5l motif

Sorted Z-values of cdc5l motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_33606739 2.05 ENSDART00000026464
cfl1l
cofilin 1 (non-muscle), like
chr19_-_31372896 2.04 ENSDART00000046609
scin
scinderin
chr16_-_25085327 1.99 ENSDART00000077661
prss1
protease, serine 1
chr1_-_45177373 1.37 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr18_+_7591381 1.34 ENSDART00000136313
si:dkeyp-1h4.6
si:dkeyp-1h4.6
chr6_-_49063085 1.26 ENSDART00000156124
si:ch211-105j21.9
si:ch211-105j21.9
chr22_+_7439186 1.23 ENSDART00000190667
zgc:92041
zgc:92041
chr10_+_2669405 1.19 ENSDART00000110202
ccl27b
chemokine (C-C motif) ligand 27b
chr8_-_29719393 1.16 ENSDART00000077635
si:ch211-103n10.5
si:ch211-103n10.5
chr12_+_46512881 1.12 ENSDART00000105454
CU855711.1

chr12_+_5708400 1.10 ENSDART00000017191
dlx3b
distal-less homeobox 3b
chr15_-_12360409 1.03 ENSDART00000164596
tmprss13a
transmembrane protease, serine 13a
chr23_+_5631381 1.03 ENSDART00000149143
pkp1a
plakophilin 1a
chr16_-_45230084 1.00 ENSDART00000184652
si:dkey-33i11.4
si:dkey-33i11.4
chr1_-_52447364 0.95 ENSDART00000140740
si:ch211-217k17.10
si:ch211-217k17.10
chr17_-_32426392 0.92 ENSDART00000148455
ENSDART00000149885
ENSDART00000179314
grhl1
grainyhead-like transcription factor 1
chr21_+_20771082 0.89 ENSDART00000079732
oxct1b
3-oxoacid CoA transferase 1b
chr1_-_10647307 0.89 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr22_-_10580194 0.89 ENSDART00000105848
SHISA4 (1 of many)
si:dkey-42i9.7
chr23_-_44903048 0.88 ENSDART00000149103
fhdc5
FH2 domain containing 5
chr3_-_61162750 0.88 ENSDART00000055064
pvalb8
parvalbumin 8
chr24_-_31904924 0.88 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
si:ch73-78o10.1
chr4_-_11580948 0.86 ENSDART00000049066
net1
neuroepithelial cell transforming 1
chr19_-_3244360 0.84 ENSDART00000142222
zgc:158445
zgc:158445
chr24_-_38131381 0.83 ENSDART00000105666
crp6
C-reactive protein 6
chr17_+_5985933 0.83 ENSDART00000190844
zgc:194275
zgc:194275
chr7_+_24881680 0.83 ENSDART00000058843
krcp
kelch repeat-containing protein
chr5_-_55560937 0.82 ENSDART00000148436
gna14
guanine nucleotide binding protein (G protein), alpha 14
chr19_+_2835240 0.81 ENSDART00000190838
CDCP1
CUB domain containing protein 1
chr3_-_32957702 0.79 ENSDART00000146586
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr24_+_27511734 0.79 ENSDART00000105771
cxcl32b.1
chemokine (C-X-C motif) ligand 32b, duplicate 1
chr9_+_52398531 0.78 ENSDART00000126215
dap1b
death associated protein 1b
chr12_-_30549022 0.76 ENSDART00000102474
zgc:158404
zgc:158404
chr16_-_12060770 0.76 ENSDART00000183237
ENSDART00000103948
si:ch211-69g19.2
si:ch211-69g19.2
chr16_+_55059026 0.75 ENSDART00000109391
LO017815.1
Danio rerio nuclear receptor coactivator 7-like (LOC792958), mRNA.
chr2_-_19234329 0.73 ENSDART00000161106
ENSDART00000160060
ENSDART00000174552
cdc20
cell division cycle 20 homolog
chr12_+_46462090 0.73 ENSDART00000130748
BX005305.2

chr13_-_37620091 0.72 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
zgc:152791
chr1_-_38171648 0.69 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr4_-_17812131 0.69 ENSDART00000025731
spic
Spi-C transcription factor (Spi-1/PU.1 related)
chr1_-_10647484 0.68 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr16_+_29509133 0.67 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr16_+_23947196 0.67 ENSDART00000103190
ENSDART00000132961
ENSDART00000147690
ENSDART00000142168
apoa4b.2
apolipoprotein A-IV b, tandem duplicate 2
chr2_-_8648440 0.66 ENSDART00000135743
si:ch211-71m22.3
si:ch211-71m22.3
chr25_+_25202213 0.66 ENSDART00000150744
ccl39a.10
chemokine (C-C motif) ligand 39, duplicate 10
chr2_+_40181633 0.66 ENSDART00000185494
FP236331.1

chr16_-_26140768 0.65 ENSDART00000143960
cd79a
CD79a molecule, immunoglobulin-associated alpha
chr4_+_1461079 0.64 ENSDART00000082383
trim35-14
tripartite motif containing 35-14
chr2_+_10134345 0.63 ENSDART00000100725
ahsg2
alpha-2-HS-glycoprotein 2
chr17_-_36529449 0.62 ENSDART00000187252
colec11
collectin sub-family member 11
chr23_+_28381260 0.62 ENSDART00000162722
zgc:153867
zgc:153867
chr9_-_9415000 0.62 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr6_-_609880 0.62 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lgals2b
lectin, galactoside-binding, soluble, 2b
chr6_+_56141852 0.61 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr15_+_28410664 0.61 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
pitpnaa
phosphatidylinositol transfer protein, alpha a
chr15_-_47929455 0.61 ENSDART00000064462
psma6l
proteasome subunit alpha 6, like
chr15_-_34892664 0.60 ENSDART00000153787
ENSDART00000099721
rnf183
ring finger protein 183
chr16_+_35916371 0.60 ENSDART00000167208
sh3d21
SH3 domain containing 21
chr8_+_47099033 0.60 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr3_+_62161184 0.60 ENSDART00000090370
ENSDART00000192665
noxo1a
NADPH oxidase organizer 1a
chr21_+_28749720 0.59 ENSDART00000145178
zgc:100829
zgc:100829
chr3_-_7990516 0.59 ENSDART00000167877
TRIM35 (1 of many)
si:ch211-175l6.2
chr16_-_12060488 0.59 ENSDART00000188733
si:ch211-69g19.2
si:ch211-69g19.2
chr15_+_28096152 0.58 ENSDART00000100293
ENSDART00000140092
crybb1l3
crystallin, beta B1, like 3
chr25_-_22191983 0.58 ENSDART00000191181
pkp3a
plakophilin 3a
chr8_+_39674707 0.57 ENSDART00000126301
ENSDART00000040330
prkab1b
protein kinase, AMP-activated, beta 1 non-catalytic subunit, b
chr22_+_1911269 0.57 ENSDART00000164158
ENSDART00000168205
znf1156
zinc finger protein 1156
chr1_-_18848955 0.57 ENSDART00000109294
ENSDART00000146410
zgc:195282
zgc:195282
chr24_+_12945803 0.56 ENSDART00000005105
psme1
proteasome activator subunit 1
chr18_-_46354269 0.56 ENSDART00000010813
foxa3
forkhead box A3
chr15_+_934660 0.55 ENSDART00000154248
si:dkey-77f5.10
si:dkey-77f5.10
chr23_+_32011768 0.55 ENSDART00000053509
plagx
pleiomorphic adenoma gene X
chr1_+_9966384 0.55 ENSDART00000132607
si:dkeyp-75b4.8
si:dkeyp-75b4.8
chr3_-_26921475 0.54 ENSDART00000130281
ciita
class II, major histocompatibility complex, transactivator
chr6_-_436658 0.53 ENSDART00000191515
grap2b
GRB2-related adaptor protein 2b
chr21_-_17296010 0.53 ENSDART00000114877
gfi1b
growth factor independent 1B transcription repressor
chr5_+_45918680 0.53 ENSDART00000036242
ankdd1b
ankyrin repeat and death domain containing 1B
chr5_-_62317496 0.52 ENSDART00000180089
zgc:85789
zgc:85789
chr18_+_13203831 0.52 ENSDART00000032151
cotl1
coactosin-like F-actin binding protein 1
chr21_-_5205617 0.52 ENSDART00000145554
ENSDART00000045284
rpl37
ribosomal protein L37
chr11_-_10659195 0.52 ENSDART00000115255
mcf2l2
MCF.2 cell line derived transforming sequence-like 2
chr6_+_40992409 0.52 ENSDART00000151419
tgfa
transforming growth factor, alpha
chr16_-_32208728 0.52 ENSDART00000023995
calhm5.2
calcium homeostasis modulator family member 5, tandem duplicate 2
chr15_-_41689981 0.52 ENSDART00000059327
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr5_-_61652254 0.52 ENSDART00000097364
drl
draculin
chr13_-_45155792 0.52 ENSDART00000163556
runx3
runt-related transcription factor 3
chr7_-_8315179 0.51 ENSDART00000184049
f13a1b
coagulation factor XIII, A1 polypeptide b
chr3_-_24681404 0.51 ENSDART00000161612
BX569789.1

chr18_+_36631923 0.51 ENSDART00000098980
znf296
zinc finger protein 296
chr16_-_11859309 0.51 ENSDART00000145754
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr14_+_15622817 0.51 ENSDART00000158624
si:dkey-203a12.9
si:dkey-203a12.9
chr2_+_50967947 0.51 ENSDART00000162288
si:ch211-249o11.5
si:ch211-249o11.5
chr3_-_54846444 0.51 ENSDART00000074010
ubald1b
UBA-like domain containing 1b
chr10_+_8656417 0.50 ENSDART00000123131
pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr1_-_43915423 0.50 ENSDART00000181915
ENSDART00000113673
scpp5
secretory calcium-binding phosphoprotein 5
chr19_-_13933204 0.49 ENSDART00000158059
trnau1apa
tRNA selenocysteine 1 associated protein 1a
chr8_-_16725573 0.49 ENSDART00000049676
depdc1a
DEP domain containing 1a
chr9_+_44994214 0.48 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr17_+_6563307 0.48 ENSDART00000156454
adgrf3a
adhesion G protein-coupled receptor F3a
chr18_-_29925717 0.47 ENSDART00000099281
mhc2dbb
major histocompatibility complex class II DBB gene
chr11_+_37201483 0.47 ENSDART00000160930
ENSDART00000173439
ENSDART00000171273
zgc:112265
zgc:112265
chr21_-_28439596 0.47 ENSDART00000089980
ENSDART00000132844
rasgrp2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr5_+_21181047 0.47 ENSDART00000088506
arhgap25
Rho GTPase activating protein 25
chr17_-_36529016 0.47 ENSDART00000025019
colec11
collectin sub-family member 11
chr13_-_42757565 0.46 ENSDART00000161950
capn2a
calpain 2, (m/II) large subunit a
chr15_-_17813680 0.46 ENSDART00000158556
CT573342.2

chr24_-_3426620 0.46 ENSDART00000184346
nck1b
NCK adaptor protein 1b
chr3_-_11203689 0.46 ENSDART00000166328
BX323882.1

chr20_+_43691208 0.46 ENSDART00000152976
ENSDART00000045185
lin9
lin-9 DREAM MuvB core complex component
chr1_-_7570181 0.46 ENSDART00000103588
mxa
myxovirus (influenza) resistance A
chr16_+_23398369 0.46 ENSDART00000037694
s100a10b
S100 calcium binding protein A10b
chr25_+_5249513 0.46 ENSDART00000126814
CABZ01039863.1

chr20_+_23238833 0.46 ENSDART00000074167
ociad2
OCIA domain containing 2
chr19_-_27588842 0.45 ENSDART00000121643
si:dkeyp-46h3.2
si:dkeyp-46h3.2
chr7_-_16598212 0.45 ENSDART00000128488
e2f8
E2F transcription factor 8
chr5_-_37117778 0.45 ENSDART00000149138
il13ra2
interleukin 13 receptor, alpha 2
chr18_-_48296793 0.45 ENSDART00000032184
ENSDART00000193076
CABZ01069595.1

chr12_+_20641102 0.44 ENSDART00000152964
calcoco2
calcium binding and coiled-coil domain 2
chr21_+_11560153 0.44 ENSDART00000065842
cd8a
CD8a molecule
chr3_+_22375596 0.44 ENSDART00000188243
ENSDART00000181506
arhgap27l
Rho GTPase activating protein 27, like
chr22_-_22301672 0.44 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr4_-_38308760 0.43 ENSDART00000190780
si:ch211-229l10.4
si:ch211-229l10.4
chr8_-_14554785 0.43 ENSDART00000057645
qsox1
quiescin Q6 sulfhydryl oxidase 1
chr16_-_25741225 0.43 ENSDART00000130641
bcl3
B cell CLL/lymphoma 3
chr21_-_43457554 0.43 ENSDART00000085039
stk26
serine/threonine protein kinase 26
chr2_+_31671545 0.43 ENSDART00000145446
ackr4a
atypical chemokine receptor 4a
chr16_-_46567344 0.42 ENSDART00000127721
si:dkey-152b24.7
si:dkey-152b24.7
chr4_-_11064073 0.42 ENSDART00000150760
si:dkey-21h14.8
si:dkey-21h14.8
chr19_+_7636941 0.42 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr11_+_14284866 0.42 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr4_-_76370630 0.42 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr4_+_5205265 0.41 ENSDART00000067382
galnt8b.1
polypeptide N-acetylgalactosaminyltransferase 8b, tandem duplicate 1
chr22_+_30631072 0.41 ENSDART00000059970
zmp:0000000606
zmp:0000000606
chr25_-_3217115 0.41 ENSDART00000032390
gtf2h1
general transcription factor IIH, polypeptide 1
chr22_+_7742211 0.41 ENSDART00000140896
CELA1 (1 of many)
zgc:92511
chr10_-_35153388 0.41 ENSDART00000188132
ripk4
receptor-interacting serine-threonine kinase 4
chr5_-_61624693 0.40 ENSDART00000141323
si:dkey-261j4.4
si:dkey-261j4.4
chr20_+_53522059 0.40 ENSDART00000147570
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr19_+_7045033 0.40 ENSDART00000146579
mhc1uka
major histocompatibility complex class I UKA
chr20_+_51104367 0.40 ENSDART00000073981
eif2s1b
eukaryotic translation initiation factor 2, subunit 1 alpha b
chr21_+_15295685 0.40 ENSDART00000135603
BX901878.1

chr1_+_57187794 0.40 ENSDART00000152485
si:dkey-27j5.9
si:dkey-27j5.9
chr2_+_24507597 0.39 ENSDART00000133109
rps28
ribosomal protein S28
chr6_-_49526510 0.39 ENSDART00000128025
rps26l
ribosomal protein S26, like
chr21_-_31226045 0.39 ENSDART00000011572
zgc:152891
zgc:152891
chr2_+_45552901 0.39 ENSDART00000131701
fndc7a
fibronectin type III domain containing 7a
chr4_-_13614797 0.39 ENSDART00000138366
ENSDART00000165212
irf5
interferon regulatory factor 5
chr16_-_33104944 0.39 ENSDART00000151943
pnrc2
proline-rich nuclear receptor coactivator 2
chr1_-_51734524 0.39 ENSDART00000109640
ENSDART00000122628
junba
JunB proto-oncogene, AP-1 transcription factor subunit a
chr22_-_22301929 0.39 ENSDART00000142027
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr1_-_11104805 0.39 ENSDART00000147648
knl1
kinetochore scaffold 1
chr17_+_16090436 0.39 ENSDART00000136059
ENSDART00000138734
znf395a
zinc finger protein 395a
chr19_-_10551394 0.38 ENSDART00000186815
ENSDART00000181041
lim2.4
lens intrinsic membrane protein 2.4
chr15_-_29573267 0.38 ENSDART00000099947
samsn1a
SAM domain, SH3 domain and nuclear localisation signals 1a
chr14_+_9456675 0.38 ENSDART00000134935
rell2
RELT-like 2
chr1_-_53880639 0.38 ENSDART00000010543
ltv1
LTV1 ribosome biogenesis factor
chr9_+_38645136 0.38 ENSDART00000135505
slc12a8
solute carrier family 12, member 8
chr25_+_35051656 0.38 ENSDART00000133379
hist2h3c
histone cluster 2, H3c
chr2_-_10877228 0.37 ENSDART00000138718
ENSDART00000034246
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr2_-_5840494 0.37 ENSDART00000154877
si:ch211-273k1.5
si:ch211-273k1.5
chr7_-_20464468 0.37 ENSDART00000134700
cnpy4
canopy4
chr18_+_31073265 0.37 ENSDART00000023539
cyba
cytochrome b-245, alpha polypeptide
chr11_+_35050253 0.37 ENSDART00000124800
fam212aa
family with sequence similarity 212, member Aa
chr17_-_5424175 0.37 ENSDART00000171063
ENSDART00000188102
supt3h
SPT3 homolog, SAGA and STAGA complex component
chr10_+_10313024 0.37 ENSDART00000142895
ENSDART00000129952
urm1
ubiquitin related modifier 1
chr1_-_49505449 0.37 ENSDART00000187294
ENSDART00000132171
si:dkeyp-80c12.5
si:dkeyp-80c12.5
chr2_-_36604589 0.37 ENSDART00000167352
tradv41.0
T-cell receptor alpha/delta variable 41.0
chr17_-_15189397 0.36 ENSDART00000133710
ENSDART00000110507
wdhd1
WD repeat and HMG-box DNA binding protein 1
chr15_+_37986069 0.36 ENSDART00000156984
si:dkey-238d18.8
si:dkey-238d18.8
chr15_-_5815006 0.36 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr14_-_34633960 0.36 ENSDART00000128869
ENSDART00000179977
afap1l1a
actin filament associated protein 1-like 1a
chr17_-_31695217 0.36 ENSDART00000104332
ENSDART00000143090
lin52
lin-52 DREAM MuvB core complex component
chr25_-_3228025 0.36 ENSDART00000165924
cib1
calcium and integrin binding 1 (calmyrin)
chr20_+_19006703 0.36 ENSDART00000128435
pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr8_-_45756434 0.36 ENSDART00000179658
ppiaa
peptidylprolyl isomerase Aa (cyclophilin A)
chr1_-_58064738 0.36 ENSDART00000073778
caspb
caspase b
chr21_+_45816030 0.36 ENSDART00000187056
pitx1
paired-like homeodomain 1
chr1_-_55008882 0.35 ENSDART00000083572
zgc:136864
zgc:136864
chr25_-_15040369 0.35 ENSDART00000159342
ENSDART00000166490
pax6a
paired box 6a
chr7_+_25053331 0.35 ENSDART00000173998
si:dkey-23i12.7
si:dkey-23i12.7
chr10_+_24627683 0.35 ENSDART00000112652
slc46a3
solute carrier family 46, member 3
chr6_+_60125033 0.35 ENSDART00000148557
ENSDART00000008224
aurka
aurora kinase A
chr20_-_26491567 0.35 ENSDART00000147154
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr10_+_13209580 0.35 ENSDART00000000887
ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr20_-_30377221 0.35 ENSDART00000126229
rps7
ribosomal protein S7
chr6_+_40992883 0.34 ENSDART00000076061
tgfa
transforming growth factor, alpha
chr15_-_41689684 0.34 ENSDART00000143447
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr10_-_21362320 0.34 ENSDART00000189789
avd
avidin
chr15_+_6652396 0.34 ENSDART00000192813
ENSDART00000157678
nop53
NOP53 ribosome biogenesis factor
chr8_-_13010011 0.34 ENSDART00000140969
dennd2da
DENN/MADD domain containing 2Da
chr3_-_16537441 0.34 ENSDART00000080749
ENSDART00000133824
eps8l1
eps8-like1
chr3_-_21382491 0.34 ENSDART00000016562
itga2b
integrin, alpha 2b
chr1_+_25178106 0.34 ENSDART00000054265
ENSDART00000141648
mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr8_-_20245892 0.34 ENSDART00000136911
acer1
alkaline ceramidase 1
chr1_-_12161148 0.33 ENSDART00000166429
b4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr8_-_46486009 0.33 ENSDART00000140431
sult1st9
sulfotransferase family 1, cytosolic sulfotransferase 9
chr2_-_30182353 0.33 ENSDART00000019149
rpl7
ribosomal protein L7
chr11_-_16152400 0.33 ENSDART00000123665
arpc4l
actin related protein 2/3 complex, subunit 4, like
chr6_+_23712911 0.33 ENSDART00000167795
zgc:158654
zgc:158654
chr2_-_47620806 0.33 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b

Network of associatons between targets according to the STRING database.

First level regulatory network of cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 1.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 0.6 GO:0048785 hatching gland development(GO:0048785)
0.2 0.9 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 0.9 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.5 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.3 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.5 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.1 0.3 GO:0030521 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.3 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.1 1.1 GO:0019730 antimicrobial humoral response(GO:0019730)
0.1 2.3 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.1 0.3 GO:0010039 response to iron ion(GO:0010039)
0.1 1.2 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.4 GO:0032447 protein urmylation(GO:0032447)
0.1 0.2 GO:0042148 strand invasion(GO:0042148)
0.1 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.2 GO:0045601 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.2 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.6 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.5 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.1 0.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.1 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.2 GO:0016109 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.6 GO:0030719 P granule organization(GO:0030719)
0.1 0.3 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.6 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.5 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.9 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.6 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 1.0 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.1 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.3 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0003210 cardiac atrium formation(GO:0003210)
0.0 0.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.3 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.5 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0051031 tRNA transport(GO:0051031)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.2 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.3 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.6 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.8 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.1 GO:0060912 cardiac cell fate specification(GO:0060912)
0.0 0.7 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.3 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.0 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.0 0.1 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.3 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.0 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.7 GO:0051058 negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.4 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.1 GO:0036473 cell death in response to oxidative stress(GO:0036473) negative regulation of cellular response to oxidative stress(GO:1900408) negative regulation of response to oxidative stress(GO:1902883) regulation of oxidative stress-induced cell death(GO:1903201) negative regulation of oxidative stress-induced cell death(GO:1903202)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 1.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.5 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.3 GO:0042744 oxygen transport(GO:0015671) hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 0.3 GO:0009749 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.7 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0017145 stem cell division(GO:0017145)
0.0 0.1 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.1 GO:0071632 optomotor response(GO:0071632)
0.0 0.6 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.3 GO:0007568 aging(GO:0007568)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.6 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0023058 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) G-protein coupled receptor internalization(GO:0002031) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.1 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.6 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.4 GO:0007548 sex differentiation(GO:0007548)
0.0 0.1 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.0 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.0 0.9 GO:0061136 regulation of proteasomal protein catabolic process(GO:0061136)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0019815 B cell receptor complex(GO:0019815)
0.2 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.8 GO:0033186 CAF-1 complex(GO:0033186)
0.2 2.4 GO:0002102 podosome(GO:0002102)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.4 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 0.3 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 0.4 GO:0061702 inflammasome complex(GO:0061702)
0.1 1.6 GO:0030057 desmosome(GO:0030057)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.3 GO:0032433 filopodium tip(GO:0032433)
0.1 0.4 GO:0030914 STAGA complex(GO:0030914)
0.1 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.1 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.6 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.0 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.0 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.0 1.6 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.0 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0042806 fucose binding(GO:0042806)
0.2 0.6 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.2 0.8 GO:0070513 death domain binding(GO:0070513)
0.2 0.9 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.7 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.4 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.3 GO:0019767 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.1 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.2 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.3 GO:0009374 biotin binding(GO:0009374)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.2 GO:0032356 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.4 GO:0048156 tau protein binding(GO:0048156)
0.1 1.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.2 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 2.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0030975 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.6 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0008144 drug binding(GO:0008144) cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.5 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres