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PRJNA207719: Tissue specific transcriptome profiling

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Results for cebpa

Z-value: 1.74

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Transcription factors associated with cebpa

Gene Symbol Gene ID Gene Info
cebpa
ENSDARG00000036074 CCAAT enhancer binding protein alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cebpadr11_v1_chr7_-_38087865_38087865-0.828.9e-02Click!

Activity profile of cebpa motif

Sorted Z-values of cebpa motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_50147948 2.65 ENSDART00000149010
hp
haptoglobin
chr1_+_59067978 1.67 ENSDART00000172613
MFAP4 (1 of many)
si:ch1073-110a20.7
chr5_-_63509581 1.65 ENSDART00000097325
c5
complement component 5
chr16_-_21785261 1.60 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr14_+_21107032 1.40 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr3_+_19299309 1.30 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr14_+_21106444 1.26 ENSDART00000075744
ENSDART00000132363
aldob
aldolase b, fructose-bisphosphate
chr9_+_38292947 1.23 ENSDART00000146663
tfcp2l1
transcription factor CP2-like 1
chr14_+_16345003 1.19 ENSDART00000003040
ENSDART00000165193
itln3
intelectin 3
chr22_-_26236188 1.17 ENSDART00000162640
ENSDART00000167169
ENSDART00000138595
c3b.1
complement component c3b, tandem duplicate 1
chr21_+_20901505 1.17 ENSDART00000132741
c7b
complement component 7b
chr8_-_13972626 1.16 ENSDART00000144296
serping1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr6_+_21202639 1.15 ENSDART00000083126
cidec
cell death-inducing DFFA-like effector c
chr20_+_23440632 1.15 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr8_-_39739627 1.10 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
si:ch211-170d8.5
chr19_-_5699703 1.09 ENSDART00000082050
zgc:174904
zgc:174904
chr19_+_5674907 1.08 ENSDART00000042189
pdk2b
pyruvate dehydrogenase kinase, isozyme 2b
chr9_-_32847642 1.07 ENSDART00000121506
hpx
hemopexin
chr1_+_24376394 1.05 ENSDART00000102542
zgc:171517
zgc:171517
chr22_-_26175237 1.01 ENSDART00000108737
c3b.2
complement component c3b, tandem duplicate 2
chr15_+_28202170 1.00 ENSDART00000077736
vtna
vitronectin a
chr13_-_20540790 0.97 ENSDART00000131467
si:ch1073-126c3.2
si:ch1073-126c3.2
chr16_+_50289916 0.97 ENSDART00000168861
ENSDART00000167332
hamp
hepcidin antimicrobial peptide
chr25_-_32311048 0.93 ENSDART00000181806
ENSDART00000086334
CU372926.1

chr11_+_37178271 0.92 ENSDART00000161771
itih3b
inter-alpha-trypsin inhibitor heavy chain 3b
chr2_-_51794472 0.92 ENSDART00000186652
BX908782.3

chr1_+_10051763 0.91 ENSDART00000011701
fgb
fibrinogen beta chain
chr1_-_10071422 0.90 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr5_+_44805269 0.89 ENSDART00000136965
ctsla
cathepsin La
chr7_+_56577522 0.87 ENSDART00000149130
ENSDART00000149624
hp
haptoglobin
chr14_+_36885524 0.86 ENSDART00000032547
lect2l
leukocyte cell-derived chemotaxin 2 like
chr16_+_23984179 0.86 ENSDART00000175879
apoc2
apolipoprotein C-II
chr19_-_15192840 0.86 ENSDART00000151337
phactr4a
phosphatase and actin regulator 4a
chr6_+_22068589 0.85 ENSDART00000151205
aldh1l1
aldehyde dehydrogenase 1 family, member L1
chr22_-_36875264 0.84 ENSDART00000137548
kng1
kininogen 1
chr19_+_8606883 0.81 ENSDART00000054469
ENSDART00000185264
s100a10a
S100 calcium binding protein A10a
chr24_-_38094074 0.81 ENSDART00000140802
ENSDART00000137734
crp2
C-reactive protein 2
chr5_+_45677781 0.81 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr15_+_14856307 0.78 ENSDART00000167213
diabloa
diablo, IAP-binding mitochondrial protein a
chr7_-_60831082 0.77 ENSDART00000073654
ENSDART00000136999
pcxb
pyruvate carboxylase b
chr5_+_28830388 0.77 ENSDART00000149150
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr13_-_24257631 0.77 ENSDART00000146524
urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr17_-_36529449 0.75 ENSDART00000187252
colec11
collectin sub-family member 11
chr14_+_15155684 0.74 ENSDART00000167966
zgc:158852
zgc:158852
chr25_+_31323978 0.73 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr23_+_17980875 0.70 ENSDART00000163452
chia.6
chitinase, acidic.6
chr2_-_32643738 0.69 ENSDART00000112452
si:dkeyp-73d8.9
si:dkeyp-73d8.9
chr23_+_45282858 0.67 ENSDART00000162353
CABZ01073265.1

chr3_-_10749691 0.67 ENSDART00000183088
CU210890.1

chr3_-_36750068 0.66 ENSDART00000173388
abcc6b.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr17_-_6519423 0.65 ENSDART00000175626
CR628323.3

chr15_-_29348212 0.64 ENSDART00000133117
tsku
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr5_+_9360394 0.62 ENSDART00000124642
FP236810.2

chr8_-_26961779 0.62 ENSDART00000099214
slc16a1b
solute carrier family 16 (monocarboxylate transporter), member 1b
chr2_-_127945 0.62 ENSDART00000056453
igfbp1b
insulin-like growth factor binding protein 1b
chr22_-_20695237 0.61 ENSDART00000112722
org
oogenesis-related gene
chr10_-_23099809 0.61 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
nle1
notchless homolog 1 (Drosophila)
chr5_+_44805028 0.61 ENSDART00000141198
ctsla
cathepsin La
chr17_+_30450163 0.61 ENSDART00000104257
lpin1
lipin 1
chr9_-_9989660 0.60 ENSDART00000081463
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr1_-_56032619 0.60 ENSDART00000143793
c3a.4
complement component c3a, duplicate 4
chr5_-_25723079 0.60 ENSDART00000014013
gda
guanine deaminase
chr20_-_52271262 0.58 ENSDART00000135463
rhpn1
rhophilin, Rho GTPase binding protein 1
chr7_-_4296771 0.57 ENSDART00000128855
cbln11
cerebellin 11
chr3_-_3439150 0.56 ENSDART00000021286
A2ML1 (1 of many)
si:dkey-46g23.5
chr5_+_26795773 0.56 ENSDART00000145631
tcn2
transcobalamin II
chr7_-_66864756 0.55 ENSDART00000184462
ENSDART00000189424
ampd3a
adenosine monophosphate deaminase 3a
chr5_+_44804791 0.55 ENSDART00000122288
ctsla
cathepsin La
chr8_+_30699429 0.54 ENSDART00000005345
upb1
ureidopropionase, beta
chr20_-_52271015 0.54 ENSDART00000074307
rhpn1
rhophilin, Rho GTPase binding protein 1
chr21_-_42831033 0.53 ENSDART00000160998
stk10
serine/threonine kinase 10
chr15_-_18232712 0.52 ENSDART00000081199
wu:fj20b03
wu:fj20b03
chr4_+_14957360 0.52 ENSDART00000002770
ENSDART00000111882
ENSDART00000148292
tspan33a
tetraspanin 33a
chr16_+_25245857 0.51 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr11_+_18183220 0.51 ENSDART00000113468
LO018315.10

chr2_-_6039757 0.51 ENSDART00000013079
scp2a
sterol carrier protein 2a
chr19_-_41213718 0.51 ENSDART00000077121
pdk4
pyruvate dehydrogenase kinase, isozyme 4
chr3_-_40275096 0.50 ENSDART00000141578
shmt1
serine hydroxymethyltransferase 1 (soluble)
chr4_-_12725513 0.50 ENSDART00000132286
mgst1.2
microsomal glutathione S-transferase 1.2
chr20_-_45722895 0.50 ENSDART00000153273
gpcpd1
glycerophosphocholine phosphodiesterase 1
chr11_-_23459779 0.49 ENSDART00000183935
ENSDART00000184125
ENSDART00000193284
plekha6
pleckstrin homology domain containing, family A member 6
chr12_+_31616412 0.49 ENSDART00000124439
cpn1
carboxypeptidase N, polypeptide 1
chr2_-_51634431 0.49 ENSDART00000165568
pigr
polymeric immunoglobulin receptor
chr9_-_48736388 0.49 ENSDART00000022074
dhrs9
dehydrogenase/reductase (SDR family) member 9
chr15_-_1885247 0.48 ENSDART00000149703
porb
P450 (cytochrome) oxidoreductase b
chr1_-_52222989 0.47 ENSDART00000010236
cnn1a
calponin 1, basic, smooth muscle, a
chr22_+_1821718 0.47 ENSDART00000132220
znf1002
zinc finger protein 1002
chr3_-_40955780 0.47 ENSDART00000130130
cyp3c3
cytochrome P450, family 3, subfamily c, polypeptide 3
chr2_-_17115256 0.47 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr23_+_42454292 0.47 ENSDART00000171459
cyp2aa2
y cytochrome P450, family 2, subfamily AA, polypeptide 2
chr4_-_11403811 0.46 ENSDART00000067272
ENSDART00000140018
pimr173
Pim proto-oncogene, serine/threonine kinase, related 173
chr2_-_20120904 0.46 ENSDART00000186002
ENSDART00000124724
dpydb
dihydropyrimidine dehydrogenase b
chr8_+_39802506 0.46 ENSDART00000018862
hnf1a
HNF1 homeobox a
chr9_-_43071519 0.45 ENSDART00000109099
ttn.2
titin, tandem duplicate 2
chr21_+_38002879 0.45 ENSDART00000065183
cldn2
claudin 2
chr9_+_41080029 0.44 ENSDART00000141179
ENSDART00000019289
zgc:136439
zgc:136439
chr5_-_20123002 0.44 ENSDART00000026516
pxmp2
peroxisomal membrane protein 2
chr10_+_8401929 0.44 ENSDART00000059028
hvcn1
hydrogen voltage-gated channel 1
chr9_-_53062083 0.44 ENSDART00000122155
zmp:0000000936
zmp:0000000936
chr10_-_22803740 0.42 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr1_-_59126139 0.42 ENSDART00000156105
si:ch1073-110a20.7
si:ch1073-110a20.7
chr9_+_13682133 0.42 ENSDART00000175639
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr11_+_3959495 0.42 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr7_+_46019780 0.42 ENSDART00000163991
ccne1
cyclin E1
chr15_-_12258851 0.41 ENSDART00000180656
si:dkey-36i7.3
si:dkey-36i7.3
chr7_-_10560964 0.41 ENSDART00000172761
ENSDART00000170476
mthfs
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr14_-_46238186 0.40 ENSDART00000173245
si:ch211-113d11.6
si:ch211-113d11.6
chr24_+_9881219 0.39 ENSDART00000036204
cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chr12_-_35949936 0.39 ENSDART00000192583
AL954682.1

chr1_-_59139848 0.39 ENSDART00000191863
si:ch1073-110a20.2
si:ch1073-110a20.2
chr13_+_33688474 0.39 ENSDART00000161465
CABZ01087953.1

chr24_-_36727922 0.39 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr11_+_18175893 0.38 ENSDART00000177625
zgc:173545
zgc:173545
chr24_-_2843107 0.38 ENSDART00000165290
cyb5a
cytochrome b5 type A (microsomal)
chr18_-_38216584 0.38 ENSDART00000144622
si:dkey-10o6.2
si:dkey-10o6.2
chr1_-_59130695 0.38 ENSDART00000152560
FP015850.1

chr16_+_16977786 0.38 ENSDART00000043173
ENSDART00000132150
rpl18
ribosomal protein L18
chr17_+_443264 0.37 ENSDART00000159086
zgc:195050
zgc:195050
chr5_-_3960161 0.37 ENSDART00000111453
myo19
myosin XIX
chr1_-_59116617 0.37 ENSDART00000137471
ENSDART00000140490
MFAP4 (1 of many)
si:zfos-2330d3.7
chr11_+_3281899 0.37 ENSDART00000181012
mmp19
matrix metallopeptidase 19
chr24_-_26485098 0.36 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr22_-_17677947 0.36 ENSDART00000139911
tjp3
tight junction protein 3
chr3_+_54581987 0.36 ENSDART00000018071
eif3g
eukaryotic translation initiation factor 3, subunit G
chr12_+_25775734 0.36 ENSDART00000024415
ENSDART00000149198
epas1a
endothelial PAS domain protein 1a
chr10_+_23099890 0.35 ENSDART00000135890
LTN1
si:dkey-175g6.5
chr24_-_33284945 0.35 ENSDART00000155429
ENSDART00000112845
zgc:195173
zgc:195173
chr18_-_16792561 0.34 ENSDART00000145546
ampd3b
adenosine monophosphate deaminase 3b
chr21_-_16219400 0.34 ENSDART00000124871
tnfrsfa
tumor necrosis factor receptor superfamily, member a
chr19_-_9662958 0.34 ENSDART00000041094
clcn1a
chloride channel, voltage-sensitive 1a
chr7_-_7845540 0.33 ENSDART00000166280
cxcl8b.1
chemokine (C-X-C motif) ligand 8b, duplicate 1
chr23_+_27675581 0.33 ENSDART00000127198
rps26
ribosomal protein S26
chr7_+_12950507 0.33 ENSDART00000067629
ENSDART00000158004
saa
serum amyloid A
chr7_-_46019756 0.33 ENSDART00000162583
zgc:162297
zgc:162297
chr3_+_3573696 0.33 ENSDART00000169680
CR589947.2

chr12_+_6002715 0.33 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr23_+_38957738 0.33 ENSDART00000193480
ATP9A
ATPase phospholipid transporting 9A (putative)
chr11_+_7214353 0.33 ENSDART00000156764
nwd1
NACHT and WD repeat domain containing 1
chr20_+_25563105 0.33 ENSDART00000063100
cyp2p6
cytochrome P450, family 2, subfamily P, polypeptide 6
chr7_-_6362460 0.33 ENSDART00000129239
hist1h2a4
histone cluster 1 H2A family member 4
chr23_+_24272421 0.32 ENSDART00000029974
clcnk
chloride channel K
chr25_+_31222069 0.32 ENSDART00000159373
tnni2a.1
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr1_+_52563298 0.32 ENSDART00000142465
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr24_-_25788841 0.32 ENSDART00000132235
klhl24b
kelch-like family member 24b
chr8_+_13503377 0.32 ENSDART00000034740
ENSDART00000167187
fut9d
fucosyltransferase 9d
chr20_-_36679233 0.32 ENSDART00000062908
rpl7l1
ribosomal protein L7-like 1
chr9_-_5318873 0.32 ENSDART00000129308
ACVR1C
activin A receptor type 1C
chr4_-_12723585 0.32 ENSDART00000185639
mgst1.2
microsomal glutathione S-transferase 1.2
chr9_-_46395240 0.32 ENSDART00000169044
si:dkey-79p17.3
si:dkey-79p17.3
chr14_+_32918172 0.32 ENSDART00000182867
lnx2b
ligand of numb-protein X 2b
chr4_-_41209037 0.31 ENSDART00000151948
si:ch211-73m21.1
si:ch211-73m21.1
chr19_-_20403507 0.31 ENSDART00000052603
ENSDART00000137590
dazl
deleted in azoospermia-like
chr14_+_22022441 0.31 ENSDART00000149121
clcf1
cardiotrophin-like cytokine factor 1
chr1_+_31674297 0.31 ENSDART00000044214
wbp1lb
WW domain binding protein 1-like b
chr6_+_8314451 0.31 ENSDART00000147793
ENSDART00000183688
gcdha
glutaryl-CoA dehydrogenase a
chr2_+_24507770 0.31 ENSDART00000154802
ENSDART00000052063
rps28
ribosomal protein S28
chr17_-_34952562 0.30 ENSDART00000021128
kidins220a
kinase D-interacting substrate 220a
chr17_-_14613711 0.30 ENSDART00000157345
sdsl
serine dehydratase-like
chr24_-_40700596 0.30 ENSDART00000162635
smyhc2
slow myosin heavy chain 2
chr12_+_47081783 0.30 ENSDART00000158568
mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr9_+_2522797 0.30 ENSDART00000186786
ENSDART00000147034
gpr155a
G protein-coupled receptor 155a
chr3_-_29870848 0.30 ENSDART00000186457
rpl3
ribosomal protein L3
chr4_-_16345227 0.30 ENSDART00000079521
kera
keratocan
chr24_-_38644937 0.30 ENSDART00000170194
slc6a16b
solute carrier family 6, member 16b
chr23_-_36884012 0.29 ENSDART00000137282
ube2j2
ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)
chr10_-_17550239 0.29 ENSDART00000057513
ska1
spindle and kinetochore associated complex subunit 1
chr25_-_18730697 0.29 ENSDART00000182475
si:dkeyp-93a5.2
si:dkeyp-93a5.2
chr23_-_7674902 0.29 ENSDART00000185612
ENSDART00000180524
plagl2
pleiomorphic adenoma gene-like 2
chr21_-_40630650 0.29 ENSDART00000172706
pcyt1bb
phosphate cytidylyltransferase 1, choline, beta b
chr24_-_32582378 0.29 ENSDART00000066590
rdh12l
retinol dehydrogenase 12, like
chr4_+_71989418 0.28 ENSDART00000170996
parp11
poly(ADP-ribose) polymerase family member 11
chr22_-_6420239 0.28 ENSDART00000148385
zgc:171699
zgc:171699
chr6_-_49510553 0.28 ENSDART00000166238
rplp2
ribosomal protein, large P2
chr5_+_27442247 0.28 ENSDART00000184129
loxl2b
lysyl oxidase-like 2b
chr18_-_21640389 0.28 ENSDART00000100857
slc38a8a
solute carrier family 38, member 8a
chr25_+_20188769 0.28 ENSDART00000142781
cald1b
caldesmon 1b
chr20_-_33961697 0.28 ENSDART00000061765
selp
selectin P
chr16_+_44906324 0.28 ENSDART00000074960
cd22
cd22 molecule
chr2_+_17055069 0.28 ENSDART00000115078
thpo
thrombopoietin
chr6_-_39649504 0.28 ENSDART00000179960
ENSDART00000190951
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr8_+_25351863 0.28 ENSDART00000034092
dnase1l1l
deoxyribonuclease I-like 1-like
chr7_-_39738460 0.27 ENSDART00000052201
ccdc96
coiled-coil domain containing 96
chr10_+_4924388 0.27 ENSDART00000108595
slc46a2
solute carrier family 46 member 2
chr1_+_17892944 0.27 ENSDART00000013021
tlr3
toll-like receptor 3
chr5_+_4564233 0.27 ENSDART00000193435
CABZ01058647.1

chr24_-_32582880 0.27 ENSDART00000186307
rdh12l
retinol dehydrogenase 12, like
chr21_-_41065369 0.27 ENSDART00000143749
larsb
leucyl-tRNA synthetase b
chr2_+_49667767 0.26 ENSDART00000191013
ENSDART00000193757
ENSDART00000187134
ENSDART00000189100
BX323861.3

chr5_+_6955900 0.26 ENSDART00000099417
CABZ01041962.1

chr13_-_4986364 0.26 ENSDART00000168465
nolc1
nucleolar and coiled-body phosphoprotein 1
chr11_+_31324335 0.26 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr24_-_26369185 0.26 ENSDART00000080039
lrrc31
leucine rich repeat containing 31
chr6_+_8315050 0.26 ENSDART00000189987
gcdha
glutaryl-CoA dehydrogenase a
chr12_-_16720432 0.26 ENSDART00000152261
ENSDART00000152154
si:dkey-26g8.4
si:dkey-26g8.4
chr23_-_40814080 0.26 ENSDART00000135713
si:dkeyp-27c8.1
si:dkeyp-27c8.1
chr25_-_36361697 0.26 ENSDART00000152388
si:ch211-113a14.22
si:ch211-113a14.22
chr14_-_9281232 0.26 ENSDART00000054693
asb12b
ankyrin repeat and SOCS box-containing 12b
chr18_+_17493859 0.26 ENSDART00000090754
si:dkey-102f14.5
si:dkey-102f14.5
chr6_-_43449013 0.26 ENSDART00000122423
eevs
2-epi-5-epi-valiolone synthase
chr23_+_9220436 0.26 ENSDART00000033663
ENSDART00000139870
rps21
ribosomal protein S21

Network of associatons between targets according to the STRING database.

First level regulatory network of cebpa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.3 1.8 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.3 0.8 GO:0009258 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 1.0 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.2 0.6 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.2 0.6 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.2 0.5 GO:0006565 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.2 2.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.6 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 0.5 GO:0002526 acute inflammatory response(GO:0002526) acute-phase response(GO:0006953)
0.1 1.0 GO:0032570 response to progesterone(GO:0032570)
0.1 1.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.8 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 2.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.6 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.3 GO:0032602 chemokine production(GO:0032602) toll-like receptor 3 signaling pathway(GO:0034138)
0.1 0.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.4 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 0.3 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.3 GO:0046436 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.3 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 0.2 GO:0060688 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.2 GO:0097240 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.4 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.1 0.9 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:0006032 chitin catabolic process(GO:0006032)
0.1 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.7 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.2 GO:0032197 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.4 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.2 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.8 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.2 GO:1904353 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.3 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.9 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.3 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 1.2 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 1.0 GO:0051180 vitamin transport(GO:0051180)
0.0 0.2 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.6 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.1 GO:2000376 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.0 0.4 GO:0030104 water homeostasis(GO:0030104)
0.0 0.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.5 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.4 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0046102 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 0.2 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.1 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.8 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 0.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0042558 pteridine-containing compound metabolic process(GO:0042558)
0.0 0.1 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 1.0 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.4 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.1 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.0 0.5 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.2 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0001541 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.5 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.9 GO:0072376 protein activation cascade(GO:0072376)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0032048 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.2 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.2 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0060021 palate development(GO:0060021)
0.0 0.1 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.5 GO:0097268 cytoophidium(GO:0097268)
0.1 0.3 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.1 0.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.2 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0005880 nuclear microtubule(GO:0005880)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0044279 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 20.2 GO:0005615 extracellular space(GO:0005615)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 2.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 1.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.3 0.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.3 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.3 1.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.3 0.8 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 0.8 GO:0042806 fucose binding(GO:0042806)
0.2 1.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 1.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.5 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.2 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.6 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.6 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 0.5 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.5 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.2 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 0.3 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.7 GO:0004568 chitinase activity(GO:0004568)
0.1 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0034246 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 1.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 6.5 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.1 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.0 0.5 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 2.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.6 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.2 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.7 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 1.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0001032 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.0 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 2.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases