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PRJNA207719: Tissue specific transcriptome profiling

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Results for dbpa+dbpb+hlfa

Z-value: 1.07

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Transcription factors associated with dbpa+dbpb+hlfa

Gene Symbol Gene ID Gene Info
dbpb
ENSDARG00000057652 D site albumin promoter binding protein b
dbpa
ENSDARG00000063014 D site albumin promoter binding protein a
hlfa
ENSDARG00000074752 HLF transcription factor, PAR bZIP family member a
dbpb
ENSDARG00000116703 D site albumin promoter binding protein b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dbpbdr11_v1_chr16_-_13612650_136126500.951.5e-02Click!
hlfadr11_v1_chr3_-_11624694_116246940.932.3e-02Click!
dbpadr11_v1_chr19_-_10196370_101963700.922.8e-02Click!

Activity profile of dbpa+dbpb+hlfa motif

Sorted Z-values of dbpa+dbpb+hlfa motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_38079261 1.68 ENSDART00000105662
crp1
C-reactive protein 1
chr16_+_34523515 1.48 ENSDART00000041007
stmn1b
stathmin 1b
chr21_-_43550120 1.32 ENSDART00000151627
si:ch73-362m14.2
si:ch73-362m14.2
chr2_-_54387550 1.31 ENSDART00000097388
napgb
N-ethylmaleimide-sensitive factor attachment protein, gamma b
chr3_-_46818001 1.26 ENSDART00000166505
elavl3
ELAV like neuron-specific RNA binding protein 3
chr3_-_28665291 1.21 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr23_-_27345425 1.11 ENSDART00000022042
ENSDART00000191870
scn8aa
sodium channel, voltage gated, type VIII, alpha subunit a
chr8_+_28900689 1.07 ENSDART00000141634
grid2
glutamate receptor, ionotropic, delta 2
chr1_+_31112436 1.00 ENSDART00000075340
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr12_-_26383242 0.99 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr4_-_5302866 0.90 ENSDART00000138590
SNAP91 (1 of many)
si:ch211-214j24.9
chr23_+_37323962 0.90 ENSDART00000102881
fam43b
family with sequence similarity 43, member B
chr25_+_7784582 0.87 ENSDART00000155016
dgkzb
diacylglycerol kinase, zeta b
chr19_-_9712530 0.86 ENSDART00000134816
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr25_+_15354095 0.84 ENSDART00000090397
kiaa1549la
KIAA1549-like a
chr19_+_46259619 0.83 ENSDART00000158032
grinaa
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr9_-_1702648 0.80 ENSDART00000102934
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr3_-_31804481 0.79 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr12_+_28574863 0.76 ENSDART00000153284
tbkbp1
TBK1 binding protein 1
chr23_+_45579497 0.76 ENSDART00000110381
egr4
early growth response 4
chr20_-_40717900 0.73 ENSDART00000181663
cx43
connexin 43
chr4_-_5302162 0.72 ENSDART00000177099
SNAP91 (1 of many)
si:ch211-214j24.9
chr12_-_19862912 0.71 ENSDART00000145788
shisa9a
shisa family member 9a
chr25_-_1235457 0.69 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr19_+_342094 0.69 ENSDART00000151013
ENSDART00000187622
ensaa
endosulfine alpha a
chr6_+_41255485 0.69 ENSDART00000042683
ENSDART00000186013
cadpsb
Ca2+-dependent activator protein for secretion b
chr16_+_46111849 0.68 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr11_-_10770053 0.66 ENSDART00000179213
slc4a10a
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr8_+_26874924 0.65 ENSDART00000141794
rimkla
ribosomal modification protein rimK-like family member A
chr17_-_20979077 0.65 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr20_-_45661049 0.64 ENSDART00000124582
ENSDART00000131251
napbb
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr9_-_35069645 0.64 ENSDART00000122679
ENSDART00000077908
ENSDART00000077894
ENSDART00000125536
appb
amyloid beta (A4) precursor protein b
chr12_-_3753131 0.62 ENSDART00000129668
fam57bb
family with sequence similarity 57, member Bb
chr24_-_32665283 0.62 ENSDART00000038364
ca2
carbonic anhydrase II
chr14_-_9199968 0.61 ENSDART00000146113
arhgef9b
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr7_+_38717624 0.61 ENSDART00000132522
syt13
synaptotagmin XIII
chr8_+_7975745 0.61 ENSDART00000137920
si:ch211-169p10.1
si:ch211-169p10.1
chr18_-_14941840 0.58 ENSDART00000091729
mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr6_+_37754763 0.58 ENSDART00000110770
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr21_-_32467799 0.57 ENSDART00000007675
ENSDART00000133099
zgc:123105
zgc:123105
chr7_+_69528850 0.57 ENSDART00000109507
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1
chr5_+_32162684 0.57 ENSDART00000134472
taok3b
TAO kinase 3b
chr16_+_47207691 0.56 ENSDART00000062507
ica1
islet cell autoantigen 1
chr5_+_3501859 0.56 ENSDART00000080486
ywhag1
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr10_-_24371312 0.56 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr16_+_14029283 0.56 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr15_-_20939579 0.56 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr20_+_1121458 0.55 ENSDART00000064472
pnrc1
proline-rich nuclear receptor coactivator 1
chr3_-_36932515 0.55 ENSDART00000111981
ENSDART00000188470
cntnap1
contactin associated protein 1
chr17_-_43466317 0.55 ENSDART00000155313
hspa4l
heat shock protein 4 like
chr18_-_47662696 0.53 ENSDART00000184260
CABZ01073963.1

chr7_-_38792543 0.50 ENSDART00000157416
si:dkey-23n7.10
si:dkey-23n7.10
chr23_-_33361425 0.50 ENSDART00000031638
slc48a1a
solute carrier family 48 (heme transporter), member 1a
chr11_+_23933016 0.49 ENSDART00000000486
cntn2
contactin 2
chr9_-_42418470 0.49 ENSDART00000144353
calcrla
calcitonin receptor-like a
chr22_+_27090136 0.47 ENSDART00000136770
si:dkey-246e1.3
si:dkey-246e1.3
chr25_-_13490744 0.47 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr5_+_27583117 0.47 ENSDART00000180340
zmat4a
zinc finger, matrin-type 4a
chr25_-_11088839 0.46 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr21_-_42202792 0.46 ENSDART00000124708
gabra6b
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr7_+_38278860 0.45 ENSDART00000016265
lrp3
low density lipoprotein receptor-related protein 3
chr5_-_29488245 0.45 ENSDART00000047719
ENSDART00000141154
ENSDART00000171165
cacna1ba
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
chr24_-_39772045 0.43 ENSDART00000087441
GFOD1
si:ch211-276f18.2
chr6_+_23810529 0.43 ENSDART00000166921
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr16_-_45069882 0.43 ENSDART00000058384
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr3_-_21348478 0.42 ENSDART00000114906
fam171a2a
family with sequence similarity 171, member A2a
chr9_-_18742704 0.41 ENSDART00000145401
tsc22d1
TSC22 domain family, member 1
chr12_-_46959990 0.41 ENSDART00000084557
lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr20_+_2950005 0.40 ENSDART00000135919
amd1
adenosylmethionine decarboxylase 1
chr9_-_9225980 0.39 ENSDART00000180301
cbsb
cystathionine-beta-synthase b
chr10_-_2527342 0.38 ENSDART00000184168
CU856539.1

chr4_-_2727491 0.37 ENSDART00000141760
ENSDART00000039083
ENSDART00000134442
slco1c1
solute carrier organic anion transporter family, member 1C1
chr5_+_31860043 0.37 ENSDART00000036235
ENSDART00000140541
iscub
iron-sulfur cluster assembly enzyme b
chr20_-_15132151 0.36 ENSDART00000063884
si:dkey-239i20.4
si:dkey-239i20.4
chr6_+_23809163 0.35 ENSDART00000170402
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr1_+_2128970 0.34 ENSDART00000180074
ENSDART00000022019
ENSDART00000098059
mbnl2
muscleblind-like splicing regulator 2
chr22_+_10660140 0.33 ENSDART00000105835
ENSDART00000038511
tusc2b
tumor suppressor candidate 2b
chr11_+_43751263 0.33 ENSDART00000163843
zgc:153431
zgc:153431
chr17_+_15845765 0.31 ENSDART00000130881
ENSDART00000074936
gabrr2a
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr7_-_41420226 0.30 ENSDART00000074155
abcf2b
ATP-binding cassette, sub-family F (GCN20), member 2b
chr19_+_7549854 0.29 ENSDART00000138866
ENSDART00000151758
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr13_+_23157053 0.29 ENSDART00000162359
sorbs1
sorbin and SH3 domain containing 1
chr21_-_5007109 0.29 ENSDART00000187042
ENSDART00000097796
ENSDART00000146766
rnf165a
ring finger protein 165a
chr5_+_69808763 0.28 ENSDART00000143482
fsd1l
fibronectin type III and SPRY domain containing 1-like
chr22_-_881725 0.28 ENSDART00000035514
cept1b
choline/ethanolamine phosphotransferase 1b
chr24_+_18948665 0.28 ENSDART00000106186
prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr19_-_25113660 0.28 ENSDART00000035538
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr21_-_32467099 0.28 ENSDART00000186354
zgc:123105
zgc:123105
chr8_+_8712446 0.28 ENSDART00000158674
elk1
ELK1, member of ETS oncogene family
chr9_+_33788626 0.27 ENSDART00000088469
kdm6a
lysine (K)-specific demethylase 6A
chr19_-_7291733 0.27 ENSDART00000015559
sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr9_-_18743012 0.26 ENSDART00000131626
tsc22d1
TSC22 domain family, member 1
chr19_+_41080240 0.26 ENSDART00000087295
ppp1r9a
protein phosphatase 1, regulatory subunit 9A
chr6_+_22025806 0.26 ENSDART00000151240
ZXDC
si:dkey-156n14.3
chr5_-_50638905 0.26 ENSDART00000180842
mctp1a
multiple C2 domains, transmembrane 1a
chr11_-_7078392 0.25 ENSDART00000112156
ENSDART00000188556
si:ch211-253b8.5
si:ch211-253b8.5
chr18_-_39288894 0.25 ENSDART00000186216
mapk6
mitogen-activated protein kinase 6
chr7_+_23580082 0.24 ENSDART00000183245
si:dkey-172j4.3
si:dkey-172j4.3
chr2_-_32486080 0.24 ENSDART00000110821
ttc19
tetratricopeptide repeat domain 19
chr9_-_13871935 0.24 ENSDART00000146597
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr15_-_22074315 0.24 ENSDART00000149830
drd2a
dopamine receptor D2a
chr22_+_15973122 0.24 ENSDART00000144545
rc3h1a
ring finger and CCCH-type domains 1a
chr6_-_7726849 0.23 ENSDART00000151511
slc25a38b
solute carrier family 25, member 38b
chr8_-_29851706 0.23 ENSDART00000149297
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr18_+_507618 0.22 ENSDART00000159464
nedd4a
neural precursor cell expressed, developmentally down-regulated 4a
chr21_-_39058490 0.22 ENSDART00000114885
aldh3a2b
aldehyde dehydrogenase 3 family, member A2b
chr19_-_44054930 0.22 ENSDART00000151084
ENSDART00000150991
ENSDART00000005191
uqcrb
ubiquinol-cytochrome c reductase binding protein
chr15_-_24960730 0.22 ENSDART00000109990
ENSDART00000186706
abhd15a
abhydrolase domain containing 15a
chr2_-_49860723 0.21 ENSDART00000083690
blvra
biliverdin reductase A
chr10_+_18877362 0.21 ENSDART00000138334
ppp2r2ab
protein phosphatase 2, regulatory subunit B, alpha b
chr20_-_20610812 0.21 ENSDART00000181870
ppm1ab
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr21_+_43178831 0.21 ENSDART00000151512
aff4
AF4/FMR2 family, member 4
chr6_+_23809501 0.20 ENSDART00000168701
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr22_-_18491813 0.20 ENSDART00000105419
si:ch211-212d10.2
si:ch211-212d10.2
chr12_+_15002757 0.20 ENSDART00000135036
mylpfb
myosin light chain, phosphorylatable, fast skeletal muscle b
chr18_-_18850302 0.20 ENSDART00000131965
ENSDART00000167624
tgm2l
transglutaminase 2, like
chr21_+_7188943 0.20 ENSDART00000172174
agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr7_+_52761841 0.20 ENSDART00000111444
ppip5k1a
diphosphoinositol pentakisphosphate kinase 1a
chr18_+_26899316 0.19 ENSDART00000050230
tspan3a
tetraspanin 3a
chr25_+_28893615 0.19 ENSDART00000156994
ENSDART00000075151
amn1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr25_-_16826219 0.19 ENSDART00000191299
ENSDART00000188504
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr17_-_7371564 0.19 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr6_-_14292307 0.18 ENSDART00000177852
ENSDART00000061745
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr6_+_12326267 0.18 ENSDART00000155101
si:dkey-276j7.3
si:dkey-276j7.3
chr20_-_20611063 0.18 ENSDART00000063492
ppm1ab
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr17_-_8268406 0.18 ENSDART00000149873
ENSDART00000064668
ENSDART00000148403
ahi1
Abelson helper integration site 1
chr6_-_29612269 0.18 ENSDART00000104293
pex5la
peroxisomal biogenesis factor 5-like a
chr10_-_31175744 0.18 ENSDART00000191728
pknox2
pbx/knotted 1 homeobox 2
chr20_-_20355577 0.18 ENSDART00000018500
hif1ab
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b
chr10_+_9595575 0.18 ENSDART00000091780
ENSDART00000184287
rc3h2
ring finger and CCCH-type domains 2
chr6_-_41085692 0.18 ENSDART00000181463
srsf3a
serine/arginine-rich splicing factor 3a
chr16_-_20294236 0.17 ENSDART00000059623
plekha8
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr9_+_33788389 0.17 ENSDART00000144623
kdm6a
lysine (K)-specific demethylase 6A
chr16_-_7828838 0.16 ENSDART00000191434
ENSDART00000108653
tcaim
T cell activation inhibitor, mitochondrial
chr23_-_29812667 0.16 ENSDART00000006120
pik3cd
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr17_-_25831569 0.16 ENSDART00000148743
hhat
hedgehog acyltransferase
chr8_-_32497815 0.15 ENSDART00000122359
si:dkey-164f24.2
si:dkey-164f24.2
chr7_+_17716601 0.15 ENSDART00000173792
ENSDART00000080825
rtn3
reticulon 3
chr5_-_43935119 0.14 ENSDART00000142271
si:ch211-204c21.1
si:ch211-204c21.1
chr5_-_43935460 0.14 ENSDART00000166152
ENSDART00000188969
si:ch211-204c21.1
si:ch211-204c21.1
chr16_+_25245857 0.14 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr23_+_33963619 0.14 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr23_+_9522781 0.14 ENSDART00000136486
osbpl2b
oxysterol binding protein-like 2b
chr3_-_31875138 0.13 ENSDART00000155298
limd2
LIM domain containing 2
chr10_+_10210455 0.13 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr5_-_69437422 0.13 ENSDART00000073676
isca1
iron-sulfur cluster assembly 1
chr20_-_1151265 0.13 ENSDART00000012376
gabrr1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr21_-_39566854 0.13 ENSDART00000020174
dynll2b
dynein, light chain, LC8-type 2b
chr16_-_35427060 0.12 ENSDART00000172294
ctps1b
CTP synthase 1b
chr21_-_36948 0.12 ENSDART00000181230
JMY
junction mediating and regulatory protein, p53 cofactor
chr12_-_9538578 0.12 ENSDART00000066445
nudt13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr18_-_15551360 0.12 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr8_+_7801060 0.12 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr25_-_2081371 0.12 ENSDART00000104915
ENSDART00000156925
wnt7bb
wingless-type MMTV integration site family, member 7Bb
chr8_-_32497581 0.11 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
si:dkey-164f24.2
chr9_-_6927587 0.11 ENSDART00000059092
tmem182a
transmembrane protein 182a
chr18_+_19883325 0.11 ENSDART00000182625
zgc:162898
zgc:162898
chr15_+_21882419 0.11 ENSDART00000157216
si:dkey-103g5.4
si:dkey-103g5.4
chr1_-_59411901 0.11 ENSDART00000167015
si:ch211-188p14.4
si:ch211-188p14.4
chr17_-_6076084 0.10 ENSDART00000058890
ephx2
epoxide hydrolase 2, cytoplasmic
chr8_-_31716302 0.10 ENSDART00000061832
si:dkey-46a10.3
si:dkey-46a10.3
chr20_+_51471921 0.09 ENSDART00000150030
tlr5b
toll-like receptor 5b
chr19_+_9032073 0.09 ENSDART00000127755
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr8_+_247163 0.09 ENSDART00000122378
cep120
centrosomal protein 120
chr23_-_30960506 0.09 ENSDART00000142661
osbpl2a
oxysterol binding protein-like 2a
chr11_+_16153207 0.09 ENSDART00000192356
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr11_+_24900123 0.08 ENSDART00000044987
ENSDART00000148023
timm17a
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr22_+_20720808 0.07 ENSDART00000171321
si:dkey-211f22.5
si:dkey-211f22.5
chr7_+_4162994 0.07 ENSDART00000172800
si:ch211-63p21.1
si:ch211-63p21.1
chr2_+_44348473 0.07 ENSDART00000155166
ENSDART00000098146
zgc:152670
zgc:152670
chr8_+_1187928 0.07 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr13_+_30035253 0.07 ENSDART00000181303
ENSDART00000057525
ENSDART00000136622
dnajb12a
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr3_+_24094581 0.07 ENSDART00000138270
ENSDART00000131509
copz2
coatomer protein complex, subunit zeta 2
chr12_+_3571770 0.06 ENSDART00000164707
ENSDART00000189819
coa3a
cytochrome C oxidase assembly factor 3a
chr22_-_20720427 0.06 ENSDART00000105532
oaz1a
ornithine decarboxylase antizyme 1a
chr10_-_20523405 0.06 ENSDART00000114824
ddhd2
DDHD domain containing 2
chr13_-_18195942 0.05 ENSDART00000079902
slc25a16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr9_-_9732212 0.05 ENSDART00000092884
lrrc58b
leucine rich repeat containing 58b
chr20_-_35246150 0.05 ENSDART00000090549
fzd3a
frizzled class receptor 3a
chr8_+_17884569 0.05 ENSDART00000134660
slc44a5b
solute carrier family 44, member 5b
chr2_+_49860722 0.04 ENSDART00000144060
rpl37
ribosomal protein L37
chr12_-_20584413 0.04 ENSDART00000170923
FP885542.2

chr3_+_33440615 0.04 ENSDART00000146005
gtpbp1
GTP binding protein 1
chr6_-_40455109 0.04 ENSDART00000103878
vhl
von Hippel-Lindau tumor suppressor
chr7_-_41693004 0.04 ENSDART00000121509
malrd1
MAM and LDL receptor class A domain containing 1
chr22_-_21176269 0.04 ENSDART00000112839
rex1bd
required for excision 1-B domain containing
chr22_-_10605045 0.03 ENSDART00000184812
bap1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr4_+_21867522 0.03 ENSDART00000140400
acss3
acyl-CoA synthetase short chain family member 3
chr7_+_73295890 0.03 ENSDART00000174331
ENSDART00000174250
CABZ01083442.1

chr1_-_35928942 0.03 ENSDART00000033566
smad1
SMAD family member 1
chr15_-_21849300 0.02 ENSDART00000183603
laynb
layilin b
chr3_-_32927516 0.02 ENSDART00000140117
aoc2
amine oxidase, copper containing 2
chr25_+_32473277 0.02 ENSDART00000146451
sqor
sulfide quinone oxidoreductase
chr23_-_19486571 0.02 ENSDART00000009092
fam208ab
family with sequence similarity 208, member Ab
chr15_+_15232855 0.01 ENSDART00000033904
ENSDART00000139263
med29
mediator complex subunit 29
chr12_+_8003872 0.01 ENSDART00000180300
ENSDART00000126661
rhobtb1
Rho-related BTB domain containing 1
chr17_+_43013171 0.01 ENSDART00000055541
gskip
gsk3b interacting protein
chr10_-_25591194 0.01 ENSDART00000131640
tiam1a
T cell lymphoma invasion and metastasis 1a
chr11_+_39135050 0.00 ENSDART00000180571
ENSDART00000189685
cdc42
cell division cycle 42
chr16_-_54800202 0.00 ENSDART00000059560
ENSDART00000161833
khdc4
KH domain containing 4, pre-mRNA splicing factor

Network of associatons between targets according to the STRING database.

First level regulatory network of dbpa+dbpb+hlfa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.5 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 0.6 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 0.5 GO:0006089 lactate metabolic process(GO:0006089)
0.2 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.4 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 0.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.2 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.1 0.3 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 1.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.5 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.5 GO:0032288 myelin assembly(GO:0032288)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.6 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0008216 spermidine metabolic process(GO:0008216)
0.0 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.0 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0 0.6 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.7 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.5 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.5 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.9 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.2 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 1.4 GO:0016579 protein deubiquitination(GO:0016579)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.5 GO:0033010 paranodal junction(GO:0033010)
0.1 0.3 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.9 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.9 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 0.6 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.2 0.5 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 1.0 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.5 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 0.2 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.3 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.5 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.0 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.4 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)