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PRJNA207719: Tissue specific transcriptome profiling

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Results for dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

Z-value: 0.95

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Transcription factors associated with dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

Gene Symbol Gene ID Gene Info
dlx2b
ENSDARG00000017174 distal-less homeobox 2b
dlx2a
ENSDARG00000079964 distal-less homeobox 2a
dlx2b
ENSDARG00000116017 distal-less homeobox 2b
dlx4a
ENSDARG00000011956 distal-less homeobox 4a
dlx6a
ENSDARG00000042291 distal-less homeobox 6a
dlx4b
ENSDARG00000071560 distal-less homeobox 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx4bdr11_v1_chr12_-_5728755_5728755-0.791.1e-01Click!
dlx4adr11_v1_chr3_+_34670076_34670076-0.761.3e-01Click!
dlx6adr11_v1_chr19_+_41419519_414195190.553.4e-01Click!
dlx2adr11_v1_chr9_-_3400727_34007290.098.9e-01Click!
dlx2bdr11_v1_chr1_-_30979707_309797070.019.8e-01Click!

Activity profile of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a motif

Sorted Z-values of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_28731379 1.03 ENSDART00000047378
cort
cortistatin
chr20_-_45060241 0.76 ENSDART00000185227
klhl29
kelch-like family member 29
chr12_+_24342303 0.75 ENSDART00000111239
nrxn1a
neurexin 1a
chr24_-_24849091 0.70 ENSDART00000133649
ENSDART00000038290
crhb
corticotropin releasing hormone b
chrM_+_9052 0.68 ENSDART00000093612
mt-atp6
ATP synthase 6, mitochondrial
chr17_-_20717845 0.68 ENSDART00000150037
ank3b
ankyrin 3b
chr20_-_9462433 0.68 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr16_+_5774977 0.68 ENSDART00000134202
ccka
cholecystokinin a
chr13_+_38430466 0.66 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr20_-_28800999 0.62 ENSDART00000049462
rab15
RAB15, member RAS oncogene family
chr18_+_7204378 0.60 ENSDART00000142905
vwf
von Willebrand factor
chr7_+_30787903 0.60 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr4_+_12615836 0.59 ENSDART00000003583
lmo3
LIM domain only 3
chr6_+_39232245 0.58 ENSDART00000187351
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr5_+_19314574 0.58 ENSDART00000133247
rusc2
RUN and SH3 domain containing 2
chr25_+_29662411 0.57 ENSDART00000077445
pim3
Pim-3 proto-oncogene, serine/threonine kinase
chr10_-_34871737 0.56 ENSDART00000138755
dclk1a
doublecortin-like kinase 1a
chr6_-_54826061 0.54 ENSDART00000149982
tnni1b
troponin I type 1b (skeletal, slow)
chr9_-_21918963 0.53 ENSDART00000090782
lmo7a
LIM domain 7a
chr1_-_44701313 0.52 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr20_-_29420713 0.51 ENSDART00000147464
ryr3
ryanodine receptor 3
chr13_-_31435137 0.48 ENSDART00000057441
rtn1a
reticulon 1a
chr15_-_6247775 0.48 ENSDART00000148350
dscamb
Down syndrome cell adhesion molecule b
chr22_-_7129631 0.47 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr14_-_30587814 0.47 ENSDART00000144912
ENSDART00000149714
tmem265
transmembrane protein 265
chr15_+_15856178 0.46 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr7_-_28148310 0.45 ENSDART00000044208
lmo1
LIM domain only 1
chr1_+_16397063 0.44 ENSDART00000159794
micu3a
mitochondrial calcium uptake family, member 3a
chr1_+_16396870 0.43 ENSDART00000189245
ENSDART00000113266
micu3a
mitochondrial calcium uptake family, member 3a
chr19_-_7358184 0.43 ENSDART00000092379
oxr1b
oxidation resistance 1b
chr13_-_36911118 0.43 ENSDART00000048739
trim9
tripartite motif containing 9
chr6_+_52804267 0.43 ENSDART00000065681
matn4
matrilin 4
chrM_+_9735 0.43 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr10_+_42690374 0.42 ENSDART00000123496
rhobtb2b
Rho-related BTB domain containing 2b
chr1_+_11977426 0.42 ENSDART00000103399
tspan5b
tetraspanin 5b
chr17_+_24687338 0.41 ENSDART00000135794
selenon
selenoprotein N
chr2_-_33645411 0.40 ENSDART00000114663
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr22_-_11136625 0.40 ENSDART00000016873
ENSDART00000125561
atp6ap2
ATPase H+ transporting accessory protein 2
chr14_+_34971554 0.39 ENSDART00000184271
rnf145a
ring finger protein 145a
chr11_-_6974022 0.39 ENSDART00000172851
COMP
si:ch211-43f4.1
chr4_+_7391110 0.39 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr20_-_32270866 0.38 ENSDART00000153140
armc2
armadillo repeat containing 2
chr20_+_34933183 0.37 ENSDART00000062738
snap25a
synaptosomal-associated protein, 25a
chr9_-_20372977 0.36 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr17_-_21162821 0.36 ENSDART00000157283
abhd12
abhydrolase domain containing 12
chr17_-_16965809 0.35 ENSDART00000153697
nrxn3a
neurexin 3a
chr15_+_31806303 0.35 ENSDART00000155902
frya
furry homolog a (Drosophila)
chr8_-_46894362 0.35 ENSDART00000111124
acot7
acyl-CoA thioesterase 7
chr20_+_19238382 0.35 ENSDART00000136757
fndc4a
fibronectin type III domain containing 4a
chr12_+_34953038 0.35 ENSDART00000187022
ENSDART00000123988
ENSDART00000027034
qki2
QKI, KH domain containing, RNA binding 2
chr2_-_16380283 0.34 ENSDART00000149992
si:dkey-231j24.3
si:dkey-231j24.3
chr17_-_44247707 0.34 ENSDART00000126097
otx2b
orthodenticle homeobox 2b
chr10_+_29698467 0.34 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr19_-_32804535 0.34 ENSDART00000175613
ENSDART00000052098
nt5c1aa
5'-nucleotidase, cytosolic IAa
chr16_+_35661771 0.33 ENSDART00000161393
map7d1a
MAP7 domain containing 1a
chr6_-_41229787 0.32 ENSDART00000065013
synpr
synaptoporin
chr15_+_42397125 0.32 ENSDART00000169751
tiam1b
T cell lymphoma invasion and metastasis 1b
chr13_-_44630111 0.31 ENSDART00000110092
mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr22_-_20166660 0.31 ENSDART00000085913
ENSDART00000188241
btbd2a
BTB (POZ) domain containing 2a
chr3_+_34919810 0.31 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr23_+_20563779 0.30 ENSDART00000146008
camkvl
CaM kinase-like vesicle-associated, like
chr17_-_29119362 0.30 ENSDART00000104204
foxg1a
forkhead box G1a
chr8_-_19051906 0.30 ENSDART00000089024
sema6bb
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr2_+_50608099 0.30 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr17_+_23298928 0.30 ENSDART00000153652
zgc:165461
zgc:165461
chr4_+_26629368 0.30 ENSDART00000183575
iqsec3a
IQ motif and Sec7 domain 3a
chr6_-_14292307 0.30 ENSDART00000177852
ENSDART00000061745
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr16_+_13818743 0.30 ENSDART00000090191
flcn
folliculin
chr16_-_17197546 0.29 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr16_+_13818500 0.29 ENSDART00000135245
flcn
folliculin
chr4_+_11384891 0.29 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr3_-_46817499 0.28 ENSDART00000013717
elavl3
ELAV like neuron-specific RNA binding protein 3
chr10_+_3049636 0.27 ENSDART00000081794
ENSDART00000183167
ENSDART00000191634
ENSDART00000183514
rasgrf2a
Ras protein-specific guanine nucleotide-releasing factor 2a
chr17_-_12389259 0.27 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr14_+_23184517 0.27 ENSDART00000181410
enox2
ecto-NOX disulfide-thiol exchanger 2
chr18_+_9637744 0.27 ENSDART00000190171
pclob
piccolo presynaptic cytomatrix protein b
chr23_-_38497705 0.26 ENSDART00000109493
tshz2
teashirt zinc finger homeobox 2
chr1_-_50859053 0.26 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr22_+_5176693 0.26 ENSDART00000160927
cers1
ceramide synthase 1
chr11_-_37509001 0.26 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr25_+_29160102 0.26 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr1_+_52929185 0.26 ENSDART00000147683
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr16_+_20161805 0.25 ENSDART00000192146
c16h2orf66
chromosome 16 C2orf66 homolog
chr7_-_25895189 0.24 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr16_+_17389116 0.24 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr10_+_41765616 0.23 ENSDART00000170682
rnf34b
ring finger protein 34b
chr16_-_30434279 0.23 ENSDART00000018504
zgc:77086
zgc:77086
chr16_-_12953739 0.23 ENSDART00000103894
cacng8b
calcium channel, voltage-dependent, gamma subunit 8b
chr3_-_34296361 0.23 ENSDART00000181485
ENSDART00000113726
tnrc6c1
trinucleotide repeat containing 6C1
chr18_-_1185772 0.23 ENSDART00000143245
nptnb
neuroplastin b
chr6_-_6487876 0.23 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr20_+_30445971 0.22 ENSDART00000153150
myt1la
myelin transcription factor 1-like, a
chr21_-_42100471 0.22 ENSDART00000166148
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr16_-_19890303 0.21 ENSDART00000147161
ENSDART00000079159
hdac9b
histone deacetylase 9b
chr9_+_17983463 0.21 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr20_-_46362606 0.21 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr15_-_22074315 0.20 ENSDART00000149830
drd2a
dopamine receptor D2a
chr22_+_5176255 0.20 ENSDART00000092647
cers1
ceramide synthase 1
chr11_+_30057762 0.20 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr19_+_46158078 0.20 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr11_-_8126223 0.20 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
ttll7
tubulin tyrosine ligase-like family, member 7
chr18_+_9362455 0.19 ENSDART00000187025
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr15_-_16177603 0.19 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr21_+_29077509 0.19 ENSDART00000128561
ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr16_-_13623928 0.19 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr20_-_27711970 0.18 ENSDART00000139637
zbtb25
zinc finger and BTB domain containing 25
chr18_-_33979693 0.18 ENSDART00000021215
si:ch211-203b20.7
si:ch211-203b20.7
chr6_-_44044385 0.18 ENSDART00000075497
rybpb
RING1 and YY1 binding protein b
chr4_+_12612145 0.18 ENSDART00000181201
lmo3
LIM domain only 3
chr4_-_15420452 0.18 ENSDART00000016230
plxna4
plexin A4
chr10_-_35236949 0.18 ENSDART00000145804
ypel2a
yippee-like 2a
chr5_+_20147830 0.18 ENSDART00000098727
svopa
SV2 related protein a
chr21_+_28958471 0.18 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_+_33341640 0.17 ENSDART00000186352
pyya
peptide YYa
chr24_+_9412450 0.17 ENSDART00000132724
si:ch211-285f17.1
si:ch211-285f17.1
chr21_-_10488379 0.17 ENSDART00000163878
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr23_-_17484555 0.17 ENSDART00000187181
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr10_+_41765944 0.17 ENSDART00000171484
rnf34b
ring finger protein 34b
chr1_+_45323400 0.17 ENSDART00000148906
ENSDART00000132366
emp1
epithelial membrane protein 1
chr19_-_5103141 0.16 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr16_+_35661331 0.16 ENSDART00000161725
map7d1a
MAP7 domain containing 1a
chr16_+_54263921 0.16 ENSDART00000002856
drd2l
dopamine receptor D2 like
chr11_+_38280454 0.16 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr12_-_33579873 0.15 ENSDART00000184661
tdrkh
tudor and KH domain containing
chr21_+_34088377 0.15 ENSDART00000170070
mtmr1b
myotubularin related protein 1b
chr16_-_47483142 0.15 ENSDART00000147072
cthrc1b
collagen triple helix repeat containing 1b
chr19_-_19556778 0.15 ENSDART00000164060
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr2_+_41526904 0.15 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr18_+_34478959 0.15 ENSDART00000059394
kcnab1a
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr15_-_2184638 0.15 ENSDART00000135460
shox2
short stature homeobox 2
chr11_+_33818179 0.14 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr16_-_16120941 0.14 ENSDART00000131227
ankib1b
ankyrin repeat and IBR domain containing 1b
chr1_-_44704261 0.14 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr16_+_23087326 0.14 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr16_-_13623659 0.14 ENSDART00000168978
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr13_+_2625150 0.14 ENSDART00000164177
plpp4
phospholipid phosphatase 4
chr17_-_19963718 0.14 ENSDART00000154251
chrm3a
cholinergic receptor, muscarinic 3a
chr19_-_205104 0.14 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr17_-_14700889 0.14 ENSDART00000179975
ptp4a2a
protein tyrosine phosphatase type IVA, member 2a
chr21_-_5856050 0.13 ENSDART00000115367
CABZ01071020.1

chr5_-_30481263 0.13 ENSDART00000086734
phldb1a
pleckstrin homology-like domain, family B, member 1a
chr11_+_30244356 0.13 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr15_-_20024205 0.12 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr10_+_43039947 0.12 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr20_-_22476255 0.12 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr7_-_48263516 0.12 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
rbpms2b
RNA binding protein with multiple splicing 2b
chr21_-_15046065 0.11 ENSDART00000178507
mmp17a
matrix metallopeptidase 17a
chr19_-_38830582 0.11 ENSDART00000189966
ENSDART00000183055
adgrb2
adhesion G protein-coupled receptor B2
chr20_-_10120442 0.11 ENSDART00000144970
meis2b
Meis homeobox 2b
chr21_+_34088110 0.11 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr5_-_50781623 0.11 ENSDART00000114950
zgc:194908
zgc:194908
chr12_+_33395748 0.11 ENSDART00000129458
fasn
fatty acid synthase
chr24_+_38306010 0.11 ENSDART00000143184
mybpc2b
myosin binding protein C, fast type b
chr13_+_22295905 0.11 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr18_-_43884044 0.10 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr8_-_38477817 0.10 ENSDART00000075989
inpp5l
inositol polyphosphate-5-phosphatase L
chr9_+_20557793 0.10 ENSDART00000178434
man1a2
mannosidase, alpha, class 1A, member 2
chr15_-_8665662 0.10 ENSDART00000090675
arhgap35a
Rho GTPase activating protein 35a
chr3_+_45365098 0.10 ENSDART00000052746
ENSDART00000156555
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr2_+_4146299 0.09 ENSDART00000173418
mib1
mindbomb E3 ubiquitin protein ligase 1
chr21_+_40417152 0.09 ENSDART00000171244
ssh2b
slingshot protein phosphatase 2b
chr18_-_2433011 0.09 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr4_+_16885854 0.09 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr2_+_21229909 0.09 ENSDART00000046127
vipr1a
vasoactive intestinal peptide receptor 1a
chr20_+_13783040 0.09 ENSDART00000115329
ENSDART00000152497
lpgat1
lysophosphatidylglycerol acyltransferase 1
chr2_-_38206034 0.09 ENSDART00000144518
ENSDART00000137395
acin1a
apoptotic chromatin condensation inducer 1a
chr24_-_39518599 0.09 ENSDART00000145606
ENSDART00000031486
lyrm1
LYR motif containing 1
chr3_-_37571601 0.08 ENSDART00000016407
arf2a
ADP-ribosylation factor 2a
chr6_+_36807861 0.08 ENSDART00000161708
si:ch73-29l19.1
si:ch73-29l19.1
chr1_-_22512063 0.08 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr6_-_40922971 0.08 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr2_+_20793982 0.08 ENSDART00000014785
prg4a
proteoglycan 4a
chr7_-_12464412 0.08 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr1_+_8534698 0.08 ENSDART00000021504
smcr8b
Smith-Magenis syndrome chromosome region, candidate 8b
chr15_+_36309070 0.08 ENSDART00000157034
gmnc
geminin coiled-coil domain containing
chr9_-_51436377 0.08 ENSDART00000006612
tbr1b
T-box, brain, 1b
chr15_-_34408777 0.08 ENSDART00000139934
agmo
alkylglycerol monooxygenase
chr18_+_1837668 0.08 ENSDART00000164210
CABZ01079192.1

chr2_+_38147761 0.07 ENSDART00000135307
sall2
spalt-like transcription factor 2
chr2_+_4146606 0.07 ENSDART00000171170
mib1
mindbomb E3 ubiquitin protein ligase 1
chr2_-_23004286 0.07 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr25_+_26798673 0.07 ENSDART00000157235
ca12
carbonic anhydrase XII
chr10_-_24689280 0.07 ENSDART00000191476
si:ch211-287a12.9
si:ch211-287a12.9
chr15_-_25518084 0.07 ENSDART00000158594
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr21_-_11654422 0.06 ENSDART00000081614
ENSDART00000132699
cast
calpastatin
chr22_+_16308450 0.06 ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr15_+_40792667 0.06 ENSDART00000193186
ENSDART00000184559
fat3a
FAT atypical cadherin 3a
chr23_+_33963619 0.06 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr17_+_28628404 0.06 ENSDART00000032975
ENSDART00000143607
heatr5a
HEAT repeat containing 5a
chr4_+_12612723 0.06 ENSDART00000133767
lmo3
LIM domain only 3
chr21_+_30355767 0.06 ENSDART00000189948
CR749164.1

chr23_+_20518504 0.06 ENSDART00000114246
adnpb
activity-dependent neuroprotector homeobox b
chr8_+_28452738 0.06 ENSDART00000062706
tmem189
transmembrane protein 189
chr15_-_38154616 0.06 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr8_-_39822917 0.06 ENSDART00000067843
zgc:162025
zgc:162025
chr2_-_7246848 0.05 ENSDART00000146434
zgc:153115
zgc:153115
chr1_-_54765262 0.05 ENSDART00000150362
si:ch211-197k17.3
si:ch211-197k17.3
chr8_+_50953776 0.05 ENSDART00000013870
zgc:56596
zgc:56596
chr16_+_28578352 0.05 ENSDART00000149306
nmt2
N-myristoyltransferase 2
chr1_-_21723329 0.05 ENSDART00000137138
si:ch211-134c9.2
si:ch211-134c9.2

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.7 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.6 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.8 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.4 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.4 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 0.4 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.1 0.3 GO:0007624 ultradian rhythm(GO:0007624)
0.1 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.2 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.3 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.4 GO:0051481 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.1 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.3 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.7 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0097065 anterior head development(GO:0097065)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:0030814 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.0 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.3 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.8 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.9 GO:1990246 uniplex complex(GO:1990246)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0097189 apoptotic body(GO:0097189)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.1 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.5 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.4 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG