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PRJNA207719: Tissue specific transcriptome profiling

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Results for dlx5a

Z-value: 0.96

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Transcription factors associated with dlx5a

Gene Symbol Gene ID Gene Info
dlx5a
ENSDARG00000042296 distal-less homeobox 5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx5adr11_v1_chr19_-_41472228_414722280.286.4e-01Click!

Activity profile of dlx5a motif

Sorted Z-values of dlx5a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_6751405 0.71 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr23_+_40460333 0.61 ENSDART00000184658
soga3b
SOGA family member 3b
chr2_+_6253246 0.54 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr21_+_6751760 0.53 ENSDART00000135914
olfm1b
olfactomedin 1b
chr7_+_69019851 0.51 ENSDART00000162891
CABZ01057488.1

chr2_-_33645411 0.40 ENSDART00000114663
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr7_+_29955368 0.40 ENSDART00000173686
tpma
alpha-tropomyosin
chr17_+_43867889 0.39 ENSDART00000132673
ENSDART00000167214
zgc:66313
zgc:66313
chr6_-_6487876 0.38 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr17_+_43863708 0.36 ENSDART00000133874
ENSDART00000140316
ENSDART00000142929
ENSDART00000148090
zgc:66313
zgc:66313
chr10_+_19596214 0.34 ENSDART00000183110
CABZ01059626.1

chr15_-_44512461 0.31 ENSDART00000155456
gria4a
glutamate receptor, ionotropic, AMPA 4a
chr3_-_46817499 0.30 ENSDART00000013717
elavl3
ELAV like neuron-specific RNA binding protein 3
chr3_+_26019426 0.28 ENSDART00000135389
ENSDART00000182411
foxred2
FAD-dependent oxidoreductase domain containing 2
chr11_+_23760470 0.28 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
nfasca
neurofascin homolog (chicken) a
chr2_-_17694504 0.27 ENSDART00000133709
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr6_+_3680651 0.26 ENSDART00000013588
klhl41b
kelch-like family member 41b
chr11_+_30057762 0.26 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr11_-_44801968 0.24 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr20_-_47188966 0.24 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr15_+_15856178 0.23 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr2_+_11205795 0.22 ENSDART00000019078
lhx8a
LIM homeobox 8a
chr19_+_5480327 0.22 ENSDART00000148794
jupb
junction plakoglobin b
chr3_+_17537352 0.20 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr10_-_35149513 0.19 ENSDART00000063434
ENSDART00000131291
ripk4
receptor-interacting serine-threonine kinase 4
chr16_+_45425181 0.18 ENSDART00000168591
phf1
PHD finger protein 1
chr8_-_50888806 0.17 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr11_-_6188413 0.16 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr12_+_1469090 0.15 ENSDART00000183637
usp22
ubiquitin specific peptidase 22
chr2_-_2451181 0.15 ENSDART00000101033
pth1ra
parathyroid hormone 1 receptor a
chr17_+_49500820 0.14 ENSDART00000170306
AREL1
apoptosis resistant E3 ubiquitin protein ligase 1
chr16_+_45424907 0.14 ENSDART00000134471
phf1
PHD finger protein 1
chr2_-_21819421 0.13 ENSDART00000121586
chd7
chromodomain helicase DNA binding protein 7
chr24_-_31843173 0.12 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr16_+_35661331 0.12 ENSDART00000161725
map7d1a
MAP7 domain containing 1a
chr16_-_35329803 0.12 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr16_+_54263921 0.12 ENSDART00000002856
drd2l
dopamine receptor D2 like
chr11_+_31864921 0.11 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr5_+_66433287 0.10 ENSDART00000170757
kntc1
kinetochore associated 1
chr23_+_31912882 0.10 ENSDART00000140505
armc1l
armadillo repeat containing 1, like
chr7_-_69647988 0.10 ENSDART00000169943
LO018231.1

chr16_-_42056137 0.10 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr24_+_7336411 0.10 ENSDART00000191170
kmt2ca
lysine (K)-specific methyltransferase 2Ca
chr23_+_33963619 0.09 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr15_+_29140126 0.09 ENSDART00000060034
zgc:113149
zgc:113149
chr10_+_2529037 0.08 ENSDART00000123467
zmp:0000001301
zmp:0000001301
chr23_+_31913292 0.08 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr20_+_39457598 0.08 ENSDART00000140931
ENSDART00000156176
pimr128
Pim proto-oncogene, serine/threonine kinase, related 128
chr10_-_40968095 0.08 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr23_-_31913231 0.08 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr5_-_27867657 0.08 ENSDART00000112495
tcima
transcriptional and immune response regulator a
chr25_-_34632050 0.08 ENSDART00000170671
megf8
multiple EGF-like-domains 8
chr7_-_12464412 0.08 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr4_-_71153608 0.08 ENSDART00000190144
ENSDART00000158406
si:dkey-193i10.4
si:dkey-193i10.4
chr15_+_1796313 0.08 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr13_-_31435137 0.07 ENSDART00000057441
rtn1a
reticulon 1a
chr5_-_30620625 0.07 ENSDART00000098273
tcnl
transcobalamin like
chr4_-_5795309 0.07 ENSDART00000039987
pgm3
phosphoglucomutase 3
chr16_+_35661771 0.07 ENSDART00000161393
map7d1a
MAP7 domain containing 1a
chr6_-_40922971 0.06 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr13_+_24829996 0.06 ENSDART00000147194
si:ch211-223p8.8
si:ch211-223p8.8
chr4_-_32466676 0.06 ENSDART00000193347
ENSDART00000169396
ENSDART00000145784
si:dkey-16p6.1
si:dkey-16p6.1
chr13_-_33227411 0.05 ENSDART00000057386
golga5
golgin A5
chr14_-_14705750 0.05 ENSDART00000168092
ogt.1
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
chr14_+_11290828 0.05 ENSDART00000184078
rlim
ring finger protein, LIM domain interacting
chr4_-_63848305 0.05 ENSDART00000097308
BX901974.1

chr9_-_49964810 0.04 ENSDART00000167098
scn1a
sodium channel, voltage-gated, type I, alpha
chr17_-_43863700 0.04 ENSDART00000157530
ahsa1b
AHA1, activator of heat shock protein ATPase homolog 1b
chr3_-_23512285 0.04 ENSDART00000159151
BX682558.1

chr9_+_13229585 0.03 ENSDART00000154879
ENSDART00000141705
carf
calcium responsive transcription factor
chr16_+_31804590 0.03 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr18_+_28106139 0.03 ENSDART00000089615
kiaa1549lb
KIAA1549-like b
chr1_+_40199074 0.03 ENSDART00000179679
ENSDART00000136849
si:ch211-113e8.5
si:ch211-113e8.5
chr8_-_537716 0.03 ENSDART00000051777
zgc:101664
zgc:101664
chr12_-_14211293 0.03 ENSDART00000158399
avl9
AVL9 homolog (S. cerevisiase)
chr20_-_14114078 0.03 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr23_+_2906031 0.03 ENSDART00000109304
c23h20orf24
c23h20orf24 homolog (H. sapiens)
chr8_-_39822917 0.03 ENSDART00000067843
zgc:162025
zgc:162025
chr17_+_41343167 0.02 ENSDART00000156405
mocs1
molybdenum cofactor synthesis 1
chr19_+_15521997 0.02 ENSDART00000003164
ppp1r8a
protein phosphatase 1, regulatory subunit 8a
chr4_-_68868700 0.02 ENSDART00000187985
si:dkey-264f17.5
si:dkey-264f17.5
chr19_+_19512515 0.02 ENSDART00000180065
jazf1a
JAZF zinc finger 1a
chr25_-_7705487 0.02 ENSDART00000128099
prdm11
PR domain containing 11
chr19_+_20793237 0.02 ENSDART00000014774
txnl4a
thioredoxin-like 4A
chr18_+_11970987 0.02 ENSDART00000144111
si:dkeyp-2c8.3
si:dkeyp-2c8.3
chr10_-_26512742 0.01 ENSDART00000135951
si:dkey-5g14.1
si:dkey-5g14.1
chr8_-_52413032 0.00 ENSDART00000183039
CABZ01070469.1

chr4_+_9400012 0.00 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr17_+_25187226 0.00 ENSDART00000148431
cln8
CLN8, transmembrane ER and ERGIC protein
chr21_+_39948300 0.00 ENSDART00000137740
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx5a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0042755 eating behavior(GO:0042755)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.6 GO:0060046 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.3 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.3 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.0 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.1 GO:0048796 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis