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PRJNA207719: Tissue specific transcriptome profiling

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Results for dmbx1a+dmbx1b

Z-value: 0.33

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Transcription factors associated with dmbx1a+dmbx1b

Gene Symbol Gene ID Gene Info
dmbx1b
ENSDARG00000002510 diencephalon/mesencephalon homeobox 1b
dmbx1a
ENSDARG00000009922 diencephalon/mesencephalon homeobox 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dmbx1bdr11_v1_chr6_-_3573716_35737160.652.4e-01Click!
dmbx1adr11_v1_chr2_-_10188598_101885980.632.6e-01Click!

Activity profile of dmbx1a+dmbx1b motif

Sorted Z-values of dmbx1a+dmbx1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_1805421 0.28 ENSDART00000173143
lrp1aa
low density lipoprotein receptor-related protein 1Aa
chr21_-_28340977 0.19 ENSDART00000141629
nrxn2a
neurexin 2a
chr4_-_16628801 0.17 ENSDART00000040708
ENSDART00000064009
caprin2
caprin family member 2
chr15_+_36156986 0.17 ENSDART00000059791
sst1.1
somatostatin 1, tandem duplicate 1
chr13_-_14269626 0.17 ENSDART00000079176
gfra4a
GDNF family receptor alpha 4a
chr2_+_243778 0.16 ENSDART00000182262
CABZ01085887.1

chr17_-_20979077 0.15 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr10_+_24504292 0.14 ENSDART00000090059
mtus2a
microtubule associated tumor suppressor candidate 2a
chr10_+_24504464 0.13 ENSDART00000141387
mtus2a
microtubule associated tumor suppressor candidate 2a
chr1_-_45920632 0.13 ENSDART00000140890
pnpla6
patatin-like phospholipase domain containing 6
chr1_+_52560549 0.13 ENSDART00000167514
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr12_+_31729075 0.13 ENSDART00000152973
RNF157
si:dkey-49c17.3
chr12_+_31729498 0.13 ENSDART00000188546
ENSDART00000182562
ENSDART00000186147
RNF157
si:dkey-49c17.3
chr17_-_16965809 0.12 ENSDART00000153697
nrxn3a
neurexin 3a
chr25_-_19068557 0.11 ENSDART00000184780
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr17_-_21617618 0.11 ENSDART00000109031
gpr26
G protein-coupled receptor 26
chr1_-_16507812 0.10 ENSDART00000169081
mtmr7b
myotubularin related protein 7b
chr14_+_11909966 0.10 ENSDART00000171829
frmpd3
FERM and PDZ domain containing 3
chr3_+_34919810 0.10 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr6_+_22597362 0.10 ENSDART00000131242
cygb2
cytoglobin 2
chr23_-_27050083 0.10 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
zgc:66440
chr6_-_10320676 0.09 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr3_-_41995321 0.09 ENSDART00000192277
ttyh3a
tweety family member 3a
chr6_-_39653972 0.09 ENSDART00000155859
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr11_-_29082175 0.09 ENSDART00000123245
igsf21a
immunoglobin superfamily, member 21a
chr7_+_19904136 0.09 ENSDART00000173452
si:ch211-285j22.3
si:ch211-285j22.3
chr1_-_12126535 0.09 ENSDART00000164817
ENSDART00000015251
mttp
microsomal triglyceride transfer protein
chr5_-_5243079 0.09 ENSDART00000130576
ENSDART00000164377
mvb12ba
multivesicular body subunit 12Ba
chr1_+_33383644 0.08 ENSDART00000187194
dhrsx
dehydrogenase/reductase (SDR family) X-linked
chr12_+_3848109 0.08 ENSDART00000144067
ENSDART00000192042
cabp5a
calcium binding protein 5a
chr11_-_29082429 0.08 ENSDART00000041443
igsf21a
immunoglobin superfamily, member 21a
chr7_+_19903924 0.08 ENSDART00000159112
si:ch211-285j22.3
si:ch211-285j22.3
chr1_+_47585700 0.07 ENSDART00000153746
ENSDART00000084457
sh3pxd2aa
SH3 and PX domains 2Aa
chr7_+_56577906 0.07 ENSDART00000184023
hp
haptoglobin
chr17_-_8656155 0.07 ENSDART00000148990
ctbp2a
C-terminal binding protein 2a
chr13_-_31938512 0.07 ENSDART00000026726
ENSDART00000182666
diexf
digestive organ expansion factor homolog
chr7_-_72423666 0.07 ENSDART00000191214
rph3ab
rabphilin 3A homolog (mouse), b
chr20_-_9963713 0.06 ENSDART00000104234
gjd2b
gap junction protein delta 2b
chr15_-_6976851 0.06 ENSDART00000158474
ENSDART00000168943
ENSDART00000169944
si:ch73-311h14.2
si:ch73-311h14.2
chr7_+_38395197 0.06 ENSDART00000138669
cep89
centrosomal protein 89
chr23_+_45512825 0.06 ENSDART00000064846
prelid1b
PRELI domain containing 1b
chr9_+_31075896 0.06 ENSDART00000188042
clybl
citrate lyase beta like
chr3_+_15296824 0.06 ENSDART00000043801
cabp5b
calcium binding protein 5b
chr8_-_30424182 0.06 ENSDART00000099021
dock8
dedicator of cytokinesis 8
chr22_-_16412496 0.06 ENSDART00000137497
cts12
cathepsin 12
chr14_-_48939560 0.05 ENSDART00000021736
scocb
short coiled-coil protein b
chr18_-_10713230 0.05 ENSDART00000183646
rbm28
RNA binding motif protein 28
chr19_-_6239248 0.05 ENSDART00000014127
pou2f2a
POU class 2 homeobox 2a
chr18_-_10713414 0.05 ENSDART00000034817
rbm28
RNA binding motif protein 28
chr4_-_56083825 0.05 ENSDART00000157710
znf986
zinc finger protein 986
chr3_+_16762483 0.05 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr12_-_13081229 0.05 ENSDART00000152510
ENSDART00000126866
ccser2b
coiled-coil serine-rich protein 2b
chr17_+_10593398 0.05 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr10_+_31244619 0.05 ENSDART00000145562
ENSDART00000184412
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr8_+_46327350 0.05 ENSDART00000145618
si:dkey-75a21.2
si:dkey-75a21.2
chr13_+_1015749 0.05 ENSDART00000190982
prokr1b
prokineticin receptor 1b
chr11_-_3366782 0.04 ENSDART00000127982
suox
sulfite oxidase
chr20_-_31308805 0.04 ENSDART00000147045
hpcal1
hippocalcin-like 1
chr5_-_69180587 0.04 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr15_-_8191992 0.04 ENSDART00000155381
ENSDART00000190714
bach1a
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr21_-_3770636 0.04 ENSDART00000053596
scamp1
secretory carrier membrane protein 1
chr4_-_76488854 0.04 ENSDART00000132323
ftr51
finTRIM family, member 51
chr14_-_3944017 0.04 ENSDART00000055817
si:ch73-49o8.1
si:ch73-49o8.1
chr18_+_15182965 0.04 ENSDART00000137018
si:ch73-62b13.1
si:ch73-62b13.1
chr2_+_44972720 0.04 ENSDART00000075146
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr1_+_35949269 0.04 ENSDART00000180628
BX276105.3

chr17_-_31058900 0.04 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
eml1
echinoderm microtubule associated protein like 1
chr19_+_24324967 0.03 ENSDART00000090081
sema4ab
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ab
chr10_-_27199135 0.03 ENSDART00000189511
ENSDART00000180314
auts2a
autism susceptibility candidate 2a
chr10_+_6013076 0.03 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr19_-_30811161 0.03 ENSDART00000103524
myclb
MYCL proto-oncogene, bHLH transcription factor b
chr5_-_22602979 0.03 ENSDART00000146287
nono
non-POU domain containing, octamer-binding
chr10_-_18468385 0.03 ENSDART00000183302
si:dkey-28o19.1
si:dkey-28o19.1
chr20_-_1141722 0.03 ENSDART00000152675
gabrr1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr12_+_33894396 0.03 ENSDART00000130853
ENSDART00000152988
mfsd13a
major facilitator superfamily domain containing 13A
chr21_+_44773237 0.03 ENSDART00000084780
rnf121
ring finger protein 121
chr5_+_25733774 0.03 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr10_-_7988396 0.03 ENSDART00000141445
ENSDART00000024282
ewsr1a
EWS RNA-binding protein 1a
chr12_+_27213733 0.03 ENSDART00000133048
nbr1a
neighbor of brca1 gene 1a
chr16_-_46578523 0.03 ENSDART00000131061
si:dkey-152b24.6
si:dkey-152b24.6
chr8_+_23142946 0.02 ENSDART00000152933
si:ch211-196c10.13
si:ch211-196c10.13
chr1_+_47091468 0.02 ENSDART00000036783
cryzl1
crystallin, zeta (quinone reductase)-like 1
chr4_-_42039794 0.02 ENSDART00000110313
si:dkeyp-85d8.5
si:dkeyp-85d8.5
chr16_+_48678655 0.02 ENSDART00000150156
tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_+_32142382 0.02 ENSDART00000133035
syt5a
synaptotagmin Va
chr23_-_545942 0.02 ENSDART00000105316
samhd1
SAM domain and HD domain 1
chr15_-_8191841 0.02 ENSDART00000156663
bach1a
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr17_+_17955063 0.02 ENSDART00000104999
ccdc85ca
coiled-coil domain containing 85C, a
chr22_+_2709467 0.02 ENSDART00000141416
znf1171
zinc finger protein 1171
chr16_+_16265850 0.02 ENSDART00000181265
setd2
SET domain containing 2
chr5_-_69180227 0.02 ENSDART00000154816
zgc:171967
zgc:171967
chr12_+_33460794 0.02 ENSDART00000007053
ENSDART00000142716
narf
nuclear prelamin A recognition factor
chr5_+_69808763 0.02 ENSDART00000143482
fsd1l
fibronectin type III and SPRY domain containing 1-like
chr2_-_38363017 0.01 ENSDART00000088026
prmt5
protein arginine methyltransferase 5
chr12_+_33894665 0.01 ENSDART00000004769
mfsd13a
major facilitator superfamily domain containing 13A
chr7_+_65121743 0.01 ENSDART00000108471
ipo7
importin 7
chr9_-_9689367 0.01 ENSDART00000191820
gpr156
G protein-coupled receptor 156
chr18_+_15644559 0.01 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr13_+_50151407 0.01 ENSDART00000031858
gpr137ba
G protein-coupled receptor 137Ba
chr12_+_292452 0.01 ENSDART00000189944
CABZ01058222.1

chr15_-_7337148 0.01 ENSDART00000182568
SLC7A1 (1 of many)
high affinity cationic amino acid transporter 1
chr5_-_22602780 0.01 ENSDART00000011699
nono
non-POU domain containing, octamer-binding
chr15_+_45640906 0.00 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr3_+_19914332 0.00 ENSDART00000078982
vat1
vesicle amine transport 1
chr16_-_12236362 0.00 ENSDART00000114759
lpcat3
lysophosphatidylcholine acyltransferase 3
chr15_-_41734639 0.00 ENSDART00000154230
ENSDART00000167443
ftr90
finTRIM family, member 90
chr23_-_1065435 0.00 ENSDART00000138150
si:ch1073-272j17.3
si:ch1073-272j17.3
chr13_+_1726953 0.00 ENSDART00000103004
zmp:0000000760
zmp:0000000760
chr5_-_38107741 0.00 ENSDART00000156853
si:ch211-284e13.14
si:ch211-284e13.14
chr4_+_10721795 0.00 ENSDART00000136000
ENSDART00000067253
stab2
stabilin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of dmbx1a+dmbx1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.0 0.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:1902590 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0 0.0 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.0 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.0 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.1 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.0 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)