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PRJNA207719: Tissue specific transcriptome profiling

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Results for e2f8

Z-value: 0.93

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Transcription factors associated with e2f8

Gene Symbol Gene ID Gene Info
e2f8
ENSDARG00000057323 E2F transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
e2f8dr11_v1_chr7_-_16597130_165971300.187.7e-01Click!

Activity profile of e2f8 motif

Sorted Z-values of e2f8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_14155781 0.69 ENSDART00000169232
nr0b2b
nuclear receptor subfamily 0, group B, member 2b
chr14_+_46223458 0.60 ENSDART00000173428
cabp2b
calcium binding protein 2b
chr24_-_2829049 0.56 ENSDART00000164913
PPP1R3G
si:ch211-152c8.5
chr4_-_2380173 0.55 ENSDART00000177727
nap1l1
nucleosome assembly protein 1-like 1
chr7_+_24814866 0.54 ENSDART00000173581
si:ch211-226l4.6
si:ch211-226l4.6
chr9_+_33220342 0.50 ENSDART00000100893
ENSDART00000113451
si:ch211-125e6.13
si:ch211-125e6.13
chr11_-_29685853 0.45 ENSDART00000128468
nr0b1
nuclear receptor subfamily 0, group B, member 1
chr6_-_40071899 0.44 ENSDART00000034730
sec61a1
Sec61 translocon alpha 1 subunit
chr3_-_5016893 0.37 ENSDART00000165968
CSDC2 (1 of many)
cold shock domain containing C2
chr6_+_50451337 0.36 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr16_-_4640539 0.36 ENSDART00000076955
ENSDART00000131949
cyp4t8
cytochrome P450, family 4, subfamily T, polypeptide 8
chr2_+_5793908 0.35 ENSDART00000145219
slc35d1b
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1b
chr3_-_49514874 0.34 ENSDART00000167179
asf1ba
anti-silencing function 1Ba histone chaperone
chr7_-_55648336 0.33 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
pabpn1l
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr1_-_18811517 0.32 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr6_-_33916756 0.32 ENSDART00000137447
ENSDART00000138488
nasp
nuclear autoantigenic sperm protein (histone-binding)
chr12_+_31616412 0.32 ENSDART00000124439
cpn1
carboxypeptidase N, polypeptide 1
chr11_-_26576754 0.32 ENSDART00000191733
ENSDART00000002846
st3gal8
ST3 beta-galactoside alpha-2,3-sialyltransferase 8
chr2_+_32016256 0.30 ENSDART00000005143
mycb
MYC proto-oncogene, bHLH transcription factor b
chr7_+_69905307 0.30 ENSDART00000035907
sec24d
SEC24 homolog D, COPII coat complex component
chr13_+_46941930 0.29 ENSDART00000056962
fbxo5
F-box protein 5
chr21_-_11970199 0.27 ENSDART00000114524
nop56
NOP56 ribonucleoprotein homolog
chr20_-_38827623 0.27 ENSDART00000153310
cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr17_-_36529016 0.27 ENSDART00000025019
colec11
collectin sub-family member 11
chr2_+_32016516 0.27 ENSDART00000135040
mycb
MYC proto-oncogene, bHLH transcription factor b
chr3_+_25999477 0.26 ENSDART00000024316
mcm5
minichromosome maintenance complex component 5
chr19_+_32603627 0.26 ENSDART00000052086
tmem54b
transmembrane protein 54b
chr23_+_20803270 0.25 ENSDART00000097381
zgc:154075
zgc:154075
chr5_-_37959874 0.23 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr3_-_35865040 0.23 ENSDART00000102952
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr20_+_13141408 0.23 ENSDART00000034098
dtl
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr17_-_36529449 0.22 ENSDART00000187252
colec11
collectin sub-family member 11
chr14_-_28566238 0.21 ENSDART00000172547
insb
preproinsulin b
chr9_-_2892045 0.21 ENSDART00000137201
cdca7a
cell division cycle associated 7a
chr18_-_34171280 0.21 ENSDART00000122321
slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr3_+_43086548 0.21 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr4_-_7869731 0.20 ENSDART00000067339
mcm10
minichromosome maintenance 10 replication initiation factor
chr6_-_18531760 0.20 ENSDART00000167167
utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr23_+_44049509 0.19 ENSDART00000102003
txk
TXK tyrosine kinase
chr18_-_34170918 0.18 ENSDART00000015079
slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr18_+_38321039 0.18 ENSDART00000132534
ENSDART00000111260
ENSDART00000192806
alx4b
ALX homeobox 4b
chr19_-_44064842 0.18 ENSDART00000151541
mterf3
mitochondrial transcription termination factor 3
chr10_+_6884123 0.17 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr15_-_36055401 0.17 ENSDART00000154476
col4a4
collagen, type IV, alpha 4
chr24_-_35561672 0.17 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr7_+_71535045 0.17 ENSDART00000047069
tyms
thymidylate synthetase
chr9_-_2892250 0.16 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr13_+_48359573 0.15 ENSDART00000161959
ENSDART00000165311
msh6
mutS homolog 6 (E. coli)
chr13_+_2894536 0.15 ENSDART00000183678
CABZ01087629.1

chr8_+_52415603 0.15 ENSDART00000021604
ENSDART00000191424
gins4
GINS complex subunit 4 (Sld5 homolog)
chr11_-_4302251 0.15 ENSDART00000182554
CT033790.1

chr1_+_59142783 0.15 ENSDART00000152669
gpr108
G protein-coupled receptor 108
chr7_-_73845736 0.15 ENSDART00000193414
zgc:173552
zgc:173552
chr14_-_32631519 0.15 ENSDART00000167282
ENSDART00000052938
atp11c
ATPase phospholipid transporting 11C
chr7_+_26545911 0.14 ENSDART00000135313
tnk1
tyrosine kinase, non-receptor, 1
chr13_-_47403154 0.14 ENSDART00000114318
bcl2l11
BCL2 like 11
chr6_+_21062416 0.14 ENSDART00000141643
si:dkey-91f15.1
si:dkey-91f15.1
chr18_+_33788340 0.14 ENSDART00000136950
si:dkey-145c18.2
si:dkey-145c18.2
chr23_+_42434348 0.14 ENSDART00000161027
cyp2aa1
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr25_-_35140746 0.13 ENSDART00000129969
si:ch211-113a14.19
si:ch211-113a14.19
chr18_+_35842933 0.13 ENSDART00000151587
ENSDART00000131121
ppp1r13l
protein phosphatase 1, regulatory subunit 13 like
chr22_-_22301672 0.13 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr16_+_33953644 0.13 ENSDART00000164447
ENSDART00000159969
arid1aa
AT rich interactive domain 1Aa (SWI-like)
chr8_-_44238526 0.13 ENSDART00000061115
ENSDART00000132473
ENSDART00000138019
ENSDART00000133021
piwil1
piwi-like RNA-mediated gene silencing 1
chr8_+_41038141 0.13 ENSDART00000075620
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr11_-_11792766 0.13 ENSDART00000011657
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr5_+_22459087 0.12 ENSDART00000134781
BX546499.1

chr2_-_6104035 0.12 ENSDART00000053867
zte38
zebrafish testis-expressed 38
chr25_-_35110695 0.12 ENSDART00000099859
hist1h2a10
histone cluster 1 H2A family member 10
chr7_+_5956937 0.12 ENSDART00000170763
hist1h2a4
histone cluster 1 H2A family member 4
chr10_+_10386435 0.12 ENSDART00000179214
ENSDART00000189799
ENSDART00000193875
sardh
sarcosine dehydrogenase
chr25_-_35145920 0.12 ENSDART00000157137
si:dkey-261m9.19
si:dkey-261m9.19
chr16_+_53278406 0.12 ENSDART00000010792
ptdss1a
phosphatidylserine synthase 1a
chr1_-_46505310 0.12 ENSDART00000178072
si:busm1-105l16.2
si:busm1-105l16.2
chr7_-_73854476 0.12 ENSDART00000186481
zgc:173552
zgc:173552
chr24_-_13349802 0.11 ENSDART00000164729
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr10_-_37487612 0.11 ENSDART00000167964
ENSDART00000171326
si:dkey-65j4.2
si:dkey-65j4.2
chr25_+_25464630 0.11 ENSDART00000150537
rassf7a
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr20_+_2732992 0.11 ENSDART00000152697
syncrip
synaptotagmin binding, cytoplasmic RNA interacting protein
chr3_-_14571514 0.11 ENSDART00000137197
swsap1
SWIM-type zinc finger 7 associated protein 1
chr22_-_38274188 0.11 ENSDART00000139420
ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr13_+_8255106 0.11 ENSDART00000080465
hells
helicase, lymphoid specific
chr25_+_35133404 0.11 ENSDART00000188505
hist1h2a2
histone cluster 1 H2A family member 2
chr19_-_2582858 0.11 ENSDART00000113829
cdca7b
cell division cycle associated 7b
chr7_+_26545502 0.11 ENSDART00000140528
tnk1
tyrosine kinase, non-receptor, 1
chr10_+_26646104 0.11 ENSDART00000187685
adgrg4b
adhesion G protein-coupled receptor G4b
chr4_+_74943111 0.11 ENSDART00000004739
nup50
nucleoporin 50
chr23_+_39558508 0.11 ENSDART00000017902
camk1gb
calcium/calmodulin-dependent protein kinase IGb
chr5_+_67390645 0.11 ENSDART00000014822
ebf2
early B cell factor 2
chr20_+_53368611 0.10 ENSDART00000060432
cdc40
cell division cycle 40 homolog (S. cerevisiae)
chr21_+_11244068 0.10 ENSDART00000163432
arid6
AT-rich interaction domain 6
chr2_+_7818368 0.10 ENSDART00000007068
kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr24_-_13349464 0.10 ENSDART00000134482
ENSDART00000139212
terf1
telomeric repeat binding factor (NIMA-interacting) 1
chr15_+_14202114 0.10 ENSDART00000169369
si:dkey-243k1.3
si:dkey-243k1.3
chr1_-_34450622 0.10 ENSDART00000083736
lmo7b
LIM domain 7b
chr7_-_6355459 0.10 ENSDART00000172898
CU457819.1

chr25_-_35109536 0.10 ENSDART00000185229
CU302436.5

chr9_-_48407408 0.10 ENSDART00000058248
zgc:172182
zgc:172182
chr19_+_42660158 0.10 ENSDART00000018328
fbxl2
F-box and leucine-rich repeat protein 2
chr4_-_74062634 0.10 ENSDART00000105992
si:cabz01069012.2
si:cabz01069012.2
chr1_-_58505626 0.10 ENSDART00000171304
si:ch73-236c18.8
si:ch73-236c18.8
chr12_+_18234557 0.10 ENSDART00000130741
fam20cb
family with sequence similarity 20, member Cb
chr7_-_6345507 0.10 ENSDART00000173032
CU457819.4
Histone H3.2
chr7_+_29509255 0.10 ENSDART00000076172
si:dkey-182o15.5
si:dkey-182o15.5
chr23_-_29357764 0.10 ENSDART00000156512
si:ch211-129o18.4
si:ch211-129o18.4
chr8_-_12403077 0.09 ENSDART00000142150
phf19
PHD finger protein 19
chr4_-_16644708 0.09 ENSDART00000042307
sinhcaf
SIN3-HDAC complex associated factor
chr17_+_2727807 0.09 ENSDART00000178759
kcnk10b
potassium channel, subfamily K, member 10b
chr19_-_30359059 0.09 ENSDART00000103471
khdrbs1b
KH domain containing, RNA binding, signal transduction associated 1b
chr9_-_49964810 0.09 ENSDART00000167098
scn1a
sodium channel, voltage-gated, type I, alpha
chr7_-_64152087 0.09 ENSDART00000165234
CR354398.1

chr4_-_74069252 0.09 ENSDART00000112802
si:cabz01069012.2
si:cabz01069012.2
chr25_+_32525131 0.09 ENSDART00000156145
scaper
S-phase cyclin A-associated protein in the ER
chr8_+_45186989 0.09 ENSDART00000143861
si:ch211-220m6.4
si:ch211-220m6.4
chr7_-_804515 0.09 ENSDART00000159359
rela
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr22_-_4439311 0.09 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr7_-_6362460 0.09 ENSDART00000129239
hist1h2a4
histone cluster 1 H2A family member 4
chr5_-_30382925 0.08 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr15_-_4596623 0.08 ENSDART00000132227
eif4h
eukaryotic translation initiation factor 4h
chr7_+_66565572 0.08 ENSDART00000180250
tmem176l.3b
transmembrane protein 176l.3b
chr15_+_5628363 0.08 ENSDART00000148193
mrap
melanocortin 2 receptor accessory protein
chr22_+_8753365 0.08 ENSDART00000106086
si:dkey-182g1.2
si:dkey-182g1.2
chr2_-_57378748 0.08 ENSDART00000149235
tcf3a
transcription factor 3a
chr10_+_573667 0.08 ENSDART00000110384
smad4a
SMAD family member 4a
chr4_-_8014463 0.08 ENSDART00000036153
ccdc3a
coiled-coil domain containing 3a
chr24_+_26432541 0.08 ENSDART00000105784
ENSDART00000122554
cldn11b
claudin 11b
chr7_-_6415991 0.08 ENSDART00000173349
CU457819.3
Histone H3.2
chr2_+_35728033 0.07 ENSDART00000002094
ankrd45
ankyrin repeat domain 45
chr13_-_45942000 0.07 ENSDART00000158534
ENSDART00000171822
ENSDART00000166442
si:ch211-62a1.4
si:ch211-62a1.4
chr15_-_17618800 0.07 ENSDART00000157185
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr20_+_18703454 0.07 ENSDART00000152342
eif5
eukaryotic translation initiation factor 5
chr4_-_7231480 0.07 ENSDART00000159436
si:ch211-170p16.1
si:ch211-170p16.1
chr3_+_14571813 0.07 ENSDART00000146728
ENSDART00000171731
znf653
zinc finger protein 653
chr2_-_53500424 0.07 ENSDART00000037557
admp
anti-dorsalizing morphogenic protein
chr3_+_8826905 0.07 ENSDART00000167474
ENSDART00000168088
si:dkeyp-30d6.2
si:dkeyp-30d6.2
chr6_-_28345002 0.07 ENSDART00000158955
si:busm1-105l16.2
si:busm1-105l16.2
chr13_-_18011168 0.07 ENSDART00000144813
march8
membrane-associated ring finger (C3HC4) 8
chr2_+_48074243 0.07 ENSDART00000056291
klf6b
Kruppel-like factor 6b
chr6_+_38896158 0.07 ENSDART00000029930
ENSDART00000131347
slc48a1b
solute carrier family 48 (heme transporter), member 1b
chr4_-_58978527 0.07 ENSDART00000150408
si:ch211-64i20.5_2
si:ch211-64i20.5_2
chr4_-_73488406 0.07 ENSDART00000115002
si:ch73-266f23.1
si:ch73-266f23.1
chr22_+_18349794 0.06 ENSDART00000186580
gatad2ab
GATA zinc finger domain containing 2Ab
chr22_-_6959769 0.06 ENSDART00000105866
si:ch73-213k20.5
si:ch73-213k20.5
chr3_-_53092509 0.06 ENSDART00000062081
lpar2a
lysophosphatidic acid receptor 2a
chr18_+_19972853 0.06 ENSDART00000180071
skor1b
SKI family transcriptional corepressor 1b
chr11_+_45092866 0.06 ENSDART00000163408
si:dkey-93h22.8
si:dkey-93h22.8
chr25_-_35102781 0.06 ENSDART00000180881
ENSDART00000153747
si:dkey-108k21.24
si:dkey-108k21.24
chr8_-_44363596 0.06 ENSDART00000123658
si:busm1-228j01.4
si:busm1-228j01.4
chr7_+_34453185 0.06 ENSDART00000173875
ENSDART00000173921
ENSDART00000173995
si:cabz01009626.1
si:cabz01009626.1
chr23_+_29358188 0.06 ENSDART00000189242
tardbpl
TAR DNA binding protein, like
chr6_-_43817761 0.06 ENSDART00000183945
foxp1b
forkhead box P1b
chr12_-_30345444 0.06 ENSDART00000152985
vwa2
von Willebrand factor A domain containing 2
chr2_+_17055069 0.06 ENSDART00000115078
thpo
thrombopoietin
chr7_+_41812190 0.05 ENSDART00000113732
ENSDART00000174137
orc6
origin recognition complex, subunit 6
chr15_-_44637492 0.05 ENSDART00000170936
alp3
alkaline phosphatase 3
chr18_+_27571448 0.05 ENSDART00000147886
cd82b
CD82 molecule b
chr13_+_48358467 0.05 ENSDART00000171080
ENSDART00000162531
msh6
mutS homolog 6 (E. coli)
chr1_+_6243906 0.05 ENSDART00000127329
gtf3c3
general transcription factor IIIC, polypeptide 3
chr7_+_66565930 0.05 ENSDART00000154597
tmem176l.3b
transmembrane protein 176l.3b
chr1_+_38858399 0.05 ENSDART00000165454
CU915762.1

chr7_+_41812817 0.05 ENSDART00000174165
orc6
origin recognition complex, subunit 6
chr24_-_30843250 0.05 ENSDART00000162920
ptbp2a
polypyrimidine tract binding protein 2a
chr4_-_64123545 0.05 ENSDART00000170040
BX914205.2

chr22_+_25590391 0.05 ENSDART00000178133
aars2
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr8_+_8196087 0.04 ENSDART00000026965
plxnb3
plexin B3
chr23_-_16981899 0.04 ENSDART00000125472
ENSDART00000142297
ENSDART00000143180
dnmt3bb.3
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr11_+_24290130 0.04 ENSDART00000029695
pnp4a
purine nucleoside phosphorylase 4a
chr16_+_29558530 0.04 ENSDART00000088146
ensab
endosulfine alpha b
chr21_-_2360906 0.04 ENSDART00000171645
si:ch73-299h12.9
si:ch73-299h12.9
chr15_-_17619306 0.04 ENSDART00000184011
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr11_-_18107447 0.04 ENSDART00000187376
qrich1
glutamine-rich 1
chr19_+_40069524 0.04 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr7_+_41812636 0.04 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr11_-_18017918 0.03 ENSDART00000040171
qrich1
glutamine-rich 1
chr7_-_23971497 0.03 ENSDART00000173603
si:dkey-183c6.8
si:dkey-183c6.8
chr22_+_8753092 0.03 ENSDART00000140720
si:dkey-182g1.2
si:dkey-182g1.2
chr19_-_32042105 0.03 ENSDART00000088358
znf704
zinc finger protein 704
chr19_-_340641 0.03 ENSDART00000183848
golph3l
golgi phosphoprotein 3-like
chr7_+_1550966 0.03 ENSDART00000177863
ENSDART00000126840
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr2_+_9755422 0.03 ENSDART00000018524
pcyt1aa
phosphate cytidylyltransferase 1, choline, alpha a
chr15_+_618081 0.03 ENSDART00000181518
si:ch211-210b2.1
si:ch211-210b2.1
chr3_+_5504990 0.03 ENSDART00000143626
si:ch73-264i18.2
si:ch73-264i18.2
chr23_+_10805188 0.03 ENSDART00000035693
ppp4r2a
protein phosphatase 4, regulatory subunit 2a
chr2_+_37424261 0.03 ENSDART00000132427
phc3
polyhomeotic homolog 3 (Drosophila)
chr23_+_29357790 0.03 ENSDART00000139223
ENSDART00000141928
tardbpl
TAR DNA binding protein, like
chr1_-_28890028 0.03 ENSDART00000075500
poglut1
protein O-glucosyltransferase 1
chr16_-_9453591 0.02 ENSDART00000126154
prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr2_-_54946834 0.02 ENSDART00000192280
CABZ01086574.1

chr2_-_20599315 0.02 ENSDART00000114199
si:ch211-267e7.3
si:ch211-267e7.3
chr2_-_45027754 0.02 ENSDART00000168469
vwa5b2
von Willebrand factor A domain containing 5B2
chr23_-_30045661 0.02 ENSDART00000122239
ENSDART00000103480
ccdc187
coiled-coil domain containing 187
chr6_-_8466717 0.02 ENSDART00000151577
ENSDART00000151800
ENSDART00000151227
si:dkey-217d24.6
si:dkey-217d24.6
chr7_+_57725708 0.02 ENSDART00000056466
ENSDART00000142259
ENSDART00000166198
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr1_+_9144958 0.02 ENSDART00000046507
rasd3
RASD family member 3
chr19_-_340347 0.02 ENSDART00000139924
golph3l
golgi phosphoprotein 3-like
chr7_-_39360325 0.02 ENSDART00000098033
ENSDART00000173695
ENSDART00000173466
ENSDART00000173734
ambra1a
autophagy/beclin-1 regulator 1a
chr1_+_27052530 0.02 ENSDART00000184065
bnc2
basonuclin 2
chr5_-_19394440 0.02 ENSDART00000163771
foxn4
forkhead box N4
chr23_+_21482571 0.02 ENSDART00000187368
si:dkey-1c11.1
si:dkey-1c11.1
chr25_-_17579701 0.01 ENSDART00000073684
mmp15a
matrix metallopeptidase 15a

Network of associatons between targets according to the STRING database.

First level regulatory network of e2f8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.5 GO:0008584 male gonad development(GO:0008584)
0.1 0.3 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.1 0.3 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.4 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052)
0.0 0.5 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.4 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.7 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.0 0.1 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0009217 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.4 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0008406 gonad development(GO:0008406)
0.0 0.2 GO:0008156 negative regulation of DNA replication(GO:0008156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.4 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0035060 brahma complex(GO:0035060)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042806 fucose binding(GO:0042806)
0.1 0.3 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.4 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0032138 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway