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PRJNA207719: Tissue specific transcriptome profiling

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Results for e4f1+si:dkeyp-79b7.12

Z-value: 1.11

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Transcription factors associated with e4f1+si:dkeyp-79b7.12

Gene Symbol Gene ID Gene Info
ENSDARG00000038243 E4F transcription factor 1
ENSDARG00000105305 si_dkeyp-79b7.12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
e4f1dr11_v1_chr3_-_18737126_187371260.829.1e-02Click!
si:dkeyp-79b7.12dr11_v1_chr22_+_2207502_22075020.454.4e-01Click!

Activity profile of e4f1+si:dkeyp-79b7.12 motif

Sorted Z-values of e4f1+si:dkeyp-79b7.12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_7632187 1.25 ENSDART00000041714
ATPase H+ transporting V0 subunit a1b
chr15_-_163586 1.22 ENSDART00000163597
septin-4
chr2_-_42415902 1.10 ENSDART00000142489
solute carrier organic anion transporter family member 5A1b
chr23_-_35694461 1.10 ENSDART00000185884
tubulin, alpha 1c
chr9_+_21722733 1.04 ENSDART00000102021
SRY (sex determining region Y)-box 1a
chr23_-_35694171 1.03 ENSDART00000077539
tubulin, alpha 1c
chr23_-_29668286 0.95 ENSDART00000129248
calsyntenin 1
chr4_+_9669717 0.94 ENSDART00000004604
si:dkey-153k10.9
chr20_+_29743904 0.85 ENSDART00000146366
ENSDART00000153154
kinase D-interacting substrate 220b
chr1_-_51606552 0.85 ENSDART00000130828
cannabinoid receptor interacting protein 1a
chr16_-_32649929 0.83 ENSDART00000136161
failed axon connections homolog b
chr6_-_48311 0.78 ENSDART00000131010
zgc:114175
chr7_+_29133321 0.68 ENSDART00000052346
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr10_+_6496185 0.67 ENSDART00000164770
receptor accessory protein 5
chr13_+_35856463 0.66 ENSDART00000171056
ENSDART00000017202
potassium channel, subfamily K, member 1b
chr10_+_44903676 0.64 ENSDART00000158553
zgc:114173
chr17_+_8184649 0.63 ENSDART00000091818
tubby like protein 4b
chr21_-_45613564 0.61 ENSDART00000160324

chr9_-_54840124 0.59 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr16_+_32995882 0.58 ENSDART00000170157
protease, serine, 35
chr11_+_40649412 0.57 ENSDART00000043016
ENSDART00000134560
solute carrier family 45, member 1
chr16_-_45069882 0.54 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr20_+_25911342 0.53 ENSDART00000146004
tau tubulin kinase 2b
chr9_+_219124 0.53 ENSDART00000161484
mitogen-activated protein kinase kinase kinase 12
chr21_-_43606502 0.53 ENSDART00000151030
si:ch73-362m14.4
chr15_+_46386261 0.52 ENSDART00000191793
immunoglobulin superfamily member 11
chr22_+_33362552 0.51 ENSDART00000101580
nicolin 1
chr9_-_42418470 0.50 ENSDART00000144353
calcitonin receptor-like a
chr22_-_29922872 0.49 ENSDART00000020249
dual specificity phosphatase 5
chr13_+_23843712 0.47 ENSDART00000057611
opioid receptor, mu 1
chr20_-_37629084 0.46 ENSDART00000141734
human immunodeficiency virus type I enhancer binding protein 2a
chr8_-_9118958 0.43 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr2_+_9821757 0.42 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr20_-_44576949 0.42 ENSDART00000148639
UBX domain protein 2A
chr19_-_32888758 0.42 ENSDART00000052080
lysosomal protein transmembrane 4 beta
chr23_-_17509656 0.40 ENSDART00000148423
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr20_+_19512727 0.40 ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr25_-_23052707 0.39 ENSDART00000024633
dual specificity phosphatase 8a
chr13_+_32446169 0.39 ENSDART00000143325
5'-nucleotidase, cytosolic IB a
chr20_-_18915376 0.37 ENSDART00000063725
XK, Kell blood group complex subunit-related family, member 6b
chr11_+_4026229 0.35 ENSDART00000041417
calcium/calmodulin-dependent protein kinase Ib
chr18_-_19103929 0.35 ENSDART00000188370
ENSDART00000177621
DENN/MADD domain containing 4A
chr8_-_50346246 0.32 ENSDART00000025008
stanniocalcin 1
chr3_-_21137362 0.32 ENSDART00000104051
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr3_-_18373604 0.31 ENSDART00000148132
sperm associated antigen 9a
chr3_+_20156956 0.31 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr25_-_13659249 0.31 ENSDART00000045488
casein kinase 2, alpha prime polypeptide b
chr13_-_38792061 0.31 ENSDART00000162858
LMBR1 domain containing 1
chr16_+_25137483 0.31 ENSDART00000155666
zinc finger protein 576, tandem duplicate 1
chr3_+_36713477 0.31 ENSDART00000181105
ENSDART00000161897
ENSDART00000189952
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr14_+_790166 0.30 ENSDART00000123912
adrenergic, alpha-2D-, receptor a
chr9_-_13963078 0.30 ENSDART00000193398
ENSDART00000061156
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr23_-_27505825 0.30 ENSDART00000137229
ENSDART00000013797
ankyrin repeat and SOCS box containing 8
chr23_-_30764319 0.30 ENSDART00000075918
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr17_+_23554932 0.30 ENSDART00000135814
pantothenate kinase 1a
chr8_+_44714336 0.29 ENSDART00000145801
ELMO/CED-12 domain containing 3
chr15_+_5116179 0.29 ENSDART00000101937
phosphoglucomutase 2-like 1
chr20_+_9211237 0.28 ENSDART00000139527
si:ch211-59d15.4
chr3_-_18373425 0.28 ENSDART00000178522
sperm associated antigen 9a
chr8_-_24113575 0.28 ENSDART00000099692
ENSDART00000186211
DNA cross-link repair 1B
chr5_+_24128908 0.27 ENSDART00000029719
si:ch211-114c12.2
chr16_+_21242491 0.27 ENSDART00000145886
oxysterol binding protein-like 3b
chr23_+_31405497 0.25 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr4_-_149334 0.24 ENSDART00000163280
TANK-binding kinase 1
chr19_-_20106486 0.24 ENSDART00000043924
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr19_+_46222428 0.24 ENSDART00000183984
vacuolar protein sorting 28 (yeast)
chr19_-_44054930 0.24 ENSDART00000151084
ENSDART00000150991
ENSDART00000005191
ubiquinol-cytochrome c reductase binding protein
chr16_+_24681177 0.23 ENSDART00000058956
ENSDART00000189335
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
chr7_-_12909352 0.23 ENSDART00000172901
SH3-domain GRB2-like 3a
chr10_+_39091716 0.22 ENSDART00000193072
si:ch73-1a9.4
chr5_+_26921033 0.21 ENSDART00000051483
TM2 domain containing 2
chr24_-_41657005 0.20 ENSDART00000159109

chr3_-_11624694 0.19 ENSDART00000127157
hepatic leukemia factor a
chr23_-_5759242 0.19 ENSDART00000055087
pleckstrin homology-like domain, family A, member 3
chr6_+_12462079 0.19 ENSDART00000192029
ENSDART00000065385
nuclear receptor subfamily 4, group A, member 2b
chr23_+_17220986 0.19 ENSDART00000054761
nucleolar protein 4-like b
chr6_+_58832155 0.19 ENSDART00000144842
dynactin 2 (p50)
chr5_+_57715614 0.18 ENSDART00000037181
ubiquitin-fold modifier conjugating enzyme 1
chr1_-_51062405 0.18 ENSDART00000006381
presenilin 2
chr8_+_49433663 0.18 ENSDART00000140481
ENSDART00000180714
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr23_-_27506161 0.18 ENSDART00000145007
ankyrin repeat and SOCS box containing 8
chr4_+_9011825 0.18 ENSDART00000058007
sorting and assembly machinery component 50 homolog, like
chr20_-_32446406 0.17 ENSDART00000026635
nuclear receptor subfamily 2, group E, member 1
chr15_-_1844048 0.17 ENSDART00000102410
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr6_+_7249531 0.17 ENSDART00000125912
ENSDART00000083424
ENSDART00000049695
ENSDART00000136088
DAZ interacting zinc finger protein 1
chr25_-_36044583 0.17 ENSDART00000073432
retinoblastoma-like 2 (p130)
chr17_-_8674208 0.17 ENSDART00000149201
C-terminal binding protein 2a
chr13_+_17702853 0.17 ENSDART00000145438
si:dkey-27m7.4
chr24_-_35534273 0.17 ENSDART00000026578
ubiquitin-conjugating enzyme E2 variant 2
chr24_-_12689571 0.16 ENSDART00000015517
programmed cell death 6
chr15_-_34658057 0.16 ENSDART00000110964
BCL2 associated athanogene 6
chr20_+_16639848 0.16 ENSDART00000063944
ENSDART00000152359
transmembrane protein 30Ab
chr13_+_17702522 0.16 ENSDART00000057913
si:dkey-27m7.4
chr18_+_25752592 0.16 ENSDART00000111767
si:ch211-39k3.2
chr19_+_20163826 0.15 ENSDART00000090942
ENSDART00000134650
coiled-coil domain containing 126
chr8_+_40628926 0.15 ENSDART00000163598
dual specificity phosphatase 2
chr2_+_30103131 0.15 ENSDART00000185119
DnaJ (Hsp40) homolog, subfamily B, member 6a
chr2_-_19354622 0.15 ENSDART00000168627
zinc finger, FYVE domain containing 9a
chr14_-_6225336 0.14 ENSDART00000111681
highly divergent homeobox
chr16_-_13613475 0.13 ENSDART00000139102
D site albumin promoter binding protein b
chr4_+_40953320 0.12 ENSDART00000151912
zinc finger protein 1136
chr18_+_6857071 0.12 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr3_+_61221194 0.11 ENSDART00000110030
lemur tyrosine kinase 2
chr23_+_33963619 0.11 ENSDART00000140666
ENSDART00000084792
pyridoxal phosphate binding protein
chr12_+_33320504 0.11 ENSDART00000021491
casein kinase 1, delta b
chr20_-_51727860 0.11 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr5_-_25576462 0.11 ENSDART00000165147
si:dkey-229d2.4
chr18_+_38775277 0.11 ENSDART00000186129
family with sequence similarity 214, member A
chr2_-_10386738 0.10 ENSDART00000016369
wntless Wnt ligand secretion mediator
chr10_-_41906609 0.10 ENSDART00000102530
lysine (K)-specific demethylase 2Bb
chr6_+_58832323 0.10 ENSDART00000042595
dynactin 2 (p50)
chr1_-_23596391 0.10 ENSDART00000155184
ligand dependent nuclear receptor corepressor-like
chr11_+_45255774 0.10 ENSDART00000172838
alveolar soft part sarcoma chromosome region, candidate 1
chr12_+_48204891 0.09 ENSDART00000190534
ENSDART00000164427
nodal-related 2
chr25_+_36045072 0.09 ENSDART00000126326
RPGRIP1-like
chr6_+_52212574 0.09 ENSDART00000025940
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr10_+_44940693 0.09 ENSDART00000157515
cyclin and CBS domain divalent metal cation transport mediator 4a
chr23_-_41824460 0.08 ENSDART00000131235
si:ch73-302a13.2
chr10_-_9089545 0.08 ENSDART00000080781
ADP-ribosylation factor-like 15b
chr6_+_52350443 0.08 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr18_+_29402623 0.07 ENSDART00000014703
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr14_+_31493119 0.07 ENSDART00000006463
PHD finger protein 6
chr12_+_33320884 0.07 ENSDART00000188988
casein kinase 1, delta b
chr23_-_3409140 0.07 ENSDART00000002309
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr22_-_4760187 0.07 ENSDART00000081969
RAD23 homolog A, nucleotide excision repair protein b
chr24_-_37326236 0.07 ENSDART00000003789
3-phosphoinositide dependent protein kinase 1b
chr15_-_34845414 0.07 ENSDART00000009892
gamma-aminobutyric acid (GABA) B receptor, 1a
chr3_+_40284598 0.06 ENSDART00000009411
BUD31 homolog (S. cerevisiae)
chr7_+_22616212 0.06 ENSDART00000052844
claudin 7a
chr8_-_29822527 0.06 ENSDART00000167487
solute carrier family 20 (phosphate transporter), member 2
chr8_-_45838277 0.06 ENSDART00000046064
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr12_+_36109507 0.06 ENSDART00000175409
mitogen-activated protein kinase kinase 6
chr8_-_19266325 0.06 ENSDART00000036148
ENSDART00000137994
zgc:77486
chr8_+_23147218 0.06 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
GID complex subunit 8 homolog a (S. cerevisiae)
chr1_-_55166511 0.06 ENSDART00000150430
ENSDART00000035725
proliferation associated nuclear element
chr21_-_9782502 0.05 ENSDART00000158836
Rho GTPase activating protein 24
chr23_-_32157865 0.05 ENSDART00000000876
nuclear receptor subfamily 4, group A, member 1
chr9_-_11655031 0.05 ENSDART00000044314
integrin, alpha V
chr17_-_9995667 0.05 ENSDART00000148463
sorting nexin 6
chr14_+_30413758 0.05 ENSDART00000092953
CCR4-NOT transcription complex, subunit 7
chr15_-_5892650 0.05 ENSDART00000154812
bromodomain and WD repeat domain containing 1
chr8_-_410199 0.05 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
tripartite motif containing 36
chr5_+_36439405 0.04 ENSDART00000102973
ectodysplasin A
chr16_-_4770233 0.03 ENSDART00000193228
replication protein A2
chr14_+_31493306 0.03 ENSDART00000138341
PHD finger protein 6
chr15_-_1843831 0.03 ENSDART00000156718
ENSDART00000154175
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr3_-_15487111 0.03 ENSDART00000011320
nuclear factor of activated T cells 2 interacting protein
chr17_+_1544903 0.02 ENSDART00000156244
ENSDART00000112183
centrosomal protein 170B
chr12_-_34852342 0.02 ENSDART00000152968
si:dkey-21c1.1
chr23_-_3408777 0.02 ENSDART00000193245
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr23_+_17509794 0.02 ENSDART00000148457
GID complex subunit 8 homolog b (S. cerevisiae)
chr1_-_46632948 0.01 ENSDART00000148893
ENSDART00000053232
cytidine and dCMP deaminase domain containing 1
chr17_-_8673567 0.01 ENSDART00000192714
ENSDART00000012546
C-terminal binding protein 2a
chr4_+_9011448 0.01 ENSDART00000192357
sorting and assembly machinery component 50 homolog, like
chr3_+_18555899 0.01 ENSDART00000163036
ENSDART00000158791
chromobox homolog 4 (Pc class homolog, Drosophila)
chr25_-_34845302 0.01 ENSDART00000039485
GABA(A) receptor-associated protein like 2
chr3_+_26019426 0.01 ENSDART00000135389
ENSDART00000182411
FAD-dependent oxidoreductase domain containing 2
chr22_-_26834043 0.01 ENSDART00000087202
si:dkey-44g23.5
chr10_-_26744131 0.01 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr3_-_40284744 0.00 ENSDART00000018626
pdgfa associated protein 1b
chr25_-_34632050 0.00 ENSDART00000170671
multiple EGF-like-domains 8
chr14_-_31619408 0.00 ENSDART00000173277
membrane magnesium transporter 1

Network of associatons between targets according to the STRING database.

First level regulatory network of e4f1+si:dkeyp-79b7.12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.6 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.1 0.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.4 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.8 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 1.2 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.3 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.1 1.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.2 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.3 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.3 GO:0031627 telomeric loop formation(GO:0031627)
0.1 1.1 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.5 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.0 0.5 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0034205 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.2 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0021742 abducens nucleus development(GO:0021742)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.3 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 1.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 1.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.2 0.5 GO:0038046 enkephalin receptor activity(GO:0038046)
0.1 0.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.2 GO:0051117 ATPase binding(GO:0051117)
0.1 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0005035 death receptor activity(GO:0005035)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 2.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport