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PRJNA207719: Tissue specific transcriptome profiling

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Results for egr1

Z-value: 0.81

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Transcription factors associated with egr1

Gene Symbol Gene ID Gene Info
egr1
ENSDARG00000037421 early growth response 1
egr1
ENSDARG00000115563 early growth response 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
egr1dr11_v1_chr14_-_21336385_213363850.296.3e-01Click!

Activity profile of egr1 motif

Sorted Z-values of egr1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_22535 1.74 ENSDART00000157877
CABZ01092282.1

chr20_-_54462551 0.96 ENSDART00000171769
ENSDART00000169692
evlb
Enah/Vasp-like b
chr2_-_48753873 0.82 ENSDART00000189556
CABZ01044731.1

chr23_+_37323962 0.67 ENSDART00000102881
fam43b
family with sequence similarity 43, member B
chr2_+_47582681 0.65 ENSDART00000187579
scg2b
secretogranin II (chromogranin C), b
chr2_+_47582488 0.63 ENSDART00000149967
scg2b
secretogranin II (chromogranin C), b
chr24_+_24923166 0.61 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr2_+_38924975 0.59 ENSDART00000109219
rem2
RAS (RAD and GEM)-like GTP binding 2
chr25_+_34984333 0.53 ENSDART00000154760
ccdc136b
coiled-coil domain containing 136b
chr9_-_18877597 0.51 ENSDART00000099446
kctd4
potassium channel tetramerization domain containing 4
chr18_+_18612388 0.50 ENSDART00000186455
st3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr23_+_41799748 0.50 ENSDART00000144257
pdyn
prodynorphin
chr17_-_14726824 0.45 ENSDART00000162947
si:ch73-305o9.3
si:ch73-305o9.3
chr13_+_12739283 0.42 ENSDART00000102279
lingo2b
leucine rich repeat and Ig domain containing 2b
chr20_-_45661049 0.42 ENSDART00000124582
ENSDART00000131251
napbb
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr3_-_61185746 0.40 ENSDART00000028219
pvalb4
parvalbumin 4
chr1_-_7917062 0.38 ENSDART00000177068
mmd2b
monocyte to macrophage differentiation-associated 2b
chr13_-_21739142 0.38 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr6_-_35446110 0.37 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr8_+_24854600 0.37 ENSDART00000156570
slc6a17
solute carrier family 6 (neutral amino acid transporter), member 17
chr23_+_20422661 0.36 ENSDART00000144047
ENSDART00000104336
tnnc2
troponin C type 2 (fast)
chr21_+_28958471 0.36 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_-_20611039 0.36 ENSDART00000170422
si:dkey-19b23.8
si:dkey-19b23.8
chr16_-_6821927 0.35 ENSDART00000149070
ENSDART00000149570
mbpb
myelin basic protein b
chr23_+_2136344 0.35 ENSDART00000085290
ENSDART00000092757
cpeb2
cytoplasmic polyadenylation element binding protein 2
chr12_+_47448558 0.34 ENSDART00000185689
ENSDART00000105328
fmn2b
formin 2b
chr9_-_54001502 0.34 ENSDART00000085253
mid1
midline 1
chr10_-_32851847 0.34 ENSDART00000134255
trim37
tripartite motif containing 37
chr1_+_32528097 0.33 ENSDART00000128317
nlgn4a
neuroligin 4a
chr20_-_915234 0.33 ENSDART00000164816
cnr1
cannabinoid receptor 1
chr6_+_34512313 0.33 ENSDART00000102554
lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr15_-_19250543 0.33 ENSDART00000092705
ENSDART00000138895
igsf9ba
immunoglobulin superfamily, member 9Ba
chr9_-_24413008 0.33 ENSDART00000135897
tmeff2a
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr4_-_9586713 0.32 ENSDART00000145613
shank3b
SH3 and multiple ankyrin repeat domains 3b
chr12_-_850457 0.32 ENSDART00000022688
tob1b
transducer of ERBB2, 1b
chr18_-_19103929 0.32 ENSDART00000188370
ENSDART00000177621
dennd4a
DENN/MADD domain containing 4A
chr14_-_7888748 0.31 ENSDART00000166293
ppp3cb
protein phosphatase 3, catalytic subunit, beta isozyme
chr1_+_54673846 0.31 ENSDART00000145018
gprc5bb
G protein-coupled receptor, class C, group 5, member Bb
chr6_-_15604417 0.31 ENSDART00000157817
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr25_+_35706493 0.30 ENSDART00000176741
kif21a
kinesin family member 21A
chr21_+_11415224 0.30 ENSDART00000049036
zgc:92275
zgc:92275
chr25_+_1304173 0.29 ENSDART00000155229
rxfp3.3b
relaxin/insulin-like family peptide receptor 3.3b
chr25_+_21177326 0.29 ENSDART00000149142
erc1a
ELKS/RAB6-interacting/CAST family member 1a
chr6_-_15604157 0.29 ENSDART00000141597
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr17_+_15983247 0.29 ENSDART00000154275
clmn
calmin
chr6_+_34511886 0.29 ENSDART00000179450
lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr22_+_15979430 0.28 ENSDART00000189703
ENSDART00000192674
rc3h1a
ring finger and CCCH-type domains 1a
chr25_+_21176937 0.28 ENSDART00000163751
ENSDART00000188930
ENSDART00000187155
erc1a
ELKS/RAB6-interacting/CAST family member 1a
chr15_-_12319065 0.28 ENSDART00000162973
ENSDART00000170543
fxyd6
FXYD domain containing ion transport regulator 6
chr25_+_34888886 0.28 ENSDART00000035245
spire2
spire-type actin nucleation factor 2
chr6_-_25181012 0.28 ENSDART00000161585
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr12_+_48511605 0.27 ENSDART00000168389
arhgap44
Rho GTPase activating protein 44
chr13_+_9432501 0.27 ENSDART00000058064
zgc:123321
zgc:123321
chr14_-_21218891 0.27 ENSDART00000158294
ppp2r2cb
protein phosphatase 2, regulatory subunit B, gamma b
chr5_-_21524251 0.27 ENSDART00000176793
ENSDART00000040184
tenm1
teneurin transmembrane protein 1
chr2_-_17827983 0.27 ENSDART00000166518
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr3_-_6767440 0.26 ENSDART00000156174
mast1b
microtubule associated serine/threonine kinase 1b
chr25_+_34889061 0.25 ENSDART00000136226
spire2
spire-type actin nucleation factor 2
chr6_+_21740672 0.25 ENSDART00000193734
lhfpl4a
lipoma HMGIC fusion partner-like 4a
chr15_-_20939579 0.25 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr6_+_59808677 0.24 ENSDART00000164469
caskb
calcium/calmodulin-dependent serine protein kinase b
chr5_+_65492183 0.24 ENSDART00000162804
si:dkey-21e5.1
si:dkey-21e5.1
chr4_-_5019113 0.24 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr22_-_3564563 0.23 ENSDART00000145114
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr21_+_26620867 0.23 ENSDART00000176008
esrra
estrogen-related receptor alpha
chr15_+_3284684 0.23 ENSDART00000179778
foxo1a
forkhead box O1 a
chr8_-_39903803 0.23 ENSDART00000012391
cabp1a
calcium binding protein 1a
chr1_-_20271138 0.23 ENSDART00000185931
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_+_1599979 0.23 ENSDART00000097626
urp2
urotensin II-related peptide
chr15_+_43906043 0.23 ENSDART00000010881
naalad2
N-acetylated alpha-linked acidic dipeptidase 2
chr12_-_48943467 0.22 ENSDART00000191829
CABZ01092907.1

chr2_-_17828279 0.22 ENSDART00000083314
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr6_+_42819337 0.22 ENSDART00000046498
sema3fa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr23_+_41800052 0.21 ENSDART00000141484
pdyn
prodynorphin
chr18_+_3169579 0.21 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr11_-_2594045 0.21 ENSDART00000114079
nab2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr19_+_342094 0.21 ENSDART00000151013
ENSDART00000187622
ensaa
endosulfine alpha a
chr23_-_31645760 0.20 ENSDART00000035031
sgk1
serum/glucocorticoid regulated kinase 1
chr24_+_32472155 0.20 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr15_-_14486534 0.20 ENSDART00000179368
numbl
numb homolog (Drosophila)-like
chr2_-_155270 0.20 ENSDART00000131177
adcy1b
adenylate cyclase 1b
chr4_-_5018705 0.20 ENSDART00000154025
strip2
striatin interacting protein 2
chr16_+_52105227 0.19 ENSDART00000150025
ENSDART00000097863
MAN1C1
si:ch73-373m9.1
chr15_+_3284416 0.19 ENSDART00000187665
ENSDART00000171723
foxo1a
forkhead box O1 a
chr5_+_37032038 0.19 ENSDART00000045036
nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr21_+_7900107 0.18 ENSDART00000056560
ch25hl2
cholesterol 25-hydroxylase like 2
chr9_-_41401564 0.18 ENSDART00000059628
nab1b
NGFI-A binding protein 1b (EGR1 binding protein 1)
chr21_-_24865217 0.18 ENSDART00000101136
igsf9bb
immunoglobulin superfamily, member 9Bb
chr12_-_15620090 0.18 ENSDART00000038032
acbd4
acyl-CoA binding domain containing 4
chr3_-_22829710 0.18 ENSDART00000055659
cyb561
cytochrome b561
chr21_+_27513859 0.18 ENSDART00000065420
pacs1a
phosphofurin acidic cluster sorting protein 1a
chr5_+_15667874 0.18 ENSDART00000127015
srrm4
serine/arginine repetitive matrix 4
chr9_-_30363770 0.18 ENSDART00000147030
sytl5
synaptotagmin-like 5
chr25_-_7999756 0.17 ENSDART00000159908
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr18_+_16246806 0.17 ENSDART00000142584
alx1
ALX homeobox 1
chr12_+_48851381 0.17 ENSDART00000187241
ENSDART00000187796
dlg5b.1
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr1_-_8917902 0.17 ENSDART00000137900
grin2ab
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr12_+_41510492 0.17 ENSDART00000170976
ENSDART00000176164
kif5bb
kinesin family member 5B, b
chr17_+_15983557 0.16 ENSDART00000190806
clmn
calmin
chr1_-_625875 0.16 ENSDART00000167331
appa
amyloid beta (A4) precursor protein a
chr25_+_12012 0.16 ENSDART00000170348
cntn1a
contactin 1a
chr2_+_50062165 0.16 ENSDART00000097939
ENSDART00000138214
zcchc2
zinc finger, CCHC domain containing 2
chr20_+_32523576 0.16 ENSDART00000147319
scml4
Scm polycomb group protein like 4
chr14_+_7939398 0.16 ENSDART00000189773
cxxc5b
CXXC finger protein 5b
chr2_+_57864307 0.15 ENSDART00000191981
plekhj1
pleckstrin homology domain containing, family J member 1
chr2_-_24603325 0.15 ENSDART00000113356
crtc1a
CREB regulated transcription coactivator 1a
chr18_+_15106518 0.15 ENSDART00000168639
cry1ab
cryptochrome circadian clock 1ab
chr21_-_24865454 0.15 ENSDART00000142907
igsf9bb
immunoglobulin superfamily, member 9Bb
chr3_-_42016693 0.15 ENSDART00000184741
ttyh3a
tweety family member 3a
chr11_-_277599 0.14 ENSDART00000187109
npffl
neuropeptide FF-amide peptide precursor like
chr11_-_37880492 0.14 ENSDART00000102868
etnk2
ethanolamine kinase 2
chr6_+_11026866 0.14 ENSDART00000189619
abcc6a
ATP-binding cassette, sub-family C (CFTR/MRP), member 6a
chr2_-_48966431 0.14 ENSDART00000147948
kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr25_+_29688671 0.14 ENSDART00000073478
brd1b
bromodomain containing 1b
chr23_+_44665230 0.14 ENSDART00000144958
camta2
calmodulin binding transcription activator 2
chr8_-_14144707 0.14 ENSDART00000148061
si:dkey-6n6.1
si:dkey-6n6.1
chr25_-_37501371 0.14 ENSDART00000160498
CABZ01088346.1

chr8_+_28724692 0.14 ENSDART00000140115
ccser1
coiled-coil serine-rich protein 1
chr20_+_27087539 0.13 ENSDART00000062094
tmem251
transmembrane protein 251
chr20_-_54377933 0.13 ENSDART00000182664
entpd5b
ectonucleoside triphosphate diphosphohydrolase 5b
chr23_-_27547931 0.13 ENSDART00000144419
larp4aa
La ribonucleoprotein domain family, member 4Aa
chr5_-_67241633 0.13 ENSDART00000114783
clip1a
CAP-GLY domain containing linker protein 1a
chr19_-_3303995 0.13 ENSDART00000105150
si:ch211-133n4.9
si:ch211-133n4.9
chr14_-_4044545 0.13 ENSDART00000169527
snx25
sorting nexin 25
chr22_+_10713713 0.12 ENSDART00000122349
hiat1b
hippocampus abundant transcript 1b
chr20_-_54381034 0.12 ENSDART00000136779
entpd5b
ectonucleoside triphosphate diphosphohydrolase 5b
chr6_+_11026354 0.12 ENSDART00000065433
abcc6a
ATP-binding cassette, sub-family C (CFTR/MRP), member 6a
chr2_+_23701613 0.12 ENSDART00000047073
oxsr1a
oxidative stress responsive 1a
chr1_-_10473630 0.12 ENSDART00000040116
tnrc5
trinucleotide repeat containing 5
chr7_+_31051213 0.12 ENSDART00000148347
tjp1a
tight junction protein 1a
chr24_+_3328354 0.12 ENSDART00000147468
bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr25_-_6389713 0.12 ENSDART00000083539
sin3aa
SIN3 transcription regulator family member Aa
chr22_-_34872533 0.12 ENSDART00000167176
slit1b
slit homolog 1b (Drosophila)
chr13_-_49666615 0.11 ENSDART00000148083
tomm20a
translocase of outer mitochondrial membrane 20
chr4_-_9579299 0.11 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
shank3b
SH3 and multiple ankyrin repeat domains 3b
chr8_+_20438884 0.11 ENSDART00000016422
ENSDART00000133794
mknk2b
MAP kinase interacting serine/threonine kinase 2b
chr1_-_29761086 0.10 ENSDART00000136760
alg11
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr9_+_38075851 0.10 ENSDART00000135314
cacnb4a
calcium channel, voltage-dependent, beta 4a subunit
chr13_-_479129 0.10 ENSDART00000159803
ENSDART00000082127
heatr5b
HEAT repeat containing 5B
chr7_+_31051603 0.10 ENSDART00000108721
tjp1a
tight junction protein 1a
chr17_-_25831569 0.10 ENSDART00000148743
hhat
hedgehog acyltransferase
chr1_+_12295142 0.10 ENSDART00000158595
gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr3_+_19299309 0.10 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr20_-_26383368 0.10 ENSDART00000024518
ENSDART00000087844
esr1
estrogen receptor 1
chr13_+_30172142 0.10 ENSDART00000169917
ENSDART00000182091
pald1b
phosphatase domain containing, paladin 1b
chr7_+_20017211 0.09 ENSDART00000100808
bcl6b
B-cell CLL/lymphoma 6, member B
chr1_+_55293424 0.09 ENSDART00000152464
zgc:172106
zgc:172106
chr11_+_77526 0.09 ENSDART00000193521
CABZ01072242.1

chr1_-_50438247 0.09 ENSDART00000114098
dkk2
dickkopf WNT signaling pathway inhibitor 2
chr8_+_45294767 0.08 ENSDART00000191527
ubap2b
ubiquitin associated protein 2b
chr20_+_28803642 0.08 ENSDART00000188526
fntb
farnesyltransferase, CAAX box, beta
chr7_-_12596727 0.08 ENSDART00000186413
adamtsl3
ADAMTS-like 3
chr24_+_26379441 0.08 ENSDART00000137786
si:ch211-230g15.5
si:ch211-230g15.5
chr12_-_37449396 0.08 ENSDART00000152951
cdc42ep4b
CDC42 effector protein (Rho GTPase binding) 4b
chr22_+_38192568 0.08 ENSDART00000126323
cp
ceruloplasmin
chr11_+_25296366 0.07 ENSDART00000065949
top1l
DNA topoisomerase I, like
chr1_-_48922273 0.07 ENSDART00000150254
si:ch211-112b1.2
si:ch211-112b1.2
chr4_-_23839789 0.07 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr11_+_2699951 0.07 ENSDART00000082512
tmem167b
transmembrane protein 167B
chr16_+_4138331 0.07 ENSDART00000192403
ENSDART00000193036
mtf1
metal-regulatory transcription factor 1
chr19_-_2115040 0.07 ENSDART00000020497
snx13
sorting nexin 13
chr19_+_935565 0.07 ENSDART00000113368
RNF5
ring finger protein 5
chr23_+_9057999 0.06 ENSDART00000091899
ccm2l
cerebral cavernous malformation 2-like
chr14_+_36220479 0.06 ENSDART00000148319
pitx2
paired-like homeodomain 2
chr23_+_45822935 0.06 ENSDART00000161892
vdra
vitamin D receptor a
chr1_-_17693273 0.06 ENSDART00000146258
cfap97
cilia and flagella associated protein 97
chr9_+_45227028 0.06 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr3_+_45687266 0.06 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr3_+_16722014 0.05 ENSDART00000008711
gys1
glycogen synthase 1 (muscle)
chr11_+_2855430 0.05 ENSDART00000172837
kif21b
kinesin family member 21B
chr18_-_50956280 0.05 ENSDART00000058457
st7
suppression of tumorigenicity 7
chr2_+_20793982 0.05 ENSDART00000014785
prg4a
proteoglycan 4a
chr13_+_25486608 0.05 ENSDART00000057689
bag3
BCL2 associated athanogene 3
chr1_-_59422880 0.05 ENSDART00000167244
si:ch211-188p14.2
si:ch211-188p14.2
chr3_-_15444396 0.05 ENSDART00000104361
si:dkey-56d12.4
si:dkey-56d12.4
chr6_+_2271559 0.05 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b
chr19_+_2619444 0.05 ENSDART00000169483
fam126a
family with sequence similarity 126, member A
chr18_-_50845804 0.05 ENSDART00000158517
PDPR
si:cabz01113374.3
chr19_-_48039400 0.05 ENSDART00000166748
ENSDART00000165921
csf3b
colony stimulating factor 3 (granulocyte) b
chr3_-_37571601 0.04 ENSDART00000016407
arf2a
ADP-ribosylation factor 2a
chr9_+_51784922 0.04 ENSDART00000125850
cd302
CD302 molecule
chr2_+_23062085 0.04 ENSDART00000153745
csnk1g2a
casein kinase 1, gamma 2a
chr10_+_23548674 0.04 ENSDART00000079686
zmp:0000001103
zmp:0000001103
chr9_+_38369872 0.04 ENSDART00000193914
plcd4b
phospholipase C, delta 4b
chr14_+_12316581 0.04 ENSDART00000170115
ENSDART00000149757
si:ch211-125c23.3
cx31.7
si:ch211-125c23.3
connexin 31.7
chr23_+_25856541 0.04 ENSDART00000145426
ENSDART00000028236
hnf4a
hepatocyte nuclear factor 4, alpha
chr21_+_103194 0.04 ENSDART00000162755
zer1
zyg-11 related, cell cycle regulator
chr20_+_54356272 0.04 ENSDART00000145735
znf410
zinc finger protein 410
chr10_+_11282883 0.03 ENSDART00000135355
si:ch211-126i22.5
si:ch211-126i22.5
chr6_+_42818963 0.03 ENSDART00000184833
sema3fa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr25_-_207214 0.03 ENSDART00000193448
FP236318.3

chr19_+_43504480 0.03 ENSDART00000159421
BX649384.3

chr20_-_48172556 0.03 ENSDART00000097888
CABZ01059099.1

chr20_+_13894123 0.03 ENSDART00000007744
slc30a1a
solute carrier family 30 (zinc transporter), member 1a
chr5_+_66170479 0.03 ENSDART00000172117
gldc
glycine dehydrogenase (decarboxylating)
chr7_-_24995631 0.03 ENSDART00000173955
ENSDART00000173791
rcor2
REST corepressor 2
chr12_+_499881 0.03 ENSDART00000167527
mprip
myosin phosphatase Rho interacting protein
chr22_+_34784075 0.03 ENSDART00000167538
lcor
ligand dependent nuclear receptor corepressor
chr1_+_49435017 0.03 ENSDART00000124833
pdcd11
programmed cell death 11
chr10_-_14920989 0.03 ENSDART00000184617
smad2
SMAD family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of egr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015824 proline transport(GO:0015824)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.5 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.3 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.4 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.4 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.6 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.3 GO:2000253 cannabinoid signaling pathway(GO:0038171) positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0010662 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 1.1 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.2 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.4 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.7 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.7 GO:0043679 axon terminus(GO:0043679)
0.0 0.3 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 1.1 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.7 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.6 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE