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PRJNA207719: Tissue specific transcriptome profiling
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Results for etv7
Z-value: 1.38
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Transcription factors associated with etv7
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| etv7 | dr11_v1_chr23_-_5101847_5101847 | 0.73 | 1.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_18254 Show fit | 0.78 |
ENSDART00000167814
|
proline rich 13 |
|
| chr11_-_18449 Show fit | 0.77 |
ENSDART00000172050
|
proline rich 13 |
|
| chr6_+_52212574 Show fit | 0.63 |
ENSDART00000025940
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a |
|
| chr8_-_45430817 Show fit | 0.59 |
ENSDART00000150067
ENSDART00000112394 |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b |
|
| chr6_+_52212927 Show fit | 0.59 |
ENSDART00000143458
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a |
|
| chr22_+_16535575 Show fit | 0.56 |
ENSDART00000083063
|
T-cell acute lymphocytic leukemia 1 |
|
| chr20_-_1439256 Show fit | 0.52 |
ENSDART00000002928
|
thymocyte selection associated |
|
| chr6_-_57426097 Show fit | 0.48 |
ENSDART00000171531
|
zinc finger, NFX1-type containing 1 |
|
| chr16_-_45001842 Show fit | 0.43 |
ENSDART00000037797
|
sulfotransferase family 2, cytosolic sulfotransferase 3 |
|
| chr8_+_52530889 Show fit | 0.42 |
ENSDART00000127729
ENSDART00000170360 ENSDART00000162687 |
STAM binding protein b |
Network of associatons between targets according to the STRING database.
First level regulatory network of etv7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.2 | 0.6 | GO:0045601 | regulation of endothelial cell differentiation(GO:0045601) |
| 0.1 | 0.6 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.2 | 0.5 | GO:0043383 | negative T cell selection(GO:0043383) |
| 0.0 | 0.5 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.1 | 0.4 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
| 0.1 | 0.4 | GO:0031048 | chromatin silencing by small RNA(GO:0031048) |
| 0.1 | 0.4 | GO:0009180 | ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) |
| 0.0 | 0.4 | GO:2001032 | positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 0.0 | 0.4 | GO:1901654 | response to ketone(GO:1901654) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 0.5 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.4 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 0.4 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 0.3 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.3 | GO:0032783 | ELL-EAF complex(GO:0032783) |
| 0.0 | 0.3 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.0 | 0.3 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.3 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.0 | 0.3 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.6 | GO:0070122 | isopeptidase activity(GO:0070122) |
| 0.0 | 0.4 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 0.3 | GO:0008119 | thiopurine S-methyltransferase activity(GO:0008119) |
| 0.0 | 0.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.3 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 0.2 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.2 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.0 | 0.2 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.0 | 0.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.4 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.3 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.0 | 0.3 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.2 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.0 | 0.2 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.1 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |