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PRJNA207719: Tissue specific transcriptome profiling

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Results for figla

Z-value: 2.27

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Transcription factors associated with figla

Gene Symbol Gene ID Gene Info
figla
ENSDARG00000087166 folliculogenesis specific bHLH transcription factor
figla
ENSDARG00000115572 folliculogenesis specific bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
figladr11_v1_chr5_-_13848296_13848296-0.306.3e-01Click!

Activity profile of figla motif

Sorted Z-values of figla motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_30404096 4.07 ENSDART00000103475
agr2
anterior gradient 2
chr19_-_30403922 3.23 ENSDART00000181841
agr2
anterior gradient 2
chr7_-_35066457 2.43 ENSDART00000058067
zgc:112160
zgc:112160
chr22_-_17677947 2.17 ENSDART00000139911
tjp3
tight junction protein 3
chr2_+_15612755 2.06 ENSDART00000003035
amy2a
amylase, alpha 2A (pancreatic)
chr23_-_29824146 2.05 ENSDART00000020616
zgc:194189
zgc:194189
chr20_-_21672970 2.01 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr4_+_5537101 1.99 ENSDART00000008692
si:dkey-14d8.7
si:dkey-14d8.7
chr7_+_2455344 1.98 ENSDART00000172942
si:dkey-125e8.4
si:dkey-125e8.4
chr5_-_29531948 1.94 ENSDART00000098360
arrdc1a
arrestin domain containing 1a
chr17_+_26965351 1.88 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr22_+_11756040 1.88 ENSDART00000105808
krt97
keratin 97
chr4_+_5531583 1.83 ENSDART00000137500
ENSDART00000042080
si:dkey-14d8.6
si:dkey-14d8.6
chr22_+_7439186 1.81 ENSDART00000190667
zgc:92041
zgc:92041
chr13_+_33606739 1.74 ENSDART00000026464
cfl1l
cofilin 1 (non-muscle), like
chr7_-_38644560 1.73 ENSDART00000114934
c6ast3
six-cysteine containing astacin protease 3
chr4_-_8040436 1.68 ENSDART00000113033
si:ch211-240l19.6
si:ch211-240l19.6
chr21_-_22647695 1.66 ENSDART00000187553
gig2l
grass carp reovirus (GCRV)-induced gene 2l
chr6_+_42918933 1.65 ENSDART00000064896
gnat1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr10_-_25217347 1.62 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr7_-_38644287 1.60 ENSDART00000182307
c6ast3
six-cysteine containing astacin protease 3
chr3_-_4612324 1.58 ENSDART00000101228
ftr50
finTRIM family, member 50
chr4_-_8043839 1.57 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
si:ch211-240l19.5
chr1_-_59104145 1.53 ENSDART00000132495
ENSDART00000152457
MFAP4 (1 of many)
si:zfos-2330d3.7
si:zfos-2330d3.1
si:zfos-2330d3.7
chr3_-_26204867 1.49 ENSDART00000103748
gdpd3a
glycerophosphodiester phosphodiesterase domain containing 3a
chr21_+_11776328 1.48 ENSDART00000134469
ENSDART00000081646
glrx
glutaredoxin (thioltransferase)
chr19_-_7110617 1.43 ENSDART00000104838
psmb8a
proteasome subunit beta 8A
chr8_+_29593986 1.43 ENSDART00000077642
atoh1a
atonal bHLH transcription factor 1a
chr22_+_7480465 1.41 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr3_+_36424055 1.40 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr8_+_6576940 1.37 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr14_+_34514336 1.36 ENSDART00000024440
foxi3b
forkhead box I3b
chr3_+_14641962 1.36 ENSDART00000091070
zgc:158403
zgc:158403
chr22_+_26400519 1.31 ENSDART00000159839
ENSDART00000144585
capn8
calpain 8
chr10_-_2942900 1.31 ENSDART00000002622
oclna
occludin a
chr25_+_5012791 1.31 ENSDART00000156970
si:ch73-265h17.5
si:ch73-265h17.5
chr14_+_22297257 1.30 ENSDART00000113676
atp10b
ATPase phospholipid transporting 10B
chr8_+_44358443 1.28 ENSDART00000189130
ENSDART00000189212
CU914776.2

chr16_-_26676685 1.27 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr7_+_57089354 1.26 ENSDART00000140702
scamp2l
secretory carrier membrane protein 2, like
chr9_+_17309195 1.25 ENSDART00000048548
scel
sciellin
chr15_+_34963316 1.24 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr3_+_34121156 1.22 ENSDART00000174929
aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr15_+_38299563 1.20 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr23_+_31815423 1.20 ENSDART00000075730
ENSDART00000075726
myb
v-myb avian myeloblastosis viral oncogene homolog
chr16_+_44768361 1.19 ENSDART00000036302
upk1a
uroplakin 1a
chr6_-_607063 1.15 ENSDART00000189900
lgals2b
lectin, galactoside-binding, soluble, 2b
chr19_+_31904836 1.14 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr7_+_58751504 1.11 ENSDART00000024185
zgc:56231
zgc:56231
chr6_+_56141852 1.10 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr19_+_7636941 1.10 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr18_+_36631923 1.08 ENSDART00000098980
znf296
zinc finger protein 296
chr3_+_49021079 1.08 ENSDART00000162012
zgc:163083
zgc:163083
chr6_-_8360918 1.08 ENSDART00000004716
acp5a
acid phosphatase 5a, tartrate resistant
chr16_+_17715243 1.05 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr5_+_57924611 1.04 ENSDART00000050949
btg4
B-cell translocation gene 4
chr16_+_34111919 1.03 ENSDART00000134037
ENSDART00000006061
ENSDART00000140552
tcea3
transcription elongation factor A (SII), 3
chr16_-_47381519 1.02 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
si:dkey-256h2.1
chr10_-_24784446 0.99 ENSDART00000140877
si:ch1073-15f19.2
si:ch1073-15f19.2
chr15_+_38299385 0.98 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr21_+_30351256 0.97 ENSDART00000078341
foxi3a
forkhead box I3a
chr2_-_50225411 0.97 ENSDART00000147117
ENSDART00000000042
mcm6l
MCM6 minichromosome maintenance deficient 6, like
chr6_+_54711306 0.96 ENSDART00000074605
pkp1b
plakophilin 1b
chr16_-_42066523 0.96 ENSDART00000180538
ENSDART00000058620
zp3d.1
zona pellucida glycoprotein 3d tandem duplicate 1
chr7_-_50367642 0.95 ENSDART00000134941
prc1b
protein regulator of cytokinesis 1b
chr4_-_12790886 0.92 ENSDART00000182535
ENSDART00000067131
ENSDART00000186426
irak3
interleukin-1 receptor-associated kinase 3
chr6_-_10788065 0.92 ENSDART00000190968
wipf1b
WAS/WASL interacting protein family, member 1b
chr12_-_46145635 0.91 ENSDART00000074682
zgc:153932
zgc:153932
chr3_-_32965848 0.90 ENSDART00000050930
casp6
caspase 6, apoptosis-related cysteine peptidase
chr7_-_50367326 0.90 ENSDART00000141926
prc1b
protein regulator of cytokinesis 1b
chr20_+_46371458 0.89 ENSDART00000152912
adgrg11
adhesion G protein-coupled receptor G11
chr13_+_31716820 0.89 ENSDART00000034745
prkcha
protein kinase C, eta, a
chr5_+_36932718 0.88 ENSDART00000037879
crx
cone-rod homeobox
chr9_-_34396264 0.87 ENSDART00000045754
grtp1b
growth hormone regulated TBC protein 1b
chr12_+_30360184 0.85 ENSDART00000190718
si:ch211-225b10.3
si:ch211-225b10.3
chr8_-_14554785 0.85 ENSDART00000057645
qsox1
quiescin Q6 sulfhydryl oxidase 1
chr23_+_25305431 0.85 ENSDART00000143291
RPL41
si:dkey-151g10.6
chr12_-_23365737 0.85 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr5_+_28271412 0.84 ENSDART00000031727
vamp8
vesicle-associated membrane protein 8 (endobrevin)
chr3_+_26245731 0.84 ENSDART00000103734
atad5a
ATPase family, AAA domain containing 5a
chr13_-_21672131 0.83 ENSDART00000067537
elovl6l
ELOVL family member 6, elongation of long chain fatty acids like
chr8_-_25247284 0.82 ENSDART00000132697
gnat2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr11_-_5865744 0.82 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr2_-_42628028 0.82 ENSDART00000179866
myo10
myosin X
chr5_-_69212184 0.81 ENSDART00000053963
mat2ab
methionine adenosyltransferase II, alpha b
chr10_+_29849977 0.81 ENSDART00000180242
hspa8
heat shock protein 8
chr10_+_29850330 0.81 ENSDART00000168898
hspa8
heat shock protein 8
chr24_-_2423791 0.81 ENSDART00000190402
rreb1a
ras responsive element binding protein 1a
chr15_-_29326254 0.81 ENSDART00000114492
si:dkey-52l18.4
si:dkey-52l18.4
chr14_+_32964 0.80 ENSDART00000166173
lyar
Ly1 antibody reactive homolog (mouse)
chr7_+_49664174 0.79 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr16_+_32152612 0.79 ENSDART00000008880
gprc6a
G protein-coupled receptor, class C, group 6, member A
chr25_-_17395315 0.78 ENSDART00000064596
cyp2x8
cytochrome P450, family 2, subfamily X, polypeptide 8
chr5_-_23696926 0.78 ENSDART00000021462
rnf128a
ring finger protein 128a
chr2_+_9560740 0.78 ENSDART00000003465
gipc2
GIPC PDZ domain containing family, member 2
chr7_-_48251234 0.78 ENSDART00000024062
ENSDART00000098904
cpeb1b
cytoplasmic polyadenylation element binding protein 1b
chr2_+_37762924 0.77 ENSDART00000156530
ftr66
finTRIM family, member 66
chr12_-_16990896 0.76 ENSDART00000152402
ifit12
interferon-induced protein with tetratricopeptide repeats 12
chr6_+_23057311 0.75 ENSDART00000026448
evpla
envoplakin a
chr9_-_29578037 0.75 ENSDART00000189026
cenpj
centromere protein J
chr6_-_52348562 0.75 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eif6
eukaryotic translation initiation factor 6
chr15_-_39969988 0.75 ENSDART00000146054
rps5
ribosomal protein S5
chr20_-_43743700 0.75 ENSDART00000100620
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr4_-_277081 0.74 ENSDART00000166174
si:ch73-252i11.1
si:ch73-252i11.1
chr16_+_19637384 0.73 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr17_+_5976683 0.72 ENSDART00000110276
zgc:194275
zgc:194275
chr11_-_28050559 0.72 ENSDART00000136859
ece1
endothelin converting enzyme 1
chr6_-_54290227 0.72 ENSDART00000050483
SPDEF
SAM pointed domain containing ETS transcription factor
chr13_-_14926318 0.71 ENSDART00000142785
cdc25b
cell division cycle 25B
chr11_+_25472758 0.70 ENSDART00000011178
opn1sw2
opsin 1 (cone pigments), short-wave-sensitive 2
chr9_-_40014339 0.69 ENSDART00000166918
IKZF2
si:zfos-1425h8.1
chr11_+_11504014 0.69 ENSDART00000104264
ENSDART00000134806
ENSDART00000132291
zgc:171226
zgc:171226
chr22_+_22021936 0.68 ENSDART00000149586
gna15.1
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr17_-_51195651 0.68 ENSDART00000191205
ENSDART00000088185
paplna
papilin a, proteoglycan-like sulfated glycoprotein
chr4_-_13614797 0.68 ENSDART00000138366
ENSDART00000165212
irf5
interferon regulatory factor 5
chr23_-_26532696 0.68 ENSDART00000124811
ENSDART00000180274
si:dkey-205h13.2
si:dkey-205h13.2
chr13_-_34683370 0.68 ENSDART00000113661
kif16bb
kinesin family member 16Bb
chr12_-_4176329 0.67 ENSDART00000092746
si:dkey-32n7.7
si:dkey-32n7.7
chr13_+_35955562 0.67 ENSDART00000137377
si:ch211-67f13.7
si:ch211-67f13.7
chr6_+_153146 0.67 ENSDART00000097468
zglp1
zinc finger, GATA-like protein 1
chr19_-_35035857 0.67 ENSDART00000103253
bmp8a
bone morphogenetic protein 8a
chr8_+_45334255 0.66 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr1_+_1915967 0.66 ENSDART00000131463
si:ch211-132g1.1
si:ch211-132g1.1
chr4_+_50401133 0.66 ENSDART00000150644
si:dkey-156k2.7
si:dkey-156k2.7
chr5_+_6670945 0.65 ENSDART00000185686
pxna
paxillin a
chr1_-_6085750 0.65 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr1_+_55723870 0.65 ENSDART00000146614
adgre17
adhesion G protein-coupled receptor E17
chr7_+_67699178 0.65 ENSDART00000160086
zgc:162592
zgc:162592
chr10_+_33171501 0.64 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr1_-_18752981 0.64 ENSDART00000188146
ENSDART00000193094
tbc1d1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr4_-_22363709 0.64 ENSDART00000037670
orc5
origin recognition complex, subunit 5
chr5_-_37900350 0.64 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
tmprss13b
transmembrane protease, serine 13b
chr22_+_20560041 0.64 ENSDART00000135490
nfil3-4
nuclear factor, interleukin 3 regulated, member 4
chr22_-_5006801 0.64 ENSDART00000106166
rx1
retinal homeobox gene 1
chr4_+_72797711 0.64 ENSDART00000190934
ENSDART00000163236
MYRFL
myelin regulatory factor-like
chr17_+_1360192 0.63 ENSDART00000184561
siva1
SIVA1, apoptosis-inducing factor
chr8_+_25359394 0.62 ENSDART00000111248
si:dkey-183p4.10
si:dkey-183p4.10
chr5_-_29152457 0.62 ENSDART00000078469
noxa1
NADPH oxidase activator 1
chr13_-_31025505 0.61 ENSDART00000137709
wdfy4
WDFY family member 4
chr5_-_22052852 0.61 ENSDART00000002938
mtmr8
myotubularin related protein 8
chr7_+_67699009 0.60 ENSDART00000192810
zgc:162592
zgc:162592
chr18_-_44316920 0.60 ENSDART00000098599
si:ch211-151h10.2
si:ch211-151h10.2
chr9_-_9989660 0.60 ENSDART00000081463
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr16_-_39570832 0.60 ENSDART00000039832
tgfbr2b
transforming growth factor beta receptor 2b
chr13_+_24584401 0.59 ENSDART00000057599
fuom
fucose mutarotase
chr21_-_34261677 0.59 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
alg13
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr23_-_44965582 0.59 ENSDART00000163367
tfr2
transferrin receptor 2
chr25_+_9003230 0.58 ENSDART00000180330
ENSDART00000142917
rag1
recombination activating gene 1
chr1_-_44157273 0.58 ENSDART00000166618
slc43a3a
solute carrier family 43, member 3a
chr17_+_5426087 0.57 ENSDART00000131430
ENSDART00000188636
runx2a
runt-related transcription factor 2a
chr23_-_1583193 0.57 ENSDART00000143841
fndc7b
fibronectin type III domain containing 7b
chr18_+_45666489 0.57 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr19_+_9666961 0.57 ENSDART00000104596
ENSDART00000132124
si:dkey-14o18.6
si:dkey-14o18.6
chr23_-_1017605 0.57 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr17_+_8799661 0.56 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr6_+_50452699 0.56 ENSDART00000115049
mych
myelocytomatosis oncogene homolog
chr3_+_53240562 0.56 ENSDART00000031234
stxbp2
syntaxin binding protein 2
chr16_-_45854882 0.56 ENSDART00000027013
ENSDART00000128068
ntrk1
neurotrophic tyrosine kinase, receptor, type 1
chr3_-_21094437 0.56 ENSDART00000153739
ENSDART00000109790
nlk1
nemo-like kinase, type 1
chr3_+_23221047 0.55 ENSDART00000009393
col1a1a
collagen, type I, alpha 1a
chr23_-_19831739 0.54 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr18_+_13248956 0.54 ENSDART00000080709
plcg2
phospholipase C, gamma 2
chr3_+_42923275 0.54 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr2_-_17114852 0.54 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr5_-_1047222 0.53 ENSDART00000181112
mbd2
methyl-CpG binding domain protein 2
chr25_+_8356707 0.53 ENSDART00000153708
muc5.1
mucin 5.1, oligomeric mucus/gel-forming
chr14_-_33277743 0.53 ENSDART00000048130
stard14
START domain containing 14
chr13_-_438705 0.53 ENSDART00000082142
CU570800.1

chr6_-_33978622 0.53 ENSDART00000151725
ENSDART00000124917
mpl
MPL proto-oncogene, thrombopoietin receptor
chr19_-_10432134 0.53 ENSDART00000081440
il11b
interleukin 11b
chr13_+_11876437 0.53 ENSDART00000179753
trim8a
tripartite motif containing 8a
chr14_-_33278084 0.53 ENSDART00000132850
stard14
START domain containing 14
chr8_-_43923788 0.53 ENSDART00000146152
adgrd1
adhesion G protein-coupled receptor D1
chr18_+_2228737 0.52 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr9_+_159720 0.52 ENSDART00000166215
cldn10l2
claudin 10-like 2
chr5_-_26181863 0.52 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr11_-_11336986 0.52 ENSDART00000016677
zgc:77929
zgc:77929
chr23_-_6865946 0.52 ENSDART00000056426
ftr58
finTRIM family, member 58
chr14_-_899170 0.52 ENSDART00000165211
ENSDART00000031992
rgs14a
regulator of G protein signaling 14a
chr24_+_35564668 0.51 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr12_-_28818720 0.51 ENSDART00000134453
ENSDART00000141727
prr15lb
proline rich 15-like b
chr8_+_40477264 0.51 ENSDART00000085559
gck
glucokinase (hexokinase 4)
chr23_-_1017428 0.51 ENSDART00000110588
ENSDART00000183158
cdh26.1
cadherin 26, tandem duplicate 1
chr2_+_21000334 0.51 ENSDART00000062563
ENSDART00000147809
rreb1b
ras responsive element binding protein 1b
chr2_+_27855346 0.51 ENSDART00000175159
ENSDART00000192645
buc
bucky ball
chr12_-_30359031 0.51 ENSDART00000192628
tdrd1
tudor domain containing 1
chr17_-_25331439 0.50 ENSDART00000155422
ENSDART00000082324
zpcx
zona pellucida protein C
chr23_-_30041065 0.50 ENSDART00000131209
ENSDART00000127192
ccdc187
coiled-coil domain containing 187
chr16_+_27444098 0.50 ENSDART00000157690
invs
inversin
chr5_-_15494164 0.49 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
taok3a
TAO kinase 3a
chr12_+_30360579 0.49 ENSDART00000152900
si:ch211-225b10.3
si:ch211-225b10.3
chr19_-_34927201 0.49 ENSDART00000076518
sla1
Src-like-adaptor 1
chr14_-_7409364 0.49 ENSDART00000036463
dnd1
DND microRNA-mediated repression inhibitor 1
chr1_+_20593653 0.49 ENSDART00000132440
si:ch211-142c4.1
si:ch211-142c4.1
chr17_+_6667441 0.49 ENSDART00000123503
ENSDART00000180381
ENSDART00000156140
smc6
structural maintenance of chromosomes 6
chr18_-_14337065 0.48 ENSDART00000135703
hsbp1b
heat shock factor binding protein 1b
chr8_-_8698607 0.47 ENSDART00000046712
zgc:86609
zgc:86609
chr5_+_58679071 0.47 ENSDART00000019561
zgc:171734
zgc:171734
chr15_-_5624361 0.47 ENSDART00000176446
ENSDART00000114410
wdr62
WD repeat domain 62
chr17_+_8799451 0.46 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein

Network of associatons between targets according to the STRING database.

First level regulatory network of figla

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.6 2.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.6 1.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.5 1.4 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.3 0.9 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.3 0.8 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.3 1.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.3 1.6 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.3 0.8 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.2 2.2 GO:0030104 water homeostasis(GO:0030104)
0.2 1.2 GO:0045658 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.2 1.9 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.2 0.8 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.2 1.0 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.2 1.7 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2 0.8 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 0.4 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045) hypoblast development(GO:0090008)
0.1 0.6 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 0.7 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.8 GO:0070254 mucus secretion(GO:0070254)
0.1 0.6 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.1 1.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 1.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.8 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.4 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 2.1 GO:0060046 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.9 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 1.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.8 GO:0061511 centriole elongation(GO:0061511)
0.1 0.3 GO:0090184 regulation of neurotransmitter uptake(GO:0051580) regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.6 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 0.7 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 0.6 GO:0006004 fucose metabolic process(GO:0006004)
0.1 3.8 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.1 GO:0045453 bone resorption(GO:0045453)
0.1 0.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.4 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.0 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 1.1 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 1.4 GO:0008354 germ cell migration(GO:0008354)
0.1 1.7 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.6 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.2 GO:0046222 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 0.9 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.4 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.3 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.5 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.2 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.5 GO:0046849 bone remodeling(GO:0046849)
0.1 1.0 GO:0031297 replication fork processing(GO:0031297)
0.0 1.7 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 1.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.7 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 1.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.8 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.8 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0003207 cardiac chamber formation(GO:0003207)
0.0 1.7 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 1.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.5 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 1.5 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 1.3 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.6 GO:0014029 neural crest formation(GO:0014029)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.4 GO:0051607 defense response to virus(GO:0051607)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.8 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 1.5 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.6 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.6 GO:0048599 oocyte development(GO:0048599)
0.0 0.4 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.2 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.6 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.0 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.4 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.5 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 2.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0043073 germ cell nucleus(GO:0043073)
0.1 1.0 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0071546 pi-body(GO:0071546)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.4 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 3.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.1 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 3.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 1.9 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.8 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 0.6 GO:0042806 fucose binding(GO:0042806)
0.2 1.0 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 0.9 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 1.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 1.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 1.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.5 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.1 2.1 GO:0032190 acrosin binding(GO:0032190)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.1 GO:0016936 galactoside binding(GO:0016936)
0.1 1.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 3.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.8 GO:0034584 piRNA binding(GO:0034584)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.5 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.8 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.1 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.5 GO:0008026 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 6.7 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0008236 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 2.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 4.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.3 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 3.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 4.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0019843 rRNA binding(GO:0019843)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.7 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.7 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.6 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.6 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 2.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation