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PRJNA207719: Tissue specific transcriptome profiling

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Results for fli1b

Z-value: 2.03

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Transcription factors associated with fli1b

Gene Symbol Gene ID Gene Info
fli1b
ENSDARG00000040080 Fli-1 proto-oncogene, ETS transcription factor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
fli1bdr11_v1_chr16_+_42018367_420183670.875.3e-02Click!

Activity profile of fli1b motif

Sorted Z-values of fli1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_38285671 2.38 ENSDART00000061432
ccl38a.4
chemokine (C-C motif) ligand 38, duplicate 4
chr22_+_5687615 1.65 ENSDART00000133241
ENSDART00000019854
ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr5_-_42272517 1.57 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr23_-_10175898 1.56 ENSDART00000146185
krt5
keratin 5
chr14_-_9128919 1.52 ENSDART00000108641
sh2d1ab
SH2 domain containing 1A duplicate b
chr14_-_40797117 1.18 ENSDART00000122369
elf1
E74-like ETS transcription factor 1
chr9_+_2499627 1.18 ENSDART00000160782
wipf1a
WAS/WASL interacting protein family, member 1a
chr19_-_19442983 1.11 ENSDART00000052649
sb:cb649
sb:cb649
chr16_-_51299061 1.10 ENSDART00000148677
serpinb1l4
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr6_-_29195642 1.08 ENSDART00000078625
dpt
dermatopontin
chr15_-_4528326 1.08 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr16_+_42018041 1.07 ENSDART00000134010
ENSDART00000102789
fli1b
Fli-1 proto-oncogene, ETS transcription factor b
chr7_+_39706004 1.05 ENSDART00000161856
ccl36.1
chemokine (C-C motif) ligand 36, duplicate 1
chr3_+_29510818 1.03 ENSDART00000055407
ENSDART00000193743
ENSDART00000123619
rac2
Rac family small GTPase 2
chr17_-_37395460 1.00 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr1_+_1904419 1.00 ENSDART00000142874
si:ch211-132g1.4
si:ch211-132g1.4
chr13_+_32144370 0.97 ENSDART00000020270
osr1
odd-skipped related transciption factor 1
chr25_+_34014523 0.93 ENSDART00000182856
anxa2a
annexin A2a
chr15_+_20239141 0.91 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr8_-_18010735 0.91 ENSDART00000125014
acot11b
acyl-CoA thioesterase 11b
chr15_+_17756113 0.90 ENSDART00000155197
si:ch211-213d14.2
si:ch211-213d14.2
chr5_-_26879302 0.90 ENSDART00000098571
ENSDART00000139086
zgc:64051
zgc:64051
chr8_-_7093507 0.88 ENSDART00000045669
si:dkey-222n6.2
si:dkey-222n6.2
chr11_+_8129536 0.88 ENSDART00000158112
ENSDART00000011183
prkacba
protein kinase, cAMP-dependent, catalytic, beta a
chr24_-_6078222 0.87 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr7_+_19482084 0.86 ENSDART00000173873
si:ch211-212k18.7
si:ch211-212k18.7
chr13_+_30696286 0.86 ENSDART00000192411
cxcl18a.1
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr1_-_18848955 0.86 ENSDART00000109294
ENSDART00000146410
zgc:195282
zgc:195282
chr16_-_39570832 0.85 ENSDART00000039832
tgfbr2b
transforming growth factor beta receptor 2b
chr2_+_48282590 0.84 ENSDART00000035338
lpar5a
lysophosphatidic acid receptor 5a
chr16_-_51288178 0.84 ENSDART00000079864
zgc:173729
zgc:173729
chr2_-_37862380 0.83 ENSDART00000186005
si:ch211-284o19.8
si:ch211-284o19.8
chr12_-_28983584 0.81 ENSDART00000112374
zgc:171713
zgc:171713
chr7_-_22981796 0.81 ENSDART00000167565
si:dkey-171c9.3
si:dkey-171c9.3
chr5_-_26834511 0.81 ENSDART00000136713
ENSDART00000192932
ENSDART00000113246
si:ch211-102c2.4
si:ch211-102c2.4
chr3_-_32603191 0.81 ENSDART00000150997
si:ch73-248e21.7
si:ch73-248e21.7
chr13_-_15986871 0.80 ENSDART00000189394
ikzf1
IKAROS family zinc finger 1 (Ikaros)
chr25_+_14109626 0.79 ENSDART00000109883
actc1c
actin, alpha, cardiac muscle 1c
chr21_-_34972872 0.79 ENSDART00000023838
lipia
lipase, member Ia
chr6_-_10233538 0.78 ENSDART00000182004
ENSDART00000149237
ENSDART00000148876
xirp2a
xin actin binding repeat containing 2a
chr9_+_54179306 0.78 ENSDART00000189829
tmsb4x
thymosin, beta 4 x
chr16_+_35401543 0.78 ENSDART00000171608
rab42b
RAB42, member RAS oncogene family
chr8_-_4586696 0.77 ENSDART00000143511
ENSDART00000134324
gp1bb
glycoprotein Ib (platelet), beta polypeptide
chr19_-_2231146 0.77 ENSDART00000181909
ENSDART00000043595
twist1a
twist family bHLH transcription factor 1a
chr8_-_31107537 0.75 ENSDART00000098925
vgll4l
vestigial like 4 like
chr18_-_16123222 0.74 ENSDART00000061189
sspn
sarcospan (Kras oncogene-associated gene)
chr21_-_28439596 0.74 ENSDART00000089980
ENSDART00000132844
rasgrp2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr7_+_20563305 0.73 ENSDART00000169661
si:dkey-19b23.10
si:dkey-19b23.10
chr7_-_48263516 0.73 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
rbpms2b
RNA binding protein with multiple splicing 2b
chr7_-_56606752 0.72 ENSDART00000138714
sult5a1
sulfotransferase family 5A, member 1
chr15_+_28410664 0.70 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
pitpnaa
phosphatidylinositol transfer protein, alpha a
chr4_-_22310956 0.69 ENSDART00000162585
hcls1
hematopoietic cell-specific Lyn substrate 1
chr8_-_17997845 0.68 ENSDART00000121660
acot11b
acyl-CoA thioesterase 11b
chr8_-_14209852 0.68 ENSDART00000005359
def6a
differentially expressed in FDCP 6a homolog (mouse)
chr5_+_37087583 0.67 ENSDART00000049900
tagln2
transgelin 2
chr19_-_15192840 0.67 ENSDART00000151337
phactr4a
phosphatase and actin regulator 4a
chr11_+_24314148 0.67 ENSDART00000171491
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr4_-_22311610 0.67 ENSDART00000137814
hcls1
hematopoietic cell-specific Lyn substrate 1
chr15_-_2652640 0.67 ENSDART00000146094
cldnf
claudin f
chr9_-_33877476 0.67 ENSDART00000150035
ENSDART00000088441
ENSDART00000183210
si:ch73-147f11.1
si:ch73-147f11.1
chr9_-_98982 0.67 ENSDART00000147882
lims2
LIM and senescent cell antigen-like domains 2
chr10_+_22775253 0.67 ENSDART00000190141
tmem88a
transmembrane protein 88 a
chr12_-_35830625 0.66 ENSDART00000180028
CU459056.1

chr16_-_10316359 0.66 ENSDART00000104025
flot1b
flotillin 1b
chr21_+_25765734 0.66 ENSDART00000021664
cldnb
claudin b
chr3_+_24655643 0.65 ENSDART00000126148
zmp:0000000912
zmp:0000000912
chr6_+_49881864 0.64 ENSDART00000075040
tubb1
tubulin, beta 1 class VI
chr9_+_14010823 0.64 ENSDART00000143837
si:ch211-67e16.3
si:ch211-67e16.3
chr16_-_26676685 0.63 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr11_-_11458208 0.63 ENSDART00000005485
krt93
keratin 93
chr16_-_51271962 0.63 ENSDART00000164021
ENSDART00000046420
serpinb1l1
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr12_+_22576404 0.63 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr11_+_24313931 0.62 ENSDART00000017599
ENSDART00000166045
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr8_+_25342896 0.62 ENSDART00000129032
CR847543.1

chr10_-_20650302 0.62 ENSDART00000142028
ENSDART00000064662
rassf2b
Ras association (RalGDS/AF-6) domain family member 2b
chr21_+_25198637 0.62 ENSDART00000164972
si:dkey-183i3.6
si:dkey-183i3.6
chr1_+_1915967 0.62 ENSDART00000131463
si:ch211-132g1.1
si:ch211-132g1.1
chr9_+_13985567 0.61 ENSDART00000102296
cd28
CD28 molecule
chr15_-_43284021 0.61 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_+_3127809 0.61 ENSDART00000185500
ckmt2a
creatine kinase, mitochondrial 2a (sarcomeric)
chr3_+_59899452 0.61 ENSDART00000064311
arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr5_-_34993242 0.60 ENSDART00000134516
ENSDART00000051295
btf3
basic transcription factor 3
chr9_-_31108285 0.60 ENSDART00000003193
gpr183a
G protein-coupled receptor 183a
chr19_+_43297546 0.60 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr15_-_551177 0.60 ENSDART00000066774
ENSDART00000154617
tagln
transgelin
chr7_+_17816006 0.59 ENSDART00000080834
eml3
echinoderm microtubule associated protein like 3
chr16_-_51253925 0.59 ENSDART00000050644
serpinb14
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr18_-_40856354 0.59 ENSDART00000098865
vaspb
vasodilator stimulated phosphoprotein b
chr17_-_12712776 0.59 ENSDART00000064511
il17a/f1
interleukin 17a/f1
chr19_+_48176745 0.59 ENSDART00000164963
prdm1b
PR domain containing 1b, with ZNF domain
chr9_-_34368842 0.59 ENSDART00000140349
cd247l
CD247 antigen like
chr7_-_26601307 0.58 ENSDART00000188934
plscr3b
phospholipid scramblase 3b
chr5_-_69716501 0.57 ENSDART00000158956
mob1a
MOB kinase activator 1A
chr21_-_25295087 0.57 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr20_+_25340814 0.56 ENSDART00000063028
ctgfa
connective tissue growth factor a
chr16_+_11818126 0.56 ENSDART00000145727
cxcr3.2
chemokine (C-X-C motif) receptor 3, tandem duplicate 2
chr7_+_11543999 0.56 ENSDART00000173676
il16
interleukin 16
chr19_-_12404590 0.55 ENSDART00000103703
ftr56
finTRIM family, member 56
chr13_-_45523026 0.55 ENSDART00000020663
rhd
Rh blood group, D antigen
chr17_-_7733037 0.55 ENSDART00000064657
stx11a
syntaxin 11a
chr19_-_15192638 0.55 ENSDART00000048151
phactr4a
phosphatase and actin regulator 4a
chr22_-_15280638 0.55 ENSDART00000063008
mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_+_43716607 0.55 ENSDART00000133199
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr7_+_19762595 0.54 ENSDART00000130347
si:dkey-9k7.3
si:dkey-9k7.3
chr3_+_27713610 0.54 ENSDART00000019004
arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr23_+_42813415 0.54 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr11_+_22109887 0.54 ENSDART00000122136
MDFI
si:dkey-91m3.1
chr13_-_13751017 0.53 ENSDART00000180182
ky
kyphoscoliosis peptidase
chr21_-_41025340 0.53 ENSDART00000148231
plac8l1
PLAC8-like 1
chr20_-_21672970 0.53 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr3_+_17939828 0.53 ENSDART00000185047
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr17_-_2039511 0.52 ENSDART00000160223
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr8_+_3379815 0.52 ENSDART00000155995
FUT9 (1 of many)
zgc:136963
chr8_-_19975087 0.52 ENSDART00000182220
lpxn
leupaxin
chr8_+_20398445 0.52 ENSDART00000134755
zap70
zeta chain of T cell receptor associated protein kinase 70
chr5_+_22133153 0.52 ENSDART00000016214
msna
moesin a
chr9_+_13999620 0.52 ENSDART00000143229
cd28l
cd28-like molecule
chr17_+_33453689 0.51 ENSDART00000156894
rin3
Ras and Rab interactor 3
chr24_-_31904924 0.51 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
si:ch73-78o10.1
chr1_-_29658721 0.51 ENSDART00000132063
si:dkey-1h24.6
si:dkey-1h24.6
chr13_-_42749916 0.51 ENSDART00000140019
capn2a
calpain 2, (m/II) large subunit a
chr22_-_17729778 0.51 ENSDART00000192132
si:ch73-63e15.2
si:ch73-63e15.2
chr21_+_30306369 0.50 ENSDART00000145050
ENSDART00000059420
lcp2a
lymphocyte cytosolic protein 2a
chr2_+_22495274 0.50 ENSDART00000167915
lrrc8da
leucine rich repeat containing 8 VRAC subunit Da
chr22_-_18164671 0.50 ENSDART00000014057
rfxank
regulatory factor X-associated ankyrin-containing protein
chr10_-_11012000 0.50 ENSDART00000132995
ak3
adenylate kinase 3
chr14_+_34501245 0.50 ENSDART00000131424
lcp2b
lymphocyte cytosolic protein 2b
chr18_+_49969568 0.50 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr1_-_52498146 0.50 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr5_+_30741730 0.50 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
ftr83
finTRIM family, member 83
chr9_-_30243393 0.50 ENSDART00000089539
si:dkey-100n23.3
si:dkey-100n23.3
chr10_+_9553935 0.49 ENSDART00000028855
si:ch211-243g18.2
si:ch211-243g18.2
chr3_+_17933132 0.49 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr8_+_48613040 0.49 ENSDART00000121432
nppa
natriuretic peptide A
chr16_-_23797570 0.49 ENSDART00000077834
rps27.2
ribosomal protein S27, isoform 2
chr13_-_37653840 0.48 ENSDART00000143806
si:dkey-188i13.11
si:dkey-188i13.11
chr22_-_31672566 0.48 ENSDART00000128247
lsm3
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr14_-_33613794 0.48 ENSDART00000010022
xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr22_-_17652112 0.48 ENSDART00000189205
hmha1b
histocompatibility (minor) HA-1 b
chr9_+_23772516 0.48 ENSDART00000183126
si:ch211-219a4.3
si:ch211-219a4.3
chr19_+_43579786 0.48 ENSDART00000138404
si:ch211-199g17.2
si:ch211-199g17.2
chr16_+_42018367 0.47 ENSDART00000058613
fli1b
Fli-1 proto-oncogene, ETS transcription factor b
chr21_+_22985078 0.47 ENSDART00000156491
lpar6b
lysophosphatidic acid receptor 6b
chr12_+_23892972 0.47 ENSDART00000152852
svila
supervillin a
chr25_+_35553542 0.47 ENSDART00000113723
spi1a
Spi-1 proto-oncogene a
chr14_-_897874 0.47 ENSDART00000167395
rgs14a
regulator of G protein signaling 14a
chr10_+_20113830 0.47 ENSDART00000139722
dmtn
dematin actin binding protein
chr16_-_9802449 0.47 ENSDART00000081208
tapbpl
TAP binding protein (tapasin)-like
chr1_-_45157243 0.46 ENSDART00000131882
mucms1
mucin, multiple PTS and SEA group, member 1
chr19_-_325584 0.46 ENSDART00000134266
gpd1c
glycerol-3-phosphate dehydrogenase 1c
chr7_+_18017756 0.46 ENSDART00000173717
ehbp1l1a
EH domain binding protein 1-like 1a
chr12_+_27536270 0.45 ENSDART00000133719
etv4
ets variant 4
chr5_+_46424437 0.45 ENSDART00000186511
vcana
versican a
chr25_-_16589461 0.45 ENSDART00000064204
cpa4
carboxypeptidase A4
chr6_-_55423220 0.44 ENSDART00000158929
ctsa
cathepsin A
chr8_-_25814263 0.44 ENSDART00000143397
taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_-_32659048 0.44 ENSDART00000093279
spi1b
Spi-1 proto-oncogene b
chr4_-_11064073 0.44 ENSDART00000150760
si:dkey-21h14.8
si:dkey-21h14.8
chr3_-_21382491 0.44 ENSDART00000016562
itga2b
integrin, alpha 2b
chr2_-_41964402 0.44 ENSDART00000131278
si:dkey-97a13.6
si:dkey-97a13.6
chr7_-_32659345 0.44 ENSDART00000126831
ENSDART00000036729
spi1b
Spi-1 proto-oncogene b
chr25_-_16600811 0.44 ENSDART00000011397
cpa2
carboxypeptidase A2 (pancreatic)
chr3_+_24612191 0.43 ENSDART00000190998
zgc:171506
zgc:171506
chr24_-_2423791 0.43 ENSDART00000190402
rreb1a
ras responsive element binding protein 1a
chr21_+_30794351 0.43 ENSDART00000139486
zgc:158225
zgc:158225
chr6_-_8480815 0.43 ENSDART00000162300
rasal3
RAS protein activator like 3
chr2_-_25140022 0.42 ENSDART00000134543
nceh1a
neutral cholesterol ester hydrolase 1a
chr9_-_9419704 0.42 ENSDART00000138996
si:ch211-214p13.9
si:ch211-214p13.9
chr15_+_17251191 0.42 ENSDART00000156587
si:ch73-223p23.2
si:ch73-223p23.2
chr23_+_44049509 0.42 ENSDART00000102003
txk
TXK tyrosine kinase
chr21_-_11632403 0.42 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
cast
calpastatin
chr1_+_33558555 0.42 ENSDART00000018472
chmp2bb
charged multivesicular body protein 2Bb
chr21_+_261490 0.42 ENSDART00000177919
jak2a
Janus kinase 2a
chr3_+_24641489 0.42 ENSDART00000055590
ENSDART00000186635
zgc:113411
zgc:113411
chr18_+_38288877 0.41 ENSDART00000134247
lmo2
LIM domain only 2 (rhombotin-like 1)
chr14_+_23709543 0.41 ENSDART00000136909
gnpda1
glucosamine-6-phosphate deaminase 1
chr1_-_8653385 0.41 ENSDART00000193041
actb1
actin, beta 1
chr10_+_7798087 0.41 ENSDART00000141824
sftpba
surfactant protein Ba
chr22_-_18164835 0.41 ENSDART00000143189
rfxank
regulatory factor X-associated ankyrin-containing protein
chr12_+_20552190 0.41 ENSDART00000113224
gna13a
guanine nucleotide binding protein (G protein), alpha 13a
chr9_+_21165484 0.41 ENSDART00000177286
si:rp71-68n21.9
si:rp71-68n21.9
chr20_+_15600167 0.41 ENSDART00000171991
faslg
Fas ligand (TNF superfamily, member 6)
chr13_-_37189560 0.41 ENSDART00000134789
si:dkeyp-77c8.2
si:dkeyp-77c8.2
chr9_-_51563575 0.40 ENSDART00000167034
ENSDART00000148918
tank
TRAF family member-associated NFKB activator
chr3_+_22377312 0.40 ENSDART00000155597
arhgap27l
Rho GTPase activating protein 27, like
chr1_+_1896737 0.40 ENSDART00000152442
si:ch211-132g1.6
si:ch211-132g1.6
chr2_+_13069168 0.40 ENSDART00000192832
prkag2b
protein kinase, AMP-activated, gamma 2 non-catalytic subunit b
chr13_-_7031033 0.40 ENSDART00000193211
CABZ01061524.1

chr3_+_3545825 0.40 ENSDART00000109060
CR589947.1

chr25_-_21031007 0.40 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr1_-_52497834 0.40 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr5_+_42136359 0.39 ENSDART00000083731
trpv1
transient receptor potential cation channel, subfamily V, member 1
chr14_-_34059681 0.39 ENSDART00000003993
itk
IL2 inducible T cell kinase
chr21_+_29077509 0.39 ENSDART00000128561
ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr23_+_7505943 0.39 ENSDART00000135787
hck
HCK proto-oncogene, Src family tyrosine kinase
chr10_+_36197968 0.39 ENSDART00000114102
COA4
si:ch211-215a9.5
chr13_+_24402406 0.39 ENSDART00000043002
rab1ab
RAB1A, member RAS oncogene family b
chr18_-_20869175 0.38 ENSDART00000090079
synm
synemin, intermediate filament protein
chr24_-_40726073 0.38 ENSDART00000168100
smyhc2
slow myosin heavy chain 2
chr18_+_27598755 0.38 ENSDART00000193808
cd82b
CD82 molecule b

Network of associatons between targets according to the STRING database.

First level regulatory network of fli1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.3 1.0 GO:0048389 intermediate mesoderm development(GO:0048389)
0.3 1.4 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.3 0.8 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.3 1.3 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.7 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.2 1.0 GO:0072672 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.2 0.6 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.2 0.6 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.2 0.9 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 1.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 0.5 GO:1905072 cardiac jelly development(GO:1905072)
0.2 0.5 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.1 0.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.4 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.1 0.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.4 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.5 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 1.8 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 0.8 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.3 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.5 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.3 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.7 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 3.4 GO:0002548 monocyte chemotaxis(GO:0002548)
0.1 0.3 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.3 GO:0045123 cellular extravasation(GO:0045123)
0.1 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.3 GO:0002637 regulation of immunoglobulin production(GO:0002637) positive regulation of immunoglobulin production(GO:0002639)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.1 0.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.5 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.3 GO:0045822 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.1 0.7 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.4 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.4 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.2 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.3 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.3 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.1 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 1.1 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.8 GO:0035108 limb morphogenesis(GO:0035108)
0.0 0.8 GO:0050926 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.6 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 1.1 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 1.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.0 0.5 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 2.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.6 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.9 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.6 GO:0001843 neural tube closure(GO:0001843)
0.0 0.1 GO:1990120 lymphoid progenitor cell differentiation(GO:0002320) messenger ribonucleoprotein complex assembly(GO:1990120)
0.0 0.5 GO:0090050 positive regulation of blood vessel endothelial cell migration(GO:0043536) regulation of cell migration involved in sprouting angiogenesis(GO:0090049) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.5 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.3 GO:0031179 peptide modification(GO:0031179)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0021755 eurydendroid cell differentiation(GO:0021755)
0.0 0.3 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 1.3 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.9 GO:0030834 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.7 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.2 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.4 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0061055 myotome development(GO:0061055)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.7 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.2 GO:0001541 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 1.5 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 1.8 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.4 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.2 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.4 GO:0098703 response to heat(GO:0009408) calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.5 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.2 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.7 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.0 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.0 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0071962 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.4 GO:0002761 regulation of myeloid leukocyte differentiation(GO:0002761)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 2.2 GO:0030041 actin filament polymerization(GO:0030041)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.0 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0003313 heart rudiment development(GO:0003313)
0.0 0.8 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.3 GO:0001841 neural tube formation(GO:0001841)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.0 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 1.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.2 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.4 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.9 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0045095 keratin filament(GO:0045095)
0.2 1.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 0.6 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.2 0.7 GO:0016600 flotillin complex(GO:0016600)
0.1 0.7 GO:0097433 dense body(GO:0097433)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.7 GO:0031526 brush border membrane(GO:0031526)
0.1 0.2 GO:0034709 methylosome(GO:0034709)
0.1 0.2 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.1 0.2 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.4 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 4.2 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.6 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.0 GO:1990879 CST complex(GO:1990879)
0.0 0.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0070449 elongin complex(GO:0070449)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.0 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 0.8 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 1.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 0.7 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 0.6 GO:0019767 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.2 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.8 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 0.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.7 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 1.2 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.5 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 3.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 1.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.4 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.2 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 0.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.9 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.2 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 0.2 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.6 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.4 GO:0031779 melanocortin receptor binding(GO:0031779)
0.1 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 4.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.3 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.2 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.1 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.0 1.1 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 7.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.0 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase