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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxc1a+foxc1b

Z-value: 1.25

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Transcription factors associated with foxc1a+foxc1b

Gene Symbol Gene ID Gene Info
foxc1b
ENSDARG00000055398 forkhead box C1b
foxc1a
ENSDARG00000091481 forkhead box C1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxc1adr11_v1_chr2_-_689047_689047-0.227.3e-01Click!
foxc1bdr11_v1_chr20_+_26702377_26702377-0.069.2e-01Click!

Activity profile of foxc1a+foxc1b motif

Sorted Z-values of foxc1a+foxc1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_11200550 1.20 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr1_-_45177373 1.12 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr22_+_20720808 0.97 ENSDART00000171321
si:dkey-211f22.5
si:dkey-211f22.5
chr1_+_7540978 0.85 ENSDART00000147770
mylz3
myosin, light polypeptide 3, skeletal muscle
chr12_-_26064105 0.82 ENSDART00000168825
ldb3b
LIM domain binding 3b
chr12_-_26064480 0.80 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
ldb3b
LIM domain binding 3b
chr18_-_16792561 0.79 ENSDART00000145546
ampd3b
adenosine monophosphate deaminase 3b
chr20_-_27311675 0.75 ENSDART00000026088
ENSDART00000148361
asb2a.1
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr24_-_40726073 0.70 ENSDART00000168100
smyhc2
slow myosin heavy chain 2
chr12_+_20641471 0.67 ENSDART00000133654
calcoco2
calcium binding and coiled-coil domain 2
chr16_-_12723324 0.62 ENSDART00000131915
sbk3
SH3 domain binding kinase family, member 3
chr19_-_10730488 0.61 ENSDART00000126033
slc9a3.1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 1
chr21_-_22928214 0.60 ENSDART00000182760
dub
duboraya
chr1_-_14332283 0.60 ENSDART00000090025
wfs1a
Wolfram syndrome 1a (wolframin)
chr10_+_44956660 0.57 ENSDART00000169225
ENSDART00000189298
il1b
interleukin 1, beta
chr11_-_29946927 0.56 ENSDART00000165182
zgc:113276
zgc:113276
chr16_-_13992646 0.56 ENSDART00000139623
si:dkey-85k15.6
si:dkey-85k15.6
chr21_+_6556635 0.54 ENSDART00000139598
col5a1
procollagen, type V, alpha 1
chr6_+_40629066 0.50 ENSDART00000103757
slc6a11a
solute carrier family 6 (neurotransmitter transporter), member 11a
chr6_-_10828880 0.49 ENSDART00000131458
ENSDART00000020261
chrna1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr16_-_24815091 0.48 ENSDART00000154269
ENSDART00000131025
kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr16_+_7662609 0.45 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
bves
blood vessel epicardial substance
chr18_+_16986903 0.43 ENSDART00000142088
si:ch211-218c6.8
si:ch211-218c6.8
chr9_-_21918963 0.43 ENSDART00000090782
lmo7a
LIM domain 7a
chr23_-_16737161 0.41 ENSDART00000132573
si:ch211-224l10.4
si:ch211-224l10.4
chr17_+_45404758 0.41 ENSDART00000147557
tagapa
T cell activation RhoGTPase activating protein a
chr7_-_38790341 0.41 ENSDART00000159884
si:dkey-23n7.10
si:dkey-23n7.10
chr13_+_28417297 0.41 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr1_-_45146834 0.41 ENSDART00000144997
si:ch211-239f4.6
si:ch211-239f4.6
chr11_+_18183220 0.41 ENSDART00000113468
LO018315.10

chr25_+_20216159 0.38 ENSDART00000048642
tnnt2d
troponin T2d, cardiac
chr6_-_51771634 0.38 ENSDART00000073847
blcap
bladder cancer associated protein
chr10_+_15107886 0.37 ENSDART00000188047
ENSDART00000164095
scpp8
secretory calcium-binding phosphoprotein 8
chr22_-_22147375 0.36 ENSDART00000149304
cdc34a
cell division cycle 34 homolog (S. cerevisiae) a
chr3_-_18030938 0.36 ENSDART00000013540
si:ch73-141c7.1
si:ch73-141c7.1
chr25_+_26798673 0.35 ENSDART00000157235
ca12
carbonic anhydrase XII
chr1_+_18550864 0.34 ENSDART00000142515
si:dkey-192k22.2
si:dkey-192k22.2
chr23_+_2185397 0.34 ENSDART00000109373
c1qtnf7
C1q and TNF related 7
chr7_-_18691637 0.34 ENSDART00000183715
si:ch211-119e14.9
si:ch211-119e14.9
chr7_-_16598212 0.34 ENSDART00000128488
e2f8
E2F transcription factor 8
chr4_-_13502549 0.34 ENSDART00000140366
si:ch211-266a5.12
si:ch211-266a5.12
chr2_-_22152797 0.34 ENSDART00000145188
cyp7a1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr24_-_25428176 0.33 ENSDART00000090010
phex
phosphate regulating endopeptidase homolog, X-linked
chr16_-_42004544 0.33 ENSDART00000034544
caspa
caspase a
chr1_-_23274393 0.33 ENSDART00000147800
ENSDART00000130277
ENSDART00000054340
ENSDART00000054338
rpl9
ribosomal protein L9
chr22_-_23000815 0.33 ENSDART00000137111
ptprc
protein tyrosine phosphatase, receptor type, C
chr5_+_39087364 0.32 ENSDART00000004286
anxa3a
annexin A3a
chr16_-_13818061 0.32 ENSDART00000132982
ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr14_+_30285613 0.32 ENSDART00000173090
mtus1a
microtubule associated tumor suppressor 1a
chr3_+_29641181 0.32 ENSDART00000151517
eif3d
eukaryotic translation initiation factor 3, subunit D
chr20_-_35578435 0.30 ENSDART00000142444
adgrf6
adhesion G protein-coupled receptor F6
chr3_+_59411956 0.30 ENSDART00000166982
sec14l1
SEC14-like lipid binding 1
chr16_-_5721386 0.29 ENSDART00000136655
ndufa3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr5_-_4219741 0.29 ENSDART00000100093
si:ch211-283g2.2
si:ch211-283g2.2
chr7_+_19482877 0.29 ENSDART00000077868
si:ch211-212k18.7
si:ch211-212k18.7
chr9_+_15893093 0.28 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
si:dkey-14o1.20
chr3_-_43770876 0.28 ENSDART00000160162
zgc:92162
zgc:92162
chr22_+_34616151 0.28 ENSDART00000155399
ENSDART00000104705
si:ch1073-214b20.2
si:ch1073-214b20.2
chr23_-_36316352 0.28 ENSDART00000014840
nfe2
nuclear factor, erythroid 2
chr9_-_24244383 0.27 ENSDART00000182407
cavin2a
caveolae associated protein 2a
chr15_+_15456910 0.27 ENSDART00000155708
zgc:174895
zgc:174895
chr3_+_12784460 0.27 ENSDART00000168382
cyp2k8
cytochrome P450, family 2, subfamily K, polypeptide 8
chr6_-_8480815 0.27 ENSDART00000162300
rasal3
RAS protein activator like 3
chr4_-_11132617 0.27 ENSDART00000150250
si:dkey-21h14.9
si:dkey-21h14.9
chr14_-_2602445 0.25 ENSDART00000166910
etf1a
eukaryotic translation termination factor 1a
chr23_-_42752387 0.25 ENSDART00000149781
si:ch73-217n20.1
si:ch73-217n20.1
chr1_+_45056371 0.25 ENSDART00000073689
ENSDART00000167309
btr01
bloodthirsty-related gene family, member 1
chr20_+_38276690 0.25 ENSDART00000061437
ccl38.6
chemokine (C-C motif) ligand 38, duplicate 6
chr5_-_65000312 0.23 ENSDART00000192893
ANXA1 (1 of many)
zgc:110283
chr10_+_22034477 0.23 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
npm1a
nucleophosmin 1a
chr20_+_38458084 0.23 ENSDART00000020153
ENSDART00000135912
coq8a
coenzyme Q8A
chr15_+_37973197 0.23 ENSDART00000156661
si:dkey-238d18.9
si:dkey-238d18.9
chr19_+_7930004 0.23 ENSDART00000160410
si:dkey-266f7.4
si:dkey-266f7.4
chr17_-_53439866 0.23 ENSDART00000154826
mycbp
c-myc binding protein
chr20_+_10723292 0.23 ENSDART00000152805
si:ch211-182e10.4
si:ch211-182e10.4
chr19_+_7929704 0.23 ENSDART00000147015
si:dkey-266f7.4
si:dkey-266f7.4
chr8_-_20243389 0.22 ENSDART00000184904
acer1
alkaline ceramidase 1
chr2_-_2642476 0.22 ENSDART00000124032
serbp1b
SERPINE1 mRNA binding protein 1b
chr19_+_4051695 0.22 ENSDART00000166368
btr24
bloodthirsty-related gene family, member 24
chr22_-_10486477 0.22 ENSDART00000184366
aspn
asporin (LRR class 1)
chr2_-_27473645 0.22 ENSDART00000186152
CU469530.2

chr2_+_49644803 0.21 ENSDART00000160342
si:ch211-209f23.7
si:ch211-209f23.7
chr9_+_24192370 0.21 ENSDART00000003482
stk17b
serine/threonine kinase 17b (apoptosis-inducing)
chr4_-_4387012 0.21 ENSDART00000191836
CU468826.3
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr7_+_19483277 0.21 ENSDART00000173750
si:ch211-212k18.7
si:ch211-212k18.7
chr1_-_56717813 0.21 ENSDART00000159196
FO681314.1

chr22_+_6198742 0.20 ENSDART00000132889
si:dkey-19a16.11
si:dkey-19a16.11
chr15_-_1590858 0.20 ENSDART00000081875
nnr
nanor
chr13_-_301309 0.20 ENSDART00000131747
chs1
chitin synthase 1
chr12_-_22524388 0.20 ENSDART00000020942
shbg
sex hormone-binding globulin
chr21_-_17290941 0.20 ENSDART00000147993
gfi1b
growth factor independent 1B transcription repressor
chr6_-_39275793 0.20 ENSDART00000180477
ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr22_-_10487490 0.20 ENSDART00000064798
aspn
asporin (LRR class 1)
chr8_-_36370552 0.20 ENSDART00000097932
ENSDART00000148323
si:busm1-104n07.3
si:busm1-104n07.3
chr23_+_24926407 0.20 ENSDART00000137486
klhl21
kelch-like family member 21
chr6_+_33931740 0.19 ENSDART00000130492
ENSDART00000151213
orc1
origin recognition complex, subunit 1
chr23_+_16910071 0.19 ENSDART00000104793
si:dkey-147f3.8
si:dkey-147f3.8
chr9_+_13985567 0.19 ENSDART00000102296
cd28
CD28 molecule
chr8_+_19514294 0.18 ENSDART00000170622
si:ch73-281k2.5
si:ch73-281k2.5
chr18_+_50669456 0.18 ENSDART00000163005
si:dkey-151j17.4
si:dkey-151j17.4
chr14_-_29858883 0.17 ENSDART00000141034
sorbs2b
sorbin and SH3 domain containing 2b
chr7_-_24838367 0.17 ENSDART00000139455
ENSDART00000012483
ENSDART00000131530
fam113
family with sequence similarity 113
chr13_+_21600946 0.17 ENSDART00000144045
sh2d4ba
SH2 domain containing 4Ba
chr17_-_33415740 0.17 ENSDART00000135218
ccdc28a
coiled-coil domain containing 28A
chr25_+_31958911 0.17 ENSDART00000191394
ENSDART00000090727
ENSDART00000185893
duox
dual oxidase
chr15_+_47903864 0.16 ENSDART00000063835
otx5
orthodenticle homolog 5
chr9_-_23994225 0.16 ENSDART00000140346
col6a3
collagen, type VI, alpha 3
chr19_-_33370271 0.16 ENSDART00000132628
nkd3l
naked cuticle homolog 3, like
chr15_-_38009344 0.16 ENSDART00000157094
si:dkey-238d18.6
si:dkey-238d18.6
chr21_-_39931285 0.16 ENSDART00000180010
ENSDART00000024407
tmigd1
transmembrane and immunoglobulin domain containing 1
chr14_+_15484544 0.16 ENSDART00000188649
CR382326.1

chr24_+_9372292 0.16 ENSDART00000082422
ENSDART00000191127
ENSDART00000180510
si:ch211-285f17.1
si:ch211-285f17.1
chr5_-_57624425 0.16 ENSDART00000167892
zgc:193711
zgc:193711
chr17_+_21477892 0.16 ENSDART00000155309
pla2g4f.2
phospholipase A2, group IVF, tandem duplicate 2
chr5_+_37890521 0.16 ENSDART00000140207
tmprss4b
transmembrane protease, serine 4b
chr14_-_46310204 0.16 ENSDART00000188713
ENSDART00000184930
crybb1l1
crystallin, beta B1, like 1
chr9_+_12890161 0.16 ENSDART00000146477
si:ch211-167j6.4
si:ch211-167j6.4
chr25_+_19238175 0.16 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
ppip5k1b
diphosphoinositol pentakisphosphate kinase 1b
chr9_+_18576047 0.16 ENSDART00000145174
lacc1
laccase (multicopper oxidoreductase) domain containing 1
chr7_-_31321027 0.15 ENSDART00000186878
CR356242.1

chr15_-_20468302 0.15 ENSDART00000018514
dlc
deltaC
chr20_+_36812368 0.15 ENSDART00000062931
abracl
ABRA C-terminal like
chr9_+_51180508 0.15 ENSDART00000138990
ifih1
interferon induced with helicase C domain 1
chr17_-_17764801 0.15 ENSDART00000155261
slirp
SRA stem-loop interacting RNA binding protein
chr3_-_34586403 0.15 ENSDART00000151515
sept9a
septin 9a
chr2_-_43635777 0.15 ENSDART00000148633
itgb1b.1
integrin, beta 1b.1
chr12_-_9438227 0.15 ENSDART00000003932
erbb2
erb-b2 receptor tyrosine kinase 2
chr4_-_17353100 0.15 ENSDART00000134467
ENSDART00000189019
parpbp
PARP1 binding protein
chr22_+_26793389 0.15 ENSDART00000165381
pimr69
Pim proto-oncogene, serine/threonine kinase, related 69
chr7_+_49695904 0.14 ENSDART00000183550
ENSDART00000126991
ascl1b
achaete-scute family bHLH transcription factor 1b
chr1_-_23293261 0.14 ENSDART00000122648
ugdh
UDP-glucose 6-dehydrogenase
chr9_+_17309195 0.14 ENSDART00000048548
scel
sciellin
chr8_-_13419049 0.14 ENSDART00000133656
pimr101
Pim proto-oncogene, serine/threonine kinase, related 101
chr22_-_20289948 0.14 ENSDART00000132951
si:dkey-110c1.10
si:dkey-110c1.10
chr4_+_12358822 0.14 ENSDART00000172557
ENSDART00000150627
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr8_-_13471916 0.13 ENSDART00000146558
pimr105
Pim proto-oncogene, serine/threonine kinase, related 105
chr7_-_17591007 0.13 ENSDART00000171023
CU672228.1

chr13_+_21601149 0.13 ENSDART00000179369
sh2d4ba
SH2 domain containing 4Ba
chr22_-_8860869 0.13 ENSDART00000166188
CABZ01046427.2

chr2_-_51500957 0.13 ENSDART00000172481
pigrl3.5
polymeric immunoglobulin receptor-like 3.5
chr15_-_37921998 0.13 ENSDART00000193597
ENSDART00000181443
ENSDART00000168790
si:dkey-238d18.5
si:dkey-238d18.5
chr6_+_18441331 0.13 ENSDART00000171005
si:dkey-31g6.4
si:dkey-31g6.4
chr18_+_15706160 0.13 ENSDART00000131524
si:ch211-264e16.1
si:ch211-264e16.1
chr8_-_18200003 0.12 ENSDART00000080014
rps8b
ribosomal protein S8b
chr1_-_2061419 0.12 ENSDART00000058878
oxgr1a.3
oxoglutarate (alpha-ketoglutarate) receptor 1a, tandem duplicate 3
chr1_+_40158146 0.12 ENSDART00000145694
si:ch211-113e8.9
si:ch211-113e8.9
chr25_-_35101673 0.12 ENSDART00000140864
zgc:162611
zgc:162611
chr11_+_16138065 0.12 ENSDART00000188616
pimr204
Pim proto-oncogene, serine/threonine kinase, related 204
chr4_+_12333168 0.12 ENSDART00000172455
ENSDART00000146166
pimr214
pimr171
Pim proto-oncogene, serine/threonine kinase, related 214
Pim proto-oncogene, serine/threonine kinase, related 171
chr12_+_29236274 0.12 ENSDART00000006505
mxtx2
mix-type homeobox gene 2
chr15_-_3976035 0.12 ENSDART00000168061
si:ch73-309g22.1
si:ch73-309g22.1
chr24_-_36270855 0.12 ENSDART00000154858
si:ch211-40k21.5
si:ch211-40k21.5
chr7_-_57509447 0.12 ENSDART00000051973
ENSDART00000147036
sirt3
sirtuin 3
chr20_+_51479263 0.12 ENSDART00000148798
tlr5a
toll-like receptor 5a
chr2_-_37537887 0.12 ENSDART00000143496
ENSDART00000025841
arhgef18a
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr8_-_46525092 0.12 ENSDART00000030482
sult1st2
sulfotransferase family 1, cytosolic sulfotransferase 2
chr9_-_7089303 0.11 ENSDART00000146609
coa5
cytochrome C oxidase assembly factor 5
chr4_+_12342173 0.11 ENSDART00000161518
pimr214
Pim proto-oncogene, serine/threonine kinase, related 214
chr14_-_38865800 0.11 ENSDART00000173047
gsr
glutathione reductase
chr11_+_42765963 0.11 ENSDART00000156080
ENSDART00000179888
tdrd3
tudor domain containing 3
chr5_-_23705828 0.11 ENSDART00000189419
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr7_-_16214889 0.11 ENSDART00000076318
ENSDART00000173946
btr06
bloodthirsty-related gene family, member 6
chr24_-_12958668 0.11 ENSDART00000178982
FITM1 (1 of many)
Danio rerio fat storage inducing transmembrane protein 1 (LOC792443), mRNA.
chr23_-_44819100 0.11 ENSDART00000076373
st8sia7.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 7.1
chr15_-_37921702 0.10 ENSDART00000153491
si:dkey-238d18.5
si:dkey-238d18.5
chr24_-_36271352 0.10 ENSDART00000153682
ENSDART00000155892
si:ch211-40k21.5
si:ch211-40k21.5
chr12_-_22355430 0.10 ENSDART00000153296
ENSDART00000056919
ENSDART00000159036
nsfb
N-ethylmaleimide-sensitive factor b
chr1_-_25679339 0.10 ENSDART00000161703
ENSDART00000054230
fgg
fibrinogen gamma chain
chr17_+_12265095 0.10 ENSDART00000153812
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr25_-_31953516 0.10 ENSDART00000110180
duox2
dual oxidase 2
chr12_+_695619 0.10 ENSDART00000161691
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr23_-_22113455 0.10 ENSDART00000142474
phc2a
polyhomeotic homolog 2a (Drosophila)
chr3_-_34052882 0.10 ENSDART00000151463
ighv11-1
immunoglobulin heavy variable 11-1
chr6_-_34008827 0.10 ENSDART00000191183
ENSDART00000003701
ENSDART00000192502
tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr16_-_31974482 0.09 ENSDART00000189073
styk1
serine/threonine/tyrosine kinase 1
chr10_+_8554929 0.09 ENSDART00000190849
tbc1d10ab
TBC1 domain family, member 10Ab
chr18_+_808911 0.09 ENSDART00000172518
cox5ab
cytochrome c oxidase subunit Vab
chr4_-_67980261 0.09 ENSDART00000182305
si:ch211-223k15.1
si:ch211-223k15.1
chr15_-_36347858 0.09 ENSDART00000155274
ENSDART00000157936
si:dkey-23k10.2
si:dkey-23k10.2
chr16_+_33938227 0.09 ENSDART00000166254
gpn2
GPN-loop GTPase 2
chr11_+_17984354 0.09 ENSDART00000179986
rpusd4
RNA pseudouridylate synthase domain containing 4
chr12_-_20665164 0.09 ENSDART00000105352
gip
gastric inhibitory polypeptide
chr7_+_53254234 0.09 ENSDART00000169830
trip4
thyroid hormone receptor interactor 4
chr18_+_25752592 0.09 ENSDART00000111767
si:ch211-39k3.2
si:ch211-39k3.2
chr7_-_32981559 0.09 ENSDART00000175614
pkp3b
plakophilin 3b
chr13_+_36680564 0.09 ENSDART00000136030
ENSDART00000006923
atp5s
ATP synthase, H+ transporting, mitochondrial F0 complex subunit s
chr21_+_18274825 0.08 ENSDART00000144322
ENSDART00000147768
wdr5
WD repeat domain 5
chr20_-_46817223 0.08 ENSDART00000100336
esrrgb
estrogen-related receptor gamma b
chr16_-_4203022 0.08 ENSDART00000018686
rrp15
ribosomal RNA processing 15 homolog
chr13_-_36680531 0.08 ENSDART00000085298
l2hgdh
L-2-hydroxyglutarate dehydrogenase
chr7_+_9981757 0.07 ENSDART00000113429
ENSDART00000173233
adamts17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr10_+_38512270 0.07 ENSDART00000109752
serpinh1a
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr2_-_24554416 0.07 ENSDART00000052061
cnn2
calponin 2
chr2_-_11101329 0.07 ENSDART00000164416
lrrc53
leucine rich repeat containing 53
chr6_-_40448416 0.07 ENSDART00000187019
ENSDART00000179469
tatdn2
TatD DNase domain containing 2
chr3_+_25825043 0.07 ENSDART00000153749
pik3r6b
phosphoinositide-3-kinase, regulatory subunit 6b
chr21_-_30111134 0.07 ENSDART00000014223
slc23a1
solute carrier family 23 (ascorbic acid transporter), member 1
chr1_-_35113974 0.07 ENSDART00000192811
ENSDART00000167461
BX897691.1

chr13_+_8696825 0.07 ENSDART00000109059
ttc7a
tetratricopeptide repeat domain 7A
chr10_+_28160265 0.07 ENSDART00000022484
rnft1
ring finger protein, transmembrane 1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxc1a+foxc1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.6 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.4 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.1 0.3 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.1 0.5 GO:0086009 membrane repolarization(GO:0086009)
0.1 0.8 GO:0032264 IMP salvage(GO:0032264)
0.1 0.3 GO:0008206 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.1 0.6 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.2 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.2 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.1 GO:0048939 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.0 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.2 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.2 GO:0032728 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.0 0.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.1 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.3 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0032475 otolith formation(GO:0032475)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.6 GO:0031526 brush border membrane(GO:0031526)
0.1 1.2 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.3 GO:0030428 cell septum(GO:0030428)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.3 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.1 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.8 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.6 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.3 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.4 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.1 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.0 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex