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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxd2_foxd5

Z-value: 1.94

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Transcription factors associated with foxd2_foxd5

Gene Symbol Gene ID Gene Info
foxd2
ENSDARG00000058133 forkhead box D2
foxd5
ENSDARG00000042485 forkhead box D5
foxd5
ENSDARG00000109712 forkhead box D5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxd2dr11_v1_chr8_+_19674369_19674369-0.711.8e-01Click!
foxd5dr11_v1_chr8_+_30452945_30452945-0.701.9e-01Click!

Activity profile of foxd2_foxd5 motif

Sorted Z-values of foxd2_foxd5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_34127005 2.89 ENSDART00000167384
ENSDART00000078065
f5
coagulation factor V
chr14_+_21107032 2.66 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr4_-_25215968 2.37 ENSDART00000066932
ENSDART00000066933
itih2
inter-alpha-trypsin inhibitor heavy chain 2
chr14_+_11458044 2.31 ENSDART00000186425
si:ch211-153b23.5
si:ch211-153b23.5
chr18_-_46354269 2.15 ENSDART00000010813
foxa3
forkhead box A3
chr14_+_11457500 2.13 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr12_-_22524388 2.02 ENSDART00000020942
shbg
sex hormone-binding globulin
chr21_+_40092301 1.90 ENSDART00000145150
serpinf2a
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr18_-_6803424 1.77 ENSDART00000142647
si:dkey-266m15.5
si:dkey-266m15.5
chr13_-_4707018 1.69 ENSDART00000128422
oit3
oncoprotein induced transcript 3
chr9_-_33063083 1.37 ENSDART00000048550
si:ch211-125e6.5
si:ch211-125e6.5
chr12_+_46543572 1.37 ENSDART00000167510
hid1b
HID1 domain containing b
chr7_+_27603211 1.37 ENSDART00000148782
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr3_-_45848257 1.35 ENSDART00000147198
igfals
insulin-like growth factor binding protein, acid labile subunit
chr3_-_45848043 1.32 ENSDART00000055132
igfals
insulin-like growth factor binding protein, acid labile subunit
chr21_+_27416284 1.27 ENSDART00000077593
ENSDART00000108763
cfb
complement factor B
chr20_-_6532462 1.21 ENSDART00000054653
mcm3l
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr6_-_55864687 1.20 ENSDART00000160991
cyp24a1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr22_-_23668356 1.18 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
cfh
complement factor H
chr3_-_15081874 1.17 ENSDART00000192532
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr16_+_23975930 1.14 ENSDART00000147858
ENSDART00000144347
ENSDART00000115270
apoc4
apolipoprotein C-IV
chr5_+_26795465 1.14 ENSDART00000053001
tcn2
transcobalamin II
chr8_-_13013123 1.12 ENSDART00000147802
dennd2da
DENN/MADD domain containing 2Da
chr2_-_40191603 1.11 ENSDART00000180691
si:ch211-122l24.6
si:ch211-122l24.6
chr14_-_4120636 1.05 ENSDART00000059230
irf2
interferon regulatory factor 2
chr3_-_50139860 1.04 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr14_-_4121052 1.04 ENSDART00000167074
irf2
interferon regulatory factor 2
chr9_-_16109001 1.01 ENSDART00000053473
upp2
uridine phosphorylase 2
chr16_+_23976227 0.98 ENSDART00000193013
apoc4
apolipoprotein C-IV
chr15_-_37829160 0.97 ENSDART00000099425
ctrl
chymotrypsin-like
chr18_-_17077596 0.96 ENSDART00000111821
il17c
interleukin 17c
chr2_+_27855102 0.95 ENSDART00000150330
buc
bucky ball
chr1_-_30473422 0.95 ENSDART00000164202
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr18_-_17077419 0.94 ENSDART00000148714
il17c
interleukin 17c
chr7_+_53156810 0.93 ENSDART00000189816
cdh29
cadherin 29
chr16_-_13388821 0.92 ENSDART00000144062
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr6_-_24053404 0.91 ENSDART00000168511
si:dkey-44g17.6
si:dkey-44g17.6
chr20_-_49889111 0.89 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr22_-_38819603 0.88 ENSDART00000104437
si:ch211-262h13.5
si:ch211-262h13.5
chr20_-_30369598 0.87 ENSDART00000144549
allc
allantoicase
chr3_+_36424055 0.83 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr3_-_29506960 0.82 ENSDART00000141720
cyth4a
cytohesin 4a
chr16_-_38629208 0.81 ENSDART00000126705
eif3ea
eukaryotic translation initiation factor 3, subunit E, a
chr2_-_127945 0.81 ENSDART00000056453
igfbp1b
insulin-like growth factor binding protein 1b
chr22_-_17595310 0.79 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr22_+_11756040 0.78 ENSDART00000105808
krt97
keratin 97
chr7_+_21180747 0.77 ENSDART00000185543
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr9_-_33081781 0.77 ENSDART00000165748
zgc:172053
zgc:172053
chr15_+_45563656 0.76 ENSDART00000157501
cldn15lb
claudin 15-like b
chr12_-_3237561 0.75 ENSDART00000164665
si:ch1073-13h15.3
si:ch1073-13h15.3
chr5_-_29238889 0.74 ENSDART00000143098
si:dkey-61l1.4
si:dkey-61l1.4
chr9_+_22364997 0.74 ENSDART00000188054
ENSDART00000046116
crygs3
crystallin, gamma S3
chr18_-_24988645 0.73 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr15_+_45563491 0.70 ENSDART00000191169
cldn15lb
claudin 15-like b
chr22_-_4439311 0.69 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr8_+_28695914 0.68 ENSDART00000033386
ocstamp
osteoclast stimulatory transmembrane protein
chr17_-_10838434 0.67 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr3_-_28828242 0.66 ENSDART00000151445
si:ch211-76l23.4
si:ch211-76l23.4
chr2_-_37956768 0.66 ENSDART00000034595
cbln10
cerebellin 10
chr12_+_2648043 0.65 ENSDART00000082220
gdf2
growth differentiation factor 2
chr19_+_9277327 0.65 ENSDART00000104623
ENSDART00000151164
si:rp71-15k1.1
si:rp71-15k1.1
chr2_-_37960688 0.63 ENSDART00000055565
cbln14
cerebellin 14
chr16_-_19373310 0.63 ENSDART00000148294
dnah11
dynein, axonemal, heavy chain 11
chr19_+_9186175 0.63 ENSDART00000039325
hcn3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr7_+_21841037 0.61 ENSDART00000077503
tm4sf5
transmembrane 4 L six family member 5
chr3_+_15828999 0.60 ENSDART00000104397
tmem11
transmembrane protein 11
chr16_-_16619854 0.58 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cyp21a2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr7_-_44957503 0.57 ENSDART00000165077
cdh16
cadherin 16, KSP-cadherin
chr16_+_52966812 0.57 ENSDART00000148435
ENSDART00000049099
ENSDART00000150117
trip13
thyroid hormone receptor interactor 13
chr6_-_43616936 0.55 ENSDART00000149301
foxp1b
forkhead box P1b
chr3_+_25191467 0.53 ENSDART00000156956
ENSDART00000154799
il2rb
interleukin 2 receptor, beta
chr10_+_36650222 0.53 ENSDART00000126963
ucp3
uncoupling protein 3
chr17_-_27266053 0.51 ENSDART00000110903
E2F2
si:ch211-160f23.5
chr1_+_58332000 0.50 ENSDART00000145234
ggt1l2.1
gamma-glutamyltransferase 1 like 2.1
chr18_-_41161828 0.49 ENSDART00000114993
CABZ01005876.1

chr20_-_22778394 0.49 ENSDART00000152645
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr22_-_9728208 0.48 ENSDART00000185962
si:dkey-286j17.4
si:dkey-286j17.4
chr19_+_7043634 0.46 ENSDART00000133954
mhc1uka
major histocompatibility complex class I UKA
chr7_+_29513161 0.46 ENSDART00000191846
si:dkey-182o15.5
si:dkey-182o15.5
chr18_+_14277003 0.45 ENSDART00000006628
zgc:173742
zgc:173742
chr2_+_36898982 0.45 ENSDART00000084859
rabgap1l2
RAB GTPase activating protein 1-like 2
chr9_+_3170101 0.43 ENSDART00000164878
ENSDART00000160567
ENSDART00000161216
dync1i2a
dynein, cytoplasmic 1, intermediate chain 2a
chr2_-_985417 0.42 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr8_+_37749263 0.42 ENSDART00000108556
ENSDART00000147942
npm2a
nucleophosmin/nucleoplasmin, 2a
chr20_-_2641233 0.38 ENSDART00000145335
ENSDART00000133121
bub1
BUB1 mitotic checkpoint serine/threonine kinase
chr4_+_57093908 0.38 ENSDART00000170198
si:ch211-238e22.5
si:ch211-238e22.5
chr8_-_46457233 0.38 ENSDART00000113214
sult1st7
sulfotransferase family 1, cytosolic sulfotransferase 7
chr4_-_12723585 0.38 ENSDART00000185639
mgst1.2
microsomal glutathione S-transferase 1.2
chr19_+_32856907 0.36 ENSDART00000148232
rpl30
ribosomal protein L30
chr21_+_22558187 0.35 ENSDART00000167599
chek1
checkpoint kinase 1
chr9_-_12269847 0.35 ENSDART00000136558
ENSDART00000144734
ENSDART00000131766
ENSDART00000032344
nup35
nucleoporin 35
chr5_+_4575800 0.34 ENSDART00000180952
cst14b.2
cystatin 14b, tandem duplicate 2
chr7_-_35515931 0.33 ENSDART00000193324
irx6a
iroquois homeobox 6a
chr19_+_816208 0.33 ENSDART00000093304
nrm
nurim
chr10_+_39248911 0.33 ENSDART00000170079
ENSDART00000167974
foxred1
FAD-dependent oxidoreductase domain containing 1
chr18_+_44532370 0.32 ENSDART00000086952
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr22_-_13042992 0.32 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr25_-_7759453 0.31 ENSDART00000142439
ENSDART00000021577
phf21ab
PHD finger protein 21Ab
chr24_+_13642126 0.31 ENSDART00000126769
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr6_+_40437987 0.31 ENSDART00000136487
ghrl
ghrelin/obestatin prepropeptide
chr22_+_1779401 0.30 ENSDART00000170126
znf1154
zinc finger protein 1154
chr21_-_9383974 0.30 ENSDART00000160932
sdad1
SDA1 domain containing 1
chr8_-_15150131 0.30 ENSDART00000138253
bcar3
BCAR3, NSP family adaptor protein
chr7_-_17600415 0.29 ENSDART00000080717
nitr6b
novel immune-type receptor 6b
chr21_-_9384374 0.28 ENSDART00000169275
sdad1
SDA1 domain containing 1
chr11_-_42752884 0.28 ENSDART00000186025
si:ch73-106k19.5
si:ch73-106k19.5
chr7_+_65387374 0.28 ENSDART00000188680
CLEC3A
C-type lectin domain family 3 member A
chr11_-_18819178 0.28 ENSDART00000080355
zgc:175264
zgc:175264
chr6_-_8704702 0.27 ENSDART00000064149
nabp1b
nucleic acid binding protein 1b
chr5_+_23152282 0.27 ENSDART00000166783
tbx5b
T-box 5b
chr15_-_16121496 0.27 ENSDART00000128624
sgk494a
uncharacterized serine/threonine-protein kinase SgK494a
chr19_-_42238440 0.26 ENSDART00000132591
si:ch211-191i18.4
si:ch211-191i18.4
chr2_+_23007675 0.26 ENSDART00000163649
mknk2a
MAP kinase interacting serine/threonine kinase 2a
chr11_-_20987378 0.25 ENSDART00000110140
taf4a
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr15_+_6459847 0.25 ENSDART00000157250
ENSDART00000065824
bace2
beta-site APP-cleaving enzyme 2
chr7_-_71585065 0.25 ENSDART00000128678
mettl4
methyltransferase like 4
chr11_+_14284866 0.25 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr7_+_22637515 0.24 ENSDART00000158698
si:dkey-112a7.5
si:dkey-112a7.5
chr10_+_26973063 0.24 ENSDART00000143162
ENSDART00000186210
tm7sf2
transmembrane 7 superfamily member 2
chr20_-_51355465 0.24 ENSDART00000151620
ENSDART00000151690
ENSDART00000110289
tcte1
t-complex-associated-testis-expressed 1
chr8_-_16697615 0.24 ENSDART00000187929
rpe65b
retinal pigment epithelium-specific protein 65b
chr4_-_75505048 0.24 ENSDART00000163665
si:dkey-71l4.5
si:dkey-71l4.5
chr14_+_46410766 0.23 ENSDART00000032342
anxa5a
annexin A5a
chr12_-_30583668 0.23 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr15_-_28677725 0.23 ENSDART00000060255
blmh
bleomycin hydrolase
chr6_-_39919982 0.23 ENSDART00000065091
ENSDART00000064903
sumf1
sulfatase modifying factor 1
chr4_-_71913556 0.23 ENSDART00000167608
si:dkey-92c21.1
si:dkey-92c21.1
chr14_-_28463835 0.22 ENSDART00000146344
ENSDART00000144076
nxt2
nuclear transport factor 2-like export factor 2
chr11_-_18818640 0.22 ENSDART00000191610
ENSDART00000190055
zgc:175264
zgc:175264
chr14_-_41556720 0.22 ENSDART00000149244
itga6l
integrin, alpha 6, like
chr9_+_52398531 0.22 ENSDART00000126215
dap1b
death associated protein 1b
chr16_-_30564319 0.22 ENSDART00000145087
lmna
lamin A
chr3_-_12227359 0.22 ENSDART00000167356
tfap4
transcription factor AP-4 (activating enhancer binding protein 4)
chr16_+_46492994 0.22 ENSDART00000134734
rpz5
rapunzel 5
chr3_-_39208714 0.21 ENSDART00000125730
si:ch211-232p21.6
si:ch211-232p21.6
chr20_+_43083745 0.21 ENSDART00000139014
ENSDART00000153438
moxd1l
monooxygenase, DBH-like 1, like
chr19_+_10536093 0.21 ENSDART00000138706
si:dkey-211g8.1
si:dkey-211g8.1
chr14_-_1635296 0.21 ENSDART00000186658
LO018564.1

chr5_-_61624693 0.21 ENSDART00000141323
si:dkey-261j4.4
si:dkey-261j4.4
chr14_-_26377044 0.20 ENSDART00000022236
emx3
empty spiracles homeobox 3
chr6_+_2097690 0.20 ENSDART00000193770
tgm2b
transglutaminase 2b
chr18_+_19974289 0.19 ENSDART00000090334
ENSDART00000192982
skor1b
SKI family transcriptional corepressor 1b
chr3_+_34683096 0.18 ENSDART00000084432
dusp3b
dual specificity phosphatase 3b
chr2_-_51221198 0.18 ENSDART00000166869
pigrl4.2
polymeric immunoglobulin receptor-like 4.2
chr16_+_11724230 0.18 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr2_-_6112862 0.18 ENSDART00000164269
prdx1
peroxiredoxin 1
chr2_-_51507540 0.17 ENSDART00000166605
ENSDART00000161093
pigrl2.3
polymeric immunoglobulin receptor-like 2.3
chr2_+_47906240 0.17 ENSDART00000122206
ftr23
finTRIM family, member 23
chr3_-_34724879 0.17 ENSDART00000177021
thraa
thyroid hormone receptor alpha a
chr1_-_40140424 0.17 ENSDART00000148234
si:ch211-113e8.10
si:ch211-113e8.10
chr5_+_54400971 0.16 ENSDART00000169695
bspry
B-box and SPRY domain containing
chr5_+_22970617 0.16 ENSDART00000192859
hmgn7
high mobility group nucleosomal binding domain 7
chr6_-_35051671 0.16 ENSDART00000132788
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr3_-_16289826 0.16 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr21_-_39327223 0.16 ENSDART00000115097
aifm5
apoptosis-inducing factor, mitochondrion-associated, 5
chr20_+_27647436 0.16 ENSDART00000180557
ENSDART00000185628
mthfd1a
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr1_+_532766 0.16 ENSDART00000179731
ENSDART00000060944
mrpl39
mitochondrial ribosomal protein L39
chr5_+_33070608 0.16 ENSDART00000135063
npffr2b
neuropeptide FF receptor 2b
chr20_+_26881600 0.15 ENSDART00000174799
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_-_42238003 0.15 ENSDART00000151022
si:ch211-191i18.4
si:ch211-191i18.4
chr6_+_41186320 0.15 ENSDART00000025241
opn1mw2
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr11_+_8660158 0.15 ENSDART00000169141
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr10_+_26597990 0.15 ENSDART00000079187
fhl1b
four and a half LIM domains 1b
chr8_+_29636431 0.15 ENSDART00000133047
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr12_+_23424108 0.15 ENSDART00000077732
bambia
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
chr16_-_1503023 0.14 ENSDART00000036348
sim1a
single-minded family bHLH transcription factor 1a
chr8_+_23142946 0.14 ENSDART00000152933
si:ch211-196c10.13
si:ch211-196c10.13
chr20_-_52603094 0.14 ENSDART00000136945
ENSDART00000133798
si:dkey-235d18.6
si:dkey-235d18.6
chr1_-_21287724 0.13 ENSDART00000193900
npy1r
neuropeptide Y receptor Y1
chr5_+_35398745 0.13 ENSDART00000098010
ptger4b
prostaglandin E receptor 4 (subtype EP4) b
chr4_-_6373735 0.13 ENSDART00000140100
MDFIC
si:ch73-156e19.1
chr22_+_31059919 0.13 ENSDART00000077063
sec13
SEC13 homolog, nuclear pore and COPII coat complex component
chr6_-_8264751 0.13 ENSDART00000091628
ccdc151
coiled-coil domain containing 151
chr16_-_7692568 0.12 ENSDART00000148980
pimr209
Pim proto-oncogene, serine/threonine kinase, related 209
chr22_-_5663354 0.12 ENSDART00000081774
ccdc51
coiled-coil domain containing 51
chr6_-_35052145 0.12 ENSDART00000073970
ENSDART00000185790
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr5_-_29671586 0.12 ENSDART00000098336
spaca9
sperm acrosome associated 9
chr23_+_28381260 0.12 ENSDART00000162722
zgc:153867
zgc:153867
chr7_+_67429185 0.11 ENSDART00000162553
ENSDART00000178646
kars
lysyl-tRNA synthetase
chr19_+_11984725 0.11 ENSDART00000185960
spag1a
sperm associated antigen 1a
chr17_-_10073926 0.11 ENSDART00000166081
ENSDART00000161574
zgc:109986
zgc:109986
chr12_-_20120702 0.11 ENSDART00000153387
ENSDART00000158412
ENSDART00000112768
ubald1a
UBA-like domain containing 1a
chr8_+_19624589 0.10 ENSDART00000185698
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr17_+_26828027 0.10 ENSDART00000042060
jade1
jade family PHD finger 1
chr2_-_5135125 0.10 ENSDART00000164039
ptmab
prothymosin, alpha b
chr14_-_33613794 0.10 ENSDART00000010022
xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr8_-_47329755 0.10 ENSDART00000060853
pex10
peroxisomal biogenesis factor 10
chr5_-_51756210 0.10 ENSDART00000163464
lhfpl2b
LHFPL tetraspan subfamily member 2b
chr20_+_39375280 0.10 ENSDART00000172434
pimr131
Pim proto-oncogene, serine/threonine kinase, related 131
chr4_-_40883162 0.10 ENSDART00000151978
znf1102
zinc finger protein 1102
chr15_+_17623115 0.09 ENSDART00000062378
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr4_-_45337903 0.09 ENSDART00000159767
si:dkey-247i3.6
si:dkey-247i3.6
chr5_-_67750907 0.09 ENSDART00000172097
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr17_+_30448452 0.09 ENSDART00000153939
lpin1
lipin 1
chr10_+_26972755 0.09 ENSDART00000042162
tm7sf2
transmembrane 7 superfamily member 2
chr15_+_25156382 0.09 ENSDART00000171092
slc35f2l
info solute carrier family 35, member F2, like
chr7_-_58776400 0.09 ENSDART00000167433
sox17
SRY (sex determining region Y)-box 17
chr16_+_43139504 0.08 ENSDART00000065643
dbf4
DBF4 zinc finger
chr10_-_22491353 0.08 ENSDART00000180783
ENSDART00000159564
epob
erythropoietin b
chr24_+_7631797 0.08 ENSDART00000187464
cavin1b
caveolae associated protein 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxd2_foxd5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0048785 hatching gland development(GO:0048785)
0.4 1.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.4 1.1 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.3 0.9 GO:0000256 allantoin catabolic process(GO:0000256)
0.2 1.4 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.2 1.2 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.2 1.0 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 0.6 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.3 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 1.0 GO:0044206 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.1 1.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.9 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.3 GO:0003218 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.1 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.2 GO:0050817 coagulation(GO:0050817) regulation of coagulation(GO:0050818) negative regulation of coagulation(GO:0050819)
0.1 1.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.2 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 0.7 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.7 GO:0032095 regulation of response to food(GO:0032095)
0.1 0.5 GO:0031179 peptide modification(GO:0031179)
0.1 0.2 GO:1901825 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 1.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.5 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 2.0 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.1 0.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.9 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.1 GO:0072020 proximal straight tubule development(GO:0072020)
0.0 0.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 3.7 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 3.0 GO:0007599 hemostasis(GO:0007599)
0.0 0.2 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0006999 NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.3 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.6 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.3 GO:0006956 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.0 0.1 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 0.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 3.0 GO:0006914 autophagy(GO:0006914)
0.0 0.3 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.8 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.1 1.0 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 1.2 GO:0042555 MCM complex(GO:0042555)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.9 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.7 GO:0000792 heterochromatin(GO:0000792)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.7 GO:0030286 dynein complex(GO:0030286)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.3 2.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.8 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 1.1 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.7 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.8 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.2 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 0.3 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.2 GO:0070513 death domain binding(GO:0070513)
0.1 0.5 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 2.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 4.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 1.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 1.3 GO:0042562 hormone binding(GO:0042562)
0.0 0.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 1.0 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 2.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 1.6 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.3 GO:0015278 calcium-release channel activity(GO:0015278)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 2.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 2.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.0 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein