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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxj1a+foxj1b

Z-value: 1.22

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Transcription factors associated with foxj1a+foxj1b

Gene Symbol Gene ID Gene Info
ENSDARG00000088290 forkhead box J1b
ENSDARG00000101919 forkhead box J1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxj1bdr11_v1_chr12_+_20149305_20149311-0.922.6e-02Click!
foxj1adr11_v1_chr3_+_60721342_60721342-0.903.9e-02Click!

Activity profile of foxj1a+foxj1b motif

Sorted Z-values of foxj1a+foxj1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_7391400 1.60 ENSDART00000169111
ENSDART00000186395
troponin I4a
chr4_+_7391110 1.48 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr1_+_53945934 1.39 ENSDART00000052838
actin, alpha 1a, skeletal muscle
chr23_-_5683147 0.94 ENSDART00000102766
ENSDART00000067351
troponin T type 2a (cardiac)
chr21_-_22951604 0.89 ENSDART00000083449
ENSDART00000180129
duboraya
chr21_+_10577527 0.84 ENSDART00000165070
ENSDART00000127963
collagen and calcium binding EGF domains 1
chr25_-_13188678 0.72 ENSDART00000125754
si:ch211-147m6.1
chr22_+_19553390 0.68 ENSDART00000061739
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr12_+_17100021 0.63 ENSDART00000177923
actin, alpha 2, smooth muscle, aorta
chr18_+_35842933 0.58 ENSDART00000151587
ENSDART00000131121
protein phosphatase 1, regulatory subunit 13 like
chr16_-_26731928 0.55 ENSDART00000135860
ring finger protein 41, like
chr10_+_22775253 0.52 ENSDART00000190141
transmembrane protein 88 a
chr25_-_27843066 0.50 ENSDART00000179684
ENSDART00000186000
ENSDART00000190065
ankyrin repeat and SOCS box containing 15a
chr17_+_15297398 0.50 ENSDART00000156574
si:ch211-270g19.5
chr24_-_37640705 0.49 ENSDART00000066583
zgc:112496
chr21_-_20840714 0.49 ENSDART00000144861
ENSDART00000139430
complement component 6
chr21_-_5881344 0.49 ENSDART00000009241
ribosomal protein L35
chr16_+_26732086 0.48 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr3_+_32671146 0.48 ENSDART00000039466
ring finger protein 25
chr8_-_30791266 0.48 ENSDART00000062220
glutathione S-transferase theta 1a
chr15_+_6661343 0.47 ENSDART00000160136
NOP53 ribosome biogenesis factor
chr8_-_30791089 0.47 ENSDART00000147332
glutathione S-transferase theta 1a
chr4_-_6373735 0.47 ENSDART00000140100
si:ch73-156e19.1
chr2_+_55365727 0.46 ENSDART00000162943

chr14_+_15155684 0.45 ENSDART00000167966
zgc:158852
chr17_-_20167206 0.45 ENSDART00000104874
ENSDART00000191995
prolyl 4-hydroxylase, alpha polypeptide I b
chr15_-_30816370 0.45 ENSDART00000142982
ENSDART00000050649
ENSDART00000136901
ENSDART00000100194
musashi RNA-binding protein 2b
chr21_-_3796461 0.45 ENSDART00000021976
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr4_-_16353733 0.44 ENSDART00000186785
lumican
chr19_+_30990815 0.43 ENSDART00000134645
syncoilin, intermediate filament protein
chr4_-_12795436 0.43 ENSDART00000131026
ENSDART00000075127
beta-2-microglobulin
chr2_-_38035235 0.42 ENSDART00000075904
cerebellin 5
chr15_+_34069746 0.42 ENSDART00000163513
ADP-ribosylation factor-like 4aa
chr7_-_28658143 0.41 ENSDART00000173556
adhesion G protein-coupled receptor G1
chr7_-_30127082 0.41 ENSDART00000173749
alpha-kinase 3b
chr3_-_13546610 0.40 ENSDART00000159647
amidohydrolase domain containing 2
chr11_+_7264457 0.40 ENSDART00000154182
receptor accessory protein 6
chr14_+_26439227 0.39 ENSDART00000054183
G protein-coupled receptor 137
chr16_-_24195252 0.39 ENSDART00000136205
ENSDART00000048599
ENSDART00000161547
ribosomal protein S19
chr6_-_55864687 0.39 ENSDART00000160991
cytochrome P450, family 24, subfamily A, polypeptide 1
chr5_-_34993242 0.39 ENSDART00000134516
ENSDART00000051295
basic transcription factor 3
chr10_-_17501528 0.38 ENSDART00000144847
solute carrier family 2 (facilitated glucose transporter), member 11-like
chr4_+_5842433 0.38 ENSDART00000124085
ENSDART00000179848
ubiquitin specific peptidase 18
chr15_-_28805493 0.38 ENSDART00000179617
CD3e molecule, epsilon associated protein
chr25_-_27842654 0.38 ENSDART00000154852
ENSDART00000156906
ankyrin repeat and SOCS box containing 15a
chr14_-_29799993 0.37 ENSDART00000133775
ENSDART00000005568
PDZ and LIM domain 3b
chr2_+_21000334 0.37 ENSDART00000062563
ENSDART00000147809
ras responsive element binding protein 1b
chr7_-_60831082 0.37 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr18_-_17399291 0.37 ENSDART00000192075
ENSDART00000060949
ENSDART00000188506
zinc finger protein, FOG family member 1
chr19_+_18739085 0.37 ENSDART00000188868
sperm acrosome associated 4 like
chr23_+_7692042 0.36 ENSDART00000018512
protein O-fucosyltransferase 1
chr25_+_28555584 0.36 ENSDART00000157046
si:ch211-190o6.3
chr4_-_17725008 0.36 ENSDART00000016658
choline phosphotransferase 1
chr16_+_33143503 0.35 ENSDART00000058471
ENSDART00000179385
rhomboid, veinlet-like 2 (Drosophila)
chr10_-_3416258 0.35 ENSDART00000005168
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr11_-_6048490 0.35 ENSDART00000066164
plasmalemma vesicle associated protein b
chr19_+_33476557 0.34 ENSDART00000181800
triple QxxK/R motif containing
chr2_+_38271392 0.34 ENSDART00000042100
homeobox and leucine zipper encoding a
chr15_-_4011013 0.33 ENSDART00000158029

chr14_-_35462148 0.33 ENSDART00000045809
sushi-repeat containing protein, X-linked 2
chr10_+_28428222 0.33 ENSDART00000135003
si:ch211-222e20.4
chr13_+_42602406 0.33 ENSDART00000133388
ENSDART00000147996
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
chr17_+_24111392 0.32 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
EH domain binding protein 1
chr16_+_22587661 0.32 ENSDART00000129612
ENSDART00000142241
Src homology 2 domain containing E
chr13_-_31647323 0.32 ENSDART00000135381
SIX homeobox 4a
chr25_-_13188214 0.31 ENSDART00000187298
si:ch211-147m6.1
chr23_-_31266586 0.31 ENSDART00000139746
si:dkey-261l7.2
chr21_-_11632403 0.31 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
calpastatin
chr22_-_28653074 0.31 ENSDART00000154717
collagen, type VIII, alpha 1b
chr5_-_19014589 0.31 ENSDART00000002624
RAN binding protein 1
chr4_-_12795030 0.30 ENSDART00000150427
beta-2-microglobulin
chr14_-_41478265 0.30 ENSDART00000149886
ENSDART00000016002
tetraspanin 7
chr22_-_2959005 0.29 ENSDART00000040701
inhibitor of growth family, member 5a
chr17_-_15747296 0.29 ENSDART00000153970
connexin 52.7
chr14_+_30910114 0.29 ENSDART00000187166
ENSDART00000078187
forkhead box O4
chr9_+_11293830 0.29 ENSDART00000144440
wingless-type MMTV integration site family, member 6b
chr17_+_43843536 0.29 ENSDART00000164097

chr2_+_19633493 0.29 ENSDART00000147989
Pim proto-oncogene, serine/threonine kinase, related 54
chr7_+_9904627 0.28 ENSDART00000172824
ceramide synthase 3a
chr20_-_54014539 0.28 ENSDART00000060466
si:dkey-241l7.6
chr5_+_29726428 0.28 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr25_-_26893006 0.27 ENSDART00000006709
dihydrolipoamide dehydrogenase
chr3_+_25216790 0.27 ENSDART00000156544
C1q and TNF related 6a
chr5_-_66160415 0.27 ENSDART00000073895
membrane bound O-acyltransferase domain containing 4
chr25_-_35360096 0.27 ENSDART00000154053
ENSDART00000171917
si:ch73-147o17.1
chr15_-_44465679 0.27 ENSDART00000054605
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr13_+_35635672 0.27 ENSDART00000148481
thrombospondin 2a
chr8_+_10305400 0.26 ENSDART00000172400
Pim-1 proto-oncogene, serine/threonine kinase
chr10_+_11260170 0.25 ENSDART00000155742
hydroxysteroid dehydrogenase like 2
chr14_-_36799280 0.25 ENSDART00000168615
ring finger protein 130
chr13_-_43149063 0.25 ENSDART00000099601
V-set immunoregulatory receptor
chr12_+_28117365 0.25 ENSDART00000066290
urotensin 2 receptor
chr20_+_10723292 0.25 ENSDART00000152805
si:ch211-182e10.4
chr17_+_25519089 0.24 ENSDART00000041721
crystallin beta-gamma domain containing 1a
chr8_+_49570884 0.24 ENSDART00000182117
ENSDART00000108613
RAS and EF-hand domain containing
chr17_-_2690083 0.24 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr17_-_23709347 0.24 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr13_+_18533005 0.24 ENSDART00000136024
finTRIM family, member 14-like
chr21_+_3796620 0.24 ENSDART00000099535
ENSDART00000144515
SPOUT domain containing methyltransferase 1
chr16_-_24605969 0.24 ENSDART00000163305
ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr5_+_44944778 0.24 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
doublesex and mab-3 related transcription factor 1
chr20_-_54014373 0.24 ENSDART00000152934
si:dkey-241l7.6
chr7_+_4694924 0.23 ENSDART00000144873
si:ch211-225k7.3
chr23_+_38159715 0.23 ENSDART00000137969
zgc:112994
chr20_-_1314355 0.23 ENSDART00000152436
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr23_+_33296588 0.23 ENSDART00000030368
si:ch211-226m16.3
chr17_-_26867725 0.23 ENSDART00000153590
si:dkey-221l4.10
chr10_+_40836378 0.23 ENSDART00000085792
tripartite motif containing 69
chr3_-_18410968 0.23 ENSDART00000041842
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
chr7_-_28549361 0.22 ENSDART00000173918
ENSDART00000054368
ENSDART00000113313
suppression of tumorigenicity 5
chr12_-_11457625 0.22 ENSDART00000012318
HtrA serine peptidase 1b
chr7_+_24165371 0.22 ENSDART00000173472
si:ch211-216p19.5
chr15_-_44052927 0.22 ENSDART00000166209
wu:fb44b02
chr10_-_23099809 0.22 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
notchless homolog 1 (Drosophila)
chr25_-_13202208 0.22 ENSDART00000168155
si:ch211-194m7.4
chr22_+_3184500 0.22 ENSDART00000176409
ENSDART00000160604
FtsJ RNA methyltransferase homolog 3
chr10_-_42237304 0.22 ENSDART00000140341
transcription factor 7 like 1a
chr4_-_1908179 0.21 ENSDART00000139586
anoctamin 6
chr15_+_14856307 0.21 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr22_+_11520249 0.21 ENSDART00000063147
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr16_-_7228276 0.21 ENSDART00000149030
5'-nucleotidase, cytosolic IIIA
chr20_+_26881600 0.21 ENSDART00000174799
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr7_-_36096582 0.21 ENSDART00000188507

chr5_+_12528693 0.21 ENSDART00000051670
replication factor C (activator 1) 5
chr15_-_7337148 0.21 ENSDART00000182568
high affinity cationic amino acid transporter 1
chr8_+_49065348 0.21 ENSDART00000032277
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr19_+_4051535 0.21 ENSDART00000167084
bloodthirsty-related gene family, member 24
chr1_-_30689004 0.21 ENSDART00000018827
dachshund c
chr23_-_27123171 0.21 ENSDART00000023218
ENSDART00000146467
signal transducer and activator of transcription 6, interleukin-4 induced
chr25_-_31423493 0.21 ENSDART00000027661
myogenic differentiation 1
chr24_-_31306724 0.20 ENSDART00000165399
acid phosphatase 5b, tartrate resistant
chr11_-_183328 0.20 ENSDART00000168562
advillin
chr1_+_9153141 0.20 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr17_+_36627099 0.20 ENSDART00000154104
interphotoreceptor matrix proteoglycan 1b
chr7_+_4732597 0.20 ENSDART00000134882
si:dkey-28d5.1
chr25_-_37435060 0.20 ENSDART00000102855
ENSDART00000148566
pyruvate dehydrogenase complex, component X
chr3_+_46762703 0.20 ENSDART00000133283
protein kinase C substrate 80K-H
chr24_+_37640626 0.20 ENSDART00000008047
WD repeat domain 24
chr20_+_6142433 0.20 ENSDART00000054084
ENSDART00000136986
transthyretin (prealbumin, amyloidosis type I)
chr22_-_9714593 0.20 ENSDART00000188282
si:dkey-286j17.4
chr1_+_51537250 0.20 ENSDART00000152789
ETAA1, ATR kinase activator
chr1_-_26702930 0.19 ENSDART00000109297
ENSDART00000152389
forkhead box E1
chr7_-_50367326 0.19 ENSDART00000141926
protein regulator of cytokinesis 1b
chr3_-_40664868 0.19 ENSDART00000138783
ENSDART00000178567
ring finger protein 216
chr13_+_30951155 0.19 ENSDART00000057469
ENSDART00000162254
V-set and transmembrane domain containing 4a
chr10_-_35257458 0.19 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr23_-_27701361 0.19 ENSDART00000186688
ENSDART00000183985
DnaJ (Hsp40) homolog, subfamily C, member 22
chr1_+_36651059 0.19 ENSDART00000187475
endothelin receptor type Aa
chr20_+_37383034 0.19 ENSDART00000134997
ENSDART00000145927
adhesion G protein-coupled receptor G6
chr2_+_19522082 0.19 ENSDART00000146098
Pim proto-oncogene, serine/threonine kinase, related 49
chr8_+_23034718 0.19 ENSDART00000184512
YTH N(6)-methyladenosine RNA binding protein 1
chr8_-_42624454 0.18 ENSDART00000075550
Kazal-type serine peptidase inhibitor domain 3
chr19_-_24958393 0.18 ENSDART00000098592
si:ch211-195b13.6
chr17_+_53284040 0.18 ENSDART00000165368
ataxin 3
chr20_+_25552057 0.18 ENSDART00000102913
cytochrome P450, family 2, subfamily V, polypeptide 1
chr5_+_39563301 0.18 ENSDART00000131245
ENSDART00000097872
si:ch211-57h10.1
chr18_-_48550426 0.18 ENSDART00000145189
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr6_-_18228358 0.18 ENSDART00000167937
prolyl 4-hydroxylase, beta polypeptide
chr10_-_34089779 0.18 ENSDART00000140070
Pim proto-oncogene, serine/threonine kinase, related 144
chr6_+_32834760 0.18 ENSDART00000121562
cylindromatosis (turban tumor syndrome), like
chr11_+_25430851 0.18 ENSDART00000164999
ENSDART00000126403
si:dkey-13a21.4
chr14_-_28566238 0.18 ENSDART00000172547
preproinsulin b
chr11_-_16394971 0.18 ENSDART00000180981
ENSDART00000179925
leucine-rich repeats and immunoglobulin-like domains 1
chr16_+_11699760 0.18 ENSDART00000156132
si:dkey-250k15.7
chr7_+_4694762 0.18 ENSDART00000132862
si:ch211-225k7.3
chr15_-_21849300 0.17 ENSDART00000183603
layilin b
chr13_-_21650404 0.17 ENSDART00000078352
tetraspanin 14
chr20_+_53368611 0.17 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr9_+_31222026 0.17 ENSDART00000145573
citrate lyase beta like
chr9_+_2041535 0.17 ENSDART00000093187
limb and neural patterns a
chr16_-_13595027 0.17 ENSDART00000060004
ntl-dependent gene 5
chr8_-_50133064 0.17 ENSDART00000030064
anthrax toxin receptor 1a
chr1_+_55239160 0.17 ENSDART00000152318
si:ch211-286b5.2
chr3_+_29510818 0.17 ENSDART00000055407
ENSDART00000193743
ENSDART00000123619
Rac family small GTPase 2
chr18_-_46280578 0.17 ENSDART00000131724
phospholipase D family, member 3
chr23_+_13533885 0.17 ENSDART00000144386
uridine-cytidine kinase 1-like 1b
chr23_+_24085531 0.17 ENSDART00000139710
tubulin tyrosine ligase-like family, member 10
chr4_-_49312747 0.17 ENSDART00000181057

chr1_-_54191626 0.16 ENSDART00000062941
nth-like DNA glycosylase 1
chr4_+_72578548 0.16 ENSDART00000174035
si:cabz01054394.5
chr22_+_7462997 0.16 ENSDART00000106082
zgc:112368
chr22_-_37686966 0.16 ENSDART00000192217
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr9_-_19161982 0.16 ENSDART00000081878
POU class 1 homeobox 1
chr7_-_26270014 0.16 ENSDART00000079347
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr23_+_24598910 0.16 ENSDART00000126510
ENSDART00000078796
KAT8 regulatory NSL complex subunit 2
chr21_+_15704556 0.16 ENSDART00000024858
ENSDART00000146909
coiled-coil-helix-coiled-coil-helix domain containing 10
chr7_-_24112484 0.16 ENSDART00000111923
ajuba LIM protein
chr16_+_10413551 0.16 ENSDART00000032877
ENSDART00000172827
INO80 complex subunit E
chr17_+_14965570 0.16 ENSDART00000066604
G protein-coupled receptor 137c
chr11_+_18612421 0.16 ENSDART00000110621
nuclear receptor coactivator 3
chr7_-_51300277 0.16 ENSDART00000174174
guanylyl cyclase 2
chr2_+_14992879 0.16 ENSDART00000137546
Pim proto-oncogene, serine/threonine kinase, related 55
chr6_+_29791164 0.16 ENSDART00000017424
prothymosin, alpha a
chr24_+_9298198 0.15 ENSDART00000165780
OTU deubiquitinase 1
chr8_-_10048059 0.15 ENSDART00000138411
si:dkey-8e10.3
chr7_-_3912905 0.15 ENSDART00000143864
si:dkey-88n24.10
chr25_+_19734038 0.15 ENSDART00000067354
zgc:101783
chr15_+_30158652 0.15 ENSDART00000190682
nemo-like kinase, type 2
chr23_-_43424510 0.15 ENSDART00000055564
regulation of nuclear pre-mRNA domain containing 1B
chr7_+_46003449 0.15 ENSDART00000159700
ENSDART00000173625
si:ch211-260e23.9

Network of associatons between targets according to the STRING database.

First level regulatory network of foxj1a+foxj1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0090131 mesenchyme migration(GO:0090131)
0.3 0.9 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 0.9 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 0.5 GO:2000726 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.1 0.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.8 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.1 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.4 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.3 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.1 0.3 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.1 0.5 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.2 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.2 GO:0030238 male sex determination(GO:0030238)
0.1 0.4 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.2 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.1 0.3 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.1 3.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.1 0.2 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.2 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.7 GO:0045824 negative regulation of toll-like receptor signaling pathway(GO:0034122) negative regulation of innate immune response(GO:0045824)
0.0 0.5 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 0.4 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.2 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0 0.5 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 0.1 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.2 GO:0045453 bone resorption(GO:0045453)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.2 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.4 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.3 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.5 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.2 GO:0098868 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0007286 spermatid development(GO:0007286)
0.0 0.3 GO:0007634 optokinetic behavior(GO:0007634)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 GO:0005869 dynactin complex(GO:0005869)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 4.0 GO:0005861 troponin complex(GO:0005861)
0.1 0.2 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.2 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.0 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.9 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.2 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.5 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.2 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 0.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.2 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.2 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.0 0.1 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.7 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 0.1 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0019213 deacetylase activity(GO:0019213)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids