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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxl1

Z-value: 0.95

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Transcription factors associated with foxl1

Gene Symbol Gene ID Gene Info
foxl1
ENSDARG00000008133 forkhead box L1
foxl1
ENSDARG00000111418 forkhead box L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxl1dr11_v1_chr18_-_17485419_174854190.856.8e-02Click!

Activity profile of foxl1 motif

Sorted Z-values of foxl1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_28124393 0.79 ENSDART00000089195
gpr17
G protein-coupled receptor 17
chr13_+_35745572 0.77 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr11_+_22374419 0.68 ENSDART00000174683
ENSDART00000170521
ENSDART00000193980
ppfia4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr1_-_54718863 0.61 ENSDART00000122601
pgam1b
phosphoglycerate mutase 1b
chr2_+_47581997 0.61 ENSDART00000112579
scg2b
secretogranin II (chromogranin C), b
chr19_-_28367413 0.56 ENSDART00000079092
si:dkey-261i16.5
si:dkey-261i16.5
chr13_+_28819768 0.55 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653
CU639469.1

chr7_+_20535869 0.54 ENSDART00000078181
zgc:158423
zgc:158423
chr2_+_31833997 0.54 ENSDART00000066788
epdr1
ependymin related 1
chr4_+_3287819 0.53 ENSDART00000168633
CABZ01085700.1

chr12_+_33151246 0.53 ENSDART00000162681
rbfox3a
RNA binding fox-1 homolog 3a
chr11_-_27702778 0.52 ENSDART00000045942
ENSDART00000125352
phf2
PHD finger protein 2
chr16_-_42390441 0.51 ENSDART00000148475
cspg5a
chondroitin sulfate proteoglycan 5a
chr21_-_39628771 0.50 ENSDART00000183995
aldocb
aldolase C, fructose-bisphosphate, b
chr21_-_42055872 0.49 ENSDART00000144767
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr14_+_34486629 0.48 ENSDART00000131861
tmsb2
thymosin beta 2
chr24_-_19719240 0.47 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr23_-_4915118 0.46 ENSDART00000060714
atp6ap1a
ATPase H+ transporting accessory protein 1a
chr16_+_36906693 0.46 ENSDART00000160645
si:ch73-215d9.1
si:ch73-215d9.1
chr25_-_8030425 0.44 ENSDART00000014964
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr17_+_15033822 0.43 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr16_+_23811554 0.43 ENSDART00000114336
si:dkey-7f3.9
si:dkey-7f3.9
chr21_+_3093419 0.42 ENSDART00000162520
SHC3
SHC adaptor protein 3
chr17_-_4318393 0.42 ENSDART00000167995
ENSDART00000153824
napba
N-ethylmaleimide-sensitive factor attachment protein, beta a
chr15_-_31514818 0.42 ENSDART00000153978
hmgb1b
high mobility group box 1b
chr7_+_26762958 0.40 ENSDART00000167956
ENSDART00000134717
tspan18a
tetraspanin 18a
chr8_-_32497815 0.40 ENSDART00000122359
si:dkey-164f24.2
si:dkey-164f24.2
chr4_-_19016396 0.40 ENSDART00000166160
si:dkey-31f5.11
si:dkey-31f5.11
chr11_-_44484952 0.40 ENSDART00000166674
ENSDART00000188016
mfn1b
mitofusin 1b
chr21_-_43482426 0.39 ENSDART00000192901
ankrd46a
ankyrin repeat domain 46a
chr1_+_8601935 0.39 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr16_-_15988320 0.39 ENSDART00000160883
CABZ01060453.1

chr22_+_11857356 0.39 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr14_+_31618982 0.39 ENSDART00000026195
slc9a6a
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr12_+_24344611 0.38 ENSDART00000093094
nrxn1a
neurexin 1a
chr24_+_402493 0.37 ENSDART00000036472
VSTM2A
zgc:110852
chr11_+_30282141 0.37 ENSDART00000122756
si:dkey-163f14.6
si:dkey-163f14.6
chr2_+_5563077 0.36 ENSDART00000111220
mb21d2
Mab-21 domain containing 2
chr6_-_55354004 0.36 ENSDART00000165911
pcif1
PDX1 C-terminal inhibiting factor 1
chr10_+_7029664 0.36 ENSDART00000166206
psd3l
pleckstrin and Sec7 domain containing 3, like
chr24_+_32176155 0.36 ENSDART00000003745
vim
vimentin
chr2_-_27775236 0.36 ENSDART00000187983
XKR4
zgc:123035
chr23_-_36934944 0.36 ENSDART00000109976
ENSDART00000162179
acap3a
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a
chr7_-_36358735 0.36 ENSDART00000188392
fto
fat mass and obesity associated
chr12_-_13886952 0.35 ENSDART00000110503
adam11
ADAM metallopeptidase domain 11
chr7_-_48173440 0.35 ENSDART00000124075
mtss1lb
metastasis suppressor 1-like b
chr7_-_58269812 0.35 ENSDART00000050077
sdcbp
syndecan binding protein (syntenin)
chr1_+_20635190 0.34 ENSDART00000145418
ENSDART00000148518
ENSDART00000139461
ENSDART00000102969
ENSDART00000166479
spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr24_-_32665283 0.33 ENSDART00000038364
ca2
carbonic anhydrase II
chr25_-_29363934 0.33 ENSDART00000166889
nptna
neuroplastin a
chr10_+_41549819 0.33 ENSDART00000114210
CABZ01049847.1

chr17_-_21200406 0.32 ENSDART00000104708
abhd12
abhydrolase domain containing 12
chr12_+_28574863 0.32 ENSDART00000153284
tbkbp1
TBK1 binding protein 1
chr6_-_13449556 0.32 ENSDART00000184566
ENSDART00000112883
ENSDART00000185377
fmnl2b
formin-like 2b
chr22_-_12862415 0.32 ENSDART00000145156
ENSDART00000137280
glsa
glutaminase a
chr16_+_30002605 0.32 ENSDART00000160555
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr1_-_21483832 0.31 ENSDART00000102790
glrba
glycine receptor, beta a
chr17_-_11015878 0.31 ENSDART00000162249
dact1
dishevelled-binding antagonist of beta-catenin 1
chr11_-_44163164 0.31 ENSDART00000047126
clcn4
chloride channel, voltage-sensitive 4
chr3_+_30190419 0.31 ENSDART00000157320
akt1s1
AKT1 substrate 1 (proline-rich)
chr25_-_13839743 0.31 ENSDART00000158780
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr24_+_31655939 0.31 ENSDART00000187337
CABZ01029422.1

chr25_-_10564721 0.31 ENSDART00000154776
galn
galanin/GMAP prepropeptide
chr5_-_40210447 0.31 ENSDART00000131323
si:dkey-193c22.1
si:dkey-193c22.1
chr24_-_5786759 0.30 ENSDART00000152069
chst2b
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2b
chr19_-_3973567 0.30 ENSDART00000167580
map7d1b
MAP7 domain containing 1b
chr1_+_45323142 0.30 ENSDART00000132210
emp1
epithelial membrane protein 1
chr12_+_35011899 0.30 ENSDART00000153007
ENSDART00000153020
qki2
QKI, KH domain containing, RNA binding 2
chr14_-_2189889 0.30 ENSDART00000181557
ENSDART00000106707
pcdh2ab9
pcdh2ab11
protocadherin 2 alpha b 9
protocadherin 2 alpha b 11
chr6_-_42049350 0.30 ENSDART00000022949
parp3
poly (ADP-ribose) polymerase family, member 3
chr3_-_20118342 0.30 ENSDART00000139902
selenow2a
selenoprotein W, 2a
chr25_-_8030113 0.30 ENSDART00000104674
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr13_+_11436130 0.29 ENSDART00000169895
zbtb18
zinc finger and BTB domain containing 18
chr12_-_34827477 0.29 ENSDART00000153026
NDUFAF8
si:dkey-21c1.6
chr7_+_69528850 0.29 ENSDART00000109507
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1
chr25_-_19224298 0.29 ENSDART00000149917
acanb
aggrecan b
chr22_+_4488454 0.29 ENSDART00000170620
ctxn1
cortexin 1
chr7_-_12852406 0.28 ENSDART00000173127
sh3gl3a
SH3-domain GRB2-like 3a
chr10_+_23060391 0.28 ENSDART00000079711
slc25a1a
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr5_+_4054704 0.28 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr14_-_2400269 0.28 ENSDART00000088833
si:ch73-233f7.1
si:ch73-233f7.1
chr12_+_2446837 0.28 ENSDART00000112032
ARHGAP22
si:dkey-191m6.4
chr16_-_44399335 0.28 ENSDART00000165058
rims2a
regulating synaptic membrane exocytosis 2a
chr23_+_1702624 0.28 ENSDART00000149357
rabggta
Rab geranylgeranyltransferase, alpha subunit
chr25_+_7321675 0.27 ENSDART00000104712
ENSDART00000142934
hmg20a
high mobility group 20A
chr7_+_7511914 0.27 ENSDART00000172848
clcn3
chloride channel 3
chr4_+_15605844 0.27 ENSDART00000101619
ENSDART00000021384
exoc4
exocyst complex component 4
chr22_-_21845685 0.27 ENSDART00000105564
aes
amino-terminal enhancer of split
chr5_+_1278092 0.27 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr25_-_13789955 0.27 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
ckap5
cytoskeleton associated protein 5
chr10_+_4499943 0.27 ENSDART00000125299
plk2a
polo-like kinase 2a (Drosophila)
chr4_-_23963838 0.27 ENSDART00000133433
ENSDART00000132615
ENSDART00000135942
ENSDART00000139439
celf2
cugbp, Elav-like family member 2
chr18_-_6856380 0.27 ENSDART00000175747
ppp6r2b
protein phosphatase 6, regulatory subunit 2b
chr25_-_7999756 0.26 ENSDART00000159908
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr25_+_16043246 0.26 ENSDART00000186663
sb:cb470
sb:cb470
chr3_+_17806213 0.26 ENSDART00000055890
znf385c
zinc finger protein 385C
chr2_-_45691128 0.26 ENSDART00000125406
fam102ba
family with sequence similarity 102, member B, a
chr16_+_1802307 0.26 ENSDART00000180026
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr2_+_45300512 0.26 ENSDART00000144704
camsap2b
calmodulin regulated spectrin-associated protein family, member 2b
chr15_-_26844591 0.26 ENSDART00000077582
pitpnm3
PITPNM family member 3
chr16_+_22649855 0.26 ENSDART00000143043
chrnb2b
cholinergic receptor, nicotinic, beta 2b
chr18_+_11506561 0.25 ENSDART00000121647
PRMT8
protein arginine methyltransferase 8
chr6_+_28018390 0.25 ENSDART00000123324
ENSDART00000150915
sap130a
Sin3A-associated protein a
chr5_+_9348284 0.25 ENSDART00000149417
tal2
T-cell acute lymphocytic leukemia 2
chr15_-_5740358 0.25 ENSDART00000183563
phkg1a
phosphorylase kinase, gamma 1a (muscle)
chr2_+_1881334 0.25 ENSDART00000161420
adgrl2b.1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr15_+_20548212 0.24 ENSDART00000193519
ENSDART00000169941
ENSDART00000187940
ENSDART00000183871
sgsm2
small G protein signaling modulator 2
chr21_+_41697552 0.24 ENSDART00000169511
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr25_-_3503458 0.24 ENSDART00000173269
PRKAR2B
si:ch211-272n13.7
chr8_+_17933475 0.24 ENSDART00000100651
erich3
glutamate-rich 3
chr25_+_20119466 0.24 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr25_+_1591964 0.24 ENSDART00000093277
ppm1h
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr10_+_21730585 0.23 ENSDART00000188576
pcdh1g22
protocadherin 1 gamma 22
chr16_-_7827365 0.23 ENSDART00000188101
tcaim
T cell activation inhibitor, mitochondrial
chr24_-_10919588 0.23 ENSDART00000131204
asap1b
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr21_+_31838386 0.23 ENSDART00000135591
si:ch211-12m10.1
si:ch211-12m10.1
chr4_+_9400012 0.23 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr6_-_49159207 0.23 ENSDART00000041942
tspan2a
tetraspanin 2a
chr16_+_6632969 0.23 ENSDART00000109276
sall3a
spalt-like transcription factor 3a
chr14_-_17306261 0.23 ENSDART00000191747
jakmip1
janus kinase and microtubule interacting protein 1
chr1_-_46343999 0.23 ENSDART00000145117
ENSDART00000193233
atp11a
ATPase phospholipid transporting 11A
chr16_-_3678976 0.23 ENSDART00000111823
GRIK3
glutamate ionotropic receptor kainate type subunit 3
chr19_-_1023051 0.22 ENSDART00000158429
tmem42b
transmembrane protein 42b
chr24_-_26632171 0.22 ENSDART00000008374
ENSDART00000017384
tnikb
TRAF2 and NCK interacting kinase b
chr8_-_21142550 0.22 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr2_+_34967022 0.22 ENSDART00000134926
astn1
astrotactin 1
chr9_+_19421841 0.22 ENSDART00000159090
ENSDART00000084771
pde9a
phosphodiesterase 9A
chr10_+_39199547 0.22 ENSDART00000075943
ei24
etoposide induced 2.4
chr18_-_39787040 0.22 ENSDART00000169916
dmxl2
Dmx-like 2
chr3_+_40576447 0.22 ENSDART00000083212
fscn1a
fascin actin-bundling protein 1a
chr4_-_75057322 0.22 ENSDART00000157935
large1
LARGE xylosyl- and glucuronyltransferase 1
chr16_+_7380463 0.21 ENSDART00000029727
ENSDART00000149086
atg5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr3_-_39305291 0.21 ENSDART00000102674
plcd3a
phospholipase C, delta 3a
chr4_+_17279966 0.21 ENSDART00000067005
ENSDART00000137487
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr10_+_16225117 0.21 ENSDART00000169885
slc12a2
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr24_+_15020402 0.21 ENSDART00000148102
dok6
docking protein 6
chr2_-_58193381 0.21 ENSDART00000159040
pnp5b
purine nucleoside phosphorylase 5b
chr10_+_3299829 0.21 ENSDART00000183684
zgc:56235
zgc:56235
chr12_+_15363463 0.21 ENSDART00000133533
plxdc1
plexin domain containing 1
chr5_+_37379825 0.21 ENSDART00000171826
klhl13
kelch-like family member 13
chr25_-_554142 0.21 ENSDART00000028997
myo9ab
myosin IXAb
chr3_-_55404985 0.20 ENSDART00000154274
mafga
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga
chr14_-_2358774 0.20 ENSDART00000164809
si:ch73-233f7.5
si:ch73-233f7.5
chr14_-_45967712 0.20 ENSDART00000043751
ENSDART00000141357
macrod1
MACRO domain containing 1
chr12_-_4028079 0.20 ENSDART00000128676
si:ch211-180a12.2
si:ch211-180a12.2
chr15_+_37105986 0.20 ENSDART00000157762
aplp1
amyloid beta (A4) precursor-like protein 1
chr10_+_16225553 0.20 ENSDART00000129844
slc12a2
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr7_-_12789251 0.20 ENSDART00000052750
adamtsl3
ADAMTS-like 3
chr22_-_26865361 0.20 ENSDART00000182504
hmox2a
heme oxygenase 2a
chr12_-_9084640 0.20 ENSDART00000125230
exoc6
exocyst complex component 6
chr1_+_29281764 0.20 ENSDART00000112106
fam155a
family with sequence similarity 155, member A
chr21_+_21791343 0.19 ENSDART00000151654
neu3.1
sialidase 3 (membrane sialidase), tandem duplicate 1
chr20_+_12702923 0.19 ENSDART00000163499
zgc:153383
zgc:153383
chr2_+_21312972 0.19 ENSDART00000080495
zbtb47a
zinc finger and BTB domain containing 47a
chr10_-_39198942 0.19 ENSDART00000077619
b3gat1b
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b
chr18_-_16590056 0.19 ENSDART00000143744
mgat4c
mgat4 family, member C
chr3_-_18711288 0.19 ENSDART00000183885
grid2ipa
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr11_-_24191928 0.19 ENSDART00000136827
sox12
SRY (sex determining region Y)-box 12
chr1_+_34763539 0.19 ENSDART00000077725
ENSDART00000113808
zgc:172122
zgc:172122
chr8_+_39619087 0.19 ENSDART00000134822
msi1
musashi RNA-binding protein 1
chr15_+_8767650 0.19 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr20_-_39596338 0.18 ENSDART00000023531
hey2
hes-related family bHLH transcription factor with YRPW motif 2
chr6_+_11026866 0.18 ENSDART00000189619
abcc6a
ATP-binding cassette, sub-family C (CFTR/MRP), member 6a
chr1_+_2101541 0.18 ENSDART00000128187
ENSDART00000167050
ENSDART00000182153
ENSDART00000122626
ENSDART00000164488
mbnl2
muscleblind-like splicing regulator 2
chr11_-_44979281 0.18 ENSDART00000190972
ldb1b
LIM-domain binding 1b
chr11_-_42980535 0.18 ENSDART00000181160
ENSDART00000192064
CABZ01069998.1

chr25_-_26843091 0.18 ENSDART00000130715
commd4
COMM domain containing 4
chr7_+_57795974 0.18 ENSDART00000148369
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr9_-_13963078 0.18 ENSDART00000193398
ENSDART00000061156
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr18_+_12058403 0.18 ENSDART00000140854
ENSDART00000193632
ENSDART00000190519
ENSDART00000190685
ENSDART00000112671
bicd1a
bicaudal D homolog 1a
chr4_-_1801519 0.18 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr3_+_27786601 0.18 ENSDART00000086994
nat15
N-acetyltransferase 15 (GCN5-related, putative)
chr11_-_25734417 0.18 ENSDART00000103570
brpf3a
bromodomain and PHD finger containing, 3a
chr15_+_17100412 0.17 ENSDART00000154418
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr2_-_9607879 0.17 ENSDART00000056899
txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr8_+_52530889 0.17 ENSDART00000127729
ENSDART00000170360
ENSDART00000162687
stambpb
STAM binding protein b
chr20_+_22799641 0.17 ENSDART00000131132
scfd2
sec1 family domain containing 2
chr5_+_19712011 0.17 ENSDART00000131924
fam222a
family with sequence similarity 222, member A
chr8_-_19467011 0.17 ENSDART00000162010
zgc:92140
zgc:92140
chr24_+_14595680 0.17 ENSDART00000137337
ENSDART00000091784
ENSDART00000136026
thtpa
thiamine triphosphatase
chr12_-_21834611 0.17 ENSDART00000179553
thrab
thyroid hormone receptor alpha b
chr2_+_22042745 0.17 ENSDART00000132039
tox
thymocyte selection-associated high mobility group box
chr15_-_20125331 0.16 ENSDART00000152355
med13b
mediator complex subunit 13b
chr19_+_40069524 0.16 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr14_+_21238682 0.16 ENSDART00000054462
ENSDART00000138551
smim19
small integral membrane protein 19
chr9_-_14504834 0.16 ENSDART00000056103
nrp2b
neuropilin 2b
chr11_+_42600731 0.16 ENSDART00000182753
ENSDART00000192028
ENSDART00000085868
appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr14_+_3411771 0.16 ENSDART00000164778
trpc3
transient receptor potential cation channel, subfamily C, member 3
chr8_+_2438638 0.16 ENSDART00000141263
ENKD1
si:ch211-220d9.3
chr1_-_24918686 0.16 ENSDART00000148076
fbxw7
F-box and WD repeat domain containing 7
chr20_+_45741566 0.15 ENSDART00000113454
chgb
chromogranin B
chr4_+_25950372 0.15 ENSDART00000125767
metap2a
methionyl aminopeptidase 2a
chr16_-_52728159 0.15 ENSDART00000158146
azin1a
antizyme inhibitor 1a
chr12_-_46959990 0.15 ENSDART00000084557
lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr18_-_6855991 0.15 ENSDART00000135206
ppp6r2b
protein phosphatase 6, regulatory subunit 2b
chr19_+_27342479 0.15 ENSDART00000184687
ddx39b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr18_+_7639401 0.15 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr12_-_10705916 0.15 ENSDART00000164038
FO704786.1

chr2_-_193707 0.15 ENSDART00000187642
znf1014
zinc finger protein 1014
chr12_-_35988586 0.15 ENSDART00000157746
pde6gb
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.4 GO:0042245 RNA repair(GO:0042245)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.2 GO:0097401 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.1 0.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.3 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.3 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.2 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.1 0.2 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.2 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 0.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.5 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.3 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.2 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.0 0.3 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.4 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.2 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.4 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.3 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 0.2 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.4 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:0099623 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.0 0.2 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.2 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.4 GO:0097178 ruffle assembly(GO:0097178)
0.0 1.4 GO:0006096 glycolytic process(GO:0006096)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0001881 receptor recycling(GO:0001881)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.3 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.1 GO:0051645 Golgi localization(GO:0051645)
0.0 0.5 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.2 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.5 GO:0006885 regulation of pH(GO:0006885) regulation of cellular pH(GO:0030641)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.5 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0035060 brahma complex(GO:0035060)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.1 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.9 GO:0030141 secretory granule(GO:0030141)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 0.3 GO:0045545 syndecan binding(GO:0045545)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.4 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 1.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.2 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0016933 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.4 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.2 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism