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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxm1

Z-value: 1.65

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Transcription factors associated with foxm1

Gene Symbol Gene ID Gene Info
foxm1
ENSDARG00000003200 forkhead box M1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxm1dr11_v1_chr4_-_5826320_58263200.771.2e-01Click!

Activity profile of foxm1 motif

Sorted Z-values of foxm1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_23770666 1.13 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr25_-_22187397 1.09 ENSDART00000123211
ENSDART00000139110
pkp3a
plakophilin 3a
chr19_+_48164242 1.09 ENSDART00000186574
prdm1b
PR domain containing 1b, with ZNF domain
chr15_-_41762530 0.89 ENSDART00000187125
ENSDART00000154971
ftr91
finTRIM family, member 91
chr3_-_19561058 0.87 ENSDART00000079323
zgc:163079
zgc:163079
chr22_+_835728 0.84 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr16_+_21801277 0.78 ENSDART00000088407
trim108
tripartite motif containing 108
chr3_+_1167026 0.74 ENSDART00000031823
ENSDART00000155340
triobpb
TRIO and F-actin binding protein b
chr5_-_38197080 0.71 ENSDART00000140708
si:ch211-284e13.9
si:ch211-284e13.9
chr22_-_17671348 0.71 ENSDART00000137995
tjp3
tight junction protein 3
chr14_+_20893065 0.69 ENSDART00000079452
lygl1
lysozyme g-like 1
chr14_+_45559268 0.68 ENSDART00000173152
RARRES3
zgc:154040
chr6_+_49881864 0.59 ENSDART00000075040
tubb1
tubulin, beta 1 class VI
chr7_+_15736230 0.57 ENSDART00000109942
mctp2b
multiple C2 domains, transmembrane 2b
chr3_-_33967767 0.56 ENSDART00000151493
ENSDART00000151160
ighv1-4
immunoglobulin heavy variable 1-4
chr10_-_244745 0.56 ENSDART00000136551
klhl35
kelch-like family member 35
chr20_+_16881883 0.55 ENSDART00000130107
nfkbiaa
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr3_-_49514874 0.54 ENSDART00000167179
asf1ba
anti-silencing function 1Ba histone chaperone
chr5_+_37068223 0.54 ENSDART00000164279
si:dkeyp-110c7.4
si:dkeyp-110c7.4
chr4_+_15944245 0.53 ENSDART00000134594
si:dkey-117n7.3
si:dkey-117n7.3
chr14_+_901847 0.52 ENSDART00000166991
si:ch73-208h1.2
si:ch73-208h1.2
chr1_+_19538299 0.51 ENSDART00000109416
smc2
structural maintenance of chromosomes 2
chr1_+_58370526 0.50 ENSDART00000067775
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr4_+_25558849 0.49 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
zgc:195175
chr1_+_59088205 0.49 ENSDART00000150649
ENSDART00000100197
zgc:173915
zgc:173915
chr22_+_17606863 0.45 ENSDART00000035670
polr2eb
polymerase (RNA) II (DNA directed) polypeptide E, b
chr14_-_22015232 0.45 ENSDART00000137795
ssrp1a
structure specific recognition protein 1a
chr21_-_13856689 0.45 ENSDART00000102197
fam129ba
family with sequence similarity 129, member Ba
chr18_-_16795262 0.44 ENSDART00000048722
ampd3b
adenosine monophosphate deaminase 3b
chr16_-_25841084 0.44 ENSDART00000159217
CR391937.1

chr5_-_64883082 0.44 ENSDART00000064983
ENSDART00000139066
krt1-c5
keratin, type 1, gene c5
chr18_-_20458412 0.43 ENSDART00000012241
kif23
kinesin family member 23
chr4_-_43731342 0.43 ENSDART00000146627
si:ch211-226o13.3
si:ch211-226o13.3
chr8_+_39724138 0.42 ENSDART00000009323
pla2g1b
phospholipase A2, group IB (pancreas)
chr21_-_3796461 0.42 ENSDART00000021976
nsa2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr6_+_56147812 0.41 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr18_-_20458840 0.41 ENSDART00000177125
kif23
kinesin family member 23
chr4_+_14981854 0.40 ENSDART00000067046
cax1
cation/H+ exchanger protein 1
chr17_+_8799661 0.40 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr17_+_5351922 0.40 ENSDART00000105394
runx2a
runt-related transcription factor 2a
chr15_-_44052927 0.40 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr24_+_17007407 0.39 ENSDART00000110652
zfx
zinc finger protein, X-linked
chr2_-_44777592 0.39 ENSDART00000113351
ENSDART00000169310
ncapd2
non-SMC condensin I complex, subunit D2
chr2_-_29996036 0.38 ENSDART00000020792
cnpy1
canopy1
chr1_+_55535827 0.38 ENSDART00000152784
adgre16
adhesion G protein-coupled receptor E16
chr25_+_28679672 0.38 ENSDART00000139965
ENSDART00000134072
cnot2
CCR4-NOT transcription complex, subunit 2
chr22_-_22301672 0.37 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr11_+_45153104 0.37 ENSDART00000159204
ENSDART00000177585
tk1
thymidine kinase 1, soluble
chr22_+_34615591 0.37 ENSDART00000189563
si:ch1073-214b20.2
si:ch1073-214b20.2
chr17_-_53440284 0.37 ENSDART00000126976
mycbp
c-myc binding protein
chr10_-_42237304 0.37 ENSDART00000140341
tcf7l1a
transcription factor 7 like 1a
chr19_-_340641 0.37 ENSDART00000183848
golph3l
golgi phosphoprotein 3-like
chr14_-_4177311 0.37 ENSDART00000128129
si:dkey-185e18.7
si:dkey-185e18.7
chr9_+_33216945 0.37 ENSDART00000134029
si:ch211-125e6.12
si:ch211-125e6.12
chr25_+_5039050 0.36 ENSDART00000154700
parvb
parvin, beta
chr16_-_24194587 0.36 ENSDART00000181520
rps19
ribosomal protein S19
chr3_+_37112693 0.35 ENSDART00000055228
ENSDART00000144278
ENSDART00000138079
psmc3ip
PSMC3 interacting protein
chr5_+_29820266 0.35 ENSDART00000146331
ENSDART00000098315
f11r.2
F11 receptor, tandem duplicate 2
chr5_-_24333684 0.35 ENSDART00000051553
znf703
zinc finger protein 703
chr11_-_18017918 0.35 ENSDART00000040171
qrich1
glutamine-rich 1
chr18_+_27000850 0.34 ENSDART00000188906
ENSDART00000086131
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr16_-_31675669 0.34 ENSDART00000168848
ENSDART00000158331
c1r
complement component 1, r subcomponent
chr13_+_31550185 0.33 ENSDART00000127843
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr15_+_47362728 0.33 ENSDART00000180712
CABZ01099833.1

chr14_-_52480661 0.32 ENSDART00000158353
exosc3
exosome component 3
chr1_-_56208151 0.32 ENSDART00000183325
si:dkey-76b14.2
si:dkey-76b14.2
chr20_+_6663544 0.32 ENSDART00000135390
tns3.2
tensin 3, tandem duplicate 2
chr7_+_10592152 0.32 ENSDART00000182624
fah
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr11_+_36683859 0.32 ENSDART00000170102
si:ch211-11c3.12
si:ch211-11c3.12
chr17_-_53439866 0.32 ENSDART00000154826
mycbp
c-myc binding protein
chr19_-_18626952 0.32 ENSDART00000168004
ENSDART00000162034
ENSDART00000165486
ENSDART00000167971
rps18
ribosomal protein S18
chr23_+_25305431 0.32 ENSDART00000143291
RPL41
si:dkey-151g10.6
chr11_-_25213651 0.32 ENSDART00000097316
ENSDART00000152186
myh7ba
myosin, heavy chain 7B, cardiac muscle, beta a
chr15_+_37589698 0.30 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin37
lin-37 DREAM MuvB core complex component
chr19_+_31904836 0.29 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr14_-_16082806 0.29 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr7_+_60359347 0.29 ENSDART00000145201
ENSDART00000039827
ppp1r14bb
protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
chr12_-_9516981 0.29 ENSDART00000106285
si:ch211-207i20.3
si:ch211-207i20.3
chr1_+_12348213 0.29 ENSDART00000144920
ENSDART00000138759
ENSDART00000067082
clta
clathrin, light chain A
chr11_-_18107447 0.28 ENSDART00000187376
qrich1
glutamine-rich 1
chr7_+_17933384 0.28 ENSDART00000173701
mta2
metastasis associated 1 family, member 2
chr18_+_19120984 0.27 ENSDART00000141501
si:dkey-242h9.3
si:dkey-242h9.3
chr3_-_54607166 0.27 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr9_+_21259820 0.27 ENSDART00000137024
ENSDART00000132324
ska3
spindle and kinetochore associated complex subunit 3
chr14_-_8453192 0.27 ENSDART00000136947
eif1ad
eukaryotic translation initiation factor 1A domain containing
chr18_-_15932704 0.27 ENSDART00000127769
plekhg7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr7_-_51102479 0.27 ENSDART00000174023
col4a6
collagen, type IV, alpha 6
chr2_-_59231017 0.27 ENSDART00000143980
ENSDART00000184190
ftr29
finTRIM family, member 29
chr14_+_21686207 0.26 ENSDART00000034438
ran
RAN, member RAS oncogene family
chr4_+_60492313 0.26 ENSDART00000191043
ENSDART00000191631
si:dkey-211i20.2
si:dkey-211i20.2
chr19_-_46018152 0.25 ENSDART00000159206
krit1
KRIT1, ankyrin repeat containing
chr22_+_30543437 0.25 ENSDART00000137983
si:dkey-103k4.1
si:dkey-103k4.1
chr5_-_9948497 0.25 ENSDART00000183196
tor4ab
torsin family 4, member Ab
chr15_-_37589600 0.25 ENSDART00000154641
proser3
proline and serine rich 3
chr1_-_55166511 0.25 ENSDART00000150430
ENSDART00000035725
pane1
proliferation associated nuclear element
chr22_+_31059919 0.25 ENSDART00000077063
sec13
SEC13 homolog, nuclear pore and COPII coat complex component
chr2_-_10338759 0.25 ENSDART00000150166
ENSDART00000149584
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr2_+_25840463 0.24 ENSDART00000125178
eif5a2
eukaryotic translation initiation factor 5A2
chr12_+_17154655 0.24 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr2_+_33926911 0.24 ENSDART00000109849
ENSDART00000135884
kif2c
kinesin family member 2C
chr4_+_33871518 0.24 ENSDART00000185054
si:dkey-28i19.3
si:dkey-28i19.3
chr9_-_31108285 0.24 ENSDART00000003193
gpr183a
G protein-coupled receptor 183a
chr18_+_27001115 0.24 ENSDART00000133547
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr10_+_6121558 0.24 ENSDART00000166799
ENSDART00000157947
tln1
talin 1
chr17_+_23975762 0.24 ENSDART00000155941
xpo1b
exportin 1 (CRM1 homolog, yeast) b
chr9_-_38036984 0.24 ENSDART00000134574
hacd2
3-hydroxyacyl-CoA dehydratase 2
chr4_-_16824556 0.24 ENSDART00000165289
ENSDART00000185839
gys2
glycogen synthase 2
chr22_+_1556948 0.24 ENSDART00000159050
si:ch211-255f4.8
si:ch211-255f4.8
chr11_+_45286911 0.23 ENSDART00000181763
pycr1b
pyrroline-5-carboxylate reductase 1b
chr22_+_9287929 0.23 ENSDART00000193522
si:ch211-250k18.7
si:ch211-250k18.7
chr10_-_35257458 0.23 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr17_-_11439815 0.23 ENSDART00000130105
psma3
proteasome subunit alpha 3
chr10_-_35051691 0.23 ENSDART00000108670
ENSDART00000190711
supt20
SPT20 homolog, SAGA complex component
chr4_-_68913650 0.23 ENSDART00000184297
si:dkey-264f17.5
si:dkey-264f17.5
chr3_+_1107102 0.23 ENSDART00000092690
srebf2
sterol regulatory element binding transcription factor 2
chr17_-_50301313 0.23 ENSDART00000125772
si:ch73-50f9.4
si:ch73-50f9.4
chr16_-_32303835 0.23 ENSDART00000191408
mms22l
MMS22-like, DNA repair protein
chr13_-_22961605 0.22 ENSDART00000143112
ENSDART00000057641
tspan15
tetraspanin 15
chr10_+_40629616 0.22 ENSDART00000147476
CR396590.9

chr21_+_3796620 0.22 ENSDART00000099535
ENSDART00000144515
spout1
SPOUT domain containing methyltransferase 1
chr7_-_3639171 0.22 ENSDART00000064280
si:ch211-282j17.1
si:ch211-282j17.1
chr4_-_16824231 0.22 ENSDART00000014007
gys2
glycogen synthase 2
chr24_+_5893134 0.22 ENSDART00000077941
mastl
microtubule associated serine/threonine kinase-like
chr13_+_37653851 0.22 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
phf3
PHD finger protein 3
chr19_-_11966015 0.22 ENSDART00000123409
si:ch1073-296d18.1
si:ch1073-296d18.1
chr15_-_28082310 0.21 ENSDART00000152620
dhrs13a.3
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr4_-_12718367 0.21 ENSDART00000035259
mgst1.1
microsomal glutathione S-transferase 1.1
chr4_+_47445318 0.21 ENSDART00000183819
si:dkey-124l13.1
si:dkey-124l13.1
chr22_-_23706771 0.21 ENSDART00000159771
cfhl1
complement factor H like 1
chr4_+_75537772 0.21 ENSDART00000168380
si:ch211-227e10.1
si:ch211-227e10.1
chr16_-_17175731 0.20 ENSDART00000183057
opn9
opsin 9
chr15_-_14210382 0.20 ENSDART00000179599
CR925813.1

chr10_-_35052198 0.20 ENSDART00000147805
supt20
SPT20 homolog, SAGA complex component
chr22_+_5851122 0.20 ENSDART00000082044
zmp:0000001161
zmp:0000001161
chr13_+_25421531 0.20 ENSDART00000158093
calhm2
calcium homeostasis modulator 2
chr11_-_28614608 0.20 ENSDART00000065853
dhrs3b
dehydrogenase/reductase (SDR family) member 3b
chr13_+_5978809 0.20 ENSDART00000102563
ENSDART00000121598
phf10
PHD finger protein 10
chr11_-_11336986 0.20 ENSDART00000016677
zgc:77929
zgc:77929
chr12_+_19191787 0.19 ENSDART00000152892
slc16a8
solute carrier family 16 (monocarboxylate transporter), member 8
chr12_-_23365737 0.19 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr6_-_16804001 0.19 ENSDART00000155398
pimr40
Pim proto-oncogene, serine/threonine kinase, related 40
chr7_+_24114694 0.19 ENSDART00000127177
mrpl52
mitochondrial ribosomal protein L52
chr11_-_2250767 0.18 ENSDART00000018131
hnrnpa1a
heterogeneous nuclear ribonucleoprotein A1a
chr2_+_11205795 0.18 ENSDART00000019078
lhx8a
LIM homeobox 8a
chr22_+_9239831 0.18 ENSDART00000133720
si:ch211-250k18.5
si:ch211-250k18.5
chr7_+_55950229 0.18 ENSDART00000082780
ACSF3
acyl-CoA synthetase family member 3
chr5_-_16475682 0.18 ENSDART00000090695
piwil2
piwi-like RNA-mediated gene silencing 2
chr20_-_10487951 0.18 ENSDART00000064112
glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr14_+_31865099 0.18 ENSDART00000189124
tm9sf5
transmembrane 9 superfamily protein member 5
chr18_+_44768829 0.18 ENSDART00000016271
ilvbl
ilvB (bacterial acetolactate synthase)-like
chr7_+_4625915 0.17 ENSDART00000108557
si:ch211-225k7.3
si:ch211-225k7.3
chr11_+_6422374 0.17 ENSDART00000183148
FO681393.1

chr13_+_33655404 0.17 ENSDART00000023379
mgme1
mitochondrial genome maintenance exonuclease 1
chr7_-_6444011 0.17 ENSDART00000173010
zgc:112234
zgc:112234
chr4_+_5196469 0.17 ENSDART00000067386
rad51ap1
RAD51 associated protein 1
chr11_+_2416064 0.17 ENSDART00000067117
ube2v1
ubiquitin-conjugating enzyme E2 variant 1
chr4_-_22472653 0.16 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
kmt2e
lysine (K)-specific methyltransferase 2E
chr21_-_23046606 0.16 ENSDART00000016167
zw10
zw10 kinetochore protein
chr11_-_13611132 0.16 ENSDART00000113055
si:ch211-1a19.2
si:ch211-1a19.2
chr21_+_40685895 0.16 ENSDART00000017709
ccdc82
coiled-coil domain containing 82
chr7_+_4572727 0.16 ENSDART00000137830
si:dkey-83f18.7
si:dkey-83f18.7
chr20_-_5291012 0.16 ENSDART00000122892
cyp46a1.3
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr8_+_23147218 0.16 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr3_-_37082618 0.16 ENSDART00000026701
ENSDART00000110716
tubg1
tubulin, gamma 1
chr12_+_30234209 0.16 ENSDART00000102081
afap1l2
actin filament associated protein 1-like 2
chr11_-_18017287 0.16 ENSDART00000155443
qrich1
glutamine-rich 1
chr13_+_44857087 0.16 ENSDART00000017770
zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr6_-_16948040 0.16 ENSDART00000156433
pimr30
Pim proto-oncogene, serine/threonine kinase, related 30
chr9_+_27354414 0.16 ENSDART00000163804
tlr20.2
toll-like receptor 20, tandem duplicate 2
chr9_+_1137430 0.15 ENSDART00000187062
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr7_+_1505507 0.15 ENSDART00000161015
nop10
NOP10 ribonucleoprotein homolog (yeast)
chr21_+_37436907 0.15 ENSDART00000182611
ENSDART00000076328
pgrmc1
progesterone receptor membrane component 1
chr5_-_67757188 0.15 ENSDART00000167168
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr4_-_17725008 0.15 ENSDART00000016658
chpt1
choline phosphotransferase 1
chr4_+_59234719 0.15 ENSDART00000170724
ENSDART00000192143
ENSDART00000109914
znf1086
zinc finger protein 1086
chr6_-_54444929 0.15 ENSDART00000154121
sys1
Sys1 golgi trafficking protein
chr13_+_29470442 0.15 ENSDART00000028417
lrit2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr22_-_6066867 0.15 ENSDART00000142383
si:dkey-19a16.1
si:dkey-19a16.1
chr12_-_43428542 0.15 ENSDART00000192266
ptprea
protein tyrosine phosphatase, receptor type, E, a
chr16_-_31445781 0.15 ENSDART00000056551
csnk2a1
casein kinase 2, alpha 1 polypeptide
chr20_+_25904199 0.15 ENSDART00000016864
slc35f6
solute carrier family 35, member F6
chr3_+_2719243 0.14 ENSDART00000189256
CR388047.3

chr4_+_75577480 0.14 ENSDART00000188196
si:ch211-227e10.1
si:ch211-227e10.1
chr25_-_24202576 0.14 ENSDART00000048507
uevld
UEV and lactate/malate dehyrogenase domains
chr6_+_40922572 0.14 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr13_+_24679674 0.14 ENSDART00000033090
ENSDART00000139854
zgc:66426
zgc:66426
chr1_-_18585046 0.14 ENSDART00000147228
fam114a1
family with sequence similarity 114, member A1
chr14_-_38826739 0.14 ENSDART00000187633
spdl1
spindle apparatus coiled-coil protein 1
chr15_-_18232712 0.14 ENSDART00000081199
wu:fj20b03
wu:fj20b03
chr16_-_53800047 0.14 ENSDART00000158047
znrf2b
zinc and ring finger 2b
chr3_-_11040575 0.13 ENSDART00000159802
CR382337.2

chr4_+_47789703 0.13 ENSDART00000161323
si:ch211-196h24.2
si:ch211-196h24.2
chr16_+_40131473 0.13 ENSDART00000155421
ENSDART00000134732
ENSDART00000138699
cenpw
si:ch211-195p4.4
centromere protein W
si:ch211-195p4.4
chr7_+_24115082 0.13 ENSDART00000182718
mrpl52
mitochondrial ribosomal protein L52
chr6_-_29288155 0.13 ENSDART00000078630
nme7
NME/NM23 family member 7
chr2_-_14793343 0.13 ENSDART00000132264
si:ch73-366i20.1
si:ch73-366i20.1
chr22_-_8692305 0.13 ENSDART00000181602
CR450686.4

chr4_-_36032177 0.13 ENSDART00000170143
zgc:174180
zgc:174180
chr4_-_890220 0.13 ENSDART00000022668
aim1b
crystallin beta-gamma domain containing 1b
chr18_+_17534627 0.13 ENSDART00000061007
mt2
metallothionein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of foxm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 0.5 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.1 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.8 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.3 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.5 GO:0031652 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.3 GO:0045601 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.1 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.2 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.7 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 0.7 GO:0030104 water homeostasis(GO:0030104)
0.1 0.3 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.1 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.2 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.2 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.7 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.3 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.0 0.4 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.2 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.5 GO:0090559 regulation of membrane permeability(GO:0090559)
0.0 0.4 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.1 GO:1903430 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0035790 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.5 GO:0009746 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.6 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0051228 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.0 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:0090497 mesenchymal cell migration(GO:0090497)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0035101 FACT complex(GO:0035101)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.2 GO:0005948 acetolactate synthase complex(GO:0005948)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.3 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0030132 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130) clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.6 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.5 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.1 0.4 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.3 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.2 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.2 GO:0003984 acetolactate synthase activity(GO:0003984)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.2 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.0 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 1.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism