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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxo3b+foxo6a+foxo6b

Z-value: 0.26

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Transcription factors associated with foxo3b+foxo6a+foxo6b

Gene Symbol Gene ID Gene Info
ENSDARG00000024619 forkhead box O6 b
ENSDARG00000042904 forkhead box O3b
ENSDARG00000100486 forkhead box O6 a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxo6bdr11_v1_chr19_+_15571290_15571290-0.533.6e-01Click!
foxo6adr11_v1_chr16_-_7362806_7362806-0.444.6e-01Click!
foxo3bdr11_v1_chr20_-_32332736_32332736-0.365.5e-01Click!

Activity profile of foxo3b+foxo6a+foxo6b motif

Sorted Z-values of foxo3b+foxo6a+foxo6b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_19299309 0.13 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr20_-_33583779 0.13 ENSDART00000097823
rho-associated, coiled-coil containing protein kinase 2b
chr12_+_31713239 0.12 ENSDART00000122379
hyaluronan binding protein 2
chr2_+_10134345 0.11 ENSDART00000100725
alpha-2-HS-glycoprotein 2
chr5_+_46196147 0.09 ENSDART00000084112
coagulation factor II (thrombin) receptor
chr19_-_30447611 0.08 ENSDART00000073705
ENSDART00000048977
ENSDART00000191237
ATP-binding cassette, sub-family F (GCN20), member 1
chr2_+_44571200 0.08 ENSDART00000098132
kelch-like family member 24a
chr5_+_29652513 0.07 ENSDART00000035400
TSC complex subunit 1a
chr22_+_25753972 0.07 ENSDART00000188417

chr23_+_17417539 0.07 ENSDART00000182605

chr21_-_22669669 0.07 ENSDART00000101784
grass carp reovirus (GCRV)-induced gene 2j
chr5_+_29652198 0.06 ENSDART00000184083
TSC complex subunit 1a
chr24_-_36723116 0.06 ENSDART00000088204
si:ch73-334d15.1
chr10_+_38526496 0.06 ENSDART00000144329
alkaline ceramidase 3
chr17_+_24111392 0.06 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
EH domain binding protein 1
chr22_-_23590069 0.06 ENSDART00000172067
coagulation factor XIII, B polypeptide
chr7_+_44445595 0.06 ENSDART00000108766
cadherin 5
chr17_-_10059557 0.06 ENSDART00000092209
ENSDART00000161243
bromodomain adjacent to zinc finger domain, 1A
chr16_-_45178430 0.06 ENSDART00000165186
si:dkey-33i11.9
chr5_-_25733745 0.06 ENSDART00000051566
zgc:101016
chr9_+_426392 0.06 ENSDART00000172515
basic leucine zipper and W2 domains 1b
chr6_-_57476465 0.05 ENSDART00000128065
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr23_-_30045661 0.05 ENSDART00000122239
ENSDART00000103480
coiled-coil domain containing 187
chr16_+_12517535 0.05 ENSDART00000155407
Ras interacting protein 1
chr7_+_30240791 0.05 ENSDART00000109243
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr3_+_25195966 0.05 ENSDART00000112338
interleukin 2 receptor, beta
chr2_-_7131657 0.05 ENSDART00000175565
ENSDART00000092116
exostosin-like glycosyltransferase 2
chr14_-_46238186 0.05 ENSDART00000173245
si:ch211-113d11.6
chr15_+_1134870 0.05 ENSDART00000155392
purinergic receptor P2Y13
chr10_+_25369254 0.05 ENSDART00000164375
BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
chr9_+_27720428 0.04 ENSDART00000112415
leucine carboxyl methyltransferase 2
chr5_+_30179010 0.04 ENSDART00000134624
ADAM metallopeptidase with thrombospondin type 1 motif, 15a
chr7_-_30174882 0.04 ENSDART00000110409
FERM domain containing 5
chr4_+_38547203 0.04 ENSDART00000171349
si:ch211-209n20.1
chr20_+_25340814 0.04 ENSDART00000063028
connective tissue growth factor a
chr1_+_42874410 0.04 ENSDART00000153506
catenin (cadherin-associated protein), alpha 2
chr19_-_7441948 0.04 ENSDART00000003544
GA binding protein transcription factor, beta subunit 2a
chr22_-_10440688 0.04 ENSDART00000111962
nucleolar protein 8
chr15_-_44465679 0.04 ENSDART00000054605
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr23_+_28322986 0.04 ENSDART00000134710
baculoviral IAP repeat containing 5b
chr11_+_14343445 0.04 ENSDART00000171347
ENSDART00000170547
si:ch211-262i1.6
chr21_-_29110607 0.04 ENSDART00000181595
hepatitis A virus cellular receptor 1
chr13_-_37102522 0.04 ENSDART00000147884
spectrin repeat containing, nuclear envelope 2b
chr18_-_10995410 0.04 ENSDART00000136751
tetraspanin 33b
chr20_+_13956106 0.03 ENSDART00000152826
si:dkey-249p7.4
chr23_+_4777612 0.03 ENSDART00000135933
vestigial-like family member 4a
chr16_-_31351419 0.03 ENSDART00000178298
ENSDART00000018091
maestro heat-like repeat family member 1
chr13_-_37103126 0.03 ENSDART00000135935
spectrin repeat containing, nuclear envelope 2b
chr1_-_43915423 0.03 ENSDART00000181915
ENSDART00000113673
secretory calcium-binding phosphoprotein 5
chr20_-_54208344 0.03 ENSDART00000169386
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a
chr23_+_42482137 0.03 ENSDART00000160199
cytochrome P450, family 2, subfamily AA, polypeptide 3
chr22_+_2533514 0.03 ENSDART00000147967
si:ch73-92e7.4
chr24_-_33284945 0.03 ENSDART00000155429
ENSDART00000112845
zgc:195173
chr13_-_31377299 0.03 ENSDART00000026692
ubiquitin domain containing 1a
chr23_+_36308428 0.03 ENSDART00000134607
heterogeneous nuclear ribonucleoprotein A1b
chr2_-_24907741 0.03 ENSDART00000155013
si:dkey-149i17.11
chr1_+_29515160 0.03 ENSDART00000152226
si:dkey-228l14.1
chr14_-_45551572 0.03 ENSDART00000111410
glucosidase, alpha; neutral AB
chr6_+_55819038 0.03 ENSDART00000108786
si:ch211-81n22.1
chr21_-_37973081 0.03 ENSDART00000136569
ripply transcriptional repressor 1
chr3_-_34051363 0.03 ENSDART00000151768
immunoglobulin heavy variable 3-2
chr25_-_36261836 0.03 ENSDART00000179411
dihydrouridine synthase 2
chr11_-_21404044 0.03 ENSDART00000080116
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr17_-_2834764 0.03 ENSDART00000024027
bradykinin receptor B1
chr2_+_22409249 0.03 ENSDART00000182915
zgc:56628
chr8_-_18010735 0.03 ENSDART00000125014
acyl-CoA thioesterase 11b
chr6_-_18531760 0.03 ENSDART00000167167
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr25_+_10953351 0.03 ENSDART00000154050
major histocompatibility complex class I LDA
chr15_-_4011013 0.03 ENSDART00000158029

chr19_-_7441686 0.03 ENSDART00000168194
GA binding protein transcription factor, beta subunit 2a
chr7_+_32021982 0.03 ENSDART00000173848
methyltransferase like 15
chr9_+_24088062 0.03 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr8_+_28695914 0.03 ENSDART00000033386
osteoclast stimulatory transmembrane protein
chr18_+_41527877 0.03 ENSDART00000146972
selenoprotein T, 1b
chr5_-_56513825 0.03 ENSDART00000024207
T-box 2a
chr9_+_30211038 0.03 ENSDART00000190847
SUMO1/sentrin specific peptidase 7a
chr9_-_52386733 0.03 ENSDART00000171721
death associated protein 1b
chr8_-_49201258 0.03 ENSDART00000114584
ENSDART00000142172
zgc:171501
chr3_+_23710839 0.03 ENSDART00000151584
homeobox B4a
chr19_-_47323267 0.02 ENSDART00000190077

chr4_+_20536120 0.02 ENSDART00000125685
zmp:0000000650
chr2_+_23130389 0.02 ENSDART00000142834
si:dkey-218h11.6
chr5_-_3118346 0.02 ENSDART00000167554
heat shock transcription factor family member 5
chr10_+_40700311 0.02 ENSDART00000157650
ENSDART00000138342
trace amine associated receptor 19n
chr23_+_42336084 0.02 ENSDART00000158959
ENSDART00000161812
cytochrome P450, family 2, subfamily AA, polypeptide 7
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr2_-_37478418 0.02 ENSDART00000146103
death-associated protein kinase 3
chr12_+_46582168 0.02 ENSDART00000189402
Usher syndrome 1Gb (autosomal recessive)
chr7_+_36552725 0.02 ENSDART00000173682
chromodomain helicase DNA binding protein 9
chr1_-_11616295 0.02 ENSDART00000188891
si:dkey-26i13.5
chr2_+_18017000 0.02 ENSDART00000186877

chr24_+_14451404 0.02 ENSDART00000123674
ENSDART00000066720
PR domain containing 14
chr3_+_52078798 0.02 ENSDART00000156882
si:dkey-88e12.3
chr24_-_25030173 0.02 ENSDART00000126395
ENSDART00000019350
nucleoporin 58
chr11_-_14924138 0.02 ENSDART00000168348
si:dkey-6d5.1
chr1_-_11616142 0.02 ENSDART00000131668
si:dkey-26i13.5
chr16_+_35343493 0.02 ENSDART00000171269
si:dkey-34d22.1
chr17_+_28670132 0.02 ENSDART00000076344
ENSDART00000164981
ENSDART00000182851
HECT domain containing 1
chr3_+_34180835 0.02 ENSDART00000055252
translocase of inner mitochondrial membrane 29
chr5_+_65946222 0.02 ENSDART00000190969
ENSDART00000161578
myomaker, myoblast fusion factor
chr16_+_24972826 0.02 ENSDART00000063115
formyl peptide receptor 1
chr21_+_22828500 0.02 ENSDART00000151109
si:rp71-1p14.7
chr17_-_5610514 0.02 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr5_-_68795063 0.02 ENSDART00000016307
hairy-related 1
chr7_-_30932094 0.02 ENSDART00000057677
telomere repeat binding bouquet formation protein 2
chr9_-_3834686 0.02 ENSDART00000141492
myosin IIIB
chr11_-_7147540 0.02 ENSDART00000143942
bone morphogenetic protein 7a
chr6_-_43792179 0.02 ENSDART00000160849
forkhead box P1b
chr25_-_35127617 0.02 ENSDART00000125128
histone cluster 1 H2A family member 4
chr1_-_45616470 0.02 ENSDART00000150165
activating transcription factor 7 interacting protein
chr5_+_1933131 0.02 ENSDART00000061693
si:ch73-55i23.1
chr18_+_10689772 0.02 ENSDART00000126441
leptin a
chr22_+_18319230 0.02 ENSDART00000184747
ENSDART00000184649
GATA zinc finger domain containing 2Ab
chr4_-_53047883 0.02 ENSDART00000157496
si:dkey-201g16.5
chr4_-_64123545 0.02 ENSDART00000170040

chr6_+_52859495 0.02 ENSDART00000103135
odorant receptor, family H, subfamily 134, member 1
chr15_+_38299563 0.02 ENSDART00000099375
si:dkey-24p1.6
chr1_-_11606903 0.02 ENSDART00000136093
si:dkey-26i13.6
chr18_+_20560442 0.02 ENSDART00000151990
WEE1 homolog 2 (S. pombe)
chr17_-_50472864 0.02 ENSDART00000161066
ENSDART00000156963
si:ch211-235i11.3
chr24_-_16917086 0.02 ENSDART00000110715
carboxymethylenebutenolidase homolog (Pseudomonas)
chr19_-_32600138 0.02 ENSDART00000052101
zgc:91944
chr17_+_8175998 0.02 ENSDART00000131200
myc target 1b
chr11_+_45422206 0.02 ENSDART00000182548
HRAS-like suppressor
chr25_+_28158352 0.02 ENSDART00000151854
Ca++-dependent secretion activator 2
chr14_-_10617127 0.02 ENSDART00000154299
si:dkey-92i17.2
chr8_-_53044300 0.02 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr1_+_56972616 0.01 ENSDART00000152812
si:ch211-1f22.11
chr7_-_32021853 0.01 ENSDART00000134521
kinesin family member 18A
chr2_-_51388214 0.01 ENSDART00000163838
si:dkeyp-104b3.18
chr5_-_26118855 0.01 ENSDART00000009028
elastase 3 like
chr7_-_21928826 0.01 ENSDART00000088043
si:dkey-85k7.11
chr3_+_9588705 0.01 ENSDART00000172543
ENSDART00000104875
TNF receptor-associated protein 1
chr4_+_42604252 0.01 ENSDART00000184850

chr1_-_11607062 0.01 ENSDART00000158253
si:dkey-26i13.6
chr20_+_41801913 0.01 ENSDART00000139805
minichromosome maintenance 9 homologous recombination repair factor
chr21_-_293146 0.01 ENSDART00000157781
plasminogen receptor, C-terminal lysine transmembrane protein
chr16_-_29405009 0.01 ENSDART00000149289
toll-like receptor 18
chr1_+_6357059 0.01 ENSDART00000166620
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2b
chr16_+_26747766 0.01 ENSDART00000183257
RAD54 homolog B (S. cerevisiae)
chr7_+_3597413 0.01 ENSDART00000064281
si:dkey-192d15.2
chr5_+_56119975 0.01 ENSDART00000083137
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr18_+_48953963 0.01 ENSDART00000158104
SH3KBP1 binding protein 1
chr15_+_38299385 0.01 ENSDART00000142403
si:dkey-24p1.6
chr8_-_8426504 0.01 ENSDART00000191686
ENSDART00000181523
cyclin-dependent kinase 16
chr22_-_34995333 0.01 ENSDART00000110900
Kv channel interacting protein 2
chr2_-_56757069 0.01 ENSDART00000164461
histocompatibility (minor) HA-1 a
chr24_+_19415124 0.01 ENSDART00000186931
sulfatase 1
chr6_+_30091811 0.01 ENSDART00000088403
melanotransferrin
chr7_-_52558495 0.01 ENSDART00000138263
ENSDART00000009938
ENSDART00000174292
ENSDART00000174218
ENSDART00000174335
transcription factor 12
chr18_+_33100606 0.01 ENSDART00000003907
si:ch211-229c8.13
chr21_+_26539157 0.01 ENSDART00000021121
syntaxin 5A, like
chr1_-_10347198 0.01 ENSDART00000109141
ENSDART00000152565
si:ch211-243g6.3
chr1_-_45616242 0.01 ENSDART00000150066
activating transcription factor 7 interacting protein
chr14_+_23158021 0.01 ENSDART00000084664
ecto-NOX disulfide-thiol exchanger 2
chr2_-_43850637 0.01 ENSDART00000136077
zinc finger E-box binding homeobox 1a
chr17_-_50436199 0.01 ENSDART00000156494
si:ch211-235i11.6
chr21_-_28640316 0.01 ENSDART00000128237
neuregulin 2a
chr16_+_46410520 0.01 ENSDART00000131072
rapunzel 2
chr7_+_26006819 0.01 ENSDART00000112908
proline, glutamate and leucine rich protein 1
chr17_-_50454957 0.01 ENSDART00000171616
ENSDART00000075195
si:ch211-235i11.7
chr11_-_22303678 0.01 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr6_+_46259950 0.01 ENSDART00000032326
zgc:162324
chr17_-_31082381 0.01 ENSDART00000186930
ENSDART00000193865
echinoderm microtubule associated protein like 1
chr1_-_37383741 0.01 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
secretory calcium-binding phosphoprotein 1
chr3_+_33918510 0.01 ENSDART00000055248
alkB homolog 7
chr16_-_8663493 0.01 ENSDART00000014944
ENSDART00000181533
ENSDART00000182721
ENSDART00000162988
cordon-bleu WH2 repeat protein
chr15_-_2973368 0.01 ENSDART00000163131
zgc:153184
chr12_-_28799642 0.01 ENSDART00000066303
mitochondrial ribosomal protein L10
chr24_+_19414561 0.01 ENSDART00000193157
sulfatase 1
chr5_+_38726854 0.01 ENSDART00000138484
ENSDART00000142867
si:dkey-58f10.7
chr22_+_18319666 0.01 ENSDART00000033103
GATA zinc finger domain containing 2Ab
chr12_-_4424424 0.01 ENSDART00000152314
si:ch211-173d10.1
chr14_-_6402769 0.01 ENSDART00000121552
solute carrier family 44 (choline transporter), member 1b
chr22_+_7486867 0.01 ENSDART00000034586
zgc:112302
chr13_+_48358467 0.01 ENSDART00000171080
ENSDART00000162531
mutS homolog 6 (E. coli)
chr4_-_49133107 0.01 ENSDART00000150806
zinc finger protein 1146
chr4_-_77377596 0.01 ENSDART00000186068
solute carrier organic anion transporter family, member 1E1
chr15_+_29276508 0.01 ENSDART00000170537
ENSDART00000126559
RAP1 GTPase activating protein 2a
chr12_-_48188928 0.01 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr4_-_12781182 0.01 ENSDART00000058020
helicase (DNA) B
chr23_+_31405497 0.01 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr22_-_17499513 0.00 ENSDART00000105460
si:ch211-197g15.6
chr9_+_11587629 0.00 ENSDART00000102508
ENSDART00000146585
si:dkey-69o16.5
chr9_-_12574473 0.00 ENSDART00000191372
ENSDART00000193667
insulin-like growth factor 2 mRNA binding protein 2a
chr8_-_36125849 0.00 ENSDART00000159581

chr22_-_5933844 0.00 ENSDART00000163370
ENSDART00000189331
si:rp71-36a1.2
chr21_-_17037907 0.00 ENSDART00000101263
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr6_+_54221654 0.00 ENSDART00000128456
protein kinase C and casein kinase substrate in neurons 1b
chr3_+_52684556 0.00 ENSDART00000139037
6-phosphogluconolactonase
chr5_+_25733774 0.00 ENSDART00000137088
ENSDART00000098467
abhydrolase domain containing 17B
chr2_-_37797577 0.00 ENSDART00000110781
nuclear factor of activated T cells 4
chr5_-_62940851 0.00 ENSDART00000137052
sperm antigen with calponin homology and coiled-coil domains 1
chr2_-_24317240 0.00 ENSDART00000078975
tRNA selenocysteine 1 associated protein 1b
chr7_+_69449814 0.00 ENSDART00000109644
CTD nuclear envelope phosphatase 1b
chr1_+_19708508 0.00 ENSDART00000054581
ENSDART00000131206
membrane-associated ring finger (C3HC4) 1
chr14_+_45350008 0.00 ENSDART00000025749
tetratricopeptide repeat domain 9C
chr5_-_51998708 0.00 ENSDART00000097194
serine incorporator 5
chr12_-_44122412 0.00 ENSDART00000169094
si:ch73-329n5.3
chr15_+_791220 0.00 ENSDART00000136137
si:dkey-7i4.1
chr24_+_5829265 0.00 ENSDART00000155242
si:ch211-157j23.5

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo3b+foxo6a+foxo6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.0 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.0 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)