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PRJNA207719: Tissue specific transcriptome profiling

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Results for gata1b+gata2a

Z-value: 2.60

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Transcription factors associated with gata1b+gata2a

Gene Symbol Gene ID Gene Info
gata1b
ENSDARG00000059130 GATA binding protein 1b
gata2a
ENSDARG00000059327 GATA binding protein 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gata1bdr11_v1_chr8_-_7474997_7474997-0.761.3e-01Click!
gata2adr11_v1_chr11_-_3860199_3860199-0.276.7e-01Click!

Activity profile of gata1b+gata2a motif

Sorted Z-values of gata1b+gata2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_7379728 4.71 ENSDART00000012194
gata5
GATA binding protein 5
chr16_+_12611362 3.81 ENSDART00000055160
il11a
interleukin 11a
chr25_-_28674739 3.78 ENSDART00000067073
lrrc10
leucine rich repeat containing 10
chr2_-_24289641 3.35 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myh7l
myosin heavy chain 7-like
chr5_-_64168415 3.14 ENSDART00000048395
cmlc1
cardiac myosin light chain-1
chr21_-_40880317 2.68 ENSDART00000100054
ENSDART00000137696
elnb
elastin b
chr2_+_4207209 2.57 ENSDART00000157903
ENSDART00000166476
gata6
GATA binding protein 6
chr8_-_18537866 2.57 ENSDART00000148802
ENSDART00000148962
ENSDART00000149506
nexn
nexilin (F actin binding protein)
chr20_+_40150612 2.04 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
trdn
triadin
chr5_+_21211135 2.03 ENSDART00000088492
bmp10
bone morphogenetic protein 10
chr3_+_55105066 2.02 ENSDART00000110848
si:ch211-5k11.8
si:ch211-5k11.8
chr7_-_73752955 1.97 ENSDART00000171254
ENSDART00000009888
casq1b
calsequestrin 1b
chr2_-_51794472 1.94 ENSDART00000186652
BX908782.3

chr8_-_40464935 1.88 ENSDART00000040013
myl7
myosin, light chain 7, regulatory
chr7_-_41858513 1.88 ENSDART00000109918
mylk3
myosin light chain kinase 3
chr23_-_5685023 1.85 ENSDART00000148680
ENSDART00000149365
tnnt2a
troponin T type 2a (cardiac)
chr13_+_22480496 1.85 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr7_-_41851605 1.72 ENSDART00000142981
mylk3
myosin light chain kinase 3
chr13_+_22479988 1.68 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr18_+_18000695 1.52 ENSDART00000146898
si:ch211-212o1.2
si:ch211-212o1.2
chr8_-_50287949 1.51 ENSDART00000023639
nkx2.7
NK2 transcription factor related 7
chr20_+_23625387 1.48 ENSDART00000147945
ENSDART00000150497
palld
palladin, cytoskeletal associated protein
chr20_+_33981946 1.48 ENSDART00000131775
si:dkey-51e6.1
si:dkey-51e6.1
chr5_+_23151169 1.48 ENSDART00000125638
tbx5b
T-box 5b
chr16_+_26449615 1.43 ENSDART00000039746
epb41b
erythrocyte membrane protein band 4.1b
chr19_+_37509638 1.42 ENSDART00000139999
si:ch211-250g4.3
si:ch211-250g4.3
chr24_-_39858710 1.38 ENSDART00000134251
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr19_+_46158078 1.29 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr19_+_8606883 1.28 ENSDART00000054469
ENSDART00000185264
s100a10a
S100 calcium binding protein A10a
chr24_+_26276805 1.23 ENSDART00000089749
adipoqa
adiponectin, C1Q and collagen domain containing, a
chr3_+_55100045 1.23 ENSDART00000113098
hbaa1
hemoglobin, alpha adult 1
chr7_+_12835048 1.23 ENSDART00000016465
cx36.7
connexin 36.7
chr18_-_16795262 1.19 ENSDART00000048722
ampd3b
adenosine monophosphate deaminase 3b
chr10_-_17484762 1.18 ENSDART00000137905
ENSDART00000007961
nt5c2l1
5'-nucleotidase, cytosolic II, like 1
chr13_+_10945337 1.00 ENSDART00000091845
abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr24_-_2843107 0.99 ENSDART00000165290
cyb5a
cytochrome b5 type A (microsomal)
chr2_-_38261272 0.98 ENSDART00000143743
si:ch211-14a17.10
si:ch211-14a17.10
chr20_-_25533739 0.98 ENSDART00000063064
cyp2ad6
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr16_-_24945337 0.96 ENSDART00000154004
has1
hyaluronan synthase 1
chr22_+_5120033 0.95 ENSDART00000169200
mibp
muscle-specific beta 1 integrin binding protein
chr15_-_43164591 0.93 ENSDART00000171305
ap1s3a
adaptor-related protein complex 1, sigma 3 subunit, a
chr7_+_44445595 0.93 ENSDART00000108766
cdh5
cadherin 5
chr20_-_26066020 0.92 ENSDART00000078559
myct1a
myc target 1a
chr21_+_19547806 0.91 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
rai14
retinoic acid induced 14
chr11_-_1400507 0.90 ENSDART00000173029
ENSDART00000172953
ENSDART00000111140
rpl29
ribosomal protein L29
chr11_-_25418856 0.89 ENSDART00000013714
gata1a
GATA binding protein 1a
chr8_+_31872992 0.89 ENSDART00000146933
c7a
complement component 7a
chr20_-_33705044 0.87 ENSDART00000166573
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr4_+_1530287 0.87 ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr24_-_12958668 0.86 ENSDART00000178982
FITM1 (1 of many)
Danio rerio fat storage inducing transmembrane protein 1 (LOC792443), mRNA.
chr20_+_33875256 0.85 ENSDART00000002554
rxrgb
retinoid X receptor, gamma b
chr17_-_14671098 0.84 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr22_+_5118361 0.82 ENSDART00000168371
ENSDART00000170222
ENSDART00000158846
mibp
muscle-specific beta 1 integrin binding protein
chr16_-_17300030 0.82 ENSDART00000149267
kel
Kell blood group, metallo-endopeptidase
chr18_-_6803424 0.81 ENSDART00000142647
si:dkey-266m15.5
si:dkey-266m15.5
chr21_-_11834452 0.80 ENSDART00000081652
rfesd
Rieske (Fe-S) domain containing
chr16_-_24815091 0.79 ENSDART00000154269
ENSDART00000131025
kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr18_-_42830563 0.79 ENSDART00000191488
ttc36
tetratricopeptide repeat domain 36
chr21_-_25756119 0.78 ENSDART00000002341
cldnc
claudin c
chr13_-_10945288 0.77 ENSDART00000114315
ENSDART00000164667
ENSDART00000159482
abcg8
ATP-binding cassette, sub-family G (WHITE), member 8
chr7_+_35075847 0.77 ENSDART00000193469
ENSDART00000037346
ctrb1
chymotrypsinogen B1
chr12_+_23850661 0.76 ENSDART00000152921
svila
supervillin a
chr19_+_20778011 0.76 ENSDART00000024208
nutf2l
nuclear transport factor 2, like
chr11_+_31285127 0.74 ENSDART00000160154
si:dkey-238i5.2
si:dkey-238i5.2
chr23_+_25856541 0.74 ENSDART00000145426
ENSDART00000028236
hnf4a
hepatocyte nuclear factor 4, alpha
chr5_+_15203421 0.73 ENSDART00000040826
tbx1
T-box 1
chr1_+_36674584 0.72 ENSDART00000186772
ENSDART00000192274
ednraa
endothelin receptor type Aa
chr1_-_9109699 0.70 ENSDART00000147833
vap
vascular associated protein
chr18_+_48428126 0.70 ENSDART00000137978
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr22_-_36856405 0.68 ENSDART00000029588
kng1
kininogen 1
chr8_+_37700090 0.68 ENSDART00000187885
ENSDART00000127633
adrb3a
adrenoceptor beta 3a
chr7_-_15252540 0.68 ENSDART00000173072
ENSDART00000125258
si:dkey-172h23.2
si:dkey-172h23.2
chr10_+_26612321 0.68 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr15_+_26600611 0.66 ENSDART00000155352
slc47a3
solute carrier family 47 (multidrug and toxin extrusion), member 3
chr1_-_38816685 0.66 ENSDART00000075230
asb5b
ankyrin repeat and SOCS box containing 5b
chr6_-_609880 0.65 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lgals2b
lectin, galactoside-binding, soluble, 2b
chr20_-_33704753 0.64 ENSDART00000157427
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr7_+_9904627 0.63 ENSDART00000172824
cers3a
ceramide synthase 3a
chr5_-_51166025 0.61 ENSDART00000097471
card9
caspase recruitment domain family, member 9
chr12_-_32421046 0.60 ENSDART00000075567
enpp7.1
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 1
chr6_-_49078263 0.60 ENSDART00000032982
slc5a8l
solute carrier family 5 (iodide transporter), member 8-like
chr7_+_17120811 0.60 ENSDART00000147140
prmt3
protein arginine methyltransferase 3
chr19_-_46777963 0.59 ENSDART00000046857
abrab
actin binding Rho activating protein b
chr21_+_12010505 0.58 ENSDART00000123522
aqp7
aquaporin 7
chr3_-_34547000 0.58 ENSDART00000166623
sept9a
septin 9a
chr14_+_26546175 0.57 ENSDART00000105932
si:dkeyp-110e4.11
si:dkeyp-110e4.11
chr24_+_19518570 0.56 ENSDART00000056081
sulf1
sulfatase 1
chr3_+_16762483 0.56 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr20_+_25879826 0.55 ENSDART00000018519
zgc:153896
zgc:153896
chr24_+_19518303 0.55 ENSDART00000027022
ENSDART00000056080
sulf1
sulfatase 1
chr13_+_835390 0.55 ENSDART00000171329
gsta.1
glutathione S-transferase, alpha tandem duplicate 1
chr17_+_39242437 0.54 ENSDART00000156138
ENSDART00000128863
zgc:174356
zgc:174356
chr15_-_21877726 0.53 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr8_+_26059677 0.53 ENSDART00000009178
impdh2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr13_-_25774183 0.53 ENSDART00000046981
pdlim1
PDZ and LIM domain 1 (elfin)
chr10_+_10801719 0.52 ENSDART00000193648
ambp
alpha-1-microglobulin/bikunin precursor
chr5_-_42272517 0.52 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr13_+_24851102 0.50 ENSDART00000187637
si:dkey-24f15.2
si:dkey-24f15.2
chr9_+_343062 0.50 ENSDART00000164012
ENSDART00000164365
bpifcl
BPI fold containing family C, like
chr17_+_34206167 0.49 ENSDART00000136167
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr10_+_10801564 0.49 ENSDART00000027026
ambp
alpha-1-microglobulin/bikunin precursor
chr18_+_48428713 0.49 ENSDART00000076861
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr8_+_6576940 0.48 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr18_+_33550667 0.48 ENSDART00000141246
ENSDART00000136070
si:dkey-47k20.1
si:dkey-47k20.1
chr11_-_28614608 0.46 ENSDART00000065853
dhrs3b
dehydrogenase/reductase (SDR family) member 3b
chr23_+_36115541 0.45 ENSDART00000130090
hoxc6a
homeobox C6a
chr13_+_844150 0.45 ENSDART00000058260
gsta.1
glutathione S-transferase, alpha tandem duplicate 1
chr23_-_35483163 0.45 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
fbxo25
F-box protein 25
chr5_-_8817841 0.44 ENSDART00000170921
fgf10b
fibroblast growth factor 10b
chr14_+_30568961 0.44 ENSDART00000184303
mrpl11
mitochondrial ribosomal protein L11
chr17_+_8175998 0.44 ENSDART00000131200
myct1b
myc target 1b
chr2_+_39021282 0.43 ENSDART00000056577
RBP1 (1 of many)
si:ch211-119o8.7
chr6_-_30485009 0.43 ENSDART00000025698
zgc:153311
zgc:153311
chr9_-_42871756 0.42 ENSDART00000191396
ttn.1
titin, tandem duplicate 1
chr25_-_35102781 0.42 ENSDART00000180881
ENSDART00000153747
si:dkey-108k21.24
si:dkey-108k21.24
chr6_-_40697585 0.42 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr13_-_37103126 0.40 ENSDART00000135935
syne2b
spectrin repeat containing, nuclear envelope 2b
chr8_+_23485079 0.40 ENSDART00000026316
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr12_-_29301022 0.40 ENSDART00000187826
sh2d4bb
SH2 domain containing 4Bb
chr25_+_18564266 0.39 ENSDART00000172338
cav1
caveolin 1
chr5_+_26248380 0.39 ENSDART00000079049
si:ch211-214j8.1
si:ch211-214j8.1
chr14_+_32839535 0.38 ENSDART00000168975
arr3b
arrestin 3b, retinal (X-arrestin)
chr14_+_2487672 0.38 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr14_+_29780113 0.38 ENSDART00000173195
zgc:153146
zgc:153146
chr3_+_50602866 0.38 ENSDART00000190069
ENSDART00000153921
gsg1l2a
gsg1-like 2a
chr13_+_24679674 0.38 ENSDART00000033090
ENSDART00000139854
zgc:66426
zgc:66426
chr23_+_25708787 0.37 ENSDART00000060059
rbms2b
RNA binding motif, single stranded interacting protein 2b
chr16_-_24668620 0.37 ENSDART00000012807
pon3.2
paraoxonase 3, tandem duplicate 2
chr24_-_25691020 0.37 ENSDART00000015391
chrnd
cholinergic receptor, nicotinic, delta (muscle)
chr12_-_20350629 0.37 ENSDART00000066384
hbbe2
hemoglobin beta embryonic-2
chr8_-_40327397 0.37 ENSDART00000074125
aplnra
apelin receptor a
chr24_+_2843268 0.36 ENSDART00000170529
si:ch211-152c8.2
si:ch211-152c8.2
chr5_-_68795063 0.36 ENSDART00000016307
her1
hairy-related 1
chr4_-_20511595 0.36 ENSDART00000185806
rassf8b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b
chr11_-_34577034 0.35 ENSDART00000133302
ENSDART00000184367
pfkfb4a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr6_-_39275793 0.34 ENSDART00000180477
ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr14_+_23184517 0.34 ENSDART00000181410
enox2
ecto-NOX disulfide-thiol exchanger 2
chr3_-_26204867 0.33 ENSDART00000103748
gdpd3a
glycerophosphodiester phosphodiesterase domain containing 3a
chr15_+_29709382 0.33 ENSDART00000099956
nrip1a
nuclear receptor interacting protein 1a
chr13_-_40282770 0.32 ENSDART00000140875
zgc:123010
zgc:123010
chr12_+_6391243 0.32 ENSDART00000152765
prkg1b
protein kinase, cGMP-dependent, type Ib
chr13_-_23031803 0.32 ENSDART00000056523
hkdc1
hexokinase domain containing 1
chr1_+_26667872 0.32 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemgn
hemogen
chr24_+_14801844 0.31 ENSDART00000141620
pi15a
peptidase inhibitor 15a
chr20_-_35554451 0.31 ENSDART00000189085
adgrf7
adhesion G protein-coupled receptor F7
chr16_-_5612480 0.31 ENSDART00000157944
CR848788.1

chr20_+_1329509 0.31 ENSDART00000017791
ENSDART00000136669
tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr22_+_30112390 0.31 ENSDART00000191715
add3a
adducin 3 (gamma) a
chr2_+_38261748 0.30 ENSDART00000076478
dhrs1
dehydrogenase/reductase (SDR family) member 1
chr5_-_37103487 0.30 ENSDART00000149211
il13ra2
interleukin 13 receptor, alpha 2
chr9_-_45149695 0.30 ENSDART00000162033
CU467837.1

chr5_-_26247973 0.29 ENSDART00000098527
erap1b
endoplasmic reticulum aminopeptidase 1b
chr19_+_43523690 0.29 ENSDART00000113031
wasf2
WAS protein family, member 2
chr3_-_33395233 0.29 ENSDART00000167349
si:dkey-283b1.6
si:dkey-283b1.6
chr13_+_24263049 0.29 ENSDART00000135992
ENSDART00000088005
abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr7_-_51102479 0.28 ENSDART00000174023
col4a6
collagen, type IV, alpha 6
chr1_+_9954489 0.28 ENSDART00000005895
ENSDART00000183003
pdia2
protein disulfide isomerase family A, member 2
chr3_+_28502419 0.28 ENSDART00000151081
sept12
septin 12
chr6_+_58915889 0.28 ENSDART00000083628
ddit3
DNA-damage-inducible transcript 3
chr14_+_21686207 0.28 ENSDART00000034438
ran
RAN, member RAS oncogene family
chr7_-_68419830 0.27 ENSDART00000191606
CU468723.2

chr25_+_35134393 0.26 ENSDART00000185379
CR762436.2

chr7_+_5976613 0.26 ENSDART00000173105
si:dkey-23a13.21
si:dkey-23a13.21
chr25_-_7974494 0.26 ENSDART00000171446
hal
histidine ammonia-lyase
chr21_+_19648814 0.26 ENSDART00000048581
fgf10a
fibroblast growth factor 10a
chr7_+_34290051 0.26 ENSDART00000123498
fibinb
fin bud initiation factor b
chr9_+_2522797 0.25 ENSDART00000186786
ENSDART00000147034
gpr155a
G protein-coupled receptor 155a
chr17_-_26867725 0.25 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr16_-_30564319 0.25 ENSDART00000145087
lmna
lamin A
chr24_-_21258945 0.25 ENSDART00000111025
boc
BOC cell adhesion associated, oncogene regulated
chr12_-_23658888 0.25 ENSDART00000088319
map3k8
mitogen-activated protein kinase kinase kinase 8
chr4_+_7508316 0.25 ENSDART00000170924
ENSDART00000170933
ENSDART00000164985
ENSDART00000167571
ENSDART00000158843
ENSDART00000158999
tnnt2e
troponin T2e, cardiac
chr14_+_17382803 0.24 ENSDART00000040383
si:ch211-255i20.3
si:ch211-255i20.3
chr23_-_33709964 0.23 ENSDART00000143333
ENSDART00000130338
pou6f1
POU class 6 homeobox 1
chr4_-_20118468 0.23 ENSDART00000078587
si:dkey-159a18.1
si:dkey-159a18.1
chr10_+_19525839 0.23 ENSDART00000162912
ENSDART00000158512
vsig8a
V-set and immunoglobulin domain containing 8a
chr22_-_11626014 0.23 ENSDART00000063133
ENSDART00000160085
gcga
glucagon a
chr18_+_23249519 0.22 ENSDART00000005740
ENSDART00000147446
ENSDART00000124818
mef2aa
myocyte enhancer factor 2aa
chr4_+_16725960 0.22 ENSDART00000034441
tcp11l2
t-complex 11, testis-specific-like 2
chr3_+_24275597 0.22 ENSDART00000183926
ENSDART00000169765
pdgfbb
platelet-derived growth factor beta polypeptide b
chr14_-_41556720 0.22 ENSDART00000149244
itga6l
integrin, alpha 6, like
chr22_+_15336752 0.22 ENSDART00000139070
sult3st2
sulfotransferase family 3, cytosolic sulfotransferase 2
chr14_+_36738069 0.22 ENSDART00000105590
tdo2a
tryptophan 2,3-dioxygenase a
chr7_+_29863548 0.21 ENSDART00000136555
ENSDART00000134068
tln2a
talin 2a
chr10_+_13209580 0.21 ENSDART00000000887
ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr8_-_40555340 0.20 ENSDART00000163348
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr1_-_17570013 0.20 ENSDART00000146946
acsl1a
acyl-CoA synthetase long chain family member 1a
chr12_-_20665164 0.20 ENSDART00000105352
gip
gastric inhibitory polypeptide
chr19_-_3381422 0.19 ENSDART00000105146
edn1
endothelin 1
chr23_-_23401305 0.19 ENSDART00000078936
her9
hairy-related 9
chr16_+_13424534 0.19 ENSDART00000114944
zgc:101640
zgc:101640
chr3_+_24275766 0.19 ENSDART00000055607
pdgfbb
platelet-derived growth factor beta polypeptide b
chr5_-_66301142 0.19 ENSDART00000067541
prlrb
prolactin receptor b
chr3_+_40809892 0.19 ENSDART00000190803
arpc1b
actin related protein 2/3 complex, subunit 1B
chr14_-_25949951 0.18 ENSDART00000141304
sparc
secreted protein, acidic, cysteine-rich (osteonectin)
chr8_+_20393250 0.18 ENSDART00000015038
zap70
zeta chain of T cell receptor associated protein kinase 70
chr15_-_2903475 0.18 ENSDART00000043226
guca1c
guanylate cyclase activator 1C
chr14_-_28052474 0.17 ENSDART00000172948
ENSDART00000135337
TSC22D3 (1 of many)
zgc:64189
si:ch211-220e11.3
zgc:64189
chr6_+_8176486 0.17 ENSDART00000193308
nfil3-5
nuclear factor, interleukin 3 regulated, member 5
chr6_+_51932563 0.17 ENSDART00000181778
angpt4
angiopoietin 4

Network of associatons between targets according to the STRING database.

First level regulatory network of gata1b+gata2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.3 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
1.4 8.6 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.7 2.0 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.5 1.5 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.5 1.5 GO:0003218 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.5 1.9 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.4 2.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 1.0 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 4.2 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.2 0.7 GO:0003156 regulation of organ formation(GO:0003156)
0.2 0.9 GO:0030224 monocyte differentiation(GO:0030224)
0.2 3.6 GO:0015671 oxygen transport(GO:0015671)
0.2 0.7 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.2 0.9 GO:0001955 blood vessel maturation(GO:0001955) regulation of establishment of cell polarity(GO:2000114)
0.2 1.5 GO:0003207 cardiac chamber formation(GO:0003207)
0.1 1.1 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.4 GO:1903392 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.1 0.7 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.5 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.7 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.5 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.1 0.7 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047)
0.1 0.3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.1 0.3 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.2 GO:0032264 IMP salvage(GO:0032264)
0.1 0.2 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 1.5 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.1 0.3 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.1 0.3 GO:0007624 ultradian rhythm(GO:0007624)
0.1 1.8 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 0.2 GO:0060585 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 1.4 GO:1990798 pancreas regeneration(GO:1990798)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 1.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.2 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:0090342 regulation of cell aging(GO:0090342)
0.0 1.9 GO:0060840 artery development(GO:0060840)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.4 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.6 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.9 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.4 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) G-protein coupled receptor internalization(GO:0002031) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.8 GO:0032526 response to retinoic acid(GO:0032526)
0.0 3.2 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.9 GO:0019835 cytolysis(GO:0019835)
0.0 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 4.1 GO:0001756 somitogenesis(GO:0001756)
0.0 1.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 1.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.0 0.6 GO:0035775 pronephric glomerulus morphogenesis(GO:0035775)
0.0 1.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.2 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 3.8 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 1.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0090050 positive regulation of blood vessel endothelial cell migration(GO:0043536) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.9 GO:0002181 cytoplasmic translation(GO:0002181)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 2.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.4 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 4.1 GO:0031941 filamentous actin(GO:0031941)
0.1 0.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 2.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 9.2 GO:0030017 sarcomere(GO:0030017)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.1 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 1.5 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.3 3.6 GO:0031720 haptoglobin binding(GO:0031720)
0.3 1.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 3.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 1.8 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.2 4.1 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 2.1 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 1.5 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.2 0.7 GO:0051380 norepinephrine binding(GO:0051380)
0.1 1.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.3 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.4 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.4 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.6 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.6 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.4 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.3 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 5.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0030250 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 1.0 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 1.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 3.5 GO:0003774 motor activity(GO:0003774)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.1 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 7.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors