ISMARA results: gata1b+gata2a

Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation

Downloads

Results for gata1b+gata2a

Z-value: 2.60

Motif logo

Transcription factors associated with gata1b+gata2a

Gene Symbol	Gene ID	Gene Info
gata1b NCBI UniProt	ENSDARG00000059130	GATA binding protein 1b
gata2a NCBI UniProt	ENSDARG00000059327	GATA binding protein 2a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
gata1b	dr11_v1_chr8_-_7474997_7474997	-0.76	1.3e-01	Click!
gata2a	dr11_v1_chr11_-_3860199_3860199	-0.27	6.7e-01	Click!

Activity profile of gata1b+gata2a motif

Sorted Z-values of gata1b+gata2a motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr23_+_7379728 Show fit	4.71	ENSDART00000012194	gata5 NCBI UniProt Show fit	GATA binding protein 5
chr16_+_12611362 Show fit	3.81	ENSDART00000055160	il11a NCBI UniProt Show fit	interleukin 11a
chr25_-_28674739 Show fit	3.78	ENSDART00000067073	lrrc10 NCBI UniProt Show fit	leucine rich repeat containing 10
chr2_-_24289641 Show fit	3.35	ENSDART00000128784 ENSDART00000123565 ENSDART00000141922 ENSDART00000184550 ENSDART00000191469	myh7l NCBI UniProt Show fit	myosin heavy chain 7-like
chr5_-_64168415 Show fit	3.14	ENSDART00000048395	cmlc1 NCBI UniProt Show fit	cardiac myosin light chain-1
chr21_-_40880317 Show fit	2.68	ENSDART00000100054 ENSDART00000137696	elnb NCBI UniProt Show fit	elastin b
chr2_+_4207209 Show fit	2.57	ENSDART00000157903 ENSDART00000166476	gata6 NCBI UniProt Show fit	GATA binding protein 6
chr8_-_18537866 Show fit	2.57	ENSDART00000148802 ENSDART00000148962 ENSDART00000149506	nexn NCBI UniProt Show fit	nexilin (F actin binding protein)
chr20_+_40150612 Show fit	2.04	ENSDART00000143680 ENSDART00000109681 ENSDART00000101041 ENSDART00000121818	trdn NCBI UniProt Show fit	triadin
chr5_+_21211135 Show fit	2.03	ENSDART00000088492	bmp10 NCBI UniProt Show fit	bone morphogenetic protein 10

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of gata1b+gata2a

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	8.6	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
1.5	7.3	GO:0001773	myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.3	4.2	GO:0061026	cardiac muscle tissue regeneration(GO:0061026)
0.0	4.1	GO:0001756	somitogenesis(GO:0001756)
0.0	3.8	GO:0008284	positive regulation of cell proliferation(GO:0008284)
0.2	3.6	GO:0015671	oxygen transport(GO:0015671)
0.0	3.2	GO:0071466	cellular response to xenobiotic stimulus(GO:0071466)
0.4	2.6	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.7	2.0	GO:0014809	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.5	1.9	GO:0003228	atrial cardiac muscle tissue development(GO:0003228)

Showing 1 to 10 of 80 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	9.2	GO:0030017	sarcomere(GO:0030017)
0.1	4.1	GO:0031941	filamentous actin(GO:0031941)
0.3	3.6	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	3.5	GO:0016459	myosin complex(GO:0016459)
0.3	2.0	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	2.0	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	1.1	GO:0005795	Golgi stack(GO:0005795)
0.0	1.1	GO:0048475	membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1	0.9	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.9	GO:0016342	catenin complex(GO:0016342)

Showing 1 to 10 of 23 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	5.2	GO:0005125	cytokine activity(GO:0005125)
0.2	4.1	GO:0051393	muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.3	3.6	GO:0031720	haptoglobin binding(GO:0031720)
0.3	3.6	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	3.5	GO:0003774	motor activity(GO:0003774)
0.0	2.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.2	2.1	GO:0030172	troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0	2.1	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.3	1.8	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262)
0.4	1.5	GO:0101006	protein histidine phosphatase activity(GO:0101006)

Showing 1 to 10 of 72 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	2.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.7	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway

Showing 1 to 10 of 13 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.8	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	1.0	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.9	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	0.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.8	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels

Showing 1 to 10 of 26 entries

Results for gata1b+gata2a

Z-value: 2.60

Motif logo

Transcription factors associated with gata1b+gata2a

Activity-expression correlation:

Activity profile of gata1b+gata2a motif

Sorted Z-values of gata1b+gata2a motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of gata1b+gata2a

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: