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PRJNA207719: Tissue specific transcriptome profiling

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Results for gsx2+pnx

Z-value: 1.09

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Transcription factors associated with gsx2+pnx

Gene Symbol Gene ID Gene Info
pnx
ENSDARG00000025899 posterior neuron-specific homeobox
gsx2
ENSDARG00000043322 GS homeobox 2
gsx2
ENSDARG00000116417 GS homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pnxdr11_v1_chr10_+_2799285_27992850.652.4e-01Click!
gsx2dr11_v1_chr20_-_22484621_22484621-0.098.9e-01Click!

Activity profile of gsx2+pnx motif

Sorted Z-values of gsx2+pnx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_51597677 0.76 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr25_+_29160102 0.73 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr2_+_55982300 0.69 ENSDART00000183903
nmrk2
nicotinamide riboside kinase 2
chr23_+_20110086 0.68 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr13_+_22479988 0.65 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr6_-_54815886 0.63 ENSDART00000180793
ENSDART00000007498
tnni1b
troponin I type 1b (skeletal, slow)
chr20_+_26966725 0.62 ENSDART00000029781
ahsa1a
AHA1, activator of heat shock protein ATPase homolog 1a
chr7_-_71758307 0.59 ENSDART00000161067
ENSDART00000165253
myom1b
myomesin 1b
chr25_+_35019693 0.57 ENSDART00000046218
flnca
filamin C, gamma a (actin binding protein 280)
chr12_-_33357655 0.55 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr19_-_25119443 0.53 ENSDART00000148953
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr25_+_5035343 0.50 ENSDART00000011751
parvb
parvin, beta
chr20_-_37813863 0.48 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr22_+_16308450 0.47 ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr20_-_9462433 0.47 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr9_-_813511 0.44 ENSDART00000082368
marco
macrophage receptor with collagenous structure
chr6_+_6924637 0.40 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr6_-_40581376 0.40 ENSDART00000185412
tspo
translocator protein
chr12_+_22580579 0.40 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr19_+_2631565 0.40 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr1_-_14332283 0.39 ENSDART00000090025
wfs1a
Wolfram syndrome 1a (wolframin)
chr11_+_44135351 0.38 ENSDART00000182914
FO704721.1

chr11_-_2131280 0.36 ENSDART00000008409
calcoco1b
calcium binding and coiled-coil domain 1b
chr4_+_9011448 0.36 ENSDART00000192357
samm50l
sorting and assembly machinery component 50 homolog, like
chr16_-_42933332 0.35 ENSDART00000057305
thbs3a
thrombospondin 3a
chr17_-_37395460 0.34 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr2_-_2957970 0.33 ENSDART00000162505
si:ch1073-82l19.1
si:ch1073-82l19.1
chr4_+_76575585 0.33 ENSDART00000131588
ms4a17a.11
membrane-spanning 4-domains, subfamily A, member 17A.11
chr11_-_13107106 0.33 ENSDART00000184477
elovl1b
ELOVL fatty acid elongase 1b
chr9_+_43799829 0.33 ENSDART00000186240
ube2e3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr15_-_36533322 0.33 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
si:dkey-262k9.4
chr19_-_2861444 0.32 ENSDART00000169053
clec3bb
C-type lectin domain family 3, member Bb
chr23_-_31512496 0.32 ENSDART00000158755
ENSDART00000143425
eya4
EYA transcriptional coactivator and phosphatase 4
chr15_+_31701716 0.31 ENSDART00000113370
b3glcta
beta 3-glucosyltransferase a
chr12_-_33354409 0.31 ENSDART00000178515
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr5_+_40485503 0.31 ENSDART00000051055
ndufs4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr4_+_22480169 0.30 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr25_+_31267268 0.30 ENSDART00000181239
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr3_+_59784632 0.30 ENSDART00000084729
pecam1
platelet/endothelial cell adhesion molecule 1
chr8_+_52619365 0.29 ENSDART00000162953
cyr61l2
cysteine-rich, angiogenic inducer, 61 like 2
chr3_-_15734358 0.28 ENSDART00000137325
mvp
major vault protein
chr3_-_15734530 0.27 ENSDART00000141142
mvp
major vault protein
chr1_-_51719110 0.27 ENSDART00000190574
rnaseh2a
ribonuclease H2, subunit A
chr16_-_31754102 0.27 ENSDART00000185043
ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr6_-_19271210 0.26 ENSDART00000163628
ENSDART00000159124
zgc:174863
zgc:174863
chr25_+_28825657 0.26 ENSDART00000153625
nfybb
nuclear transcription factor Y, beta b
chr1_+_7517454 0.26 ENSDART00000016139
lancl1
LanC antibiotic synthetase component C-like 1 (bacterial)
chr24_-_6078222 0.26 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr15_-_4528326 0.25 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr24_+_22485710 0.25 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr20_-_29864390 0.25 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr25_+_31277415 0.24 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr25_-_13490744 0.23 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr8_-_52562672 0.23 ENSDART00000159333
ENSDART00000159974
si:ch73-199g24.2
si:ch73-199g24.2
chr17_+_12865746 0.23 ENSDART00000157083
ralgapa1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr24_+_3307857 0.23 ENSDART00000106527
gyg1b
glycogenin 1b
chr6_-_40778294 0.23 ENSDART00000019845
arpc4
actin related protein 2/3 complex, subunit 4
chr10_+_32104305 0.22 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr15_-_9272328 0.22 ENSDART00000172114
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr4_+_77943184 0.22 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr18_+_48423973 0.22 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr13_-_35808904 0.22 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr14_+_924876 0.22 ENSDART00000183908
myoz3a
myozenin 3a
chr14_-_4145594 0.21 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr17_+_21902058 0.21 ENSDART00000142178
plekha1a
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a
chr5_+_19343880 0.21 ENSDART00000148130
acacb
acetyl-CoA carboxylase beta
chr16_-_51271962 0.20 ENSDART00000164021
ENSDART00000046420
serpinb1l1
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr9_-_22834860 0.20 ENSDART00000146486
neb
nebulin
chr12_+_20352400 0.20 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr3_+_17933132 0.20 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr9_-_14683574 0.20 ENSDART00000144022
pard3bb
par-3 family cell polarity regulator beta b
chr5_-_30074332 0.19 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr19_-_5669122 0.19 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr19_-_38611814 0.19 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr18_-_46258612 0.19 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
chr1_-_58963395 0.19 ENSDART00000130415
CABZ01115881.1

chr24_+_37640626 0.18 ENSDART00000008047
wdr24
WD repeat domain 24
chr13_+_35339182 0.18 ENSDART00000019323
jag1b
jagged 1b
chr23_-_43453975 0.18 ENSDART00000134142
rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr4_+_11458078 0.18 ENSDART00000037600
ankrd16
ankyrin repeat domain 16
chr16_-_41488023 0.17 ENSDART00000169312
cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr12_+_30265802 0.17 ENSDART00000182412
afap1l2
actin filament associated protein 1-like 2
chr13_-_36798204 0.17 ENSDART00000012357
sav1
salvador family WW domain containing protein 1
chr6_-_30954268 0.17 ENSDART00000154523
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr8_-_21372446 0.16 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr4_-_277081 0.16 ENSDART00000166174
si:ch73-252i11.1
si:ch73-252i11.1
chr21_+_25198637 0.16 ENSDART00000164972
si:dkey-183i3.6
si:dkey-183i3.6
chr24_-_41320037 0.16 ENSDART00000129058
rheb
Ras homolog, mTORC1 binding
chr3_+_27798094 0.16 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr6_+_50381347 0.16 ENSDART00000055504
cyc1
cytochrome c-1
chr2_-_37140423 0.16 ENSDART00000144220
tspan37
tetraspanin 37
chr10_-_42297889 0.16 ENSDART00000099262
tcf7l1a
transcription factor 7 like 1a
chr23_+_4741543 0.16 ENSDART00000144761
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
chr25_+_31276842 0.15 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr23_+_19813677 0.15 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr20_+_26880668 0.15 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr16_-_51288178 0.15 ENSDART00000079864
zgc:173729
zgc:173729
chr13_+_35637048 0.15 ENSDART00000085037
thbs2a
thrombospondin 2a
chr23_-_1348933 0.15 ENSDART00000168981
CABZ01078120.1

chr5_+_69747417 0.15 ENSDART00000153717
si:ch211-275j6.5
si:ch211-275j6.5
chr19_-_19379084 0.15 ENSDART00000165206
smarcc1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr3_-_58798377 0.15 ENSDART00000161248
si:ch73-281f12.4
si:ch73-281f12.4
chr7_-_51368681 0.15 ENSDART00000146385
arhgap36
Rho GTPase activating protein 36
chr21_+_43328685 0.15 ENSDART00000109620
ENSDART00000139668
sept8a
septin 8a
chr9_-_3934963 0.14 ENSDART00000062336
ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr13_+_35637875 0.14 ENSDART00000180657
thbs2a
thrombospondin 2a
chr3_-_15210491 0.14 ENSDART00000037906
hirip3
HIRA interacting protein 3
chr1_+_513986 0.14 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr3_-_34084387 0.14 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr14_+_30795559 0.14 ENSDART00000006132
cfl1
cofilin 1
chr24_+_19415124 0.14 ENSDART00000186931
sulf1
sulfatase 1
chr20_+_535458 0.13 ENSDART00000152453
dse
dermatan sulfate epimerase
chr7_-_30174882 0.13 ENSDART00000110409
frmd5
FERM domain containing 5
chr11_+_43043171 0.13 ENSDART00000180344
CABZ01092982.1

chr16_-_7828838 0.13 ENSDART00000191434
ENSDART00000108653
tcaim
T cell activation inhibitor, mitochondrial
chr12_+_3571770 0.13 ENSDART00000164707
ENSDART00000189819
coa3a
cytochrome C oxidase assembly factor 3a
chr16_+_41826584 0.13 ENSDART00000147523
si:dkey-199f5.6
si:dkey-199f5.6
chr23_-_16485190 0.13 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr12_-_28363111 0.13 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr9_-_950004 0.13 ENSDART00000168917
SCTR
secretin receptor
chr16_+_13818743 0.13 ENSDART00000090191
flcn
folliculin
chr22_-_26274177 0.13 ENSDART00000060978
wdr83
WD repeat domain containing 83
chr18_+_17827149 0.13 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr3_+_32832538 0.13 ENSDART00000139410
cd2bp2
CD2 (cytoplasmic tail) binding protein 2
chr6_-_55399214 0.13 ENSDART00000168367
ctsa
cathepsin A
chr9_+_38372216 0.13 ENSDART00000141895
plcd4b
phospholipase C, delta 4b
chr13_+_22295905 0.13 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr9_-_5263947 0.12 ENSDART00000088342
cytip
cytohesin 1 interacting protein
chr14_-_7137808 0.12 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr6_+_24420523 0.12 ENSDART00000185461
tgfbr3
transforming growth factor, beta receptor III
chr24_-_8777781 0.12 ENSDART00000082362
ENSDART00000177400
mak
male germ cell-associated kinase
chr18_-_2727764 0.12 ENSDART00000160841
ARHGEF17
si:ch211-248g20.5
chr17_+_44697604 0.12 ENSDART00000156625
pgfb
placental growth factor b
chr21_-_20939488 0.12 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr15_+_5088210 0.12 ENSDART00000183423
mxf
myxovirus (influenza virus) resistance F
chr6_-_33878665 0.12 ENSDART00000129916
tmem69
transmembrane protein 69
chr19_-_3724605 0.12 ENSDART00000123757
smim13
small integral membrane protein 13
chr16_-_26855936 0.11 ENSDART00000167320
ENSDART00000078119
ino80c
INO80 complex subunit C
chr13_-_42400647 0.11 ENSDART00000043069
march5
membrane-associated ring finger (C3HC4) 5
chr17_+_24722646 0.11 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr2_-_26720854 0.11 ENSDART00000148110
si:dkey-181m9.8
si:dkey-181m9.8
chr18_-_21950751 0.11 ENSDART00000043452
tsnaxip1
translin-associated factor X interacting protein 1
chr20_-_14925281 0.11 ENSDART00000152641
dnm3a
dynamin 3a
chr2_+_30369116 0.11 ENSDART00000142137
pi15b
peptidase inhibitor 15b
chr24_+_11908833 0.11 ENSDART00000178622
fen1
flap structure-specific endonuclease 1
chr11_+_2506516 0.11 ENSDART00000130886
ENSDART00000189767
NABP2
si:ch73-190f16.2
chr12_+_26877381 0.11 ENSDART00000087329
znf438
zinc finger protein 438
chr9_+_30421489 0.11 ENSDART00000145025
ENSDART00000132058
zgc:113314
zgc:113314
chr23_+_29885019 0.11 ENSDART00000167059
aurkaip1
aurora kinase A interacting protein 1
chr13_+_15190677 0.11 ENSDART00000142240
ENSDART00000129045
mavs
mitochondrial antiviral signaling protein
chr24_+_40905100 0.10 ENSDART00000167854
scn12ab
sodium channel, voltage gated, type XII, alpha b
chr11_+_33818179 0.10 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr19_+_3826782 0.10 ENSDART00000169222
oscp1a
organic solute carrier partner 1a
chr6_+_9677420 0.10 ENSDART00000064995
sumo1
small ubiquitin-like modifier 1
chr20_-_1378514 0.10 ENSDART00000181830
scara5
scavenger receptor class A, member 5 (putative)
chr23_+_44374041 0.10 ENSDART00000136056
ephb4b
eph receptor B4b
chr22_+_2254972 0.10 ENSDART00000144906
znf1157
zinc finger protein 1157
chr20_+_46513651 0.10 ENSDART00000152977
zc3h14
zinc finger CCCH-type containing 14
chr9_-_6372535 0.10 ENSDART00000149189
ecrg4a
esophageal cancer related gene 4a
chr1_-_23268569 0.10 ENSDART00000143948
rfc1
replication factor C (activator 1) 1
chr24_-_36680261 0.10 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr18_-_46256560 0.10 ENSDART00000171375
si:dkey-244a7.1
si:dkey-244a7.1
chr18_-_43884044 0.09 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr24_+_22731228 0.09 ENSDART00000146733
si:dkey-225k4.1
si:dkey-225k4.1
chr20_+_53181017 0.09 ENSDART00000189692
ENSDART00000177109
FIG4
FIG4 phosphoinositide 5-phosphatase
chr15_+_934660 0.09 ENSDART00000154248
si:dkey-77f5.10
si:dkey-77f5.10
chr21_+_45757317 0.09 ENSDART00000163152
h2afy
H2A histone family, member Y
chr22_-_7702958 0.09 ENSDART00000193046
si:ch211-59h6.1
si:ch211-59h6.1
chr20_-_9095105 0.09 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr15_-_35252522 0.09 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr6_+_3280939 0.09 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr8_-_31107537 0.09 ENSDART00000098925
vgll4l
vestigial like 4 like
chr7_-_24046999 0.09 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr19_-_44064842 0.09 ENSDART00000151541
mterf3
mitochondrial transcription termination factor 3
chr8_+_20140321 0.09 ENSDART00000012120
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr24_+_11908480 0.09 ENSDART00000024224
fen1
flap structure-specific endonuclease 1
chr14_+_23717165 0.09 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr11_-_44979281 0.09 ENSDART00000190972
ldb1b
LIM-domain binding 1b
chr15_+_47492838 0.09 ENSDART00000122372
sik3
SIK family kinase 3
chr4_-_3353595 0.08 ENSDART00000009076
pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr11_+_25129013 0.08 ENSDART00000132879
ndrg3a
ndrg family member 3a
chr25_-_36827491 0.08 ENSDART00000170941
CU929365.1

chr22_-_30770751 0.08 ENSDART00000172115
AL831726.2

chr20_-_14924858 0.08 ENSDART00000047039
dnm3a
dynamin 3a
chr5_-_38063585 0.08 ENSDART00000164947
si:dkey-111e8.5
si:dkey-111e8.5
chr5_-_52010122 0.08 ENSDART00000073627
ENSDART00000163898
ENSDART00000051003
cdk7
cyclin-dependent kinase 7
chr20_+_25225112 0.08 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
moxd1
monooxygenase, DBH-like 1
chr11_+_11303458 0.08 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
si:dkey-23f9.4
chr15_-_2493771 0.08 ENSDART00000184906
neu4
sialidase 4
chr12_+_5977777 0.08 ENSDART00000152302
si:ch211-131k2.2
si:ch211-131k2.2
chr3_+_29445473 0.07 ENSDART00000020381
grap2a
GRB2-related adaptor protein 2a
chr8_-_49908978 0.07 ENSDART00000172642
agtpbp1
ATP/GTP binding protein 1
chr4_-_45100253 0.07 ENSDART00000163870
si:dkey-51d8.3
si:dkey-51d8.3
chr7_+_8456999 0.07 ENSDART00000172880
jac4
jacalin 4
chr10_+_28160265 0.07 ENSDART00000022484
rnft1
ring finger protein, transmembrane 1
chr16_+_54209504 0.07 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr2_+_30368800 0.07 ENSDART00000179564
pi15b
peptidase inhibitor 15b
chr1_-_57629639 0.07 ENSDART00000158984
zmp:0000001289
zmp:0000001289
chr19_-_31402429 0.07 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr21_-_26490186 0.07 ENSDART00000009889
zgc:110540
zgc:110540

Network of associatons between targets according to the STRING database.

First level regulatory network of gsx2+pnx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.3 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.4 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.1 0.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.8 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.2 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 0.6 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 2.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.5 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.3 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.7 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755) protein homotrimerization(GO:0070207)
0.0 0.1 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.0 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.1 GO:0031430 M band(GO:0031430)
0.0 2.0 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.6 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.7 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.8 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.6 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport