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PRJNA207719: Tissue specific transcriptome profiling

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Results for hlx1

Z-value: 0.43

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Transcription factors associated with hlx1

Gene Symbol Gene ID Gene Info
hlx1
ENSDARG00000009134 H2.0-like homeo box 1 (Drosophila)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hlx1dr11_v1_chr20_-_52199296_52199311-0.138.4e-01Click!

Activity profile of hlx1 motif

Sorted Z-values of hlx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_22918214 0.46 ENSDART00000163908
rnasekb
ribonuclease, RNase K b
chr3_+_29714775 0.41 ENSDART00000041388
cacng2a
calcium channel, voltage-dependent, gamma subunit 2a
chr17_-_29119362 0.38 ENSDART00000104204
foxg1a
forkhead box G1a
chr5_-_66702479 0.36 ENSDART00000129197
mn1b
meningioma 1b
chr3_-_48716422 0.29 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr8_-_39952727 0.28 ENSDART00000181310
cabp1a
calcium binding protein 1a
chr3_-_20040636 0.28 ENSDART00000104118
atxn7l3
ataxin 7-like 3
chr2_+_47623202 0.27 ENSDART00000154465
si:ch211-165b10.3
si:ch211-165b10.3
chr10_+_26926654 0.26 ENSDART00000078980
ENSDART00000100289
rab1bb
RAB1B, member RAS oncogene family b
chr1_+_6172786 0.20 ENSDART00000126468
prkag3a
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr17_+_9310259 0.19 ENSDART00000186158
ENSDART00000190329
NPAS3
neuronal PAS domain protein 3
chr2_+_2223837 0.16 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr24_-_21404367 0.16 ENSDART00000152093
atp8a2
ATPase phospholipid transporting 8A2
chr8_+_50953776 0.16 ENSDART00000013870
zgc:56596
zgc:56596
chr6_+_51773873 0.13 ENSDART00000156516
tmem74b
transmembrane protein 74B
chr12_-_2522487 0.11 ENSDART00000022471
ENSDART00000145213
mapk8b
mitogen-activated protein kinase 8b
chr10_+_43039947 0.11 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr22_-_20950448 0.11 ENSDART00000002029
fkbp8
FK506 binding protein 8
chr9_+_45227028 0.10 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr16_+_7380463 0.09 ENSDART00000029727
ENSDART00000149086
atg5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr1_-_26294995 0.09 ENSDART00000168594
cxxc4
CXXC finger 4
chr9_-_23118350 0.08 ENSDART00000020884
lypd6
LY6/PLAUR domain containing 6
chr1_-_19502322 0.07 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr2_-_9818640 0.07 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
ap2m1b
adaptor-related protein complex 2, mu 1 subunit, b
chr4_-_22338906 0.07 ENSDART00000131402
golgb1
golgin B1
chr8_+_7801060 0.07 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr13_+_22964868 0.02 ENSDART00000142129
tacr2
tachykinin receptor 2
chr8_-_11834599 0.02 ENSDART00000190986
rapgef1a
Rap guanine nucleotide exchange factor (GEF) 1a
chr17_+_7620220 0.01 ENSDART00000081447
fbxo30a
F-box protein 30a

Network of associatons between targets according to the STRING database.

First level regulatory network of hlx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.4 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.4 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)