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PRJNA207719: Tissue specific transcriptome profiling

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Results for hmbox1a+zgc:91944

Z-value: 1.19

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Transcription factors associated with hmbox1a+zgc:91944

Gene Symbol Gene ID Gene Info
hmbox1a
ENSDARG00000027082 homeobox containing 1a
zgc
ENSDARG00000035887 91944
hmbox1a
ENSDARG00000109287 homeobox containing 1 b
zgc
ENSDARG00000114642 91944

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CABZ01078261.1dr11_v1_chr20_+_49787584_49787584-0.913.3e-02Click!
hmbox1adr11_v1_chr17_-_16324565_16324565-0.721.7e-01Click!
zgc:91944dr11_v1_chr19_-_32600638_32600638-0.523.7e-01Click!

Activity profile of hmbox1a+zgc:91944 motif

Sorted Z-values of hmbox1a+zgc:91944 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_21222287 1.65 ENSDART00000159905
si:ch211-175m2.4
si:ch211-175m2.4
chr7_-_71758307 1.49 ENSDART00000161067
ENSDART00000165253
myom1b
myomesin 1b
chr15_-_17074393 1.24 ENSDART00000155526
si:ch211-24o10.6
si:ch211-24o10.6
chr7_+_35075847 0.98 ENSDART00000193469
ENSDART00000037346
ctrb1
chymotrypsinogen B1
chr2_+_55982300 0.92 ENSDART00000183903
nmrk2
nicotinamide riboside kinase 2
chr2_-_42128714 0.90 ENSDART00000047055
trim55a
tripartite motif containing 55a
chr13_-_37620091 0.86 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
zgc:152791
chr7_+_31891110 0.81 ENSDART00000173883
mybpc3
myosin binding protein C, cardiac
chr25_+_13205878 0.79 ENSDART00000162319
ENSDART00000162283
si:ch211-147m6.2
si:ch211-147m6.2
chr5_-_42083363 0.77 ENSDART00000162596
cxcl11.5
chemokine (C-X-C motif) ligand 11, duplicate 5
chr4_+_72798545 0.71 ENSDART00000181727
MYRFL
myelin regulatory factor-like
chr13_+_8840772 0.71 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr20_+_53577502 0.69 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr19_-_40192249 0.68 ENSDART00000051972
grn1
granulin 1
chr14_+_11458044 0.67 ENSDART00000186425
si:ch211-153b23.5
si:ch211-153b23.5
chr2_-_21438492 0.63 ENSDART00000046098
plcd1b
phospholipase C, delta 1b
chr7_-_71758613 0.63 ENSDART00000166724
myom1b
myomesin 1b
chr18_-_20458840 0.61 ENSDART00000177125
kif23
kinesin family member 23
chr17_+_33375469 0.61 ENSDART00000032827
zgc:162964
zgc:162964
chr17_-_25382367 0.60 ENSDART00000162306
ENSDART00000165282
lck
LCK proto-oncogene, Src family tyrosine kinase
chr15_+_6459847 0.60 ENSDART00000157250
ENSDART00000065824
bace2
beta-site APP-cleaving enzyme 2
chr18_-_46258612 0.59 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
chr21_-_32036597 0.58 ENSDART00000114964
zgc:165573
zgc:165573
chr9_-_98982 0.57 ENSDART00000147882
lims2
LIM and senescent cell antigen-like domains 2
chr20_-_30377221 0.56 ENSDART00000126229
rps7
ribosomal protein S7
chr3_-_31254379 0.56 ENSDART00000189376
apnl
actinoporin-like protein
chr24_-_11076400 0.56 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr17_+_5985933 0.55 ENSDART00000190844
zgc:194275
zgc:194275
chr4_+_20566371 0.54 ENSDART00000127576
BX248410.1

chr22_-_23000815 0.53 ENSDART00000137111
ptprc
protein tyrosine phosphatase, receptor type, C
chr3_-_34054081 0.49 ENSDART00000151590
ighv1-2
immunoglobulin heavy variable 1-2
chr9_+_48088031 0.49 ENSDART00000073870
si:ch73-54b5.2
si:ch73-54b5.2
chr10_+_38610741 0.49 ENSDART00000126444
mmp13a
matrix metallopeptidase 13a
chr3_-_44059902 0.48 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr1_-_513762 0.48 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr21_+_33459524 0.48 ENSDART00000053205
cd74b
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr5_-_61624693 0.48 ENSDART00000141323
si:dkey-261j4.4
si:dkey-261j4.4
chr18_-_46354269 0.48 ENSDART00000010813
foxa3
forkhead box A3
chr3_-_36708503 0.47 ENSDART00000166896
myh11b
myosin, heavy chain 11b, smooth muscle
chr14_-_29858883 0.46 ENSDART00000141034
sorbs2b
sorbin and SH3 domain containing 2b
chr2_+_55984788 0.46 ENSDART00000183599
nmrk2
nicotinamide riboside kinase 2
chr12_-_26538823 0.45 ENSDART00000143213
acsf2
acyl-CoA synthetase family member 2
chr2_-_2957970 0.45 ENSDART00000162505
si:ch1073-82l19.1
si:ch1073-82l19.1
chr16_-_42004544 0.44 ENSDART00000034544
caspa
caspase a
chr16_+_24842662 0.44 ENSDART00000157333
si:dkey-79d12.6
si:dkey-79d12.6
chr22_+_19218733 0.43 ENSDART00000183212
ENSDART00000133595
si:dkey-21e2.7
si:dkey-21e2.7
chr15_-_23814330 0.43 ENSDART00000153843
si:ch211-167j9.5
si:ch211-167j9.5
chr14_+_48862987 0.43 ENSDART00000167810
zgc:154054
zgc:154054
chr4_+_76705830 0.42 ENSDART00000064312
ms4a17a.7
membrane-spanning 4-domains, subfamily A, member 17A.7
chr7_-_16195144 0.42 ENSDART00000173492
btr04
bloodthirsty-related gene family, member 4
chr8_-_47152001 0.42 ENSDART00000163922
ENSDART00000110512
ENSDART00000024320
ybx1
Y box binding protein 1
chr11_-_40504170 0.41 ENSDART00000165394
si:dkeyp-61b2.1
si:dkeyp-61b2.1
chr7_-_25133783 0.41 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
badb
BCL2 associated agonist of cell death b
chr20_+_46371458 0.41 ENSDART00000152912
adgrg11
adhesion G protein-coupled receptor G11
chr3_+_49043917 0.41 ENSDART00000158212
zgc:92161
zgc:92161
chr8_+_47100863 0.41 ENSDART00000114811
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr1_+_44395976 0.41 ENSDART00000159686
ENSDART00000189905
ENSDART00000025145
unc93b1
unc-93 homolog B1, TLR signaling regulator
chr6_-_40581376 0.41 ENSDART00000185412
tspo
translocator protein
chr19_-_3781405 0.41 ENSDART00000170609
btr19
bloodthirsty-related gene family, member 19
chr15_-_39971756 0.40 ENSDART00000063789
rps5
ribosomal protein S5
chr16_-_17699111 0.40 ENSDART00000108581
si:dkey-17m8.1
si:dkey-17m8.1
chr25_-_13188214 0.40 ENSDART00000187298
si:ch211-147m6.1
si:ch211-147m6.1
chr3_+_39540014 0.39 ENSDART00000074848
zgc:165423
zgc:165423
chr8_+_44759576 0.39 ENSDART00000132115
si:ch1073-459j12.1
si:ch1073-459j12.1
chr13_-_21672131 0.39 ENSDART00000067537
elovl6l
ELOVL family member 6, elongation of long chain fatty acids like
chr23_-_11130683 0.39 ENSDART00000181189
cntn3a.2
contactin 3a, tandem duplicate 2
chr21_-_22730832 0.39 ENSDART00000101797
fbxo40.1
F-box protein 40, tandem duplicate 1
chr21_-_45920 0.38 ENSDART00000040422
bhmt
betaine-homocysteine methyltransferase
chr24_-_12958668 0.38 ENSDART00000178982
FITM1 (1 of many)
Danio rerio fat storage inducing transmembrane protein 1 (LOC792443), mRNA.
chr5_-_42904329 0.38 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr3_+_22335030 0.38 ENSDART00000055676
zgc:103564
zgc:103564
chr22_+_19366866 0.37 ENSDART00000137301
si:dkey-21e2.12
si:dkey-21e2.12
chr16_+_31921812 0.37 ENSDART00000176928
ENSDART00000193733
rps9
ribosomal protein S9
chr19_+_31585917 0.37 ENSDART00000132182
gmnn
geminin, DNA replication inhibitor
chr24_-_4782052 0.37 ENSDART00000149911
agtr1b
angiotensin II receptor, type 1b
chr19_+_31585341 0.37 ENSDART00000052185
gmnn
geminin, DNA replication inhibitor
chr19_+_823945 0.36 ENSDART00000142287
ppp1r18
protein phosphatase 1, regulatory subunit 18
chr7_+_69841017 0.36 ENSDART00000169107
FO818704.1

chr11_-_1400507 0.36 ENSDART00000173029
ENSDART00000172953
ENSDART00000111140
rpl29
ribosomal protein L29
chr6_-_40657653 0.35 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr3_-_2033105 0.35 ENSDART00000135249
si:dkey-88j15.3
si:dkey-88j15.3
chr16_+_32152612 0.35 ENSDART00000008880
gprc6a
G protein-coupled receptor, class C, group 6, member A
chr3_+_30922947 0.35 ENSDART00000184060
cldni
claudin i
chr10_+_29259882 0.34 ENSDART00000180606
sytl2a
synaptotagmin-like 2a
chr16_-_31754102 0.34 ENSDART00000185043
ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr7_-_16194952 0.34 ENSDART00000173739
btr04
bloodthirsty-related gene family, member 4
chr11_+_42474694 0.34 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
si:ch1073-165f9.2
chr22_-_1079773 0.34 ENSDART00000136668
si:ch1073-15f12.3
si:ch1073-15f12.3
chr19_-_5669122 0.34 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr14_-_29859067 0.33 ENSDART00000136380
sorbs2b
sorbin and SH3 domain containing 2b
chr3_-_23512285 0.33 ENSDART00000159151
BX682558.1

chr21_+_5560040 0.33 ENSDART00000163205
si:ch211-134a4.6
si:ch211-134a4.6
chr10_-_22095505 0.33 ENSDART00000140210
ponzr10
plac8 onzin related protein 10
chr20_-_33512275 0.32 ENSDART00000185959
paplnb
papilin b, proteoglycan-like sulfated glycoprotein
chr8_+_39724138 0.32 ENSDART00000009323
pla2g1b
phospholipase A2, group IB (pancreas)
chr7_+_25049545 0.32 ENSDART00000173896
ENSDART00000173566
si:dkey-23i12.7
ppp2r5b
si:dkey-23i12.7
protein phosphatase 2, regulatory subunit B', beta
chr7_+_41295974 0.32 ENSDART00000173568
ENSDART00000173544
si:dkey-86l18.10
si:dkey-86l18.10
chr22_-_23590069 0.32 ENSDART00000172067
f13b
coagulation factor XIII, B polypeptide
chr2_+_2470687 0.31 ENSDART00000184024
ENSDART00000061955
myl13
myosin, light chain 13
chr12_+_10631266 0.31 ENSDART00000161455
csf3a
colony stimulating factor 3 (granulocyte) a
chr7_-_2430286 0.31 ENSDART00000129312
zgc:66473
zgc:66473
chr19_+_45962016 0.31 ENSDART00000169710
utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr16_+_16529748 0.31 ENSDART00000029579
ccdc12
coiled-coil domain containing 12
chr10_+_439692 0.30 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr5_+_8246603 0.30 ENSDART00000167373
si:ch1073-475a24.1
si:ch1073-475a24.1
chr21_+_5635420 0.30 ENSDART00000168158
shroom3
shroom family member 3
chr5_-_11809404 0.30 ENSDART00000132564
nf2a
neurofibromin 2a (merlin)
chr20_+_15015557 0.30 ENSDART00000039345
myoc
myocilin
chr23_-_44786844 0.29 ENSDART00000148669
si:ch73-269m23.5
si:ch73-269m23.5
chr21_-_26558268 0.29 ENSDART00000065390
CR631122.1

chr12_+_3723650 0.29 ENSDART00000179922
ENSDART00000152482
ENSDART00000108771
pagr1
PAXIP1 associated glutamate-rich protein 1
chr17_-_15188440 0.29 ENSDART00000151885
wdhd1
WD repeat and HMG-box DNA binding protein 1
chr20_+_53522059 0.28 ENSDART00000147570
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr5_-_30074332 0.28 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr18_-_21170264 0.28 ENSDART00000175265
BX571884.1

chr9_+_20519846 0.28 ENSDART00000109680
ENSDART00000142220
vtcn1
V-set domain containing T cell activation inhibitor 1
chr7_-_69121896 0.28 ENSDART00000130227
crispld2
cysteine-rich secretory protein LCCL domain containing 2
chr8_-_51578926 0.27 ENSDART00000190625
ankrd39
ankyrin repeat domain 39
chr14_+_23709134 0.27 ENSDART00000191162
ENSDART00000179754
ENSDART00000054266
gnpda1
glucosamine-6-phosphate deaminase 1
chr21_-_22474362 0.27 ENSDART00000169659
myo5b
myosin VB
chr25_-_12923482 0.27 ENSDART00000161754
CR450808.1

chr23_+_41679586 0.27 ENSDART00000067662
CU914487.1

chr7_+_53199763 0.26 ENSDART00000160097
cdh28
cadherin 28
chr4_-_45100253 0.26 ENSDART00000163870
si:dkey-51d8.3
si:dkey-51d8.3
chr17_+_30591287 0.26 ENSDART00000154243
si:dkey-190l8.2
si:dkey-190l8.2
chr7_-_2292403 0.26 ENSDART00000075856
zgc:66473
zgc:66473
chr7_+_17443567 0.26 ENSDART00000060383
nitr2b
novel immune-type receptor 2b
chr1_-_7939514 0.26 ENSDART00000139774
si:dkey-79f11.9
si:dkey-79f11.9
chr10_-_26196383 0.26 ENSDART00000192925
fhdc3
FH2 domain containing 3
chr6_+_4160579 0.26 ENSDART00000105278
ENSDART00000187932
ENSDART00000111817
trim25l
tripartite motif containing 25, like
chr17_-_47142249 0.25 ENSDART00000184705
CU915775.1

chr8_+_30699429 0.25 ENSDART00000005345
upb1
ureidopropionase, beta
chr17_+_6563307 0.25 ENSDART00000156454
adgrf3a
adhesion G protein-coupled receptor F3a
chr8_+_30664077 0.25 ENSDART00000138750
adora2aa
adenosine A2a receptor a
chr13_-_18548729 0.25 ENSDART00000187686
BX908770.1

chr19_+_9295244 0.25 ENSDART00000132255
ENSDART00000144299
si:ch73-15n24.1
si:ch73-15n24.1
chr24_-_29868151 0.25 ENSDART00000184802
aglb
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr23_-_23160088 0.25 ENSDART00000141853
noc2l
NOC2-like nucleolar associated transcriptional repressor
chr2_-_24061575 0.25 ENSDART00000089234
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr3_-_18675688 0.25 ENSDART00000048218
slc5a11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr8_+_23439340 0.25 ENSDART00000109932
ENSDART00000185469
foxp3b
forkhead box P3b
chr22_-_23706771 0.25 ENSDART00000159771
cfhl1
complement factor H like 1
chr18_+_5454341 0.24 ENSDART00000192649
dtwd1
DTW domain containing 1
chr25_+_25085526 0.24 ENSDART00000171627
si:ch73-182e20.4
si:ch73-182e20.4
chr23_+_24085531 0.24 ENSDART00000139710
ttll10
tubulin tyrosine ligase-like family, member 10
chr7_+_73807504 0.24 ENSDART00000166244
si:ch73-252p3.1
si:ch73-252p3.1
chr2_+_49713592 0.23 ENSDART00000189624
BX323861.3

chr10_-_26202766 0.23 ENSDART00000136393
fhdc3
FH2 domain containing 3
chr2_+_11029138 0.23 ENSDART00000138737
ENSDART00000081058
ENSDART00000153662
acot11a
acyl-CoA thioesterase 11a
chr1_-_29061285 0.23 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gemin8
gem (nuclear organelle) associated protein 8
chr4_+_71989418 0.23 ENSDART00000170996
parp11
poly(ADP-ribose) polymerase family member 11
chr20_-_1378514 0.23 ENSDART00000181830
scara5
scavenger receptor class A, member 5 (putative)
chr15_-_34892664 0.23 ENSDART00000153787
ENSDART00000099721
rnf183
ring finger protein 183
chr5_-_13564961 0.23 ENSDART00000146827
si:ch211-230g14.3
si:ch211-230g14.3
chr1_-_58505626 0.23 ENSDART00000171304
si:ch73-236c18.8
si:ch73-236c18.8
chr4_+_74929427 0.22 ENSDART00000174082
nup50
nucleoporin 50
chr11_+_2089461 0.22 ENSDART00000172865
rargb
retinoic acid receptor, gamma b
chr16_+_40560622 0.22 ENSDART00000038294
tp53inp1
tumor protein p53 inducible nuclear protein 1
chr24_-_9979342 0.22 ENSDART00000138576
ENSDART00000191206
zgc:171977
zgc:171977
chr19_+_7595924 0.22 ENSDART00000140083
s100s
S100 calcium binding protein S
chr9_-_34986827 0.22 ENSDART00000137862
si:ch211-160b11.4
si:ch211-160b11.4
chr10_-_44008241 0.22 ENSDART00000137686
acads
acyl-CoA dehydrogenase short chain
chr25_+_25085349 0.22 ENSDART00000192166
si:ch73-182e20.4
si:ch73-182e20.4
chr19_-_33370271 0.22 ENSDART00000132628
nkd3l
naked cuticle homolog 3, like
chr2_+_33926606 0.22 ENSDART00000111430
kif2c
kinesin family member 2C
chr7_+_2849020 0.22 ENSDART00000168695
BX004857.1

chr19_+_31044487 0.21 ENSDART00000143494
ankmy2b
ankyrin repeat and MYND domain containing 2b
chr1_-_11104805 0.21 ENSDART00000147648
knl1
kinetochore scaffold 1
chr23_-_32404022 0.21 ENSDART00000156387
ENSDART00000155508
si:ch211-66i15.4
si:ch211-66i15.4
chr21_+_40287100 0.21 ENSDART00000032154
or115-5
odorant receptor, family F, subfamily 115, member 5
chr12_+_34896956 0.20 ENSDART00000055415
prph2a
peripherin 2a (retinal degeneration, slow)
chr18_+_33132266 0.20 ENSDART00000151623
si:ch211-229c8.14
si:ch211-229c8.14
chr5_-_26834511 0.20 ENSDART00000136713
ENSDART00000192932
ENSDART00000113246
si:ch211-102c2.4
si:ch211-102c2.4
chr2_-_57264262 0.20 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
mbd3a
methyl-CpG binding domain protein 3a
chr13_+_8693410 0.20 ENSDART00000138448
ttc7a
tetratricopeptide repeat domain 7A
chr12_+_10706772 0.20 ENSDART00000158227
top2a
DNA topoisomerase II alpha
chr16_+_11834516 0.20 ENSDART00000146611
cxcr3.3
chemokine (C-X-C motif) receptor 3, tandem duplicate 3
chr21_+_23108420 0.20 ENSDART00000192394
ENSDART00000088459
htr3b
5-hydroxytryptamine (serotonin) receptor 3B
chr13_+_40635844 0.20 ENSDART00000137310
hpse2
heparanase 2
chr1_+_10051763 0.19 ENSDART00000011701
fgb
fibrinogen beta chain
chr13_+_9548849 0.19 ENSDART00000122695
pomk
protein-O-mannose kinase
chr5_-_67799617 0.19 ENSDART00000192117
eif4e1b
eukaryotic translation initiation factor 4E family member 1B
chr18_+_35130416 0.19 ENSDART00000151595
si:ch211-195m9.3
si:ch211-195m9.3
chr5_-_26187097 0.19 ENSDART00000137027
ccdc125
coiled-coil domain containing 125
chr18_-_502722 0.19 ENSDART00000185757
sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
chr12_-_18577774 0.18 ENSDART00000078166
zdhhc4
zinc finger, DHHC-type containing 4
chr2_-_37743834 0.18 ENSDART00000088040
ENSDART00000191057
myo9b
myosin IXb
chr23_-_25050329 0.18 ENSDART00000140216
avpr2aa
arginine vasopressin receptor 2a, duplicate a
chr6_+_13506841 0.18 ENSDART00000032331
gmppab
GDP-mannose pyrophosphorylase Ab
chr9_+_22657221 0.18 ENSDART00000101765
si:dkey-189g17.2
si:dkey-189g17.2
chr3_-_31079186 0.18 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr7_-_27037990 0.18 ENSDART00000173561
nucb2a
nucleobindin 2a
chr25_+_16356083 0.17 ENSDART00000125925
ENSDART00000125444
tead1a
TEA domain family member 1a
chr19_-_3775503 0.17 ENSDART00000160358
si:dkey-206d17.16
si:dkey-206d17.16
chr4_-_1908179 0.17 ENSDART00000139586
ano6
anoctamin 6
chr11_-_12233 0.17 ENSDART00000173352
ENSDART00000173009
ENSDART00000102293
myg1
melanocyte proliferating gene 1
chr20_-_34670236 0.17 ENSDART00000033325
slc25a24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr22_+_24726066 0.17 ENSDART00000185534
BX539332.2

chr12_+_26538861 0.17 ENSDART00000152955
si:dkey-57h18.1
si:dkey-57h18.1
chr13_+_48359573 0.17 ENSDART00000161959
ENSDART00000165311
msh6
mutS homolog 6 (E. coli)

Network of associatons between targets according to the STRING database.

First level regulatory network of hmbox1a+zgc:91944

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 0.5 GO:0010935 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2 0.5 GO:0048785 hatching gland development(GO:0048785)
0.1 0.4 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.4 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138) toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.5 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 0.7 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.6 GO:0051883 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 0.6 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.3 GO:0032206 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.1 0.3 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.2 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.4 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.4 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.3 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0070207 iron ion transmembrane transport(GO:0034755) protein homotrimerization(GO:0070207)
0.0 0.2 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.0 0.2 GO:0046070 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 1.1 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.7 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.3 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.2 GO:0036268 swimming(GO:0036268)
0.0 0.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.5 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.4 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.2 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.1 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0071632 optomotor response(GO:0071632)
0.0 0.3 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 1.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.7 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.2 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.2 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.3 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.4 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.1 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.3 GO:0001843 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020)
0.0 2.1 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.0 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.5 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0044279 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.4 GO:0061702 inflammasome complex(GO:0061702)
0.1 2.1 GO:0031430 M band(GO:0031430)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 0.4 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 1.0 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.3 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.2 0.5 GO:0047760 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.1 0.5 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.2 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0032356 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.8 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779)
0.0 0.3 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 2.4 GO:0019900 kinase binding(GO:0019900)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 0.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein