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PRJNA207719: Tissue specific transcriptome profiling

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Results for hoxa11a

Z-value: 0.32

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Transcription factors associated with hoxa11a

Gene Symbol Gene ID Gene Info
hoxa11a
ENSDARG00000104162 homeobox A11a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa11adr11_v1_chr19_+_19737214_19737300-0.692.0e-01Click!

Activity profile of hoxa11a motif

Sorted Z-values of hoxa11a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_9586713 0.21 ENSDART00000145613
shank3b
SH3 and multiple ankyrin repeat domains 3b
chr7_+_31879649 0.21 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr8_-_14049404 0.21 ENSDART00000093117
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr7_+_31879986 0.19 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr10_+_33990572 0.17 ENSDART00000138547
fryb
furry homolog b (Drosophila)
chr6_-_40744720 0.14 ENSDART00000154916
ENSDART00000186922
p4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr7_+_20524064 0.13 ENSDART00000052917
slc3a2a
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr7_+_20966434 0.13 ENSDART00000185570
efnb3b
ephrin-B3b
chr18_+_18000887 0.13 ENSDART00000147797
si:ch211-212o1.2
si:ch211-212o1.2
chr12_+_33361948 0.10 ENSDART00000124982
fasn
fatty acid synthase
chr14_-_31060082 0.10 ENSDART00000111601
ENSDART00000161113
mbnl3
muscleblind-like splicing regulator 3
chr22_+_10646928 0.09 ENSDART00000038465
rassf1
Ras association (RalGDS/AF-6) domain family 1
chr16_-_6205790 0.08 ENSDART00000038495
ctnnb1
catenin (cadherin-associated protein), beta 1
chr5_+_36611128 0.08 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr4_-_20108833 0.08 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr12_-_26851726 0.08 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr24_+_21540842 0.08 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr6_-_53334259 0.08 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr3_-_27868183 0.08 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr24_-_40009446 0.07 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr20_-_44576949 0.07 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr25_-_18002937 0.07 ENSDART00000149696
cep290
centrosomal protein 290
chr9_-_3671911 0.07 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr5_-_35301800 0.07 ENSDART00000085142
map1b
microtubule-associated protein 1B
chr11_-_26832685 0.07 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr22_-_10502780 0.07 ENSDART00000136961
ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr14_-_48348973 0.06 ENSDART00000185822
CABZ01080056.1

chr2_-_13254821 0.06 ENSDART00000022621
kdsr
3-ketodihydrosphingosine reductase
chr9_-_23922011 0.06 ENSDART00000145734
col6a3
collagen, type VI, alpha 3
chr5_+_59397348 0.06 ENSDART00000175642
clip2
CAP-GLY domain containing linker protein 2
chr18_+_40993369 0.06 ENSDART00000141162
si:dkey-283j8.1
si:dkey-283j8.1
chr5_-_32489796 0.06 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr3_+_36284986 0.05 ENSDART00000059533
wipi1
WD repeat domain, phosphoinositide interacting 1
chr17_-_23727978 0.05 ENSDART00000079600
minpp1a
multiple inositol-polyphosphate phosphatase 1a
chr25_-_18002498 0.05 ENSDART00000158688
cep290
centrosomal protein 290
chr3_+_24190207 0.05 ENSDART00000034762
prr15la
proline rich 15-like a
chr4_+_39368978 0.05 ENSDART00000160640
si:dkey-261o4.1
si:dkey-261o4.1
chr15_+_36115955 0.05 ENSDART00000032702
sst1.2
somatostatin 1, tandem duplicate 2
chr5_+_59397739 0.05 ENSDART00000148659
clip2
CAP-GLY domain containing linker protein 2
chr2_-_13254594 0.05 ENSDART00000155671
kdsr
3-ketodihydrosphingosine reductase
chr16_-_24561354 0.05 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr15_+_8767650 0.04 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr18_-_2433011 0.04 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr2_-_43851915 0.04 ENSDART00000146493
zeb1a
zinc finger E-box binding homeobox 1a
chr11_+_43751263 0.04 ENSDART00000163843
zgc:153431
zgc:153431
chr22_+_2239974 0.04 ENSDART00000141993
znf1144
zinc finger protein 1144
chr7_-_43840418 0.04 ENSDART00000174592
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr2_-_43852207 0.04 ENSDART00000192627
zeb1a
zinc finger E-box binding homeobox 1a
chr12_-_34713690 0.03 ENSDART00000180807
bahcc1b
BAH domain and coiled-coil containing 1b
chr15_+_44093286 0.03 ENSDART00000114352
zgc:112998
zgc:112998
chr7_-_18508815 0.03 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr13_-_9875538 0.03 ENSDART00000041609
tm9sf3
transmembrane 9 superfamily member 3
chr1_+_36722122 0.03 ENSDART00000111566
tmem184c
transmembrane protein 184C
chr3_-_40254634 0.03 ENSDART00000154562
top3a
DNA topoisomerase III alpha
chr10_-_25561751 0.03 ENSDART00000147089
grik1a
glutamate receptor, ionotropic, kainate 1a
chr7_-_30280934 0.03 ENSDART00000126741
serf2
small EDRK-rich factor 2
chr22_-_33916620 0.03 ENSDART00000191276
CR974456.1

chr7_-_41014773 0.03 ENSDART00000013785
insig1
insulin induced gene 1
chr2_-_9259283 0.03 ENSDART00000133092
st6galnac5a
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5a
chr6_+_33885828 0.02 ENSDART00000179994
gpbp1l1
GC-rich promoter binding protein 1-like 1
chr6_+_49551614 0.02 ENSDART00000022581
rab22a
RAB22A, member RAS oncogene family
chr5_-_31856681 0.02 ENSDART00000187817
pkn3
protein kinase N3
chr25_-_19395156 0.02 ENSDART00000155335
map1ab
microtubule-associated protein 1Ab
chr24_-_31223232 0.02 ENSDART00000164155
alg14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr13_+_35472803 0.02 ENSDART00000011583
mkks
McKusick-Kaufman syndrome
chr24_+_20658760 0.02 ENSDART00000188362
sec22c
SEC22 homolog C, vesicle trafficking protein
chr16_-_47426482 0.02 ENSDART00000148631
ENSDART00000149723
sept7b
septin 7b
chr11_+_25560632 0.01 ENSDART00000033914
mbd1b
methyl-CpG binding domain protein 1b
chr18_+_40993196 0.01 ENSDART00000115111
si:dkey-283j8.1
si:dkey-283j8.1
chr25_+_3788443 0.01 ENSDART00000189747
chid1
chitinase domain containing 1
chr24_+_20658942 0.01 ENSDART00000142848
sec22c
SEC22 homolog C, vesicle trafficking protein
chr17_+_4368859 0.01 ENSDART00000055385
crls1
cardiolipin synthase 1
chr12_-_11560794 0.01 ENSDART00000149098
ENSDART00000169975
plekha1b
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b
chr7_-_30624435 0.01 ENSDART00000173828
rnf111
ring finger protein 111
chr11_+_25560072 0.01 ENSDART00000124131
ENSDART00000147179
mbd1b
methyl-CpG binding domain protein 1b
chr16_-_10316359 0.01 ENSDART00000104025
flot1b
flotillin 1b
chr9_-_29039506 0.01 ENSDART00000100744
tmem177
transmembrane protein 177
chr13_+_45431660 0.01 ENSDART00000099950
syf2
SYF2 pre-mRNA-splicing factor
chr11_-_21303946 0.01 ENSDART00000185786
RASSF5
si:dkey-85p17.3
chr13_+_29925397 0.00 ENSDART00000123482
cuedc2
CUE domain containing 2
chr15_-_14552101 0.00 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr17_+_44463230 0.00 ENSDART00000130311
naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr6_+_3730843 0.00 ENSDART00000019630
FO704755.1

chr18_-_17087138 0.00 ENSDART00000135597
zc3h18
zinc finger CCCH-type containing 18

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa11a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.0 0.2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0 0.2 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.1 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.0 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins