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PRJNA207719: Tissue specific transcriptome profiling

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Results for hoxa11b

Z-value: 1.06

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Transcription factors associated with hoxa11b

Gene Symbol Gene ID Gene Info
hoxa11b
ENSDARG00000007009 homeobox A11b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa11bdr11_v1_chr16_+_20904754_20904754-0.138.3e-01Click!

Activity profile of hoxa11b motif

Sorted Z-values of hoxa11b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_36034582 0.43 ENSDART00000133565
si:dkey-157l19.2
si:dkey-157l19.2
chr19_-_47571456 0.37 ENSDART00000158071
ENSDART00000165841
rrm2
ribonucleotide reductase M2 polypeptide
chr21_+_5531138 0.37 ENSDART00000163825
ly6m6
lymphocyte antigen 6 family member M6
chr13_-_37619159 0.32 ENSDART00000186348
zgc:152791
zgc:152791
chr24_-_10014512 0.30 ENSDART00000124341
ENSDART00000191630
zgc:171474
zgc:171474
chr21_+_11401247 0.28 ENSDART00000143952
cel.1
carboxyl ester lipase, tandem duplicate 1
chr16_-_45917322 0.28 ENSDART00000060822
afp4
antifreeze protein type IV
chr3_+_46763745 0.28 ENSDART00000185437
prkcsh
protein kinase C substrate 80K-H
chr10_-_8060573 0.28 ENSDART00000147104
ENSDART00000099030
si:ch211-251f6.6
si:ch211-251f6.6
chr9_+_52398531 0.26 ENSDART00000126215
dap1b
death associated protein 1b
chr2_-_44777592 0.25 ENSDART00000113351
ENSDART00000169310
ncapd2
non-SMC condensin I complex, subunit D2
chr24_-_38083378 0.24 ENSDART00000056381
crp2
C-reactive protein 2
chr5_-_42272517 0.24 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr22_+_6293563 0.24 ENSDART00000063416
rnasel2
ribonuclease like 2
chr10_+_26612321 0.23 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr3_-_32337653 0.23 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr20_+_26538137 0.23 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr20_-_29499363 0.23 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr3_+_46764022 0.23 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr12_-_25887864 0.22 ENSDART00000152983
si:dkey-193p11.2
si:dkey-193p11.2
chr8_+_52637507 0.22 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr12_-_4249000 0.22 ENSDART00000059298
zgc:92313
zgc:92313
chr5_-_4532516 0.22 ENSDART00000192398
cst14b.1
cystatin 14b, tandem duplicate 1
chr3_+_62161184 0.21 ENSDART00000090370
ENSDART00000192665
noxo1a
NADPH oxidase organizer 1a
chr11_-_19775182 0.21 ENSDART00000037894
namptb
nicotinamide phosphoribosyltransferase b
chr22_-_24297510 0.21 ENSDART00000163297
si:ch211-117l17.6
si:ch211-117l17.6
chr17_+_53294228 0.21 ENSDART00000158172
si:ch1073-416d2.3
si:ch1073-416d2.3
chr5_+_9037650 0.21 ENSDART00000158226
si:ch211-155m12.1
si:ch211-155m12.1
chr12_-_5728755 0.20 ENSDART00000105887
dlx4b
distal-less homeobox 4b
chr21_-_7035599 0.20 ENSDART00000139777
si:ch211-93g21.1
si:ch211-93g21.1
chr22_-_24818066 0.19 ENSDART00000143443
vtg6
vitellogenin 6
chr7_-_23768234 0.19 ENSDART00000173981
si:ch211-200p22.4
si:ch211-200p22.4
chr22_-_10158038 0.19 ENSDART00000047444
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr3_-_19495814 0.19 ENSDART00000162248
CU571315.3

chr3_+_32129632 0.19 ENSDART00000174522
zgc:109934
zgc:109934
chr21_+_20396858 0.19 ENSDART00000003299
ENSDART00000146615
zgc:103482
zgc:103482
chr3_-_26183699 0.19 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr13_+_27329556 0.19 ENSDART00000140085
mb21d1
Mab-21 domain containing 1
chr9_-_2892250 0.19 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr23_-_43718067 0.19 ENSDART00000015777
abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr9_-_48214216 0.18 ENSDART00000012938
phgdh
phosphoglycerate dehydrogenase
chr14_-_4120636 0.18 ENSDART00000059230
irf2
interferon regulatory factor 2
chr19_-_47571797 0.18 ENSDART00000166180
ENSDART00000168134
rrm2
ribonucleotide reductase M2 polypeptide
chr17_+_14711765 0.18 ENSDART00000012889
cx28.6
connexin 28.6
chr12_+_5102670 0.17 ENSDART00000166600
cep55l
centrosomal protein 55 like
chr1_-_6028876 0.17 ENSDART00000168117
si:ch1073-345a8.1
si:ch1073-345a8.1
chr15_+_1534644 0.17 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr23_+_2666944 0.17 ENSDART00000192861
CABZ01057928.1

chr16_+_23487051 0.17 ENSDART00000145496
icn2
ictacalcin 2
chr21_-_39024754 0.17 ENSDART00000056878
traf4b
tnf receptor-associated factor 4b
chr24_-_39826865 0.17 ENSDART00000089232
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr15_-_1843831 0.17 ENSDART00000156718
ENSDART00000154175
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr12_-_46252062 0.17 ENSDART00000153223
si:ch211-226h7.5
si:ch211-226h7.5
chr15_+_14856307 0.16 ENSDART00000167213
diabloa
diablo, IAP-binding mitochondrial protein a
chr5_-_29531948 0.16 ENSDART00000098360
arrdc1a
arrestin domain containing 1a
chr21_-_17296789 0.16 ENSDART00000192180
gfi1b
growth factor independent 1B transcription repressor
chr14_+_32918172 0.16 ENSDART00000182867
lnx2b
ligand of numb-protein X 2b
chr7_+_36041509 0.16 ENSDART00000162850
irx3a
iroquois homeobox 3a
chr19_-_2317558 0.16 ENSDART00000190300
sp8a
sp8 transcription factor a
chr21_+_13327527 0.16 ENSDART00000114294
snrpd3l
small nuclear ribonucleoprotein D3 polypeptide, like
chr10_+_6013076 0.16 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr1_-_9249943 0.16 ENSDART00000055011
zgc:136472
zgc:136472
chr3_-_32957702 0.16 ENSDART00000146586
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr20_+_26880668 0.15 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr3_+_6469754 0.15 ENSDART00000185809
NUP85 (1 of many)
nucleoporin 85
chr23_+_43718115 0.15 ENSDART00000149266
ENSDART00000149503
anapc10
anaphase promoting complex subunit 10
chr5_-_42883761 0.15 ENSDART00000167374
BX323596.2

chr2_+_58841181 0.15 ENSDART00000164102
cirbpa
cold inducible RNA binding protein a
chr20_+_19175031 0.15 ENSDART00000138028
blk
BLK proto-oncogene, Src family tyrosine kinase
chr16_-_46645396 0.15 ENSDART00000131485
tmem176l.2
transmembrane protein 176l.2
chr24_+_18286427 0.15 ENSDART00000055443
tpk1
thiamin pyrophosphokinase 1
chr20_+_52546186 0.15 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr9_+_41224100 0.15 ENSDART00000141792
stat1b
signal transducer and activator of transcription 1b
chr11_+_18130300 0.15 ENSDART00000169146
zgc:175135
zgc:175135
chr8_+_30709685 0.15 ENSDART00000133989
upb1
ureidopropionase, beta
chr15_-_4580763 0.15 ENSDART00000008170
rffl
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr1_+_44173245 0.15 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr2_+_52847049 0.14 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr21_-_19918286 0.14 ENSDART00000180816
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr2_+_35595454 0.14 ENSDART00000098734
cacybp
calcyclin binding protein
chr20_+_30610547 0.14 ENSDART00000122256
ccr6a
chemokine (C-C motif) receptor 6a
chr7_+_1579510 0.14 ENSDART00000190525
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr20_+_18702624 0.14 ENSDART00000185605
ENSDART00000019476
ENSDART00000152533
eif5
eukaryotic translation initiation factor 5
chr19_-_18626515 0.14 ENSDART00000160624
rps18
ribosomal protein S18
chr14_+_48862987 0.14 ENSDART00000167810
zgc:154054
zgc:154054
chr8_+_3379815 0.14 ENSDART00000155995
FUT9 (1 of many)
zgc:136963
chr15_-_563877 0.14 ENSDART00000128032
cbln18
cerebellin 18
chr24_+_17007407 0.14 ENSDART00000110652
zfx
zinc finger protein, X-linked
chr3_-_34089310 0.14 ENSDART00000151774
ighv5-5
immunoglobulin heavy variable 5-5
chr10_-_22127942 0.14 ENSDART00000133374
ponzr2
plac8 onzin related protein 2
chr9_+_20853894 0.14 ENSDART00000003648
wdr3
WD repeat domain 3
chr2_-_26596794 0.14 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr10_+_32050906 0.14 ENSDART00000137373
si:ch211-266i6.3
si:ch211-266i6.3
chr24_+_36840652 0.13 ENSDART00000088168
CABZ01055347.1

chr2_+_25839940 0.13 ENSDART00000139927
eif5a2
eukaryotic translation initiation factor 5A2
chr8_+_6576940 0.13 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr15_-_31027112 0.13 ENSDART00000100185
lgals9l4
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 4
chr21_-_2415808 0.13 ENSDART00000171179
si:ch211-241b2.5
si:ch211-241b2.5
chr10_+_15454745 0.13 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbin
erbb2 interacting protein
chr2_-_43151358 0.13 ENSDART00000061170
ENSDART00000056161
ftr15
finTRIM family, member 15
chr4_-_18954001 0.13 ENSDART00000144814
si:dkey-31f5.8
si:dkey-31f5.8
chr4_-_12723585 0.13 ENSDART00000185639
mgst1.2
microsomal glutathione S-transferase 1.2
chr3_-_55104310 0.13 ENSDART00000101713
hbba1
hemoglobin, beta adult 1
chr9_-_34269066 0.13 ENSDART00000059955
ildr1b
immunoglobulin-like domain containing receptor 1b
chr12_-_46112892 0.13 ENSDART00000187128
ENSDART00000114268
zgc:153932
zgc:153932
chr11_+_18157260 0.13 ENSDART00000144659
zgc:173545
zgc:173545
chr5_-_57723929 0.12 ENSDART00000144237
gig2p
grass carp reovirus (GCRV)-induced gene 2p
chr5_-_54712159 0.12 ENSDART00000149207
ccnb1
cyclin B1
chr1_+_45056371 0.12 ENSDART00000073689
ENSDART00000167309
btr01
bloodthirsty-related gene family, member 1
chr19_-_27550768 0.12 ENSDART00000142313
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr9_+_23770666 0.12 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr5_-_1274794 0.12 ENSDART00000167337
ENSDART00000125247
ciz1a
cdkn1a interacting zinc finger protein 1a
chr1_-_56176976 0.12 ENSDART00000052688
c3a.1
complement component c3a, duplicate 1
chr6_+_3693441 0.12 ENSDART00000065256
ppig
peptidylprolyl isomerase G (cyclophilin G)
chr13_+_36585399 0.12 ENSDART00000030211
gmfb
glia maturation factor, beta
chr18_+_31056645 0.12 ENSDART00000159316
mvda
mevalonate (diphospho) decarboxylase a
chr19_-_617246 0.12 ENSDART00000062551
cyp51
cytochrome P450, family 51
chr14_+_14841685 0.12 ENSDART00000158291
ENSDART00000162039
slbp
stem-loop binding protein
chr7_+_49681040 0.12 ENSDART00000176372
ENSDART00000192172
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr18_-_3520358 0.12 ENSDART00000181412
capn5a
calpain 5a
chr21_+_33459524 0.12 ENSDART00000053205
cd74b
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr21_-_32781612 0.12 ENSDART00000031028
cnot6a
CCR4-NOT transcription complex, subunit 6a
chr20_-_25522911 0.12 ENSDART00000063058
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr8_+_50190742 0.12 ENSDART00000099863
slc25a37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr21_+_16980141 0.12 ENSDART00000101241
aqp3b
aquaporin 3b
chr8_-_12432604 0.12 ENSDART00000133350
ENSDART00000140699
ENSDART00000101174
traf1
TNF receptor-associated factor 1
chr2_-_59145027 0.12 ENSDART00000128320
FO834803.1

chr11_+_14284866 0.11 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr6_-_54290227 0.11 ENSDART00000050483
SPDEF
SAM pointed domain containing ETS transcription factor
chr20_+_29565906 0.11 ENSDART00000062383
ywhaqa
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
chr17_+_39741926 0.11 ENSDART00000154996
ENSDART00000154599
si:dkey-229e3.2
si:dkey-229e3.2
chr12_-_30540699 0.11 ENSDART00000167712
ENSDART00000102464
zgc:153920
zgc:153920
chr3_-_26184018 0.11 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr10_-_10969596 0.11 ENSDART00000092011
exd3
exonuclease 3'-5' domain containing 3
chr19_-_30447611 0.11 ENSDART00000073705
ENSDART00000048977
ENSDART00000191237
abcf1
ATP-binding cassette, sub-family F (GCN20), member 1
chr2_+_25839650 0.11 ENSDART00000134077
ENSDART00000140804
eif5a2
eukaryotic translation initiation factor 5A2
chr6_-_42388608 0.11 ENSDART00000049425
sec61a1l
Sec61 translocon alpha 1 subunit, like
chr7_-_57637779 0.11 ENSDART00000028017
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr10_-_10969444 0.11 ENSDART00000138041
exd3
exonuclease 3'-5' domain containing 3
chr17_+_31221761 0.11 ENSDART00000155580
ccdc32
coiled-coil domain containing 32
chr14_-_36862745 0.11 ENSDART00000109293
rnf130
ring finger protein 130
chr22_+_10440991 0.11 ENSDART00000064805
cenpp
centromere protein P
chr8_+_39724138 0.11 ENSDART00000009323
pla2g1b
phospholipase A2, group IB (pancreas)
chr24_-_1985007 0.11 ENSDART00000189870
PARD3 (1 of many)
par-3 family cell polarity regulator
chr16_+_35916371 0.11 ENSDART00000167208
sh3d21
SH3 domain containing 21
chr17_+_25331576 0.11 ENSDART00000157309
tmem54a
transmembrane protein 54a
chr22_+_34616151 0.11 ENSDART00000155399
ENSDART00000104705
si:ch1073-214b20.2
si:ch1073-214b20.2
chr3_-_4501026 0.11 ENSDART00000163052
zgc:162198
zgc:162198
chr7_-_26457208 0.11 ENSDART00000173519
zgc:172079
zgc:172079
chr14_+_31496543 0.11 ENSDART00000170683
phf6
PHD finger protein 6
chr10_-_1276046 0.11 ENSDART00000169779
pdlim5b
PDZ and LIM domain 5b
chr25_-_21031007 0.11 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr2_-_10877765 0.10 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr22_+_6254194 0.10 ENSDART00000112388
ENSDART00000135176
rnasel4
ribonuclease like 4
chr25_+_35913614 0.10 ENSDART00000022437
gpia
glucose-6-phosphate isomerase a
chr7_-_16598212 0.10 ENSDART00000128488
e2f8
E2F transcription factor 8
chr16_-_30421275 0.10 ENSDART00000003752
cct3
chaperonin containing TCP1, subunit 3 (gamma)
chr10_-_35410518 0.10 ENSDART00000048430
gabrr3a
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr11_+_575665 0.10 ENSDART00000122133
mkrn2os.1
MKRN2 opposite strand, tandem duplicate 1
chr3_+_32139666 0.10 ENSDART00000109791
zgc:92066
zgc:92066
chr25_+_3994823 0.10 ENSDART00000154020
eps8l2
EPS8 like 2
chr11_+_16166117 0.10 ENSDART00000109585
ENSDART00000135724
hmces
5-hydroxymethylcytosine (hmC) binding, ES cell-specific
chr2_+_36112273 0.10 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr5_+_66433287 0.10 ENSDART00000170757
kntc1
kinetochore associated 1
chr6_-_9282080 0.10 ENSDART00000159506
ccdc14
coiled-coil domain containing 14
chr3_+_32135037 0.10 ENSDART00000110490
BX511021.1

chr21_-_14826066 0.10 ENSDART00000067001
noc4l
nucleolar complex associated 4 homolog
chr8_+_3405612 0.10 ENSDART00000163437
zgc:112433
zgc:112433
chr7_+_73801377 0.10 ENSDART00000184051
si:ch73-252p3.1
si:ch73-252p3.1
chr8_+_23152244 0.10 ENSDART00000036801
ENSDART00000184298
slc17a9a
solute carrier family 17 (vesicular nucleotide transporter), member 9a
chr8_+_39674707 0.10 ENSDART00000126301
ENSDART00000040330
prkab1b
protein kinase, AMP-activated, beta 1 non-catalytic subunit, b
chr1_-_53468160 0.10 ENSDART00000143349
zgc:66455
zgc:66455
chr18_+_29898955 0.10 ENSDART00000064080
cenpn
centromere protein N
chr7_-_18508815 0.10 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr20_-_49889111 0.10 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr12_+_3723650 0.10 ENSDART00000179922
ENSDART00000152482
ENSDART00000108771
pagr1
PAXIP1 associated glutamate-rich protein 1
chr7_+_24522308 0.10 ENSDART00000173542
btr09
bloodthirsty-related gene family, member 9
chr22_-_10440688 0.10 ENSDART00000111962
nol8
nucleolar protein 8
chr8_+_45334255 0.10 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr21_-_3007412 0.09 ENSDART00000190839
CKS2
zgc:86839
chr5_-_38107741 0.09 ENSDART00000156853
si:ch211-284e13.14
si:ch211-284e13.14
chr17_+_45817527 0.09 ENSDART00000035152
kif26ab
kinesin family member 26Ab
chr17_-_31611692 0.09 ENSDART00000141480
si:dkey-170l10.1
si:dkey-170l10.1
chr17_+_27456804 0.09 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
ctsl.1
cathepsin L.1
chr20_-_34670236 0.09 ENSDART00000033325
slc25a24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr7_+_2228276 0.09 ENSDART00000064294
si:dkey-187j14.4
si:dkey-187j14.4
chr5_-_33281046 0.09 ENSDART00000051344
ENSDART00000138116
surf6
surfeit 6
chr3_+_49097775 0.09 ENSDART00000169185
zgc:123284
zgc:123284
chr3_+_32105175 0.09 ENSDART00000113789
zgc:198419
zgc:198419
chr6_-_18228358 0.09 ENSDART00000167937
p4hb
prolyl 4-hydroxylase, beta polypeptide
chr1_-_13989643 0.09 ENSDART00000191046
elf2b
E74-like factor 2b (ets domain transcription factor)
chr18_+_6558338 0.09 ENSDART00000110892
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr12_-_20616160 0.09 ENSDART00000105362
snx11
sorting nexin 11
chr13_-_14908999 0.09 ENSDART00000112771
ap5s1
adaptor-related protein complex 5, sigma 1 subunit
chr3_-_15999501 0.09 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr23_+_10146542 0.09 ENSDART00000048073
zgc:171775
zgc:171775
chr16_-_32304764 0.09 ENSDART00000143859
ENSDART00000134381
mms22l
MMS22-like, DNA repair protein
chr6_+_45918981 0.09 ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr23_+_11285662 0.09 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr22_-_11661724 0.09 ENSDART00000025198
mettl21a
methyltransferase like 21A

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa11b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.2 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.2 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.2 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.1 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:1902230 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:0035739 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.1 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.0 0.3 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.0 0.1 GO:0071047 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.1 GO:1990564 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.0 0.1 GO:0097065 anterior head development(GO:0097065)
0.0 0.1 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.0 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.0 GO:0030238 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.0 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.1 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.0 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.2 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.3 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.0 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.0 0.1 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.0 GO:0030910 olfactory placode formation(GO:0030910)
0.0 0.2 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.0 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.0 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.0 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.2 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.3 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.2 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.3 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.0 GO:0097189 apoptotic body(GO:0097189)
0.0 0.0 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.0 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.0 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.0 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.0 GO:0005880 nuclear microtubule(GO:0005880)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.3 GO:0070513 death domain binding(GO:0070513)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0030975 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.2 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.1 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.0 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.0 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.0 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.0 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation