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PRJNA207719: Tissue specific transcriptome profiling

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Results for hoxb7a

Z-value: 0.49

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Transcription factors associated with hoxb7a

Gene Symbol Gene ID Gene Info
hoxb7a
ENSDARG00000056030 homeobox B7a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb7adr11_v1_chr3_+_23691847_236918470.029.7e-01Click!

Activity profile of hoxb7a motif

Sorted Z-values of hoxb7a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_69019851 0.40 ENSDART00000162891
CABZ01057488.1

chr2_-_1486023 0.33 ENSDART00000113774
si:ch211-188c16.1
si:ch211-188c16.1
chr10_-_21362071 0.29 ENSDART00000125167
avd
avidin
chr13_-_10945288 0.26 ENSDART00000114315
ENSDART00000164667
ENSDART00000159482
abcg8
ATP-binding cassette, sub-family G (WHITE), member 8
chr10_-_21362320 0.24 ENSDART00000189789
avd
avidin
chr7_+_21272833 0.20 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr13_+_10945337 0.20 ENSDART00000091845
abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr18_+_14619544 0.19 ENSDART00000010821
utp4
UTP4, small subunit processome component
chr24_+_16985181 0.19 ENSDART00000135580
eif2s3
eukaryotic translation initiation factor 2, subunit 3 gamma
chr12_-_35830625 0.18 ENSDART00000180028
CU459056.1

chr4_-_9891874 0.18 ENSDART00000067193
adm2a
adrenomedullin 2a
chr22_-_22301672 0.18 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr4_-_13548806 0.17 ENSDART00000067155
il22
interleukin 22
chr6_+_25257728 0.17 ENSDART00000162581
kyat3
kynurenine aminotransferase 3
chr10_-_31015535 0.17 ENSDART00000146116
panx3
pannexin 3
chr22_-_27296889 0.16 ENSDART00000155724
si:dkey-208m12.3
si:dkey-208m12.3
chr18_+_45781516 0.16 ENSDART00000168840
rpl35a
ribosomal protein L35a
chr25_-_35599887 0.16 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr24_-_38657683 0.16 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr18_+_45781115 0.15 ENSDART00000151699
ENSDART00000179887
rpl35a
ribosomal protein L35a
chr9_+_24008879 0.15 ENSDART00000190419
ENSDART00000191843
ENSDART00000148226
mlphb
melanophilin b
chr12_-_4243268 0.15 ENSDART00000131275
zgc:92313
zgc:92313
chr4_+_16715267 0.14 ENSDART00000143849
pkp2
plakophilin 2
chr10_-_13343831 0.14 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr7_+_7696665 0.12 ENSDART00000091099
ino80b
INO80 complex subunit B
chr9_+_1139378 0.12 ENSDART00000170033
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr6_-_43677125 0.12 ENSDART00000150128
foxp1b
forkhead box P1b
chr5_-_30620625 0.12 ENSDART00000098273
tcnl
transcobalamin like
chr8_+_25034544 0.12 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr24_+_7800486 0.12 ENSDART00000145504
ptprh
protein tyrosine phosphatase, receptor type, h
chr25_+_13620555 0.11 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr22_-_22301929 0.11 ENSDART00000142027
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr5_+_71802014 0.11 ENSDART00000124939
ENSDART00000097164
LHX3
LIM homeobox 3
chr23_+_28809002 0.11 ENSDART00000134121
ENSDART00000183661
pex14
peroxisomal biogenesis factor 14
chr5_-_16218777 0.11 ENSDART00000141698
kremen1
kringle containing transmembrane protein 1
chr3_-_36602379 0.10 ENSDART00000161501
ENSDART00000162396
rrn3
RRN3 homolog, RNA polymerase I transcription factor
chr3_-_50443607 0.10 ENSDART00000074036
rcvrna
recoverin a
chr12_+_16168342 0.10 ENSDART00000079326
ENSDART00000170024
lrp2b
low density lipoprotein receptor-related protein 2b
chr5_+_34623107 0.10 ENSDART00000184126
enc1
ectodermal-neural cortex 1
chr3_-_36602069 0.10 ENSDART00000165414
rrn3
RRN3 homolog, RNA polymerase I transcription factor
chr17_+_20589553 0.10 ENSDART00000154447
si:ch73-288o11.4
si:ch73-288o11.4
chr13_-_5252559 0.09 ENSDART00000181652
si:dkey-78p8.1
si:dkey-78p8.1
chr20_-_45812144 0.09 ENSDART00000147897
ENSDART00000147637
fermt1
fermitin family member 1
chr6_+_7414215 0.09 ENSDART00000049339
sox21a
SRY (sex determining region Y)-box 21a
chr17_+_51682429 0.09 ENSDART00000004379
nol10
nucleolar protein 10
chr12_+_20641471 0.08 ENSDART00000133654
calcoco2
calcium binding and coiled-coil domain 2
chr12_+_48803098 0.08 ENSDART00000074768
ppifb
peptidylprolyl isomerase Fb
chr22_-_19102256 0.08 ENSDART00000171866
ENSDART00000166295
polrmt
polymerase (RNA) mitochondrial (DNA directed)
chr20_+_15600167 0.08 ENSDART00000171991
faslg
Fas ligand (TNF superfamily, member 6)
chr10_-_26744131 0.08 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr17_+_30369396 0.08 ENSDART00000076611
greb1
growth regulation by estrogen in breast cancer 1
chr2_-_36500347 0.07 ENSDART00000110528
BX901889.1

chr24_-_36680261 0.07 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr23_+_39462208 0.07 ENSDART00000136707
mical1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr8_-_13046089 0.07 ENSDART00000137784
si:dkey-208b23.5
si:dkey-208b23.5
chr4_-_63165848 0.07 ENSDART00000183789
CR450780.1

chr23_+_39461989 0.07 ENSDART00000184761
mical1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr4_-_2545310 0.07 ENSDART00000150619
ENSDART00000140760
e2f7
E2F transcription factor 7
chr8_-_12867434 0.06 ENSDART00000081657
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr24_+_13316737 0.06 ENSDART00000191658
SBSPON
somatomedin B and thrombospondin type 1 domain containing
chr2_+_35728033 0.06 ENSDART00000002094
ankrd45
ankyrin repeat domain 45
chr18_-_33080454 0.06 ENSDART00000191907
v2ra18
vomeronasal 2 receptor, a18
chr7_+_7048245 0.06 ENSDART00000001649
actn3b
actinin alpha 3b
chr23_+_4709607 0.06 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr7_-_33960170 0.05 ENSDART00000180766
skor1a
SKI family transcriptional corepressor 1a
chr14_+_16287968 0.05 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr15_-_40246396 0.05 ENSDART00000063777
kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr4_+_70151160 0.05 ENSDART00000111816
si:dkey-3h2.4
si:dkey-3h2.4
chr15_+_857148 0.05 ENSDART00000156949
si:dkey-7i4.13
si:dkey-7i4.13
chr6_+_24398907 0.05 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr4_+_77971104 0.05 ENSDART00000188609
zgc:113921
zgc:113921
chr8_-_12867128 0.05 ENSDART00000142201
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr5_+_56023186 0.04 ENSDART00000156230
fzd9a
frizzled class receptor 9a
chr6_+_21992820 0.04 ENSDART00000147507
thumpd3
THUMP domain containing 3
chr20_-_9095105 0.04 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr17_+_25481466 0.04 ENSDART00000139451
aim1a
crystallin beta-gamma domain containing 1a
chr2_-_7246848 0.04 ENSDART00000146434
zgc:153115
zgc:153115
chr17_+_16090436 0.03 ENSDART00000136059
ENSDART00000138734
znf395a
zinc finger protein 395a
chr11_-_2838699 0.03 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr12_+_20641102 0.03 ENSDART00000152964
calcoco2
calcium binding and coiled-coil domain 2
chr11_+_705727 0.03 ENSDART00000165366
timp4.2
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr21_+_8276989 0.02 ENSDART00000028265
nr5a1b
nuclear receptor subfamily 5, group A, member 1b
chr23_-_25779995 0.02 ENSDART00000110670
si:dkey-21c19.3
si:dkey-21c19.3
chr18_+_2228737 0.02 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr10_+_11261576 0.02 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr20_-_46128590 0.02 ENSDART00000123744
taar1b
trace amine associated receptor 1b
chr2_+_15048410 0.01 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr12_+_47698356 0.01 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr6_+_9898683 0.01 ENSDART00000005573
tmem237b
transmembrane protein 237b

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb7a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.2 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.5 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines