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PRJNA207719: Tissue specific transcriptome profiling

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Results for hoxb8a+hoxb8b

Z-value: 0.70

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Transcription factors associated with hoxb8a+hoxb8b

Gene Symbol Gene ID Gene Info
ENSDARG00000054025 homeobox B8b
ENSDARG00000056027 homeobox B8a
ENSDARG00000111056 homeobox B8b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb8bdr11_v1_chr12_+_27117609_271176090.049.5e-01Click!
hoxb8adr11_v1_chr3_+_23687909_23687909-0.019.8e-01Click!

Activity profile of hoxb8a+hoxb8b motif

Sorted Z-values of hoxb8a+hoxb8b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_13792490 0.84 ENSDART00000136754
cadherin 13, H-cadherin (heart)
chr16_+_10776688 0.71 ENSDART00000161969
ENSDART00000172657
ATPase Na+/K+ transporting subunit alpha 3b
chr24_-_28259127 0.48 ENSDART00000149589
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr1_+_16144615 0.47 ENSDART00000054707
tumor suppressor candidate 3
chr3_-_34337969 0.46 ENSDART00000151634
trinucleotide repeat containing 6C1
chr12_-_11457625 0.45 ENSDART00000012318
HtrA serine peptidase 1b
chr10_-_39011514 0.44 ENSDART00000075123
Purkinje cell protein 4a
chr25_+_15647750 0.41 ENSDART00000137375
spondin 1b
chr13_-_5569562 0.40 ENSDART00000102576
Meis homeobox 1 b
chr9_-_20372977 0.38 ENSDART00000113418
immunoglobulin superfamily, member 3
chr11_+_6819050 0.37 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr11_+_36243774 0.35 ENSDART00000023323
zgc:172270
chr1_-_23157583 0.34 ENSDART00000144208
adhesion G protein-coupled receptor L3.1
chr13_+_22316746 0.33 ENSDART00000188968
ubiquitin specific peptidase 54a
chr2_+_33368414 0.33 ENSDART00000077462
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr21_+_43669943 0.32 ENSDART00000136025
trimethyllysine hydroxylase, epsilon
chr4_+_7391110 0.32 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr20_+_20672163 0.31 ENSDART00000027758
reticulon 1b
chr15_+_4632782 0.31 ENSDART00000156012
si:dkey-35i13.1
chr13_-_5568928 0.31 ENSDART00000192679
Meis homeobox 1 b
chr25_+_15647993 0.30 ENSDART00000186578
ENSDART00000031828
spondin 1b
chr10_+_23060391 0.30 ENSDART00000079711
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr18_+_21408794 0.30 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr18_-_38088099 0.29 ENSDART00000146120
leucine zipper protein 2
chr22_+_18389271 0.28 ENSDART00000088270
YjeF N-terminal domain containing 3
chr6_+_52804267 0.28 ENSDART00000065681
matrilin 4
chr19_+_12444943 0.28 ENSDART00000135706
low density lipoprotein receptor class A domain containing 4a
chr13_-_30027730 0.27 ENSDART00000044009
stearoyl-CoA desaturase b
chr3_-_16227490 0.27 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
calcium channel, voltage-dependent, beta 1 subunit
chr2_-_9646857 0.27 ENSDART00000056901
zgc:153615
chr20_-_29420713 0.27 ENSDART00000147464
ryanodine receptor 3
chr18_+_10840071 0.26 ENSDART00000014496
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr11_-_13341483 0.25 ENSDART00000164978
microtubule associated serine/threonine kinase 3b
chr7_+_31879649 0.25 ENSDART00000099789
myosin binding protein C, cardiac
chr2_-_54039293 0.25 ENSDART00000166013
abhydrolase domain containing 8a
chr2_+_37480669 0.24 ENSDART00000029801
signal peptide peptidase-like 2
chr8_-_52413032 0.24 ENSDART00000183039

chr11_-_3959889 0.24 ENSDART00000159683
polybromo 1
chr10_+_26571174 0.23 ENSDART00000148617
ENSDART00000112956
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr23_+_12545114 0.23 ENSDART00000105283
ENSDART00000166990
si:zfos-452g4.1
chr12_+_39685485 0.23 ENSDART00000163403

chr3_+_59784632 0.22 ENSDART00000084729
platelet/endothelial cell adhesion molecule 1
chr24_-_6898302 0.22 ENSDART00000158646
dipeptidyl-peptidase 6a
chr16_+_46401576 0.22 ENSDART00000130264
rapunzel
chr11_-_13341051 0.21 ENSDART00000121872
microtubule associated serine/threonine kinase 3b
chr3_-_16227683 0.21 ENSDART00000111707
calcium channel, voltage-dependent, beta 1 subunit
chr11_-_44030962 0.21 ENSDART00000171910

chr23_-_32304650 0.21 ENSDART00000143772
ENSDART00000085642
ENSDART00000188989
diacylglycerol kinase, alpha a
chr7_+_31879986 0.20 ENSDART00000138491
myosin binding protein C, cardiac
chr6_-_53281518 0.20 ENSDART00000157621
RNA binding motif protein 5
chr20_+_32152355 0.20 ENSDART00000152904
ENSDART00000139507
sestrin 1
chr1_-_19215336 0.20 ENSDART00000162949
ENSDART00000170680
protein tyrosine phosphatase, receptor type, D, b
chr21_-_23308286 0.20 ENSDART00000184419
zinc finger and BTB domain containing 16a
chr13_+_23282549 0.20 ENSDART00000101134
KH domain containing, RNA binding, signal transduction associated 2
chr7_+_38811800 0.19 ENSDART00000052322
zgc:110699
chr5_+_61361815 0.19 ENSDART00000009507
GATS protein-like 2
chr9_+_42066030 0.19 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr1_-_9277986 0.19 ENSDART00000146065
ENSDART00000114876
ENSDART00000132812
ubinuclein 1
chr8_-_34051548 0.18 ENSDART00000105204
pre-B-cell leukemia homeobox 3b
chr23_-_11870962 0.18 ENSDART00000143481
si:dkey-178k16.1
chr4_+_12292274 0.17 ENSDART00000061070
ENSDART00000150786
makorin, ring finger protein, 1
chr8_-_34052019 0.17 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pre-B-cell leukemia homeobox 3b
chr11_-_3959477 0.17 ENSDART00000045971
polybromo 1
chr5_-_24869213 0.17 ENSDART00000112287
ENSDART00000144635
growth arrest-specific 2 like 1
chr24_+_41915878 0.17 ENSDART00000171523
transmembrane protein 200C
chr4_+_13810811 0.17 ENSDART00000067168
PDZ domain containing ring finger 4
chr18_+_27218737 0.16 ENSDART00000111450
pleckstrin homology domain containing, family A member 7a
chr24_+_18948665 0.16 ENSDART00000106186
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr9_+_38075851 0.16 ENSDART00000135314
calcium channel, voltage-dependent, beta 4a subunit
chr24_-_40009446 0.16 ENSDART00000087422
amine oxidase, copper containing 1
chr21_+_22878991 0.16 ENSDART00000186399
PCF11 cleavage and polyadenylation factor subunit
chr9_-_23217196 0.16 ENSDART00000083567
kinesin family member 5C
chr1_+_23784905 0.16 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit homolog 2 (Drosophila)
chr15_+_8767650 0.16 ENSDART00000033871
adaptor-related protein complex 2, sigma 1 subunit
chr10_+_36026576 0.16 ENSDART00000193786
high mobility group box 1a
chr18_-_8857137 0.15 ENSDART00000126331
proline-rich transmembrane protein 4
chr21_-_31241254 0.15 ENSDART00000065365
tyrosylprotein sulfotransferase 1, like
chr2_+_47623202 0.15 ENSDART00000154465
si:ch211-165b10.3
chr7_-_18598661 0.15 ENSDART00000182109
si:ch211-119e14.2
chr19_+_37925616 0.15 ENSDART00000148348
neurexophilin 1
chr1_-_8980665 0.14 ENSDART00000148182
si:ch73-191k20.3
chr18_+_783936 0.14 ENSDART00000193357
ribonuclease P and MRP subunit p25, b
chr24_+_5840258 0.14 ENSDART00000087034
transient receptor potential cation channel, subfamily C, member 1
chr24_+_24461341 0.14 ENSDART00000147658
basic helix-loop-helix family, member e22
chr2_+_35240764 0.14 ENSDART00000015827
tenascin R (restrictin, janusin)
chr6_+_14949950 0.14 ENSDART00000149202
ENSDART00000149949
POU class 3 homeobox 3b
chr20_+_54274431 0.13 ENSDART00000099338
ARP10 actin related protein 10 homolog
chr21_-_26918901 0.13 ENSDART00000100685
leucine rich repeat and fibronectin type III domain containing 4a
chr2_+_38608290 0.13 ENSDART00000159066
cadherin 24, type 2b
chr4_+_10754802 0.13 ENSDART00000181470
stabilin 2
chr20_-_8443425 0.13 ENSDART00000083908
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr7_-_46777876 0.13 ENSDART00000193954
teashirt zinc finger homeobox 3b
chr12_+_22404108 0.13 ENSDART00000153055
high density lipoprotein binding protein b
chr17_-_26507289 0.13 ENSDART00000155616
coiled-coil serine-rich protein 2a
chr20_-_7293837 0.13 ENSDART00000100060
desmocollin 2 like
chr20_+_20751425 0.13 ENSDART00000177048
protein phosphatase 1, regulatory subunit 13Bb
chr10_-_27741793 0.12 ENSDART00000129369
ENSDART00000192440
ENSDART00000189808
ENSDART00000138149
autism susceptibility candidate 2a
si:dkey-33o22.1
chr7_-_40959867 0.12 ENSDART00000174009
RNA binding motif protein 33a
chr15_+_28116129 0.12 ENSDART00000185157
unc-119 homolog a (C. elegans)
chr5_-_34185115 0.12 ENSDART00000192771
fibrinogen C domain containing 1
chr13_-_38730267 0.12 ENSDART00000157524
LMBR1 domain containing 1
chr1_-_26071535 0.12 ENSDART00000185187
programmed cell death 4a
chr2_+_3809226 0.12 ENSDART00000147261
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr14_+_25465346 0.11 ENSDART00000173436
si:dkey-280e21.3
chr18_+_50890749 0.11 ENSDART00000174109
si:ch1073-450f2.1
chr10_+_31244619 0.11 ENSDART00000145562
ENSDART00000184412
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr24_+_24461558 0.11 ENSDART00000182424
basic helix-loop-helix family, member e22
chr1_-_47431453 0.11 ENSDART00000101104
gap junction protein, alpha 5b
chr1_+_26071869 0.10 ENSDART00000059264
MAX dimerization protein 4
chr17_-_38778826 0.10 ENSDART00000168182
ENSDART00000124041
ENSDART00000136921
D-glutamate cyclase
chr9_-_39547907 0.10 ENSDART00000163635
erb-b2 receptor tyrosine kinase 4b
chr15_-_5467477 0.10 ENSDART00000123839
arrestin, beta 1
chr12_-_3756405 0.10 ENSDART00000150839
family with sequence similarity 57, member Bb
chr17_-_19626357 0.10 ENSDART00000011432
receptor accessory protein 3a
chr19_+_5480327 0.10 ENSDART00000148794
junction plakoglobin b
chr12_+_17201522 0.10 ENSDART00000014536
ENSDART00000152452
renalase, FAD-dependent amine oxidase
chr8_-_20380750 0.10 ENSDART00000113910
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr16_+_17389116 0.10 ENSDART00000103750
ENSDART00000173448
family with sequence similarity 131, member Bb
chr14_+_35237613 0.10 ENSDART00000163465
early B cell factor 3a
chr7_+_13382852 0.10 ENSDART00000166318
diacylglycerol lipase, alpha
chr24_+_28953089 0.10 ENSDART00000153761
RNA-binding region (RNP1, RRM) containing 3
chr19_-_3123963 0.10 ENSDART00000122816
si:ch211-80h18.1
chr14_+_6954579 0.10 ENSDART00000060998
NME/NM23 family member 5
chr6_+_23931236 0.09 ENSDART00000166079
growth arrest and DNA-damage-inducible, alpha, b
chr17_+_19626479 0.09 ENSDART00000044993
ENSDART00000131863
regulator of G protein signaling 7a
chr7_+_12927944 0.09 ENSDART00000027329
ferritin, heavy polypeptide 1a
chr1_+_55104376 0.09 ENSDART00000150492
aftiphilin a
chr21_-_22812417 0.09 ENSDART00000079151
ENSDART00000112175
transient receptor potential cation channel, subfamily C, member 6a
chr2_-_24962820 0.09 ENSDART00000182767
helicase-like transcription factor
chr12_-_38548299 0.09 ENSDART00000153374
si:dkey-1f1.3
chr18_+_17959681 0.09 ENSDART00000142700
zinc finger protein 423
chr2_+_31665836 0.08 ENSDART00000135411
ENSDART00000143914
si:ch211-106h4.12
chr13_+_15581270 0.08 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
MAP/microtubule affinity-regulating kinase 3a
chr10_+_43039947 0.08 ENSDART00000193434
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr5_-_32813933 0.08 ENSDART00000050041
ENSDART00000135864
protein phosphatase 2 phosphatase activator
chr1_+_35494837 0.08 ENSDART00000140724
GRB2-associated binding protein 1
chr20_-_19590378 0.08 ENSDART00000152588
brain and acute leukemia, cytoplasmic b
chr9_+_19529951 0.07 ENSDART00000125416
pbx/knotted 1 homeobox 1.1
chr2_+_10821127 0.07 ENSDART00000145770
ENSDART00000174629
ENSDART00000081094
glomulin, FKBP associated protein a
chr20_-_2949028 0.07 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cyclin-dependent kinase 19
chr3_-_33574576 0.07 ENSDART00000184881

chr1_+_51191049 0.07 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
BTB (POZ) domain containing 3a
chr14_+_36231126 0.07 ENSDART00000141766
ELOVL fatty acid elongase 6
chr8_+_20503842 0.07 ENSDART00000100328
casein kinase 1, gamma 2b
chr10_-_8197049 0.07 ENSDART00000129467
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr14_+_4796168 0.07 ENSDART00000041468
adaptor-related protein complex 1 associated regulatory protein
chr2_-_10188598 0.07 ENSDART00000189122
diencephalon/mesencephalon homeobox 1a
chr19_-_3876877 0.06 ENSDART00000163711
thyroid hormone receptor associated protein 3b
chr4_+_20954929 0.06 ENSDART00000143674
neuron navigator 3
chr12_-_28848015 0.06 ENSDART00000153200
si:ch211-194k22.8
chr14_+_35024521 0.06 ENSDART00000158634
ENSDART00000170631
early B cell factor 3a
chr15_-_34567370 0.06 ENSDART00000099793
sclerostin domain containing 1a
chr7_-_69983948 0.06 ENSDART00000185827
potassium voltage-gated channel interacting protein 4
chr4_-_4261673 0.06 ENSDART00000150694
CD9 molecule b
chr10_-_45210184 0.06 ENSDART00000167128
poly (ADP-ribose) glycohydrolase, like
chr13_+_36622100 0.06 ENSDART00000133198
si:ch211-67f24.7
chr4_+_21867522 0.06 ENSDART00000140400
acyl-CoA synthetase short chain family member 3
chr4_+_17655872 0.06 ENSDART00000066999
WASH complex subunit 3
chr4_-_30362840 0.06 ENSDART00000165929
zinc finger protein 1083
chr15_-_15968883 0.06 ENSDART00000166583
ENSDART00000154042
synergin, gamma
chr24_-_7826489 0.05 ENSDART00000112777
si:dkey-197c15.6
chr19_-_17303500 0.05 ENSDART00000162355
splicing factor 3a, subunit 3
chr11_+_43419809 0.05 ENSDART00000172982
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr13_-_22961605 0.05 ENSDART00000143112
ENSDART00000057641
tetraspanin 15
chr6_+_30533504 0.05 ENSDART00000155842
WWC family member 3
chr2_+_2223837 0.05 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr12_+_38770654 0.05 ENSDART00000155367
kinesin family member 19
chr7_+_53755054 0.04 ENSDART00000181629
neogenin 1a
chr7_-_35126374 0.04 ENSDART00000141211
hydroxysteroid (11-beta) dehydrogenase 2
chr7_-_40959667 0.04 ENSDART00000084070
RNA binding motif protein 33a
chr19_-_27830818 0.04 ENSDART00000131767
PAP associated domain containing 7
chr1_-_46984142 0.04 ENSDART00000125032
pbx/knotted 1 homeobox 1.2
chr5_+_63767376 0.04 ENSDART00000138898
regulator of G protein signaling 3b
chr16_-_35952789 0.04 ENSDART00000180118
eva-1 homolog Ba (C. elegans)
chr5_-_201600 0.03 ENSDART00000158495

chr2_-_9259283 0.03 ENSDART00000133092
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5a
chr15_-_30450898 0.03 ENSDART00000156584
musashi RNA-binding protein 2b
chr16_-_31451720 0.03 ENSDART00000146886
casein kinase 2, alpha 1 polypeptide
chr11_+_29671661 0.03 ENSDART00000024318
ENSDART00000165024
ring finger protein 207a
chr16_-_31451282 0.03 ENSDART00000192354
casein kinase 2, alpha 1 polypeptide
chr10_-_33156789 0.03 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cut-like homeobox 1a
chr6_-_53144336 0.02 ENSDART00000154429
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr17_+_10501647 0.02 ENSDART00000140391
TYRO3 protein tyrosine kinase
chr2_+_25378457 0.02 ENSDART00000089108
fibronectin type III domain containing 3Ba
chr9_-_3934963 0.02 ENSDART00000062336
ubiquitin protein ligase E3 component n-recognin 3
chr1_-_27014872 0.02 ENSDART00000147414
ENSDART00000134032
ENSDART00000192087
ENSDART00000189111
ENSDART00000187348
ENSDART00000187248
centlein, centrosomal protein
chr5_+_19094153 0.02 ENSDART00000186525
ENSDART00000064752
unc-13 homolog Ba (C. elegans)
chr17_-_8570257 0.02 ENSDART00000154713
ENSDART00000121488
frizzled class receptor 3b
chr21_+_22878834 0.02 ENSDART00000065562
PCF11 cleavage and polyadenylation factor subunit
chr8_+_18588551 0.02 ENSDART00000177476
ENSDART00000063539
proline rich Gla (G-carboxyglutamic acid) 1
chr11_+_13528437 0.02 ENSDART00000011362
arrestin domain containing 2
chr4_-_5366566 0.01 ENSDART00000150788
si:dkey-14d8.1
chr13_+_8604710 0.01 ENSDART00000091097
suppressor of cytokine signaling 5b
chr5_+_19094462 0.01 ENSDART00000190596
unc-13 homolog Ba (C. elegans)
chr8_-_22514918 0.01 ENSDART00000021514
ENSDART00000189272
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr12_+_18458502 0.01 ENSDART00000108745
ring finger protein 151
chr4_-_9909371 0.01 ENSDART00000102656
si:dkey-22l11.6
chr6_+_45347219 0.01 ENSDART00000188240

chr23_+_5490854 0.00 ENSDART00000175403
tubby like protein 1a
chr7_+_42460302 0.00 ENSDART00000004120
ADAM metallopeptidase with thrombospondin type 1 motif, 18

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb8a+hoxb8b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.8 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 0.5 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.3 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.3 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.3 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.3 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.8 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.3 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.7 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.4 GO:0031579 membrane raft organization(GO:0031579)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0 0.5 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.1 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.2 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.2 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.1 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:1900186 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0016586 RSC complex(GO:0016586)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.5 GO:0016208 AMP binding(GO:0016208)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac