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PRJNA207719: Tissue specific transcriptome profiling

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Results for ikzf1

Z-value: 1.43

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Transcription factors associated with ikzf1

Gene Symbol Gene ID Gene Info
ikzf1
ENSDARG00000013539 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ikzf1dr11_v1_chr13_-_15994419_159944720.276.6e-01Click!

Activity profile of ikzf1 motif

Sorted Z-values of ikzf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_29161609 1.03 ENSDART00000180752
pkmb
pyruvate kinase M1/2b
chr5_-_71722257 0.97 ENSDART00000013404
ak1
adenylate kinase 1
chr5_+_32222303 0.77 ENSDART00000051362
myhc4
myosin heavy chain 4
chr3_-_32817274 0.76 ENSDART00000142582
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr23_-_23256726 0.72 ENSDART00000131353
si:dkey-98j1.5
si:dkey-98j1.5
chr8_-_18535822 0.68 ENSDART00000100558
nexn
nexilin (F actin binding protein)
chr6_-_39764995 0.65 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr13_-_2189761 0.63 ENSDART00000166255
mlip
muscular LMNA-interacting protein
chr6_-_29195642 0.62 ENSDART00000078625
dpt
dermatopontin
chr7_+_39386982 0.61 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr25_-_31396479 0.58 ENSDART00000156828
prr33
proline rich 33
chr2_-_15324837 0.53 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr22_-_282498 0.45 ENSDART00000182766
CABZ01079178.1

chr22_-_29191152 0.44 ENSDART00000132702
pvalb7
parvalbumin 7
chr23_+_6077503 0.43 ENSDART00000081714
ENSDART00000139834
mybpha
myosin binding protein Ha
chr22_-_237651 0.43 ENSDART00000075210
zgc:66156
zgc:66156
chr7_-_38792543 0.43 ENSDART00000157416
si:dkey-23n7.10
si:dkey-23n7.10
chr10_-_26163989 0.41 ENSDART00000136472
trim3b
tripartite motif containing 3b
chr7_-_58098814 0.40 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr19_+_22216778 0.39 ENSDART00000052521
nfatc1
nuclear factor of activated T cells 1
chr13_-_22699024 0.38 ENSDART00000016946
glud1a
glutamate dehydrogenase 1a
chr8_+_1009831 0.37 ENSDART00000172414
fabp1b.2
fatty acid binding protein 1b, liver, tandem duplicate 2
chr17_-_14671098 0.36 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr21_-_131236 0.35 ENSDART00000160005
si:ch1073-398f15.1
si:ch1073-398f15.1
chr2_+_55665322 0.35 ENSDART00000183636
ENSDART00000183814
klf2b
Kruppel-like factor 2b
chr2_+_55665095 0.34 ENSDART00000059188
klf2b
Kruppel-like factor 2b
chr9_-_21067971 0.34 ENSDART00000004333
tbx15
T-box 15
chr1_-_59116617 0.34 ENSDART00000137471
ENSDART00000140490
MFAP4 (1 of many)
si:zfos-2330d3.7
chr7_-_35432901 0.34 ENSDART00000026712
mmp2
matrix metallopeptidase 2
chr5_-_57641257 0.34 ENSDART00000149282
hspb2
heat shock protein, alpha-crystallin-related, b2
chr2_-_21335131 0.33 ENSDART00000057022
klhl40a
kelch-like family member 40a
chr17_+_10242166 0.33 ENSDART00000170420
clec14a
C-type lectin domain containing 14A
chr12_+_17100021 0.32 ENSDART00000177923
acta2
actin, alpha 2, smooth muscle, aorta
chr18_-_16792561 0.32 ENSDART00000145546
ampd3b
adenosine monophosphate deaminase 3b
chr17_+_996509 0.32 ENSDART00000158830
cyp1c2
cytochrome P450, family 1, subfamily C, polypeptide 2
chr2_+_25278107 0.31 ENSDART00000131977
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr13_-_24825691 0.31 ENSDART00000142745
slka
STE20-like kinase a
chr11_+_10541258 0.31 ENSDART00000132365
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr13_-_13754091 0.31 ENSDART00000131255
ky
kyphoscoliosis peptidase
chr11_-_27953135 0.30 ENSDART00000168338
ece1
endothelin converting enzyme 1
chr9_-_44642108 0.30 ENSDART00000086202
pde1a
phosphodiesterase 1A, calmodulin-dependent
chr18_+_20494413 0.30 ENSDART00000060295
rapsn
receptor-associated protein of the synapse, 43kD
chr7_-_24390879 0.30 ENSDART00000036680
ptgr1
prostaglandin reductase 1
chr3_-_59981476 0.29 ENSDART00000035878
ENSDART00000124038
cdr2l
cerebellar degeneration-related protein 2-like
chr3_-_59981162 0.28 ENSDART00000128790
cdr2l
cerebellar degeneration-related protein 2-like
chr13_-_36391496 0.28 ENSDART00000100217
ENSDART00000140243
actn1
actinin, alpha 1
chr17_-_43517542 0.28 ENSDART00000133665
mrpl35
mitochondrial ribosomal protein L35
chr15_-_23376541 0.27 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr5_+_37517800 0.27 ENSDART00000048107
FP102018.1
Danio rerio latent transforming growth factor beta binding protein 3 (ltbp3), mRNA.
chr1_-_10914523 0.27 ENSDART00000007013
dmd
dystrophin
chr4_-_4119396 0.27 ENSDART00000067409
ENSDART00000138221
lmod2b
leiomodin 2 (cardiac) b
chr7_+_31879649 0.27 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr9_-_34260214 0.26 ENSDART00000012385
me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr20_+_20637866 0.26 ENSDART00000060203
ENSDART00000079079
rtn1b
reticulon 1b
chr25_+_18563476 0.26 ENSDART00000170841
cav1
caveolin 1
chr2_-_689047 0.26 ENSDART00000122732
foxc1a
forkhead box C1a
chr12_+_20641102 0.26 ENSDART00000152964
calcoco2
calcium binding and coiled-coil domain 2
chr19_-_42462491 0.26 ENSDART00000131715
psmb4
proteasome subunit beta 4
chr17_+_25444323 0.25 ENSDART00000030691
clic4
chloride intracellular channel 4
chr9_-_29985390 0.25 ENSDART00000134157
il1rapl1a
interleukin 1 receptor accessory protein-like 1a
chr12_-_26415499 0.25 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr24_-_35699595 0.25 ENSDART00000167990
mapre2
microtubule-associated protein, RP/EB family, member 2
chr19_+_12583577 0.25 ENSDART00000151508
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr24_-_35699444 0.24 ENSDART00000166567
mapre2
microtubule-associated protein, RP/EB family, member 2
chr12_-_26430507 0.24 ENSDART00000153214
synpo2lb
synaptopodin 2-like b
chr7_-_24472991 0.24 ENSDART00000121684
nat8l
N-acetyltransferase 8-like
chr2_+_42724404 0.24 ENSDART00000075392
basp1
brain abundant, membrane attached signal protein 1
chr9_-_21067673 0.24 ENSDART00000180257
tbx15
T-box 15
chr21_-_25741096 0.23 ENSDART00000181756
cldnh
claudin h
chr20_+_54738210 0.23 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr13_+_24842857 0.23 ENSDART00000123866
dusp13a
dual specificity phosphatase 13a
chr1_+_1838164 0.23 ENSDART00000006013
atp1a1a.5
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 5
chr15_-_33933790 0.22 ENSDART00000165162
ENSDART00000182258
ENSDART00000183240
mag
myelin associated glycoprotein
chr19_-_40199081 0.22 ENSDART00000051970
ENSDART00000151079
grn2
granulin 2
chr13_+_52061034 0.22 ENSDART00000170383
CABZ01089777.1

chr10_-_44008241 0.21 ENSDART00000137686
acads
acyl-CoA dehydrogenase short chain
chr23_-_26077038 0.21 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr18_-_41375120 0.21 ENSDART00000098673
ptx3a
pentraxin 3, long a
chr20_+_15982482 0.21 ENSDART00000020999
angptl1a
angiopoietin-like 1a
chr19_-_38539670 0.21 ENSDART00000136775
col16a1
collagen, type XVI, alpha 1
chr21_-_35534401 0.21 ENSDART00000112308
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr4_-_12914163 0.21 ENSDART00000140002
ENSDART00000145917
ENSDART00000141355
ENSDART00000067135
msrb3
methionine sulfoxide reductase B3
chr15_-_33904831 0.21 ENSDART00000164333
ENSDART00000165404
mag
myelin associated glycoprotein
chr1_+_51496862 0.21 ENSDART00000150433
meis1a
Meis homeobox 1 a
chr3_+_41922114 0.21 ENSDART00000138280
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_-_9648542 0.20 ENSDART00000172628
clcn1a
chloride channel, voltage-sensitive 1a
chr7_+_17816470 0.20 ENSDART00000173807
eml3
echinoderm microtubule associated protein like 3
chr10_-_8358396 0.20 ENSDART00000059322
csgalnact1a
chondroitin sulfate N-acetylgalactosaminyltransferase 1a
chr7_+_39410180 0.20 ENSDART00000168641
CT030188.1

chr1_+_5275811 0.20 ENSDART00000189676
spry2
sprouty RTK signaling antagonist 2
chr22_+_15898221 0.20 ENSDART00000062587
klf2a
Kruppel-like factor 2a
chr17_-_33416020 0.20 ENSDART00000140149
ccdc28a
coiled-coil domain containing 28A
chr17_+_6793001 0.20 ENSDART00000030773
foxo3a
forkhead box O3A
chr5_-_31712399 0.19 ENSDART00000141328
pip5kl1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr2_+_58377395 0.19 ENSDART00000193511
vapal
VAMP (vesicle-associated membrane protein)-associated protein A, like
chr12_+_23762966 0.19 ENSDART00000152942
ENSDART00000181725
jcada
junctional cadherin 5 associated a
chr23_+_34047413 0.19 ENSDART00000143933
ENSDART00000123925
ENSDART00000176139
chchd6a
coiled-coil-helix-coiled-coil-helix domain containing 6a
chr17_-_8899323 0.19 ENSDART00000081590
nkl.1
NK-lysin tandem duplicate 1
chr17_+_2549503 0.19 ENSDART00000156843
si:dkey-248g15.3
si:dkey-248g15.3
chr1_+_26099250 0.19 ENSDART00000054205
ndufb6
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6
chr13_-_36525982 0.19 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr20_+_20638034 0.19 ENSDART00000189759
rtn1b
reticulon 1b
chr5_-_31716713 0.19 ENSDART00000131443
dpm2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr15_-_33925851 0.18 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr5_+_24287927 0.18 ENSDART00000143563
zdhhc23a
zinc finger, DHHC-type containing 23a
chr15_-_47193564 0.18 ENSDART00000172453
LSAMP
limbic system-associated membrane protein
chr17_-_45370200 0.18 ENSDART00000186208
znf106a
zinc finger protein 106a
chr10_-_8129175 0.18 ENSDART00000133921
ndufa9b
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9b
chr14_-_51855047 0.18 ENSDART00000088912
cplx1
complexin 1
chr3_-_7134113 0.18 ENSDART00000180849
BX005085.6

chr24_-_28259127 0.17 ENSDART00000149589
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr20_+_2039518 0.17 ENSDART00000043157
CABZ01088134.1

chr23_+_43668756 0.17 ENSDART00000112598
otud4
OTU deubiquitinase 4
chr3_-_52614747 0.17 ENSDART00000154365
trim35-13
tripartite motif containing 35-13
chr5_-_26466169 0.17 ENSDART00000144035
arvcfb
ARVCF, delta catenin family member b
chr2_-_34555945 0.17 ENSDART00000056671
brinp2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr5_+_32817688 0.17 ENSDART00000139472
crata
carnitine O-acetyltransferase a
chr11_+_6456146 0.17 ENSDART00000036939
gadd45ba
growth arrest and DNA-damage-inducible, beta a
chr23_+_9057999 0.16 ENSDART00000091899
ccm2l
cerebral cavernous malformation 2-like
chr24_-_38816725 0.16 ENSDART00000063231
nog2
noggin 2
chr2_-_32501501 0.16 ENSDART00000181309
faim2a
Fas apoptotic inhibitory molecule 2a
chr20_-_27330383 0.16 ENSDART00000153277
asb2a.1
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr12_-_47782623 0.16 ENSDART00000115742
selenou1b
selenoprotein U1b
chr2_+_35993404 0.16 ENSDART00000170845
lamc2
laminin, gamma 2
chr12_+_30109698 0.15 ENSDART00000042572
ENSDART00000153025
ablim1b
actin binding LIM protein 1b
chr10_+_9697097 0.15 ENSDART00000167821
rabgap1
RAB GTPase activating protein 1
chr23_-_3674443 0.15 ENSDART00000134830
ENSDART00000057422
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr14_+_7048930 0.15 ENSDART00000109138
hbegfa
heparin-binding EGF-like growth factor a
chr5_+_19337108 0.15 ENSDART00000089078
acacb
acetyl-CoA carboxylase beta
chr14_+_16813816 0.15 ENSDART00000161201
limch1b
LIM and calponin homology domains 1b
chr3_+_59411956 0.15 ENSDART00000166982
sec14l1
SEC14-like lipid binding 1
chr15_+_15779184 0.15 ENSDART00000156902
si:ch211-33e4.2
si:ch211-33e4.2
chr17_+_33415542 0.14 ENSDART00000183169
snap23.1
synaptosomal-associated protein 23.1
chr19_-_7291733 0.14 ENSDART00000015559
sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr10_+_31951338 0.14 ENSDART00000019416
lhfpl6
LHFPL tetraspan subfamily member 6
chr22_-_26834043 0.14 ENSDART00000087202
si:dkey-44g23.5
si:dkey-44g23.5
chr7_+_39410393 0.14 ENSDART00000158561
ENSDART00000185173
CT030188.1

chr19_-_9829965 0.14 ENSDART00000136842
ENSDART00000142766
cacng8a
calcium channel, voltage-dependent, gamma subunit 8a
chr21_+_7582036 0.14 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr2_+_3428357 0.14 ENSDART00000125967
CU633991.1

chr4_+_2619132 0.14 ENSDART00000128807
gpr22a
G protein-coupled receptor 22a
chr3_+_32443395 0.14 ENSDART00000188447
prr12b
proline rich 12b
chr5_-_28606916 0.14 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr12_+_23991276 0.13 ENSDART00000153136
psme4b
proteasome activator subunit 4b
chr22_-_34551568 0.13 ENSDART00000148147
rnf123
ring finger protein 123
chr5_-_26181863 0.13 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr19_+_24872159 0.13 ENSDART00000158490
si:ch211-195b13.1
si:ch211-195b13.1
chr22_-_4742866 0.13 ENSDART00000177992
CR751224.1

chr2_-_42558549 0.13 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr14_-_3268155 0.13 ENSDART00000177244
pdgfrb
platelet-derived growth factor receptor, beta polypeptide
chr3_-_58189429 0.13 ENSDART00000156092
si:ch211-256e16.11
si:ch211-256e16.11
chr7_+_17816006 0.13 ENSDART00000080834
eml3
echinoderm microtubule associated protein like 3
chr15_-_2640966 0.13 ENSDART00000063320
cldne
claudin e
chr17_+_24747209 0.13 ENSDART00000154623
stac
SH3 and cysteine rich domain
chr2_-_14571577 0.13 ENSDART00000170687
pde4bb
phosphodiesterase 4B, cAMP-specific b
chr8_-_51579286 0.13 ENSDART00000147878
ankrd39
ankyrin repeat domain 39
chr17_+_25414033 0.13 ENSDART00000001691
tdh2
L-threonine dehydrogenase 2
chr5_+_23598364 0.13 ENSDART00000132155
kat5b
K(lysine) acetyltransferase 5b
chr9_+_33145522 0.13 ENSDART00000005879
atp5po
ATP synthase peripheral stalk subunit OSCP
chr17_+_8925232 0.13 ENSDART00000036668
psmc1a
proteasome 26S subunit, ATPase 1a
chr7_+_31130667 0.12 ENSDART00000173937
tjp1a
tight junction protein 1a
chr9_+_2507526 0.12 ENSDART00000166579
wipf1a
WAS/WASL interacting protein family, member 1a
chr21_+_13182149 0.12 ENSDART00000140267
sptan1
spectrin alpha, non-erythrocytic 1
chr23_+_21663631 0.12 ENSDART00000066125
dhrs3a
dehydrogenase/reductase (SDR family) member 3a
chr7_+_25003313 0.12 ENSDART00000131935
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr21_-_40835069 0.12 ENSDART00000004686
limk1b
LIM domain kinase 1b
chr13_-_8229977 0.12 ENSDART00000139728
si:ch211-250c4.4
si:ch211-250c4.4
chr2_-_32505091 0.12 ENSDART00000141884
ENSDART00000056639
faim2a
Fas apoptotic inhibitory molecule 2a
chr7_+_72279584 0.12 ENSDART00000172021
tollip
toll interacting protein
chr16_-_8927425 0.12 ENSDART00000000382
triob
trio Rho guanine nucleotide exchange factor b
chr12_+_17042754 0.12 ENSDART00000066439
ch25h
cholesterol 25-hydroxylase
chr16_+_37470717 0.12 ENSDART00000112003
ENSDART00000188431
ENSDART00000192837
adgrb1a
adhesion G protein-coupled receptor B1a
chr2_-_21847935 0.12 ENSDART00000003940
rab2a
RAB2A, member RAS oncogene family
chr6_-_54107269 0.12 ENSDART00000190017
hyal2a
hyaluronoglucosaminidase 2a
chr24_+_35947077 0.12 ENSDART00000173406
obscnb
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr18_+_20869923 0.12 ENSDART00000138471
pgpep1l
pyroglutamyl-peptidase I-like
chr8_+_30671060 0.11 ENSDART00000193749
adora2aa
adenosine A2a receptor a
chr3_+_27665160 0.11 ENSDART00000103660
clcn7
chloride channel 7
chr2_-_31936966 0.11 ENSDART00000169484
ENSDART00000192492
ENSDART00000027689
amph
amphiphysin
chr21_+_6290566 0.11 ENSDART00000161647
fnbp1b
formin binding protein 1b
chr23_+_2361184 0.11 ENSDART00000184469
CABZ01048666.1

chr19_+_33732487 0.11 ENSDART00000010294
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_+_28735151 0.11 ENSDART00000150376
ldb1a
LIM domain binding 1a
chr3_-_21288202 0.11 ENSDART00000191766
ENSDART00000187319
fam171a2a
family with sequence similarity 171, member A2a
chr25_-_31763897 0.11 ENSDART00000041740
ubl7a
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr16_+_1353894 0.11 ENSDART00000148426
celf3b
cugbp, Elav-like family member 3b
chr10_+_31953502 0.11 ENSDART00000185634
lhfpl6
LHFPL tetraspan subfamily member 6
chr25_-_20238793 0.11 ENSDART00000145987
dnm1l
dynamin 1-like
chr9_+_55857193 0.11 ENSDART00000160980
sept10
septin 10
chr15_+_16908085 0.11 ENSDART00000186870
ypel2b
yippee-like 2b
chr12_-_7824291 0.11 ENSDART00000148673
ENSDART00000149453
ank3b
ankyrin 3b
chr25_-_23526058 0.11 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr1_+_36194761 0.11 ENSDART00000053773
ENSDART00000147458
lsm6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr7_-_45076131 0.11 ENSDART00000110590
zgc:194678
zgc:194678
chr10_+_21786656 0.11 ENSDART00000185851
ENSDART00000167219
pcdh1g26
protocadherin 1 gamma 26
chr23_-_20002459 0.11 ENSDART00000163396
b4galt3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr14_+_23158021 0.11 ENSDART00000084664
enox2
ecto-NOX disulfide-thiol exchanger 2
chr20_-_26421112 0.11 ENSDART00000183767
ENSDART00000182330
akap12b
A kinase (PRKA) anchor protein 12b
chr13_-_46991577 0.11 ENSDART00000114748
vip
vasoactive intestinal peptide
chr3_+_40170216 0.11 ENSDART00000011568
syngr3a
synaptogyrin 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of ikzf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.1 1.0 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.3 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.3 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.1 0.2 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 0.7 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.5 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.4 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.3 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.1 0.3 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.2 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.0 0.2 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.3 GO:0055016 hypochord development(GO:0055016)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.1 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:0033605 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.7 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.2 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.2 GO:1904035 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.0 0.1 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0035176 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.1 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.3 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0048713 positive regulation of glial cell differentiation(GO:0045687) regulation of oligodendrocyte differentiation(GO:0048713) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.2 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.0 GO:0042040 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0044819 mitotic G1/S transition checkpoint(GO:0044819)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 1.8 GO:0031674 I band(GO:0031674)
0.0 1.3 GO:0042383 sarcolemma(GO:0042383)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.9 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.4 GO:0030017 sarcomere(GO:0030017)
0.0 0.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.3 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.1 0.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.7 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.1 0.2 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.6 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.4 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis