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PRJNA207719: Tissue specific transcriptome profiling

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Results for ikzf2

Z-value: 1.27

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Transcription factors associated with ikzf2

Gene Symbol Gene ID Gene Info
ikzf2
ENSDARG00000069111 IKAROS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IKZF2dr11_v1_chr9_-_40014339_400143390.177.8e-01Click!

Activity profile of ikzf2 motif

Sorted Z-values of ikzf2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_1689775 0.88 ENSDART00000048828
atp1a1a.4
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 4
chr7_+_39386982 0.82 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr20_+_46040666 0.82 ENSDART00000060744
si:dkey-7c18.24
si:dkey-7c18.24
chr13_+_22264914 0.79 ENSDART00000060576
myoz1a
myozenin 1a
chr3_-_61181018 0.71 ENSDART00000187970
pvalb4
parvalbumin 4
chr16_+_25245857 0.68 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr13_-_31647323 0.66 ENSDART00000135381
six4a
SIX homeobox 4a
chr16_+_23398369 0.66 ENSDART00000037694
s100a10b
S100 calcium binding protein A10b
chr16_+_23397785 0.65 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr3_+_30921246 0.62 ENSDART00000076850
cldni
claudin i
chr23_-_32162810 0.60 ENSDART00000155905
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr9_-_22831836 0.57 ENSDART00000142585
neb
nebulin
chr3_-_61203203 0.55 ENSDART00000171787
pvalb1
parvalbumin 1
chr11_+_10548171 0.53 ENSDART00000191497
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr4_+_7508316 0.50 ENSDART00000170924
ENSDART00000170933
ENSDART00000164985
ENSDART00000167571
ENSDART00000158843
ENSDART00000158999
tnnt2e
troponin T2e, cardiac
chr5_-_38820046 0.50 ENSDART00000182886
cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr18_+_5543677 0.49 ENSDART00000146161
ENSDART00000136189
nnt2
nicotinamide nucleotide transhydrogenase 2
chr6_-_46742455 0.46 ENSDART00000011970
zgc:66479
zgc:66479
chr21_+_5800306 0.46 ENSDART00000020603
ccng2
cyclin G2
chr12_+_14084291 0.43 ENSDART00000189734
si:ch211-217a12.1
si:ch211-217a12.1
chr25_-_18470695 0.42 ENSDART00000034377
cpa5
carboxypeptidase A5
chr8_-_23599096 0.41 ENSDART00000183096
slc38a5b
solute carrier family 38, member 5b
chr10_-_7785930 0.41 ENSDART00000043961
ENSDART00000111058
mpx
myeloid-specific peroxidase
chr18_+_5273953 0.40 ENSDART00000165073
slc12a1
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr16_+_26774182 0.40 ENSDART00000042895
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr18_-_16123222 0.39 ENSDART00000061189
sspn
sarcospan (Kras oncogene-associated gene)
chr2_+_45191049 0.39 ENSDART00000165392
ccl20a.3
chemokine (C-C motif) ligand 20a, duplicate 3
chr19_-_32804535 0.38 ENSDART00000175613
ENSDART00000052098
nt5c1aa
5'-nucleotidase, cytosolic IAa
chr3_+_23691847 0.37 ENSDART00000078453
hoxb7a
homeobox B7a
chr23_+_36101185 0.37 ENSDART00000103139
hoxc8a
homeobox C8a
chr12_-_4070058 0.37 ENSDART00000042200
aldoab
aldolase a, fructose-bisphosphate, b
chr3_+_14611299 0.37 ENSDART00000140577
tspan35
tetraspanin 35
chr24_+_34085940 0.36 ENSDART00000171189
asb10
ankyrin repeat and SOCS box containing 10
chr11_+_34235372 0.36 ENSDART00000063150
fam43a
family with sequence similarity 43, member A
chr23_+_36087219 0.35 ENSDART00000154825
hoxc3a
homeobox C3a
chr23_+_20408227 0.35 ENSDART00000134727
si:rp71-17i16.4
si:rp71-17i16.4
chr1_-_59169815 0.35 ENSDART00000100163
wu:fk65c09
wu:fk65c09
chr3_-_20091964 0.35 ENSDART00000029386
ENSDART00000020253
ENSDART00000124326
slc4a1a
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr4_+_76659013 0.34 ENSDART00000147908
ENSDART00000134229
ms4a17a.5
membrane-spanning 4-domains, subfamily A, member 17A.5
chr19_-_25519612 0.33 ENSDART00000133150
C1GALT1 (1 of many)
si:dkey-202e17.1
chr18_+_26750516 0.33 ENSDART00000110843
alpk3a
alpha-kinase 3a
chr16_-_31976269 0.32 ENSDART00000139664
styk1
serine/threonine/tyrosine kinase 1
chr15_-_37829160 0.32 ENSDART00000099425
ctrl
chymotrypsin-like
chr18_+_7591381 0.32 ENSDART00000136313
si:dkeyp-1h4.6
si:dkeyp-1h4.6
chr5_-_68916623 0.30 ENSDART00000141917
ENSDART00000109053
ank1a
ankyrin 1, erythrocytic a
chr7_-_35432901 0.30 ENSDART00000026712
mmp2
matrix metallopeptidase 2
chr5_-_68916455 0.30 ENSDART00000171465
ank1a
ankyrin 1, erythrocytic a
chr5_+_43783360 0.29 ENSDART00000019431
nos2a
nitric oxide synthase 2a, inducible
chr16_-_31756859 0.28 ENSDART00000149170
ENSDART00000126617
ENSDART00000182722
ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr7_+_46003449 0.28 ENSDART00000159700
ENSDART00000173625
si:ch211-260e23.9
si:ch211-260e23.9
chr10_+_36662640 0.28 ENSDART00000063359
ucp2
uncoupling protein 2
chr4_+_18843015 0.27 ENSDART00000152086
ENSDART00000066977
ENSDART00000132567
bik
BCL2 interacting killer
chr1_+_35494837 0.27 ENSDART00000140724
gab1
GRB2-associated binding protein 1
chr7_+_2455344 0.26 ENSDART00000172942
si:dkey-125e8.4
si:dkey-125e8.4
chr23_+_45027263 0.26 ENSDART00000058364
hmgb2b
high mobility group box 2b
chr13_-_22699024 0.26 ENSDART00000016946
glud1a
glutamate dehydrogenase 1a
chr24_+_25919809 0.25 ENSDART00000006615
map3k15
mitogen-activated protein kinase kinase kinase 15
chr25_-_8602437 0.25 ENSDART00000171200
rhcgb
Rh family, C glycoprotein b
chr21_-_11655010 0.25 ENSDART00000144370
ENSDART00000139814
ENSDART00000139289
cast
calpastatin
chr8_-_21372446 0.25 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr25_-_13408760 0.24 ENSDART00000154445
gins3
GINS complex subunit 3
chr14_-_6666854 0.24 ENSDART00000133031
si:dkeyp-44a8.4
si:dkeyp-44a8.4
chr1_-_55068941 0.24 ENSDART00000152143
ENSDART00000152590
peli1a
pellino E3 ubiquitin protein ligase 1a
chr13_+_16279890 0.24 ENSDART00000101775
ENSDART00000057948
anxa11a
annexin A11a
chr12_-_48477031 0.24 ENSDART00000105176
ndufb8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr19_+_46158078 0.24 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr22_-_17653143 0.24 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr8_-_31062811 0.23 ENSDART00000142528
slc20a1a
solute carrier family 20, member 1a
chr6_+_39360377 0.23 ENSDART00000028260
ENSDART00000151322
zgc:77517
zgc:77517
chr4_+_76775837 0.23 ENSDART00000174167
ms4a17a.10
membrane-spanning 4-domains, subfamily A, member 17A.10
chr2_-_24022085 0.22 ENSDART00000088643
ENSDART00000189822
col15a1b
collagen, type XV, alpha 1b
chr12_+_22576404 0.22 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr9_+_5862040 0.22 ENSDART00000129117
pdzk1
PDZ domain containing 1
chr16_+_29492749 0.22 ENSDART00000179680
ctsk
cathepsin K
chr7_+_73822054 0.21 ENSDART00000109720
zgc:163061
zgc:163061
chr21_+_25187210 0.21 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
si:dkey-183i3.5
chr1_-_35695614 0.21 ENSDART00000133813
ENSDART00000145291
ENSDART00000176451
si:dkey-27h10.2
si:dkey-27h10.2
chr18_+_19648275 0.21 ENSDART00000100569
smad6b
SMAD family member 6b
chr5_+_8492640 0.21 ENSDART00000171701
osmr
oncostatin M receptor
chr3_+_39540014 0.20 ENSDART00000074848
zgc:165423
zgc:165423
chr2_+_55984788 0.20 ENSDART00000183599
nmrk2
nicotinamide riboside kinase 2
chr4_+_25220674 0.20 ENSDART00000066934
itih5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr6_+_49021703 0.20 ENSDART00000149394
slc16a1a
solute carrier family 16 (monocarboxylate transporter), member 1a
chr20_+_38910214 0.20 ENSDART00000047362
msra
methionine sulfoxide reductase A
chr7_+_19482084 0.20 ENSDART00000173873
si:ch211-212k18.7
si:ch211-212k18.7
chr16_+_13427967 0.20 ENSDART00000038196
zgc:101640
zgc:101640
chr14_-_46198373 0.20 ENSDART00000031640
ENSDART00000132966
zgc:113425
zgc:113425
chr11_-_21404358 0.19 ENSDART00000129062
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr9_+_563547 0.19 ENSDART00000162761
CU984600.2

chr20_+_16881883 0.19 ENSDART00000130107
nfkbiaa
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr6_-_21534301 0.19 ENSDART00000126186
psmd12
proteasome 26S subunit, non-ATPase 12
chr14_-_14566417 0.19 ENSDART00000159056
si:dkey-27i16.2
si:dkey-27i16.2
chr17_-_28749640 0.19 ENSDART00000000948
coch
coagulation factor C homolog, cochlin (Limulus polyphemus)
chr14_-_1280907 0.19 ENSDART00000186150
CABZ01081490.1

chr3_+_23692462 0.18 ENSDART00000145934
hoxb7a
homeobox B7a
chr12_+_38878830 0.18 ENSDART00000156926
si:ch211-39f2.3
si:ch211-39f2.3
chr18_-_7481036 0.18 ENSDART00000101292
si:dkey-238c7.16
si:dkey-238c7.16
chr18_+_26422124 0.18 ENSDART00000060245
ctsh
cathepsin H
chr13_-_37620091 0.18 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
zgc:152791
chr9_+_14010823 0.18 ENSDART00000143837
si:ch211-67e16.3
si:ch211-67e16.3
chr16_+_25126935 0.18 ENSDART00000058945
zgc:92590
zgc:92590
chr19_+_823945 0.18 ENSDART00000142287
ppp1r18
protein phosphatase 1, regulatory subunit 18
chr1_+_9966384 0.18 ENSDART00000132607
si:dkeyp-75b4.8
si:dkeyp-75b4.8
chr3_-_34528306 0.17 ENSDART00000023039
sept9a
septin 9a
chr15_+_46356879 0.17 ENSDART00000154388
wu:fb18f06
wu:fb18f06
chr9_+_45839260 0.17 ENSDART00000114814
twist2
twist2
chr11_+_20899029 0.17 ENSDART00000163029
zgc:162182
zgc:162182
chr20_+_1960092 0.17 ENSDART00000191892
CABZ01103860.1

chr19_+_11217279 0.17 ENSDART00000181859
si:ch73-109i22.2
si:ch73-109i22.2
chr21_+_5560040 0.17 ENSDART00000163205
si:ch211-134a4.6
si:ch211-134a4.6
chr21_+_11248448 0.17 ENSDART00000142431
arid6
AT-rich interaction domain 6
chr2_-_45191319 0.17 ENSDART00000192272
CR407590.2

chr18_+_44703343 0.16 ENSDART00000131510
b3gnt2l
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, like
chr13_-_349952 0.16 ENSDART00000133731
ENSDART00000140326
ENSDART00000189389
ENSDART00000185865
ENSDART00000109634
ENSDART00000147058
ENSDART00000142695
si:ch1073-291c23.2
si:ch1073-291c23.2
chr16_+_38201840 0.16 ENSDART00000044971
myo1eb
myosin IE, b
chr1_+_35495368 0.16 ENSDART00000053806
gab1
GRB2-associated binding protein 1
chr21_-_13051613 0.16 ENSDART00000190777
myorg
myogenesis regulating glycosidase (putative)
chr12_+_17106117 0.16 ENSDART00000149990
acta2
actin, alpha 2, smooth muscle, aorta
chr21_+_11385031 0.15 ENSDART00000040598
cel.2
carboxyl ester lipase, tandem duplicate 2
chr16_-_26140768 0.15 ENSDART00000143960
cd79a
CD79a molecule, immunoglobulin-associated alpha
chr6_+_19950107 0.15 ENSDART00000181632
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr24_-_15263142 0.15 ENSDART00000183176
ENSDART00000006930
rttn
rotatin
chr17_-_11439815 0.15 ENSDART00000130105
psma3
proteasome subunit alpha 3
chr6_-_48347498 0.15 ENSDART00000149159
capza1a
capping protein (actin filament) muscle Z-line, alpha 1a
chr20_+_26702377 0.15 ENSDART00000077753
foxc1b
forkhead box C1b
chr25_-_13320986 0.15 ENSDART00000169238
si:ch211-194m7.8
si:ch211-194m7.8
chr5_+_61361815 0.15 ENSDART00000009507
gatsl2
GATS protein-like 2
chr1_-_52497834 0.15 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr14_-_1355544 0.15 ENSDART00000060417
cetn4
centrin 4
chr11_-_13126505 0.15 ENSDART00000158377
elovl1b
ELOVL fatty acid elongase 1b
chr2_-_37210397 0.15 ENSDART00000084938
apoda.1
apolipoprotein Da, duplicate 1
chr3_-_32957702 0.15 ENSDART00000146586
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr12_+_38929663 0.14 ENSDART00000156334
si:dkey-239b22.1
si:dkey-239b22.1
chr20_+_38276690 0.14 ENSDART00000061437
ccl38.6
chemokine (C-C motif) ligand 38, duplicate 6
chr12_+_10163585 0.14 ENSDART00000106191
psmc5
proteasome 26S subunit, ATPase 5
chr13_-_4223955 0.14 ENSDART00000113060
dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr15_-_951118 0.14 ENSDART00000171427
alox5b.1
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr2_-_31791633 0.14 ENSDART00000180662
retreg1
reticulophagy regulator 1
chr16_+_7991274 0.14 ENSDART00000179704
ano10a
anoctamin 10a
chr16_-_38333976 0.14 ENSDART00000031895
cdc42se1
CDC42 small effector 1
chr23_+_36106790 0.14 ENSDART00000128533
hoxc3a
homeobox C3a
chr10_+_9159279 0.14 ENSDART00000064968
rasgef1bb
RasGEF domain family, member 1Bb
chr2_-_58183499 0.14 ENSDART00000172281
ENSDART00000186262
si:ch1073-185p12.2
si:ch1073-185p12.2
chr20_-_44090624 0.14 ENSDART00000048978
ENSDART00000082283
ENSDART00000082276
runx2b
runt-related transcription factor 2b
chr11_+_18216404 0.14 ENSDART00000086437
tmcc1b
transmembrane and coiled-coil domain family 1b
chr12_-_8070969 0.14 ENSDART00000020995
tmem26b
transmembrane protein 26b
chr16_+_29492937 0.13 ENSDART00000011497
ctsk
cathepsin K
chr23_+_24272421 0.13 ENSDART00000029974
clcnk
chloride channel K
chr14_-_33348221 0.13 ENSDART00000187749
rpl39
ribosomal protein L39
chr1_-_1631399 0.13 ENSDART00000176787
clic6
chloride intracellular channel 6
chr8_+_47683539 0.13 ENSDART00000190701
dpp9
dipeptidyl-peptidase 9
chr16_-_36118514 0.13 ENSDART00000190427
mrps15
mitochondrial ribosomal protein S15
chr6_+_54711306 0.13 ENSDART00000074605
pkp1b
plakophilin 1b
chr7_+_55149001 0.13 ENSDART00000148642
cdh31
cadherin 31
chr9_-_12659140 0.13 ENSDART00000058565
pttg1ipb
PTTG1 interacting protein b
chr6_-_40899618 0.13 ENSDART00000153949
ENSDART00000021969
zgc:172271
zgc:172271
chr14_+_30774515 0.13 ENSDART00000191666
atl3
atlastin 3
chr21_-_26495700 0.13 ENSDART00000109379
cd248b
CD248 molecule, endosialin b
chr14_+_33413980 0.13 ENSDART00000052780
ENSDART00000124437
ENSDART00000173327
ndufa1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr19_+_48176745 0.13 ENSDART00000164963
prdm1b
PR domain containing 1b, with ZNF domain
chr16_-_33095161 0.13 ENSDART00000187648
dopey1
dopey family member 1
chr4_-_4250317 0.12 ENSDART00000103316
cd9b
CD9 molecule b
chr6_-_23931442 0.12 ENSDART00000160547
sec16b
SEC16 homolog B, endoplasmic reticulum export factor
chr6_-_8580857 0.12 ENSDART00000138858
ENSDART00000041142
myh11a
myosin, heavy chain 11a, smooth muscle
chr13_-_15994419 0.12 ENSDART00000079724
ENSDART00000042377
ENSDART00000046079
ENSDART00000050481
ENSDART00000016430
ikzf1
IKAROS family zinc finger 1 (Ikaros)
chr5_-_28968964 0.12 ENSDART00000184936
ENSDART00000016628
fam129bb
family with sequence similarity 129, member Bb
chr5_+_29160324 0.12 ENSDART00000137324
dpp7
dipeptidyl-peptidase 7
chr6_-_8489810 0.12 ENSDART00000124643
rasal3
RAS protein activator like 3
chr21_+_26657404 0.12 ENSDART00000129035
ENSDART00000186550
prdx5
peroxiredoxin 5
chr11_+_43740949 0.12 ENSDART00000189296
CU862021.1

chr21_+_31253048 0.12 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
asl
argininosuccinate lyase
chr9_+_33417969 0.12 ENSDART00000024795
gpr34b
G protein-coupled receptor 34b
chr21_+_27189490 0.12 ENSDART00000125349
bada
BCL2 associated agonist of cell death a
chr15_-_33834577 0.12 ENSDART00000163354
mmp13b
matrix metallopeptidase 13b
chr8_+_47683352 0.12 ENSDART00000187320
ENSDART00000192605
dpp9
dipeptidyl-peptidase 9
chr14_+_30753666 0.12 ENSDART00000009385
ENSDART00000137782
ENSDART00000172778
yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr21_-_20329541 0.12 ENSDART00000166049
slc26a1
solute carrier family 26 (anion exchanger), member 1
chr21_-_21781158 0.12 ENSDART00000113734
chrdl2
chordin-like 2
chr21_-_30166097 0.12 ENSDART00000130676
hbegfb
heparin-binding EGF-like growth factor b
chr11_-_21404044 0.12 ENSDART00000080116
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr20_-_26937453 0.12 ENSDART00000139756
ftr97
finTRIM family, member 97
chr16_+_19732543 0.12 ENSDART00000149901
ENSDART00000052927
twist1b
twist family bHLH transcription factor 1b
chr7_-_51368681 0.11 ENSDART00000146385
arhgap36
Rho GTPase activating protein 36
chr11_+_29965822 0.11 ENSDART00000127049
il1fma
interleukin-1 family member A
chr4_-_4261673 0.11 ENSDART00000150694
cd9b
CD9 molecule b
chr5_-_31942621 0.11 ENSDART00000049178
svopb
SV2 related protein b
chr20_+_29436601 0.11 ENSDART00000136804
fmn1
formin 1
chr7_+_65673885 0.11 ENSDART00000169182
parvab
parvin, alpha b
chr2_-_40191603 0.11 ENSDART00000180691
si:ch211-122l24.6
si:ch211-122l24.6
chr8_+_18464235 0.11 ENSDART00000110571
alkal1
ALK and LTK ligand 1
chr13_+_24717880 0.11 ENSDART00000147713
cfap43
cilia and flagella associated protein 43
chr14_+_30774894 0.11 ENSDART00000023054
atl3
atlastin 3
chr15_-_3963649 0.11 ENSDART00000172146
ENSDART00000171738
gpr171
G protein-coupled receptor 171
chr14_+_3522334 0.11 ENSDART00000164547
fnta
farnesyltransferase, CAAX box, alpha
chr4_+_3980247 0.11 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr8_+_10304981 0.11 ENSDART00000160766
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr11_+_24716837 0.11 ENSDART00000145217
zgc:153953
zgc:153953
chr10_-_26179805 0.11 ENSDART00000174797
trim3b
tripartite motif containing 3b
chr24_+_39990695 0.10 ENSDART00000040281
BX323854.1

chr11_-_25418856 0.10 ENSDART00000013714
gata1a
GATA binding protein 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of ikzf2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.4 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.6 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.2 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.1 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.3 GO:0030825 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.8 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.2 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.0 0.3 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.2 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.4 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.4 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0070378 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.0 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.1 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.2 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.6 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 1.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0097519 DNA recombinase complex(GO:0097519)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.2 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.5 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.8 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.0 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.0 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.0 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.0 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.