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PRJNA207719: Tissue specific transcriptome profiling

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Results for irf5

Z-value: 3.57

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Transcription factors associated with irf5

Gene Symbol Gene ID Gene Info
irf5
ENSDARG00000045681 interferon regulatory factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf5dr11_v1_chr4_-_13614797_136149360.856.6e-02Click!

Activity profile of irf5 motif

Sorted Z-values of irf5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_2039511 6.15 ENSDART00000160223
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr15_-_2640966 3.84 ENSDART00000063320
cldne
claudin e
chr7_+_69187585 3.04 ENSDART00000160499
ENSDART00000166258
marveld3
MARVEL domain containing 3
chr9_-_30264415 2.75 ENSDART00000060150
mid1ip1a
MID1 interacting protein 1a
chr10_-_22150419 2.74 ENSDART00000006173
cldn7b
claudin 7b
chr17_-_22552678 2.70 ENSDART00000079401
si:ch211-125o16.4
si:ch211-125o16.4
chr1_-_7582859 2.60 ENSDART00000110696
mxb
myxovirus (influenza) resistance B
chr7_-_19614916 2.45 ENSDART00000169029
zgc:194655
zgc:194655
chr1_-_7570181 2.42 ENSDART00000103588
mxa
myxovirus (influenza) resistance A
chr22_-_17688868 2.42 ENSDART00000012336
ENSDART00000147070
tjp3
tight junction protein 3
chr22_+_19218733 2.39 ENSDART00000183212
ENSDART00000133595
si:dkey-21e2.7
si:dkey-21e2.7
chr18_+_44532370 2.35 ENSDART00000086952
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr8_+_44475793 2.34 ENSDART00000190118
si:ch73-211l2.3
si:ch73-211l2.3
chr16_-_41990421 2.33 ENSDART00000055921
pycard
PYD and CARD domain containing
chr5_-_29531948 2.32 ENSDART00000098360
arrdc1a
arrestin domain containing 1a
chr23_-_31266586 2.30 ENSDART00000139746
si:dkey-261l7.2
si:dkey-261l7.2
chr15_-_17071328 2.29 ENSDART00000122617
si:ch211-24o10.6
si:ch211-24o10.6
chr16_+_41570653 2.26 ENSDART00000102665
aste1a
asteroid homolog 1a
chr15_-_29162193 2.24 ENSDART00000138449
ENSDART00000099885
xaf1
XIAP associated factor 1
chr4_-_77557279 2.23 ENSDART00000180113
AL935186.10

chr2_-_21438492 2.21 ENSDART00000046098
plcd1b
phospholipase C, delta 1b
chr16_-_45152169 2.20 ENSDART00000171452
si:ch73-343g19.4
si:ch73-343g19.4
chr15_-_33964897 2.15 ENSDART00000172075
ENSDART00000158126
ENSDART00000160456
lsr
lipolysis stimulated lipoprotein receptor
chr21_-_25295087 2.11 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr7_+_19615056 2.07 ENSDART00000124752
ENSDART00000190297
si:ch211-212k18.15
si:ch211-212k18.15
chr17_+_30894431 2.02 ENSDART00000127996
degs2
delta(4)-desaturase, sphingolipid 2
chr6_+_49771626 2.01 ENSDART00000134207
ctsz
cathepsin Z
chr20_-_26551210 2.01 ENSDART00000077715
si:dkey-25e12.3
si:dkey-25e12.3
chr23_+_642395 1.98 ENSDART00000186995
irf10
interferon regulatory factor 10
chr23_+_642001 1.92 ENSDART00000030643
ENSDART00000124850
irf10
interferon regulatory factor 10
chr7_+_19483277 1.92 ENSDART00000173750
si:ch211-212k18.7
si:ch211-212k18.7
chr23_-_29556844 1.91 ENSDART00000138021
rbp7a
retinol binding protein 7a, cellular
chr17_+_35362851 1.86 ENSDART00000137659
cmpk2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr10_+_15064433 1.85 ENSDART00000179978
parm1
prostate androgen-regulated mucin-like protein 1
chr8_-_14104317 1.84 ENSDART00000141635
si:ch211-229n2.6
si:ch211-229n2.6
chr7_-_67214972 1.81 ENSDART00000156861
swap70a
switching B cell complex subunit SWAP70a
chr10_+_2742499 1.79 ENSDART00000122847
grk5
G protein-coupled receptor kinase 5
chr18_+_44532883 1.79 ENSDART00000121994
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr18_+_44532199 1.78 ENSDART00000135386
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr5_-_30382925 1.77 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr6_+_49771372 1.74 ENSDART00000063251
ctsz
cathepsin Z
chr8_-_27687095 1.74 ENSDART00000086946
mov10b.1
Moloney leukemia virus 10b, tandem duplicate 1
chr7_+_49681040 1.74 ENSDART00000176372
ENSDART00000192172
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr15_-_21702317 1.73 ENSDART00000155824
IL4I1
si:dkey-40g16.6
chr9_+_41156818 1.69 ENSDART00000105764
ENSDART00000147052
stat4
signal transducer and activator of transcription 4
chr3_+_21200763 1.68 ENSDART00000067841
zgc:112038
zgc:112038
chr14_-_33277743 1.68 ENSDART00000048130
stard14
START domain containing 14
chr11_-_7261717 1.65 ENSDART00000128959
zgc:113223
zgc:113223
chr9_-_39968820 1.64 ENSDART00000100311
IKZF2
si:zfos-1425h8.1
chr10_-_15879569 1.64 ENSDART00000136789
tjp2a
tight junction protein 2a (zona occludens 2)
chr14_-_33278084 1.64 ENSDART00000132850
stard14
START domain containing 14
chr13_+_17694845 1.62 ENSDART00000079778
ifit8
interferon-induced protein with tetratricopeptide repeats 8
chr21_-_22543611 1.62 ENSDART00000177084
myo5b
myosin VB
chr4_-_68563862 1.59 ENSDART00000182970
BX548011.2

chr7_-_20103384 1.59 ENSDART00000052902
acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr20_+_26683933 1.54 ENSDART00000139852
ENSDART00000077751
foxq1b
forkhead box Q1b
chr24_-_36680261 1.53 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr16_+_19637384 1.51 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr16_+_41517188 1.51 ENSDART00000049976
si:dkey-11p23.7
si:dkey-11p23.7
chr1_+_40140498 1.45 ENSDART00000101640
zgc:152658
zgc:152658
chr2_+_42708674 1.45 ENSDART00000141989
ENSDART00000005767
ftr11
finTRIM family, member 11
chr1_+_38153944 1.44 ENSDART00000135666
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr4_-_11580948 1.42 ENSDART00000049066
net1
neuroepithelial cell transforming 1
chr7_+_19482877 1.40 ENSDART00000077868
si:ch211-212k18.7
si:ch211-212k18.7
chr14_-_1432875 1.39 ENSDART00000164408
ENSDART00000159774
zgc:152774
zgc:152774
chr20_+_6535438 1.39 ENSDART00000145763
si:ch211-191a24.4
si:ch211-191a24.4
chr16_+_29492937 1.35 ENSDART00000011497
ctsk
cathepsin K
chr2_-_37140423 1.34 ENSDART00000144220
tspan37
tetraspanin 37
chr6_-_1777831 1.33 ENSDART00000167390
zgc:113442
zgc:113442
chr5_-_12587053 1.30 ENSDART00000162780
vsig10
V-set and immunoglobulin domain containing 10
chr18_+_44532668 1.30 ENSDART00000140672
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr3_+_25191467 1.27 ENSDART00000156956
ENSDART00000154799
il2rb
interleukin 2 receptor, beta
chr6_-_33916756 1.26 ENSDART00000137447
ENSDART00000138488
nasp
nuclear autoantigenic sperm protein (histone-binding)
chr3_+_29941777 1.26 ENSDART00000113889
ifi35
interferon-induced protein 35
chr20_+_6535176 1.25 ENSDART00000054652
si:ch211-191a24.4
si:ch211-191a24.4
chr10_+_110868 1.24 ENSDART00000135572
ENSDART00000190467
ENSDART00000056672
pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_47161996 1.24 ENSDART00000053153
mhc1zba
major histocompatibility complex class I ZBA
chr3_+_25999477 1.20 ENSDART00000024316
mcm5
minichromosome maintenance complex component 5
chr13_-_37631092 1.18 ENSDART00000108855
si:dkey-188i13.7
si:dkey-188i13.7
chr17_+_1627379 1.15 ENSDART00000184050
LO018432.1

chr7_-_26579465 1.14 ENSDART00000173820
si:dkey-62k3.6
si:dkey-62k3.6
chr9_+_3055566 1.14 ENSDART00000189906
ENSDART00000175891
ENSDART00000093021
ppp1r9ala
protein phosphatase 1 regulatory subunit 9A-like A
chr2_-_13333932 1.12 ENSDART00000150238
ENSDART00000168258
si:dkey-185p13.1
vps4b
si:dkey-185p13.1
vacuolar protein sorting 4b homolog B (S. cerevisiae)
chr16_-_32303835 1.12 ENSDART00000191408
mms22l
MMS22-like, DNA repair protein
chr15_+_1534644 1.12 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr14_-_33585809 1.10 ENSDART00000023540
sash3
SAM and SH3 domain containing 3
chr9_+_23765587 1.10 ENSDART00000145120
si:ch211-219a4.3
si:ch211-219a4.3
chr13_+_30692669 1.08 ENSDART00000187818
CR762483.1

chr20_+_36806398 1.07 ENSDART00000153317
abracl
ABRA C-terminal like
chr9_-_23765480 1.04 ENSDART00000027212
si:ch211-219a4.6
si:ch211-219a4.6
chr22_-_17499513 1.03 ENSDART00000105460
si:ch211-197g15.6
si:ch211-197g15.6
chr23_+_2666944 1.02 ENSDART00000192861
CABZ01057928.1

chr6_+_48348415 1.00 ENSDART00000064826
mov10a
Mov10 RISC complex RNA helicase a
chr16_+_42772678 1.00 ENSDART00000155575
si:ch211-135n15.2
si:ch211-135n15.2
chr24_-_34680956 1.00 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr12_-_27242498 0.99 ENSDART00000152609
ENSDART00000152170
si:dkey-11c5.11
si:dkey-11c5.11
chr5_+_58455488 0.98 ENSDART00000038602
ENSDART00000127958
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr3_-_29508959 0.98 ENSDART00000055408
cyth4a
cytohesin 4a
chr18_+_45708744 0.97 ENSDART00000077341
depdc7
DEP domain containing 7
chr5_-_69716501 0.97 ENSDART00000158956
mob1a
MOB kinase activator 1A
chr12_-_23658888 0.97 ENSDART00000088319
map3k8
mitogen-activated protein kinase kinase kinase 8
chr7_+_54222156 0.96 ENSDART00000165201
ENSDART00000158518
pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr5_-_37959874 0.94 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr9_+_890536 0.94 ENSDART00000139132
steap3
STEAP family member 3, metalloreductase
chr25_+_19720228 0.93 ENSDART00000181804
mxd
myxovirus (influenza virus) resistance D
chr19_+_14113886 0.93 ENSDART00000169343
kdf1b
keratinocyte differentiation factor 1b
chr3_-_4501026 0.92 ENSDART00000163052
zgc:162198
zgc:162198
chr25_-_483808 0.92 ENSDART00000104720
si:ch1073-385f13.3
si:ch1073-385f13.3
chr7_+_19600262 0.90 ENSDART00000007310
zgc:171731
zgc:171731
chr22_-_30973791 0.90 ENSDART00000104728
ssuh2.2
ssu-2 homolog, tandem duplicate 2
chr5_+_66326004 0.89 ENSDART00000144351
malt1
MALT paracaspase 1
chr4_-_17669881 0.89 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr22_-_6499055 0.88 ENSDART00000142235
ENSDART00000183588
si:dkey-19a16.7
si:dkey-19a16.7
chr5_-_26187097 0.88 ENSDART00000137027
ccdc125
coiled-coil domain containing 125
chr2_+_37975026 0.86 ENSDART00000034802
si:rp71-1g18.13
si:rp71-1g18.13
chr19_-_15420678 0.86 ENSDART00000151454
ENSDART00000027697
serinc2
serine incorporator 2
chr13_-_33700461 0.84 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr3_+_32125452 0.83 ENSDART00000110396
zgc:194125
zgc:194125
chr2_-_41861040 0.82 ENSDART00000045763
keap1a
kelch-like ECH-associated protein 1a
chr15_-_40175894 0.81 ENSDART00000156632
si:ch211-281l24.3
si:ch211-281l24.3
chr24_-_26310854 0.81 ENSDART00000080113
apodb
apolipoprotein Db
chr13_-_50200042 0.80 ENSDART00000074230
pkz
protein kinase containing Z-DNA binding domains
chr6_-_49983329 0.80 ENSDART00000113083
asip1
agouti signaling protein 1
chr18_+_45666489 0.79 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr7_+_46020508 0.78 ENSDART00000170294
ccne1
cyclin E1
chr25_+_8447565 0.78 ENSDART00000142090
fanci
Fanconi anemia, complementation group I
chr12_+_17154655 0.76 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr15_+_44201056 0.76 ENSDART00000162433
ENSDART00000148336
CU655961.4

chr10_-_2971407 0.75 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr22_-_17474583 0.75 ENSDART00000148027
si:ch211-197g15.8
si:ch211-197g15.8
chr1_+_58290933 0.74 ENSDART00000140536
si:dkey-222h21.6
si:dkey-222h21.6
chr21_+_11535304 0.73 ENSDART00000158901
ENSDART00000081600
cd8b
cd8 beta
chr2_-_47870649 0.73 ENSDART00000142854
ftr05
finTRIM family, member 5
chr15_+_714203 0.73 ENSDART00000153847
si:dkey-7i4.24
si:dkey-7i4.24
chr18_-_16922905 0.72 ENSDART00000187165
wee1
WEE1 G2 checkpoint kinase
chr11_-_42472941 0.72 ENSDART00000166624
arf4b
ADP-ribosylation factor 4b
chr3_+_32571929 0.71 ENSDART00000151025
si:ch73-248e21.1
si:ch73-248e21.1
chr1_-_49530615 0.71 ENSDART00000113315
si:ch211-281g13.5
si:ch211-281g13.5
chr19_+_17386393 0.70 ENSDART00000034837
rpl15
ribosomal protein L15
chr3_-_29941357 0.70 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
grna
granulin a
chr25_+_28862660 0.68 ENSDART00000154681
si:ch211-106e7.2
si:ch211-106e7.2
chr3_+_32135037 0.68 ENSDART00000110490
BX511021.1

chr20_-_43743700 0.67 ENSDART00000100620
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr14_+_22076596 0.67 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
slc43a1a
solute carrier family 43 (amino acid system L transporter), member 1a
chr24_-_26885897 0.66 ENSDART00000180512
fndc3bb
fibronectin type III domain containing 3Bb
chr24_+_16983269 0.65 ENSDART00000139176
ENSDART00000023833
eif2s3
eukaryotic translation initiation factor 2, subunit 3 gamma
chr3_+_32139666 0.65 ENSDART00000109791
zgc:92066
zgc:92066
chr12_-_33805366 0.64 ENSDART00000030566
galk1
galactokinase 1
chr22_-_4439311 0.64 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr16_-_30903930 0.64 ENSDART00000143996
dennd3b
DENN/MADD domain containing 3b
chr15_-_1835189 0.63 ENSDART00000154369
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr24_+_22731228 0.61 ENSDART00000146733
si:dkey-225k4.1
si:dkey-225k4.1
chr25_-_774350 0.61 ENSDART00000166321
ENSDART00000160386
IRAK4
interleukin 1 receptor associated kinase 4
chr25_+_27410352 0.60 ENSDART00000154362
pot1
protection of telomeres 1 homolog
chr10_+_2587234 0.59 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr10_+_4046448 0.59 ENSDART00000123086
ENSDART00000052268
pitpnb
phosphatidylinositol transfer protein, beta
chr16_+_26601364 0.59 ENSDART00000087537
epb41l4b
erythrocyte membrane protein band 4.1 like 4B
chr16_+_33144306 0.59 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr12_-_41759686 0.58 ENSDART00000172175
ENSDART00000165152
ppp2r2d
protein phosphatase 2, regulatory subunit B, delta
chr8_-_49304602 0.58 ENSDART00000147020
prickle3
prickle homolog 3
chr24_+_11334733 0.58 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
si:dkey-12l12.1
chr11_-_20071642 0.58 ENSDART00000162931
ENSDART00000159928
ENSDART00000191443
ENSDART00000121722
si:dkey-274m17.3
si:dkey-274m17.3
chr12_-_35936329 0.57 ENSDART00000166634
rnf213b
ring finger protein 213b
chr17_-_12966907 0.57 ENSDART00000022874
psma6a
proteasome subunit alpha 6a
chr8_+_45361775 0.54 ENSDART00000015193
chmp4bb
charged multivesicular body protein 4Bb
chr7_-_6444011 0.54 ENSDART00000173010
zgc:112234
zgc:112234
chr8_+_17168114 0.53 ENSDART00000183901
cenph
centromere protein H
chr21_+_43253538 0.53 ENSDART00000179940
ENSDART00000164806
ENSDART00000147026
shroom1
shroom family member 1
chr15_-_1484795 0.53 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr17_-_30666037 0.52 ENSDART00000156509
alkal2b
ALK and LTK ligand 2b
chr13_+_2523032 0.52 ENSDART00000172261
lhb
luteinizing hormone, beta polypeptide
chr16_+_35595312 0.52 ENSDART00000170438
si:ch211-1i11.3
si:ch211-1i11.3
chr19_-_7690975 0.52 ENSDART00000151384
si:dkey-204a24.10
si:dkey-204a24.10
chr2_+_47927026 0.52 ENSDART00000143023
ftr25
finTRIM family, member 25
chr7_+_8670398 0.51 ENSDART00000164195
si:ch211-1o7.2
si:ch211-1o7.2
chr5_+_50913357 0.51 ENSDART00000092938
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr25_+_5983430 0.51 ENSDART00000074814
ppib
peptidylprolyl isomerase B (cyclophilin B)
chr24_+_7782313 0.50 ENSDART00000111090
ptprh
protein tyrosine phosphatase, receptor type, h
chr1_+_58332000 0.50 ENSDART00000145234
ggt1l2.1
gamma-glutamyltransferase 1 like 2.1
chr11_-_6206520 0.47 ENSDART00000150199
ENSDART00000148246
ENSDART00000019440
pole4
polymerase (DNA-directed), epsilon 4, accessory subunit
chr16_-_25829779 0.46 ENSDART00000086301
irge4
immunity-related GTPase family, e4
chr20_+_1316495 0.46 ENSDART00000064439
nup43
nucleoporin 43
chr17_+_46739693 0.45 ENSDART00000097810
pimr22
Pim proto-oncogene, serine/threonine kinase, related 22
chr7_-_6441865 0.45 ENSDART00000172831
hist1h2a10
histone cluster 1 H2A family member 10
chr22_+_336256 0.45 ENSDART00000019155
btg2
B-cell translocation gene 2
chr9_+_23003208 0.44 ENSDART00000021060
eaf2
ELL associated factor 2
chr8_+_20157798 0.44 ENSDART00000124809
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr14_+_16345003 0.44 ENSDART00000003040
ENSDART00000165193
itln3
intelectin 3
chr12_-_17035339 0.44 ENSDART00000152814
ifit9
interferon-induced protein with tetratricopeptide repeats 9
chr19_-_42462491 0.44 ENSDART00000131715
psmb4
proteasome subunit beta 4
chr2_+_27403300 0.44 ENSDART00000099180
elovl8a
ELOVL fatty acid elongase 8a
chr16_-_31644545 0.43 ENSDART00000181634
CR855311.5

chr25_+_20272145 0.43 ENSDART00000109605
si:dkey-219c3.2
si:dkey-219c3.2
chr21_+_19844195 0.43 ENSDART00000065674
ENSDART00000157188
fybb
FYN binding protein b
chr21_+_21010786 0.43 ENSDART00000079692
ndr1
nodal-related 1
chr11_-_13107106 0.42 ENSDART00000184477
elovl1b
ELOVL fatty acid elongase 1b
chr23_-_29553430 0.42 ENSDART00000157773
ENSDART00000126384
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr7_+_13995792 0.42 ENSDART00000091470
furina
furin (paired basic amino acid cleaving enzyme) a
chr22_-_17474781 0.42 ENSDART00000186817
si:ch211-197g15.8
si:ch211-197g15.8
chr7_+_3171585 0.41 ENSDART00000138299
si:dkey-201l21.4
si:dkey-201l21.4

Network of associatons between targets according to the STRING database.

First level regulatory network of irf5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.6 1.9 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.6 1.8 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.5 2.7 GO:0060876 semicircular canal formation(GO:0060876)
0.4 1.6 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4 1.8 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.3 1.7 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 1.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 6.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 1.5 GO:0045124 regulation of bone resorption(GO:0045124)
0.3 0.6 GO:0051972 regulation of telomerase activity(GO:0051972)
0.3 0.8 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.2 2.4 GO:0030104 water homeostasis(GO:0030104)
0.2 0.9 GO:0015677 copper ion import(GO:0015677)
0.2 0.9 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 0.5 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.2 0.7 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 6.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 2.0 GO:0034311 diol metabolic process(GO:0034311)
0.1 1.5 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.1 0.3 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 0.6 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 1.0 GO:0014028 notochord formation(GO:0014028)
0.1 1.8 GO:0048382 mesendoderm development(GO:0048382)
0.1 0.6 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.5 GO:0032728 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.5 GO:0070375 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1 1.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 3.8 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.8 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 1.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 2.3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 2.3 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.6 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.5 GO:0031179 peptide modification(GO:0031179)
0.1 8.6 GO:0051604 protein maturation(GO:0051604)
0.1 0.2 GO:0008584 male gonad development(GO:0008584)
0.1 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 3.4 GO:0051607 defense response to virus(GO:0051607)
0.1 1.1 GO:0031297 replication fork processing(GO:0031297)
0.1 0.3 GO:0030728 ovulation(GO:0030728)
0.0 0.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 2.5 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 0.4 GO:0014812 muscle cell migration(GO:0014812)
0.0 0.2 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.9 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0 0.2 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 2.1 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 1.7 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.1 GO:0042476 odontogenesis(GO:0042476)
0.0 0.9 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.3 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 1.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 2.2 GO:0007492 endoderm development(GO:0007492)
0.0 2.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.0 GO:0000302 response to reactive oxygen species(GO:0000302)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 2.2 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.8 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.7 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.2 GO:0060348 bone development(GO:0060348)
0.0 0.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.0 GO:0001894 tissue homeostasis(GO:0001894)
0.0 0.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.3 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0061702 inflammasome complex(GO:0061702)
0.5 2.7 GO:0043034 costamere(GO:0043034)
0.3 6.0 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 0.8 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.2 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 2.3 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.8 GO:0016234 inclusion body(GO:0016234)
0.1 13.7 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 2.7 GO:0043186 P granule(GO:0043186)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 2.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.6 GO:0000792 heterochromatin(GO:0000792)
0.0 0.5 GO:0043296 apical junction complex(GO:0043296)
0.0 2.1 GO:0005770 late endosome(GO:0005770)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.5 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.7 GO:0005764 lysosome(GO:0005764)
0.0 0.3 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.6 1.9 GO:0009041 uridylate kinase activity(GO:0009041)
0.6 1.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.5 2.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3 1.0 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3 1.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 0.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 1.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 2.5 GO:0031386 protein tag(GO:0031386)
0.2 2.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.8 GO:0031779 melanocortin receptor binding(GO:0031779)
0.1 1.8 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.2 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 1.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.5 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 1.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 14.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 0.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 6.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.5 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 2.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 1.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.4 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.1 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 3.9 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 6.3 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.1 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 3.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 5.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 3.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.7 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.6 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint