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PRJNA207719: Tissue specific transcriptome profiling

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Results for isl1+isl1l

Z-value: 0.86

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Transcription factors associated with isl1+isl1l

Gene Symbol Gene ID Gene Info
isl1
ENSDARG00000004023 ISL LIM homeobox 1
isl1l
ENSDARG00000021055 islet1, like
isl1l
ENSDARG00000110204 islet1, like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
isl1ldr11_v1_chr10_+_8680730_86807300.108.7e-01Click!
isl1dr11_v1_chr5_-_40734045_40734045-0.019.9e-01Click!

Activity profile of isl1+isl1l motif

Sorted Z-values of isl1+isl1l motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_11457500 0.47 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr1_-_25679339 0.45 ENSDART00000161703
ENSDART00000054230
fgg
fibrinogen gamma chain
chr14_+_21222287 0.41 ENSDART00000159905
si:ch211-175m2.4
si:ch211-175m2.4
chr16_-_29387215 0.36 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr6_-_27123327 0.36 ENSDART00000073881
agxta
alanine-glyoxylate aminotransferase a
chr22_+_19220459 0.34 ENSDART00000163070
si:dkey-21e2.7
si:dkey-21e2.7
chr19_+_10855158 0.31 ENSDART00000172219
ENSDART00000170826
apoea
apolipoprotein Ea
chr13_+_46941930 0.29 ENSDART00000056962
fbxo5
F-box protein 5
chr7_-_38664947 0.26 ENSDART00000100546
ENSDART00000112405
c6ast1
six-cysteine containing astacin protease 1
chr6_-_346084 0.26 ENSDART00000162599
pde6ha
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr7_+_36035432 0.26 ENSDART00000179004
irx3a
iroquois homeobox 3a
chr7_+_13988075 0.26 ENSDART00000186812
furina
furin (paired basic amino acid cleaving enzyme) a
chr19_-_47570672 0.24 ENSDART00000112155
rrm2
ribonucleotide reductase M2 polypeptide
chr4_+_2230701 0.23 ENSDART00000080439
cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr14_-_1454045 0.23 ENSDART00000161460
pmt
phosphoethanolamine methyltransferase
chr17_+_33375469 0.22 ENSDART00000032827
zgc:162964
zgc:162964
chr12_+_22672323 0.22 ENSDART00000123808
ENSDART00000159864
cdca9
cell division cycle associated 9
chr1_-_59348118 0.22 ENSDART00000170901
cyp3a65
cytochrome P450, family 3, subfamily A, polypeptide 65
chr12_-_13205854 0.21 ENSDART00000077829
pelo
pelota mRNA surveillance and ribosome rescue factor
chr1_-_45146834 0.21 ENSDART00000144997
si:ch211-239f4.6
si:ch211-239f4.6
chr5_+_32345187 0.21 ENSDART00000147132
c9
complement component 9
chr10_-_2943474 0.21 ENSDART00000188698
oclna
occludin a
chr5_-_41831646 0.20 ENSDART00000134326
si:dkey-65b12.6
si:dkey-65b12.6
chr11_-_438294 0.20 ENSDART00000040812
nuf2
NUF2, NDC80 kinetochore complex component, homolog
chr20_-_45709990 0.19 ENSDART00000027482
gpcpd1
glycerophosphocholine phosphodiesterase 1
chr15_-_44052927 0.19 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr20_+_23440632 0.19 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr19_+_10331325 0.18 ENSDART00000143930
tmem238a
transmembrane protein 238a
chr3_-_32956808 0.18 ENSDART00000183902
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr16_-_55259199 0.18 ENSDART00000161130
iqgap3
IQ motif containing GTPase activating protein 3
chr4_-_5826320 0.17 ENSDART00000165354
foxm1
forkhead box M1
chr23_+_26142613 0.16 ENSDART00000165046
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr24_-_32665283 0.16 ENSDART00000038364
ca2
carbonic anhydrase II
chr9_-_35633827 0.16 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr5_-_30615901 0.16 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr5_-_64203101 0.16 ENSDART00000029364
ak5l
adenylate kinase 5, like
chr22_-_36875264 0.16 ENSDART00000137548
kng1
kininogen 1
chr5_-_41838354 0.16 ENSDART00000146793
si:dkey-65b12.6
si:dkey-65b12.6
chr20_+_34770197 0.16 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr21_+_31253048 0.15 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
asl
argininosuccinate lyase
chr23_-_45398622 0.15 ENSDART00000053571
ENSDART00000149464
zgc:100911
zgc:100911
chr8_+_21254192 0.15 ENSDART00000167718
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr14_-_36799280 0.14 ENSDART00000168615
rnf130
ring finger protein 130
chr8_-_14121634 0.14 ENSDART00000184946
bgna
biglycan a
chr12_-_19028046 0.14 ENSDART00000142253
ENSDART00000078484
rangap1b
Ran GTPase activating protein 1b
chr8_+_53064920 0.14 ENSDART00000164823
nadka
NAD kinase a
chr7_+_38897836 0.14 ENSDART00000024330
creb3l1
cAMP responsive element binding protein 3-like 1
chr3_-_56871984 0.14 ENSDART00000189908
ENSDART00000183146
ENSDART00000183087
zgc:112148
zgc:112148
chr17_-_4252221 0.14 ENSDART00000152020
gdf3
growth differentiation factor 3
chr5_+_31168096 0.14 ENSDART00000086443
ENSDART00000192271
atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr3_+_15505275 0.13 ENSDART00000141714
nupr1
nuclear protein 1
chr7_+_4538334 0.13 ENSDART00000139326
ENSDART00000146915
si:dkey-83f18.9
si:dkey-83f18.9
chr19_-_6193448 0.13 ENSDART00000151405
erf
Ets2 repressor factor
chr17_+_39741926 0.13 ENSDART00000154996
ENSDART00000154599
si:dkey-229e3.2
si:dkey-229e3.2
chr20_-_35012093 0.13 ENSDART00000062761
cnstb
consortin, connexin sorting protein b
chr20_-_25522911 0.13 ENSDART00000063058
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr20_+_2281933 0.13 ENSDART00000137579
si:ch73-18b11.2
si:ch73-18b11.2
chr14_+_1240419 0.12 ENSDART00000181248
adad1
adenosine deaminase domain containing 1 (testis-specific)
chr17_-_2036850 0.12 ENSDART00000186048
ENSDART00000188838
ENSDART00000186423
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr14_+_16287968 0.12 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr20_+_37794633 0.12 ENSDART00000022060
atf3
activating transcription factor 3
chr4_-_75707991 0.12 ENSDART00000166358
ENSDART00000160021
si:dkey-165o8.2
si:dkey-165o8.2
chr7_+_53541173 0.12 ENSDART00000159449
gramd2aa
GRAM domain containing 2Aa
chr16_+_52999778 0.12 ENSDART00000011506
nkd2a
naked cuticle homolog 2a
chr12_-_13205572 0.11 ENSDART00000152670
pelo
pelota mRNA surveillance and ribosome rescue factor
chr4_+_17280868 0.11 ENSDART00000145349
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr23_+_26142807 0.11 ENSDART00000158878
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr10_+_35352435 0.11 ENSDART00000123936
si:dkey-259j3.5
si:dkey-259j3.5
chr5_+_51443009 0.11 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr6_+_612594 0.11 ENSDART00000150903
kynu
kynureninase
chr12_-_36521767 0.11 ENSDART00000110290
unc13d
unc-13 homolog D (C. elegans)
chr8_+_4798158 0.11 ENSDART00000031650
hsp70l
heat shock cognate 70-kd protein, like
chr22_-_621888 0.10 ENSDART00000135829
srsf3b
serine/arginine-rich splicing factor 3b
chr14_+_20893065 0.10 ENSDART00000079452
lygl1
lysozyme g-like 1
chr25_+_30131055 0.10 ENSDART00000152705
api5
apoptosis inhibitor 5
chr10_+_38708099 0.10 ENSDART00000172306
tmprss2
transmembrane protease, serine 2
chr22_-_26852516 0.10 ENSDART00000005829
gde1
glycerophosphodiester phosphodiesterase 1
chr3_-_36209936 0.10 ENSDART00000175208
csnk1da
casein kinase 1, delta a
chr23_+_4022620 0.10 ENSDART00000055099
b4galt5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr8_-_4100365 0.10 ENSDART00000142846
cux2b
cut-like homeobox 2b
chr3_-_8012847 0.10 ENSDART00000169673
si:ch211-175l6.1
si:ch211-175l6.1
chr2_-_17114852 0.10 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr24_-_33308045 0.10 ENSDART00000149711
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr10_-_36808348 0.10 ENSDART00000099320
dhrs13a.1
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr7_-_54679595 0.09 ENSDART00000165320
ccnd1
cyclin D1
chr1_+_41588170 0.09 ENSDART00000139175
si:dkey-56e3.2
si:dkey-56e3.2
chr6_-_436658 0.09 ENSDART00000191515
grap2b
GRB2-related adaptor protein 2b
chr10_-_17587832 0.09 ENSDART00000113101
smarcad1b
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 b
chr23_-_31372639 0.09 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
hmgn3
high mobility group nucleosomal binding domain 3
chr3_-_23513155 0.09 ENSDART00000170200
BX682558.1

chr21_+_26522571 0.09 ENSDART00000134617
adssl
adenylosuccinate synthase, like
chr12_+_13205955 0.09 ENSDART00000092906
ppp1cab
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr3_-_17716322 0.09 ENSDART00000192664
CABZ01018956.1

chr17_-_36529016 0.09 ENSDART00000025019
colec11
collectin sub-family member 11
chr7_+_4523051 0.09 ENSDART00000140860
ENSDART00000143778
si:dkey-83f18.10
si:dkey-83f18.10
chr5_-_42083363 0.09 ENSDART00000162596
cxcl11.5
chemokine (C-X-C motif) ligand 11, duplicate 5
chr11_-_37997419 0.09 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr7_-_71585065 0.09 ENSDART00000128678
mettl4
methyltransferase like 4
chr23_+_20431140 0.09 ENSDART00000193950
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr9_-_14137295 0.08 ENSDART00000127640
ENSDART00000189018
ENSDART00000188985
ttll4
tubulin tyrosine ligase-like family, member 4
chr11_-_31226578 0.08 ENSDART00000109698
nacc1b
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr5_+_26795773 0.08 ENSDART00000145631
tcn2
transcobalamin II
chr14_+_23709134 0.08 ENSDART00000191162
ENSDART00000179754
ENSDART00000054266
gnpda1
glucosamine-6-phosphate deaminase 1
chr1_-_23596391 0.08 ENSDART00000155184
lcorl
ligand dependent nuclear receptor corepressor-like
chr17_+_42274825 0.08 ENSDART00000020156
pax1a
paired box 1a
chr3_+_8224622 0.08 ENSDART00000138670
si:ch73-379f5.5
si:ch73-379f5.5
chr4_+_3980247 0.08 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr23_+_36063599 0.08 ENSDART00000103147
hoxc12a
homeobox C12a
chr8_-_30338872 0.08 ENSDART00000137583
dock8
dedicator of cytokinesis 8
chr2_-_36925561 0.08 ENSDART00000187690
map1sb
microtubule-associated protein 1Sb
chr16_-_46619967 0.08 ENSDART00000158341
tmem176l.3a
transmembrane protein 176l.3a
chr22_-_31020690 0.08 ENSDART00000130604
ssuh2.4
ssu-2 homolog, tandem duplicate 4
chr5_+_22393501 0.08 ENSDART00000185276
si:dkey-27p18.7
si:dkey-27p18.7
chr2_+_36112273 0.08 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr8_+_48942470 0.08 ENSDART00000005464
ENSDART00000132035
rer1
retention in endoplasmic reticulum sorting receptor 1
chr8_-_25033681 0.08 ENSDART00000003493
nfyal
nuclear transcription factor Y, alpha, like
chr3_+_12718100 0.08 ENSDART00000162343
ENSDART00000192425
cyp2k20
cytochrome P450, family 2, subfamily k, polypeptide 20
chr9_+_14152211 0.08 ENSDART00000148055
si:ch211-67e16.11
si:ch211-67e16.11
chr25_-_27541621 0.07 ENSDART00000130678
spam1
sperm adhesion molecule 1
chr4_+_9478500 0.07 ENSDART00000030738
lmf2b
lipase maturation factor 2b
chr4_+_76705830 0.07 ENSDART00000064312
ms4a17a.7
membrane-spanning 4-domains, subfamily A, member 17A.7
chr17_+_6563307 0.07 ENSDART00000156454
adgrf3a
adhesion G protein-coupled receptor F3a
chr6_+_22326624 0.07 ENSDART00000020333
rae1
ribonucleic acid export 1
chr9_+_30478768 0.07 ENSDART00000101097
acp6
acid phosphatase 6, lysophosphatidic
chr3_+_22377312 0.07 ENSDART00000155597
arhgap27l
Rho GTPase activating protein 27, like
chr10_-_10018120 0.07 ENSDART00000132375
strbp
spermatid perinuclear RNA binding protein
chr22_-_16755885 0.07 ENSDART00000036467
patj
PATJ, crumbs cell polarity complex component
chr4_+_15968483 0.06 ENSDART00000101575
si:dkey-117n7.5
si:dkey-117n7.5
chr16_-_30903930 0.06 ENSDART00000143996
dennd3b
DENN/MADD domain containing 3b
chr21_+_28958471 0.06 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr20_+_29209926 0.06 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr22_+_6149121 0.06 ENSDART00000134067
si:dkey-19a16.5
si:dkey-19a16.5
chr16_+_14029283 0.06 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr22_-_17653143 0.06 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr22_-_3299100 0.06 ENSDART00000160305
si:zfos-943e10.1
si:zfos-943e10.1
chr12_-_10505986 0.06 ENSDART00000152672
zgc:152977
zgc:152977
chr18_+_15132112 0.06 ENSDART00000099764
zgc:153031
zgc:153031
chr14_-_36437249 0.06 ENSDART00000016728
aga
aspartylglucosaminidase
chr22_-_19504690 0.06 ENSDART00000166296
si:dkey-78l4.11
si:dkey-78l4.11
chr20_-_38446891 0.06 ENSDART00000192013
itpkb
inositol-trisphosphate 3-kinase B
chr13_+_48359573 0.06 ENSDART00000161959
ENSDART00000165311
msh6
mutS homolog 6 (E. coli)
chr10_-_43718914 0.05 ENSDART00000189277
cetn3
centrin 3
chr22_-_24984733 0.05 ENSDART00000142147
ENSDART00000187284
dnal4b
dynein, axonemal, light chain 4b
chr19_-_7272921 0.05 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
rxrba
retinoid x receptor, beta a
chr8_+_20140321 0.05 ENSDART00000012120
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr17_-_46457622 0.05 ENSDART00000130215
TMEM179 (1 of many)
transmembrane protein 179
chr21_-_43606502 0.05 ENSDART00000151030
si:ch73-362m14.4
si:ch73-362m14.4
chr21_-_4922981 0.05 ENSDART00000191819
ENSDART00000113556
ENSDART00000193269
ENSDART00000182961
kcnt1
potassium channel, subfamily T, member 1
chr4_-_15103646 0.05 ENSDART00000138183
ENSDART00000181044
nrf1
nuclear respiratory factor 1
chr21_-_30408775 0.05 ENSDART00000101037
nhp2
NHP2 ribonucleoprotein homolog (yeast)
chr7_+_3872189 0.05 ENSDART00000064221
si:dkey-88n24.5
si:dkey-88n24.5
chr2_+_11685742 0.05 ENSDART00000138562
greb1l
growth regulation by estrogen in breast cancer-like
chr9_+_44430974 0.05 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr21_-_4923427 0.05 ENSDART00000181489
kcnt1
potassium channel, subfamily T, member 1
chr11_-_18107447 0.05 ENSDART00000187376
qrich1
glutamine-rich 1
chr2_+_27010439 0.05 ENSDART00000030547
cdh7a
cadherin 7a
chr11_-_35975026 0.05 ENSDART00000186219
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b
chr4_+_71086017 0.05 ENSDART00000159113
si:dkeyp-80d11.10
si:dkeyp-80d11.10
chr19_-_48019366 0.05 ENSDART00000169429
si:ch1073-205c8.5
si:ch1073-205c8.5
chr14_-_31693148 0.05 ENSDART00000172958
map7d3
MAP7 domain containing 3
chr6_-_18618106 0.05 ENSDART00000161562
znf207b
zinc finger protein 207, b
chr1_-_12397258 0.05 ENSDART00000144596
sclt1
sodium channel and clathrin linker 1
chr13_-_42536642 0.05 ENSDART00000134533
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr7_+_26998169 0.05 ENSDART00000128110
ENSDART00000101018
caprin1a
cell cycle associated protein 1a
chr23_-_38497705 0.05 ENSDART00000109493
tshz2
teashirt zinc finger homeobox 2
chr4_+_15899668 0.05 ENSDART00000101592
col7a1l
collagen type VII alpha 1-like
chr8_+_18830759 0.05 ENSDART00000089079
mpnd
MPN domain containing
chr21_-_35325466 0.05 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr11_+_21587950 0.05 ENSDART00000162251
FAM72B
zgc:101564
chr22_-_14115292 0.04 ENSDART00000105717
ENSDART00000165670
aox5
aldehyde oxidase 5
chr9_+_54695981 0.04 ENSDART00000183605
rab9a
RAB9A, member RAS oncogene family
chr17_+_44756247 0.04 ENSDART00000153773
cipca
CLOCK-interacting pacemaker a
chr4_-_12930086 0.04 ENSDART00000013604
lemd3
LEM domain containing 3
chr17_+_28340138 0.04 ENSDART00000033943
mdga2a
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr5_+_9360394 0.04 ENSDART00000124642
FP236810.2

chr7_+_15871156 0.04 ENSDART00000145946
pax6b
paired box 6b
chr11_+_45110865 0.04 ENSDART00000158188
mgea5l
meningioma expressed antigen 5 (hyaluronidase) like
chr13_+_15701849 0.04 ENSDART00000003517
trmt61a
tRNA methyltransferase 61A
chr7_+_8543317 0.04 ENSDART00000114998
jac8
jacalin 8
chr12_+_36416173 0.04 ENSDART00000190278
unk
unkempt family zinc finger
chr21_-_39327223 0.04 ENSDART00000115097
aifm5
apoptosis-inducing factor, mitochondrion-associated, 5
chr16_+_24626448 0.04 ENSDART00000153591
si:dkey-56f14.7
si:dkey-56f14.7
chr4_-_890220 0.04 ENSDART00000022668
aim1b
crystallin beta-gamma domain containing 1b
chr20_+_25712276 0.04 ENSDART00000121585
ENSDART00000185772
cep135
centrosomal protein 135
chr1_+_22174251 0.04 ENSDART00000137429
dnah6
dynein, axonemal, heavy chain 6
chr12_+_7491690 0.04 ENSDART00000152564
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr17_-_51224800 0.04 ENSDART00000150089
psen1
presenilin 1
chr22_-_29689485 0.04 ENSDART00000182173
pdcd4b
programmed cell death 4b
chr4_+_26056548 0.04 ENSDART00000171204
SCYL2
si:ch211-244b2.1
chr7_+_24496894 0.04 ENSDART00000149994
nelfa
negative elongation factor complex member A
chr6_-_35738836 0.04 ENSDART00000111642
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr4_+_57099307 0.04 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr20_+_25711718 0.04 ENSDART00000033436
cep135
centrosomal protein 135
chr17_-_19535328 0.04 ENSDART00000077809
cyp26c1
cytochrome P450, family 26, subfamily C, polypeptide 1
chr9_+_3283608 0.04 ENSDART00000192275
hat1
histone acetyltransferase 1
chr3_-_18737126 0.04 ENSDART00000055767
e4f1
E4F transcription factor 1
chr6_-_19023468 0.04 ENSDART00000184729
sept9b
septin 9b
chr10_+_7593185 0.04 ENSDART00000162617
ENSDART00000162590
ENSDART00000171744
ppp2cb
protein phosphatase 2, catalytic subunit, beta isozyme
chr4_+_20566371 0.04 ENSDART00000127576
BX248410.1

chr16_+_9762261 0.04 ENSDART00000020654
psmd4b
proteasome 26S subunit, non-ATPase 4b

Network of associatons between targets according to the STRING database.

First level regulatory network of isl1+isl1l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.3 GO:0097242 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.1 0.3 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.5 GO:0072378 platelet aggregation(GO:0070527) blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.0 0.1 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.2 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.1 GO:0006290 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:0071333 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.0 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.1 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.0 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.2 GO:0044279 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.0 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0032405 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.0 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA