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PRJNA207719: Tissue specific transcriptome profiling

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Results for jun

Z-value: 1.03

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Transcription factors associated with jun

Gene Symbol Gene ID Gene Info
jun
ENSDARG00000043531 Jun proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
jundr11_v1_chr20_+_15552657_15552657-0.837.9e-02Click!

Activity profile of jun motif

Sorted Z-values of jun motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23403602 0.85 ENSDART00000159848
s100w
S100 calcium binding protein W
chr20_+_28364742 0.76 ENSDART00000103355
rhov
ras homolog family member V
chr13_-_33134611 0.74 ENSDART00000026280
plek2
pleckstrin 2
chr7_+_69019851 0.74 ENSDART00000162891
CABZ01057488.1

chr21_+_25765734 0.67 ENSDART00000021664
cldnb
claudin b
chr5_+_45677781 0.61 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr15_+_963292 0.58 ENSDART00000156586
alox5b.2
arachidonate 5-lipoxygenase b, tandem duplicate 2
chr8_+_5024468 0.56 ENSDART00000030938
adra1aa
adrenoceptor alpha 1Aa
chr25_+_18583877 0.53 ENSDART00000148741
met
MET proto-oncogene, receptor tyrosine kinase
chr7_+_14005111 0.51 ENSDART00000187365
furina
furin (paired basic amino acid cleaving enzyme) a
chr8_-_38201415 0.50 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr19_-_7420867 0.49 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr23_+_17522867 0.48 ENSDART00000002714
slc17a9b
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr20_+_26880668 0.47 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_+_48359259 0.47 ENSDART00000167353
sgo1
shugoshin 1
chr13_+_23988442 0.46 ENSDART00000010918
agt
angiotensinogen
chr10_+_28428222 0.45 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr25_+_10410620 0.43 ENSDART00000151886
ehf
ets homologous factor
chr16_-_36834505 0.43 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
pnp4b
purine nucleoside phosphorylase 4b
chr25_-_22191733 0.42 ENSDART00000067478
pkp3a
plakophilin 3a
chr2_+_25839940 0.42 ENSDART00000139927
eif5a2
eukaryotic translation initiation factor 5A2
chr21_+_26612777 0.41 ENSDART00000142667
esrra
estrogen-related receptor alpha
chr1_-_25679339 0.41 ENSDART00000161703
ENSDART00000054230
fgg
fibrinogen gamma chain
chr1_-_25177086 0.40 ENSDART00000144711
ENSDART00000177225
tmem154
transmembrane protein 154
chr1_-_59077650 0.39 ENSDART00000043516
MFAP4 (1 of many)
si:zfos-2330d3.1
chr23_-_1017605 0.39 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr10_+_32050906 0.39 ENSDART00000137373
si:ch211-266i6.3
si:ch211-266i6.3
chr8_+_8671229 0.39 ENSDART00000131963
usp11
ubiquitin specific peptidase 11
chr6_+_56141852 0.38 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr5_+_24089334 0.38 ENSDART00000183748
tp53
tumor protein p53
chr9_+_33216945 0.38 ENSDART00000134029
si:ch211-125e6.12
si:ch211-125e6.12
chr7_+_25033924 0.37 ENSDART00000170873
sb:cb1058
sb:cb1058
chr25_-_13408760 0.37 ENSDART00000154445
gins3
GINS complex subunit 3
chr25_+_29474583 0.37 ENSDART00000191189
il17rel
interleukin 17 receptor E-like
chr10_+_26747755 0.36 ENSDART00000100329
f9b
coagulation factor IXb
chr1_-_58913813 0.36 ENSDART00000056494
zgc:171687
zgc:171687
chr5_-_57480660 0.36 ENSDART00000147875
ENSDART00000142776
si:ch211-202f5.2
si:ch211-202f5.2
chr3_+_32118670 0.36 ENSDART00000055287
ENSDART00000111688
zgc:109934
zgc:109934
chr10_-_3295197 0.35 ENSDART00000109131
slc25a1b
slc25a1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1b
chr9_+_33217243 0.35 ENSDART00000053061
si:ch211-125e6.12
si:ch211-125e6.12
chr22_-_24858042 0.34 ENSDART00000137998
ENSDART00000078216
ENSDART00000138378
vtg7
vitellogenin 7
chr13_+_829585 0.34 ENSDART00000029051
gsta.2
glutathione S-transferase, alpha tandem duplicate 2
chr23_-_1017428 0.33 ENSDART00000110588
ENSDART00000183158
cdh26.1
cadherin 26, tandem duplicate 1
chr23_+_25856541 0.33 ENSDART00000145426
ENSDART00000028236
hnf4a
hepatocyte nuclear factor 4, alpha
chr6_+_51713076 0.33 ENSDART00000146281
ripor3
RIPOR family member 3
chr18_+_47313899 0.33 ENSDART00000192389
ENSDART00000189592
ENSDART00000184281
barx2
BARX homeobox 2
chr17_-_53359028 0.32 ENSDART00000185218
CABZ01068208.1

chr16_-_21785261 0.32 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr10_-_22095505 0.31 ENSDART00000140210
ponzr10
plac8 onzin related protein 10
chr4_+_77948970 0.30 ENSDART00000149636
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr5_+_9037650 0.30 ENSDART00000158226
si:ch211-155m12.1
si:ch211-155m12.1
chr22_+_19218733 0.30 ENSDART00000183212
ENSDART00000133595
si:dkey-21e2.7
si:dkey-21e2.7
chr15_-_46779934 0.30 ENSDART00000085136
clcn2c
chloride channel 2c
chr19_-_5332784 0.29 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr8_-_18667693 0.29 ENSDART00000100516
stap2b
signal transducing adaptor family member 2b
chr18_+_47313715 0.28 ENSDART00000138806
barx2
BARX homeobox 2
chr3_-_26017592 0.28 ENSDART00000030890
hmox1a
heme oxygenase 1a
chr22_-_24297510 0.28 ENSDART00000163297
si:ch211-117l17.6
si:ch211-117l17.6
chr24_-_23839647 0.28 ENSDART00000125190
rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr3_-_48259289 0.28 ENSDART00000160717
znf750
zinc finger protein 750
chr6_-_43449013 0.28 ENSDART00000122423
eevs
2-epi-5-epi-valiolone synthase
chr24_+_30215475 0.28 ENSDART00000164717
si:ch73-358j7.2
si:ch73-358j7.2
chr8_+_6576940 0.28 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr23_-_45398622 0.27 ENSDART00000053571
ENSDART00000149464
zgc:100911
zgc:100911
chr19_-_27570333 0.27 ENSDART00000146562
ENSDART00000179060
si:dkeyp-46h3.5
si:dkeyp-46h3.8
si:dkeyp-46h3.5
si:dkeyp-46h3.8
chr14_+_30774032 0.27 ENSDART00000139552
atl3
atlastin 3
chr16_+_46410520 0.27 ENSDART00000131072
rpz2
rapunzel 2
chr20_+_35445462 0.27 ENSDART00000124497
tdrd6
tudor domain containing 6
chr6_-_49063085 0.27 ENSDART00000156124
si:ch211-105j21.9
si:ch211-105j21.9
chr3_-_26017831 0.27 ENSDART00000179982
hmox1a
heme oxygenase 1a
chr19_-_27564458 0.27 ENSDART00000123155
si:dkeyp-46h3.6
si:dkeyp-46h3.6
chr1_+_54655160 0.27 ENSDART00000190319
si:ch211-202h22.7
si:ch211-202h22.7
chr4_+_16715267 0.26 ENSDART00000143849
pkp2
plakophilin 2
chr7_+_33172066 0.26 ENSDART00000174013
si:ch211-194p6.12
si:ch211-194p6.12
chr23_+_4324625 0.26 ENSDART00000146302
ENSDART00000136792
ENSDART00000135027
ENSDART00000179819
sgk2a
serum/glucocorticoid regulated kinase 2a
chr20_-_26531850 0.26 ENSDART00000183317
ENSDART00000131994
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr20_+_53522059 0.26 ENSDART00000147570
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr3_+_31680592 0.26 ENSDART00000172456
mylk5
myosin, light chain kinase 5
chr22_+_19538626 0.26 ENSDART00000189174
BX936298.2

chr25_-_7753207 0.25 ENSDART00000126499
phf21ab
PHD finger protein 21Ab
chr2_+_38731696 0.25 ENSDART00000181733
FQ377660.1

chr3_+_21189766 0.25 ENSDART00000078807
zgc:123295
zgc:123295
chr3_+_3598555 0.25 ENSDART00000191152
CR589947.3

chr24_-_33366188 0.24 ENSDART00000074161
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr2_-_898899 0.24 ENSDART00000058289
dusp22b
dual specificity phosphatase 22b
chr22_-_5839686 0.24 ENSDART00000145406
si:rp71-36a1.5
si:rp71-36a1.5
chr14_+_30774515 0.24 ENSDART00000191666
atl3
atlastin 3
chr21_+_33459524 0.24 ENSDART00000053205
cd74b
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr11_-_23501467 0.24 ENSDART00000169066
plekha6
pleckstrin homology domain containing, family A member 6
chr4_-_13518381 0.23 ENSDART00000067153
ifng1-1
interferon, gamma 1-1
chr24_+_24726956 0.23 ENSDART00000144574
ENSDART00000066628
mtfr1
mitochondrial fission regulator 1
chr6_-_43028896 0.23 ENSDART00000149977
glyctk
glycerate kinase
chr8_+_39511932 0.22 ENSDART00000113511
lzts1
leucine zipper, putative tumor suppressor 1
chr25_-_12824939 0.22 ENSDART00000169126
uba2
ubiquitin-like modifier activating enzyme 2
chr20_-_26532167 0.22 ENSDART00000061914
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr3_-_3448095 0.22 ENSDART00000078886
A2ML1 (1 of many)
si:dkey-46g23.5
chr8_-_23573084 0.22 ENSDART00000139084
wasb
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr25_+_29474982 0.22 ENSDART00000130410
il17rel
interleukin 17 receptor E-like
chr14_+_1240235 0.22 ENSDART00000127477
adad1
adenosine deaminase domain containing 1 (testis-specific)
chr1_+_59073436 0.22 ENSDART00000161642
MFAP4 (1 of many)
si:zfos-2330d3.3
chr17_-_15600455 0.22 ENSDART00000110272
ENSDART00000156911
si:ch211-266g18.9
si:ch211-266g18.9
chr18_+_6558338 0.22 ENSDART00000110892
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr2_+_25839650 0.22 ENSDART00000134077
ENSDART00000140804
eif5a2
eukaryotic translation initiation factor 5A2
chr5_-_20123002 0.21 ENSDART00000026516
pxmp2
peroxisomal membrane protein 2
chr1_+_57041549 0.21 ENSDART00000152198
si:ch211-1f22.16
si:ch211-1f22.16
chr4_+_9508505 0.21 ENSDART00000080842
kitlgb
kit ligand b
chr2_+_25840463 0.21 ENSDART00000125178
eif5a2
eukaryotic translation initiation factor 5A2
chr15_-_38129845 0.21 ENSDART00000057095
si:dkey-24p1.1
si:dkey-24p1.1
chr16_+_41517188 0.21 ENSDART00000049976
si:dkey-11p23.7
si:dkey-11p23.7
chr20_+_7084154 0.21 ENSDART00000136448
ftr85
finTRIM family, member 85
chr13_-_37649595 0.21 ENSDART00000115354
si:dkey-188i13.10
si:dkey-188i13.10
chr25_+_23336310 0.21 ENSDART00000156457
ptprjb.2
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 2
chr15_+_3766101 0.21 ENSDART00000042580
ENSDART00000112698
ENSDART00000187035
ENSDART00000165571
ENSDART00000121752
RNF14 (1 of many)
zmp:0000000524
chr7_-_8470860 0.20 ENSDART00000172793
loc564481
hypothetical protein LOC564481
chr1_+_59090743 0.20 ENSDART00000100199
mfap4
microfibril associated protein 4
chr1_-_59252973 0.20 ENSDART00000167061
si:ch1073-286c18.5
si:ch1073-286c18.5
chr1_+_59090972 0.20 ENSDART00000171497
mfap4
microfibril associated protein 4
chr9_+_33417969 0.20 ENSDART00000024795
gpr34b
G protein-coupled receptor 34b
chr4_+_25181572 0.20 ENSDART00000078529
ENSDART00000136643
kin
Kin17 DNA and RNA binding protein
chr3_+_46762703 0.20 ENSDART00000133283
prkcsh
protein kinase C substrate 80K-H
chr7_-_71389375 0.20 ENSDART00000128928
CABZ01074298.1

chr2_+_36109002 0.20 ENSDART00000158978
traj28
T-cell receptor alpha joining 28
chr5_+_42141917 0.20 ENSDART00000172201
ENSDART00000140743
trpv1
transient receptor potential cation channel, subfamily V, member 1
chr16_+_49005321 0.20 ENSDART00000160919
CABZ01068499.1

chr20_-_35578435 0.20 ENSDART00000142444
adgrf6
adhesion G protein-coupled receptor F6
chr18_+_15758375 0.20 ENSDART00000137554
si:ch211-219a15.4
si:ch211-219a15.4
chr16_-_40373836 0.19 ENSDART00000134498
si:dkey-242e21.3
si:dkey-242e21.3
chr3_+_22375596 0.19 ENSDART00000188243
ENSDART00000181506
arhgap27l
Rho GTPase activating protein 27, like
chr9_+_8380728 0.19 ENSDART00000133501
si:ch1073-75o15.4
si:ch1073-75o15.4
chr10_-_44560165 0.19 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr22_-_817479 0.19 ENSDART00000123487
zgc:153675
zgc:153675
chr14_-_22100118 0.19 ENSDART00000157547
ssrp1a
structure specific recognition protein 1a
chr8_-_11170114 0.19 ENSDART00000133532
si:ch211-204d2.4
si:ch211-204d2.4
chr13_-_15982707 0.18 ENSDART00000186911
ENSDART00000181072
ikzf1
IKAROS family zinc finger 1 (Ikaros)
chr4_+_77971104 0.18 ENSDART00000188609
zgc:113921
zgc:113921
chr19_+_24575077 0.18 ENSDART00000167469
si:dkeyp-92c9.4
si:dkeyp-92c9.4
chr10_-_44482911 0.18 ENSDART00000085556
hip1ra
huntingtin interacting protein 1 related a
chr6_+_48348415 0.18 ENSDART00000064826
mov10a
Mov10 RISC complex RNA helicase a
chr6_-_12588044 0.18 ENSDART00000047896
slc15a1b
solute carrier family 15 (oligopeptide transporter), member 1b
chr23_-_36316352 0.18 ENSDART00000014840
nfe2
nuclear factor, erythroid 2
chr19_+_15441022 0.17 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr24_-_23998897 0.17 ENSDART00000130053
zmp:0000000991
zmp:0000000991
chr25_-_29072162 0.17 ENSDART00000169269
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr13_-_37122217 0.17 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr2_-_37277626 0.17 ENSDART00000135340
nadkb
NAD kinase b
chr17_+_45413324 0.17 ENSDART00000124911
ezra
ezrin a
chr8_+_32406885 0.17 ENSDART00000167600
epgn
epithelial mitogen homolog (mouse)
chr5_-_1047504 0.17 ENSDART00000159346
mbd2
methyl-CpG binding domain protein 2
chr20_-_25626198 0.17 ENSDART00000126716
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr11_+_37905630 0.16 ENSDART00000170303
si:ch211-112f3.4
si:ch211-112f3.4
chr19_+_7567763 0.16 ENSDART00000140411
s100a11
S100 calcium binding protein A11
chr22_+_19247255 0.16 ENSDART00000144053
si:dkey-21e2.10
si:dkey-21e2.10
chr2_-_985417 0.16 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr21_+_20901505 0.16 ENSDART00000132741
c7b
complement component 7b
chr22_+_1092479 0.16 ENSDART00000170119
guca1e
guanylate cyclase activator 1e
chr24_-_30275204 0.16 ENSDART00000164187
snx7
sorting nexin 7
chr6_+_42475730 0.16 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr3_-_15734358 0.16 ENSDART00000137325
mvp
major vault protein
chr1_+_14253118 0.16 ENSDART00000161996
cxcl8a
chemokine (C-X-C motif) ligand 8a
chr18_+_8320165 0.16 ENSDART00000092053
chkb
choline kinase beta
chr2_+_30379650 0.16 ENSDART00000129542
crispld1b
cysteine-rich secretory protein LCCL domain containing 1b
chr8_+_28695914 0.16 ENSDART00000033386
ocstamp
osteoclast stimulatory transmembrane protein
chr7_+_34786591 0.16 ENSDART00000173700
si:dkey-148a17.5
si:dkey-148a17.5
chr7_+_34549377 0.15 ENSDART00000191814
fhod1
formin homology 2 domain containing 1
chr7_-_3630019 0.15 ENSDART00000138164
ENSDART00000064277
si:dkey-192d15.3
si:dkey-192d15.3
chr22_+_19405517 0.15 ENSDART00000138245
ENSDART00000155144
si:dkey-78l4.2
si:dkey-78l4.2
chr22_+_5532003 0.15 ENSDART00000106174
si:ch73-256j6.2
si:ch73-256j6.2
chr25_-_12824656 0.15 ENSDART00000171801
uba2
ubiquitin-like modifier activating enzyme 2
chr5_+_50953240 0.15 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr2_+_47945359 0.15 ENSDART00000098054
ftr19
finTRIM family, member 19
chr10_+_38775408 0.15 ENSDART00000125045
dscama
Down syndrome cell adhesion molecule a
chr10_+_38775959 0.15 ENSDART00000192990
dscama
Down syndrome cell adhesion molecule a
chr3_+_1179601 0.15 ENSDART00000173378
triobpb
TRIO and F-actin binding protein b
chr4_-_57572054 0.15 ENSDART00000158610
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr22_+_4442473 0.15 ENSDART00000170751
ticam1
toll-like receptor adaptor molecule 1
chr3_-_15734530 0.15 ENSDART00000141142
mvp
major vault protein
chr20_+_9683994 0.15 ENSDART00000053831
ptger2b
prostaglandin E receptor 2b (subtype EP2)
chr19_-_42573219 0.15 ENSDART00000126021
ENSDART00000133695
ENSDART00000131558
zgc:103438
zgc:103438
chr13_+_10621257 0.15 ENSDART00000008603
prepl
prolyl endopeptidase-like
chr8_-_44463985 0.15 ENSDART00000016845
mhc1lba
major histocompatibility complex class I LBA
chr23_+_25232711 0.14 ENSDART00000128510
erbb3b
erb-b2 receptor tyrosine kinase 3b
chr12_+_20587179 0.14 ENSDART00000170127
arsg
arylsulfatase G
chr4_+_77933084 0.14 ENSDART00000148728
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr11_+_24251141 0.14 ENSDART00000182684
pnp4a
purine nucleoside phosphorylase 4a
chr20_+_25625872 0.14 ENSDART00000078385
ppat
phosphoribosyl pyrophosphate amidotransferase
chr22_+_9862243 0.14 ENSDART00000105942
si:dkey-253d23.3
si:dkey-253d23.3
chr15_+_714203 0.14 ENSDART00000153847
si:dkey-7i4.24
si:dkey-7i4.24
chr23_-_4705110 0.14 ENSDART00000144536
ENSDART00000129050
ENSDART00000136399
cnbpa
CCHC-type zinc finger, nucleic acid binding protein a
chr8_-_20243389 0.14 ENSDART00000184904
acer1
alkaline ceramidase 1
chr22_+_19365220 0.14 ENSDART00000132781
ENSDART00000135672
ENSDART00000153630
si:dkey-21e2.12
si:dkey-21e2.12
chr21_+_20903244 0.14 ENSDART00000186193
c7b
complement component 7b
chr20_-_38746889 0.14 ENSDART00000140275
trim54
tripartite motif containing 54
chr19_-_27564980 0.14 ENSDART00000171967
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr4_+_47656992 0.14 ENSDART00000161148
znf1040
zinc finger protein 1040
chr5_-_20195350 0.14 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr6_-_24143923 0.14 ENSDART00000157948
si:ch73-389b16.1
si:ch73-389b16.1
chr5_+_22393501 0.14 ENSDART00000185276
si:dkey-27p18.7
si:dkey-27p18.7
chr5_-_30615901 0.14 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr19_+_15443063 0.14 ENSDART00000151732
lin28a
lin-28 homolog A (C. elegans)
chr3_+_19687217 0.14 ENSDART00000141937
tlk2
tousled-like kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of jun

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 0.6 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.1 0.4 GO:0043525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.8 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.5 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.4 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.6 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.1 0.2 GO:0010934 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081) myeloid leukocyte cytokine production(GO:0061082)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.2 GO:0002676 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.2 GO:0048940 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.0 0.6 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.5 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.4 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.5 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.5 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.1 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.5 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0 0.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.4 GO:0072378 platelet aggregation(GO:0070527) blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:1905208 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.4 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.6 GO:0051180 vitamin transport(GO:0051180)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0007620 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.1 GO:0060343 trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)
0.0 0.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.6 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0032355 response to estradiol(GO:0032355)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.0 0.2 GO:0030428 cell septum(GO:0030428)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.6 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 0.6 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 0.2 GO:0008887 glycerate kinase activity(GO:0008887)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.2 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.0 0.2 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.0 0.2 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.2 GO:0010853 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.0 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE