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PRJNA207719: Tissue specific transcriptome profiling

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Results for lhx2b+lhx9

Z-value: 0.46

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Transcription factors associated with lhx2b+lhx9

Gene Symbol Gene ID Gene Info
lhx2b
ENSDARG00000031222 LIM homeobox 2b
lhx9
ENSDARG00000056979 LIM homeobox 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx9dr11_v1_chr22_-_23253481_23253481-0.672.2e-01Click!
lhx2bdr11_v1_chr8_+_3085120_3085219-0.573.2e-01Click!

Activity profile of lhx2b+lhx9 motif

Sorted Z-values of lhx2b+lhx9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_63302944 0.47 ENSDART00000047110
gsnb
gelsolin b
chr25_-_21031007 0.46 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr9_-_9415000 0.38 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr12_+_37401331 0.37 ENSDART00000125040
si:ch211-152f22.4
si:ch211-152f22.4
chr21_+_25236297 0.36 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr14_+_901847 0.29 ENSDART00000166991
si:ch73-208h1.2
si:ch73-208h1.2
chr23_-_33350990 0.28 ENSDART00000144831
si:ch211-226m16.2
si:ch211-226m16.2
chr19_+_2631565 0.28 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr8_-_25771474 0.28 ENSDART00000193883
suv39h1b
suppressor of variegation 3-9 homolog 1b
chr10_+_2742499 0.28 ENSDART00000122847
grk5
G protein-coupled receptor kinase 5
chr19_+_43297546 0.28 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr20_+_28364742 0.27 ENSDART00000103355
rhov
ras homolog family member V
chr2_-_36918709 0.27 ENSDART00000084876
zgc:153654
zgc:153654
chr12_-_4243268 0.27 ENSDART00000131275
zgc:92313
zgc:92313
chr21_+_25777425 0.26 ENSDART00000021620
cldnd
claudin d
chr3_+_13559199 0.26 ENSDART00000166547
si:ch73-106n3.1
si:ch73-106n3.1
chr14_-_4145594 0.25 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr6_-_35046735 0.25 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr23_+_36460239 0.24 ENSDART00000172441
lima1a
LIM domain and actin binding 1a
chr12_-_35830625 0.24 ENSDART00000180028
CU459056.1

chr8_+_34731982 0.23 ENSDART00000066050
hpdb
4-hydroxyphenylpyruvate dioxygenase b
chr1_+_9966384 0.22 ENSDART00000132607
si:dkeyp-75b4.8
si:dkeyp-75b4.8
chr6_+_39905021 0.22 ENSDART00000064904
endou
endonuclease, polyU-specific
chr22_-_10156581 0.20 ENSDART00000168304
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr19_+_7895086 0.20 ENSDART00000132180
si:dkey-266f7.1
si:dkey-266f7.1
chr20_-_35750810 0.20 ENSDART00000153072
adgrf8
adhesion G protein-coupled receptor F8
chr9_+_21165484 0.20 ENSDART00000177286
si:rp71-68n21.9
si:rp71-68n21.9
chr8_-_20230559 0.19 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr7_-_54320088 0.19 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr13_+_7442023 0.19 ENSDART00000080975
tnfaip2b
tumor necrosis factor, alpha-induced protein 2b
chr10_+_17776981 0.19 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr14_+_15257658 0.19 ENSDART00000161625
ENSDART00000193577
si:dkey-77g12.4
si:dkey-203a12.5
si:dkey-77g12.4
si:dkey-203a12.5
chr11_+_705727 0.19 ENSDART00000165366
timp4.2
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr19_+_43780970 0.19 ENSDART00000063870
rpl11
ribosomal protein L11
chr3_+_29941777 0.19 ENSDART00000113889
ifi35
interferon-induced protein 35
chr25_+_3217419 0.19 ENSDART00000104859
rccd1
RCC1 domain containing 1
chr4_+_77943184 0.18 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr23_-_16485190 0.18 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr22_+_5687615 0.18 ENSDART00000133241
ENSDART00000019854
ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr4_-_71904377 0.18 ENSDART00000191852
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr22_+_19366866 0.17 ENSDART00000137301
si:dkey-21e2.12
si:dkey-21e2.12
chr10_-_34002185 0.17 ENSDART00000046599
zar1l
zygote arrest 1-like
chr5_+_27897504 0.17 ENSDART00000130936
adam28
ADAM metallopeptidase domain 28
chr4_-_9891874 0.16 ENSDART00000067193
adm2a
adrenomedullin 2a
chr4_+_53119675 0.16 ENSDART00000167470
si:dkey-8o9.2
si:dkey-8o9.2
chr22_+_5532003 0.16 ENSDART00000106174
si:ch73-256j6.2
si:ch73-256j6.2
chr21_-_44081540 0.16 ENSDART00000130833
FO704810.1

chr5_-_30620625 0.16 ENSDART00000098273
tcnl
transcobalamin like
chr9_-_30555725 0.16 ENSDART00000079222
chaf1b
chromatin assembly factor 1, subunit B
chr12_-_18578432 0.16 ENSDART00000122858
zdhhc4
zinc finger, DHHC-type containing 4
chr6_-_43677125 0.16 ENSDART00000150128
foxp1b
forkhead box P1b
chr23_+_4709607 0.16 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr25_+_8356707 0.15 ENSDART00000153708
muc5.1
mucin 5.1, oligomeric mucus/gel-forming
chr17_-_27048537 0.15 ENSDART00000050018
ENSDART00000193861
cnksr1
connector enhancer of kinase suppressor of Ras 1
chr5_-_30715225 0.15 ENSDART00000016758
ftr82
finTRIM family, member 82
chr5_-_57723929 0.15 ENSDART00000144237
gig2p
grass carp reovirus (GCRV)-induced gene 2p
chr20_+_25586099 0.15 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr5_+_27898226 0.15 ENSDART00000098604
ENSDART00000180251
adam28
ADAM metallopeptidase domain 28
chr3_-_59297532 0.15 ENSDART00000187991
CABZ01053748.1

chr2_+_36112273 0.14 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr23_-_36446307 0.14 ENSDART00000136623
zgc:174906
zgc:174906
chr24_-_26622423 0.14 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr10_+_36650222 0.14 ENSDART00000126963
ucp3
uncoupling protein 3
chr10_+_29850330 0.13 ENSDART00000168898
hspa8
heat shock protein 8
chr8_-_21091961 0.13 ENSDART00000100281
aldh9a1a.2
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2
chr22_+_508290 0.13 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr5_+_2815021 0.13 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr25_+_11008419 0.13 ENSDART00000156589
mhc1lia
major histocompatibility complex class I LIA
chr3_-_50443607 0.13 ENSDART00000074036
rcvrna
recoverin a
chr3_+_26145013 0.13 ENSDART00000162546
ENSDART00000129561
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr18_-_8877077 0.13 ENSDART00000137266
si:dkey-95h12.2
si:dkey-95h12.2
chr4_-_42408339 0.12 ENSDART00000172612
si:ch211-59d8.3
si:ch211-59d8.3
chr22_+_16535575 0.12 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr17_+_8799661 0.12 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr14_+_32430982 0.12 ENSDART00000017179
ENSDART00000123382
ENSDART00000075593
f9a
coagulation factor IXa
chr12_+_20641102 0.12 ENSDART00000152964
calcoco2
calcium binding and coiled-coil domain 2
chr25_+_29474982 0.12 ENSDART00000130410
il17rel
interleukin 17 receptor E-like
chr12_+_20641471 0.12 ENSDART00000133654
calcoco2
calcium binding and coiled-coil domain 2
chr20_-_43663494 0.12 ENSDART00000144564
BX470188.1

chr14_-_7207961 0.12 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr14_-_14659023 0.12 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr23_-_1660708 0.12 ENSDART00000175138
CU693481.1

chr2_+_9990491 0.12 ENSDART00000011906
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr8_-_20230802 0.12 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr2_+_105748 0.12 ENSDART00000169601
CABZ01098670.1

chr4_+_966061 0.12 ENSDART00000122535
rpap3
RNA polymerase II associated protein 3
chr9_-_43644261 0.12 ENSDART00000023684
cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr7_-_50410524 0.12 ENSDART00000083346
hypk
huntingtin interacting protein K
chr23_-_29394505 0.11 ENSDART00000017728
pgd
phosphogluconate dehydrogenase
chr3_-_32079916 0.11 ENSDART00000040900
baxb
BCL2 associated X, apoptosis regulator b
chr24_-_32582880 0.11 ENSDART00000186307
rdh12l
retinol dehydrogenase 12, like
chr15_-_43284021 0.11 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr15_-_39969988 0.11 ENSDART00000146054
rps5
ribosomal protein S5
chr21_-_26114886 0.11 ENSDART00000139320
nipal4
NIPA-like domain containing 4
chr23_-_30041065 0.11 ENSDART00000131209
ENSDART00000127192
ccdc187
coiled-coil domain containing 187
chr23_-_36303216 0.11 ENSDART00000188720
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr8_+_11425048 0.11 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr25_+_22320738 0.11 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr8_+_17167876 0.10 ENSDART00000134665
cenph
centromere protein H
chr6_+_612594 0.10 ENSDART00000150903
kynu
kynureninase
chr17_-_23616626 0.10 ENSDART00000104730
ifit14
interferon-induced protein with tetratricopeptide repeats 14
chr2_-_10877765 0.10 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr23_+_384850 0.10 ENSDART00000114000
zgc:101663
zgc:101663
chr3_-_29941357 0.10 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
grna
granulin a
chr1_+_44127292 0.10 ENSDART00000160542
cabp2a
calcium binding protein 2a
chr8_-_30204650 0.10 ENSDART00000133209
zgc:162939
zgc:162939
chr16_-_11798994 0.10 ENSDART00000135408
cnfn
cornifelin
chr17_+_8799451 0.10 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr12_-_18578218 0.10 ENSDART00000125803
zdhhc4
zinc finger, DHHC-type containing 4
chr13_-_31008275 0.10 ENSDART00000139394
wdfy4
WDFY family member 4
chr5_+_13647288 0.09 ENSDART00000099660
ENSDART00000139199
h2afva
H2A histone family, member Va
chr20_+_25225112 0.09 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
moxd1
monooxygenase, DBH-like 1
chr19_+_12237945 0.09 ENSDART00000190034
grhl2b
grainyhead-like transcription factor 2b
chr7_-_3836896 0.09 ENSDART00000136227
si:dkey-88n24.8
si:dkey-88n24.8
chr7_-_3836635 0.09 ENSDART00000104350
si:dkey-88n24.8
si:dkey-88n24.8
chr10_+_11261576 0.09 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr2_+_48073972 0.09 ENSDART00000186442
klf6b
Kruppel-like factor 6b
chr15_-_38129845 0.09 ENSDART00000057095
si:dkey-24p1.1
si:dkey-24p1.1
chr6_-_39270851 0.09 ENSDART00000148839
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr2_-_9989919 0.09 ENSDART00000180213
ENSDART00000184369
imp3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr3_-_31079186 0.09 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr1_+_51721851 0.09 ENSDART00000040397
prdx2
peroxiredoxin 2
chr1_-_55118745 0.09 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr22_+_7738966 0.09 ENSDART00000147073
si:ch73-44m9.5
si:ch73-44m9.5
chr8_+_28695914 0.09 ENSDART00000033386
ocstamp
osteoclast stimulatory transmembrane protein
chr4_-_62714083 0.09 ENSDART00000188299
si:dkey-28k24.2
si:dkey-28k24.2
chr20_+_48116476 0.09 ENSDART00000043938
tram2
translocation associated membrane protein 2
chr21_-_1644414 0.08 ENSDART00000105736
ENSDART00000124904
zgc:152948
zgc:152948
chr17_-_20558961 0.08 ENSDART00000155993
sh3pxd2ab
SH3 and PX domains 2Ab
chr3_-_10739625 0.08 ENSDART00000156144
zgc:112965
zgc:112965
chr7_+_71664624 0.08 ENSDART00000170273
emilin2b
elastin microfibril interfacer 2b
chr23_+_11347313 0.08 ENSDART00000135406
chl1a
cell adhesion molecule L1-like a
chr3_-_15999501 0.08 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr9_+_23895711 0.08 ENSDART00000034686
cops8
COP9 signalosome subunit 8
chr5_+_38752287 0.08 ENSDART00000133571
cxcl11.8
chemokine (C-X-C motif) ligand 11, duplicate 8
chr3_-_53114299 0.08 ENSDART00000109390
AL954361.1

chr2_+_20406399 0.08 ENSDART00000006817
ENSDART00000137848
palmda
palmdelphin a
chr5_-_11809710 0.08 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr23_-_42232124 0.08 ENSDART00000149944
gpx7
glutathione peroxidase 7
chr24_+_2495197 0.08 ENSDART00000146887
f13a1a.1
coagulation factor XIII, A1 polypeptide a, tandem duplicate 1
chr11_+_42474694 0.08 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
si:ch1073-165f9.2
chr3_-_57666518 0.08 ENSDART00000102062
timp2b
TIMP metallopeptidase inhibitor 2b
chr3_-_32818607 0.07 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr5_-_66823750 0.07 ENSDART00000041441
ENSDART00000112488
stip1
stress-induced phosphoprotein 1
chr19_+_14573998 0.07 ENSDART00000022076
fam46bb
family with sequence similarity 46, member Bb
chr22_+_37631234 0.07 ENSDART00000007346
psmd1
proteasome 26S subunit, non-ATPase 1
chr1_+_47499888 0.07 ENSDART00000027624
stn1
STN1, CST complex subunit
chr6_+_8598428 0.07 ENSDART00000032118
ube2g2
ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)
chr22_-_9183944 0.07 ENSDART00000188599
si:ch211-213a13.5
si:ch211-213a13.5
chr22_+_737211 0.07 ENSDART00000017305
znf76
zinc finger protein 76
chr6_+_12527725 0.07 ENSDART00000149328
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr16_+_54209504 0.07 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr19_+_43359075 0.07 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr10_+_44373349 0.07 ENSDART00000172191
snrnp35
small nuclear ribonucleoprotein 35 (U11/U12)
chr13_+_33268657 0.07 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr19_-_41518922 0.07 ENSDART00000164483
ENSDART00000062080
chrac1
chromatin accessibility complex 1
chr13_-_42560662 0.07 ENSDART00000124898
CR792417.1

chr15_-_40157165 0.07 ENSDART00000192991
si:ch211-281l24.3
si:ch211-281l24.3
chr10_-_31015535 0.07 ENSDART00000146116
panx3
pannexin 3
chr7_-_8738827 0.07 ENSDART00000172807
ENSDART00000173026
si:ch211-1o7.3
si:ch211-1o7.3
chr4_-_67980261 0.07 ENSDART00000182305
si:ch211-223k15.1
si:ch211-223k15.1
chr2_-_7845110 0.07 ENSDART00000091987
si:ch211-38m6.7
si:ch211-38m6.7
chr15_-_40157331 0.06 ENSDART00000187958
si:ch211-281l24.3
si:ch211-281l24.3
chr25_+_28825657 0.06 ENSDART00000153625
nfybb
nuclear transcription factor Y, beta b
chr12_-_18577983 0.06 ENSDART00000193262
zdhhc4
zinc finger, DHHC-type containing 4
chr19_+_1688727 0.06 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr25_-_18739924 0.06 ENSDART00000156328
si:dkeyp-93a5.2
si:dkeyp-93a5.2
chr7_-_67248829 0.06 ENSDART00000192442
znf143a
zinc finger protein 143a
chr16_+_24733741 0.06 ENSDART00000155217
si:dkey-79d12.4
si:dkey-79d12.4
chr4_+_5255041 0.06 ENSDART00000137966
ccdc167
coiled-coil domain containing 167
chr20_+_5985329 0.06 ENSDART00000165489
cep128
centrosomal protein 128
chr16_+_28994709 0.06 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr7_+_57088920 0.06 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr2_+_44571200 0.06 ENSDART00000098132
klhl24a
kelch-like family member 24a
chr12_-_28363111 0.06 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr13_+_18321140 0.06 ENSDART00000180947
eif4e1c
eukaryotic translation initiation factor 4E family member 1c
chr21_+_11885404 0.06 ENSDART00000092015
dcaf12
DDB1 and CUL4 associated factor 12
chr20_-_49889111 0.06 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr23_+_16815353 0.06 ENSDART00000142789
ENSDART00000143424
zgc:100832
zgc:100832
chr9_+_37152564 0.06 ENSDART00000189497
gli2a
GLI family zinc finger 2a
chr3_+_23029934 0.05 ENSDART00000110343
nags
N-acetylglutamate synthase
chr8_+_45334255 0.05 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr20_-_51355465 0.05 ENSDART00000151620
ENSDART00000151690
ENSDART00000110289
tcte1
t-complex-associated-testis-expressed 1
chr12_+_20587179 0.05 ENSDART00000170127
arsg
arylsulfatase G
chr15_-_40157513 0.05 ENSDART00000184014
si:ch211-281l24.3
si:ch211-281l24.3
chr15_+_21262917 0.05 ENSDART00000101000
gkup
glucuronokinase with putative uridyl pyrophosphorylase
chr10_-_42923385 0.05 ENSDART00000076731
ACOT12
acyl-CoA thioesterase 12
chr8_-_12867128 0.05 ENSDART00000142201
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr8_+_28259347 0.05 ENSDART00000110857
fam212b
family with sequence similarity 212, member B
chr23_-_18567088 0.05 ENSDART00000192371
sephs2
selenophosphate synthetase 2
chr1_-_55248496 0.05 ENSDART00000098615
nanos3
nanos homolog 3
chr24_-_7995960 0.05 ENSDART00000186594
bloc1s5
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr2_-_7843451 0.05 ENSDART00000163265
si:ch211-38m6.7
si:ch211-38m6.7
chr22_+_37631034 0.05 ENSDART00000159016
ENSDART00000193346
psmd1
proteasome 26S subunit, non-ATPase 1
chr5_+_1624359 0.05 ENSDART00000165431
PPP1CC
protein phosphatase 1 catalytic subunit gamma
chr8_+_52637507 0.05 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr22_+_1708760 0.05 ENSDART00000170471
si:dkey-1b17.9
si:dkey-1b17.9
chr10_-_43771447 0.05 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr5_-_23843636 0.05 ENSDART00000193280
GBGT1 (1 of many)
si:ch211-135f11.5
chr14_+_46313396 0.05 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx2b+lhx9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.0 0.1 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.1 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0042421 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.3 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.1 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.2 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.0 0.2 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.5 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols