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PRJNA207719: Tissue specific transcriptome profiling

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Results for lhx6-1

Z-value: 0.80

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Transcription factors associated with lhx6-1

Gene Symbol Gene ID Gene Info
lhx6-1
ENSDARG00000052165 si_ch211-236k19.2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:ch211-236k19.2dr11_v1_chr5_-_64900552_64900552-0.247.0e-01Click!

Activity profile of lhx6-1 motif

Sorted Z-values of lhx6-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_6751405 0.59 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr21_+_6751760 0.47 ENSDART00000135914
olfm1b
olfactomedin 1b
chr25_+_3327071 0.46 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr25_+_3326885 0.41 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr13_-_4707018 0.34 ENSDART00000128422
oit3
oncoprotein induced transcript 3
chr8_-_45277370 0.33 ENSDART00000146364
adamts13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr2_+_6255434 0.31 ENSDART00000139429
zp3b
zona pellucida glycoprotein 3b
chr16_-_28658341 0.30 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr10_+_7709724 0.29 ENSDART00000097670
ggcx
gamma-glutamyl carboxylase
chr19_+_9295244 0.27 ENSDART00000132255
ENSDART00000144299
si:ch73-15n24.1
si:ch73-15n24.1
chr22_-_22719440 0.27 ENSDART00000166794
nr5a2
nuclear receptor subfamily 5, group A, member 2
chr7_+_30392613 0.26 ENSDART00000075508
lipca
lipase, hepatic a
chr3_-_26017831 0.25 ENSDART00000179982
hmox1a
heme oxygenase 1a
chr3_-_23407720 0.23 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr15_+_45563656 0.22 ENSDART00000157501
cldn15lb
claudin 15-like b
chr2_-_38284648 0.22 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
si:ch211-14a17.7
chr2_+_6253246 0.22 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr12_+_47446158 0.22 ENSDART00000152857
fmn2b
formin 2b
chr11_+_5588122 0.22 ENSDART00000113281
zgc:172302
zgc:172302
chr23_-_41651759 0.22 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr16_+_23975930 0.21 ENSDART00000147858
ENSDART00000144347
ENSDART00000115270
apoc4
apolipoprotein C-IV
chr1_+_29068654 0.21 ENSDART00000053932
cbsa
cystathionine-beta-synthase a
chr9_+_44994214 0.21 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr17_+_30704068 0.20 ENSDART00000062793
apoba
apolipoprotein Ba
chr24_-_9979342 0.20 ENSDART00000138576
ENSDART00000191206
zgc:171977
zgc:171977
chr19_-_5805923 0.19 ENSDART00000134340
si:ch211-264f5.8
si:ch211-264f5.8
chr4_+_11375894 0.19 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr16_+_23976227 0.18 ENSDART00000193013
apoc4
apolipoprotein C-IV
chr15_+_44366556 0.18 ENSDART00000133449
GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2
chr2_+_50608099 0.17 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr19_-_9882821 0.17 ENSDART00000147128
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr12_-_22238004 0.17 ENSDART00000038310
ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr10_+_34001444 0.17 ENSDART00000149934
kl
klotho
chr23_-_30787932 0.17 ENSDART00000135771
myt1a
myelin transcription factor 1a
chr6_+_57541776 0.17 ENSDART00000157330
necab3
N-terminal EF-hand calcium binding protein 3
chr13_+_771403 0.17 ENSDART00000093166
nrxn1b
neurexin 1b
chr9_+_219124 0.16 ENSDART00000161484
map3k12
mitogen-activated protein kinase kinase kinase 12
chr16_+_47207691 0.16 ENSDART00000062507
ica1
islet cell autoantigen 1
chr5_+_22098591 0.16 ENSDART00000143676
zc3h12b
zinc finger CCCH-type containing 12B
chr14_-_14659023 0.16 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr10_-_34915886 0.15 ENSDART00000141201
ENSDART00000002166
ccna1
cyclin A1
chr6_+_27151940 0.15 ENSDART00000088364
kif1aa
kinesin family member 1Aa
chr3_+_46559639 0.15 ENSDART00000146189
ENSDART00000127832
ENSDART00000151035
raver1
ribonucleoprotein, PTB-binding 1
chr17_-_37214196 0.15 ENSDART00000128715
kif3cb
kinesin family member 3Cb
chr3_+_33345348 0.15 ENSDART00000059262
mpp2a
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr25_+_21324588 0.15 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr24_-_33366188 0.14 ENSDART00000074161
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr6_+_25261297 0.14 ENSDART00000162824
ENSDART00000163490
ENSDART00000157790
ENSDART00000160978
ENSDART00000161545
ENSDART00000159978
kyat3
kynurenine aminotransferase 3
chr20_+_23947004 0.14 ENSDART00000144195
casp8ap2
caspase 8 associated protein 2
chr13_-_25198025 0.14 ENSDART00000159585
ENSDART00000144227
adka
adenosine kinase a
chr13_+_8954667 0.13 ENSDART00000100241
haao
3-hydroxyanthranilate 3,4-dioxygenase
chr10_+_16188761 0.13 ENSDART00000193244
ctxn3
cortexin 3
chr12_+_1469090 0.13 ENSDART00000183637
usp22
ubiquitin specific peptidase 22
chr18_+_38908903 0.13 ENSDART00000159834
myo5aa
myosin VAa
chr6_+_34511886 0.13 ENSDART00000179450
lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr1_+_19708508 0.13 ENSDART00000054581
ENSDART00000131206
march1
membrane-associated ring finger (C3HC4) 1
chr7_+_69528850 0.12 ENSDART00000109507
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1
chr4_-_28158335 0.12 ENSDART00000134605
gramd4a
GRAM domain containing 4a
chr16_+_39159752 0.12 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr24_-_25004553 0.12 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr23_+_28582865 0.12 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr25_+_13498188 0.12 ENSDART00000015710
snrkb
SNF related kinase b
chr5_-_62306819 0.12 ENSDART00000168993
spata22
spermatogenesis associated 22
chr18_+_21408794 0.12 ENSDART00000140161
necab2
N-terminal EF-hand calcium binding protein 2
chr3_-_25275364 0.12 ENSDART00000163782
ENSDART00000145420
ENSDART00000133718
ENSDART00000055492
ddx5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr22_-_16180467 0.12 ENSDART00000171331
ENSDART00000185607
vcam1b
vascular cell adhesion molecule 1b
chr19_-_5103313 0.11 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr5_-_67629263 0.11 ENSDART00000133753
zbtb20
zinc finger and BTB domain containing 20
chr3_-_6519691 0.11 ENSDART00000165273
ENSDART00000179882
ENSDART00000172292
GGA3 (1 of many)
si:ch73-157i16.3
chr10_+_15777064 0.11 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr2_+_56937548 0.11 ENSDART00000189308
CABZ01117752.1

chr15_-_22074315 0.11 ENSDART00000149830
drd2a
dopamine receptor D2a
chr1_-_46981134 0.11 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr23_+_4646194 0.11 ENSDART00000092344
LO017700.1

chr25_-_1323623 0.11 ENSDART00000156532
ENSDART00000157163
ENSDART00000156062
ENSDART00000082447
ENSDART00000189175
calml4b
calmodulin-like 4b
chr15_-_9593532 0.11 ENSDART00000169912
gab2
GRB2-associated binding protein 2
chr4_+_9467049 0.11 ENSDART00000012659
zgc:55888
zgc:55888
chr1_+_30723677 0.11 ENSDART00000177900
bora
bora, aurora kinase A activator
chr17_-_200316 0.11 ENSDART00000190561
CABZ01083778.1

chr18_+_11506561 0.11 ENSDART00000121647
PRMT8
protein arginine methyltransferase 8
chr6_+_40951227 0.11 ENSDART00000156660
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr2_-_3038904 0.11 ENSDART00000186795
guk1a
guanylate kinase 1a
chr25_+_26921480 0.11 ENSDART00000155949
grm8b
glutamate receptor, metabotropic 8b
chr22_-_20011476 0.11 ENSDART00000093312
ENSDART00000093310
celf5a
cugbp, Elav-like family member 5a
chr8_+_49975160 0.11 ENSDART00000156403
ENSDART00000080135
gfpt1
glutamine--fructose-6-phosphate transaminase 1
chr5_-_12407194 0.10 ENSDART00000125291
ksr2
kinase suppressor of ras 2
chr21_-_39177564 0.10 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr11_+_38280454 0.10 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr21_+_43404945 0.10 ENSDART00000142234
frmd7
FERM domain containing 7
chr22_-_7050 0.10 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr5_+_64842730 0.10 ENSDART00000144732
lrrc8ab
leucine rich repeat containing 8 VRAC subunit Ab
chr22_-_29083070 0.10 ENSDART00000104812
ENSDART00000172576
cbx6a
chromobox homolog 6a
chr7_+_30787903 0.10 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr5_+_20257225 0.10 ENSDART00000127919
ssh1a
slingshot protein phosphatase 1a
chr16_-_29437373 0.10 ENSDART00000148405
si:ch211-113g11.6
si:ch211-113g11.6
chr9_-_12886108 0.10 ENSDART00000177283
ankzf1
ankyrin repeat and zinc finger domain containing 1
chr10_+_44584614 0.10 ENSDART00000163523
sez6l
seizure related 6 homolog (mouse)-like
chr2_+_56168619 0.10 ENSDART00000021011
ENSDART00000180271
upf1
upf1 regulator of nonsense transcripts homolog (yeast)
chr19_+_5604241 0.09 ENSDART00000011025
wipf2b
WAS/WASL interacting protein family, member 2b
chr17_+_1063988 0.09 ENSDART00000160400
gchfr
GTP cyclohydrolase I feedback regulator
chr12_-_42214 0.09 ENSDART00000045071
foxk2
forkhead box K2
chr3_-_46817499 0.09 ENSDART00000013717
elavl3
ELAV like neuron-specific RNA binding protein 3
chr11_-_41130239 0.09 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr24_-_18809433 0.09 ENSDART00000152009
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr4_+_77957611 0.09 ENSDART00000156692
arfgap3
ADP-ribosylation factor GTPase activating protein 3
chr14_-_47815467 0.09 ENSDART00000166827
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr16_-_40841363 0.09 ENSDART00000163380
si:dkey-22o22.2
si:dkey-22o22.2
chr9_-_10460087 0.09 ENSDART00000186001
thsd7ba
thrombospondin, type I, domain containing 7Ba
chr3_-_30625219 0.09 ENSDART00000151698
syt3
synaptotagmin III
chr3_-_23406964 0.09 ENSDART00000114723
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr2_-_15031858 0.09 ENSDART00000191478
hccsa.1
holocytochrome c synthase a
chr10_-_34916208 0.09 ENSDART00000187371
ccna1
cyclin A1
chr5_+_42388464 0.09 ENSDART00000191596
BX548073.13

chr1_+_33668236 0.09 ENSDART00000122316
ENSDART00000102184
arl13b
ADP-ribosylation factor-like 13b
chr8_-_23780334 0.09 ENSDART00000145179
ENSDART00000145894
zgc:195245
zgc:195245
chr17_+_8212477 0.09 ENSDART00000064665
slc18b1
solute carrier family 18, subfamily B, member 1
chr4_-_9191220 0.09 ENSDART00000156919
hcfc2
host cell factor C2
chr21_+_26390549 0.08 ENSDART00000185643
tmsb
thymosin, beta
chr5_-_27993972 0.08 ENSDART00000175819
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr5_-_64831207 0.08 ENSDART00000144816
lix1
limb and CNS expressed 1
chr8_-_16464453 0.08 ENSDART00000098691
rnf11b
ring finger protein 11b
chr13_+_2442841 0.08 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
arfgef3
ARFGEF family member 3
chr11_-_15296805 0.08 ENSDART00000124968
rpn2
ribophorin II
chr7_+_49272702 0.08 ENSDART00000083389
abtb2a
ankyrin repeat and BTB (POZ) domain containing 2a
chr9_+_17983463 0.08 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr4_-_23873924 0.08 ENSDART00000100391
usp6nl
USP6 N-terminal like
chr22_-_21897203 0.08 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr8_-_39822917 0.08 ENSDART00000067843
zgc:162025
zgc:162025
chr20_-_47188966 0.08 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr11_+_45323455 0.08 ENSDART00000189249
mafgb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr19_+_20274264 0.08 ENSDART00000183513
oxnad1
oxidoreductase NAD-binding domain containing 1
chr12_-_3940768 0.08 ENSDART00000134292
zgc:92040
zgc:92040
chr19_-_20430892 0.08 ENSDART00000111409
tbc1d5
TBC1 domain family, member 5
chr7_+_54642005 0.08 ENSDART00000171864
fgf19
fibroblast growth factor 19
chr24_-_31843173 0.08 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr13_+_24584401 0.08 ENSDART00000057599
fuom
fucose mutarotase
chr4_+_21129752 0.08 ENSDART00000169764
syt1a
synaptotagmin Ia
chr19_+_20274491 0.07 ENSDART00000090860
ENSDART00000151693
oxnad1
oxidoreductase NAD-binding domain containing 1
chr3_-_60827402 0.07 ENSDART00000053494
anks4b
ankyrin repeat and sterile alpha motif domain containing 4B
chr4_-_29753895 0.07 ENSDART00000150742
si:dkey-191j3.1
si:dkey-191j3.1
chr11_-_16021424 0.07 ENSDART00000193291
ENSDART00000170731
ENSDART00000104107
zgc:173544
zgc:173544
chr4_+_11384891 0.07 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr5_+_25733774 0.07 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr1_+_30723380 0.07 ENSDART00000127943
ENSDART00000062628
ENSDART00000127670
bora
bora, aurora kinase A activator
chr7_+_7151832 0.07 ENSDART00000109485
gal3st3
galactose-3-O-sulfotransferase 3
chr25_+_459901 0.07 ENSDART00000154895
prtgb
protogenin homolog b (Gallus gallus)
chr24_-_24724233 0.07 ENSDART00000127044
ENSDART00000012399
armc1
armadillo repeat containing 1
chr4_-_73756673 0.07 ENSDART00000174274
ENSDART00000192913
ENSDART00000113546
BX855614.4
si:dkey-262g12.14
zgc:171551

si:dkey-262g12.14
zgc:171551
chr5_+_42381273 0.07 ENSDART00000142387
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr19_-_1871415 0.07 ENSDART00000004585
clptm1l
CLPTM1-like
chr5_-_25733745 0.07 ENSDART00000051566
zgc:101016
zgc:101016
chr18_-_7112882 0.07 ENSDART00000176292
si:dkey-88e18.8
si:dkey-88e18.8
chr23_-_33038423 0.07 ENSDART00000180539
plxna2
plexin A2
chr8_+_8947623 0.07 ENSDART00000131215
slc35a2
solute carrier family 35 (UDP-galactose transporter), member 2
chr23_-_4225606 0.06 ENSDART00000014152
ENSDART00000133341
aar2
AAR2 splicing factor homolog (S. cerevisiae)
chr3_+_32365811 0.06 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr20_-_29532939 0.06 ENSDART00000049224
ENSDART00000062377
taf1b
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr1_-_29139141 0.06 ENSDART00000075546
ENSDART00000133246
hsf2bp
heat shock transcription factor 2 binding protein
chr10_-_105100 0.06 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr8_-_15129573 0.06 ENSDART00000142358
bcar3
BCAR3, NSP family adaptor protein
chr20_-_13774826 0.06 ENSDART00000063831
opn8c
opsin 8, group member c
chr16_-_25568512 0.06 ENSDART00000149411
atxn1b
ataxin 1b
chr19_-_46088429 0.06 ENSDART00000161385
ptdss1b
phosphatidylserine synthase 1b
chr24_+_9178064 0.06 ENSDART00000142971
dlgap1b
discs, large (Drosophila) homolog-associated protein 1b
chr13_-_10730056 0.06 ENSDART00000126725
ppm1ba
protein phosphatase, Mg2+/Mn2+ dependent, 1Ba
chr21_-_40398932 0.06 ENSDART00000162500
nup98
nucleoporin 98
chr6_-_40922971 0.06 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr22_-_33679277 0.06 ENSDART00000169948
FO904977.1

chr17_-_37195354 0.06 ENSDART00000190963
asxl2
additional sex combs like transcriptional regulator 2
chr2_-_55298075 0.05 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr17_-_37195163 0.05 ENSDART00000108514
asxl2
additional sex combs like transcriptional regulator 2
chr2_-_21621878 0.05 ENSDART00000189540
zgc:55781
zgc:55781
chr24_+_1023839 0.05 ENSDART00000082526
zgc:111976
zgc:111976
chr4_+_9400012 0.05 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr11_+_2855430 0.05 ENSDART00000172837
kif21b
kinesin family member 21B
chr14_-_12020653 0.05 ENSDART00000106654
znf711
zinc finger protein 711
chr12_+_36428052 0.05 ENSDART00000131300
unk
unkempt family zinc finger
chr2_-_40890004 0.05 ENSDART00000191746
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr7_+_42460302 0.05 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr19_+_1673599 0.05 ENSDART00000163127
klhl7
kelch-like family member 7
chr3_-_13147310 0.05 ENSDART00000160840
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr12_+_1469327 0.05 ENSDART00000059143
usp22
ubiquitin specific peptidase 22
chr23_-_14766902 0.05 ENSDART00000168113
gss
glutathione synthetase
chr17_+_10593398 0.05 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr7_+_51795667 0.05 ENSDART00000174201
ENSDART00000073839
slc38a7
solute carrier family 38, member 7
chr24_+_17260329 0.05 ENSDART00000129554
bmi1a
bmi1 polycomb ring finger oncogene 1a
chr10_+_16036246 0.05 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr5_+_28308774 0.05 ENSDART00000087708
si:dkeyp-86b9.1
si:dkeyp-86b9.1
chr19_+_9231766 0.05 ENSDART00000190617
kmt2ba
lysine (K)-specific methyltransferase 2Ba
chr24_+_17260001 0.05 ENSDART00000066765
bmi1a
bmi1 polycomb ring finger oncogene 1a
chr8_+_14855471 0.05 ENSDART00000134775
si:dkey-21p1.3
si:dkey-21p1.3
chr6_+_13779857 0.05 ENSDART00000154793
tmem198b
transmembrane protein 198b
chr7_+_15872357 0.05 ENSDART00000165757
pax6b
paired box 6b
chr5_+_13394543 0.05 ENSDART00000051669
ENSDART00000135921
tctn2
tectonic family member 2
chr18_+_1145571 0.05 ENSDART00000135055
rec114
REC114 meiotic recombination protein
chr22_-_621609 0.05 ENSDART00000137264
ENSDART00000106636
srsf3b
serine/arginine-rich splicing factor 3b
chr11_-_44876005 0.05 ENSDART00000192006
opn6a
opsin 6, group member a
chr3_+_726000 0.05 ENSDART00000158510
dicp1.17
diverse immunoglobulin domain-containing protein 1.17
chr16_+_35379720 0.05 ENSDART00000170497
si:dkey-34d22.2
si:dkey-34d22.2
chr6_-_47840465 0.04 ENSDART00000141986
lrig2
leucine-rich repeats and immunoglobulin-like domains 2

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx6-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.0 0.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.7 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.2 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.3 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0060074 synapse maturation(GO:0060074)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.1 GO:0043420 anthranilate metabolic process(GO:0043420)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0033700 phospholipid efflux(GO:0033700)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0097065 anterior head development(GO:0097065)
0.0 0.1 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.0 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0034359 mature chylomicron(GO:0034359)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.3 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 0.5 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.2 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase