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PRJNA207719: Tissue specific transcriptome profiling

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Results for lmx1ba+lmx1bb_lmx1al

Z-value: 0.86

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Transcription factors associated with lmx1ba+lmx1bb_lmx1al

Gene Symbol Gene ID Gene Info
lmx1bb
ENSDARG00000068365 LIM homeobox transcription factor 1, beta b
lmx1ba
ENSDARG00000104815 LIM homeobox transcription factor 1, beta a
lmx1al
ENSDARG00000077915 LIM homeobox transcription factor 1, alpha-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lmx1aldr11_v1_chr3_+_52806347_52806441-0.573.2e-01Click!
lmx1bbdr11_v1_chr8_-_33381913_333819130.405.0e-01Click!
lmx1badr11_v1_chr5_-_5147220_5147336-0.365.5e-01Click!

Activity profile of lmx1ba+lmx1bb_lmx1al motif

Sorted Z-values of lmx1ba+lmx1bb_lmx1al motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23431189 1.04 ENSDART00000004679
icn
ictacalcin
chr21_+_25777425 0.99 ENSDART00000021620
cldnd
claudin d
chr10_-_21362071 0.82 ENSDART00000125167
avd
avidin
chr23_-_31913231 0.80 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr10_-_21362320 0.67 ENSDART00000189789
avd
avidin
chr16_-_29387215 0.67 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr8_+_21353878 0.61 ENSDART00000056420
alas2
aminolevulinate, delta-, synthase 2
chr7_+_20503344 0.61 ENSDART00000157699
si:dkey-19b23.12
si:dkey-19b23.12
chr17_+_28103675 0.59 ENSDART00000188078
zgc:91908
zgc:91908
chr12_-_35830625 0.59 ENSDART00000180028
CU459056.1

chr6_+_41191482 0.58 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr25_+_31276842 0.58 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr24_-_35561672 0.57 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr1_-_18811517 0.56 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr24_-_2450597 0.56 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr9_+_8396755 0.56 ENSDART00000043067
zgc:171776
zgc:171776
chr13_-_31017960 0.52 ENSDART00000145287
wdfy4
WDFY family member 4
chr23_-_31913069 0.51 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr16_+_29509133 0.50 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr23_+_11285662 0.49 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr22_+_7439186 0.46 ENSDART00000190667
zgc:92041
zgc:92041
chr22_+_1170294 0.45 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr22_+_19552987 0.45 ENSDART00000105315
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr1_+_45056371 0.44 ENSDART00000073689
ENSDART00000167309
btr01
bloodthirsty-related gene family, member 1
chr18_+_20560442 0.44 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr22_-_17653143 0.43 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr22_-_17652914 0.43 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr8_-_20230559 0.42 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr8_-_14126646 0.40 ENSDART00000027225
bgna
biglycan a
chr20_-_40755614 0.40 ENSDART00000061247
cx32.3
connexin 32.3
chr18_+_19456648 0.39 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr18_+_15644559 0.39 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr3_-_61162750 0.39 ENSDART00000055064
pvalb8
parvalbumin 8
chr8_+_6576940 0.39 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr16_-_16761164 0.39 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr13_+_24750078 0.38 ENSDART00000021053
col17a1b
collagen, type XVII, alpha 1b
chr19_+_43297546 0.38 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr1_-_43905252 0.38 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
si:dkey-22i16.3
chr1_+_44173245 0.37 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr5_+_6954162 0.36 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr8_+_45334255 0.36 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr14_-_22113600 0.36 ENSDART00000113752
si:dkey-6i22.5
si:dkey-6i22.5
chr3_-_16719244 0.35 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr20_-_23426339 0.35 ENSDART00000004625
zar1
zygote arrest 1
chr22_+_19220459 0.35 ENSDART00000163070
si:dkey-21e2.7
si:dkey-21e2.7
chr25_-_3867990 0.35 ENSDART00000075663
cracr2b
calcium release activated channel regulator 2B
chr11_-_44801968 0.35 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr2_-_26596794 0.34 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr18_-_19456269 0.34 ENSDART00000060363
rpl4
ribosomal protein L4
chr16_+_23961276 0.34 ENSDART00000192754
apoeb
apolipoprotein Eb
chr18_+_3037998 0.34 ENSDART00000185844
ENSDART00000162657
rps3
ribosomal protein S3
chr1_-_10821584 0.34 ENSDART00000167452
ENSDART00000162137
crfb15
cytokine receptor family member B15
chr8_+_11425048 0.33 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr23_+_31913292 0.33 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr25_+_18475032 0.32 ENSDART00000073564
tes
testis derived transcript (3 LIM domains)
chr15_-_21877726 0.32 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr6_-_43283122 0.31 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr1_+_9966384 0.31 ENSDART00000132607
si:dkeyp-75b4.8
si:dkeyp-75b4.8
chr19_+_2631565 0.31 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr24_-_6078222 0.31 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr8_-_25034411 0.30 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr3_-_50443607 0.29 ENSDART00000074036
rcvrna
recoverin a
chr2_+_33326522 0.29 ENSDART00000056655
klf17
Kruppel-like factor 17
chr20_-_43663494 0.29 ENSDART00000144564
BX470188.1

chr15_+_31344472 0.29 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
or107-1
odorant receptor, family D, subfamily 107, member 1
chr2_+_30032303 0.28 ENSDART00000151841
rbm33b
RNA binding motif protein 33b
chr5_+_66433287 0.28 ENSDART00000170757
kntc1
kinetochore associated 1
chr16_-_51299061 0.28 ENSDART00000148677
serpinb1l4
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr18_+_20560616 0.28 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr23_+_39695827 0.28 ENSDART00000113893
ENSDART00000186679
tmco4
transmembrane and coiled-coil domains 4
chr17_+_25481466 0.27 ENSDART00000139451
aim1a
crystallin beta-gamma domain containing 1a
chr13_-_45155792 0.27 ENSDART00000163556
runx3
runt-related transcription factor 3
chr16_+_33902006 0.27 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr23_-_17003533 0.27 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr10_-_25217347 0.27 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr20_-_52902693 0.27 ENSDART00000166115
ENSDART00000161050
ctsbb
cathepsin Bb
chr7_+_7048245 0.27 ENSDART00000001649
actn3b
actinin alpha 3b
chr15_+_36457888 0.27 ENSDART00000155100
si:dkey-262k9.2
si:dkey-262k9.2
chr2_+_37227011 0.26 ENSDART00000126587
ENSDART00000084958
samd7
sterile alpha motif domain containing 7
chr16_+_26777473 0.26 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr22_-_15578402 0.26 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr1_-_5455498 0.25 ENSDART00000040368
ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr7_-_71389375 0.25 ENSDART00000128928
CABZ01074298.1

chr10_-_15340362 0.25 ENSDART00000148119
ENSDART00000127277
ENSDART00000154037
ENSDART00000189109
pum3
pumilio RNA-binding family member 3
chr24_-_27452488 0.25 ENSDART00000136433
ccl34b.8
chemokine (C-C motif) ligand 34b, duplicate 8
chr17_+_16090436 0.24 ENSDART00000136059
ENSDART00000138734
znf395a
zinc finger protein 395a
chr10_+_8885769 0.24 ENSDART00000139466
itga2.2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
chr24_-_38110779 0.24 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr9_-_50001606 0.23 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr11_+_35050253 0.23 ENSDART00000124800
fam212aa
family with sequence similarity 212, member Aa
chr25_-_21031007 0.23 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr2_+_19522082 0.23 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr25_+_13620555 0.23 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr7_+_20471315 0.23 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr5_+_36850650 0.22 ENSDART00000051186
nccrp1
non-specific cytotoxic cell receptor protein 1
chr3_-_32337653 0.22 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr8_-_23612462 0.22 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr3_+_46635527 0.22 ENSDART00000153971
si:dkey-248g21.1
si:dkey-248g21.1
chr13_+_27232848 0.22 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr3_-_15081874 0.22 ENSDART00000192532
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr8_+_30112655 0.22 ENSDART00000099027
fancc
Fanconi anemia, complementation group C
chr10_+_6884627 0.22 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr16_+_23913943 0.22 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr8_-_20230802 0.21 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr11_-_1550709 0.21 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr6_+_39098397 0.21 ENSDART00000003716
ENSDART00000188655
prss60.2
protease, serine, 60.2
chr7_+_2236317 0.21 ENSDART00000075859
zgc:172065
zgc:172065
chr14_+_22113331 0.20 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr5_-_7199998 0.20 ENSDART00000167316
CABZ01087502.1

chr4_-_9891874 0.20 ENSDART00000067193
adm2a
adrenomedullin 2a
chr17_-_26867725 0.20 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr13_+_28747934 0.20 ENSDART00000160176
ENSDART00000101633
ENSDART00000136318
prom2
prominin 2
chr3_-_36210344 0.20 ENSDART00000025326
csnk1da
casein kinase 1, delta a
chr1_-_10071422 0.20 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr14_+_35428152 0.20 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr9_-_9415000 0.19 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr20_-_37813863 0.19 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr17_-_2690083 0.19 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr10_-_34916208 0.19 ENSDART00000187371
ccna1
cyclin A1
chr16_-_42056137 0.19 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr11_-_45138857 0.19 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr20_-_6532462 0.19 ENSDART00000054653
mcm3l
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr18_-_40708537 0.19 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr19_+_43119014 0.19 ENSDART00000023156
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr23_-_31974060 0.18 ENSDART00000168087
BX927210.1

chr8_+_23152244 0.18 ENSDART00000036801
ENSDART00000184298
slc17a9a
solute carrier family 17 (vesicular nucleotide transporter), member 9a
chr3_+_1637358 0.18 ENSDART00000180266
CR394546.5

chr11_-_41853874 0.18 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr24_+_12835935 0.18 ENSDART00000114762
nanog
nanog homeobox
chr10_-_8053753 0.18 ENSDART00000162289
si:ch211-251f6.7
si:ch211-251f6.7
chr2_+_3201345 0.18 ENSDART00000130349
wnt9a
wingless-type MMTV integration site family, member 9A
chr15_-_43284021 0.18 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr5_+_33519943 0.18 ENSDART00000131316
ms4a17c.1
membrane-spanning 4-domains, subfamily A, member 17C.1
chr13_+_25449681 0.17 ENSDART00000101328
atoh7
atonal bHLH transcription factor 7
chr7_+_56577522 0.17 ENSDART00000149130
ENSDART00000149624
hp
haptoglobin
chr2_+_19633493 0.17 ENSDART00000147989
pimr54
Pim proto-oncogene, serine/threonine kinase, related 54
chr24_+_19415124 0.17 ENSDART00000186931
sulf1
sulfatase 1
chr3_+_27798094 0.17 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr23_-_16485190 0.17 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr8_-_44378391 0.17 ENSDART00000158784
ENSDART00000098138
si:busm1-228j01.6
si:busm1-228j01.6
chr23_+_2728095 0.17 ENSDART00000066086
zgc:114123
zgc:114123
chr15_-_2493771 0.17 ENSDART00000184906
neu4
sialidase 4
chr18_+_7073130 0.17 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr15_+_6109861 0.16 ENSDART00000185154
PCP4 (1 of many)
Purkinje cell protein 4
chr22_-_10121880 0.16 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr10_+_21867307 0.16 ENSDART00000126629
cbln17
cerebellin 17
chr20_+_46492175 0.16 ENSDART00000060695
zc3h14
zinc finger CCCH-type containing 14
chr10_+_29850330 0.16 ENSDART00000168898
hspa8
heat shock protein 8
chr19_-_5699703 0.15 ENSDART00000082050
zgc:174904
zgc:174904
chr22_-_13042992 0.15 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr7_+_25033924 0.15 ENSDART00000170873
sb:cb1058
sb:cb1058
chr24_-_40744672 0.15 ENSDART00000160672
CU633479.1

chr12_+_48803098 0.15 ENSDART00000074768
ppifb
peptidylprolyl isomerase Fb
chr7_-_31321027 0.15 ENSDART00000186878
CR356242.1

chr2_+_36112273 0.14 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr13_-_31008275 0.14 ENSDART00000139394
wdfy4
WDFY family member 4
chr25_-_18435481 0.14 ENSDART00000004771
poc1b
POC1 centriolar protein B
chr8_+_25034544 0.14 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr23_+_36122058 0.14 ENSDART00000184448
hoxc3a
homeobox C3a
chr16_-_38118003 0.14 ENSDART00000058667
si:dkey-23o4.6
si:dkey-23o4.6
chr16_-_38609146 0.14 ENSDART00000144651
eif3ea
eukaryotic translation initiation factor 3, subunit E, a
chr20_+_11731039 0.14 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr19_+_7152966 0.14 ENSDART00000080348
brd2a
bromodomain containing 2a
chr17_-_24575893 0.14 ENSDART00000141914
aftphb
aftiphilin b
chr6_-_18228358 0.14 ENSDART00000167937
p4hb
prolyl 4-hydroxylase, beta polypeptide
chr12_-_14143344 0.14 ENSDART00000152742
buc2l
bucky ball 2-like
chr3_-_13921173 0.14 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
si:dkey-61n16.5
chr9_+_50001746 0.14 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr1_+_52392511 0.13 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr15_+_34988148 0.13 ENSDART00000076269
ccdc105
coiled-coil domain containing 105
chr8_+_16758304 0.13 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr18_+_2228737 0.13 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr24_+_16985181 0.13 ENSDART00000135580
eif2s3
eukaryotic translation initiation factor 2, subunit 3 gamma
chr23_-_32162810 0.13 ENSDART00000155905
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr6_+_14301214 0.13 ENSDART00000129491
tmem182b
transmembrane protein 182b
chr10_+_16584382 0.13 ENSDART00000112039
CR790388.1

chr8_-_12867128 0.13 ENSDART00000142201
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr11_+_3254524 0.13 ENSDART00000159459
pmela
premelanosome protein a
chr14_+_40874608 0.13 ENSDART00000168448
si:ch211-106m9.1
si:ch211-106m9.1
chr12_+_16168342 0.13 ENSDART00000079326
ENSDART00000170024
lrp2b
low density lipoprotein receptor-related protein 2b
chr20_-_48485354 0.13 ENSDART00000124040
ENSDART00000148437
insm1a
insulinoma-associated 1a
chr17_-_21884323 0.12 ENSDART00000155574
cuzd1.1
CUB and zona pellucida-like domains 1, tandem duplicate 1
chr13_-_25720876 0.12 ENSDART00000142404
ENSDART00000146487
si:dkey-192p21.6
si:dkey-192p21.6
chr19_-_10330778 0.12 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
ccdc106b
coiled-coil domain containing 106b
chr23_+_31912882 0.12 ENSDART00000140505
armc1l
armadillo repeat containing 1, like
chr2_+_29842878 0.12 ENSDART00000131376
si:ch211-207d6.2
si:ch211-207d6.2
chr16_+_23303859 0.12 ENSDART00000006093
slc50a1
solute carrier family 50 (sugar efflux transporter), member 1
chr13_+_25720969 0.12 ENSDART00000046050
pcbd1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr3_+_17933132 0.12 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr19_+_30884960 0.12 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
yars
tyrosyl-tRNA synthetase
chr11_-_38533505 0.12 ENSDART00000113894
slc45a3
solute carrier family 45, member 3
chr4_+_76637548 0.12 ENSDART00000133799
ms4a17a.9
membrane-spanning 4-domains, subfamily A, member 17A.9
chr3_-_34072446 0.12 ENSDART00000151528
ighv8-2
immunoglobulin heavy variable 8-2
chr11_-_35171162 0.12 ENSDART00000017393
traip
TRAF-interacting protein
chr25_+_3549584 0.12 ENSDART00000165913
ccdc77
coiled-coil domain containing 77
chr3_+_23092762 0.12 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr23_-_33709964 0.12 ENSDART00000143333
ENSDART00000130338
pou6f1
POU class 6 homeobox 1
chr7_-_6445129 0.11 ENSDART00000172825
FP325123.2
Histone H3.2
chr19_+_30884706 0.11 ENSDART00000052126
yars
tyrosyl-tRNA synthetase
chr1_-_55248496 0.11 ENSDART00000098615
nanos3
nanos homolog 3

Network of associatons between targets according to the STRING database.

First level regulatory network of lmx1ba+lmx1bb_lmx1al

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060631 regulation of meiosis I(GO:0060631)
0.2 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.1 0.8 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.3 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) high-density lipoprotein particle assembly(GO:0034380)
0.1 0.2 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.2 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.4 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.1 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.2 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.4 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0070265 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.3 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.4 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.0 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.0 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.2 GO:2000344 binding of sperm to zona pellucida(GO:0007339) cell-cell recognition(GO:0009988) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.6 GO:0007602 phototransduction(GO:0007602)
0.0 0.0 GO:0034969 histone arginine methylation(GO:0034969)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0071914 prominosome(GO:0071914)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0009374 biotin binding(GO:0009374)
0.2 0.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.4 GO:0032052 bile acid binding(GO:0032052)
0.1 0.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 1.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.0 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates