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PRJNA207719: Tissue specific transcriptome profiling

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Results for mafa+mafbb

Z-value: 1.86

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Transcription factors associated with mafa+mafbb

Gene Symbol Gene ID Gene Info
mafa
ENSDARG00000015890 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
mafbb
ENSDARG00000070542 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb
mafbb
ENSDARG00000099120 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafadr11_v1_chr18_+_29402623_29402623-0.375.4e-01Click!
mafbbdr11_v1_chr11_-_25384213_25384213-0.029.7e-01Click!

Activity profile of mafa+mafbb motif

Sorted Z-values of mafa+mafbb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_24738188 2.00 ENSDART00000050238
vtg1
vitellogenin 1
chr3_-_18030938 1.85 ENSDART00000013540
si:ch73-141c7.1
si:ch73-141c7.1
chr22_-_24880824 1.65 ENSDART00000061165
vtg2
vitellogenin 2
chr10_+_10801564 1.65 ENSDART00000027026
ambp
alpha-1-microglobulin/bikunin precursor
chr10_+_10801719 1.65 ENSDART00000193648
ambp
alpha-1-microglobulin/bikunin precursor
chr22_-_24757785 1.56 ENSDART00000078225
vtg5
vitellogenin 5
chr13_-_20381485 1.56 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr2_+_25816843 1.53 ENSDART00000078639
slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
chr10_+_28428222 1.50 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr20_+_38285671 1.42 ENSDART00000061432
ccl38a.4
chemokine (C-C motif) ligand 38, duplicate 4
chr24_-_12938922 1.34 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr23_-_31428763 1.33 ENSDART00000053545
zgc:153284
zgc:153284
chr4_+_68562464 1.28 ENSDART00000192954
BX548011.4

chr25_+_31277415 1.23 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr11_-_40128722 1.19 ENSDART00000165781
fam83e
family with sequence similarity 83, member E
chr13_+_2908764 1.12 ENSDART00000162362
wu:fj16a03
wu:fj16a03
chr11_-_5865744 1.08 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr17_+_6217704 1.03 ENSDART00000129100
BX000363.1

chr10_+_26747755 1.02 ENSDART00000100329
f9b
coagulation factor IXb
chr1_-_54706039 1.02 ENSDART00000083633
exosc1
exosome component 1
chr21_-_43328056 1.01 ENSDART00000114955
sowahaa
sosondowah ankyrin repeat domain family member Aa
chr5_-_37116265 1.00 ENSDART00000057613
il13ra2
interleukin 13 receptor, alpha 2
chr16_+_46294337 0.99 ENSDART00000040769
nr2f5
nuclear receptor subfamily 2, group F, member 5
chr22_-_263117 0.98 ENSDART00000158134
zgc:66156
zgc:66156
chr14_-_763744 0.89 ENSDART00000165856
trim35-27
tripartite motif containing 35-27
chr1_-_7582859 0.88 ENSDART00000110696
mxb
myxovirus (influenza) resistance B
chr17_-_53359028 0.87 ENSDART00000185218
CABZ01068208.1

chr12_-_44043285 0.86 ENSDART00000163074
si:ch211-182p11.1
si:ch211-182p11.1
chr16_-_51299061 0.83 ENSDART00000148677
serpinb1l4
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr13_-_31025505 0.82 ENSDART00000137709
wdfy4
WDFY family member 4
chr19_-_35428815 0.82 ENSDART00000169006
ENSDART00000003167
ak2
adenylate kinase 2
chr15_+_21202820 0.80 ENSDART00000154036
si:dkey-52d15.2
si:dkey-52d15.2
chr20_-_14054083 0.78 ENSDART00000009549
rhag
Rh associated glycoprotein
chr10_-_29120515 0.77 ENSDART00000162016
ENSDART00000149140
zpld1a
zona pellucida-like domain containing 1a
chr23_+_7518294 0.75 ENSDART00000081536
hck
HCK proto-oncogene, Src family tyrosine kinase
chr7_+_35068036 0.74 ENSDART00000022139
zgc:136461
zgc:136461
chr16_-_12319822 0.73 ENSDART00000127453
ENSDART00000184526
trpv6
transient receptor potential cation channel, subfamily V, member 6
chr3_-_19517462 0.72 ENSDART00000162027
CU571315.2

chr19_+_1465004 0.71 ENSDART00000159157
CABZ01073736.1

chr8_+_50190742 0.70 ENSDART00000099863
slc25a37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr14_-_24001825 0.70 ENSDART00000130704
il4
interleukin 4
chr6_-_426041 0.69 ENSDART00000162789
fam83fb
family with sequence similarity 83, member Fb
chr1_+_51537250 0.68 ENSDART00000152789
etaa1
ETAA1, ATR kinase activator
chr5_-_30615901 0.66 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr13_-_37642890 0.65 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
si:dkey-188i13.9
chr5_-_65004578 0.64 ENSDART00000169287
ANXA1 (1 of many)
zgc:110283
chr14_-_7786585 0.64 ENSDART00000186440
tmem173
transmembrane protein 173
chr1_-_52498146 0.63 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr3_-_7948799 0.63 ENSDART00000163714
trim35-24
tripartite motif containing 35-24
chr21_-_28523548 0.62 ENSDART00000077910
epdl2
ependymin-like 2
chr4_-_58964138 0.62 ENSDART00000150259
si:ch211-64i20.3
si:ch211-64i20.3
chr15_-_41762530 0.61 ENSDART00000187125
ENSDART00000154971
ftr91
finTRIM family, member 91
chr19_+_48024457 0.61 ENSDART00000163823
kpnb1
karyopherin (importin) beta 1
chr15_+_34069746 0.61 ENSDART00000163513
arl4aa
ADP-ribosylation factor-like 4aa
chr12_+_34258139 0.60 ENSDART00000153127
socs3b
suppressor of cytokine signaling 3b
chr6_-_26895750 0.60 ENSDART00000011863
hdlbpa
high density lipoprotein binding protein a
chr24_-_26369185 0.58 ENSDART00000080039
lrrc31
leucine rich repeat containing 31
chr5_-_65004791 0.57 ENSDART00000180023
ANXA1 (1 of many)
zgc:110283
chr7_+_20393386 0.57 ENSDART00000173471
si:dkey-33c9.6
si:dkey-33c9.6
chr24_+_19518303 0.56 ENSDART00000027022
ENSDART00000056080
sulf1
sulfatase 1
chr23_+_24124684 0.55 ENSDART00000144478
si:dkey-21o19.2
si:dkey-21o19.2
chr19_+_7567763 0.55 ENSDART00000140411
s100a11
S100 calcium binding protein A11
chr9_+_32930622 0.54 ENSDART00000100928
cnga4
cyclic nucleotide gated channel alpha 4
chr24_-_23998897 0.53 ENSDART00000130053
zmp:0000000991
zmp:0000000991
chr17_-_20236228 0.53 ENSDART00000136490
ENSDART00000029380
bnip4
BCL2 interacting protein 4
chr20_-_43079478 0.52 ENSDART00000060982
snx9b
sorting nexin 9b
chr7_-_6415991 0.51 ENSDART00000173349
CU457819.3
Histone H3.2
chr5_-_67471375 0.51 ENSDART00000147009
si:dkey-251i10.2
si:dkey-251i10.2
chr14_+_3507326 0.50 ENSDART00000159326
gstp1
glutathione S-transferase pi 1
chr17_-_53353653 0.49 ENSDART00000180744
ENSDART00000026879
unm_sa911
un-named sa911
chr20_-_20410029 0.49 ENSDART00000192177
ENSDART00000063483
prkchb
protein kinase C, eta, b
chr20_-_16972351 0.48 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
si:ch73-74h11.1
chr16_-_16481046 0.48 ENSDART00000158704
nbeal2
neurobeachin-like 2
chr7_+_39386982 0.47 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr22_-_24285432 0.47 ENSDART00000164083
si:ch211-117l17.4
si:ch211-117l17.4
chr20_+_46385907 0.47 ENSDART00000060710
adgrg11
adhesion G protein-coupled receptor G11
chr24_-_42090635 0.47 ENSDART00000166413
ssr1
signal sequence receptor, alpha
chr21_+_21374277 0.47 ENSDART00000079431
rtn2b
reticulon 2b
chr2_-_38256589 0.47 ENSDART00000173064
si:ch211-14a17.10
si:ch211-14a17.10
chr8_+_23439340 0.46 ENSDART00000109932
ENSDART00000185469
foxp3b
forkhead box P3b
chr16_+_17089114 0.46 ENSDART00000173223
cd27
CD27 molecule
chr1_-_52497834 0.44 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr14_-_25928541 0.44 ENSDART00000145850
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr7_-_19043401 0.43 ENSDART00000158796
fcer1g
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr10_+_8527196 0.43 ENSDART00000141147
si:ch211-193e13.5
si:ch211-193e13.5
chr2_+_42260021 0.43 ENSDART00000124702
ENSDART00000140203
ENSDART00000184079
ENSDART00000193349
ftr04
finTRIM family, member 4
chr11_-_33960318 0.42 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr21_+_45659525 0.42 ENSDART00000160391
slc22a5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr10_+_38708099 0.41 ENSDART00000172306
tmprss2
transmembrane protease, serine 2
chr7_+_3442834 0.41 ENSDART00000138247
si:ch211-285c6.2
si:ch211-285c6.2
chr18_+_40643660 0.40 ENSDART00000134235
si:ch211-132b12.6
si:ch211-132b12.6
chr8_+_23436411 0.40 ENSDART00000140044
foxp3b
forkhead box P3b
chr12_+_20552190 0.38 ENSDART00000113224
gna13a
guanine nucleotide binding protein (G protein), alpha 13a
chr8_-_41228530 0.38 ENSDART00000165949
ENSDART00000173055
fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chr6_-_13783604 0.38 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
cryba2a
crystallin, beta A2a
chr13_-_25196758 0.37 ENSDART00000184722
adka
adenosine kinase a
chr8_-_22538588 0.37 ENSDART00000144041
csde1
cold shock domain containing E1, RNA-binding
chr4_-_70131926 0.37 ENSDART00000108511
si:ch211-208f21.3
si:ch211-208f21.3
chr3_-_33997763 0.37 ENSDART00000151461
ENSDART00000151307
ighz
immunoglobulin heavy constant zeta
chr3_+_23063718 0.36 ENSDART00000140225
ENSDART00000184431
b4galnt2.1
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 1
chr4_+_65057234 0.35 ENSDART00000162985
si:dkey-14o6.2
si:dkey-14o6.2
chr8_+_28629741 0.35 ENSDART00000163915
si:dkey-109a10.2
si:dkey-109a10.2
chr23_-_19500559 0.34 ENSDART00000177414
ENSDART00000145898
asb14b
ankyrin repeat and SOCS box containing 14b
chr1_-_30457062 0.34 ENSDART00000185318
ENSDART00000157924
ENSDART00000161380
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr14_-_49859747 0.33 ENSDART00000169456
ENSDART00000164967
nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr16_+_18974064 0.33 ENSDART00000079248
slc6a19b
solute carrier family 6 (neutral amino acid transporter), member 19b
chr18_-_8885792 0.33 ENSDART00000143619
si:dkey-95h12.1
si:dkey-95h12.1
chr4_+_42878556 0.33 ENSDART00000171047
si:zfos-451d2.2
si:zfos-451d2.2
chr3_+_709393 0.32 ENSDART00000191970
AL929520.3

chr19_-_7441686 0.32 ENSDART00000168194
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr6_+_40723554 0.32 ENSDART00000103833
slc26a6l
solute carrier family 26, member 6, like
chr4_+_77709678 0.32 ENSDART00000036856
AL935186.1

chr5_+_19413838 0.32 ENSDART00000089014
ENSDART00000146215
myo1ha
myosin IHa
chr20_-_23852174 0.31 ENSDART00000122414
si:dkey-15j16.6
si:dkey-15j16.6
chr6_-_35439406 0.31 ENSDART00000073784
rgs5a
regulator of G protein signaling 5a
chr12_-_3940768 0.31 ENSDART00000134292
zgc:92040
zgc:92040
chr11_+_42641404 0.31 ENSDART00000172641
ENSDART00000169938
il17rd
interleukin 17 receptor D
chr12_-_44019561 0.31 ENSDART00000165900
si:dkey-31i7.1
si:dkey-31i7.1
chr18_+_33725576 0.31 ENSDART00000146816
si:dkey-145c18.5
si:dkey-145c18.5
chr16_-_33806390 0.30 ENSDART00000160671
rspo1
R-spondin 1
chr5_+_38685089 0.30 ENSDART00000139743
si:dkey-58f10.10
si:dkey-58f10.10
chr16_-_30564319 0.30 ENSDART00000145087
lmna
lamin A
chr22_+_9003090 0.30 ENSDART00000106414
rnh1
ribonuclease/angiogenin inhibitor 1
chr10_+_10387328 0.30 ENSDART00000080904
sardh
sarcosine dehydrogenase
chr4_-_71708567 0.30 ENSDART00000182645
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr17_-_50488015 0.29 ENSDART00000106229
zgc:113886
zgc:113886
chr7_+_27317174 0.29 ENSDART00000193058
sox6
SRY (sex determining region Y)-box 6
chr6_+_43390387 0.29 ENSDART00000122793
mitfa
microphthalmia-associated transcription factor a
chr2_+_17525355 0.29 ENSDART00000074101
pimr196
Pim proto-oncogene, serine/threonine kinase, related 196
chr9_-_12624622 0.29 ENSDART00000146535
tspearb
thrombospondin-type laminin G domain and EAR repeats b
chr11_+_43401201 0.29 ENSDART00000190128
vipb
vasoactive intestinal peptide b
chr19_-_7441948 0.28 ENSDART00000003544
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr1_+_31054915 0.28 ENSDART00000148968
itga6b
integrin, alpha 6b
chr22_+_2510828 0.27 ENSDART00000115348
ENSDART00000145611
zgc:173726
zgc:173726
chr4_-_39448829 0.27 ENSDART00000168526
si:dkey-261o4.9
si:dkey-261o4.9
chr15_+_41932069 0.27 ENSDART00000143007
si:ch211-191a16.2
si:ch211-191a16.2
chr2_-_4496358 0.27 ENSDART00000158216
adipoqb
adiponectin, C1Q and collagen domain containing, b
chr9_+_6802641 0.27 ENSDART00000187278
FO203514.1

chr22_-_4892937 0.27 ENSDART00000147002
si:ch73-256j6.4
si:ch73-256j6.4
chr5_-_32338866 0.27 ENSDART00000017956
ENSDART00000047670
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr4_+_34121902 0.27 ENSDART00000170225
si:ch211-223g7.6
si:ch211-223g7.6
chr4_-_57340828 0.26 ENSDART00000193689
zgc:194906
zgc:194906
chr9_+_28116079 0.26 ENSDART00000101338
idh1
isocitrate dehydrogenase 1 (NADP+), soluble
chr21_+_19347655 0.26 ENSDART00000093155
hpse
heparanase
chr18_+_7456597 0.26 ENSDART00000142270
terb1
telomere repeat binding bouquet formation protein 1
chr8_+_36621598 0.25 ENSDART00000180389
magixb
MAGI family member, X-linked b
chr2_+_19163965 0.25 ENSDART00000166073
elovl1a
ELOVL fatty acid elongase 1a
chr5_+_9377005 0.24 ENSDART00000124924
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr9_+_13985567 0.24 ENSDART00000102296
cd28
CD28 molecule
chr19_+_23308419 0.24 ENSDART00000141558
irgf2
immunity-related GTPase family, f2
chr15_+_3790556 0.24 ENSDART00000181467
RNF14 (1 of many)
ring finger protein 14
chr5_+_38679623 0.24 ENSDART00000131879
ENSDART00000170010
si:dkey-58f10.11
si:dkey-58f10.10
si:dkey-58f10.11
si:dkey-58f10.10
chr22_+_28888781 0.23 ENSDART00000145629
pimr98
Pim proto-oncogene, serine/threonine kinase, related 98
chr4_-_36032930 0.22 ENSDART00000191414
zgc:174180
zgc:174180
chr22_+_2511045 0.21 ENSDART00000106425
zgc:173726
zgc:173726
chr7_-_25697285 0.21 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr4_-_71708855 0.21 ENSDART00000158819
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr8_-_554540 0.21 ENSDART00000163934
FO704758.1
Danio rerio uncharacterized LOC100329294 (LOC100329294), mRNA.
chr25_-_35045250 0.21 ENSDART00000156508
ENSDART00000126590
zgc:114046
zgc:114046
chr9_+_35015747 0.21 ENSDART00000140110
gabpa
GA binding protein transcription factor, alpha subunit
chr7_+_20383841 0.21 ENSDART00000052906
si:dkey-33c9.6
si:dkey-33c9.6
chr4_+_5317483 0.21 ENSDART00000150366
si:ch211-214j24.10
si:ch211-214j24.10
chr4_-_42397126 0.20 ENSDART00000162437
si:ch211-129p6.2
si:ch211-129p6.2
chr19_+_7453996 0.20 ENSDART00000147491
ENSDART00000136502
mindy1
MINDY lysine 48 deubiquitinase 1
chr6_+_21993613 0.19 ENSDART00000160750
ENSDART00000083070
thumpd3
THUMP domain containing 3
chr2_+_15069011 0.19 ENSDART00000145893
cnn3b
calponin 3, acidic b
chr5_-_26893310 0.19 ENSDART00000126669
lman2lb
lectin, mannose-binding 2-like b
chr8_-_50287949 0.19 ENSDART00000023639
nkx2.7
NK2 transcription factor related 7
chr19_-_29302249 0.18 ENSDART00000188751
srfbp1
serum response factor binding protein 1
chr7_+_57108823 0.18 ENSDART00000184943
ENSDART00000055956
enosf1
enolase superfamily member 1
chr1_+_50613868 0.18 ENSDART00000111114
HERC5
si:ch73-190m4.1
chr4_+_35901451 0.18 ENSDART00000131142
znf1088
zinc finger protein 1088
chr20_+_12830448 0.18 ENSDART00000164754
BX547930.4

chr14_+_146857 0.18 ENSDART00000122521
CABZ01088229.1

chr8_-_35960987 0.17 ENSDART00000160503
slc15a4
solute carrier family 15 (oligopeptide transporter), member 4
chr7_-_47282853 0.17 ENSDART00000169299
si:ch211-186j3.3
si:ch211-186j3.3
chr11_+_42765963 0.17 ENSDART00000156080
ENSDART00000179888
tdrd3
tudor domain containing 3
chr20_+_812012 0.17 ENSDART00000179299
ENSDART00000137135
mei4
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr24_+_3307857 0.16 ENSDART00000106527
gyg1b
glycogenin 1b
chr1_-_30510839 0.16 ENSDART00000168189
ENSDART00000174868
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr18_-_6151793 0.16 ENSDART00000122307
gcsha
glycine cleavage system protein H (aminomethyl carrier), a
chr19_-_43639331 0.16 ENSDART00000138009
ENSDART00000086138
fam83hb
family with sequence similarity 83, member Hb
chr23_-_16666583 0.15 ENSDART00000189804
ENSDART00000136496
sdcbp2
syndecan binding protein (syntenin) 2
chr16_+_31542645 0.15 ENSDART00000163724
SLA (1 of many)
Src like adaptor
chr6_+_58569808 0.14 ENSDART00000154393
helz2
helicase with zinc finger 2, transcriptional coactivator
chr18_+_10926197 0.14 ENSDART00000192387
ttc38
tetratricopeptide repeat domain 38
chr2_+_105748 0.14 ENSDART00000169601
CABZ01098670.1

chr15_+_45640906 0.14 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr13_-_25199260 0.14 ENSDART00000057605
adka
adenosine kinase a
chr11_+_43401592 0.14 ENSDART00000112468
vipb
vasoactive intestinal peptide b
chr16_+_23326085 0.13 ENSDART00000180935
krtcap2
keratinocyte associated protein 2
chr2_+_13694450 0.13 ENSDART00000077259
ENSDART00000189485
ebna1bp2
EBNA1 binding protein 2
chr2_+_25198648 0.12 ENSDART00000110922
ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr19_-_425145 0.12 ENSDART00000164905
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr9_-_30247961 0.12 ENSDART00000131519
si:dkey-100n23.3
si:dkey-100n23.3
chr4_+_54645654 0.12 ENSDART00000192864
si:ch211-227e10.1
si:ch211-227e10.1
chr1_+_49652967 0.12 ENSDART00000191296
tsga10
testis specific, 10
chr16_+_46410520 0.11 ENSDART00000131072
rpz2
rapunzel 2
chr9_+_35016201 0.11 ENSDART00000182404
gabpa
GA binding protein transcription factor, alpha subunit
chr18_-_45617146 0.10 ENSDART00000146543
wt1b
wilms tumor 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of mafa+mafbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.4 1.1 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.3 1.3 GO:0071548 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.3 1.9 GO:0050764 regulation of phagocytosis(GO:0050764)
0.2 0.7 GO:0002369 T cell cytokine production(GO:0002369)
0.2 0.8 GO:0015840 urea transport(GO:0015840)
0.2 0.7 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.5 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.8 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.4 GO:0007620 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.3 GO:1901052 sarcosine metabolic process(GO:1901052)
0.1 0.4 GO:2000048 activation of phospholipase D activity(GO:0031584) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 3.6 GO:0032355 response to estradiol(GO:0032355)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.3 GO:0090220 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0044209 AMP salvage(GO:0044209)
0.1 1.5 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.6 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 3.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.4 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.3 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.3 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 1.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 1.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.0 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 1.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0003207 cardiac chamber formation(GO:0003207)
0.0 1.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.6 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 1.0 GO:0007596 blood coagulation(GO:0007596)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0002031 G-protein coupled receptor internalization(GO:0002031)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 1.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.2 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.9 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.7 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 7.0 GO:0009986 cell surface(GO:0009986)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 1.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0008305 integrin complex(GO:0008305)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.2 1.9 GO:0048039 ubiquinone binding(GO:0048039)
0.2 1.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.4 GO:0019767 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.1 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 1.1 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.7 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.4 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.5 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 1.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 2.3 GO:0019901 protein kinase binding(GO:0019901)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation