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PRJNA207719: Tissue specific transcriptome profiling

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Results for maff+mafga+mafgb

Z-value: 1.38

Motif logo

Transcription factors associated with maff+mafga+mafgb

Gene Symbol Gene ID Gene Info
ENSDARG00000018109 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga
ENSDARG00000028957 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ENSDARG00000100097 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
ENSDARG00000111050 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafgbdr11_v1_chr11_+_45299447_452994470.682.1e-01Click!
mafgadr11_v1_chr3_-_55404985_554049850.583.0e-01Click!
maffdr11_v1_chr12_-_19346678_193466780.424.8e-01Click!

Activity profile of maff+mafga+mafgb motif

Sorted Z-values of maff+mafga+mafgb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_36040820 1.05 ENSDART00000003550
nicotinamide nucleotide adenylyltransferase 2
chr3_+_32526799 1.02 ENSDART00000185755
si:ch73-367p23.2
chr3_+_15907458 0.91 ENSDART00000163525
mitogen-activated protein kinase 8 interacting protein 3
chr3_+_15907297 0.88 ENSDART00000139206
mitogen-activated protein kinase 8 interacting protein 3
chr7_+_25059845 0.88 ENSDART00000077215
protein phosphatase 2, regulatory subunit B', beta
chr19_-_19339285 0.88 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr21_+_9666347 0.83 ENSDART00000163853
mitogen-activated protein kinase 10
chr13_+_36146415 0.82 ENSDART00000140301
si:ch211-259k16.3
chr6_+_27667359 0.81 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr21_-_45613564 0.77 ENSDART00000160324

chr6_-_35446110 0.74 ENSDART00000058773
regulator of G protein signaling 16
chr21_+_18353703 0.73 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr23_-_27345425 0.71 ENSDART00000022042
ENSDART00000191870
sodium channel, voltage gated, type VIII, alpha subunit a
chr2_+_20332044 0.71 ENSDART00000112131
phospholipid phosphatase related 4a
chr2_-_24996441 0.70 ENSDART00000144795
solute carrier family 35, member G2a
chr21_-_43606502 0.70 ENSDART00000151030
si:ch73-362m14.4
chr17_+_27134806 0.69 ENSDART00000151901
ribosomal protein S6 kinase a, polypeptide 1
chr23_-_29502287 0.69 ENSDART00000141075
ENSDART00000053807
kinesin family member 1B
chr7_-_24491614 0.69 ENSDART00000131063
si:dkeyp-75h12.5
chr10_-_27049170 0.68 ENSDART00000143451
cornichon family AMPA receptor auxiliary protein 2
chr15_-_44512461 0.68 ENSDART00000155456
glutamate receptor, ionotropic, AMPA 4a
chr16_-_12173554 0.66 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr11_+_25112269 0.66 ENSDART00000147546
ndrg family member 3a
chr23_-_4915118 0.65 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr16_-_29452039 0.65 ENSDART00000148960
si:ch211-113g11.6
chr6_-_12135741 0.64 ENSDART00000155090
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr19_+_25649626 0.63 ENSDART00000146947
tachykinin 1
chr14_-_30490763 0.62 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
mitochondrial calcium uptake family, member 3b
chr19_-_1961024 0.61 ENSDART00000108784
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr24_+_9744012 0.61 ENSDART00000129656
transmembrane protein 108
chr21_+_20901505 0.59 ENSDART00000132741
complement component 7b
chr20_+_27393668 0.59 ENSDART00000005473
transmembrane protein 179
chr3_-_32320537 0.59 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
chr6_-_51101834 0.59 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr10_+_1638876 0.58 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
small G protein signaling modulator 1b
chr12_-_10300101 0.57 ENSDART00000126428
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr18_+_3332999 0.57 ENSDART00000160857
glycerophosphodiester phosphodiesterase domain containing 4a
chr19_-_9867001 0.56 ENSDART00000091695
calcium channel, voltage-dependent, gamma subunit 7a
chr5_+_27137473 0.54 ENSDART00000181833
unc-5 netrin receptor Db
chr7_+_67486807 0.54 ENSDART00000159989
copine VII
chr21_-_28340977 0.53 ENSDART00000141629
neurexin 2a
chr6_-_31348999 0.53 ENSDART00000153734
DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_-_878473 0.53 ENSDART00000173567
si:cabz01080528.1
chr8_+_53452681 0.52 ENSDART00000166705
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr16_+_10777116 0.52 ENSDART00000190902
ATPase Na+/K+ transporting subunit alpha 3b
chr1_+_57331813 0.51 ENSDART00000152440
ENSDART00000062841
epsin 3b
chr8_+_14792830 0.51 ENSDART00000139972
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr22_-_11136625 0.51 ENSDART00000016873
ENSDART00000125561
ATPase H+ transporting accessory protein 2
chr5_+_65491390 0.51 ENSDART00000159921
si:dkey-21e5.1
chr10_+_29698467 0.50 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr7_+_23515966 0.48 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr20_+_20637866 0.47 ENSDART00000060203
ENSDART00000079079
reticulon 1b
chr23_+_216012 0.46 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
si:ch73-162j3.4
chr17_-_22062364 0.46 ENSDART00000114470
tau tubulin kinase 1b
chr2_+_20331445 0.46 ENSDART00000186880
phospholipid phosphatase related 4a
chr2_+_55916911 0.45 ENSDART00000189483
ENSDART00000183647
ENSDART00000083470
ataxia, cerebellar, Cayman type b
chr21_-_24632778 0.45 ENSDART00000132533
ENSDART00000058370
Rho GTPase activating protein 32b
chr1_-_10048514 0.45 ENSDART00000125358
ENSDART00000054835
ring finger protein 175
chr3_+_29600917 0.45 ENSDART00000048867
somatostatin receptor 3
chr14_-_2355833 0.45 ENSDART00000157677
si:ch73-233f7.6
chr8_+_53423408 0.45 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr4_-_13156971 0.44 ENSDART00000182164
glutamate receptor interacting protein 1
chr17_+_12698532 0.44 ENSDART00000064509
ENSDART00000136830
stathmin-like 4, like
chr18_-_8579907 0.44 ENSDART00000147284
si:ch211-220f12.1
chr2_-_32356539 0.43 ENSDART00000169316
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr2_+_36862473 0.43 ENSDART00000135624
si:dkey-193b15.8
chr2_-_24369087 0.43 ENSDART00000081237
plasmalemma vesicle associated protein a
chr13_+_40034176 0.42 ENSDART00000189797
golgin A7 family, member Bb
chr24_-_32408404 0.42 ENSDART00000144157
si:ch211-56a11.2
chr24_-_39771667 0.42 ENSDART00000181867
si:ch211-276f18.2
chr7_-_57933736 0.41 ENSDART00000142580
ankyrin 2b, neuronal
chr7_+_72882446 0.41 ENSDART00000131113
ENSDART00000174223
adhesion G protein-coupled receptor L3
chr5_+_23118470 0.40 ENSDART00000149893
neurite extension and migration factor a
chr9_-_18424844 0.40 ENSDART00000154351
ecto-NOX disulfide-thiol exchanger 1
chr3_+_31933893 0.40 ENSDART00000146509
ENSDART00000139644
lin-7 homolog B (C. elegans)
chr4_-_77267787 0.39 ENSDART00000190346
zgc:174310
chr11_-_41130239 0.39 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr21_+_9576176 0.39 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mitogen-activated protein kinase 10
chr6_-_10780698 0.38 ENSDART00000151714
G protein-coupled receptor 155b
chr13_+_28675686 0.38 ENSDART00000027213
internexin neuronal intermediate filament protein, alpha a
chr7_-_18730474 0.38 ENSDART00000170374
si:dkey-38l22.2
chr10_-_20175118 0.38 ENSDART00000014417
5-hydroxytryptamine (serotonin) receptor 7b
chr20_+_20638034 0.37 ENSDART00000189759
reticulon 1b
chr3_+_25508247 0.37 ENSDART00000039448
melanin-concentrating hormone receptor 1b
chr6_+_34512313 0.37 ENSDART00000102554
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr19_-_29887629 0.36 ENSDART00000066123
karyopherin alpha 6 (importin alpha 7)
chr6_-_33685325 0.36 ENSDART00000181883
microtubule associated serine/threonine kinase 2
chr21_+_13383413 0.35 ENSDART00000151345
zgc:113162
chr21_+_10794914 0.35 ENSDART00000084035
zinc finger protein 532
chr18_+_7286788 0.35 ENSDART00000022998
si:ch73-86n2.1
chr3_-_60142530 0.34 ENSDART00000153247
si:ch211-120g10.1
chr13_-_36545258 0.34 ENSDART00000186171

chr24_+_38301080 0.34 ENSDART00000105672
myosin binding protein C, fast type b
chr9_-_4506819 0.34 ENSDART00000113975
potassium inwardly-rectifying channel, subfamily J, member 3a
chr2_+_23222939 0.34 ENSDART00000026800
kinesin-associated protein 3b
chr13_+_28618086 0.34 ENSDART00000087001
cyclin and CBS domain divalent metal cation transport mediator 2a
chr4_-_64871624 0.34 ENSDART00000124817
zinc finger protein 988
chr8_+_50983551 0.33 ENSDART00000142061
si:dkey-32e23.4
chr9_-_30346279 0.32 ENSDART00000089488
synaptotagmin-like 5
chr7_-_42206720 0.32 ENSDART00000110907
integrin alpha FG-GAP repeat containing 1
chr17_-_24564674 0.32 ENSDART00000105435
ENSDART00000135086
ATP-binding cassette, sub-family H, member 1
chr17_+_20204122 0.32 ENSDART00000078672
gonadotropin-releasing hormone 3
chr20_-_27864964 0.32 ENSDART00000153311
synapse differentiation inducing 1-like
chr18_-_19350792 0.32 ENSDART00000147902
multiple EGF-like-domains 11
chr1_+_6817292 0.32 ENSDART00000145822
ENSDART00000092118
erb-b2 receptor tyrosine kinase 4a
chr3_-_22829710 0.31 ENSDART00000055659
cytochrome b561
chr7_+_42206543 0.31 ENSDART00000112543
phosphorylase kinase, beta
chr19_+_8985230 0.30 ENSDART00000018973
secretory carrier membrane protein 3
chr7_+_34290051 0.30 ENSDART00000123498
fin bud initiation factor b
chr5_+_36870737 0.29 ENSDART00000145182
solute carrier family 8 (sodium/calcium exchanger), member 2a
chr3_+_24189804 0.29 ENSDART00000134723
proline rich 15-like a
chr6_+_52064304 0.29 ENSDART00000153468
actin binding Rho activating protein a
chr5_-_18513950 0.29 ENSDART00000145878
si:dkey-215k6.1
chr10_+_21758811 0.29 ENSDART00000188827
protocadherin 1 gamma 11
chr24_+_32472155 0.29 ENSDART00000098859
neuronal differentiation 6a
chr18_-_12295092 0.28 ENSDART00000033248
family with sequence similarity 107, member B
chr12_-_22509069 0.28 ENSDART00000179755
ENSDART00000109707
neuralized E3 ubiquitin protein ligase 4
chr5_-_21422390 0.28 ENSDART00000144198
teneurin transmembrane protein 1
chr2_-_32505091 0.28 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr9_-_16133263 0.28 ENSDART00000077187
myosin IB
chr19_+_32947910 0.28 ENSDART00000052091
ATPase H+ transporting V1 subunit C1b
chr3_+_22905341 0.28 ENSDART00000111435
histone deacetylase 5
chr8_+_52491436 0.27 ENSDART00000164298
si:ch1073-392o20.1
chr10_+_42733210 0.27 ENSDART00000189832

chr5_+_25681174 0.27 ENSDART00000134773
zinc finger, AN1-type domain 5a
chr17_-_45009782 0.27 ENSDART00000123971
family with sequence similarity 161, member B
chr18_+_8231138 0.27 ENSDART00000140193
arylsulfatase A
chr8_+_39607466 0.27 ENSDART00000097427
musashi RNA-binding protein 1
chr11_-_22372072 0.26 ENSDART00000065996
transmembrane protein 183A
chr2_+_10642047 0.26 ENSDART00000091570
family with sequence similarity 69, member Aa
chr11_-_18791834 0.26 ENSDART00000156431
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr3_+_33300522 0.26 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr9_+_27411502 0.26 ENSDART00000143994
si:dkey-193n17.9
chr17_-_51938663 0.25 ENSDART00000179784
ergosterol biosynthesis 28 homolog
chr25_+_20077225 0.25 ENSDART00000136543
troponin I4b, tandem duplicate 1
chr12_-_48960308 0.25 ENSDART00000176247

chr6_+_18367388 0.25 ENSDART00000163394
diacylglycerol kinase, epsilon
chr16_-_21047872 0.25 ENSDART00000131582
chromobox homolog 3b
chr23_-_33640959 0.25 ENSDART00000187599
ENSDART00000189475
cysteine-serine-rich nuclear protein 2
chr5_-_31856681 0.25 ENSDART00000187817
protein kinase N3
chr12_+_6041575 0.25 ENSDART00000091868
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr19_-_13286722 0.24 ENSDART00000168296
ENSDART00000158330
zinc finger protein, FOG family member 2b
chr2_+_24700922 0.24 ENSDART00000170467
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr19_-_41991104 0.24 ENSDART00000087055
trio Rho guanine nucleotide exchange factor a
chr23_+_2760573 0.24 ENSDART00000129719
DNA topoisomerase I
chr7_-_19600181 0.24 ENSDART00000100757
oxidase (cytochrome c) assembly 1-like
chr5_+_25680845 0.24 ENSDART00000139701
ENSDART00000009952
zinc finger, AN1-type domain 5a
chr20_-_45040916 0.24 ENSDART00000190001
kelch-like family member 29
chr9_+_17423941 0.24 ENSDART00000112884
ENSDART00000155233
kelch repeat and BTB (POZ) domain containing 7
chr9_+_33174064 0.23 ENSDART00000131910
ENSDART00000078256
dopey family member 2
chr9_-_25255490 0.23 ENSDART00000141502
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a
chr16_+_26777473 0.23 ENSDART00000188870
cadherin 17, LI cadherin (liver-intestine)
chr8_-_54304381 0.22 ENSDART00000184177
rhodopsin
chr3_+_32403758 0.22 ENSDART00000156982
si:ch211-195b15.8
chr21_+_30194904 0.21 ENSDART00000137023
ENSDART00000078403
si:ch211-59d17.3
chr3_-_32169754 0.21 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr9_+_33158191 0.21 ENSDART00000180786
dopey family member 2
chr3_+_24190207 0.21 ENSDART00000034762
proline rich 15-like a
chr15_+_36966369 0.21 ENSDART00000163622
kirre like nephrin family adhesion molecule 3, like
chr5_-_41307550 0.21 ENSDART00000143446
natriuretic peptide receptor 3
chr14_-_48348973 0.21 ENSDART00000185822

chr10_-_32877348 0.21 ENSDART00000018977
ENSDART00000133421
RAB guanine nucleotide exchange factor (GEF) 1
chr5_+_61738276 0.20 ENSDART00000186256
RAS like family 10 member B
chr17_+_42027969 0.20 ENSDART00000147563
kizuna centrosomal protein
chr13_+_51579851 0.20 ENSDART00000163847
NK6 homeobox 2
chr1_-_11291324 0.20 ENSDART00000091205
sidekick cell adhesion molecule 1b
chr12_-_31422433 0.19 ENSDART00000186075
ENSDART00000153172
ENSDART00000066256
vesicle transport through interaction with t-SNAREs 1A
chr17_+_50657509 0.19 ENSDART00000179957
DDHD domain containing 1a
chr20_+_14968031 0.19 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vesicle-associated membrane protein 4
chr20_+_32224405 0.19 ENSDART00000062993
ENSDART00000147448
sestrin 1
chr1_+_35790082 0.19 ENSDART00000085051
hedgehog interacting protein
chr1_+_52518176 0.19 ENSDART00000003278
tachykinin receptor 3-like
chr15_-_5563551 0.19 ENSDART00000099520
ATG16 autophagy related 16-like 2 (S. cerevisiae)
chr14_-_48033073 0.19 ENSDART00000193115
ENSDART00000169300
ENSDART00000188036
ENSDART00000183432
ENSDART00000180973
Rap guanine nucleotide exchange factor (GEF) 2
chr13_-_33207367 0.19 ENSDART00000146138
ENSDART00000109667
ENSDART00000182741
thyroid hormone receptor interactor 11
chr23_+_37185247 0.19 ENSDART00000146269
von Willebrand factor A domain containing 5B1
chr7_+_7151832 0.19 ENSDART00000109485
galactose-3-O-sulfotransferase 3
chr7_-_72423666 0.19 ENSDART00000191214
rabphilin 3A homolog (mouse), b
chr4_+_25912308 0.19 ENSDART00000167845
ENSDART00000136927
vezatin, adherens junctions transmembrane protein
chr20_+_27331008 0.19 ENSDART00000141486
protein phosphatase 4, regulatory subunit 4
chr25_+_33063762 0.19 ENSDART00000189974
talin 2b
chr16_-_26435431 0.18 ENSDART00000187526
multiple EGF-like-domains 8
chr7_+_22702437 0.18 ENSDART00000182054
si:dkey-165a24.9
chr12_+_27024676 0.18 ENSDART00000153104
male-specific lethal 1 homolog b (Drosophila)
chr12_+_49125510 0.18 ENSDART00000185804

chr4_-_41269844 0.18 ENSDART00000186177

chr7_+_42208859 0.18 ENSDART00000148643
phosphorylase kinase, beta
chr16_+_43077909 0.18 ENSDART00000014140
RUN domain containing 3b
chr10_-_1320114 0.18 ENSDART00000073617
opsin 4xa
chr25_-_554142 0.18 ENSDART00000028997
myosin IXAb
chr6_-_36182115 0.18 ENSDART00000154639
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 2
chr4_+_25912654 0.18 ENSDART00000109508
ENSDART00000134218
vezatin, adherens junctions transmembrane protein
chr13_+_10023256 0.18 ENSDART00000110035
S1 RNA binding domain 1
chr17_+_24722646 0.17 ENSDART00000138356
mitochondrial fission regulator 1-like
chr14_+_34547554 0.17 ENSDART00000074819
gamma-aminobutyric acid (GABA) A receptor, pi
chr10_-_27009413 0.17 ENSDART00000139942
ENSDART00000146983
ENSDART00000132352
ubiquinol-cytochrome c reductase complex assembly factor 3
chr22_-_24858042 0.17 ENSDART00000137998
ENSDART00000078216
ENSDART00000138378
vitellogenin 7
chr13_+_1015749 0.17 ENSDART00000190982
prokineticin receptor 1b
chr21_-_2209012 0.17 ENSDART00000158345
zgc:162971
chr10_-_26512742 0.17 ENSDART00000135951
si:dkey-5g14.1

Network of associatons between targets according to the STRING database.

First level regulatory network of maff+mafga+mafgb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 0.7 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.2 0.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.6 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.4 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.1 0.9 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0007624 ultradian rhythm(GO:0007624)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.0 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.4 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.3 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 0.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.9 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.5 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.2 GO:0039694 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 1.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0002931 response to ischemia(GO:0002931)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.1 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 1.3 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.1 GO:0060585 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.2 GO:1990253 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031) cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.1 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.5 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.2 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 2.0 GO:0070509 calcium ion import(GO:0070509)
0.0 0.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.6 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.1 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.2 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0009202 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) dGDP metabolic process(GO:0046066)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.5 GO:0042310 vasoconstriction(GO:0042310)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.2 GO:0030431 sleep(GO:0030431)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.2 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.1 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.6 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.6 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.4 GO:0005883 neurofilament(GO:0005883)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.6 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.6 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.1 1.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.1 1.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 0.3 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.9 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 1.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.5 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression