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PRJNA207719: Tissue specific transcriptome profiling

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Results for mecom

Z-value: 0.72

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Transcription factors associated with mecom

Gene Symbol Gene ID Gene Info
mecom
ENSDARG00000060808 MDS1 and EVI1 complex locus

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mecomdr11_v1_chr15_-_35410860_354108600.751.4e-01Click!

Activity profile of mecom motif

Sorted Z-values of mecom motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61203203 0.66 ENSDART00000171787
pvalb1
parvalbumin 1
chr20_-_34801181 0.48 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr14_+_35691889 0.47 ENSDART00000074685
glrbb
glycine receptor, beta b
chr15_+_22311803 0.43 ENSDART00000150182
hepacama
hepatic and glial cell adhesion molecule a
chr1_-_45553602 0.43 ENSDART00000143664
grin2bb
glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b
chr1_+_31110817 0.43 ENSDART00000137863
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr2_-_44283554 0.39 ENSDART00000184684
mpz
myelin protein zero
chr17_-_125091 0.38 ENSDART00000158825
actc1b
actin, alpha, cardiac muscle 1b
chr16_-_52879741 0.34 ENSDART00000166470
TPPP
tubulin polymerization promoting protein
chr10_-_31782616 0.34 ENSDART00000128839
fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr7_-_38612230 0.32 ENSDART00000173678
c1qtnf4
C1q and TNF related 4
chr3_-_32817274 0.32 ENSDART00000142582
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr17_+_29348013 0.31 ENSDART00000188885
ENSDART00000192005
ENSDART00000190484
ENSDART00000188565
kctd3
potassium channel tetramerization domain containing 3
chr21_+_7582036 0.29 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr15_-_23647078 0.28 ENSDART00000059366
ckmb
creatine kinase, muscle b
chr9_+_38983895 0.26 ENSDART00000144893
map2
microtubule-associated protein 2
chr2_+_38554260 0.26 ENSDART00000171527
cdh24b
cadherin 24, type 2b
chr19_+_16222618 0.26 ENSDART00000137189
ENSDART00000169246
ENSDART00000190583
ENSDART00000189521
ptprua
protein tyrosine phosphatase, receptor type, U, a
chr11_-_3343463 0.25 ENSDART00000066177
tuba2
tubulin, alpha 2
chr13_-_11644806 0.25 ENSDART00000169953
dctn1b
dynactin 1b
chr21_+_5209716 0.25 ENSDART00000102539
ENSDART00000053148
ENSDART00000102536
st8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr11_+_39672874 0.25 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr24_-_15648636 0.25 ENSDART00000136200
cbln2b
cerebellin 2b precursor
chr3_+_32443395 0.25 ENSDART00000188447
prr12b
proline rich 12b
chr21_-_12119711 0.24 ENSDART00000131538
celf4
CUGBP, Elav-like family member 4
chr20_+_49787584 0.24 ENSDART00000193458
ENSDART00000181511
ENSDART00000185850
ENSDART00000185613
ENSDART00000191671
CABZ01078261.1

chr22_-_29242347 0.24 ENSDART00000040761
pvalb7
parvalbumin 7
chr22_+_11535131 0.24 ENSDART00000113930
npb
neuropeptide B
chr4_+_26628822 0.24 ENSDART00000191030
ENSDART00000186113
ENSDART00000186764
ENSDART00000165158
iqsec3a
IQ motif and Sec7 domain 3a
chr15_-_32383529 0.23 ENSDART00000028349
c4
complement component 4
chr8_-_46572298 0.23 ENSDART00000030470
sult1st3
sulfotransferase family 1, cytosolic sulfotransferase 3
chr22_+_33362552 0.23 ENSDART00000101580
nicn1
nicolin 1
chr20_+_1996202 0.23 ENSDART00000184143
CABZ01092781.1

chr11_-_37509001 0.23 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr22_-_15385442 0.23 ENSDART00000090975
tmem264
transmembrane protein 264
chr8_+_48801402 0.22 ENSDART00000098363
tprg1l
tumor protein p63 regulated 1-like
chr8_-_31369161 0.22 ENSDART00000019937
gadd45ga
growth arrest and DNA-damage-inducible, gamma a
chr16_+_23924040 0.22 ENSDART00000161124
si:dkey-7f3.14
si:dkey-7f3.14
chr4_-_27398385 0.21 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr9_+_30720048 0.21 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr2_-_1188707 0.21 ENSDART00000066378
CABZ01084564.1

chr16_+_30959423 0.21 ENSDART00000136824
gstk2
glutathione S-transferase kappa 2
chr19_+_42693855 0.20 ENSDART00000136873
clasp2
cytoplasmic linker associated protein 2
chr23_+_44745317 0.20 ENSDART00000165654
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr17_+_33495194 0.20 ENSDART00000033691
pth2
parathyroid hormone 2
chr21_+_21326038 0.19 ENSDART00000089898
qpctlb
glutaminyl-peptide cyclotransferase-like b
chr24_+_41915878 0.19 ENSDART00000171523
TMEM200C
transmembrane protein 200C
chr2_+_2563192 0.19 ENSDART00000055713
CABZ01033000.1

chr18_-_21271373 0.19 ENSDART00000060001
pnp6
purine nucleoside phosphorylase 6
chr5_+_44190974 0.19 ENSDART00000182634
ENSDART00000190626
TMEM8B
si:dkey-84j12.1
chr17_+_13763425 0.19 ENSDART00000105175
lrfn5a
leucine rich repeat and fibronectin type III domain containing 5a
chr5_-_10946232 0.19 ENSDART00000163139
ENSDART00000031265
rtn4r
reticulon 4 receptor
chr12_-_6551681 0.18 ENSDART00000145413
si:ch211-253p2.2
si:ch211-253p2.2
chr15_+_16908085 0.18 ENSDART00000186870
ypel2b
yippee-like 2b
chr11_+_35364445 0.18 ENSDART00000125766
camkvb
CaM kinase-like vesicle-associated b
chr13_-_33822550 0.18 ENSDART00000143703
flrt3
fibronectin leucine rich transmembrane 3
chr10_+_22012389 0.18 ENSDART00000035188
kcnip1b
Kv channel interacting protein 1 b
chr17_+_26981132 0.18 ENSDART00000156672
si:dkey-221l4.11
si:dkey-221l4.11
chr15_-_32383340 0.17 ENSDART00000185632
c4
complement component 4
chr1_+_34181581 0.17 ENSDART00000146042
epha6
eph receptor A6
chr10_-_30785501 0.17 ENSDART00000020054
opcml
opioid binding protein/cell adhesion molecule-like
chr25_-_4148719 0.16 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr7_+_10351038 0.16 ENSDART00000173256
si:cabz01029535.1
si:cabz01029535.1
chr1_+_37752171 0.16 ENSDART00000183247
ENSDART00000189756
ENSDART00000139448
GALNTL6
si:ch211-15e22.3
chr24_-_5889878 0.16 ENSDART00000077951
pcolce2b
procollagen C-endopeptidase enhancer 2b
chr25_-_1235457 0.16 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr9_-_9348058 0.16 ENSDART00000132257
zgc:113337
zgc:113337
chr1_+_9071324 0.16 ENSDART00000184194
BX004779.2

chr14_+_36738069 0.16 ENSDART00000105590
tdo2a
tryptophan 2,3-dioxygenase a
chr6_-_25181012 0.16 ENSDART00000161585
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr6_-_40697585 0.16 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr8_+_36948256 0.16 ENSDART00000140410
iqsec2b
IQ motif and Sec7 domain 2b
chr24_-_30096666 0.15 ENSDART00000183285
plppr4b
phospholipid phosphatase related 4b
chr5_-_65662996 0.15 ENSDART00000147707
camsap1b
calmodulin regulated spectrin-associated protein 1b
chr24_+_28525507 0.14 ENSDART00000191121
arhgap29a
Rho GTPase activating protein 29a
chr16_+_14029283 0.14 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr23_-_30781875 0.14 ENSDART00000114628
ENSDART00000180949
ENSDART00000191313
myt1a
myelin transcription factor 1a
chr24_-_31843173 0.14 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr14_-_2187202 0.14 ENSDART00000160205
pcdh2ab12
protocadherin 2 alpha b 12
chr14_+_22591624 0.14 ENSDART00000108987
gfra4b
GDNF family receptor alpha 4b
chr16_+_12836143 0.14 ENSDART00000067741
cacng6b
calcium channel, voltage-dependent, gamma subunit 6b
chr18_+_8346920 0.14 ENSDART00000083421
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr1_+_33383971 0.14 ENSDART00000150043
dhrsx
dehydrogenase/reductase (SDR family) X-linked
chr9_+_29585943 0.13 ENSDART00000185989
ENSDART00000115290
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr7_+_66634167 0.13 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr22_-_5958066 0.13 ENSDART00000145821
si:rp71-36a1.3
si:rp71-36a1.3
chr5_+_49744713 0.13 ENSDART00000133384
nr2f1a
nuclear receptor subfamily 2, group F, member 1a
chr11_-_37359416 0.13 ENSDART00000159184
erc2
ELKS/RAB6-interacting/CAST family member 2
chr20_+_38322444 0.13 ENSDART00000161741
ENSDART00000132241
ENSDART00000148936
ENSDART00000149623
stum
stum, mechanosensory transduction mediator homolog
chr21_+_41743493 0.13 ENSDART00000192669
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr20_-_5369105 0.13 ENSDART00000114316
sptlc2b
serine palmitoyltransferase, long chain base subunit 2b
chr19_+_17259912 0.12 ENSDART00000078951
MANEAL
si:ch211-30b16.2
chr22_-_17256573 0.12 ENSDART00000136119
ENSDART00000062891
nphs2
nephrosis 2, idiopathic, steroid-resistant (podocin)
chr6_-_6423885 0.12 ENSDART00000092257
si:ch211-194e18.2
si:ch211-194e18.2
chr18_+_16330025 0.12 ENSDART00000142353
nts
neurotensin
chr14_-_47963115 0.11 ENSDART00000003826
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_+_38758261 0.11 ENSDART00000182756
wdr17
WD repeat domain 17
chr13_-_39830999 0.11 ENSDART00000115089
zgc:171482
zgc:171482
chr3_+_37824268 0.11 ENSDART00000137038
asic2
acid-sensing (proton-gated) ion channel 2
chr3_+_32789605 0.11 ENSDART00000171895
tbc1d10b
TBC1 domain family, member 10b
chr3_-_18274691 0.11 ENSDART00000161140
BX649434.3

chr9_+_31534601 0.11 ENSDART00000133094
si:ch211-168k14.2
si:ch211-168k14.2
chr23_+_17926279 0.11 ENSDART00000012540
chia.4
chitinase, acidic.4
chr12_+_38774860 0.10 ENSDART00000130371
kif19
kinesin family member 19
chr2_-_3678029 0.10 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr2_+_29976419 0.10 ENSDART00000056748
en2b
engrailed homeobox 2b
chr5_-_31926906 0.10 ENSDART00000187340
ssh1b
slingshot protein phosphatase 1b
chr1_+_38758445 0.10 ENSDART00000136300
wdr17
WD repeat domain 17
chr18_+_16246806 0.10 ENSDART00000142584
alx1
ALX homeobox 1
chr21_-_30658509 0.10 ENSDART00000139764
si:dkey-22f5.9
si:dkey-22f5.9
chr10_+_35152928 0.10 ENSDART00000063418
nsun5
NOP2/Sun domain family, member 5
chr17_-_12758171 0.10 ENSDART00000131564
brms1la
breast cancer metastasis-suppressor 1-like a
chr19_+_19511394 0.10 ENSDART00000172410
jazf1a
JAZF zinc finger 1a
chr7_+_16912837 0.10 ENSDART00000186956
nav2a
neuron navigator 2a
chr4_-_8902406 0.10 ENSDART00000192962
mpped1
metallophosphoesterase domain containing 1
chr11_-_41130239 0.10 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr6_-_34008827 0.10 ENSDART00000191183
ENSDART00000003701
ENSDART00000192502
tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr3_-_33437796 0.10 ENSDART00000075499
si:dkey-283b1.7
si:dkey-283b1.7
chr6_-_50203682 0.09 ENSDART00000083999
ENSDART00000143050
raly
RALY heterogeneous nuclear ribonucleoprotein
chr22_-_17611742 0.09 ENSDART00000144031
gpx4a
glutathione peroxidase 4a
chr11_-_42755108 0.09 ENSDART00000185255
CU459094.1

chr10_+_41914084 0.09 ENSDART00000009227
orai1b
ORAI calcium release-activated calcium modulator 1b
chr13_-_39830816 0.09 ENSDART00000138981
zgc:171482
zgc:171482
chr4_+_10721795 0.09 ENSDART00000136000
ENSDART00000067253
stab2
stabilin 2
chr9_-_25443094 0.09 ENSDART00000105492
acvr2aa
activin A receptor type 2Aa
chr25_-_4235037 0.09 ENSDART00000093003
syt7a
synaptotagmin VIIa
chr17_-_12926456 0.09 ENSDART00000044126
INSM2
INSM transcriptional repressor 2
chr23_+_42304602 0.09 ENSDART00000166004
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr2_+_51818039 0.09 ENSDART00000170353
acvr2bb
activin A receptor type 2Bb
chr9_+_13714379 0.09 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr22_+_14051245 0.09 ENSDART00000043711
ENSDART00000164259
aox6
aldehyde oxidase 6
chr10_+_34394454 0.09 ENSDART00000110121
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr20_-_5052786 0.09 ENSDART00000138818
ENSDART00000181655
ENSDART00000164274
arid1b
AT rich interactive domain 1B (SWI1-like)
chr25_+_2229301 0.09 ENSDART00000180198
pparab
peroxisome proliferator-activated receptor alpha b
chr5_-_13086616 0.09 ENSDART00000051664
ypel1
yippee-like 1
chr2_-_1548330 0.09 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr20_+_48803248 0.09 ENSDART00000164006
nkx2.4b
NK2 homeobox 4b
chr13_+_12174937 0.09 ENSDART00000171683
gabrg1
gamma-aminobutyric acid type A receptor gamma1 subunit
chr15_+_5028608 0.08 ENSDART00000092809
abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr23_-_36439961 0.08 ENSDART00000187907
csad
cysteine sulfinic acid decarboxylase
chr13_-_18695289 0.08 ENSDART00000176809
sfxn3
sideroflexin 3
chr7_+_44445595 0.08 ENSDART00000108766
cdh5
cadherin 5
chr17_-_15149192 0.08 ENSDART00000180511
ENSDART00000103405
gch1
GTP cyclohydrolase 1
chr11_-_23322182 0.08 ENSDART00000111289
kiss1
KiSS-1 metastasis-suppressor
chr20_-_36671660 0.08 ENSDART00000134819
slc5a6a
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6a
chr10_-_15672862 0.08 ENSDART00000109231
mamdc2b
MAM domain containing 2b
chr15_-_8517555 0.08 ENSDART00000140213
npas1
neuronal PAS domain protein 1
chr2_+_25816843 0.08 ENSDART00000078639
slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
chr23_+_13928346 0.08 ENSDART00000155326
si:dkey-90a13.10
si:dkey-90a13.10
chr9_+_48455909 0.08 ENSDART00000167243
lrp2a
low density lipoprotein receptor-related protein 2a
chr25_+_26844028 0.08 ENSDART00000127274
ENSDART00000156179
sema7a
semaphorin 7A
chr2_+_15776649 0.08 ENSDART00000156535
vav3b
vav 3 guanine nucleotide exchange factor b
chr10_-_8434816 0.08 ENSDART00000108643
tctn1
tectonic family member 1
chr12_+_27068525 0.08 ENSDART00000188634
srcap
Snf2-related CREBBP activator protein
chr5_+_28161079 0.08 ENSDART00000141109
tacr1a
tachykinin receptor 1a
chr21_-_38031038 0.08 ENSDART00000179483
ENSDART00000076238
rbm41
RNA binding motif protein 41
chr19_-_42557416 0.08 ENSDART00000163217
ENSDART00000128278
ENSDART00000162304
ENSDART00000166556
si:dkey-267n13.1
si:dkey-267n13.1
chr13_-_49707885 0.08 ENSDART00000189805
ENSDART00000128415
tomm20a
translocase of outer mitochondrial membrane 20
chr8_-_49499457 0.08 ENSDART00000098326
opn7d
opsin 7, group member d
chr11_+_4953964 0.08 ENSDART00000092552
ptprga
protein tyrosine phosphatase, receptor type, g a
chr19_+_37620342 0.07 ENSDART00000158960
thsd7aa
thrombospondin, type I, domain containing 7Aa
chr20_-_7000225 0.07 ENSDART00000100098
adcy1a
adenylate cyclase 1a
chr13_+_30172645 0.07 ENSDART00000137114
pald1b
phosphatase domain containing, paladin 1b
chr25_+_25438165 0.07 ENSDART00000161369
LRRC56
si:ch211-103e16.5
chr5_-_5147041 0.07 ENSDART00000180236
lmx1ba
LIM homeobox transcription factor 1, beta a
chr2_-_10188598 0.07 ENSDART00000189122
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr23_+_30835589 0.07 ENSDART00000154145
npbwr2a
neuropeptides B/W receptor 2a
chr25_+_33002963 0.07 ENSDART00000187366
CABZ01046980.1

chr24_+_23742690 0.07 ENSDART00000130162
TCF24
transcription factor 24
chr9_-_9705512 0.07 ENSDART00000149021
gpr156
G protein-coupled receptor 156
chr23_-_20154422 0.07 ENSDART00000132025
usp19
ubiquitin specific peptidase 19
chr22_+_19111444 0.07 ENSDART00000109655
fgf22
fibroblast growth factor 22
chr9_+_10014817 0.07 ENSDART00000132065
nxph2a
neurexophilin 2a
chr8_+_1187928 0.07 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr9_+_1138323 0.07 ENSDART00000190352
ENSDART00000190387
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr6_-_46861676 0.07 ENSDART00000188712
ENSDART00000190148
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr5_+_19165949 0.06 ENSDART00000140710
unc13ba
unc-13 homolog Ba (C. elegans)
chr13_-_11971148 0.06 ENSDART00000066230
ENSDART00000185614
ARL3 (1 of many)
zgc:110197
chr1_+_36771954 0.06 ENSDART00000149022
arhgap10
Rho GTPase activating protein 10
chr24_-_26460853 0.06 ENSDART00000078628
slc7a14b
solute carrier family 7, member 14b
chr21_+_6556635 0.06 ENSDART00000139598
col5a1
procollagen, type V, alpha 1
chr19_+_27342479 0.06 ENSDART00000184687
ddx39b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr23_+_4646194 0.06 ENSDART00000092344
LO017700.1

chr21_+_15704556 0.06 ENSDART00000024858
ENSDART00000146909
chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr9_+_10014514 0.06 ENSDART00000185590
nxph2a
neurexophilin 2a
chr13_+_29771463 0.06 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
pax2a
paired box 2a
chr9_+_31075896 0.06 ENSDART00000188042
clybl
citrate lyase beta like
chr4_+_27131725 0.06 ENSDART00000013083
brd1a
bromodomain containing 1a
chr10_+_9159279 0.06 ENSDART00000064968
rasgef1bb
RasGEF domain family, member 1Bb
chr1_-_33351780 0.06 ENSDART00000178996
gyg2
glycogenin 2
chr17_-_30702411 0.06 ENSDART00000114358
zgc:194392
zgc:194392
chr6_-_12902772 0.06 ENSDART00000172237
ical1
islet cell autoantigen 1-like
chr23_+_40410644 0.05 ENSDART00000056328
elovl4b
ELOVL fatty acid elongase 4b
chr16_+_10972733 0.05 ENSDART00000049323
pou2f2a
POU class 2 homeobox 2a
chr3_+_24511959 0.05 ENSDART00000133898
dnal4a
dynein, axonemal, light chain 4a
chr7_+_21887307 0.05 ENSDART00000052871
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr5_+_31965845 0.05 ENSDART00000112968
myo1hb
myosin IHb
chr7_-_17028015 0.05 ENSDART00000022441
dbx1a
developing brain homeobox 1a
chr2_-_4070850 0.05 ENSDART00000159990
yme1l1b
YME1-like 1b
chr22_+_35275468 0.05 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of mecom

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0021767 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.2 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.1 GO:0010934 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0071312 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0060079 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.3 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955) regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0009712 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 0.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709)
0.0 0.7 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.1 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.0 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0016496 substance P receptor activity(GO:0016496)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation