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PRJNA207719: Tissue specific transcriptome profiling

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Results for mef2b

Z-value: 1.83

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Transcription factors associated with mef2b

Gene Symbol Gene ID Gene Info
mef2b
ENSDARG00000093170 myocyte enhancer factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2bdr11_v1_chr22_+_18188045_181880450.682.0e-01Click!

Activity profile of mef2b motif

Sorted Z-values of mef2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_22930627 2.12 ENSDART00000187860
sypa
synaptophysin a
chr1_+_45080897 2.09 ENSDART00000129819
si:ch211-151p13.8
si:ch211-151p13.8
chr6_-_14139503 1.75 ENSDART00000089577
cacnb4b
calcium channel, voltage-dependent, beta 4b subunit
chr1_+_8601935 1.73 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr5_-_31926906 1.67 ENSDART00000187340
ssh1b
slingshot protein phosphatase 1b
chr17_-_12336987 1.67 ENSDART00000172001
snap25b
synaptosomal-associated protein, 25b
chr25_-_13381854 1.66 ENSDART00000164621
ENSDART00000169129
ndrg4
NDRG family member 4
chr10_-_22845485 1.58 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr21_+_11684830 1.42 ENSDART00000147473
pcsk1
proprotein convertase subtilisin/kexin type 1
chr5_+_64368770 1.37 ENSDART00000162246
plpp7
phospholipid phosphatase 7 (inactive)
chr21_+_11685009 1.35 ENSDART00000014668
pcsk1
proprotein convertase subtilisin/kexin type 1
chr10_-_8032885 1.30 ENSDART00000188619
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr3_-_61205711 1.27 ENSDART00000055062
pvalb1
parvalbumin 1
chr10_-_24371312 1.25 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr10_-_8033468 1.15 ENSDART00000140476
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr13_-_27767330 1.15 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
rims1a
regulating synaptic membrane exocytosis 1a
chr14_-_32405387 1.14 ENSDART00000184647
fgf13a
fibroblast growth factor 13a
chr17_-_14671098 1.08 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr19_-_31035155 1.08 ENSDART00000161882
bzw2
basic leucine zipper and W2 domains 2
chr13_+_9432501 1.07 ENSDART00000058064
zgc:123321
zgc:123321
chr5_-_10946232 1.07 ENSDART00000163139
ENSDART00000031265
rtn4r
reticulon 4 receptor
chr6_+_36942966 1.05 ENSDART00000028895
negr1
neuronal growth regulator 1
chr1_+_10683843 1.04 ENSDART00000054879
zgc:103678
zgc:103678
chr10_-_2522588 1.03 ENSDART00000081926
CU856539.1

chr25_-_29363934 1.02 ENSDART00000166889
nptna
neuroplastin a
chr6_-_10780698 0.99 ENSDART00000151714
gpr155b
G protein-coupled receptor 155b
chr21_-_12272543 0.98 ENSDART00000081510
ENSDART00000151297
celf4
CUGBP, Elav-like family member 4
chr9_-_33107237 0.93 ENSDART00000013918
casq2
calsequestrin 2
chr4_-_23908802 0.92 ENSDART00000138873
celf2
cugbp, Elav-like family member 2
chr23_+_22658700 0.91 ENSDART00000192248
eno1a
enolase 1a, (alpha)
chr25_+_3677650 0.91 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr7_-_52334840 0.89 ENSDART00000174173
CR938716.1

chr19_-_31035325 0.87 ENSDART00000147504
bzw2
basic leucine zipper and W2 domains 2
chr10_-_2527342 0.84 ENSDART00000184168
CU856539.1

chr18_+_7264961 0.83 ENSDART00000188461
CABZ01015105.1

chr21_-_27185915 0.83 ENSDART00000135052
slc8a4a
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr5_-_51819027 0.82 ENSDART00000164267
homer1b
homer scaffolding protein 1b
chr1_-_25936677 0.82 ENSDART00000146488
ENSDART00000136321
myoz2b
myozenin 2b
chr20_+_41549200 0.80 ENSDART00000135715
fam184a
family with sequence similarity 184, member A
chr25_-_27722614 0.80 ENSDART00000190154
zgc:153935
zgc:153935
chr16_+_25245857 0.79 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr19_-_41069573 0.78 ENSDART00000111982
ENSDART00000193142
sgce
sarcoglycan, epsilon
chr1_-_21483832 0.75 ENSDART00000102790
glrba
glycine receptor, beta a
chr12_-_34035364 0.73 ENSDART00000087065
timp2a
TIMP metallopeptidase inhibitor 2a
chr25_+_29160102 0.72 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr11_+_11201096 0.71 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr2_+_19777146 0.70 ENSDART00000038648
ptbp2b
polypyrimidine tract binding protein 2b
chr9_+_29040425 0.69 ENSDART00000150201
MRAS
si:ch73-116o1.2
chr21_+_39432248 0.66 ENSDART00000179938
pafah1b1b
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr14_-_24332786 0.65 ENSDART00000173164
fam13b
family with sequence similarity 13, member B
chr5_+_64842730 0.65 ENSDART00000144732
lrrc8ab
leucine rich repeat containing 8 VRAC subunit Ab
chr17_-_50234004 0.64 ENSDART00000058706
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr24_-_28333029 0.64 ENSDART00000149015
ENSDART00000129174
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr9_+_31795343 0.64 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr5_+_51597677 0.64 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr3_-_32818607 0.63 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr14_+_24215046 0.62 ENSDART00000079215
stc2a
stanniocalcin 2a
chr5_-_72125551 0.60 ENSDART00000149412
smyd1a
SET and MYND domain containing 1a
chr5_-_18911114 0.59 ENSDART00000014434
bri3bp
bri3 binding protein
chr19_+_24394560 0.58 ENSDART00000142506
si:dkey-81h8.1
si:dkey-81h8.1
chr17_-_5769196 0.57 ENSDART00000113885
si:dkey-100n19.2
si:dkey-100n19.2
chr6_-_40722200 0.57 ENSDART00000035101
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr6_-_40722480 0.56 ENSDART00000188187
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr10_+_37145007 0.56 ENSDART00000131777
cuedc1a
CUE domain containing 1a
chr10_+_29698467 0.55 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr6_+_46697710 0.55 ENSDART00000154969
tespa1
thymocyte expressed, positive selection associated 1
chr20_-_26042070 0.55 ENSDART00000140255
si:dkey-12h9.6
si:dkey-12h9.6
chr6_-_35472923 0.55 ENSDART00000185907
rgs8
regulator of G protein signaling 8
chr5_+_61657702 0.55 ENSDART00000134387
ENSDART00000171248
ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr16_-_30655980 0.54 ENSDART00000146508
ldlrad4b
low density lipoprotein receptor class A domain containing 4b
chr23_+_23485858 0.53 ENSDART00000114067
agrn
agrin
chr3_-_18189283 0.53 ENSDART00000049240
tob1a
transducer of ERBB2, 1a
chr7_-_23745984 0.53 ENSDART00000048050
ITGB1BP2
zgc:92429
chr13_+_1944451 0.51 ENSDART00000125914
hmgcll1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr12_+_34119439 0.50 ENSDART00000032821
cyth1b
cytohesin 1b
chr12_+_41697664 0.50 ENSDART00000162302
bnip3
BCL2 interacting protein 3
chr8_-_26388090 0.49 ENSDART00000147912
si:dkey-20d21.12
si:dkey-20d21.12
chr19_+_41169996 0.49 ENSDART00000048438
asb4
ankyrin repeat and SOCS box containing 4
chr13_+_47710434 0.49 ENSDART00000188724
TMEM87B
transmembrane protein 87B
chr16_-_26435431 0.47 ENSDART00000187526
megf8
multiple EGF-like-domains 8
chr7_-_49646251 0.47 ENSDART00000193674
hrasb
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr23_-_39849155 0.47 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr5_+_61658282 0.46 ENSDART00000188878
ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr21_+_43559123 0.45 ENSDART00000151212
gpr185a
G protein-coupled receptor 185 a
chr6_-_46403475 0.44 ENSDART00000154148
camk1a
calcium/calmodulin-dependent protein kinase Ia
chr23_-_32157865 0.44 ENSDART00000000876
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr2_-_4787566 0.44 ENSDART00000160663
ENSDART00000157808
tnk2b
tyrosine kinase, non-receptor, 2b
chr8_-_53166975 0.42 ENSDART00000114683
rbsn
rabenosyn, RAB effector
chr1_-_17569793 0.42 ENSDART00000125125
acsl1a
acyl-CoA synthetase long chain family member 1a
chr7_+_39006837 0.40 ENSDART00000173735
dgkza
diacylglycerol kinase, zeta a
chr2_-_6182098 0.40 ENSDART00000156167
si:ch73-182a11.2
si:ch73-182a11.2
chr13_-_24825691 0.40 ENSDART00000142745
slka
STE20-like kinase a
chr14_+_35901249 0.37 ENSDART00000105604
zgc:77938
zgc:77938
chr9_+_32178374 0.37 ENSDART00000078576
coq10b
coenzyme Q10B
chr12_+_8373525 0.35 ENSDART00000152180
arid5b
AT-rich interaction domain 5B
chr2_-_37353098 0.35 ENSDART00000056522
skila
SKI-like proto-oncogene a
chr5_-_50781623 0.35 ENSDART00000114950
zgc:194908
zgc:194908
chr4_+_5180650 0.35 ENSDART00000067390
fgf6b
fibroblast growth factor 6b
chr9_-_23894392 0.35 ENSDART00000133417
asb18
ankyrin repeat and SOCS box containing 18
chr18_+_3169579 0.34 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr24_-_32665283 0.34 ENSDART00000038364
ca2
carbonic anhydrase II
chr12_+_27022517 0.33 ENSDART00000152975
msl1b
male-specific lethal 1 homolog b (Drosophila)
chr5_-_30151815 0.33 ENSDART00000156048
zbtb44
zinc finger and BTB domain containing 44
chr19_+_44039849 0.33 ENSDART00000086040
lrrc14b
leucine rich repeat containing 14B
chr1_-_6494384 0.33 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr17_-_23545716 0.32 ENSDART00000079534
htr7a
5-hydroxytryptamine (serotonin) receptor 7a
chr4_-_5018705 0.32 ENSDART00000154025
strip2
striatin interacting protein 2
chr23_-_36670369 0.31 ENSDART00000006881
zbtb39
zinc finger and BTB domain containing 39
chr20_-_26001288 0.30 ENSDART00000136518
ENSDART00000063177
capn3b
calpain 3b
chr9_-_48281941 0.30 ENSDART00000099787
klhl41a
kelch-like family member 41a
chr6_-_42003780 0.30 ENSDART00000032527
cav3
caveolin 3
chr19_-_7321221 0.30 ENSDART00000092375
oxr1b
oxidation resistance 1b
chr1_-_17570013 0.30 ENSDART00000146946
acsl1a
acyl-CoA synthetase long chain family member 1a
chr9_-_48937240 0.29 ENSDART00000075627
cers6
ceramide synthase 6
chr23_-_38497705 0.28 ENSDART00000109493
tshz2
teashirt zinc finger homeobox 2
chr15_-_14552101 0.27 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr24_+_9178064 0.27 ENSDART00000142971
dlgap1b
discs, large (Drosophila) homolog-associated protein 1b
chr6_+_7555614 0.27 ENSDART00000187590
myh10
myosin, heavy chain 10, non-muscle
chr22_-_26852516 0.26 ENSDART00000005829
gde1
glycerophosphodiester phosphodiesterase 1
chr17_-_10025234 0.25 ENSDART00000008355
cfl2
cofilin 2 (muscle)
chr21_+_19070921 0.25 ENSDART00000029874
nkx6.1
NK6 homeobox 1
chr3_+_60828813 0.25 ENSDART00000128260
CABZ01087514.1

chr15_+_20543770 0.25 ENSDART00000092357
sgsm2
small G protein signaling modulator 2
chr2_-_33993533 0.24 ENSDART00000140910
ENSDART00000077304
ptch2
patched 2
chr23_-_3721444 0.24 ENSDART00000141682
nudt3a
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr5_-_31875645 0.23 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr13_+_11439486 0.23 ENSDART00000138312
zbtb18
zinc finger and BTB domain containing 18
chr3_+_17456428 0.23 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
si:ch211-210g13.5
chr6_+_38896158 0.23 ENSDART00000029930
ENSDART00000131347
slc48a1b
solute carrier family 48 (heme transporter), member 1b
chr5_+_16580739 0.22 ENSDART00000135140
htr7c
5-hydroxytryptamine (serotonin) receptor 7c
chr1_-_411331 0.22 ENSDART00000092524
rasa3
RAS p21 protein activator 3
chr7_-_30143092 0.22 ENSDART00000173636
frmd5
FERM domain containing 5
chr6_-_6248893 0.22 ENSDART00000124662
rtn4a
reticulon 4a
chr10_-_41450367 0.22 ENSDART00000122682
ENSDART00000189549
cabp1b
calcium binding protein 1b
chr23_+_44497701 0.21 ENSDART00000149903
si:ch73-375g18.1
si:ch73-375g18.1
chr20_-_7000225 0.20 ENSDART00000100098
adcy1a
adenylate cyclase 1a
chr24_-_12745222 0.20 ENSDART00000151836
si:ch211-196f5.9
si:ch211-196f5.9
chr2_+_1202347 0.20 ENSDART00000075837
CABZ01084566.1

chr17_-_13026634 0.19 ENSDART00000113713
fam177a1
family with sequence similarity 177, member A1
chr23_+_6077503 0.19 ENSDART00000081714
ENSDART00000139834
mybpha
myosin binding protein Ha
chr22_-_20259309 0.18 ENSDART00000139160
si:dkey-110c1.10
si:dkey-110c1.10
chr4_+_14343706 0.17 ENSDART00000142845
prl2
prolactin 2
chr6_+_40554551 0.17 ENSDART00000017859
ENSDART00000155928
ddi2
DNA-damage inducible protein 2
chr8_+_7097929 0.17 ENSDART00000188955
ENSDART00000184772
ENSDART00000109581
abtb1
ankyrin repeat and BTB (POZ) domain containing 1
chr3_+_32425202 0.17 ENSDART00000156464
prr12b
proline rich 12b
chr25_-_29988352 0.17 ENSDART00000067059
fam19a5b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr22_+_2861734 0.16 ENSDART00000140578
si:dkey-20i20.2
si:dkey-20i20.2
chr18_+_49248389 0.16 ENSDART00000059285
ENSDART00000142004
ENSDART00000132751
yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr25_-_27722309 0.16 ENSDART00000148121
zgc:153935
zgc:153935
chr12_-_26430507 0.14 ENSDART00000153214
synpo2lb
synaptopodin 2-like b
chr7_-_27686021 0.14 ENSDART00000079112
ENSDART00000100989
calca
calcitonin/calcitonin-related polypeptide, alpha
chr19_+_30990129 0.13 ENSDART00000052169
ENSDART00000193376
sync
syncoilin, intermediate filament protein
chr5_+_51227147 0.13 ENSDART00000083340
ubac1
UBA domain containing 1
chr9_+_32178050 0.13 ENSDART00000169526
coq10b
coenzyme Q10B
chr3_-_13946446 0.13 ENSDART00000171249
gcdhb
glutaryl-CoA dehydrogenase b
chr25_+_32530976 0.12 ENSDART00000156190
ENSDART00000103324
scaper
S-phase cyclin A-associated protein in the ER
chr24_+_8904135 0.12 ENSDART00000066782
gnal
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_-_34478225 0.11 ENSDART00000189604
xxylt1
xyloside xylosyltransferase 1
chr13_+_42011287 0.10 ENSDART00000131147
cyp1b1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr9_-_52814204 0.10 ENSDART00000140771
ENSDART00000007401
MAP3K13
si:ch211-45c16.2
chr14_-_7245971 0.10 ENSDART00000108796
stox2b
storkhead box 2b
chr9_-_4018452 0.10 ENSDART00000181059
ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr1_+_59328030 0.10 ENSDART00000172464
CABZ01052576.1

chr3_-_52674089 0.10 ENSDART00000154260
ENSDART00000125455
si:dkey-210j14.4
si:dkey-210j14.4
chr4_-_4261673 0.09 ENSDART00000150694
cd9b
CD9 molecule b
chr12_+_6002715 0.09 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr9_+_24065855 0.09 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr7_+_20260172 0.09 ENSDART00000012450
dvl2
dishevelled segment polarity protein 2
chr8_-_25002182 0.08 ENSDART00000078792
ahcyl1
adenosylhomocysteinase-like 1
chr11_-_18601955 0.08 ENSDART00000180565
zmynd8
zinc finger, MYND-type containing 8
chr20_+_28407720 0.08 ENSDART00000114929
zfyve1
zinc finger, FYVE domain containing 1
chr9_+_21793565 0.08 ENSDART00000134915
rev1
REV1, polymerase (DNA directed)
chr19_-_38611814 0.06 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr7_+_31379528 0.06 ENSDART00000187370
ctdspl2b
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2b
chr11_-_26701611 0.06 ENSDART00000083010
acad9
acyl-CoA dehydrogenase family, member 9
chr15_+_17343319 0.06 ENSDART00000018461
vmp1
vacuole membrane protein 1
chr14_+_2487672 0.06 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr6_-_25201810 0.05 ENSDART00000168683
lrrc8c
leucine rich repeat containing 8 VRAC subunit C
chr1_+_19708508 0.05 ENSDART00000054581
ENSDART00000131206
march1
membrane-associated ring finger (C3HC4) 1
chr21_+_40589770 0.05 ENSDART00000164650
ENSDART00000161584
ENSDART00000161108
pdk3b
pyruvate dehydrogenase kinase, isozyme 3b
chr25_-_19486399 0.05 ENSDART00000155076
ENSDART00000156016
zgc:193812
zgc:193812
chr9_-_28399071 0.05 ENSDART00000104317
ENSDART00000064343
klf7b
Kruppel-like factor 7b
chr13_-_36581875 0.05 ENSDART00000113204
lgals3a
lectin, galactoside binding soluble 3a
chr7_+_21859337 0.05 ENSDART00000159626
si:dkey-85k7.7
si:dkey-85k7.7
chr23_+_3721042 0.04 ENSDART00000143323
smim29
small integral membrane protein 29
chr2_+_35880600 0.04 ENSDART00000004277
lamc1
laminin, gamma 1
chr1_-_45662774 0.03 ENSDART00000042158
serhl
serine hydrolase-like
chr12_+_30563550 0.03 ENSDART00000126064
si:ch211-28p3.4
si:ch211-28p3.4
chr5_-_25236340 0.03 ENSDART00000162774
abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_-_32518556 0.03 ENSDART00000103410
zbtb8b
zinc finger and BTB domain containing 8B
chr25_-_12809361 0.03 ENSDART00000162750
ca5a
carbonic anhydrase Va
chr20_+_45620076 0.03 ENSDART00000113806
hnrnpa0l
heterogeneous nuclear ribonucleoprotein A0, like
chr24_+_25471196 0.03 ENSDART00000066625
smpx
small muscle protein, X-linked
chr16_-_17200120 0.02 ENSDART00000147739
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr15_-_34866219 0.01 ENSDART00000099723
sh3bp5la
SH3-binding domain protein 5-like, a
chr24_+_26088143 0.01 ENSDART00000171129
CR352209.1

chr23_-_7826849 0.01 ENSDART00000157612
myt1b
myelin transcription factor 1b
chr4_+_13449775 0.01 ENSDART00000172552
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr18_+_17959681 0.01 ENSDART00000142700
znf423
zinc finger protein 423
chr8_+_29962635 0.00 ENSDART00000007640
ptch1
patched 1

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.9 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 2.8 GO:0016486 peptide hormone processing(GO:0016486)
0.2 0.5 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 0.9 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.2 0.5 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.2 2.5 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.7 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.3 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.8 GO:0042044 fluid transport(GO:0042044)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 1.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.4 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.1 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.6 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 1.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.0 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.2 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 1.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.5 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.1 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 2.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 0.7 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 0.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.3 GO:0031430 M band(GO:0031430)
0.1 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 2.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.1 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0042383 sarcolemma(GO:0042383)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 1.0 GO:0030018 Z disc(GO:0030018)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.2 1.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 2.5 GO:0051117 ATPase binding(GO:0051117)
0.1 5.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.5 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.8 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.1 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 1.1 GO:0002039 p53 binding(GO:0002039)
0.1 1.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.6 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0016208 AMP binding(GO:0016208)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0043236 laminin binding(GO:0043236)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.0 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 2.8 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 1.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis