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PRJNA207719: Tissue specific transcriptome profiling

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Results for mef2d

Z-value: 3.87

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Transcription factors associated with mef2d

Gene Symbol Gene ID Gene Info
mef2d
ENSDARG00000040237 myocyte enhancer factor 2d

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2ddr11_v1_chr16_-_29164379_291643790.523.7e-01Click!

Activity profile of mef2d motif

Sorted Z-values of mef2d motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_11201096 5.62 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr1_+_7546259 3.90 ENSDART00000015732
mylz3
myosin, light polypeptide 3, skeletal muscle
chr25_+_29160102 3.65 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr16_+_25245857 3.49 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr11_+_11200550 3.43 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr3_-_61205711 3.27 ENSDART00000055062
pvalb1
parvalbumin 1
chr21_+_28445052 3.19 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr23_+_20110086 3.07 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr18_+_26719787 3.04 ENSDART00000141672
alpk3a
alpha-kinase 3a
chr16_-_43356018 3.01 ENSDART00000181683
FO704821.1

chr12_-_26064105 2.98 ENSDART00000168825
ldb3b
LIM domain binding 3b
chr16_-_31919568 2.95 ENSDART00000027364
rbfox1l
RNA binding fox-1 homolog 1, like
chr6_+_29410986 2.75 ENSDART00000065293
usp13
ubiquitin specific peptidase 13
chr8_-_11112058 2.70 ENSDART00000042755
ampd1
adenosine monophosphate deaminase 1 (isoform M)
chr24_+_34089977 2.70 ENSDART00000157466
asb10
ankyrin repeat and SOCS box containing 10
chr5_-_72125551 2.69 ENSDART00000149412
smyd1a
SET and MYND domain containing 1a
chr15_-_23645810 2.66 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr12_-_17707449 2.64 ENSDART00000142427
ENSDART00000034914
pvalb3
parvalbumin 3
chr9_+_17438765 2.55 ENSDART00000138953
rgcc
regulator of cell cycle
chr5_+_51597677 2.53 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr25_+_31264155 2.48 ENSDART00000012256
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr22_-_31059670 2.44 ENSDART00000022445
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr13_+_22249636 2.44 ENSDART00000108472
ENSDART00000173123
synpo2la
synaptopodin 2-like a
chr7_+_31879649 2.38 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr16_+_29663809 2.37 ENSDART00000191336
tmod4
tropomodulin 4 (muscle)
chr23_+_24931999 2.36 ENSDART00000136162
ENSDART00000140335
klhl21
kelch-like family member 21
chr8_-_26388090 2.31 ENSDART00000147912
si:dkey-20d21.12
si:dkey-20d21.12
chr5_+_64368770 2.24 ENSDART00000162246
plpp7
phospholipid phosphatase 7 (inactive)
chr7_+_31879986 2.24 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr21_-_22730832 2.21 ENSDART00000101797
fbxo40.1
F-box protein 40, tandem duplicate 1
chr14_-_7128980 2.20 ENSDART00000171311
si:ch73-43g23.1
si:ch73-43g23.1
chr6_-_18199062 2.19 ENSDART00000167513
ppp1r27b
protein phosphatase 1, regulatory subunit 27b
chr9_-_34191627 2.17 ENSDART00000142664
dcaf6
ddb1 and cul4 associated factor 6
chr20_-_26001288 2.17 ENSDART00000136518
ENSDART00000063177
capn3b
calpain 3b
chr4_-_9592402 2.17 ENSDART00000114060
cdnf
cerebral dopamine neurotrophic factor
chr20_-_36617313 2.15 ENSDART00000172395
ENSDART00000152856
enah
enabled homolog (Drosophila)
chr12_+_6002715 2.15 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr9_-_41784799 2.14 ENSDART00000144573
ENSDART00000112542
ENSDART00000190486
obsl1b
obscurin-like 1b
chr12_-_17712393 2.13 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr19_-_31035155 2.05 ENSDART00000161882
bzw2
basic leucine zipper and W2 domains 2
chr2_-_31791633 2.05 ENSDART00000180662
retreg1
reticulophagy regulator 1
chr16_-_17200120 1.98 ENSDART00000147739
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr1_-_38815361 1.94 ENSDART00000148790
ENSDART00000148572
ENSDART00000149080
asb5b
ankyrin repeat and SOCS box containing 5b
chr24_+_34085940 1.93 ENSDART00000171189
asb10
ankyrin repeat and SOCS box containing 10
chr9_-_23894392 1.83 ENSDART00000133417
asb18
ankyrin repeat and SOCS box containing 18
chr6_-_42003780 1.83 ENSDART00000032527
cav3
caveolin 3
chr25_-_21795930 1.81 ENSDART00000127033
ppp1r3ab
protein phosphatase 1, regulatory subunit 3Ab
chr19_-_31035325 1.80 ENSDART00000147504
bzw2
basic leucine zipper and W2 domains 2
chr23_+_6077503 1.79 ENSDART00000081714
ENSDART00000139834
mybpha
myosin binding protein Ha
chr9_-_33107237 1.78 ENSDART00000013918
casq2
calsequestrin 2
chr7_+_46004893 1.77 ENSDART00000183798
si:ch211-260e23.9
si:ch211-260e23.9
chr7_+_6969909 1.76 ENSDART00000189886
actn3b
actinin alpha 3b
chr6_-_40722480 1.74 ENSDART00000188187
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr23_-_21515182 1.74 ENSDART00000142000
rnf207b
ring finger protein 207b
chr17_-_14671098 1.73 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr3_+_28953274 1.73 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr11_-_18253111 1.72 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr6_+_14301214 1.72 ENSDART00000129491
tmem182b
transmembrane protein 182b
chr9_-_23891102 1.71 ENSDART00000186799
asb18
ankyrin repeat and SOCS box containing 18
chr24_+_25471196 1.62 ENSDART00000066625
smpx
small muscle protein, X-linked
chr24_+_9298198 1.62 ENSDART00000165780
otud1
OTU deubiquitinase 1
chr6_-_40697585 1.62 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr11_+_29671661 1.61 ENSDART00000024318
ENSDART00000165024
rnf207a
ring finger protein 207a
chr12_-_26430507 1.58 ENSDART00000153214
synpo2lb
synaptopodin 2-like b
chr23_+_24926407 1.54 ENSDART00000137486
klhl21
kelch-like family member 21
chr23_-_32157865 1.52 ENSDART00000000876
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr1_-_25936677 1.52 ENSDART00000146488
ENSDART00000136321
myoz2b
myozenin 2b
chr21_-_22737228 1.49 ENSDART00000151366
fbxo40.2
F-box protein 40, tandem duplicate 2
chr23_+_22658700 1.49 ENSDART00000192248
eno1a
enolase 1a, (alpha)
chr21_-_131236 1.49 ENSDART00000160005
si:ch1073-398f15.1
si:ch1073-398f15.1
chr6_+_3680651 1.46 ENSDART00000013588
klhl41b
kelch-like family member 41b
chr25_+_16945348 1.46 ENSDART00000016591
fgf6a
fibroblast growth factor 6a
chr18_-_16791331 1.46 ENSDART00000148222
ampd3b
adenosine monophosphate deaminase 3b
chr4_-_20521441 1.40 ENSDART00000066895
rassf8b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b
chr24_-_24038800 1.39 ENSDART00000080549
lyz
lysozyme
chr17_-_10025234 1.37 ENSDART00000008355
cfl2
cofilin 2 (muscle)
chr19_+_40983221 1.32 ENSDART00000144544
col1a2
collagen, type I, alpha 2
chr2_-_6182098 1.31 ENSDART00000156167
si:ch73-182a11.2
si:ch73-182a11.2
chr24_+_38301080 1.30 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr9_-_48281941 1.27 ENSDART00000099787
klhl41a
kelch-like family member 41a
chr25_-_13381854 1.25 ENSDART00000164621
ENSDART00000169129
ndrg4
NDRG family member 4
chr4_+_6572364 1.22 ENSDART00000122574
ppp1r3aa
protein phosphatase 1, regulatory subunit 3Aa
chr2_+_6181383 1.22 ENSDART00000153307
si:ch73-344o19.1
si:ch73-344o19.1
chr2_+_9552456 1.21 ENSDART00000056896
dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr7_-_23745984 1.20 ENSDART00000048050
ITGB1BP2
zgc:92429
chr17_+_30442518 1.20 ENSDART00000155264
lpin1
lipin 1
chr21_-_25685739 1.20 ENSDART00000129619
ENSDART00000101205
phkg1b
phosphorylase kinase, gamma 1b (muscle)
chr11_-_18468570 1.19 ENSDART00000155474
ENSDART00000193869
fgd5a
FYVE, RhoGEF and PH domain containing 5a
chr8_-_32497815 1.19 ENSDART00000122359
si:dkey-164f24.2
si:dkey-164f24.2
chr1_-_38813679 1.18 ENSDART00000148917
asb5b
ankyrin repeat and SOCS box containing 5b
chr9_-_43142636 1.18 ENSDART00000134349
ENSDART00000181835
ccdc141
coiled-coil domain containing 141
chr9_+_6578580 1.13 ENSDART00000061577
fhl2a
four and a half LIM domains 2a
chr22_-_29204960 1.12 ENSDART00000131386
pvalb7
parvalbumin 7
chr14_+_23520986 1.11 ENSDART00000170473
ENSDART00000175970
si:ch211-221f10.2
si:ch211-221f10.2
chr16_+_26777473 1.11 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr3_+_24207243 1.09 ENSDART00000023454
ENSDART00000136400
adsl
adenylosuccinate lyase
chr4_-_2350371 1.07 ENSDART00000166274
phlda1
pleckstrin homology-like domain, family A, member 1
chr9_+_31795343 1.07 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr7_+_69841017 1.06 ENSDART00000169107
FO818704.1

chr9_+_32178374 1.06 ENSDART00000078576
coq10b
coenzyme Q10B
chr14_-_15699528 1.04 ENSDART00000161123
neurl1b
neuralized E3 ubiquitin protein ligase 1B
chr13_-_11536951 1.03 ENSDART00000018155
adss
adenylosuccinate synthase
chr8_-_32497581 1.01 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
si:dkey-164f24.2
chr5_-_48268049 0.98 ENSDART00000187454
mef2cb
myocyte enhancer factor 2cb
chr25_+_5039050 0.96 ENSDART00000154700
parvb
parvin, beta
chr8_-_17980317 0.96 ENSDART00000129148
tnni3k
TNNI3 interacting kinase
chr1_-_49250490 0.96 ENSDART00000150386
si:ch73-6k14.2
si:ch73-6k14.2
chr14_-_24332786 0.95 ENSDART00000173164
fam13b
family with sequence similarity 13, member B
chr5_-_51819027 0.94 ENSDART00000164267
homer1b
homer scaffolding protein 1b
chr1_+_36674584 0.94 ENSDART00000186772
ENSDART00000192274
ednraa
endothelin receptor type Aa
chr19_-_38611814 0.93 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr7_-_66864756 0.92 ENSDART00000184462
ENSDART00000189424
ampd3a
adenosine monophosphate deaminase 3a
chr7_-_48263516 0.92 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
rbpms2b
RNA binding protein with multiple splicing 2b
chr9_+_41690153 0.90 ENSDART00000100226
ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr20_+_23173710 0.90 ENSDART00000074172
sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr2_-_23768818 0.90 ENSDART00000148685
ENSDART00000191167
xirp1
xin actin binding repeat containing 1
chr13_-_28674422 0.89 ENSDART00000122754
ENSDART00000057574
nt5c2a
5'-nucleotidase, cytosolic IIa
chr21_-_22951604 0.88 ENSDART00000083449
ENSDART00000180129
dub
duboraya
chr9_+_32178050 0.88 ENSDART00000169526
coq10b
coenzyme Q10B
chr2_+_54641644 0.87 ENSDART00000027313
ndufv2
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr9_+_24065855 0.87 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr12_+_30563550 0.86 ENSDART00000126064
si:ch211-28p3.4
si:ch211-28p3.4
chr7_-_4315859 0.84 ENSDART00000172762
si:ch211-63p21.8
si:ch211-63p21.8
chr7_-_26270014 0.83 ENSDART00000079347
serpine1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr23_+_18722915 0.82 ENSDART00000025057
myh7bb
myosin, heavy chain 7B, cardiac muscle, beta b
chr7_-_28658143 0.79 ENSDART00000173556
adgrg1
adhesion G protein-coupled receptor G1
chr10_-_39153959 0.77 ENSDART00000150193
ENSDART00000111362
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr21_+_40589770 0.76 ENSDART00000164650
ENSDART00000161584
ENSDART00000161108
pdk3b
pyruvate dehydrogenase kinase, isozyme 3b
chr2_+_35880600 0.75 ENSDART00000004277
lamc1
laminin, gamma 1
chr23_+_18722715 0.75 ENSDART00000137438
myh7bb
myosin, heavy chain 7B, cardiac muscle, beta b
chr18_+_23218980 0.75 ENSDART00000185014
mef2aa
myocyte enhancer factor 2aa
chr20_+_19066858 0.74 ENSDART00000192086
sox7
SRY (sex determining region Y)-box 7
chr14_+_30285613 0.72 ENSDART00000173090
mtus1a
microtubule associated tumor suppressor 1a
chr2_-_44199722 0.72 ENSDART00000140633
ENSDART00000145728
sdhc
succinate dehydrogenase complex, subunit C, integral membrane protein
chr25_+_27923846 0.71 ENSDART00000047007
slc13a1
solute carrier family 13 member 1
chr13_-_30149973 0.71 ENSDART00000041515
sar1ab
secretion associated, Ras related GTPase 1Ab
chr14_-_30366196 0.70 ENSDART00000007022
pdgfrl
platelet-derived growth factor receptor-like
chr11_+_13207898 0.69 ENSDART00000060310
atp5f1b
ATP synthase F1 subunit beta
chr5_+_66132394 0.69 ENSDART00000073892
zgc:114041
zgc:114041
chr25_+_3677650 0.68 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr11_-_22303678 0.67 ENSDART00000159527
ENSDART00000159681
tfeb
transcription factor EB
chr15_-_34458495 0.67 ENSDART00000059954
meox2a
mesenchyme homeobox 2a
chr19_+_44039849 0.65 ENSDART00000086040
lrrc14b
leucine rich repeat containing 14B
chr17_-_15611744 0.65 ENSDART00000010496
fhl5
four and a half LIM domains 5
chr20_-_38836161 0.64 ENSDART00000061358
si:dkey-221h15.4
si:dkey-221h15.4
chr3_-_18189283 0.64 ENSDART00000049240
tob1a
transducer of ERBB2, 1a
chr1_-_11075403 0.64 ENSDART00000102903
ENSDART00000170290
dmd
dystrophin
chr23_-_27479558 0.63 ENSDART00000013563
atf7a
activating transcription factor 7a
chr24_+_20575259 0.63 ENSDART00000010488
klhl40b
kelch-like family member 40b
chr22_+_15898221 0.62 ENSDART00000062587
klf2a
Kruppel-like factor 2a
chr16_-_32975951 0.62 ENSDART00000101969
ENSDART00000175149
me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr16_+_34523515 0.62 ENSDART00000041007
stmn1b
stathmin 1b
chr5_+_51227147 0.61 ENSDART00000083340
ubac1
UBA domain containing 1
chr16_+_5259886 0.61 ENSDART00000186668
plecb
plectin b
chr19_-_25519612 0.61 ENSDART00000133150
C1GALT1 (1 of many)
si:dkey-202e17.1
chr14_-_30704075 0.59 ENSDART00000134098
efemp2a
EGF containing fibulin extracellular matrix protein 2a
chr6_+_57541776 0.57 ENSDART00000157330
necab3
N-terminal EF-hand calcium binding protein 3
chr9_-_23990416 0.57 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr1_-_41982582 0.56 ENSDART00000014678
adra1d
adrenoceptor alpha 1D
chr20_-_39271844 0.56 ENSDART00000192708
clu
clusterin
chr6_-_54111928 0.55 ENSDART00000083880
hyal2a
hyaluronoglucosaminidase 2a
chr24_+_8736497 0.55 ENSDART00000181904
tmem14ca
transmembrane protein 14Ca
chr10_-_22803740 0.55 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr6_-_15101477 0.54 ENSDART00000187713
ENSDART00000124132
fhl2b
four and a half LIM domains 2b
chr6_-_30932078 0.54 ENSDART00000028612
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr22_+_16497670 0.53 ENSDART00000014330
ier5
immediate early response 5
chr23_-_39849155 0.53 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr22_+_336256 0.53 ENSDART00000019155
btg2
B-cell translocation gene 2
chr12_+_41697664 0.53 ENSDART00000162302
bnip3
BCL2 interacting protein 3
chr19_-_3925801 0.53 ENSDART00000129570
ENSDART00000163138
si:ch73-281i18.6
si:ch73-281i18.6
chr13_-_24825691 0.52 ENSDART00000142745
slka
STE20-like kinase a
chr4_+_14717502 0.52 ENSDART00000067031
kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
chr21_+_34929598 0.51 ENSDART00000135806
si:dkey-71d15.2
si:dkey-71d15.2
chr14_+_29780113 0.50 ENSDART00000173195
zgc:153146
zgc:153146
chr4_+_5848229 0.50 ENSDART00000161101
ENSDART00000067357
lyrm5a
LYR motif containing 5a
chr1_+_18965750 0.48 ENSDART00000132379
limch1a
LIM and calponin homology domains 1a
chr9_-_12424791 0.48 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr10_+_8767541 0.48 ENSDART00000170272
itga1
integrin, alpha 1
chr21_+_27448856 0.47 ENSDART00000100784
cfbl
complement factor b-like
chr5_-_37881345 0.47 ENSDART00000084819
arhgap35b
Rho GTPase activating protein 35b
chr6_-_6248893 0.46 ENSDART00000124662
rtn4a
reticulon 4a
chr11_-_3860534 0.46 ENSDART00000082425
gata2a
GATA binding protein 2a
chr19_-_25464291 0.44 ENSDART00000112915
umad1
UBAP1-MVB12-associated (UMA) domain containing 1
chr18_-_25177230 0.44 ENSDART00000013363
slco3a1
solute carrier organic anion transporter family, member 3A1
chr24_+_26276805 0.44 ENSDART00000089749
adipoqa
adiponectin, C1Q and collagen domain containing, a
chr21_+_34981263 0.43 ENSDART00000132711
rbm11
RNA binding motif protein 11
chr24_-_28333029 0.42 ENSDART00000149015
ENSDART00000129174
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr25_+_31222069 0.41 ENSDART00000159373
tnni2a.1
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr21_-_32487061 0.41 ENSDART00000114359
ENSDART00000131591
ENSDART00000131477
si:dkeyp-72g9.4
si:dkeyp-72g9.4
chr23_-_23401305 0.41 ENSDART00000078936
her9
hairy-related 9
chr19_-_42566527 0.40 ENSDART00000147818
ENSDART00000142135
si:dkey-228a15.1
si:dkey-228a15.1
chr17_-_20118145 0.38 ENSDART00000149737
ENSDART00000165606
ryr2b
ryanodine receptor 2b (cardiac)
chr6_-_25201810 0.38 ENSDART00000168683
lrrc8c
leucine rich repeat containing 8 VRAC subunit C
chr8_+_30456161 0.38 ENSDART00000085894
pgm5
phosphoglucomutase 5
chr10_-_39154594 0.37 ENSDART00000148825
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr7_+_59212666 0.36 ENSDART00000172046
dok1b
docking protein 1b
chr1_+_10720294 0.34 ENSDART00000139387
atp1b1b
ATPase Na+/K+ transporting subunit beta 1b
chr7_-_21905851 0.34 ENSDART00000111066
ENSDART00000020288
epoa
erythropoietin a
chr22_-_22164338 0.34 ENSDART00000183840
cdc34a
cell division cycle 34 homolog (S. cerevisiae) a
chr15_+_31886284 0.33 ENSDART00000156706
frya
furry homolog a (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2d

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.9 4.6 GO:0003210 cardiac atrium formation(GO:0003210)
0.8 2.4 GO:0010265 SCF complex assembly(GO:0010265)
0.7 2.2 GO:0097264 self proteolysis(GO:0097264)
0.7 2.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.6 1.7 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.5 1.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 1.8 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.4 3.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.4 5.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.4 5.1 GO:0032264 IMP salvage(GO:0032264)
0.3 1.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.3 2.7 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 2.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 0.9 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 1.8 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 3.8 GO:0034629 cellular protein complex localization(GO:0034629)
0.2 1.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 0.6 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.2 0.6 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.2 0.8 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.2 2.0 GO:0061709 reticulophagy(GO:0061709)
0.2 1.8 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.2 0.9 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.2 0.7 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.2 1.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 2.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 1.5 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 4.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.2 0.9 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2 0.5 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.2 4.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 2.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 3.0 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.7 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.1 0.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.8 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 6.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.7 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 2.0 GO:0014823 response to activity(GO:0014823)
0.1 1.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 5.6 GO:0006096 glycolytic process(GO:0006096)
0.1 1.9 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.5 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.1 0.6 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.1 1.7 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 4.8 GO:0010842 retina layer formation(GO:0010842)
0.1 1.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 0.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.4 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 7.5 GO:0006936 muscle contraction(GO:0006936)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.2 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.4 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 1.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.8 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.2 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 1.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.0 2.7 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.1 GO:0003207 cardiac chamber formation(GO:0003207)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.5 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 1.2 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.1 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 1.8 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.1 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 1.0 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.3 GO:0051597 response to methylmercury(GO:0051597)
0.0 1.1 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.4 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.0 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.3 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 1.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.2 GO:1902656 calcium ion transmembrane import into cytosol(GO:0097553) calcium ion import into cytosol(GO:1902656)
0.0 1.0 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 0.7 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0070378 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 6.7 GO:0016567 protein ubiquitination(GO:0016567)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 13.4 GO:0031430 M band(GO:0031430)
0.3 1.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 1.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 3.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 1.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 8.3 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 0.7 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 4.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 11.8 GO:0030018 Z disc(GO:0030018)
0.1 3.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.5 GO:0016460 myosin II complex(GO:0016460)
0.1 0.7 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.3 GO:0097541 axonemal basal plate(GO:0097541)
0.1 2.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.1 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 3.0 GO:0042383 sarcolemma(GO:0042383)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.6 3.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 2.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.5 5.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 5.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 1.8 GO:0071253 connexin binding(GO:0071253)
0.4 5.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 1.4 GO:0003796 lysozyme activity(GO:0003796)
0.3 1.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 1.9 GO:0048039 ubiquinone binding(GO:0048039)
0.2 1.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 0.7 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.2 1.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 3.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 2.2 GO:0005522 profilin binding(GO:0005522)
0.2 3.0 GO:2001069 glycogen binding(GO:2001069)
0.2 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 2.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 1.7 GO:0016936 galactoside binding(GO:0016936)
0.2 0.6 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 1.5 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 3.0 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.6 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 1.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 3.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.3 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.7 GO:0002039 p53 binding(GO:0002039)
0.1 0.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.6 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 1.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 4.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.0 11.5 GO:0051015 actin filament binding(GO:0051015)
0.0 1.9 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0070330 aromatase activity(GO:0070330)
0.0 2.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 1.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 5.0 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.1 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 10.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 6.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 1.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 1.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 2.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo