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PRJNA207719: Tissue specific transcriptome profiling

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Results for mta3

Z-value: 0.48

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Transcription factors associated with mta3

Gene Symbol Gene ID Gene Info
ENSDARG00000054903 metastasis associated 1 family, member 3
ENSDARG00000113436 metastasis associated 1 family, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mta3dr11_v1_chr12_+_25223843_252238730.801.0e-01Click!

Activity profile of mta3 motif

Sorted Z-values of mta3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25187210 0.50 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
chr1_+_15062 0.23 ENSDART00000169005
centrosomal protein 97
chr5_-_38170996 0.18 ENSDART00000145805
si:ch211-284e13.12
chr7_+_1579510 0.16 ENSDART00000190525
SPT16 homolog, facilitates chromatin remodeling subunit
chr7_+_1579236 0.14 ENSDART00000172830
SPT16 homolog, facilitates chromatin remodeling subunit
chr8_+_27555314 0.14 ENSDART00000135568
ENSDART00000016696
ras homolog family member Cb
chr4_+_77971104 0.13 ENSDART00000188609
zgc:113921
chr13_+_23093743 0.13 ENSDART00000148034
phosphoinositide-3-kinase adaptor protein 1
chr2_-_16359042 0.12 ENSDART00000057216
Rho guanine nucleotide exchange factor (GEF) 4
chr22_+_26703026 0.10 ENSDART00000158756
CREB binding protein a
chr16_-_23800484 0.09 ENSDART00000139964
ribosomal protein S27, isoform 2
chr21_+_45712247 0.09 ENSDART00000163982
calcium modulating ligand
chr7_+_1467863 0.09 ENSDART00000173433
ER membrane protein complex subunit 4
chr25_-_35106751 0.08 ENSDART00000180682
ENSDART00000073457
zgc:194989
chr20_-_33675676 0.07 ENSDART00000147168
rho-associated, coiled-coil containing protein kinase 2b
chr5_+_66433287 0.07 ENSDART00000170757
kinetochore associated 1
chr20_+_9474841 0.07 ENSDART00000053847
RAD51 paralog B
chr22_-_367569 0.06 ENSDART00000041895
SSU72 homolog, RNA polymerase II CTD phosphatase
chr17_-_25630822 0.06 ENSDART00000126201
ENSDART00000105503
ENSDART00000151878
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr13_+_1100197 0.06 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr15_-_25198107 0.05 ENSDART00000159793
MAX network transcriptional repressor a
chr12_+_13348918 0.05 ENSDART00000181373
ribonuclease type III, nuclear
chr16_+_11029762 0.05 ENSDART00000091183
Ets2 repressor factor like 3
chr10_-_43928937 0.05 ENSDART00000168014
ENSDART00000086220
multiple C2 domains, transmembrane 1b
chr6_+_3334710 0.05 ENSDART00000132848
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr1_+_14454663 0.05 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr20_-_14665002 0.05 ENSDART00000152816
secernin 2
chr5_+_20453874 0.04 ENSDART00000124545
ENSDART00000008402
squamous cell carcinoma antigen recognized by T cells 3
chr4_+_69577362 0.04 ENSDART00000160913
zinc finger protein 1030
chr5_+_45139196 0.04 ENSDART00000113738
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_45138934 0.04 ENSDART00000041412
ENSDART00000136002
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_+_1550966 0.04 ENSDART00000177863
ENSDART00000126840
SPT16 homolog, facilitates chromatin remodeling subunit
chr16_-_280835 0.04 ENSDART00000190541

chr22_+_344763 0.04 ENSDART00000181934

chr20_-_51727860 0.04 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr2_+_13069168 0.04 ENSDART00000192832
protein kinase, AMP-activated, gamma 2 non-catalytic subunit b
chr21_+_44581654 0.03 ENSDART00000187201
ENSDART00000180360
ENSDART00000191543
ENSDART00000180039
ENSDART00000186308
transmembrane protein 164
chr18_-_45736 0.03 ENSDART00000148373
ENSDART00000148950
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr20_-_54435287 0.03 ENSDART00000148632
YY1 transcription factor b
chr3_-_5228137 0.03 ENSDART00000137105
myosin, heavy chain 9b, non-muscle
chr2_-_56095275 0.03 ENSDART00000154701
si:ch211-178n15.1
chr10_-_9115383 0.02 ENSDART00000139324
si:dkeyp-41f9.3
chr22_-_193234 0.01 ENSDART00000131067
F-box protein 42
chr16_+_13822137 0.01 ENSDART00000163251
folliculin
chr13_+_31545812 0.01 ENSDART00000076527
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr5_-_54712159 0.01 ENSDART00000149207
cyclin B1
chr18_-_46010 0.01 ENSDART00000052641
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr14_-_237130 0.01 ENSDART00000164988
biorientation of chromosomes in cell division 1-like 1
chr13_-_10431476 0.01 ENSDART00000133968
calmodulin-lysine N-methyltransferase
chr11_-_20956309 0.00 ENSDART00000188659

chr8_+_43056153 0.00 ENSDART00000186377
prion protein a
chr23_+_2825940 0.00 ENSDART00000135781
phospholipase C, gamma 1
chr12_-_290413 0.00 ENSDART00000152496
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent

Network of associatons between targets according to the STRING database.

First level regulatory network of mta3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.0 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.0 0.0 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery